-
2
-
-
80054776671
-
Endoplasmic-reticulum calcium depletion and disease
-
Mekahli D., Bultynck G., Parys J.B., De Smedt H., Missiaen L. Endoplasmic-reticulum calcium depletion and disease. Cold Spring Harb. Perspect. Biol. 2011, 3.
-
(2011)
Cold Spring Harb. Perspect. Biol.
, vol.3
-
-
Mekahli, D.1
Bultynck, G.2
Parys, J.B.3
De Smedt, H.4
Missiaen, L.5
-
4
-
-
84863218983
-
2+ and apoptosis
-
2+ and apoptosis. Cell Calcium 2012, 52:36-43.
-
(2012)
Cell Calcium
, vol.52
, pp. 36-43
-
-
Giorgi, C.1
Baldassari, F.2
Bononi, A.3
Bonora, M.4
De Marchi, E.5
Marchi, S.6
Missiroli, S.7
Patergnani, S.8
Rimessi, A.9
Suski, J.M.10
Wieckowski, M.R.11
Pinton, P.12
-
5
-
-
84872591461
-
ER stress and UPR through dysregulated ER Ca2+ homeostasis and signaling
-
Springer, Netherlands, P. Agostinis, A. Samali (Eds.)
-
Vervliet T., Kiviluoto S., Bultynck G. ER stress and UPR through dysregulated ER Ca2+ homeostasis and signaling. Endoplasmic Reticulum Stress in Health and Disease 2012, 107-142. Springer, Netherlands. P. Agostinis, A. Samali (Eds.).
-
(2012)
Endoplasmic Reticulum Stress in Health and Disease
, pp. 107-142
-
-
Vervliet, T.1
Kiviluoto, S.2
Bultynck, G.3
-
6
-
-
80052621140
-
Calcium and cell death mechanisms: a perspective from the cell death community
-
Zhivotovsky B., Orrenius S. Calcium and cell death mechanisms: a perspective from the cell death community. Cell Calcium 2011, 50:211-221.
-
(2011)
Cell Calcium
, vol.50
, pp. 211-221
-
-
Zhivotovsky, B.1
Orrenius, S.2
-
7
-
-
84856111924
-
The unfolded protein response: controlling cell fate decisions under ER stress and beyond
-
Hetz C. The unfolded protein response: controlling cell fate decisions under ER stress and beyond. Nat. Rev. Mol. Cell Biol. 2012, 13:89-102.
-
(2012)
Nat. Rev. Mol. Cell Biol.
, vol.13
, pp. 89-102
-
-
Hetz, C.1
-
8
-
-
84872507615
-
Mitochondria associated membranes (MAMs) as critical hubs for apoptosis
-
Giorgi C., Wieckowski M.R., Pandolfi P.P., Pinton P. Mitochondria associated membranes (MAMs) as critical hubs for apoptosis. Commun. Integr. Biol. 2011, 4:334-335.
-
(2011)
Commun. Integr. Biol.
, vol.4
, pp. 334-335
-
-
Giorgi, C.1
Wieckowski, M.R.2
Pandolfi, P.P.3
Pinton, P.4
-
9
-
-
80053175932
-
Calcium signaling around mitochondria associated membranes (MAMs)
-
Patergnani S., Suski J.M., Agnoletto C., Bononi A., Bonora M., De Marchi E., Giorgi C., Marchi S., Missiroli S., Poletti F., Rimessi A., Duszynski J., Wieckowski M.R., Pinton P. Calcium signaling around mitochondria associated membranes (MAMs). Cell Commun. Signal. 2011, 9:19.
-
(2011)
Cell Commun. Signal.
, vol.9
, pp. 19
-
-
Patergnani, S.1
Suski, J.M.2
Agnoletto, C.3
Bononi, A.4
Bonora, M.5
De Marchi, E.6
Giorgi, C.7
Marchi, S.8
Missiroli, S.9
Poletti, F.10
Rimessi, A.11
Duszynski, J.12
Wieckowski, M.R.13
Pinton, P.14
-
10
-
-
3242728582
-
Subcellular localization of VDAC in mitochondria and ER in the cerebellum
-
Shoshan-Barmatz V., Zalk R., Gincel D., Vardi N. Subcellular localization of VDAC in mitochondria and ER in the cerebellum. Biochim. Biophys. Acta 2004, 1657:105-114.
-
(2004)
Biochim. Biophys. Acta
, vol.1657
, pp. 105-114
-
-
Shoshan-Barmatz, V.1
Zalk, R.2
Gincel, D.3
Vardi, N.4
-
11
-
-
24644455957
-
The voltage-dependent anion channel in endoplasmic/sarcoplasmic reticulum: characterization, modulation and possible function
-
Shoshan-Barmatz V., Israelson A. The voltage-dependent anion channel in endoplasmic/sarcoplasmic reticulum: characterization, modulation and possible function. J. Membr. Biol. 2005, 204:57-66.
-
(2005)
J. Membr. Biol.
, vol.204
, pp. 57-66
-
-
Shoshan-Barmatz, V.1
Israelson, A.2
-
12
-
-
84867271703
-
Coupling of ryanodine receptor 2 and voltage-dependent anion channel 2 is essential for Ca2+ transfer from the sarcoplasmic reticulum to the mitochondria in the heart
-
Min C.K., Yeom D.R., Lee K.E., Kwon H.K., Kang M., Kim Y.S., Park Z.Y., Jeon H., Kim do H. Coupling of ryanodine receptor 2 and voltage-dependent anion channel 2 is essential for Ca2+ transfer from the sarcoplasmic reticulum to the mitochondria in the heart. Biochem. J. 2012, 447:371-379.
-
(2012)
Biochem. J.
, vol.447
, pp. 371-379
-
-
Min, C.K.1
Yeom, D.R.2
Lee, K.E.3
Kwon, H.K.4
Kang, M.5
Kim, Y.S.6
Park, Z.Y.7
Jeon, H.8
Kim do, H.9
-
13
-
-
68649115556
-
2+ transfer from the ER to mitochondria: when, how and why
-
2+ transfer from the ER to mitochondria: when, how and why. Biochim. Biophys. Acta 2009, 1787:1342-1351.
-
(2009)
Biochim. Biophys. Acta
, vol.1787
, pp. 1342-1351
-
-
Rizzuto, R.1
Marchi, S.2
Bonora, M.3
Aguiari, P.4
Bononi, A.5
De Stefani, D.6
Giorgi, C.7
Leo, S.8
Rimessi, A.9
Siviero, R.10
Zecchini, E.11
Pinton, P.12
-
14
-
-
80051936634
-
A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter
-
De Stefani D., Raffaello A., Teardo E., Szabo I., Rizzuto R. A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter. Nature 2011, 476:336-340.
-
(2011)
Nature
, vol.476
, pp. 336-340
-
-
De Stefani, D.1
Raffaello, A.2
Teardo, E.3
Szabo, I.4
Rizzuto, R.5
-
15
-
-
80051946060
-
Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter
-
Baughman J.M., Perocchi F., Girgis H.S., Plovanich M., Belcher-Timme C.A., Sancak Y., Bao X.R., Strittmatter L., Goldberger O., Bogorad R.L., Koteliansky V., Mootha V.K. Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter. Nature 2011, 476:341-345.
-
(2011)
Nature
, vol.476
, pp. 341-345
-
-
Baughman, J.M.1
Perocchi, F.2
Girgis, H.S.3
Plovanich, M.4
Belcher-Timme, C.A.5
Sancak, Y.6
Bao, X.R.7
Strittmatter, L.8
Goldberger, O.9
Bogorad, R.L.10
Koteliansky, V.11
Mootha, V.K.12
-
16
-
-
84868027665
-
2+ uptake that regulates cell survival
-
2+ uptake that regulates cell survival. Cell 2012, 151:630-644.
-
(2012)
Cell
, vol.151
, pp. 630-644
-
-
Mallilankaraman, K.1
Doonan, P.2
Cardenas, C.3
Chandramoorthy, H.C.4
Muller, M.5
Miller, R.6
Hoffman, N.E.7
Gandhirajan, R.K.8
Molgo, J.9
Birnbaum, M.J.10
Rothberg, B.S.11
Mak, D.O.12
Foskett, J.K.13
Madesh, M.14
-
17
-
-
77950860036
-
Intracellular Ca2+ storage in health and disease: a dynamic equilibrium
-
Sammels E., Parys J.B., Missiaen L., De Smedt H., Bultynck G. Intracellular Ca2+ storage in health and disease: a dynamic equilibrium. Cell Calcium 2010, 47:297-314.
-
(2010)
Cell Calcium
, vol.47
, pp. 297-314
-
-
Sammels, E.1
Parys, J.B.2
Missiaen, L.3
De Smedt, H.4
Bultynck, G.5
-
18
-
-
77955041880
-
2+ transfer to mitochondria
-
2+ transfer to mitochondria. Cell 2010, 142:270-283.
