γ-Aminobutyrate- and Glutamate-gated Chloride Channels as Targets of Insecticides

Advances in Insect Physiology

Volumn 44, Issue , 2013, Pages 211-286

  Ozoe, Yoshihisa ^a  

^a SHIMANE UNIVERSITY   (Japan)

Author keywords

GABA; GABA gated chloride channel; Glutamate; Glutamate gated chloride channel; Glutamic acid; Inhibitory neurotransmitters; Insect; Insecticide; Receptor; Aminobutyrate

Indexed keywords

EID: 84873493021     PISSN: 00652806     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-12-394389-7.00004-1     Document Type: Chapter

References (396)

1. Abraham M.H., Enomoto K., Clarke E.D., Sexton G. Hydrogen bond basicity of the chlorogroup; hexachlorocyclohexanes as strong hydrogen bond bases. J. Org. Chem. 2002, 67:4782-4786.
2. A receptor by the insecticide ivermectin. Eur. J. Pharmacol. 2000, 394:163-170.
3. A receptor desensitization uncouples sleep onset and maintenance in Drosophila. Nat. Neurosci. 2008, 11:354-359.
4. Ahn Y.J., Kwon M., Park H.M., Han C.K. Potent insecticidal activity of Ginkgo biloba derived trilactone terpenes against Nilaparvata lugens. ACS Symposium Series 658 1997, 90-105. American Chemical Society, Washington, DC. P.A. Hedin, R.M. Hollingworth, E.P. Masler, J. Miyamoto, D.G. Thompson (Eds.).
5. Akamatsu M., Ozoe Y., Ueno T., Fujita T., Mochida K., Nakamura T., Matsumura F. Sites of action of noncompetitive GABA antagonists in houseflies and rats: three-dimensional QSAR analysis. Pestic. Sci. 1997, 49:319-332.
6. A receptor subunits in peripheral tissues. Neurosci. Res. 1999, 35:145-153.
7. Alam M.S., Kajiki R., Hanatani H., Kong X., Ozoe F., Matsui Y., Matsumura F., Ozoe Y. Synthesis and structure-activity relationships of 1-phenyl-1H-1,2,3-triazoles as selective insect GABA receptor antagonists. J. Agric. Food Chem. 2006, 54:1361-1372.
8. Alam M.S., Huang J., Ozoe F., Matsumura F., Ozoe Y. Synthesis, 3D-QSAR, and docking studies of 1-phenyl-1H-1,2,3-triazoles as selective antagonists for β3 over α1β2γ2 GABA receptors. Bioorg. Med. Chem. 2007, 15:5090-5104.
9. - current in cockroach dorsal unpaired median neurons. J. Neurophysiol. 2002, 87:2972-2982.
10. Alqazzaz M., Thompson A.J., Price K.L., Breitinger H.-G., Lummis S.C.R. Cys-loop receptor channel blockers also block GLIC. Biophys. J. 2011, 101:2912-2918.
11. Amat C., Hue B. Activation of picrotoxin-resistant GABA receptors by GABA and related compounds induces modulation of cockroach dorsal paired median (DPM) neuron firing. J. Insect Physiol. 1997, 43:1125-1131.
12. Anthony N.M., Brown J.K., Markham P.G., ffrench-Constant R.H. Molecular analysis of cyclodiene resistance-associated mutations among populations of the sweetpotato whitefly Bemisia tabaci. Pestic. Biochem. Physiol. 1995, 51:220-228.
13. Anthony N., Unruh T., Ganser D., ffrench-Constant R. Duplication of the Rdl GABA receptor subunit gene in an insecticide-resistant aphid, Myzus persicae. Mol. Gen. Genet. 1998, 260:165-175.
14. Aronstein K., ffrench-Constant R. Immunocytochemistry of a novel GABA receptor subunit Rdl in Drosophila melanogaster. Invert. Neurosci. 1995, 1:25-31.
15. Aronstein K., Auld V., ffrench-Constant R. Distribution of two GABA receptor-like subunits in the Drosophila CNS. Invert. Neurosci. 1996, 2:115-120.
16. Ashby J.A., McGonigle I.V., Price K.L., Cohen N., Comitani F., Dougherty D.A., Molteni C., Lummis S.C.R. GABA binding to an insect GABA receptor: a molecular dynamics and mutagenesis study. Biophys. J. 2012, 103:2071-2081.
17. Asih P.B.S., Syahrani L., Rozi I.E.P., Pratama N.R., Marantina S.S., Arsyad D.S., Mangunwardoyo W., Hawley W., Laihad F., Shinta, Sukowati S., Lobo N.F., Syafruddin D. Existence of the rdl mutant alleles among the Anopheles malaria vector in Indonesia. Malar. J. 2012, 11:57.
18. A receptors expressed in Xenopus oocytes. J. Pharmacol. Exp. Ther. 1997, 282:1557-1564.
19. Awapara J., Landua A.J., Fuerst R., Seale B. Free γ-aminobutyric acid in brain. J. Biol. Chem. 1950, 187:35-39.
20. Aydar E., Beadle D.J. The pharmacological profile of GABA receptors on cultured insect neurones. J. Insect Physiol. 1999, 45:213-219.
21. B receptor on an identified insect motor neurone. J. Exp. Biol. 1995, 198:889-894.
22. Barbara G.S., Zube C., Rybak J., Gauthier M., Grünewald B. Acetylcholine, GABA and glutamate induce ionic currents in cultured antennal lobe neurons of the honeybee, Apis mellifera. J. Comp. Physiol. A 2005, 191:823-836.
23. A receptors: classification on the basis of subunit structure and receptor function. Pharmacol. Rev. 1998, 50:291-313.
24. Bass C., Schroeder I., Turnberg A., Field L.M., Williamson M.S. Identification of the Rdl mutation in laboratory and field strains of the cat flea, Ctenocephalides felis (Siphonaptera: Pulicidae). Pest Manag. Sci. 2004, 60:1157-1162.
25. Bazemore A.W., Elliott K.A.C., Florey E. Isolation of factor I. J. Neurochem. 1957, 1:334-339.
26. Beg A.A., Jorgensen E.M. EXP-1 is an excitatory GABA-gated cation channel. Nat. Neurosci. 2003, 6:1145-1152.
27. Belelli D., Callachan H., Hill-Venning C., Peters J.A., Lambert J.J. Interaction of positive allosteric modulators with human and Drosophila recombinant GABA receptors expressed in Xenopus laevis oocytes. Br. J. Pharmacol. 1996, 118:563-576.
28. Benson J.A. A novel GABA receptor in the heart of a primitive arthropod, Limulus polyphemus. J. Exp. Biol. 1989, 147:421-438.
29. Bermudez I., Hawkins C.A., Taylor A.M., Beadle D.J. Actions of insecticides on the insect GABA receptor complex. J. Recept. Res. 1991, 11:221-232.
30. Bertrand D., Gopalakrishnan M. Allosteric modulation of nicotinic acetylcholine receptors. Biochem. Pharmacol. 2007, 74:1155-1163.
31. B receptors. Physiol. Rev. 2004, 84:835-867.
32. Bloomquist J.R. Cyclodiene resistance at the insect GABA receptor/chloride channel complex confers broad cross resistance to convulsants and experimental phenylpyrazole insecticides. Arch. Insect Biochem. Physiol 1994, 26:69-79.
33. Bloomquist J.R. GABA and glutamate receptors as biochemical sites for insecticide action. Biochemical Sites of Insecticide Action and Resistance 2001, 17-41. Springer-Verlag, Berlin. I. Ishaaya (Ed.).
34. A receptor/chloride channel complex. Pestic. Biochem. Physiol. 2008, 91:17-23.
35. Bocquet N., Nury H., Baaden M., Le Poupon C., Changeux J.-P., Delarue M., Corringer P.-J. X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation. Nature 2008, 457:111-114.
36. B receptors as potential targets for drugs able to prevent excessive excitatory amino acid transmission in the spinal cord. Eur. J. Pharmacol. 1998, 362:143-148.
37. Bowery N.G., Collins J.F., Hill R.G. Bicyclic phosphorus esters that are potent convulsants and GABA antagonists. Nature 1976, 261:601-603.
38. B receptors: structure and function. Pharmacol. Rev. 2002, 54:247-264.
39. Brejc K., van Dijk W.J., Klaassen R.V., Schuurmans M., van der Oost J., Smit A.B., Sixma T.K. Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors. Nature 2001, 411:269-276.
40. Brotz T.M., Borst A. Cholinergic and GABAergic receptors on fly tangential cells and their role in visual motion detection. J. Neurophysiol. 1996, 76:1786-1799.
41. Brotz T.M., Bochenek B., Aronstein K., ffrench-Constant R.H., Borst A. γ-Aminobutyric acid receptor distribution in the mushroom bodies of a fly (Calliphora erythrocephala): a functional subdivision of Kenyon cells?. J. Comp. Neurol. 1997, 383:42-48.
42. Brotz T.M., Gundelfinger E.D., Borst A. Cholinergic and GABAergic pathways in fly motion vision. BMC Neurosci. 2001, 2:1.
43. Brunet S., Le Meter C., Murray M., Soll M., Audonnet J.-C. Rdl gene polymorphism and sequence analysis and relation to in vivo fipronil susceptibility in strains of the cat flea. J. Econ. Entomol. 2009, 102:366-372.
44. Buckingham S.D., Sattelle D.B. GABA receptors of insects. Comprehensive Molecular Insect Science 2004, 107-142. Elsevier Pergamon, Amsterdam, The Netherland. K. Iatrou, S.S. Gill, L.I. Gilbert (Eds.).
45. Buckingham S.D., Sattelle D.B. GABA receptors of insects. Insect Pharmacology: Channels, Receptors, Toxins and Enzymes 2010, 29-64. Elsevier Academic Press, London. L.I. Gilbert, S.S. Gill (Eds.).
46. Buckingham S.D., Matsuda K., Hosie A.M., Baylis H.A., Squire M.D., Lansdell S.J., Millar N.S., Sattelle D.B. Wild-type and insecticide-resistant homo-oligomeric GABA receptors of Drosophila melanogaster stably expressed in a Drosophila cell line. Neuropharmacology 1996, 35:1393-1401.
47. Buckingham S.D., Biggin P.C., Sattelle B.M., Brown L.A., Sattelle D.B. Insect GABA receptors: splicing, editing, and targeting by antiparasitics and insecticides. Mol. Pharmacol. 2005, 68:942-951.
48. Buckingham S.D., Higashino Y., Sattelle D.B. Allosteric modulation by benzodiazepines of GABA-gated chloride channels of an identified insect motor neurone. Invert. Neurosci. 2009, 9:85-89.
49. Casida J.E., Eto M., Moscioni A.D., Engel J.L., Milbrath D.S., Verkade J.G. Structure-toxicity relationships of 2,6,7-trioxabicyclo[2.2.2]octanes and related compounds. Toxicol. Appl. Pharmacol. 1976, 36:261-279.
