The antiparasitic isoxazoline A1443 is a potent blocker of insect ligand-gated chloride channels

Biochemical and Biophysical Research Communications

Volumn 391, Issue 1, 2010, Pages 744-749

  Ozoe, Yoshihisa ^a   Asahi, Miho ^b   Ozoe, Fumiyo ^a   Nakahira, Kunimitsu ^b   Mita, Takeshi ^b  

^a SHIMANE UNIVERSITY   (Japan)

^b NISSAN CHEMICAL INDUSTRIES LTD   (Japan)

Author keywords

GABA; Glutamate; Ligand gated ion channel; Parasiticide; Receptor

Indexed keywords

4 AMINOBUTYRIC ACID; A 1443; ANTIPARASITIC AGENT; CHLORIDE CHANNEL; COMPLEMENTARY DNA; FIPRONIL; GLUTAMIC ACID; ISOXAZOLINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BRAIN MEMBRANE; CHLORIDE CURRENT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG POTENCY; DRUG SYNTHESIS; ELECTRODE; ELECTROPHYSIOLOGY; FEMALE; HOUSE FLY; IC 50; NONHUMAN; OOCYTE; PRIORITY JOURNAL; RAT; VOLTAGE CLAMP; WILD TYPE; XENOPUS;

ANIMALS; ANTIPARASITIC AGENTS; BICYCLO COMPOUNDS, HETEROCYCLIC; BRAIN; CATS; CHLORIDE CHANNELS; DOGS; FLEAS; GABA AGONISTS; GABA ANTAGONISTS; HOUSEFLIES; ION CHANNEL GATING; LIGANDS; MUTATION; RATS; RECEPTORS, GABA; RECEPTORS, GLUTAMATE; TICKS; XANTHINES; XENOPUS;

CANIS FAMILIARIS; CTENOCEPHALIDES FELIS; HEXAPODA; IXODIDA; RATTUS;

EID: 72949115496     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.11.131     Document Type: Article

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