-
(2010)
Cell
, vol.142
, pp. 270-283
-
-
Cardenas, C.1
Miller, R.A.2
Smith, I.3
Bui, T.4
Molgo, J.5
Muller, M.6
Vais, H.7
Cheung, K.H.8
Yang, J.9
Parker, I.10
Thompson, C.B.11
Birnbaum, M.J.12
Hallows, K.R.13
Foskett, J.K.14
-
19
-
-
78649954745
-
3 receptor
-
3 receptor. Neuron 2010, 68:865-878.
-
(2010)
Neuron
, vol.68
, pp. 865-878
-
-
Higo, T.1
Hamada, K.2
Hisatsune, C.3
Nukina, N.4
Hashikawa, T.5
Hattori, M.6
Nakamura, T.7
Mikoshiba, K.8
-
20
-
-
84861530662
-
ATP synthesis and storage
-
Bonora M., Patergnani S., Rimessi A., De Marchi E., Suski J.M., Bononi A., Giorgi C., Marchi S., Missiroli S., Poletti F., Wieckowski M.R., Pinton P. ATP synthesis and storage. Purinergic Signal 2012, 8:343-357.
-
(2012)
Purinergic Signal
, vol.8
, pp. 343-357
-
-
Bonora, M.1
Patergnani, S.2
Rimessi, A.3
De Marchi, E.4
Suski, J.M.5
Bononi, A.6
Giorgi, C.7
Marchi, S.8
Missiroli, S.9
Poletti, F.10
Wieckowski, M.R.11
Pinton, P.12
-
21
-
-
27144487808
-
3R
-
3R. Nat. Cell Biol. 2005, 7:1021-1028.
-
(2005)
Nat. Cell Biol.
, vol.7
, pp. 1021-1028
-
-
White, C.1
Li, C.2
Yang, J.3
Petrenko, N.B.4
Madesh, M.5
Thompson, C.B.6
Foskett, J.K.7
-
22
-
-
0027424601
-
Protein translocation into proteoliposomes reconstituted from purified components of the endoplasmic reticulum membrane
-
Gorlich D., Rapoport T.A. Protein translocation into proteoliposomes reconstituted from purified components of the endoplasmic reticulum membrane. Cell 1993, 75:615-630.
-
(1993)
Cell
, vol.75
, pp. 615-630
-
-
Gorlich, D.1
Rapoport, T.A.2
-
23
-
-
0029073398
-
Stage- and ribosome-specific alterations in nascent chain-Sec61p interactions accompany translocation across the ER membrane
-
Nicchitta C.V., Murphy E.C., Haynes R., Shelness G.S. Stage- and ribosome-specific alterations in nascent chain-Sec61p interactions accompany translocation across the ER membrane. J. Cell Biol. 1995, 129:957-970.
-
(1995)
J. Cell Biol.
, vol.129
, pp. 957-970
-
-
Nicchitta, C.V.1
Murphy, E.C.2
Haynes, R.3
Shelness, G.S.4
-
24
-
-
84864877220
-
2+ leakage from the ER
-
2+ leakage from the ER. EMBO J. 2012, 31:3282-3296.
-
(2012)
EMBO J.
, vol.31
, pp. 3282-3296
-
-
Schauble, N.1
Lang, S.2
Jung, M.3
Cappel, S.4
Schorr, S.5
Ulucan, O.6
Linxweiler, J.7
Dudek, J.8
Blum, R.9
Helms, V.10
Paton, A.W.11
Paton, J.C.12
Cavalie, A.13
Zimmermann, R.14
-
27
-
-
33745186921
-
2+-dependent control of the permeability properties of the mitochondrial outer membrane and voltage-dependent anion-selective channel (VDAC)
-
2+-dependent control of the permeability properties of the mitochondrial outer membrane and voltage-dependent anion-selective channel (VDAC). J. Biol. Chem. 2006, 281:17347-17358.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 17347-17358
-
-
Bathori, G.1
Csordas, G.2
Garcia-Perez, C.3
Davies, E.4
Hajnoczky, G.5
-
28
-
-
33845977959
-
Mitochondrial membrane permeabilization in cell death
-
Kroemer G., Galluzzi L., Brenner C. Mitochondrial membrane permeabilization in cell death. Physiol. Rev. 2007, 87:99-163.
-
(2007)
Physiol. Rev.
, vol.87
, pp. 99-163
-
-
Kroemer, G.1
Galluzzi, L.2
Brenner, C.3
-
29
-
-
68949137001
-
2+ requirement for mitochondrial permeability transition pore (mPTP) opening
-
2+ requirement for mitochondrial permeability transition pore (mPTP) opening. J. Biol. Chem. 2009, 284:20796-20803.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 20796-20803
-
-
Baumgartner, H.K.1
Gerasimenko, J.V.2
Thorne, C.3
Ferdek, P.4
Pozzan, T.5
Tepikin, A.V.6
Petersen, O.H.7
Sutton, R.8
Watson, A.J.9
Gerasimenko, O.V.10
-
30
-
-
0030973158
-
T cells deficient in inositol 1,4,5-trisphosphate receptor are resistant to apoptosis
-
Jayaraman T., Marks A.R. T cells deficient in inositol 1,4,5-trisphosphate receptor are resistant to apoptosis. Mol. Cell. Biol. 1997, 17:3005-3012.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 3005-3012
-
-
Jayaraman, T.1
Marks, A.R.2
-
31
-
-
5644261222
-
Caspase-3-induced truncation of type 1 inositol trisphosphate receptor accelerates apoptotic cell death and induces inositol trisphosphate-independent calcium release during apoptosis
-
Assefa Z., Bultynck G., Szlufcik K., Nadif Kasri N., Vermassen E., Goris J., Missiaen L., Callewaert G., Parys J.B., De Smedt H. Caspase-3-induced truncation of type 1 inositol trisphosphate receptor accelerates apoptotic cell death and induces inositol trisphosphate-independent calcium release during apoptosis. J. Biol. Chem. 2004, 279:43227-43236.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 43227-43236
-
-
Assefa, Z.1
Bultynck, G.2
Szlufcik, K.3
Nadif Kasri, N.4
Vermassen, E.5
Goris, J.6
Missiaen, L.7
Callewaert, G.8
Parys, J.B.9
De Smedt, H.10
-
32
-
-
36348987603
-
Role of inositol 1,4,5-trisphosphate receptors in apoptosis in DT40 lymphocytes
-
Khan M.T., Bhanumathy C.D., Schug Z.T., Joseph S.K. Role of inositol 1,4,5-trisphosphate receptors in apoptosis in DT40 lymphocytes. J. Biol. Chem. 2007, 282:32983-32990.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 32983-32990
-
-
Khan, M.T.1
Bhanumathy, C.D.2
Schug, Z.T.3
Joseph, S.K.4
-
33
-
-
46649097078
-
Requirement of inositol 1,4,5-trisphosphate receptors for tumor-mediated lymphocyte apoptosis
-
Steinmann C., Landsverk M.L., Barral J.M., Boehning D. Requirement of inositol 1,4,5-trisphosphate receptors for tumor-mediated lymphocyte apoptosis. J. Biol. Chem. 2008, 283:13506-13509.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 13506-13509
-
-
Steinmann, C.1
Landsverk, M.L.2
Barral, J.M.3
Boehning, D.4
-
34
-
-
38849174384
-
2+ signalling
-
2+ signalling. Biol. Cell 2008, 100:39-49.
-
(2008)
Biol. Cell
, vol.100
, pp. 39-49
-
-
Verbert, L.1
Lee, B.2
Kocks, S.L.3
Assefa, Z.4
Parys, J.B.5
Missiaen, L.6
Callewaert, G.7
Fissore, R.A.8
De Smedt, H.9
Bultynck, G.10
-
36
-
-
84872570280
-
IP3 receptor-binding partners in cell-death mechanisms
-
Kiviluoto S., Akl H., Vervliet T., Bultynck G., Parys J.B., Missiaen L., De Smedt H. IP3 receptor-binding partners in cell-death mechanisms. Wiley Interdisciplinary Reviews: Membrane Transport and Signaling 2012.
-
(2012)
Wiley Interdisciplinary Reviews: Membrane Transport and Signaling
-
-
Kiviluoto, S.1
Akl, H.2
Vervliet, T.3
Bultynck, G.4
Parys, J.B.5
Missiaen, L.6
De Smedt, H.7
-
37
-
-
42549164808
-
2+ for cancer cell proliferation and survival
-
2+ for cancer cell proliferation and survival. Nat. Rev. Cancer 2008, 8:361-375.
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 361-375
-
-
Roderick, H.L.1
Cook, S.J.2
-
38
-
-
70449088871
-
2+-dependent mitochondrial apoptosis
-
2+-dependent mitochondrial apoptosis. Mol. Cell 2009, 36:500-511.
-
(2009)
Mol. Cell
, vol.36
, pp. 500-511
-
-
Sano, R.1
Annunziata, I.2
Patterson, A.3
Moshiach, S.4
Gomero, E.5
Opferman, J.6
Forte, M.7
d'Azzo, A.8
-
39
-
-
84857873334
-
Sphingolipid metabolism cooperates with BAK and BAX to promote the mitochondrial pathway of apoptosis
-
Chipuk J.E., McStay G.P., Bharti A., Kuwana T., Clarke C.J., Siskind L.J., Obeid L.M., Green D.R. Sphingolipid metabolism cooperates with BAK and BAX to promote the mitochondrial pathway of apoptosis. Cell 2012, 148:988-1000.