50. Cayre M., Buckingham S.D., Yagodin S., Sattelle D.B. Cultured insect mushroom body neurons express functional receptors for acetylcholine, GABA, glutamate, octopamine and dopamine. J. Neurophysiol. 1999, 81:1-14.
51. Chen R., Belelli D., Lambert J.J., Peters J.A., Reyes A., Lan N.C. Cloning and functional expression of a Drosophila γ-aminobutyric acid receptor. Proc. Natl. Acad. Sci. U.S.A. 1994, 91:6069-6073.
52. Chen L., Durkin K.A., Casida J.E. Structural model for γ-aminobutyric acid receptor noncompetitive antagonist binding: widely diverse structures fit the same site. Proc. Natl. Acad. Sci. U.S.A. 2006, 103:5185-5190.
53. A receptor M2 extracellular half relative to noncompetitive antagonist action. J. Biol. Chem. 2006, 281:38871-38878.
54. Choudhary A.F., Laycock I., Wright G.A. γ-Aminobutyric acid receptor A-mediated inhibition in the honeybee's antennal lobe is necessary for the formation of configural olfactory percepts. Eur. J. Neurosci. 2012, 35:1718-1724.
55. A receptor RDL acts in peptidergic PDF neurons to promote sleep in Drosophila. Curr. Biol. 2009, 19:386-390.
56. Ci S., Ren T., Su Z. Modeling the interaction of fipronil-related non-competitive antagonists with the GABA β3-receptor. J. Mol. Model. 2007, 13:457-464.
57. Cleland T.A. Inhibitory glutamate receptor channels. Mol. Neurobiol. 1996, 13:97-136.
58. 3H]EBOB) in vertebrate brain and insect head. Pestic. Biochem. Physiol. 1992, 44:1-8.
59. Cole L.M., Nicholson R.A., Casida J.E. Action of phenylpyrazole insecticides at the GABA-gated chloride channel. Pestic. Biochem. Physiol. 1993, 46:47-54.
60. 3H]EBOB binding site associated with Ala→Ser or Gly mutants of Rdl subunit. Life Sci. 1995, 56:757-765.
61. Collins T., Millar N.S. Nicotinic acetylcholine receptor transmembrane mutations convert ivermectin from a positive to a negative allosteric modulator. Mol. Pharmacol. 2010, 78:198-204.
62. Colliot F., Kukorowski K.A., Hawkins D.W., Roberts D.A. Fipronil: a new soil and foliar broad spectrum insecticide 1992, 29-34.
63. Cordova D., Rauh J.J., Benner E.A., Schroeder M.E., Sopa J.S., Lahm G.P., Pahutski T.F., Long J.K., Holyoke C.W., Smith R.M., Barry J.D., Dung M.H. Isoxazoline insecticides: a novel class of GABA-gated chloride channel blockers. 12th IUPAC International Congress of Pesticide Chemistry 2010, Royal Australian Chemical Institute, North Melbourne, No. 265.
64. Cramer R.D., Patterson D.E., Bunce J.D. Comparative molecular field analysis (CoMFA). 1. Effect of shape on binding of steroids to carrier proteins. J. Am. Chem. Soc. 1988, 110:5959-5967.
65. Cull-Candy S.G. Two types of extrajunctional L-glutamate receptors in locust muscle fibres. J. Physiol. 1976, 255:449-464.
66. Cull-Candy S.G., Miledi F.R.S. Junctional and extrajunctional membrane channels activated by GABA in locust muscle fibres. Proc. R. Soc. Lond. B Biol. Sci. 1981, 211:527-535.
67. Cull-Candy S.G., Usherwood P.N.R. Two populations of L-glutamate receptors on locust muscle fibres. Nat. New Biol. 1973, 246:62-64.
68. Cully D.F., Vassilatis D.K., Liu K.K., Paress P.S., Van der Ploeg L.H.T., Schaeffer J.M., Arena J.P. Cloning of an avermectin-sensitive glutamate-gated chloride channel from Caenorhabditis elegans. Nature 1994, 371:707-711.
69. Cully D.F., Paress P.S., Liu K.K., Schaeffer J.M., Arena J.P. Identification of a Drosophila melanogaster glutamate-gated chloride channel sensitive to the antiparasitic agent avermectin. J. Biol. Chem. 1996, 271:20187-20191.
70. Das P., Dillon G.H. Molecular determinants of picrotoxin inhibition of 5-hydroxytryptamine type 3 receptors. J. Pharmacol. Exp. Ther. 2005, 314:320-328.
71. A receptor antagonist picrotoxin inhibits 5-hydroxytryptamine type 3A receptors. Neuropharmacology 2003, 44:431-438.
72. Das S., Sadanandappa M.K., Dervan A., Larkin A., Lee J.A., Sudhakaran I.P., Priya R., Heidari R., Holohan E.E., Pimentel A., Gandhi A., Ito K., Sanyal S., Wang J.W., Rodrigues V., Ramaswami M. Plasticity of local GABAergic interneurons drives olfactory habituation. Proc. Natl. Acad. Sci. USA 2011, 108:E646-E654.
73. A receptor. J. Pharmacol. Exp. Ther. 2000, 295:1051-1060.
74. Delany N.S., Laughton D.L., Wolstenholme A.J. Cloning and localisation of an avermectin receptor-related subunit from Haemonchus contortus. Mol. Biochem. Parasitol. 1998, 97:177-187.
75. Deng Y., Palmer C.J., Casida J.E. House fly brain γ-aminobutyric acid-gated chloride channel: target for multiple classes of insecticides. Pestic. Biochem. Physiol. 1991, 41:60-65.
76. Dent J.A., Davis M.W., Avery L. avr-15 encodes a chloride channel subunit that mediates inhibitory glutamatergic neurotransmission and ivermectin sensitivity in Caenorhabditis elegans. EMBO J. 1997, 16:5867-5879.
77. Démares F., Raymond V., Armengaud C. Expression and localization of glutamate-gated chloride channel variants in honeybee brain (Apis mellifera). Insect Biochem. Mol. Biol 2012, 10.1016/j.ibmb.2012.10.003.
78. Dermauw W., Ilias A., Riga M., Tsagkarakou A., Grbić M., Tirry L., Van Leeuwen T., Vontas J. The cys-loop ligand-gated ion channel gene family of Tetranychus urticae: implications for acaricide toxicology and a novel mutation associated with abamectin resistance. Insect Biochem. Mol. Biol. 2012, 42:455-465.
79. B receptors are involved in behavioral effects of γ-hydroxylbutyric acid (GHB). Eur. J. Pharmacol. 2005, 519:246-252.
80. Du W., Awolola T.S., Howell P., Koekemoer L.L., Brooke B.D., Benedict M.Q., Cowtzee M., Zheng L. Independent mutations in the Rdl locus confer dieldrin resistance to Anopheles gambiae and An. arabiensis. Insect Mol. Biol. 2005, 14:179-183.
81. Dubreil V., Sinakevitch I.G., Hue B., Geffard M. Neuritic GABAergic synapses in insect neurosecretory cells. Neurosci. Res. 1994, 19:235-240.
82. 1a on insect muscle. Br. J. Pharmacol. 1985, 85:395-401.
83. Duittoz A.H., Martin R.J. Antagonist properties of arylaminopyridazine GABA derivatives at the Ascaris muscle GABA receptor. J. Exp. Biol. 1991, 159:149-164.
84. Dupuis J.P., Bazelot M., Barbara G.S., Paute S., Gauthier M., Raymond-Delpech V. Homomeric RDL and heteromeric RDL/LCCH3 GABA receptors in the honeybee antennal lobes: two candidates for inhibitory transmission in olfactory processing. J. Neurophysiol. 2010, 103:458-468.
85. Dzitoyeva S., Dimitrijevic N., Manev H. γ-Aminobutyric acid B receptor 1 mediates behavior-impairing actions of alcohol in Drosophila: adult RNA interference and pharmacological evidence. Proc. Natl. Acad. Sci. U.S.A. 2003, 100:5485-5490.
86. B(1) receptors in Drosophila. Dev. Brain Res. 2005, 158:111-114.
87. Eguchi Y., Ihara M., Ochi E., Shibata Y., Matsuda K., Fushiki S., Sugama H., Hamasaki Y., Niwa H., Wada M., Ozoe F., Ozoe Y. Functional characterization of Musca glutamate- and GABA-gated chloride channels expressed independently and coexpressed in Xenopus oocytes. Insect Mol. Biol. 2006, 15:773-783.
88. El Hassani A.K., Dupuis J.P., Gauthier M., Armengaud C. Glutamatergic and GABAergic effects of fipronil on olfactory learning and memory in the honeybee. Invert. Neurosci. 2009, 9:91-100.
89. El Hassani A.K., Schuster S., Dyck Y., Demares F., Leboulle G., Armengaud C. Identification, localization and function of glutamate-gated chloride channel receptors in the honeybee brain. Eur. J. Neurosci. 2012, 36:2409-2420.
90. A receptor subunit RDL and a vesicular GABA transporter. J. Comp. Neurol. 2007, 505:18-31.
91. Enna S.J. The GABA receptors. The GABA Receptors 2007, 1-21. Humana Press, Totowa, NJ. third ed. S.J. Enna, H. Möhler (Eds.).
92. AR reveal a pattern of hydrogen bonding with picrotoxin. Biophys. J. 2008, 94:4299-4306.
93. Ernst E. The efficacy of herbal medicine-an overview. Fund. Clin. Pharmacol. 2005, 19:405-409.
94. Es-Salah Z., Lapied B., Le Goff G., Hamon A. RNA editing regulates insect gamma-aminobutyric acid receptor function and insecticide sensitivity. Neuroreport 2008, 19:939-943.
95. Eto M. Development of insecticidal cyclic phosphoryl compounds through chemical and biochemical approaches. J. Environ. Sci. Health B 1983, 18:119-145.
96. Eto M., Ozoe Y., Fujita T., Casida J.E. Significance of branched bridge-head substituent in toxicity of bicyclic phosphate esters. Agric. Biol. Chem. 1976, 40:2113-2115.
97. Etter A., Cully D.F., Liu K.K., Reiss B., Vassilatis D.K., Schaeffer J.M., Arena J.P. Picrotoxin blockade of invertebrate glutamate-gated chloride channels: subunit dependence and evidence for binding within the pore. J. Neurochem. 1999, 72:318-326.
98. Featherstone D.E., Rushton E., Rohrbough J., Liebl F., Karr J., Sheng Q., Rodesch C.K., Broadie K. An essential Drosophila glutamate receptor subunit that functions in both central neuropil and neuromuscular junction. J. Neurosci. 2005, 25:3199-3208.
99. Feng X.-P., Hayashi J., Beech R.N., Prichard R.K. Study of the nematode putative GABA type-A receptor subunits: evidence for modulation by ivermectin. J. Neurochem. 2002, 83:870-878.
100. Ferraguti F., Crepaldi L., Nicoletti F. Metabotropic glutamate 1 receptor: current concepts and perspectives. Pharmacol. Rev. 2008, 60:536-581.
