GABA binding to an insect GABA receptor: A Molecular Dynamics and Mutagenesis Study

Biophysical Journal

Volumn 103, Issue 10, 2012, Pages 2071-2081

  Ashby, Jamie A ^a   McGonigle, Ian V ^a   Price, Kerry L ^a   Cohen, Netta ^b   Comitani, Federico ^b   Dougherty, Dennis A ^c   Molteni, Carla ^b   Lummis, Sarah C R ^a  

^a Department of Biochemistry ^*  (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c California Institute of Technology   (United States)

Author keywords

acetylcholine binding protein; AChBP; GABA; gamma aminobutyric acid; MD; molecular dynamics; nACh; nicotinic acetylcholine; RDL; resistant to dieldrin; RMSD; RMSF; root mean square displacement; root mean square fluctuation

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID RECEPTOR; LIGAND;

ANIMAL; ARTICLE; BINDING SITE; CHANNEL GATING; CHEMISTRY; GENETICS; INSECT; METABOLISM; MOLECULAR DYNAMICS; MUTAGENESIS; PROTEIN MULTIMERIZATION; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; STRUCTURAL HOMOLOGY; XENOPUS LAEVIS;

ANIMALS; BINDING SITES; GAMMA-AMINOBUTYRIC ACID; INSECTS; ION CHANNEL GATING; LIGANDS; MOLECULAR DYNAMICS SIMULATION; MUTAGENESIS; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, GABA; STRUCTURAL HOMOLOGY, PROTEIN; XENOPUS LAEVIS;

HEXAPODA;

EID: 84869393257     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1016/j.bpj.2012.10.016     Document Type: Article

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