-
(2012)
Cell
, vol.148
, pp. 988-1000
-
-
Chipuk, J.E.1
McStay, G.P.2
Bharti, A.3
Kuwana, T.4
Clarke, C.J.5
Siskind, L.J.6
Obeid, L.M.7
Green, D.R.8
-
40
-
-
33746291023
-
Increased lipogenesis in cancer cells: new players, novel targets
-
Swinnen J.V., Brusselmans K., Verhoeven G. Increased lipogenesis in cancer cells: new players, novel targets. Curr. Opin. Clin. Nutr. Metab. Care 2006, 9:358-365.
-
(2006)
Curr. Opin. Clin. Nutr. Metab. Care
, vol.9
, pp. 358-365
-
-
Swinnen, J.V.1
Brusselmans, K.2
Verhoeven, G.3
-
41
-
-
0033607673
-
Inositol 1,4,5-trisphosphate receptor type 1 is a substrate for caspase-3 and is cleaved during apoptosis in a caspase-3-dependent manner
-
Hirota J., Furuichi T., Mikoshiba K. Inositol 1,4,5-trisphosphate receptor type 1 is a substrate for caspase-3 and is cleaved during apoptosis in a caspase-3-dependent manner. J. Biol. Chem. 1999, 274:34433-34437.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 34433-34437
-
-
Hirota, J.1
Furuichi, T.2
Mikoshiba, K.3
-
42
-
-
9144262298
-
The regulatory domain of the inositol 1,4,5-trisphosphate receptor is necessary to keep the channel domain closed: possible physiological significance of specific cleavage by caspase 3
-
Nakayama T., Hattori M., Uchida K., Nakamura T., Tateishi Y., Bannai H., Iwai M., Michikawa T., Inoue T., Mikoshiba K. The regulatory domain of the inositol 1,4,5-trisphosphate receptor is necessary to keep the channel domain closed: possible physiological significance of specific cleavage by caspase 3. Biochem. J. 2004, 377:299-307.
-
(2004)
Biochem. J.
, vol.377
, pp. 299-307
-
-
Nakayama, T.1
Hattori, M.2
Uchida, K.3
Nakamura, T.4
Tateishi, Y.5
Bannai, H.6
Iwai, M.7
Michikawa, T.8
Inoue, T.9
Mikoshiba, K.10
-
43
-
-
0344825875
-
Cytochrome c binds to inositol (1,4,5) trisphosphate receptors, amplifying calcium-dependent apoptosis
-
Boehning D., Patterson R.L., Sedaghat L., Glebova N.O., Kurosaki T., Snyder S.H. Cytochrome c binds to inositol (1,4,5) trisphosphate receptors, amplifying calcium-dependent apoptosis. Nat. Cell Biol. 2003, 5:1051-1061.
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 1051-1061
-
-
Boehning, D.1
Patterson, R.L.2
Sedaghat, L.3
Glebova, N.O.4
Kurosaki, T.5
Snyder, S.H.6
-
44
-
-
13444274308
-
A peptide inhibitor of cytochrome c/inositol 1,4,5-trisphosphate receptor binding blocks intrinsic and extrinsic cell death pathways
-
Boehning D., van Rossum D.B., Patterson R.L., Snyder S.H. A peptide inhibitor of cytochrome c/inositol 1,4,5-trisphosphate receptor binding blocks intrinsic and extrinsic cell death pathways. Proc. Natl. Acad. Sci. U. S. A. 2005, 102:1466-1471.
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 1466-1471
-
-
Boehning, D.1
van Rossum, D.B.2
Patterson, R.L.3
Snyder, S.H.4
-
45
-
-
84862577826
-
Type 1 inositol-1,4,5-trisphosphate receptor is a late substrate of caspases during apoptosis
-
Elkoreh G., Blais V., Beliveau E., Guillemette G., Denault J.B. Type 1 inositol-1,4,5-trisphosphate receptor is a late substrate of caspases during apoptosis. J. Cell. Biochem. 2012, 113:2775-2784.
-
(2012)
J. Cell. Biochem.
, vol.113
, pp. 2775-2784
-
-
Elkoreh, G.1
Blais, V.2
Beliveau, E.3
Guillemette, G.4
Denault, J.B.5
-
46
-
-
84873523771
-
Caspase 3 cleavage of the inositol 1,4,5-trisphosphate receptor does not contribute to apoptotic calcium release
-
Akimzhanov A.M., Barral J.M., Boehning D. Caspase 3 cleavage of the inositol 1,4,5-trisphosphate receptor does not contribute to apoptotic calcium release. Cell Calcium 2012, 10.1016/j.ceca.2012.10.002.
-
(2012)
Cell Calcium
-
-
Akimzhanov, A.M.1
Barral, J.M.2
Boehning, D.3
-
47
-
-
80053925001
-
2+ homeostasis
-
2+ homeostasis. J. Biol. Chem. 2011, 286:35998-36010.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 35998-36010
-
-
Kopil, C.M.1
Vais, H.2
Cheung, K.H.3
Siebert, A.P.4
Mak, D.O.5
Foskett, J.K.6
Neumar, R.W.7
-
48
-
-
84855679389
-
2+ signaling and apoptosis by the BH4 domain of Bcl-2 versus Bcl-Xl
-
2+ signaling and apoptosis by the BH4 domain of Bcl-2 versus Bcl-Xl. Cell Death Differ. 2012, 19:295-309.
-
(2012)
Cell Death Differ.
, vol.19
, pp. 295-309
-
-
Monaco, G.1
Decrock, E.2
Akl, H.3
Ponsaerts, R.4
Vervliet, T.5
Luyten, T.6
De Maeyer, M.7
Missiaen, L.8
Distelhorst, C.W.9
De Smedt, H.10
Parys, J.B.11
Leybaert, L.12
Bultynck, G.13
-
49
-
-
84860722401
-
3 through gap junctions is critical, but not sufficient, for the spread of apoptosis
-
3 through gap junctions is critical, but not sufficient, for the spread of apoptosis. Cell Death Differ. 2012, 19:947-957.
-
(2012)
Cell Death Differ.
, vol.19
, pp. 947-957
-
-
Decrock, E.1
Krysko, D.V.2
Vinken, M.3
Kaczmarek, A.4
Crispino, G.5
Bol, M.6
Wang, N.7
De Bock, M.8
De Vuyst, E.9
Naus, C.C.10
Rogiers, V.11
Vandenabeele, P.12
Erneux, C.13
Mammano, F.14
Bultynck, G.15
Leybaert, L.16
-
50
-
-
84859491380
-
2+-entry pathway
-
2+-entry pathway. J. Biol. Chem. 2012, 287:12250-12266.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 12250-12266
-
-
De Bock, M.1
Wang, N.2
Bol, M.3
Decrock, E.4
Ponsaerts, R.5
Bultynck, G.6
Dupont, G.7
Leybaert, L.8
-
51
-
-
70350366761
-
G-protein-coupled receptor kinase-interacting proteins inhibit apoptosis by inositol 1,4,5-triphosphate receptor-mediated Ca2+ signal regulation
-
Zhang S., Hisatsune C., Matsu-Ura T., Mikoshiba K. G-protein-coupled receptor kinase-interacting proteins inhibit apoptosis by inositol 1,4,5-triphosphate receptor-mediated Ca2+ signal regulation. J. Biol. Chem. 2009, 284:29158-29169.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 29158-29169
-
-
Zhang, S.1
Hisatsune, C.2
Matsu-Ura, T.3
Mikoshiba, K.4
-
52
-
-
47049128540
-
2+ channel activity in the endoplasmic reticulum
-
2+ channel activity in the endoplasmic reticulum. J. Biol. Chem. 2008, 283:15946-15955.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 15946-15955
-
-
Kim, H.R.1
Lee, G.H.2
Ha, K.C.3
Ahn, T.4
Moon, J.Y.5
Lee, B.J.6
Cho, S.G.7
Kim, S.8
Seo, Y.R.9
Shin, Y.J.10
Chae, S.W.11
Reed, J.C.12
Chae, H.J.13
-
53
-
-
84856070930
-
2+-permeable channel pore
-
2+-permeable channel pore. J. Biol. Chem. 2012, 287:2544-2557.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 2544-2557
-
-
Bultynck, G.1
Kiviluoto, S.2
Henke, N.3
Ivanova, H.4
Schneider, L.5
Rybalchenko, V.6
Luyten, T.7
Nuyts, K.8
De Borggraeve, W.9
Bezprozvanny, I.10
Parys, J.B.11
De Smedt, H.12
Missiaen, L.13
Methner, A.14
-
54
-
-
4143087106
-
BI-1 regulates an apoptosis pathway linked to endoplasmic reticulum stress
-
Chae H.J., Kim H.R., Xu C., Bailly-Maitre B., Krajewska M., Krajewski S., Banares S., Cui J., Digicaylioglu M., Ke N., Kitada S., Monosov E., Thomas M., Kress C.L., Babendure J.R., Tsien R.Y., Lipton S.A., Reed J.C. BI-1 regulates an apoptosis pathway linked to endoplasmic reticulum stress. Mol. Cell 2004, 15:355-366.