101. ffrench-Constant R.H., Rocheleau T.A. Drosophila γ-aminobutyric acid receptor gene Rdl shows extensive alternative splicing. J. Neurochem. 1993, 60:2323-2326.
102. ffrench-Constant R.H., Roush R.T. Gene mapping and cross-resistance in cyclodiene insecticide-resistant Drosophila melanogaster (Mg.). Genet. Res. 1991, 57:17-21.
103. ffrench-Constant R.H., Roush R.T., Mortlock D., Dively G.P. Isolation of dieldrin resistance from field populations of Drosophila melanogaster (Diptera: Drosophilidae). J. Econ. Entomol. 1990, 83:1733-1737.
104. ffrench-Constant R.H., Mortlock D.P., Shaffer C.D., MacIntyre R.J., Roush R.T. Molecular cloning and transformation of cyclodiene resistance in Drosophila: an invertebrate γ-aminobutyric acid subtype A receptor locus. Proc. Natl. Acad. Sci. U.S.A. 1991, 88:7209-7213.
105. ffrench-Constant R.H., Rocheleau T.A., Steichen J.C., Chalmers A.E. A point mutation in a Drosophila GABA receptor confers insecticide resistance. Nature 1993, 363:449-451.
106. ffrench-Constant R.H., Steichen J.C., Rocheleau T.A., Aronstein K., Roush R.T. A single-amino acid substitution in a γ-aminobutyric acid subtype A receptor locus is associated with cyclodiene insecticide resistance in Drosophila populations. Proc. Natl. Acad. Sci. U.S.A. 1993, 90:1957-1961.
107. ffrench-Constant R.H., Steichen J.C., Brun L.O. A molecular diagnostic for endosulfan insecticide resistance in the coffee berry borer Hypothenemus hampei (Coleoptera: Scolytidae). Bull. Entomol. Res. 1994, 84:11-16.
108. Florey E. An inhibitory and an excitatory factor of mammalian central nervous system, and their action of a single sensory neuron. Arch. Int. Physiol. 1954, 62:33-53.
109. +-evoked release of acetylcholine from cockroach synaptosomes. Comp. Biochem. Physiol. C 1999, 122:283-286.
110. Gengs C., Leung H.-T., Skingsley D.R., Iovchev M.I., Yin Z., Semenov E.P., Burg M.G., Hardie R.C., Pak W.L. The target of Drosophila photoreceptor synaptic transmission is a histamine-gated chloride channel encoded by ort (hclA). J. Biol. Chem. 2002, 277:42113-42120.
111. Ghiasuddin S.M., Matsumura F. Inhibition of gamma-aminobutyric acid (GABA)-induced chloride uptake by gamma-BHC and heptachlor epoxide. Comp. Biochem. Physiol. C 1982, 73:141-144.
112. Gill S. Addendum: recent progress in insect GABA receptors. Insect Pharmacology: Channels, Receptors, Toxins and Enzymes 2010, 65-67. Elsevier Academic Press, London. L.I. Gilbert, S.S. Gill (Eds.).
113. Gisselmann G., Pusch H., Hovemann B.T., Hatt H. Two cDNAs coding for histamine-gated ion channels in D. melanogaster. Nat. Neurosci. 2002, 5:11-12.
114. Gisselmann G., Plonka J., Pusch H., Hatt H. Drosophila melanogaster GRD and LCCH3 subunits form heteromultimeric GABA-gated cation channels. Br. J. Pharmacol. 2004, 142:409-413.
115. Glendinning S.K., Buckingham S.D., Sattelle D.B., Wonnacott S., Wolstenholme A.J. Glutamate-gated chloride channels of Haemonchus contortus restore drug sensitivity to ivermectin resistant Caenorhabditis elegans. PLoS One 2011, 6:e22390.
116. Gondhalekar A.D., Scharf M.E. Mechanisms underlying fipronil resistance in a multiresistant field strain of the German cockroach (Blattodea: Blattellidae). J. Med. Entomol. 2012, 49:122-131.
117. Grolleau F., Sattelle D.B. Single channel analysis of the blocking actions of BIDN and fipronil on a Drosophila melanogaster GABA receptor (RDL) stably expressed in a Drosophila cell line. Br. J. Pharmacol. 2000, 130:1833-1842.
118. Grünewald B., Wersing A. An ionotropic GABA receptor in cultured mushroom body Kenyon cells of the honeybee and its modulation by intracellular calcium. J. Comp. Physiol. A 2008, 194:329-340.
119. Guillemaud T., Brun A., Anthony N., Sauge M.-H., Boll R., Delorme R., Fournier D., Lapchin L., Vanlerberghe-Masutti F. Incidence of insecticide resistance alleles in sexually-reproducing populations of the peach-potato aphid Myzus persicae (Hemiptera: Aphididae) from southern France. Bull. Entomol. Res. 2003, 93:289-297.
120. A channel that abolish block by picrotoxin. Receptors Channels 1995, 3:13-20.
121. Hainzl D., Casida J.E. Fipronil insecticide: novel photochemical desulfinylation with retention of neurotoxicity. Proc. Natl. Acad. Sci. U.S.A. 1996, 93:12764-12767.
122. Hamann M., Desarmenien M., Vanderheyden P., Piguet P., Feltz P. Electrophysiological study of tert-butylbicyclophosphorothionate-induced block of spontaneous chloride channels. Mol. Pharmacol. 1990, 37:578-582.
123. Hamano H., Nagata K., Fukuda N., Shimotahira H., Ju X.-L., Ozoe Y. 5-[4-(3,3-Dimethylbutoxycarbonyl)phenyl]-4-pentynoic acid and its derivatives inhibit ionotropic γ-aminobutyric acid receptors by binding to the 4'-ethynyl-4-n-propylbicycloorthobenzoate site. Bioorg. Med. Chem. 2000, 8:665-674.
124. B receptors and decreases in calcium. J. Neurobiol. 2005, 65:225-240.
125. - channels. Brain Res. 1998, 780:20-26.
126. Hansen K.K., Kristensen M., Jensen K.-M.V. Correlation of a resistance-associated Rdl mutation in the German cockroach, Blattellla germanica (L.), with persistent dieldrin resistance in two Danish field populations. Pest Manag. Sci. 2005, 61:749-753.
127. Harrison J.B., Chen H.H., Sattelle E., Barker P.J., Huskisson N.S., Rauh J.J., Bai D., Sattelle D.B. Immunocytochemical mapping of a C-terminus anti-peptide antibody to the GABA receptor subunit, RDL in the nervous system of Drosophila melanogaster. Cell Tissue Res. 1996, 284:269-278.
128. Harvey R.J., Schmitt B., Hermans-Borgmeyer I., Gundelfinger E.D., Betz H., Darlison M.G. Sequence of a Drosophila ligand-gated ion-channel polypeptide with an unusual amino-terminal extracellular domain. J. Neurochem. 1994, 62:2480-2483.
129. 2 receptors modulate supraoptic oxytocin neuronal excitability and dye coupling. J. Neurosci. 2001, 21:2974-2982.
130. Hawthorne R., Cromer B.A., Ng H.-L., Parker M.W., Lynch J.W. Molecular determinants of ginkgolide binding in the glycine receptor pore. J. Neurochem. 2006, 98:395-407.
131. Hayden W.J., Gillis W.T., Stone D.E., Broome C.R., Webster G.L. Systematics and palynology of Picrodendron: further evidence for relationship with the Oldfieldioideae (Euphorbiaceae). J. Arnold Arbor. 1984, 65:105-127.
132. Heads J.A., Hawthorne R.L., Lynagh T., Lynch J.W. Structure-activity analysis of ginkgolide binding in the glycine receptor pore. J. Neurochem. 2008, 105:1418-1427.
133. Henderson J.E., Soderlund D.M., Knipple D.C. Characterization of a putative γ-aminobutyric acid (GABA) receptor β subunit gene from Drosophila melanogaster. Biochem. Biophys. Res. Commun. 1993, 193:474-482.
134. Henderson J.E., Knipple D.C., Soderlund D.M. PCR-based homology probing reveals a family of GABA receptor-like genes in Drosophila melanogaster. Insect Biochem. Mol. Biol. 1994, 24:363-371.
135. A receptors. Mol. Neurobiol. 1998, 18:35-86.
136. Hibbs R.E., Gouaux E. Principles of activation and permeation in an anion-selective Cys-loop receptor. Nature 2011, 474:54-60.
137. Hilf R.J.C., Dutzler R. X-ray structure of a prokaryotic pentameric ligand-gated ion channel. Nature 2008, 452:375-379.
138. Hilf R.J.C., Dutzler R. Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel. Nature 2009, 457:115-118.
139. Hille B. Ionic Channels of Excitable Membranes 2001, Sinauer Associates, Sunderland. third ed.
140. Hiragaki S., Kobayashi T., Ochiai N., Toshima K., Dekeyser M.A., Matsuda K., Takeda M. A novel action of highly specific acaricide; bifenazate as a synergist for a GABA-gated chloride channel of Tetranychus urticae [Acari: Tetranychidae]. Neurotoxicology 2012, 33:307-313.
141. Hirata K., Ishida C., Eguchi Y., Sakai K., Ozoe F., Ozoe Y., Matsuda K. Role of a serine residue (S278) in the pore-facing region of the housefly L-glutamate-gated chloride channel in determining sensitivity to noncompetitive antagonists. Insect Mol. Biol. 2008, 17:341-350.
142. Hisano K., Ozoe F., Huang J., Kong X., Ozoe Y. The channel-lining 6' amino acid in the second membrane-spanning region of ionotropic GABA receptors has more profound effects on 4'-ethynyl-4-n-propylbicycloorthobenzoate binding than the 2' amino acid. Invert. Neurosci. 2007, 7:39-46.
143. Holbrook G.L., Roebuck J., Moore C.B., Waldvogel M.G., Schal C. Origin and extent of resistance to fipronil in the German cockroach, Blattella germanica (L.) (Dictyoptera: Blattellidae). J. Econ. Entomol. 2003, 96:1548-1558.
144. Höld K.M., Sirisoma N.S., Sparks S.E., Casida J.E. Metabolism and mode of action of cis- and trans-3-pinanones (the active ingredients of hyssop oil). Xenobiotica 2000, 32:251-265.
145. Höld K.M., Sirisoma N.S., Ikeda T., Narahashi T., Casida J.E. α-Thujone (the active component of absinthe): γ-aminobutyric acid type A receptor modulation and metabolic detoxification. Proc. Natl. Acad. Sci. U.S.A. 2002, 97:3826-3831.
146. Hope M., Menzies M., Kemp D. Identification of a dieldrin resistance-associated mutation in Rhipicephalus (Boophilus) microplus (Acari: Ixodidae). J. Econ. Entomol. 2010, 103:1355-1359.
