Effects of [3H]-BIDN, a novel bicyclic dinitrile radioligand for GABA-gated chloride channels of insects and vertebrates

British Journal of Pharmacology

Volumn 121, Issue 7, 1997, Pages 1496-1505

  Rauh, James J ^a   Banner, Eric ^a   Schnee, Michael E ^a   Cordova, Daniel ^a   Holyoke, Caleb W ^a   Howard, Michael H ^a   Bai, Donglin ^c   Buckingham, Steven D ^c   Hutton, Michael L ^c   Hamon, Alain ^c   Roush, Richard T ^b   Sattelle, David B ^c  

^a DUPONT COMPANY   (United States)

^b Department of Obstetrics Gynecology   (United States)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

3H BIDN; Convulsants; Dieldrin; Ionotropic GABA receptors; Rdl gene

Indexed keywords

1 (4 ETHYNYLPHENYL) 4 N PROPYL 2,6,7 TRIOXABICYCLO[2,2,2]OCTANE; 1 PHENYL 4 TERT BUTYL 2,6,7 TRIOXABICYCLO[2,2,2]OCTANE; 3,3 BIS(TRIFLUOROMETHYL)BICYCLO[2.2.1]HEPTANE 2,2 DICARBONITRILE; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID B RECEPTOR; 4 AMINOBUTYRIC ACID RECEPTOR; 4 TERT BUTYL 2,6,7 TRIOXA 1 PHOSPHABICYCLO[2,2,2]OCTANE 1 THIONE; CHLORIDE CHANNEL; CHLORIDE ION; COMPLEMENTARY DNA; DIELDRIN; ENDOSULFAN; HEPTACHLOR; HEPTACHLOR EPOXIDE; INSECTICIDE; MESSENGER RNA; OXOENDRIN; PICROTOXIN; RADIOLIGAND; RECEPTOR SUBUNIT; TERT BUTYLBICYCLOPHOSPHOROTHIOATE; UNCLASSIFIED DRUG; 3,3 BIS(TRIFLUOROMETHYL)BICYCLO(2.2.1)HEPTANE 2,2 DICARBONITRILE; 3,3-BIS(TRIFLUOROMETHYL)BICYCLO(2.2.1)HEPTANE-2,2-DICARBONITRILE; BICYCLO COMPOUND; CONVULSANT AGENT; DIAGNOSTIC AGENT; NITRILE; TRITIUM;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING SITE; BRAIN MEMBRANE; COCKROACH; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISSOCIATION; DROSOPHILA MELANOGASTER; INSECT; MALE; MEMBRANE BINDING; MUSCLE; NERVE; NONHUMAN; OOCYTE; PRIORITY JOURNAL; VERTEBRATE; XENOPUS; ANIMAL; BINDING COMPETITION; DRUG EFFECT; FEMALE; METABOLISM; PERIPLANETA; RADIOASSAY; RAT; XENOPUS LAEVIS;

ANIMALS; BICYCLO COMPOUNDS; BINDING, COMPETITIVE; CHLORIDE CHANNELS; CONVULSANTS; DROSOPHILA MELANOGASTER; FEMALE; INSECTICIDES; MALE; NITRILES; PERIPLANETA; RADIOLIGAND ASSAY; RATS; RECEPTORS, GABA; TRITIUM; XENOPUS LAEVIS;

EID: 0030610083     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701215     Document Type: Article

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