-
(2004)
Mol. Cell
, vol.15
, pp. 355-366
-
-
Chae, H.J.1
Kim, H.R.2
Xu, C.3
Bailly-Maitre, B.4
Krajewska, M.5
Krajewski, S.6
Banares, S.7
Cui, J.8
Digicaylioglu, M.9
Ke, N.10
Kitada, S.11
Monosov, E.12
Thomas, M.13
Kress, C.L.14
Babendure, J.R.15
Tsien, R.Y.16
Lipton, S.A.17
Reed, J.C.18
-
55
-
-
69149093396
-
Intramitochondrial calcium regulation by the FHIT gene product sensitizes to apoptosis
-
Rimessi A., Marchi S., Fotino C., Romagnoli A., Huebner K., Croce C.M., Pinton P., Rizzuto R. Intramitochondrial calcium regulation by the FHIT gene product sensitizes to apoptosis. Proc. Natl. Acad. Sci. U. S. A. 2009, 106:12753-12758.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 12753-12758
-
-
Rimessi, A.1
Marchi, S.2
Fotino, C.3
Romagnoli, A.4
Huebner, K.5
Croce, C.M.6
Pinton, P.7
Rizzuto, R.8
-
56
-
-
84866367672
-
Calcium channels and pumps in cancer: changes and consequences
-
Monteith G.R., Davis F.M., Roberts-Thomson S.J. Calcium channels and pumps in cancer: changes and consequences. J. Biol. Chem. 2012, 287:31666-31673.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 31666-31673
-
-
Monteith, G.R.1
Davis, F.M.2
Roberts-Thomson, S.J.3
-
57
-
-
79959527283
-
Endoplasmic reticulum calcium pumps and cancer
-
Arbabian A., Brouland J.P., Gelebart P., Kovacs T., Bobe R., Enouf J., Papp B. Endoplasmic reticulum calcium pumps and cancer. Biofactors 2011, 37:139-149.
-
(2011)
Biofactors
, vol.37
, pp. 139-149
-
-
Arbabian, A.1
Brouland, J.P.2
Gelebart, P.3
Kovacs, T.4
Bobe, R.5
Enouf, J.6
Papp, B.7
-
58
-
-
79960759956
-
Calcium in tumour metastasis: new roles for known actors
-
Prevarskaya N., Skryma R., Shuba Y. Calcium in tumour metastasis: new roles for known actors. Nat. Rev. Cancer 2011, 11:609-618.
-
(2011)
Nat. Rev. Cancer
, vol.11
, pp. 609-618
-
-
Prevarskaya, N.1
Skryma, R.2
Shuba, Y.3
-
59
-
-
79952284127
-
Hallmarks of cancer: the next generation
-
Hanahan D., Weinberg R.A. Hallmarks of cancer: the next generation. Cell 2011, 144:646-674.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
61
-
-
78649714362
-
The type III inositol 1,4,5-trisphosphate receptor is associated with aggressiveness of colorectal carcinoma
-
Shibao K., Fiedler M.J., Nagata J., Minagawa N., Hirata K., Nakayama Y., Iwakiri Y., Nathanson M.H., Yamaguchi K. The type III inositol 1,4,5-trisphosphate receptor is associated with aggressiveness of colorectal carcinoma. Cell Calcium 2010, 48:315-323.
-
(2010)
Cell Calcium
, vol.48
, pp. 315-323
-
-
Shibao, K.1
Fiedler, M.J.2
Nagata, J.3
Minagawa, N.4
Hirata, K.5
Nakayama, Y.6
Iwakiri, Y.7
Nathanson, M.H.8
Yamaguchi, K.9
-
62
-
-
76249129621
-
Caffeine-mediated inhibition of calcium release channel inositol 1,4,5-trisphosphate receptor subtype 3 blocks glioblastoma invasion and extends survival
-
Kang S.S., Han K.S., Ku B.M., Lee Y.K., Hong J., Shin H.Y., Almonte A.G., Woo D.H., Brat D.J., Hwang E.M., Yoo S.H., Chung C.K., Park S.H., Paek S.H., Roh E.J., Lee S.J., Park J.Y., Traynelis S.F., Lee C.J. Caffeine-mediated inhibition of calcium release channel inositol 1,4,5-trisphosphate receptor subtype 3 blocks glioblastoma invasion and extends survival. Cancer Res. 2010, 70:1173-1183.
-
(2010)
Cancer Res.
, vol.70
, pp. 1173-1183
-
-
Kang, S.S.1
Han, K.S.2
Ku, B.M.3
Lee, Y.K.4
Hong, J.5
Shin, H.Y.6
Almonte, A.G.7
Woo, D.H.8
Brat, D.J.9
Hwang, E.M.10
Yoo, S.H.11
Chung, C.K.12
Park, S.H.13
Paek, S.H.14
Roh, E.J.15
Lee, S.J.16
Park, J.Y.17
Traynelis, S.F.18
Lee, C.J.19
-
63
-
-
20044391606
-
3R1) modulates the acquisition of cisplatin resistance in bladder cancer cell lines
-
3R1) modulates the acquisition of cisplatin resistance in bladder cancer cell lines. Oncogene 2005, 24:1396-1402.
-
(2005)
Oncogene
, vol.24
, pp. 1396-1402
-
-
Tsunoda, T.1
Koga, H.2
Yokomizo, A.3
Tatsugami, K.4
Eto, M.5
Inokuchi, J.6
Hirata, A.7
Masuda, K.8
Okumura, K.9
Naito, S.10
-
64
-
-
33845339607
-
Paclitaxel induces calcium oscillations via an inositol 1,4,5-trisphosphate receptor and neuronal calcium sensor 1-dependent mechanism
-
Boehmerle W., Splittgerber U., Lazarus M.B., McKenzie K.M., Johnston D.G., Austin D.J., Ehrlich B.E. Paclitaxel induces calcium oscillations via an inositol 1,4,5-trisphosphate receptor and neuronal calcium sensor 1-dependent mechanism. Proc. Natl. Acad. Sci. U. S. A. 2006, 103:18356-18361.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 18356-18361
-
-
Boehmerle, W.1
Splittgerber, U.2
Lazarus, M.B.3
McKenzie, K.M.4
Johnston, D.G.5
Austin, D.J.6
Ehrlich, B.E.7
-
65
-
-
79953709767
-
KRAS-induced actin-interacting protein is required for the proper localization of inositol 1,4,5-trisphosphate receptor in the epithelial cells
-
Fujimoto T., Machida T., Tanaka Y., Tsunoda T., Doi K., Ota T., Okamura T., Kuroki M., Shirasawa S. KRAS-induced actin-interacting protein is required for the proper localization of inositol 1,4,5-trisphosphate receptor in the epithelial cells. Biochem. Biophys. Res. Commun. 2011, 407:438-443.
-
(2011)
Biochem. Biophys. Res. Commun.
, vol.407
, pp. 438-443
-
-
Fujimoto, T.1
Machida, T.2
Tanaka, Y.3
Tsunoda, T.4
Doi, K.5
Ota, T.6
Okamura, T.7
Kuroki, M.8
Shirasawa, S.9
-
66
-
-
0032578999
-
Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B
-
Stephens L., Anderson K., Stokoe D., Erdjument-Bromage H., Painter G.F., Holmes A.B., Gaffney P.R., Reese C.B., McCormick F., Tempst P., Coadwell J., Hawkins P.T. Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B. Science 1998, 279:710-714.
-
(1998)
Science
, vol.279
, pp. 710-714
-
-
Stephens, L.1
Anderson, K.2
Stokoe, D.3
Erdjument-Bromage, H.4
Painter, G.F.5
Holmes, A.B.6
Gaffney, P.R.7
Reese, C.B.8
McCormick, F.9
Tempst, P.10
Coadwell, J.11
Hawkins, P.T.12
-
67
-
-
1342321750
-
PI 3-kinase, Akt and cell survival
-
Downward J. PI 3-kinase, Akt and cell survival. Semin. Cell Dev. Biol. 2004, 15:177-182.
-
(2004)
Semin. Cell Dev. Biol.
, vol.15
, pp. 177-182
-
-
Downward, J.1
-
68
-
-
34547838420
-
PTEN, more than the AKT pathway
-
Blanco-Aparicio C., Renner O., Leal J.F., Carnero A. PTEN, more than the AKT pathway. Carcinogenesis 2007, 28:1379-1386.
-
(2007)
Carcinogenesis
, vol.28
, pp. 1379-1386
-
-
Blanco-Aparicio, C.1
Renner, O.2
Leal, J.F.3
Carnero, A.4
-
69
-
-
0035936653
-
PDK2: a complex tail in one Akt
-
Chan T.O., Tsichlis P.N. PDK2: a complex tail in one Akt. Sci. STKE 2001, 2001:e1.
-
(2001)
Sci. STKE
, vol.2001
-
-
Chan, T.O.1
Tsichlis, P.N.2
-
71
-
-
0033856110
-
PTEN, a unique tumor suppressor gene
-
Dahia P.L. PTEN, a unique tumor suppressor gene. Endocr. Relat. Cancer 2000, 7:115-129.