147. Horoszok L., Raymond V., Sattelle D.B., Wolstenholme A.J. GLC-3: a novel fipronil and BIDN-sensitive, but picrotoxinin-insensitive, L-glutamate-gated chloride channel subunit from Caenorhabditis elegans. Br. J. Pharmacol. 2001, 132:1247-1254.
148. Hosie A.M., Baylis H.A., Buckingham S.D., Sattelle D.B. Actions of the insecticide fipronil, on dieldrin-sensitive and -resistant GABA receptors of Drosophila melanogaster. Br. J. Pharmacol 1995, 115:909-912.
149. Hosie A.M., Sattelle D.B. Allosteric modulation of an expressed homo-oligomeric GABA-gated chloride channel of Drosophila melanogaster. Br. J. Pharmacol. 1996, 117:1229-1237.
150. Hosie A.M., Sattelle D.B. Agonist pharmacology of two Drosophila GABA receptor splice variants. Br. J. Pharmacol. 1996, 119:1577-1585.
151. Hosie A.M., Ozoe Y., Koike K., Ohmoto T., Nikaido T., Sattelle D.B. Actions of picrodendrin antagonists on dieldrin-sensitive and -resistant Drosophila GABA receptors. Br. J. Pharmacol. 1996, 119:1569-1576.
152. Hosie A.M., Aronstein K., Sattelle D.B., ffrench-Constant R.H. Molecular biology of insect neuronal GABA receptors. Trends Neurosci. 1997, 20:578-583.
153. Hosie A.M., Buckingham S.D., Presnail J.K., Sattelle D.B. Alternative splicing of a Drosophila GABA receptor subunit gene identifies determinants of agonist potency. Neuroscience 2001, 102:709-714.
154. Hosie A.M., Buckingham S.D., Hamon A., Sattelle D.B. Replacement of asparagine with arginine at the extracellular end of the second transmembrane (M2) region of insect GABA receptors increases sensitivity to penicillin G. Invert. Neurosci. 2006, 6:75-79.
155. A receptors. Eur. J. Pharmacol. 2003, 464:1-8.
156. A receptors. Eur. J. Pharmacol. 2004, 494:131-138.
157. C receptor. Neuroscience 2006, 137:607-617.
158. Hue B. Functional assay for GABA receptor subtypes of a cockroach giant interneuron. Arch. Insect Biochem. Physiol. 1991, 18:147-157.
159. Hue B. A picrotoxin-resistant GABA-gated chloride channel receptor subtype in the cockroach central nervous system. Arch. Insect Biochem. Physiol. 1998, 37:231-238.
160. Hue B., Pelhate M., Chanelet J. Pre- and postsynaptic effects of taurine and GABA in the cockroach central nervous system. Can. J. Neurol. Sci. 1979, 6:243-250.
161. Ide J., Okazaki T., Ono M., Saito A., Nakagawa K., Naito S., Sato K., Tanaka K., Yoshikawa H., Ando M., Katsumi S., Matsumoto K., Toyama T., Shibano M., Abe M. Milbemycin: discovery and development. Annu. Rep. Sankyo Res. Lab. 1993, 45:1-98.
162. Ihara M., Ishida C., Okuda H., Ozoe Y., Matsuda K. Differential blocking actions of 4'-ethynyl-4-n-propylbicycloorthobenzoate (EBOB) and γ-hexachlorocyclohexane (γ-HCH) on γ-aminobutyric acid- and glutamate-induced responses of American cockroach neurons. Invert. Neurosci. 2005, 5:157-164.
163. Ikeda T., Ozoe Y., Okuyama E., Nagata K., Honda H., Shono T., Narahashi T. Anisatin modulation of the γ-aminobutyric acid receptor-channel in rat dorsal root ganglion neurons. Br. J. Pharmacol. 1999, 127:1567-1576.
164. A receptors in rat dorsal root ganglion neurons. J. Pharmacol. Exp. Ther. 2001, 296:914-921.
165. A receptor single-channel currents. Pest Manag. Sci. 2004, 60:487-492.
166. A receptor subtypes. Br. J. Pharmacol. 1994, 112:1025-1030.
167. Inoue M., Akaike N. Blockade of γ-aminobutyric acid-gated chloride current in frog sensory neurons by picrotoxin. Neurosci. Res. 1988, 5:380-394.
168. Islam R., Lynch J.W. Mechanism of action of the insecticides, lindane and fipronil, on glycine receptor chloride channels. Br. J. Pharmacol. 2012, 165:2707-2720.
169. a receptors. Pestic. Biochem. Physiol. 1997, 58:103-107.
170. A receptors. J. Biol. Chem. 2003, 278:49279-49285.
171. Jackel C., Krenz W.-D., Nagy F. Bicuculline/baclofen-insensitive GABA response in crustacean neurones in culture. J. Exp. Biol. 1994, 191:167-193.
172. Janssen D., Derst C., Rigo J.-M., Van Kerkhove E. Cys-loop ligand-gated chloride channels in dorsal unpaired median neurons of Locusta migratoria. J. Neurophysiol. 2010, 103:2587-2598.
173. Jaracz S., Nakanishi K., Jensen A.A., Strømgaard K. Ginkgolides and glycine receptors: a structure-activity relationship study. Chem. Eur. J. 2004, 10:1507-1518.
174. Jarboe C.H., Porter L.A. The preparative column chromatographic separation of picrotoxin. J. Chromatogr. 1965, 19:427-428.
175. Jarboe C.H., Porter L.A., Buckler R.T. Structural aspects of picrotoxinin action. J. Med. Chem. 1968, 11:729-731.
176. Jensen A.A., Begum N., Vogensen S.B., Knapp K.M., Gundertofte K., Dzyuba S.V., Ishii H., Nakanishi K., Kristiansen U., Strømgaard K. Probing the pharmacophore of ginkgolides as glycine receptor antagonists. J. Med. Chem. 2007, 50:1610-1617.
177. Jensen A.A., Bergmann M.L., Sander T., Balle T. Ginkgolide X is a potent antagonist of anionic Cys-loop receptors with a unique selectivity profile at glycine receptors. J. Biol. Chem. 2010, 285:10141-10153.
178. Jones A.K., Sattelle D.B. The cys-loop ligand-gated ion channel superfamily of the honeybee, Apis mellifera. Invert. Neurosci. 2006, 6:123-132.
179. Jones A.K., Sattelle D.B. The cys-loop ligand-gated ion channel gene superfamily of the red flour beetle, Tribolium castaneum. BMC Genomics 2007, 8:327.
180. Jones A.K., Buckingham S.D., Papadaki M., Yokota M., Sattelle B.M., Matsuda K., Sattelle D.B. Splice-variant- and stage-specific RNA editing of the Drosophila GABA receptor modulates agonist potency. J. Neurosci. 2009, 29:4287-4292.
181. Jones A.K., Bera A.N., Lees K., Sattelle D.B. The cys-loop ligand-gated ion channel gene superfamily of the parasitoid wasp Nasonia vitripennis. Heredity 2010, 104:247-259.
182. Ju X.-L., Ozoe Y. Bicyclophosphorothionate antagonists exhibiting selectivity for housefly GABA receptors. Pestic. Sci. 1999, 55:971-982.
183. Ju X.-L., Ozoe Y. Noncompetitive antagonist-binding sites of rat and housefly γ-aminobutyric acid receptors display different enantiospecificities for tert-butyl(isopropyl)bicyclophosphorothionate. Bioorg. Med. Chem. 2000, 8:2337-2341.
184. Ju X.-L., Hao Y.-L., Pei J.-F., Ozoe Y. Investigation of structural requirements for inhibitory activity at the rat and housefly picrotoxinin binding sites in ionotropic GABA receptors using DISCOtech and CoMFA. Chemosphere 2007, 69:864-871.
185. Ju X.-L., Fusazaki S., Hishinuma H., Qiao X., Ikeda I., Ozoe Y. Synthesis and structure-activity relationship analysis of bicyclophosphorothionate blockers with selectivity for housefly γ-aminobutyric acid receptor channels. Pest Manag. Sci. 2010, 66:1002-1010.
186. A receptor subunits contributing to the formation and affinity of the tert-butylbicyclophosphorothionate binding site. J. Neurochem. 2000, 74:1310-1316.
187. Kaku K., Matsumura F. Identification of the site of mutation within the M2 region of the GABA receptor of the cyclodiene-resistant German cockroach. Comp. Biochem. Physiol. C 1994, 108:367-376.
188. Kane N.S., Hirschberg B., Qian S., Hunt D., Thomas B., Brochu R., Ludmerer S.W., Zheng Y., Smith M., Arena J.P., Cohen C.J., Schmatz D., Warmke J., Cully D.F. Drug-resistant Drosophila indicate glutamate-gated chloride channels are targets for the antiparasitics nodulisporic acid and ivermectin. Proc. Natl. Acad. Sci. U.S.A. 2000, 97:13949-13954.
189. B receptors uncovers similarity to metabotropic glutamate receptors. Nature 1997, 386:239-246.
190. Kerkut G.A., Leake L.D., Shapira A., Cowan S., Walker R.J. The presence of glutamate in nerve-muscle perfusates of Helix, Carcinus and Periplaneta. Comp. Biochem. Physiol. 1965, 15:485-502.
191. A receptors: molecular mechanism and subunit specificity. Neuropharmacology 2007, 53:178-187.
192. Kiso M., Fujita T., Kurihara N., Uchida M., Tanaka K., Nakajima M. Structure-activity relationship of lindane analogs. Pestic. Biochem. Physiol. 1978, 8:33-43.
193. Kolaczinski J., Curtis C. Laboratory evaluation of fipronil, a phenylpyrazole insecticide, against adult Anopheles (Diptera: Culicidae) and investigation of its possible cross-resistance with dieldrin in Anopheles stephensi. Pest Manag. Sci. 2001, 57:41-45.
194. Kolodziejczyk A., Sun X., Meinertzhagen I.A., Nässel D.R. Glutamate, GABA and acetylcholine signaling components in the lamina of the Drosophila visual system. PLoS One 2008, 3:e2110.
195. Kondratskaya E.L., Lishko P.V., Chatterjee S.S., Krishtal O.A. BN52021, a platelet activating factor antagonist, is a selective blocker of glycine-gated chloride channel. Neurochem. Int. 2002, 40:647-653.
196. Korenaga S., Ito Y., Ozoe Y., Eto M. The effects of bicyclic phosphate esters on the invertebrate and vertebrate neuro-muscular junctions. Comp. Biochem. Physiol. C 1977, 57:95-100.
197. Kristensen M., Jespersen J.B., Knorr M. Cross-resistance potential of fipronil in Musca domestica. Pest Manag. Sci. 2004, 60:894-900.
198. Kristensen M., Hansen K.K., Jensen K.-M.V. Cross-resistance between dieldrin and fipronil in German cockroach (Dictyoptera: Blattellidae). J. Econ. Entomol. 2005, 98:1305-1310.
199. Krnjević K. When and why amino acids?. J. Physiol. 2010, 588:33-44.
200. Kuriyama T., Schmidt T.J., Okuyama E., Ozoe Y. Structure-activity relationships of seco-prezizaane terpenoids in γ-aminobutyric acid receptors of houseflies and rats. Bioorg. Med. Chem. 2002, 10:1873-1881.
