Songorine, a diterpenoid alkaloid of the genus Aconitum, is a novel GABAA receptor antagonist in rat brain

Neuroscience Letters

Volumn 337, Issue 1, 2003, Pages 33-36

  Zhao, Xiao Yan ^a   Wang, Yuan ^a   Li, Yang ^a   Chen, Xue Qin ^a   Yang, Hui Hua ^a   Yue, Jian Min ^a   Hu, Guo Yuan ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Aconitum; Diterpenoid alkaloid; Hippocampus; Songorine; 3H Muscimol; aminobutyric acid; aminobutyric acidA receptor

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR BLOCKING AGENT; ACONITUM EXTRACT; ALKALOID; DITERPENOID; MUSCIMOL; SONGORINE; TYLOXAPOL; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRAIN; CHEMICAL BINDING; CONCENTRATION RESPONSE; CONTROLLED STUDY; HIPPOCAMPUS; MATHEMATICAL ANALYSIS; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; RAT; SCATCHARD PLOT; SYNAPTIC MEMBRANE;

ACONITUM; ALKALOIDS; ANIMALS; BINDING, COMPETITIVE; DRUGS, CHINESE HERBAL; GABA ANTAGONISTS; HIPPOCAMPUS; MALE; PATCH-CLAMP TECHNIQUES; PYRAMIDAL CELLS; RADIOLIGAND ASSAY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; SYNAPTIC MEMBRANES;

EID: 0037472353     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(02)01299-5     Document Type: Article

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