-
(2000)
Endocr. Relat. Cancer
, vol.7
, pp. 115-129
-
-
Dahia, P.L.1
-
73
-
-
23844445836
-
Colorectal cancer: mutations in a signalling pathway
-
Parsons D.W., Wang T.L., Samuels Y., Bardelli A., Cummins J.M., DeLong L., Silliman N., Ptak J., Szabo S., Willson J.K., Markowitz S., Kinzler K.W., Vogelstein B., Lengauer C., Velculescu V.E. Colorectal cancer: mutations in a signalling pathway. Nature 2005, 436:792.
-
(2005)
Nature
, vol.436
, pp. 792
-
-
Parsons, D.W.1
Wang, T.L.2
Samuels, Y.3
Bardelli, A.4
Cummins, J.M.5
DeLong, L.6
Silliman, N.7
Ptak, J.8
Szabo, S.9
Willson, J.K.10
Markowitz, S.11
Kinzler, K.W.12
Vogelstein, B.13
Lengauer, C.14
Velculescu, V.E.15
-
74
-
-
33646706052
-
Oncogenic PI3K and its role in cancer
-
Samuels Y., Ericson K. Oncogenic PI3K and its role in cancer. Curr. Opin. Oncol. 2006, 18:77-82.
-
(2006)
Curr. Opin. Oncol.
, vol.18
, pp. 77-82
-
-
Samuels, Y.1
Ericson, K.2
-
75
-
-
0036632368
-
The phosphatidylinositol 3-Kinase AKT pathway in human cancer
-
Vivanco I., Sawyers C.L. The phosphatidylinositol 3-Kinase AKT pathway in human cancer. Nat. Rev. Cancer 2002, 2:489-501.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 489-501
-
-
Vivanco, I.1
Sawyers, C.L.2
-
76
-
-
77949452524
-
The PKB/AKT pathway in cancer
-
Carnero A. The PKB/AKT pathway in cancer. Curr. Pharm. Des. 2010, 16:34-44.
-
(2010)
Curr. Pharm. Des.
, vol.16
, pp. 34-44
-
-
Carnero, A.1
-
77
-
-
80052962211
-
Akt, FoxO and regulation of apoptosis
-
Zhang X., Tang N., Hadden T.J., Rishi A.K. Akt, FoxO and regulation of apoptosis. Biochim. Biophys. Acta 2011, 1813:1978-1986.
-
(2011)
Biochim. Biophys. Acta
, vol.1813
, pp. 1978-1986
-
-
Zhang, X.1
Tang, N.2
Hadden, T.J.3
Rishi, A.K.4
-
78
-
-
49849093007
-
Unravelling the tumor-suppressive functions of FOXO proteins
-
Dansen T.B., Burgering B.M. Unravelling the tumor-suppressive functions of FOXO proteins. Trends Cell Biol. 2008, 18:421-429.
-
(2008)
Trends Cell Biol.
, vol.18
, pp. 421-429
-
-
Dansen, T.B.1
Burgering, B.M.2
-
79
-
-
0038075338
-
Decision making by p53: life, death and cancer
-
Oren M. Decision making by p53: life, death and cancer. Cell Death Differ. 2003, 10:431-442.
-
(2003)
Cell Death Differ.
, vol.10
, pp. 431-442
-
-
Oren, M.1
-
81
-
-
11144358645
-
High frequency of mutations of the PIK3CA gene in human cancers
-
Samuels Y., Wang Z., Bardelli A., Silliman N., Ptak J., Szabo S., Yan H., Gazdar A., Powell S.M., Riggins G.J., Willson J.K., Markowitz S., Kinzler K.W., Vogelstein B., Velculescu V.E. High frequency of mutations of the PIK3CA gene in human cancers. Science 2004, 304:554.
-
(2004)
Science
, vol.304
, pp. 554
-
-
Samuels, Y.1
Wang, Z.2
Bardelli, A.3
Silliman, N.4
Ptak, J.5
Szabo, S.6
Yan, H.7
Gazdar, A.8
Powell, S.M.9
Riggins, G.J.10
Willson, J.K.11
Markowitz, S.12
Kinzler, K.W.13
Vogelstein, B.14
Velculescu, V.E.15
-
82
-
-
84859778293
-
MTOR signaling in growth control and disease
-
Laplante M., Sabatini D.M. mTOR signaling in growth control and disease. Cell 2012, 149:274-293.
-
(2012)
Cell
, vol.149
, pp. 274-293
-
-
Laplante, M.1
Sabatini, D.M.2
-
83
-
-
84865589453
-
Hallmarks of cancer: of all cancer cells, all the time?
-
Floor S.L., Dumont J.E., Maenhaut C., Raspe E. Hallmarks of cancer: of all cancer cells, all the time?. Trends Mol. Med. 2012, 18:509-515.
-
(2012)
Trends Mol. Med.
, vol.18
, pp. 509-515
-
-
Floor, S.L.1
Dumont, J.E.2
Maenhaut, C.3
Raspe, E.4
-
84
-
-
32944457518
-
MTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt
-
O'Reilly K.E., Rojo F., She Q.B., Solit D., Mills G.B., Smith D., Lane H., Hofmann F., Hicklin D.J., Ludwig D.L., Baselga J., Rosen N. mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt. Cancer Res. 2006, 66:1500-1508.
-
(2006)
Cancer Res.
, vol.66
, pp. 1500-1508
-
-
O'Reilly, K.E.1
Rojo, F.2
She, Q.B.3
Solit, D.4
Mills, G.B.5
Smith, D.6
Lane, H.7
Hofmann, F.8
Hicklin, D.J.9
Ludwig, D.L.10
Baselga, J.11
Rosen, N.12
-
85
-
-
33645642577
-
Akt kinase phosphorylation of inositol 1,4,5-trisphosphate receptors
-
Khan M.T., Wagner L., Yule D.I., Bhanumathy C., Joseph S.K. Akt kinase phosphorylation of inositol 1,4,5-trisphosphate receptors. J. Biol. Chem. 2006, 281:3731-3737.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 3731-3737
-
-
Khan, M.T.1
Wagner, L.2
Yule, D.I.3
Bhanumathy, C.4
Joseph, S.K.5
-
86
-
-
40649096621
-
Phosphorylation of inositol 1,4,5-trisphosphate receptors by protein kinase B/Akt inhibits Ca2+ release and apoptosis
-
Szado T., Vanderheyden V., Parys J.B., De Smedt H., Rietdorf K., Kotelevets L., Chastre E., Khan F., Landegren U., Soderberg O., Bootman M.D., Roderick H.L. Phosphorylation of inositol 1,4,5-trisphosphate receptors by protein kinase B/Akt inhibits Ca2+ release and apoptosis. Proc. Natl. Acad. Sci. U.S.A. 2008, 105:2427-2432.
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 2427-2432
-
-
Szado, T.1
Vanderheyden, V.2
Parys, J.B.3
De Smedt, H.4
Rietdorf, K.5
Kotelevets, L.6
Chastre, E.7
Khan, F.8
Landegren, U.9
Soderberg, O.10
Bootman, M.D.11
Roderick, H.L.12
-
87
-
-
51649083933
-
2+-dependent apoptotic stimuli
-
2+-dependent apoptotic stimuli. Biochem. Biophys. Res. Commun. 2008, 375:501-505.
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.375
, pp. 501-505
-
-
Marchi, S.1
Rimessi, A.2
Giorgi, C.3
Baldini, C.4
Ferroni, L.5
Rizzuto, R.6
Pinton, P.7
-
88
-
-
0032558822
-
Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC
-
Haas-Kogan D., Shalev N., Wong M., Mills G., Yount G., Stokoe D. Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC. Curr. Biol. 1998, 8:1195-1198.
-
(1998)
Curr. Biol.
, vol.8
, pp. 1195-1198
-
-
Haas-Kogan, D.1
Shalev, N.2
Wong, M.3
Mills, G.4
Yount, G.5
Stokoe, D.6
-
89
-
-
0033945128
-
Type 3 inositol 1,4,5-trisphosphate receptor modulates cell death
-
Blackshaw S., Sawa A., Sharp A.H., Ross C.A., Snyder S.H., Khan A.A. Type 3 inositol 1,4,5-trisphosphate receptor modulates cell death. FASEB J. 2000, 14:1375-1379.
-
(2000)
FASEB J.
