Menthol shares general anesthetic activity and sites of action on the GABAA receptor with the intravenous agent, propofol

European Journal of Pharmacology

Volumn 590, Issue 1-3, 2008, Pages 120-126

  Watt, Erin E ^a   Betts, Brooke A ^a   Kotey, Francesca O ^a   Humbert, Danielle J ^a   Griffith, Theanne N ^a   Kelly, Elizabeth W ^a   Veneskey, Kelley C ^a   Gill, Nikhila ^a   Rowan, Kathleen C ^a   Jenkins, Andrew ^b   Hall, Adam C ^a  

^a SMITH COLLEGE   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Anesthesia; GABAA receptor; Menthol; Modulator; Oocyte; Propofol

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA1; 4 AMINOBUTYRIC ACID A RECEPTOR BETA2; 4 AMINOBUTYRIC ACID A RECEPTOR GAMMA2S; BARBITURIC ACID DERIVATIVE; BENZODIAZEPINE DERIVATIVE; CYCLOHEXANOL; ETOMIDATE; FLUMAZENIL; FLUNITRAZEPAM; ISOMENTHOL; ISOPULEGOL; MENTHOL; METHIONINE; PROPOFOL; RECEPTOR SUBTYPE; RECOMBINANT RECEPTOR; SEDATIVE AGENT; STEROID; TERPENOID DERIVATIVE; TERPINEOL; TRYPTOPHAN; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ARTICLE; CONCENTRATION RESPONSE; DRUG POTENCY; GENERAL ANESTHESIA; NONHUMAN; OOCYTE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; RIGHTING REFLEX; STRUCTURE ACTIVITY RELATION; TADPOLE; XENOPUS LAEVIS;

ANESTHETICS, GENERAL; ANESTHETICS, INTRAVENOUS; ANIMALS; CYCLOHEXANOLS; FLUMAZENIL; FLUNITRAZEPAM; MENTHOL; PENTOBARBITAL; PREGNANOLONE; PROPOFOL; RECEPTORS, GABA-A; XENOPUS;

EID: 48049115741     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2008.06.003     Document Type: Article

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