201. Kuriyama T., Kakemoto E., Takahashi N., Imamura K., Oyama K., Suzuki E., Harimaya K., Yaguchi T., Ozoe Y. Receptor assay-guided isolation of anti-GABAergic insecticidal alkaloids from a fungal culture. J. Agric. Food Chem. 2004, 52:3884-3887.
202. Kuriyama T., Ju X.-L., Fusazaki S., Hishinuma H., Satou T., Koike K., Nikaido T., Ozoe Y. Nematocidal quassinoids and bicyclophosphorothionates: a possible common mode of action on the GABA receptor. Pestic. Biochem. Physiol. 2005, 81:176-187.
203. Kwon D.H., Yoon K.S., Clark J.M., Lee S.H. A point mutation in a glutamate-gated chloride channel confers abamectin resistance in the two-spotted spider mite, Tetranychus urticae Koch. Insect Mol. Biol. 2010, 19:583-591.
204. Lea T.J., Usherwood P.N.R. The site of action of ibotenic acid and the identification of two populations of glutamate receptors on insect muscle-fibres. Comp. Gen. Pharmacol. 1973, 4:333-350.
205. Le Corronc H., Alix P., Hue B. Differential sensitivity of two insect GABA-gated chloride channels to dieldrin, fipronil and picrotoxinin. J. Insect Physiol. 2002, 48:419-431.
206. Lee H.-J., Rocheleau T., Zhang H.-G., Jackson M.B., ffrench-Constant R.H. Expression of a Drosophila GABA receptor in a baculovirus insect cell system. FEBS Lett. 1993, 335:315-318.
207. Lee H.-J., Zhang H.-G., Jackson M.B., ffrench-Constant R.H. Binding and physiology of 4'-ethynyl-4-n-propylbicycloorthobenzoate (EBOB) in cyclodiene-resistant Drosophila. Pestic. Biochem. Physiol 1995, 51:30-37.
208. Lee D., Su H., O'Dowd D.K. GABA receptors containing Rdl subunits mediate fast inhibitory synaptic transmission in Drosophila neurons. J. Neurosci. 2003, 23:4625-4634.
209. Lees G., Calder J. Interaction of lindane isomers with chloride currents in insect membranes: steric requirements for channel modulation and block. Pestic. Biochem. Physiol. 1996, 55:40-48.
210. Le Goff G., Hamon A., Bergé J.-B., Amichot M. Resistance to fipronil in Drosophila simulans: influence of two point mutations in the RDL GABA receptor subunit. J. Neurochem. 2005, 92:1295-1305.
211. Li P., Akk G. The insecticide fipronil and its metabolite fipronil sulfone inhibit the rat α1β2γ2L GABA receptor. Br. J. Pharmacol. 2008, 155:783-794.
212. Li A., Yang Y., Wu S., Li C., Wu Y. Investigation of resistance mechanisms to fipronil in diamondback moth (Lepidoptera: Plutellidae). J. Econ. Entomol. 2006, 99:914-919.
213. Liu X., Davis R.L. The GABAergic anterior paired lateral neuron suppresses and is suppressed by olfactory learning. Nat. Neurosci. 2009, 12:53-59.
214. Liu H.-P., Lin S.-C., Lin C.-Y., Yeh S.-R., Chiang A.-S. Glutamate-gated chloride channels inhibit juvenile hormone biosynthesis in the cockroach, Diploptera punctata. Insect Biochem. Mol. Biol. 2005, 35:1260-1268.
215. A receptor RDL inhibits Drosophila olfactory associative learning. Neuron 2007, 56:1090-1102.
216. A receptor RDL suppresses the conditioned stimulus pathway for olfactory learning. J. Neurosci. 2009, 29:1573-1579.
217. Ludmerer S.W., Warren V.A., Williams B.S., Zheng Y., Hunt D.C., Ayer M.B., Wallace M.A., Chaudhary A.G., Egan M.A., Meinke P.T., Dean D.C., Garcia M.L., Cully D.F., Smith M.M. Ivermectin and nodulisporic acid receptors in Drosophila melanogaster contain both γ-aminobutyric acid-gated Rdl and glutamate-gated GluClα chloride channel subunits. Biochemistry 2002, 41:6548-6560.
218. Lummis S.C.R., McGonigle I., Ashby J.A., Dougherty D.A. Two amino acid residues contribute to a cation-π binding interaction in the binding site of an insect GABA receptor. J. Neurosci. 2011, 31:12371-12376.
219. Lyga J.W., Ali S.F., Kinne L.P., Marek F.L., Wusaty M.A., Staetz C.A., Willut J. Discovery of 3-arylpyrimidin-2,4-diones as GABA-gated chloride channel insecticides: translation from target site to field. ACS Symposium Series 948 2007, 153-166. American Chemical Society, Washington, DC. J.W. Lyga, G. Theodoridis (Eds.).
220. Lynagh T., Lynch J.W. A glycine residue essential for high ivermectin sensitivity in Cys-loop ion channel receptors. Int. J. Parasitol. 2010, 40:1477-1481.
221. MacLeod K., Laurent G. Distinct mechanisms for synchronization and temporal patterning of odor-encoding neural assemblies. Science 1996, 274:976-979.
222. Martin R.J., Pennington A.J. A patch-clamp study of effects of dihydroavermectin on Ascaris muscle. Br. J. Pharmacol. 1989, 98:747-756.
223. A receptor subunit combination. Br. J. Pharmacol. 2001, 132:205-212.
224. Matsuda K., Hosie A.M., Holyoke C.W., Rauh J.J., Sattelle D.B. Cross-resistance with dieldrin of a novel tricyclic dinitrile GABA receptor antagonist. Br. J. Pharmacol. 1999, 127:1305-1307.
225. Matsumura F., Ghiasuddin S.M. Evidence for similarities between cyclodiene type insecticides and picrotoxinin in their action mechanisms. J. Environ. Sci. Health B 1983, 18:1-14.
226. Matsumura M., Takeuchi H., Satoh M., Sanada-Morimura S., Otuka A., Watanabe T., Thanh D.V. Species-specific insecticide resistance to imidacloprid and fipronil in the rice planthoppers Nilaparvata lugens and Sogatella furcifera in Eat and South-east Asia. Pest Manag. Sci. 2008, 64:1115-1121.
227. McCarthy E.v., Wu Y., deCarvalho T., Brandt C., Gao G., Nitabach M.N. Synchronized bilateral synaptic inputs to Drosophila melanogaster neuropeptidergic rest/arousal neurons. J. Neurosci. 2011, 31:8181-8193.
228. McGonigle I., Lummis S.C.R. Molecular characterization of agonists that bind to an insect GABA receptor. Biochemistry 2010, 49:2897-2902.
229. Ménez C., Sutra J.-F., Prichard R., Lespine A. Relative neurotoxicity of ivermectin and moxidectin in Mdr1ab (-/-) mice and effects on mammalian GABA(A) channel activity. PLoS Negl. Trop. Dis. 2012, 6:e1883.
230. B receptors from Drosophila. Eur. J. Neurosci. 2001, 13:477-486.
231. Millar N.S., Buckingham S.D., Sattelle D.B. Stable expression of a functional homo-oligomeric Drosophila GABA receptor in a Drosophila cell line. Proc. R. Soc. Lond. B 1994, 258:307-314.
232. Miller P.S., Smart T.G. Binding, activation and modulation of Cys-loop receptors. Trends Pharmacol. Sci. 2010, 31:161-174.
233. Miller T.A., Maynard M., Kennedy J.M. Structure and insecticidal activity of picrotoxinin analogs. Pestic. Biochem. Physiol. 1979, 10:128-136.
234. Miyazaki M., Matsumura F., Beeman R.W. DNA sequence and site of mutation of the GABA receptor of cyclodiene-resistant red flour beetle, Tribolium castaneum. Comp. Biochem. Physiol. B Biochem. Mol. Biol. 1995, 111:399-406.
235. Miyazawa A., Fujiyoshi Y., Unwin N. Structure and gating mechanism of the acetylcholine receptor pore. Nature 2003, 423:949-955.
236. Mohan M., Gujar G.T. Local variation in susceptibility of the diamondback moth, Plutella xylostella (Linnaeus) to insecticides and role of detoxification enzymes. Crop Prot. 2003, 22:495-504.
237. Moore E.L., Haspel G., Libersat F., Adams M.E. Parasitoid wasp sting: a cocktail of GABA, taurine and β-alanine opens chloride channels for central synaptic block and transient paralysis of a cockroach host. J. Neurobiol. 2006, 66:811-820.
238. Mullins L.J. Structure-toxicity in hexachlorocyclohexane isomers. Science 1955, 122:118-119.
239. Murillo L., Hamon A., Es-Salah-Lamoureux Z., Itier V., Quinchard S., Lapied B. Inhibition of protein kinase C decreases sensitivity of GABA receptor subtype to fipronil insecticide in insect neurosecretory cells. Neurotoxicology 2011, 32:828-835.
240. Murphy V.F., Wann K.T. The action of GABA receptor agonists and antagonists on muscle membrane conductance in Schistocerca gregaria. Br. J. Pharmacol. 1988, 95:713-722.
241. Nagata K., Narahashi T. Dual action of the cyclodiene insecticide dieldrin on the γ-aminobutyric acid receptor-chloride channel complex of rat dorsal root ganglion neurons. J. Pharmacol. Exp. Ther. 1994, 269:164-171.
242. Nagata K., Narahashi T. Differential effects of hexachlorocyclohexane isomers on the GABA receptor-chloride channel complex in rat dorsal root ganglion neurons. Brain Res. 1995, 704:85-91.
243. A receptor-channel subunits expressed in human embryonic kidney cells. Brain Res. 1994, 645:19-26.
244. Nagata K., Huang C.-S., Hamilton B.J., Carter D.B., Narahashi T. Differential effects of hexachlorocyclohexane isomers on the GABA receptor subunits expressed in human embryonic kidney cell line. Brain Res. 1996, 738:131-137.
245. Nakao T., Naoi A., Kawahara N., Hirase K. Mutation of the GABA receptor associated with fipronil resistance in the whitebacked planthopper, Sogatella furcifera. Pestic. Biochem. Physiol. 2010, 97:262-266.
246. Nakao T., Kawase A., Kinoshita A., Abe R., Hama M., Kawahara N., Hirase K. The A2'N mutation of the RDL γ-aminobutyric acid receptor conferring fipronil resistance in Laodelphax striatellus (Hemiptera: Delphacidae). J. Econ. Entomol. 2011, 104:646-652.
247. Nakao T., Hama M., Kawahara N., Hirase K. Fipronil resistance in Sogatella furcifera: molecular cloning and functional expression of wild-type and mutant RDL GABA receptor subunits. J. Pestic. Sci. 2012, 37:37-44.
