Nodulisporic acid opens insect glutamate-gated chloride channels: Identification of a new high affinity modulator

Biochemistry

Volumn 39, Issue 18, 2000, Pages 5543-5554

  Smith, McHardy M ^a   Warren, Vivien A ^a   Thomas, Brande S ^a   Brochu, Richard M ^a   Ertel, Eric A ^a,b   Rohrer, Susan ^a   Schaeffer, James ^a   Schmatz, Dennis ^a   Petuch, Brian R ^a   Tang, Yui Sing ^a   Meinke, Peter T ^a   Kaczorowski, Gregory J ^a   Cohen, Charles J ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE; CHLORIDE CHANNEL; IVERMECTIN; LACTONE; NODULISPORAMIDE; NODULISPORIC ACID; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CAENORHABDITIS; DROSOPHILA; GRASSHOPPER; LIGAND BINDING; NEMATODE; PRIORITY JOURNAL;

AMIDES; ANIMALS; BINDING SITES; BINDING, COMPETITIVE; CAENORHABDITIS ELEGANS; CELL MEMBRANE; CHLORIDE CHANNELS; DROSOPHILA MELANOGASTER; ELECTROPHYSIOLOGY; GRASSHOPPERS; INDOLES; INSECTICIDES; ION CHANNEL GATING; IVERMECTIN; KINETICS; MOLECULAR STRUCTURE; MOTOR NEURONS; PROTEIN BINDING;

CAENORHABDITIS; CAENORHABDITIS ELEGANS; DROSOPHILA MELANOGASTER; INSECTA; MELANOGASTER;

EID: 0034625116     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi992943i     Document Type: Article

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