Replacement of asparagine with arginine at the extracellular end of the second transmembrane (M2) region of insect GABA receptors increases sensitivity to penicillin G

Invertebrate Neuroscience

Volumn 6, Issue 2, 2006, Pages 75-79

  Hosie, Alastair M ^a   Buckingham, Steven D ^b   Hamon, Alain ^b,c   Sattelle, David B ^b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID RECEPTOR; ARGININE; ASPARAGINE; DIELDRIN; MEMBRANE PROTEIN; PENICILLIN G;

AMINO ACID SUBSTITUTION; ARTICLE; DROSOPHILA; DRUG ANTAGONISM; DRUG POTENCY; DRUG SENSITIVITY; INSECT; MEMBRANE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; XENOPUS;

ANIMALS; ARGININE; ASPARAGINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DROSOPHILA; GABA ANTAGONISTS; GABA MODULATORS; INHIBITORY CONCENTRATION 50; INSECT PROTEINS; INSECTS; MEMBRANE POTENTIALS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; MUTATION; OOCYTES; PATCH-CLAMP TECHNIQUES; PENICILLIN G; RECEPTORS, GABA; XENOPUS;

EID: 33745011341     PISSN: 13542516     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10158-006-0020-4     Document Type: Article

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