248. Nakao T., Naoi A., Hama M., Kawahara N., Hirase K. Concentration-dependent effects of GABA on insensitivity to fipronil in the A2'S mutant RDL GABA receptor from fipronil-resistant Oulema oryzae (Coleoptera: Chrysomelidae). J. Econ. Entomol 2012, 105:1781-1788.
249. Narahashi T., Zhao X., Ikeda T., Salgado V.L., Yeh J.Z. Glutamate-activated chloride channels: unique fipronil targets present in insects but not in mammals. Pestic. Biochem. Physiol. 2010, 97:149-152.
250. Narusuye K., Nakao T., Abe R., Nagatomi Y., Hirase K., Ozoe Y. Molecular cloning of a GABA receptor subunit from Laodelphax striatella (Fallén) and patch clamp analysis of the homo-oligomeric receptors expressed in a Drosophila cell line. Insect Mol. Biol. 2007, 16:723-733.
251. m-shift primers. Pestic. Biochem. Physiol. 2010, 97:204-208.
252. Newland C.F., Cull-Candy S.G. On the mechanism of action of picrotoxin on GABA receptor channels in dissociated sympathetic neurones of the rat. J. Physiol. 1992, 447:191-213.
253. Niswener C.M., Conn P.J. Metabotropic glutamate receptors: physiology, pharmacology, and disease. Annu. Rev. Pharmacol. Toxicol. 2010, 50:295-322.
254. Njue A.I., Hayashi J., Kinne L., Feng X.-P., Prichard R.K. Mutations in the extracellular domains of glutamate-gated chloride channel α3 and β subunits from ivermectin-resistant Cooperia oncophora affect agonist sensitivity. J. Neurochem. 2004, 89:1137-1147.
255. Nury H., Van Renterghem C., Weng Y., Tran A., Baaden M., Dufresne V., Changeux J.-P., Sonner J.M., Delarue M., Corringer P.-J. X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel. Nature 2011, 469:428-431.
256. Okada R., Awasaki T., Ito K. Gamma-aminobutyric acid (GABA)-mediated neural connections in the Drosophila antennal lobe. J. Comp. Neurol. 2009, 514:74-91.
257. A receptors: classification on the basis of subunit composition, pharmacology, and function. Update. Pharmacol. Rev. 2008, 60:243-260.
258. Ondeyka J.G., Helms G.L., Hensens O.D., Goetz M.A., Zink D.L., Tsipouras A., Shoop W.L., Slayton L., Dombrowski A.W., Polishook J.D., Ostlind D.A., Tsou N.N., Ball R.G., Singh S.B. Nodulisporic acid A, a novel and potent insecticide from a Nodulisporium Sp. Isolation, structure determination, and chemical transformations. J. Am. Chem. Soc. 1997, 119:8809-8816.
259. A receptor spontaneous gating, agonist activation and desensitization. J. Physiol. 2012, 590:163-178.
260. Otsuka M., Iversen L.L., Hall Z.W., Kravitz E.A. Release of gamma-aminobutyric acid from inhibitory nerves of lobster. Proc. Natl. Acad. Sci. U.S.A. 1966, 56:1110-1115.
261. Otsuka M., Kravitz E.A., Potter D.D. Physiological and chemical architecture of a lobster ganglion with particular reference to gamma-aminobutyrate and glutamate. J. Neurophysiol. 1967, 30:725-752.
262. Ozoe Y., Akamatsu M. Non-competitive GABA antagonists: probing the mechanisms of their selectivity for insect versus mammalian receptors. Pest Manag. Sci. 2001, 57:923-931.
263. Ozoe Y., Eto M. Bridged bicyclic organophosphorus compounds as a probe for toxicological study on GABA synapse. Membrane Receptors and Enzymes as Targets of Insecticidal Action 1986, 75-105. Plenum Press, New York. J.M. Clark, F. Matsumura (Eds.).
264. Ozoe Y., Matsumura F. Structural requirements for bridged bicyclic compounds acting on picrotoxinin receptor. J. Agric. Food Chem. 1986, 34:126-134.
265. Ozoe Y., Mochida K., Nakamura T., Shimizu A., Eto M. Toxicity of bicyclic phosphate GABA antagonists to the housefly, Musca domestica L. J. Pestic. Sci. 1983, 8:601-605.
266. Ozoe Y., Mochida K., Nakamura T., Yoyama A., Matsumura F. Actions of benzodiazepines on the housefly: binding to thorax/abdomen extracts and biological effects. Comp. Biochem. Physiol. C 1987, 87:187-191.
267. 3H]Ro 5-4864 responding to GABA receptor ligands. Comp. Biochem. Physiol. C 1989, 93:193-199.
268. Ozoe Y., Sawada Y., Mochida K., Nakamura T., Matsumura F. Structure-activity relationships in a new series of insecticidally active dioxatricycloalkenes derived by structural comparison of the GABA antagonists bicycloorthocarboxylates and endosulfan. J. Agric. Food Chem. 1990, 38:1264-1268.
269. Ozoe Y., Kuwano E., Eto M. Potency of isomers of 8-isopropyl-6-oxabicyclo[3.2.1]octan-7-one at the picrotoxinin binding site in the GABA-gated chloride channel in rat brain. Biosci. Biotechol. Biochem. 1993, 57:504-505.
270. A receptors. J. Agric. Food Chem. 1993, 41:2135-2141.
271. Ozoe Y., Akamatsu M., Higata T., Ikeda I., Mochida K., Koike K., Ohmoto T., Nikaido T. Picrodendrin and related terpenoid antagonists reveal structural differences between ionotropic GABA receptors of mammals and insects. Bioorg. Med. Chem. 1998, 6:481-492.
272. Ozoe Y., Niina K., Matsumoto K., Ikeda I., Mochida K., Ogawa C., Matsuno A., Miki M., Yanagi K. Actions of cyclic esters, S-esters, and amides of phenyl- and phenylthiophosphonic acids on mammalian and insect GABA-gated chloride channels. Bioorg. Med. Chem. 1998, 6:73-83.
273. Ozoe Y., Yagi K., Nakamura M., Akamatsu M., Miyake T., Matsumura F. Fipronil-related heterocyclic compounds: structure-activity relationships for interaction with γ-aminobutyric acid- and voltage-gated ion channels and insecticidal action. Pestic. Biochem. Physiol. 2000, 66:92-104.
274. Ozoe Y., Ishikawa S., Tomiyama S., Ozoe F., Kozaki T., Scott J.G. Antagonism of the GABA receptor of dieldrin-resistant houseflies by fipronil and its analogues. ACS Symposium Series 948 2007, 39-50. American Chemical Society, Washington, DC. J.W. Lyga, G. Theodoridis (Eds.).
275. Ozoe Y., Takeda M., Matsuda K. γ-Aminobutyric acid receptors: a rationale for developing selective insect pest control chemicals. Biorational Control of Arthropod Pests 2009, 131-162. Springer, Heidelberg. I. Ishaaya, A.R. Horowitz (Eds.).
276. Ozoe Y., Asahi M., Ozoe F., Nakahira K., Mita T. The antiparasitic isoxazoline A1443 is a potent blocker of insect ligand-gated chloride channels. Biochem. Biophys. Res. Commun. 2010, 391:744-749.
277. Palmer C.J., Casida J.E. Insecticidal 1,3-dithianes and 1,3-dithiane 1,1-dioxides. J. Agric. Food Chem. 1992, 40:492-496.
278. Palmer C.J., Cole L.M., Larkin J.P., Smith I.H., Casida J.E. 1-(4-Ethynylphenyl)-4-substituted-2,6,7-trioxabicyclo[2.2.2]octanes; effect of 4-substituent on toxicity to houseflies and mice and potency at the GABA-gated chloride channel. J. Agric. Food Chem. 1991, 39:1329-1334.
279. Parisky K.M., Agosto J., Pulver S.R., Shang Y., Kuklin E., Hodge J.J.L., Kang K., Liu X., Garrity P.A., Rosbash M., Griffith L.C. PDF cells are a GABA-responsive wake-promoting component of the Drosophila sleep circuit. Neuron 2008, 60:672-682.
280. Perret P., Sarda X., Wolff M., Wu T.-T., Bushey D., Goeldner M. Interaction of non-competitive blockers within the γ-aminobutyric acid type A chloride channel using chemically reactive probes as chemical sensors for cysteine mutants. J. Biol. Chem. 1999, 274:25350-25354.
281. Pirri J.K., McPherson A.D., Donnelly J.L., Francis M.M., Alkema M.J. A tyramine-gated chloride channel coordinates distinct motor programs of a Caenorhabditis elegans escape response. Neuron 2009, 62:526-538.
282. Porter L.A. Picrotoxinin and related substances. Chem. Rev. 1967, 67:441-464.
283. Pribilla I., Takagi T., Langosch D., Bormann J., Betz H. The atypical M2 segment of the beta subunit confers picrotoxinin resistance to inhibitory glycine receptor channels. EMBO J. 1992, 11:4305-4311.
284. A receptors and a homo-oligomeric GABA receptor from Drosophila melanogaster. Br. J. Pharmacol. 2003, 140:1363-1372.
285. Pulman D.A., Smith I.H., Larkin J.P., Casida J.E. Heterocyclic insecticides acting at the GABA-gated chloride channel: 5-aryl-2-arylpyrimidines and -1,3-thiazines. Pestic. Sci. 1996, 46:237-245.
286. Putrenko I., Zakikhani M., Dent J.A. A family of acetylcholine-gated chloride channel subunits in Caenorhabditis elegans. J. Biol. Chem. 2005, 280:6392-6398.
287. Raghu S.V., Joesch M., Borst A., Reiff D.F. Synaptic organization of lobula plate tangential cells in Drosophila: γ-aminobutyric acid receptors and chemical release sites. J. Comp. Neurol. 2007, 502:598-610.
288. Rahman M.M., Akiyoshi Y., Furutani S., Matsuda K., Furuta K., Ikeda I., Ozoe Y. Competitive antagonism of insect GABA receptors by iminopyridazine derivatives of GABA. Bioorg. Med. Chem. 2012, 20:5957-5964.
289. Ranganathan R., Cannon S.C., Horvitz H.R. Mod-1 is a serotonin-gated chloride channel that modulates locomotory behaviour in C. elegans. Nature 2000, 408:470-475.
290. Rao V.T.S., Siddiqui S.Z., Prichard R.K., Forrester S.G. A dopamine-gated ion channel (HcGGR3*) from Haemonchus contortus is expressed in the cervical papillae and is associated with macrocyclic lactone resistance. Mol. Biochem. Parasitol. 2009, 166:54-61.
291. Rao V.T.S., Accardi M.V., Siddiqui S.Z., Beech R.N., Prichard R.K., Forrester S.G. Characterization of a tyramine-gated chloride channel from Haemonchus contortus. Mol. Biochem. Parasitol. 2010, 173:64-68.
292. Ratra G.S., Casida J.E. GABA receptor subunit composition relative to insecticide potency and selectivity. Toxicol. Lett. 2001, 122:215-222.