, vol.14
, pp. 1375-1379
-
-
Blackshaw, S.1
Sawa, A.2
Sharp, A.H.3
Ross, C.A.4
Snyder, S.H.5
Khan, A.A.6
-
90
-
-
28844453210
-
2+ signals into mitochondria
-
2+ signals into mitochondria. J. Biol. Chem. 2005, 280:40892-40900.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 40892-40900
-
-
Mendes, C.C.1
Gomes, D.A.2
Thompson, M.3
Souto, N.C.4
Goes, T.S.5
Goes, A.M.6
Rodrigues, M.A.7
Gomez, M.V.8
Nathanson, M.H.9
Leite, M.F.10
-
91
-
-
77955300013
-
Calcium-dependent conformational changes in inositol trisphosphate receptors
-
Anyatonwu G., Khan M.T., Schug Z.T., da Fonseca P.C., Morris E.P., Joseph S.K. Calcium-dependent conformational changes in inositol trisphosphate receptors. J. Biol. Chem. 2010, 285:25085-25093.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 25085-25093
-
-
Anyatonwu, G.1
Khan, M.T.2
Schug, Z.T.3
da Fonseca, P.C.4
Morris, E.P.5
Joseph, S.K.6
-
92
-
-
33747667565
-
The role of the S4-S5 linker and C-terminal tail in inositol 1,4,5-trisphosphate receptor function
-
Schug Z.T., Joseph S.K. The role of the S4-S5 linker and C-terminal tail in inositol 1,4,5-trisphosphate receptor function. J. Biol. Chem. 2006, 281:24431-24440.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 24431-24440
-
-
Schug, Z.T.1
Joseph, S.K.2
-
93
-
-
48749088397
-
2+ channel, is a novel substrate of polo-like kinase 1 in eggs
-
2+ channel, is a novel substrate of polo-like kinase 1 in eggs. Dev. Biol. 2008, 320:402-413.
-
(2008)
Dev. Biol.
, vol.320
, pp. 402-413
-
-
Ito, J.1
Yoon, S.Y.2
Lee, B.3
Vanderheyden, V.4
Vermassen, E.5
Wojcikiewicz, R.6
Alfandari, D.7
De Smedt, H.8
Parys, J.B.9
Fissore, R.A.10
-
94
-
-
67649088035
-
Regulation of inositol 1,4,5-trisphosphate receptor type 1 function during oocyte maturation by MPM-2 phosphorylation
-
Vanderheyden V., Wakai T., Bultynck G., De Smedt H., Parys J.B., Fissore R.A. Regulation of inositol 1,4,5-trisphosphate receptor type 1 function during oocyte maturation by MPM-2 phosphorylation. Cell Calcium 2009, 46:56-64.
-
(2009)
Cell Calcium
, vol.46
, pp. 56-64
-
-
Vanderheyden, V.1
Wakai, T.2
Bultynck, G.3
De Smedt, H.4
Parys, J.B.5
Fissore, R.A.6
-
95
-
-
0037439746
-
Modulation of type 1 inositol (1,4,5)-trisphosphate receptor function by protein kinase a and protein phosphatase 1alpha
-
Tang T.S., Tu H., Wang Z., Bezprozvanny I. Modulation of type 1 inositol (1,4,5)-trisphosphate receptor function by protein kinase a and protein phosphatase 1alpha. J. Neurosci. 2003, 23:403-415.
-
(2003)
J. Neurosci.
, vol.23
, pp. 403-415
-
-
Tang, T.S.1
Tu, H.2
Wang, Z.3
Bezprozvanny, I.4
-
97
-
-
33344471431
-
4.1N binding regions of inositol 1,4,5-trisphosphate receptor type 1
-
Fukatsu K., Bannai H., Inoue T., Mikoshiba K. 4.1N binding regions of inositol 1,4,5-trisphosphate receptor type 1. Biochem. Biophys. Res. Commun. 2006, 342:573-576.
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.342
, pp. 573-576
-
-
Fukatsu, K.1
Bannai, H.2
Inoue, T.3
Mikoshiba, K.4
-
98
-
-
0041963057
-
Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1
-
Tang T.S., Tu H., Chan E.Y., Maximov A., Wang Z., Wellington C.L., Hayden M.R., Bezprozvanny I. Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1. Neuron 2003, 39:227-239.
-
(2003)
Neuron
, vol.39
, pp. 227-239
-
-
Tang, T.S.1
Tu, H.2
Chan, E.Y.3
Maximov, A.4
Wang, Z.5
Wellington, C.L.6
Hayden, M.R.7
Bezprozvanny, I.8
-
99
-
-
34248584090
-
Inositol trisphosphate receptor Ca2+ release channels
-
Foskett J.K., White C., Cheung K.H., Mak D.O. Inositol trisphosphate receptor Ca2+ release channels. Physiol. Rev. 2007, 87:593-658.
-
(2007)
Physiol. Rev.
, vol.87
, pp. 593-658
-
-
Foskett, J.K.1
White, C.2
Cheung, K.H.3
Mak, D.O.4
-
100
-
-
84859884275
-
Inositol 1,4,5-trisphosphate and its receptors
-
Parys J.B., De Smedt H. Inositol 1,4,5-trisphosphate and its receptors. Adv. Exp. Med. Biol. 2012, 740:255-279.
-
(2012)
Adv. Exp. Med. Biol.
, vol.740
, pp. 255-279
-
-
Parys, J.B.1
De Smedt, H.2
-
101
-
-
0032487674
-
Type III InsP3 receptor channel stays open in the presence of increased calcium
-
Hagar R.E., Burgstahler A.D., Nathanson M.H., Ehrlich B.E. Type III InsP3 receptor channel stays open in the presence of increased calcium. Nature 1998, 396:81-84.
-
(1998)
Nature
, vol.396
, pp. 81-84
-
-
Hagar, R.E.1
Burgstahler, A.D.2
Nathanson, M.H.3
Ehrlich, B.E.4
-
102
-
-
0026432666
-
Bell-shaped calcium-response curves of Ins(1,4,5)P3- and calcium-gated channels from endoplasmic reticulum of cerebellum
-
Bezprozvanny I., Watras J., Ehrlich B.E. Bell-shaped calcium-response curves of Ins(1,4,5)P3- and calcium-gated channels from endoplasmic reticulum of cerebellum. Nature 1991, 351:751-754.
-
(1991)
Nature
, vol.351
, pp. 751-754
-
-
Bezprozvanny, I.1
Watras, J.2
Ehrlich, B.E.3
-
105
-
-
0032502710
-
3 receptor in 16HBE14o- bronchial mucosal cells
-
3 receptor in 16HBE14o- bronchial mucosal cells. J. Biol. Chem. 1998, 273:8983-8986.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 8983-8986
-
-
Missiaen, L.1
Parys, J.B.2
Sienaert, I.3
Maes, K.4
Kunzelmann, K.5
Takahashi, M.6
Tanzawa, K.7
De Smedt, H.8
-
106
-
-
79251605753
-
Positive regulation of inositol 1,4,5-trisphosphate-induced Ca2+ release by mammalian target of rapamycin (mTOR) in RINm5F cells
-
Fregeau M.O., Regimbald-Dumas Y., Guillemette G. Positive regulation of inositol 1,4,5-trisphosphate-induced Ca2+ release by mammalian target of rapamycin (mTOR) in RINm5F cells. J. Cell. Biochem. 2011, 112:723-733.
-
(2011)
J. Cell. Biochem.
, vol.112
, pp. 723-733
-
-
Fregeau, M.O.1
Regimbald-Dumas, Y.2
Guillemette, G.3
-
107
-
-
64849113485
-
Control of mitochondrial apoptosis by the Bcl-2 family
-
Brunelle J.K., Letai A. Control of mitochondrial apoptosis by the Bcl-2 family. J. Cell Sci. 2009, 122:437-441.
-
(2009)
J. Cell Sci.
, vol.122
, pp. 437-441
-
-
Brunelle, J.K.1
Letai, A.2
-
108
-
-
75949105922
-
The BCL-2 family reunion
-
Chipuk J.E., Moldoveanu T., Llambi F., Parsons M.J., Green D.R. The BCL-2 family reunion. Mol. Cell 2010, 37:299-310.
-
(2010)
Mol. Cell
, vol.37
, pp. 299-310
-
-
Chipuk, J.E.1
Moldoveanu, T.2
Llambi, F.3
Parsons, M.J.4
Green, D.R.5
-
109
-
-
0021829149
-
Clustering of breakpoints on chromosome 11 in human B-cell neoplasms with the t(11;14) chromosome translocation
-
Tsujimoto Y., Jaffe E., Cossman J., Gorham J., Nowell P.C., Croce C.M. Clustering of breakpoints on chromosome 11 in human B-cell neoplasms with the t(11;14) chromosome translocation. Nature 1985, 315:340-343.
-
(1985)
Nature
, vol.315
, pp. 340-343
-
-
Tsujimoto, Y.1
Jaffe, E.2
Cossman, J.3
Gorham, J.4
Nowell, P.C.5
Croce, C.M.6
-
110
-
-
0023918737
-
The bcl-2 gene is rearranged in many diffuse B-cell lymphomas
-
Aisenberg A.C., Wilkes B.M., Jacobson J.O. The bcl-2 gene is rearranged in many diffuse B-cell lymphomas. Blood 1988, 71:969-972.
-
(1988)
Blood
, vol.71
, pp. 969-972
-
-
Aisenberg, A.C.1
Wilkes, B.M.2
Jacobson, J.O.3
-
111
-
-
0025804272
-
Oncogene rearrangements in chronic B-cell leukemia
-
Raghoebier S., van Krieken J.H., Kluin-Nelemans J.C., Gillis A., van Ommen G.J., Ginsberg A.M., Raffeld M., Kluin P.M. Oncogene rearrangements in chronic B-cell leukemia. Blood 1991, 77:1560-1564.
