Drug-resistant Drosophila indicate glutamate-gated chloride channels are targets for the antiparasitics nodulisporic acid and ivermectin

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 25, 2000, Pages 13949-13954

  Kane, Nanci S ^b   Hirschberg, Birgit ^b   Qian, Su ^b   Hunt, David ^b   Thomas, Brande ^b   Brochu, Richard ^b   Ludmerer, Steven W ^b   Zheng, Yingcong ^b   Smith, McHardy ^b   Arena, Joseph P ^b   Cohen, Charles J ^b   Schmatz, Dennis ^b   Warmke, Jeffrey ^b   Cully, Doris F ^b  

^a MERCK RESEARCH LABORATORIES   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTIPARASITIC AGENT; CHLORIDE CHANNEL; GLUTAMIC ACID; IVERMECTIN; NODULISPORIC ACID; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CHANNEL GATING; CROSS RESISTANCE; DROSOPHILA MELANOGASTER; GENE SEQUENCE; LOCOMOTION; MUTATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

ANIMALS; ANTIPARASITIC AGENTS; BASE SEQUENCE; CHLORIDE CHANNELS; CHROMOSOME MAPPING; DNA PRIMERS; DROSOPHILA MELANOGASTER; DRUG RESISTANCE; GLUTAMATES; IN SITU HYBRIDIZATION; INDOLES; IVERMECTIN; MOLECULAR SEQUENCE DATA; PHENOTYPE; XENOPUS LAEVIS;

ANIMALIA; DROSOPHILA MELANOGASTER; MELANOGASTER;

EID: 12944315071     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.240464697     Document Type: Article

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