293. A receptor β3 subunit in insecticide toxicity. Toxicol. Appl. Pharmacol. 2001, 172:233-240.
294. 3H]-BIDN, a novel bicyclic dinitrile radioligand for GABA-gated chloride channels of insects and vertebrates. Br. J. Pharmacol. 1997, 121:1496-1505.
295. Raymond V., Sattelle D.B. Novel animal-health drug targets from ligand-gated chloride channels. Nat. Rev. Drug Discov. 2002, 1:427-436.
296. Raymond V., Sattelle D.B., Lapied B. Co-existence in DUM neurones of two GluCl channels that differ in their picrotoxin sensitivity. Neuroreport 2000, 11:2695-2701.
297. Raymond-Delpech V., Matsuda K., Sattelle B.M., Rauh J.J., Sattelle D.B. Ion channels: molecular targets of neuroactive insecticides. Invert. Neurosci. 2005, 5:119-133.
298. Ren Q., Li H., Wu Y., Ren J., Guo A. A GABAergic inhibitory neural circuit regulates visual reversal learning in Drosophila. J. Neurosci. 2012, 32:11524-11528.
299. Ringstad N., Abe N., Horvitz R. Ligand-gated chloride channels are receptors for biogenic amines in C. elegans. Science 2009, 325:96-100.
300. Robbins J. The excitation and inhibition of crustacean muscle by amino acids. J. Physiol. 1959, 148:39-50.
301. Roberts E., Frankel S. γ-Aminobutyric acid in brain: its formation from glutamic acid. J. Biol. Chem. 1950, 187:55-63.
302. Rugg D. Addendum: the insecticidal macrocyclic lactones. Insect Pharmacology: Channels, Receptors, Toxins and Enzymes 2010, 97-99. Elsevier Academic Press, London. L.I. Gilbert, S.S. Gill (Eds.).
303. Rugg D., Buckingham S.D., Sattelle D.B., Jansson R.K. The insecticidal macrocyclic lactones. Insect Pharmacology: Channels, Receptors, Toxins and Enzymes 2010, 69-96. Elsevier Academic Press, London. L.I. Gilbert, S.S. Gill (Eds.).
304. A receptor-operated chloride current. Neuroreport 1994, 5:2569-2572.
305. Sammelson R.E., Caboni P., Durkin K.A., Casida J.E. GABA receptor antagonists and insecticides: common structural features of 4-alkyl-1-phenylpyrazoles and 4-alkyl-1-phenyltrioxabicyclooctanes. Bioorg. Med. Chem. 2004, 12:3345-3355.
306. Sanada-Morimura S., Sakumoto S., Ohtsu R., Otuka A., Huang S.-H., Thanh D.V., Matsumura M. Current status of insecticide resistance in the small brown planthopper, Laodelphax striatellus, in Japan, Taiwan, and Vietnam. Appl. Entmol. Zool. 2011, 46:65-73.
307. Satoh H., Daido H., Nakamura T. Preliminary analysis of the GABA-induced current in cultured CNS neurons of the cutworm moth, Spodoptera litura. Neurosci. Lett. 2005, 381:125-130.
308. Sattelle D.B. GABA receptors of insects. Adv. Insect Physiol. 1990, 22:1-113.
309. Sattelle D.B. Receptors for L-glutamate and GABA in the nervous system of an insect (Periplaneta americana). Comp. Biochem. Physiol. C 1992, 103:429-438.
310. Sattelle D.B., Pinnock R.D., Wafford K.A., David J.A. GABA receptors on the cell-body membrane of an identified insect motor neuron. Proc. R. Soc. Lond. B Biol. Sci. 1988, 232:443-456.
311. Sattelle D.B., Lummis S.C.R., Wong J.F.H., Rauh J.J. Pharmacology of insect GABA receptors. Neurochem. Res. 1991, 16:363-374.
312. Sattelle D.B., Harrison J.B., Chen H.H., Bai D., Takeda M. Immunocytochemical localization of putative γ-aminobutyric acid receptor subunits in the head ganglia of Periplaneta americana using an anti-RDL C-terminal antibody. Neurosci. Lett. 2000, 289:197-200.
313. - channels in the larval nervous system of the moth Manduca sexta. Invert. Neurosci. 2003, 5:37-43.
314. Sayyed A.H., Wright D.J. Fipronil resistance in the diamondback moth (Lepidoptera: Plutellidae): inheritance and number of genes involved. J. Econ. Entomol. 2004, 97:2043-2050.
315. Schmidt T.J., Gurrath M., Ozoe Y. Structure-activity relationships of seco-prezizaane and picrotoxane/picrodendrane terpenoids by Quasar receptor-surface modeling. Bioorg. Med. Chem. 2004, 12:4159-4167.
316. Schnee M.E., Rauh J.J., Buckingham S.D., Sattelle D.B. Pharmacology of skeletal muscle GABA-gated chloride channels in the cockroach Periplaneta americana. J. Exp. Biol. 1997, 200:2947-2955.
317. A receptor shows a ligand-gated receptor super-family. Nature 1987, 328:221-227.
318. Schuske K., Beg A.A., Jorgensen E.M. The GABA nervous system in C. elegans. Trends Neurosci. 2004, 27:407-414.
319. Scott R.H., Duce I.R. Pharmacology of GABA receptors on skeletal muscle fibres of the locust (Schistocerca gregaria). Comp. Biochem. Physiol. C 1987, 86:305-311.
320. Scott J.G., Wen Z. Toxicity of fipronil to susceptible and resistant strains of German cockroaches (Dictyoptera: Blattellidae) and house flies (Diptera: Muscidae). J. Econ. Entomol. 1997, 90:1152-1156.
321. Semenov E.P., Pak W.L. Diversification of Drosophila chloride channel gene by multiple posttranslational mRNA modifications. J. Neurochem. 1999, 72:66-72.
322. Shan Q., Haddrill J.L., Lynch J.W. A single β subunit M2 domain residue controls the picrotoxin sensitivity of αβ heteromeric glycine receptor chloride channels. J. Neurochem. 2001, 76:1109-1120.
323. Shang Q.-L., Liang P., Gao X.-W. Cloning, developmental and tissue-specific expression of γ-aminobutyric acid (GABA) receptor alpha2 subunit gene in Spodoptera exigua (Hübner). Pestic. Biochem. Physiol. 2009, 93:1-7.
324. Shi X., Liang P., Song D., Yang W., Gao X. Quantification of γ-aminobutyric acid in the heads of houseflies (Musca domestica) and diamondback moths (Plutella xylostella (L.)), using capillary electrophoresis with laser-induced fluorescence detection. J. Sep. Sci. 2012, 35:548-555.
325. Shimotahira H., Fusazaki S., Ikeda I., Ozoe Y. A photoreactive probe that differentiates the binding sites of noncompetitive GABA receptor antagonists. Bioorg. Med. Chem. Lett. 2011, 21:1598-1600.
326. Shoop W.L., Mrozik H., Fisher M.H. Structure and activity of avermectins and milbemycins in animal health. Vet. Parasitol. 1995, 59:139-156.
327. Shotkoski F., Lee H.-J., Zhang H.-G., Jackson M.B., ffrench-Constant R.H. Functional expression of insecticide-resistant GABA receptors from the mosquito Aedes aegypti. Insect Mol. Biol. 1994, 3:283-287.
328. A receptor subtypes. Pharmacol. Rev. 1995, 47:181-234.
329. 1a on chick neuronal γ-aminobutyrate receptor channels expressed in Xenopus oocytes. Mol. Pharmacol. 1987, 32:749-752.
330. Silberberg S.D., Li M., Swartz K.J. Ivermectin interaction with transmembrane helices reveals widespread rearrangements during opening of P2X receptor channels. Neuron 2007, 54:263-274.
331. Smart T.G., Constanti A. Studies on the mechanism of action of picrotoxinin and other convulsants at the crustacean muscle GABA receptor. Proc. R. Soc. Lond. B Biol. Sci. 1986, 227:191-216.
332. Smith M.M., Warren V.A., Thomas B.S., Brochu R.M., Ertel E.A., Rohrer S., Schaeffer J., Schmatz D., Petuch B.R., Tang Y.S., Meinke P.T., Kaczorowski G.J., Cohen C.J. Nodulisporic acid opens insect glutamate-gated chloride channels: identification of a new high affinity modulator. Biochemistry 2000, 39:5543-5554.
333. Soloway S.B. Correlation between biological activity and molecular structure of the cyclodiene insecticides. Advances in Pest Control Research 1965, vol. VI:85-126. Interscience Publishers, New York. R.L. Metcalf (Ed.).
334. A receptor complex reveals that it may act via the picrotoxin site. J. Pharmacol. Exp. Ther. 1997, 282:827-833.
335. 35S]t-Butylbicyclophosphorothionate binds with high affinity to brain-specific sites coupled to γ-aminobutyric acid-A and ion recognition sites. Mol. Pharmacol. 1983, 23:326-336.
336. Stilwell G.E., ffrench-Constant R.H. Transcriptional analysis of the Drosophila GABA receptor gene Resistance to dieldrin. J. Neurobiol. 1998, 36:468-484.
337. Strambi C., Cayre M., Sattelle D.B., Augier R., Charpin P., Strambi A. Immunocytochemical mapping of an RDL-like GABA receptor subunit and of GABA in brain structures related to learning and memory in the cricket Acheta domesticus. Learn. Mem. 1998, 5:78-89.
338. Su H., O'Dowd D.K. Fast synaptic currents in Drosophila mushroom body Kenyon cells are mediated by α-bungarotoxin-sensitive nicotinic acetylcholine receptors and picrotoxin-sensitive GABA receptors. J. Neurosci. 2003, 23:9246-9253.
339. Sudhakaran I.P., Holohan E.E., Osman S., Rodrigues V., VijayRaghavan K., Ramaswami M. Plasticity of recurrent inhibition in the Drosophila antennal lobe. J. Neurosci. 2012, 32:7225-7231.
340. Takeuchi A., Takeuchi N. A study of the action of picrotoxin on the inhibitory neuromuscular junction of the crayfish. J. Physiol. 1969, 205:377-391.
341. 1a on the leg muscles and the nervous system of the American cockroach. Pestic. Biochem. Physiol. 1985, 24:124-135.
342. Tanaka K., Scott J.G., Matsumura F. Picrotoxinin receptor in the central nervous system of the American cockroach: its role in the action of cyclodiene-type insecticides. Pestic. Biochem. Physiol. 1984, 22:117-127.
343. Tandon R., LePage K.T., Kaplan R.M. Cloning and characterization of genes encoding α and β subunits of glutamate-gated chloride channel protein in Cylicocyclus nassatus. Mol. Biochem. Parasitol. 2006, 150:46-55.
344. Tantely M.L., Tortosa P., Alout H., Berticat C., Berthomieu A., Rutee A., Dehecq J.-S., Makoundou P., Labbé P., Pasteur N., Weill M. Insecticide resistance in Culex pipiens quinquefasciatus and Aedes albopictus mosquitoes from La Réunion Island. Insect Biochem. Mol. Biol. 2010, 40:317-324.