-
(1991)
Blood
, vol.77
, pp. 1560-1564
-
-
Raghoebier, S.1
van Krieken, J.H.2
Kluin-Nelemans, J.C.3
Gillis, A.4
van Ommen, G.J.5
Ginsberg, A.M.6
Raffeld, M.7
Kluin, P.M.8
-
112
-
-
0028353144
-
BCL2 translocations in leukemias of mature B cells
-
Dyer M.J., Zani V.J., Lu W.Z., O'Byrne A., Mould S., Chapman R., Heward J.M., Kayano H., Jadayel D., Matutes E., et al. BCL2 translocations in leukemias of mature B cells. Blood 1994, 83:3682-3688.
-
(1994)
Blood
, vol.83
, pp. 3682-3688
-
-
Dyer, M.J.1
Zani, V.J.2
Lu, W.Z.3
O'Byrne, A.4
Mould, S.5
Chapman, R.6
Heward, J.M.7
Kayano, H.8
Jadayel, D.9
Matutes, E.10
-
113
-
-
0029850883
-
Chronic lymphocytic leukemia
-
Dighiero G., Binet J.L. Chronic lymphocytic leukemia. Hematol. Cell Ther. 1996, 38(Suppl. 2):S41-S61.
-
(1996)
Hematol. Cell Ther.
, vol.38
, Issue.SUPPL. 2
-
-
Dighiero, G.1
Binet, J.L.2
-
114
-
-
0000634556
-
Variant translocation of the bcl-2 gene to immunoglobulin lambda light chain gene in chronic lymphocytic leukemia
-
Adachi M., Cossman J., Longo D., Croce C.M., Tsujimoto Y. Variant translocation of the bcl-2 gene to immunoglobulin lambda light chain gene in chronic lymphocytic leukemia. Proc. Natl. Acad. Sci. U.S.A. 1989, 86:2771-2774.
-
(1989)
Proc. Natl. Acad. Sci. U.S.A.
, vol.86
, pp. 2771-2774
-
-
Adachi, M.1
Cossman, J.2
Longo, D.3
Croce, C.M.4
Tsujimoto, Y.5
-
115
-
-
27244434788
-
A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemia
-
Calin G.A., Ferracin M., Cimmino A., Di Leva G., Shimizu M., Wojcik S.E., Iorio M.V., Visone R., Sever N.I., Fabbri M., Iuliano R., Palumbo T., Pichiorri F., Roldo C., Garzon R., Sevignani C., Rassenti L., Alder H., Volinia S., Liu C.G., Kipps T.J., Negrini M., Croce C.M. A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemia. N. Engl. J. Med. 2005, 353:1793-1801.
-
(2005)
N. Engl. J. Med.
, vol.353
, pp. 1793-1801
-
-
Calin, G.A.1
Ferracin, M.2
Cimmino, A.3
Di Leva, G.4
Shimizu, M.5
Wojcik, S.E.6
Iorio, M.V.7
Visone, R.8
Sever, N.I.9
Fabbri, M.10
Iuliano, R.11
Palumbo, T.12
Pichiorri, F.13
Roldo, C.14
Garzon, R.15
Sevignani, C.16
Rassenti, L.17
Alder, H.18
Volinia, S.19
Liu, C.G.20
Kipps, T.J.21
Negrini, M.22
Croce, C.M.23
more..
-
116
-
-
21744433241
-
Genetics and molecular biology of chronic lymphocytic leukemia
-
Carney D.A., Wierda W.G. Genetics and molecular biology of chronic lymphocytic leukemia. Curr. Treat. Options Oncol. 2005, 6:215-225.
-
(2005)
Curr. Treat. Options Oncol.
, vol.6
, pp. 215-225
-
-
Carney, D.A.1
Wierda, W.G.2
-
117
-
-
34547854381
-
The role of microRNA and other non-coding RNA in the pathogenesis of chronic lymphocytic leukemia
-
Calin G.A., Pekarsky Y., Croce C.M. The role of microRNA and other non-coding RNA in the pathogenesis of chronic lymphocytic leukemia. Best Pract. Res. Clin. Haematol. 2007, 20:425-437.
-
(2007)
Best Pract. Res. Clin. Haematol.
, vol.20
, pp. 425-437
-
-
Calin, G.A.1
Pekarsky, Y.2
Croce, C.M.3
-
118
-
-
80051761743
-
The role of Bcl-2 and its pro-survival relatives in tumourigenesis and cancer therapy
-
Kelly P.N., Strasser A. The role of Bcl-2 and its pro-survival relatives in tumourigenesis and cancer therapy. Cell Death Differ. 2011, 18:1414-1424.
-
(2011)
Cell Death Differ.
, vol.18
, pp. 1414-1424
-
-
Kelly, P.N.1
Strasser, A.2
-
120
-
-
2642555698
-
The role of Bcl-2 family members in non-small cell lung cancer
-
Daniel J.C., Smythe W.R. The role of Bcl-2 family members in non-small cell lung cancer. Semin. Thorac. Cardiovasc. Surg. 2004, 16:19-27.
-
(2004)
Semin. Thorac. Cardiovasc. Surg.
, vol.16
, pp. 19-27
-
-
Daniel, J.C.1
Smythe, W.R.2
-
121
-
-
38549145044
-
Diagnosing and exploiting cancer's addiction to blocks in apoptosis
-
Letai A.G. Diagnosing and exploiting cancer's addiction to blocks in apoptosis. Nat. Rev. Cancer 2008, 8:121-132.
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 121-132
-
-
Letai, A.G.1
-
122
-
-
77949881804
-
Voltage-dependent anion channel 1-based peptides interact with Bcl-2 to prevent antiapoptotic activity
-
Arbel N., Shoshan-Barmatz V. Voltage-dependent anion channel 1-based peptides interact with Bcl-2 to prevent antiapoptotic activity. J. Biol. Chem. 2010, 285:6053-6062.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 6053-6062
-
-
Arbel, N.1
Shoshan-Barmatz, V.2
-
123
-
-
84855658120
-
2+ signals to mitochondria
-
2+ signals to mitochondria. Cell Death Differ. 2012, 19:267-273.
-
(2012)
Cell Death Differ.
, vol.19
, pp. 267-273
-
-
De Stefani, D.1
Bononi, A.2
Romagnoli, A.3
Messina, A.4
De Pinto, V.5
Pinton, P.6
Rizzuto, R.7
-
125
-
-
0029948611
-
Bcl-2 inhibits hydrogen peroxide-induced ER Ca2+ pool depletion
-
Distelhorst C.W., Lam M., McCormick T.S. Bcl-2 inhibits hydrogen peroxide-induced ER Ca2+ pool depletion. Oncogene 1996, 12:2051-2055.
-
(1996)
Oncogene
, vol.12
, pp. 2051-2055
-
-
Distelhorst, C.W.1
Lam, M.2
McCormick, T.S.3
-
126
-
-
0346250162
-
Regulation of apoptosis by endoplasmic reticulum pathways
-
Breckenridge D.G., Germain M., Mathai J.P., Nguyen M., Shore G.C. Regulation of apoptosis by endoplasmic reticulum pathways. Oncogene 2003, 22:8608-8618.
-
(2003)
Oncogene
, vol.22
, pp. 8608-8618
-
-
Breckenridge, D.G.1
Germain, M.2
Mathai, J.P.3
Nguyen, M.4
Shore, G.C.5
-
127
-
-
2342564508
-
Bcl-2 and calcium: controversy beneath the surface
-
Distelhorst C.W., Shore G.C. Bcl-2 and calcium: controversy beneath the surface. Oncogene 2004, 23:2875-2880.
-
(2004)
Oncogene
, vol.23
, pp. 2875-2880
-
-
Distelhorst, C.W.1
Shore, G.C.2
-
128
-
-
0034610995
-
2+ influx in Bcl-2-overexpressing cells
-
2+ influx in Bcl-2-overexpressing cells. J. Cell Biol. 2000, 148:857-862.
-
(2000)
J. Cell Biol.
, vol.148
, pp. 857-862
-
-
Pinton, P.1
Ferrari, D.2
Magalhaes, P.3
Schulze-Osthoff, K.4
Di-Virgilio, F.5
Pozzan, T.6
Rizzuto, R.7
-
129
-
-
0035355341
-
The Ca2+ concentration of the endoplasmic reticulum is a key determinant of ceramide-induced apoptosis: significance for the molecular mechanism of Bcl-2 action
-
Pinton P., Ferrari D., Rapizzi E., Di Virgilio F., Pozzan T., Rizzuto R. The Ca2+ concentration of the endoplasmic reticulum is a key determinant of ceramide-induced apoptosis: significance for the molecular mechanism of Bcl-2 action. EMBO J. 2001, 20:2690-2701.
-
(2001)
EMBO J.
, vol.20
, pp. 2690-2701
-
-
Pinton, P.1
Ferrari, D.2
Rapizzi, E.3
Di Virgilio, F.4
Pozzan, T.5
Rizzuto, R.6
-
130
-
-
0037418843
-
2+: a control point for apoptosis
-
2+: a control point for apoptosis. Science 2003, 300:135-139.
