A photoreactive probe that differentiates the binding sites of noncompetitive GABA receptor antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 6, 2011, Pages 1598-1600

  Shimotahira, Hiroshi ^a   Fusazaki, Sayaka ^a   Ikeda, Izumi ^a   Ozoe, Yoshihisa ^a  

^a SHIMANE UNIVERSITY   (Japan)

Author keywords

Fipronil; GABA; Noncompetitive antagonist; Photoreactive probe; Picrotoxinin

Indexed keywords

2 NITRO 4 [3 (TRIFLUOROMETHYL) 3H DIAZIRIN 3 YL]PHENYL 4 (4 METHOXYCARBONYL 1 BUTYNYL)BENZOATE; 4 AMINOBUTYRIC ACID RECEPTOR; 4 AMINOBUTYRIC ACID RECEPTOR BLOCKING AGENT; 4' ETHYNYL 4 N PROPYL BICYCLOORTHOBENZOATE; FIPRONIL; ION TRANSPORT AFFECTING AGENT; PICROTOXININ; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BRAIN MEMBRANE; CONTROLLED STUDY; CROSS LINKING; DRUG BINDING SITE; LIGAND BINDING; NONHUMAN; PEPTIDE MAPPING; PHOTOAFFINITY LABELING; PHOTOREACTIVITY; PROTEIN ANALYSIS; RAT; SYNTHESIS;

BINDING SITES; GABA ANTAGONISTS; MOLECULAR PROBES; PHOTOCHEMISTRY;

EID: 79952362702     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.01.118     Document Type: Article

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