345. Thompson S.M., Gähwiler B.H. Comparison of the actions of baclofen at pre- and postsynaptic receptors in the rat hippocampus in vitro. J. Physiol. 1992, 451:329-345.
346. Thompson M., Steichen J.C., ffrench-Constant R.H. Conservation of cyclodiene insecticide resistance-associated mutations in insects. Insect Mol. Biol. 1993, 2:149-154.
347. Thompson M., Shotkoski F., ffrench-Constant R. Cloning and sequencing of the cyclodiene insecticide resistance gene from the yellow fever mosquito Aedes aegypti. FEBS Lett. 1993, 325:187-190.
348. 3 receptor. Mol. Pharmacol. 2011, 80:183-190.
349. 3 receptor at a location that overlaps the picrotoxin binding site. Neuropharmacology 2011, 60:488-495.
350. Thompson A.J., McGonigle I., Duke R., Johnston G.A.R., Lummis S.C.R. A single amino acid determines the toxicity of Ginkgo biloba extracts. FASEB J. 2012, 26:1884-1891.
351. Tong F., Coats J.R. Quantitative structure-activity relationships of monoterpenoid binding activities to the housefly GABA receptor. Pest Manag. Sci. 2012, 68:1122-1129.
352. Traynelis S.F., Wollmuth L.P., McBain C.J., Menniti F.S., Vance K.M., Ogden K.K., Hansen K.B., Yuan H., Myers S.J., Dingledine R. Glutamate receptor ion channels: structure, regulation, and function. Pharmacol. Rev. 2010, 62:405-496.
353. Udenfriend S. Identification of γ-aminobutyric acid in brain by the isotope derivative method. J. Biol. Chem. 1950, 187:65-69.
354. Unwin N. Refined structure of the nicotinic acetylcholine receptor at 4 å resolution. J. Mol. Biol. 2005, 346:967-989.
355. Usherwood P.N.R. Insect glutamate receptors. Adv. Insect Physiol. 1994, 24:309-341.
356. Usherwood P.N.R., Grundfest H. Peripheral inhibition in skeletal muscle of insects. J. Neurophysiol. 1965, 28:497-518.
357. - current in acutely dissociated rat hippocampal CA1 neurons. Brain Res. 2001, 889:174-180.
358. A and glycine-gated chloride channels in primary cultures of cerebellar granule cells. Neuroscience 2003, 117:397-403.
359. Van Renterghem C., Bilbe G., Moss S., Smart T.G., Constanti A., Brown D.A., Barnard E.A. GABA receptors induced in Xenopus oocytes by chick brain mRNA: evaluation of TBPS as a use-dependent channel-blocker. Brain Res. 1987, 388:21-31.
360. Vassilatis D.K., Arena J.P., Plasterk R.H.A., Wilkinson H.A., Schaeffer J.M., Cully D.F., Van der Ploeg L.H.T. Genetic and biochemical evidence for a novel avermectin-sensitive chloride channel in Caenorhabditis elegans. Isolation and characterization. J. Biol. Chem. 1997, 272:33167-33174.
361. Vassilatis D.K., Elliston K.O., Paress P.S., Hamelin M., Arena J.P., Schaeffer J.M., Van der Ploeg L.H.T., Cully D.F. Evolutionary relationship of the ligand-gated ion channels and the avermectin-sensitive, glutamate-gated chloride channels. J. Mol. Evol. 1997, 44:501-508.
362. BR2 receptor subunits. J. Comp. Neurol. 2004, 470:339-356.
363. Waliwitiya R., Belton P., Nicholson R.A., Lowenberger C.A. Effects of the essential oil constituent thymol and other neuroactive chemicals on flight motor activity and wing beat frequency in the blowfly Phaenicia sericata. Pest Manag. Sci. 2010, 66:277-289.
364. Wang P., Slaughter M.M. Effects of GABA receptor antagonists on retinal glycine receptors and on homomeric glycine receptor alpha subunits. J. Neurophysiol. 2005, 93:3120-3126.
365. Washio H. Effects of putative neurotransmitters on dorsal unpaired median neurons of cockroach (Periplaneta americana) thoracic ganglia. J. Insect Physiol. 1994, 40:841-847.
366. Watanabe T., Arisawa M., Narusuye K., Alam M.S., Yamamoto K., Mitomi M., Ozoe Y., Nishida A. Alantrypinone and its derivatives: synthesis and antagonist activity toward insect GABA receptors. Bioorg. Med. Chem. 2009, 17:94-110.
367. A receptor with the intravenous agent, propofol. Eur. J. Pharmacol. 2008, 590:120-126.
368. Wen Z., Scott J.G. Genetic and biochemical mechanisms limiting fipronil toxicity in the LPR strain of house fly, Musca domestica. Pestic. Sci. 1999, 55:988-992.
369. Wilson R.I., Laurent G. Role of GABAergic inhibition in shaping odor-evoked spatiotemporal patterns in the Drosophila antennal lobe. J. Neurosci 2005, 25:9069-9079.
370. Witte I., Kreienkamp H.-J., Gewecke M., Roeder R. Putative histamine-gated chloride channel subunits of the insect visual system and thoracic ganglion. J. Neurochem. 2002, 83:504-514.
371. Wolff M.A., Wingate V.P.M. Characterization and comparative pharmacological studies of a functional γ-aminobutyric acid (GABA) receptor cloned from the tobacco budworm, Heliothis virescens (Noctuidae:Lepidoptera). Invert. Neurosci. 1998, 3:305-315.
372. Wolstenholme A.J., Rogers A.T. Glutamate-gated chloride channels and the mode of action of the avermectin/milbemycin anthelmintics. Parasitology 2005, 131:S85-S95.
373. Wondji C.S., Davire R.K., Tukur Z., Irving H., Djouaka R., Morgan J.C. Identification and distribution of a GABA receptor mutation conferring dieldrin resistance in the malaria vector Anopheles funestus in Africa. Insect Biochem. Mol. Biol. 2011, 41:484-491.
374. Wu Y., Ren Q., Li H., Guo A. The GABAergic anterior paired lateral neurons facilitate olfactory reversal learning in Drosophila. Learn. Mem. 2012, 19:478-486.
375. Xu H. Identification of major phylogenetic branches of inhibitory ligand-gated channel receptors. J. Mol. Evol. 1998, 47:323-333.
376. A receptor channel-lining residues probed in cysteine mutants. Biophys. J. 1995, 69:1858-1867.
377. A receptors. Neurotoxicology 2003, 24:817-824.
378. Yamaguchi M., Sawa Y., Matsuda K., Ozoe F., Ozoe Y. Amino acid residues of both the extracellular and transmembrane domains influence binding of the antiparasitic agent milbemycin to Haemonchus contortus AVR-14B glutamate-gated chloride channels. Biochem. Biophys. Res. Commun. 2012, 419:562-566.
379. Yang Z., Cromer B.A., Harvey R.J., Parker M.W., Lynch J.W. A proposed structural basis for picrotoxinin and picrotin binding in the glycine receptor pore. J. Neurochem. 2007, 103:580-589.
380. Yoon K.-W., Covey D.F., Rothman S.M. Multiple mechanisms of picrotoxin block of GABA-induced currents in rat hippocampal neurons. J. Physiol. 1993, 464:423-439.
381. Yoon K.-W., Wotring V.E., Fuse T. Multiple picrotoxinin effect on glycine channels in rat hippocampal neurons. Neuroscience 1998, 87:807-815.
382. Yu L.-L., Cui Y.-J., Lang G.-J., Zhang M.-Y., Zhang C.-X. The ionotropic γ-aminobutyric acid receptor gene family of the silkworm, Bombyx mori. Genome 2010, 53:688-697.
383. Yuan G., Gao W., Yang Y., Wu Y. Molecular cloning, genomic structure, and genetic mapping of two Rdl-orthologous genes of GABA receptors in the diamondback moth, Plutella xylostella. Arch. Insect Biochem. Physiol. 2010, 74:81-90.
384. Zhang H.-G., ffrench-Constant R.H., Jackson M.B. A unique amino acid of the Drosophila GABA receptor with influence on drug sensitivity by two mechanisms. J. Physiol. 1994, 479:65-75.
385. Zhang H.-G., Lee H.-J., Rocheleau T., ffrench-Constant R.H., Jackson M.B. Subunit composition determines picrotoxin and bicuculline sensitivity of Drosophila γ-aminobutyric acid receptors. Mol. Pharmacol. 1995, 48:835-840.
386. C receptors: a comparison of native versus recombinant receptors. Trends Pharmacol. Sci. 2001, 22:121-132.
387. Zhang J., Xue F., Chang Y. Agonist- and antagonist-induced conformational changes of loop F and their contributions to the ρ1 GABA receptor function. J. Physiol. 2009, 587:139-153.
388. Zhao X., Salgado V.L. The role of GABA and glutamate receptors in susceptibility and resistance to chloride channel blocker insecticides. Pestic. Biochem. Physiol. 2010, 97:153-160.
389. Zhao X., Salgado V.L., Yeh J.Z., Narahashi T. Differential actions of fipronil and dieldrin insecticides on GABA-gated chloride channels in cockroach neurons. J. Pharmacol. Exp. Ther. 2003, 306:914-924.
390. A receptor antagonist in rat brain. Neurosci. Lett. 2003, 337:33-36.
391. Zhao X., Salgado V.L., Yeh J.Z., Narahashi T. Kinetic and pharmacological characterization of desensitizing and non-desensitizing glutamate-gated chloride channels in cockroach neurons. Neurotoxicology 2004, 25:967-980.
392. Zhao X., Yeh J.Z., Salgado V.L., Narahashi T. Fipronil is a potent open channel blocker of glutamate-activated chloride channels in cockroach neurons. J. Pharmacol. Exp. Ther. 2004, 310:192-201.
393. Zhao Q., Li Y., Xiong L., Wang Q. Design, synthesis and insecticidal activity of novel phenylpyrazoles containing a 2,2,2-trichloro-1-alkoxyethyl moiety. J. Agric. Food Chem. 2010, 58:4992-4998.
394. Zheng Y., Hirschberg B., Yuan J., Wang A.P., Hunt D.C., Ludmerer S.W., Schmatz D.M., Cully D.F. Identification of two novel Drosophila melanogaster histamine-gated chloride channel subunits expressed in the eye. J. Biol. Chem. 2002, 277:2000-2005.
395. Zhorov B.S., Bregestovski P.D. Chloride channels of glycine and GABA receptors with blockers: Monte Carlo minimization and structure-activity relationships. Biophys. J. 2000, 78:1786-1803.
396. Zhou X.-M., Wu Q.-J., Zhang Y.-J., Bai L.-Y., Huang X.-Y. Cloning and characterization of a GABA receptor from Plutella xylostella (Lepidoptera: Plutellidae). J. Econ. Entomol. 2008, 101:1888-1896.