-
(2003)
Science
, vol.300
, pp. 135-139
-
-
Scorrano, L.1
Oakes, S.A.2
Opferman, J.T.3
Cheng, E.H.4
Sorcinelli, M.D.5
Pozzan, T.6
Korsmeyer, S.J.7
-
131
-
-
10644234677
-
Bcl-2-mediated alterations in endoplasmic reticulum Ca2+ analyzed with an improved genetically encoded fluorescent sensor
-
Palmer A.E., Jin C., Reed J.C., Tsien R.Y. Bcl-2-mediated alterations in endoplasmic reticulum Ca2+ analyzed with an improved genetically encoded fluorescent sensor. Proc. Natl. Acad. Sci. U. S. A. 2004, 101:17404-17409.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 17404-17409
-
-
Palmer, A.E.1
Jin, C.2
Reed, J.C.3
Tsien, R.Y.4
-
132
-
-
11844284861
-
Proapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulum
-
Oakes S.A., Scorrano L., Opferman J.T., Bassik M.C., Nishino M., Pozzan T., Korsmeyer S.J. Proapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulum. Proc. Natl. Acad. Sci. U.S.A. 2005, 102:105-110.
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 105-110
-
-
Oakes, S.A.1
Scorrano, L.2
Opferman, J.T.3
Bassik, M.C.4
Nishino, M.5
Pozzan, T.6
Korsmeyer, S.J.7
-
133
-
-
34547617018
-
Apoptosis regulation by Bcl-x(L) modulation of mammalian inositol 1,4,5-trisphosphate receptor channel isoform gating
-
Li C., Wang X., Vais H., Thompson C.B., Foskett J.K., White C. Apoptosis regulation by Bcl-x(L) modulation of mammalian inositol 1,4,5-trisphosphate receptor channel isoform gating. Proc. Natl. Acad. Sci. U.S.A. 2007, 104:12565-12570.
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 12565-12570
-
-
Li, C.1
Wang, X.2
Vais, H.3
Thompson, C.B.4
Foskett, J.K.5
White, C.6
-
135
-
-
77958144582
-
Alternative functions of the BCL-2 protein family at the endoplasmic reticulum
-
Rojas-Rivera D., Caballero B., Zamorano S., Lisbona F., Hetz C. Alternative functions of the BCL-2 protein family at the endoplasmic reticulum. Adv. Exp. Med. Biol. 2010, 687:33-47.
-
(2010)
Adv. Exp. Med. Biol.
, vol.687
, pp. 33-47
-
-
Rojas-Rivera, D.1
Caballero, B.2
Zamorano, S.3
Lisbona, F.4
Hetz, C.5
-
136
-
-
71949101502
-
Xanthohumol activates the proapoptotic arm of the unfolded protein response in chronic lymphocytic leukemia
-
Lust S., Vanhoecke B., Van Gele M., Boelens J., Van Melckebeke H., Kaileh M., Vanden Berghe W., Haegeman G., Philippe J., Bracke M., Offner F. Xanthohumol activates the proapoptotic arm of the unfolded protein response in chronic lymphocytic leukemia. Anticancer Res. 2009, 29:3797-3805.
-
(2009)
Anticancer Res.
, vol.29
, pp. 3797-3805
-
-
Lust, S.1
Vanhoecke, B.2
Van Gele, M.3
Boelens, J.4
Van Melckebeke, H.5
Kaileh, M.6
Vanden Berghe, W.7
Haegeman, G.8
Philippe, J.9
Bracke, M.10
Offner, F.11
-
137
-
-
84870911687
-
ER stress in diffuse large B cell lymphoma: GRP94 is a possible biomarker in germinal center versus activated B-cell type
-
Boelens J., Jais J.P., Vanhoecke B., Beck I., Van Melckebeke H., Philippe J., Bracke M., Jardin F., Briere J., Leroy K., Offner F., Lust S. ER stress in diffuse large B cell lymphoma: GRP94 is a possible biomarker in germinal center versus activated B-cell type. Leuk. Res. 2012, 37:3-8.
-
(2012)
Leuk. Res.
, vol.37
, pp. 3-8
-
-
Boelens, J.1
Jais, J.P.2
Vanhoecke, B.3
Beck, I.4
Van Melckebeke, H.5
Philippe, J.6
Bracke, M.7
Jardin, F.8
Briere, J.9
Leroy, K.10
Offner, F.11
Lust, S.12
-
138
-
-
3342984659
-
Bcl-2 functionally interacts with inositol 1,4,5-trisphosphate receptors to regulate calcium release from the ER in response to inositol 1,4,5-trisphosphate
-
Chen R., Valencia I., Zhong F., McColl K.S., Roderick H.L., Bootman M.D., Berridge M.J., Conway S.J., Holmes A.B., Mignery G.A., Velez P., Distelhorst C.W. Bcl-2 functionally interacts with inositol 1,4,5-trisphosphate receptors to regulate calcium release from the ER in response to inositol 1,4,5-trisphosphate. J. Cell Biol. 2004, 166:193-203.
-
(2004)
J. Cell Biol.
, vol.166
, pp. 193-203
-
-
Chen, R.1
Valencia, I.2
Zhong, F.3
McColl, K.S.4
Roderick, H.L.5
Bootman, M.D.6
Berridge, M.J.7
Conway, S.J.8
Holmes, A.B.9
Mignery, G.A.10
Velez, P.11
Distelhorst, C.W.12
-
139
-
-
29944435173
-
Bcl-2 differentially regulates Ca2+ signals according to the strength of T cell receptor activation
-
Zhong F., Davis M.C., McColl K.S., Distelhorst C.W. Bcl-2 differentially regulates Ca2+ signals according to the strength of T cell receptor activation. J. Cell Biol. 2006, 172:127-137.
-
(2006)
J. Cell Biol.
, vol.172
, pp. 127-137
-
-
Zhong, F.1
Davis, M.C.2
McColl, K.S.3
Distelhorst, C.W.4
-
140
-
-
47349089719
-
Targeting Bcl-2-IP3 receptor interaction to reverse Bcl-2's inhibition of apoptotic calcium signals
-
Rong Y.P., Aromolaran A.S., Bultynck G., Zhong F., Li X., McColl K., Matsuyama S., Herlitze S., Roderick H.L., Bootman M.D., Mignery G.A., Parys J.B., De Smedt H., Distelhorst C.W. Targeting Bcl-2-IP3 receptor interaction to reverse Bcl-2's inhibition of apoptotic calcium signals. Mol. Cell 2008, 31:255-265.
-
(2008)
Mol. Cell
, vol.31
, pp. 255-265
-
-
Rong, Y.P.1
Aromolaran, A.S.2
Bultynck, G.3
Zhong, F.4
Li, X.5
McColl, K.6
Matsuyama, S.7
Herlitze, S.8
Roderick, H.L.9
Bootman, M.D.10
Mignery, G.A.11
Parys, J.B.12
De Smedt, H.13
Distelhorst, C.W.14
-
143
-
-
70149105706
-
The BH4 domain of Bcl-2 inhibits ER calcium release and apoptosis by binding the regulatory and coupling domain of the IP3 receptor
-
Rong Y.P., Bultynck G., Aromolaran A.S., Zhong F., Parys J.B., De Smedt H., Mignery G.A., Roderick H.L., Bootman M.D., Distelhorst C.W. The BH4 domain of Bcl-2 inhibits ER calcium release and apoptosis by binding the regulatory and coupling domain of the IP3 receptor. Proc. Natl. Acad. Sci. U.S.A. 2009, 106:14397-14402.
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 14397-14402
-
-
Rong, Y.P.1
Bultynck, G.2
Aromolaran, A.S.3
Zhong, F.4
Parys, J.B.5
De Smedt, H.6
Mignery, G.A.7
Roderick, H.L.8
Bootman, M.D.9
Distelhorst, C.W.10
-
144
-
-
79953119371
-
3 receptor interaction
-
3 receptor interaction. Blood 2011, 117:2924-2934.
-
(2011)
Blood
, vol.117
, pp. 2924-2934
-
-
Zhong, F.1
Harr, M.W.2
Bultynck, G.3
Monaco, G.4
Parys, J.B.5
De Smedt, H.6
Rong, Y.P.7
Molitoris, J.K.8
Lam, M.9
Ryder, C.10
Matsuyama, S.11
Distelhorst, C.W.12
-
145
-
-
33646354381
-
Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members
-
Certo M., Del Gaizo Moore V., Nishino M., Wei G., Korsmeyer S., Armstrong S.A., Letai A. Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members. Cancer Cell 2006, 9:351-365.
-
(2006)
Cancer Cell
, vol.9
, pp. 351-365
-
-
Certo, M.1
Del Gaizo Moore, V.2
Nishino, M.3
Wei, G.4
Korsmeyer, S.5
Armstrong, S.A.6
Letai, A.7
-
146
-
-
33845994359
-
Chronic lymphocytic leukemia requires BCL2 to sequester prodeath BIM, explaining sensitivity to BCL2 antagonist ABT-737
-
Del Gaizo Moore V., Brown J.R., Certo M., Love T.M., Novina C.D., Letai A. Chronic lymphocytic leukemia requires BCL2 to sequester prodeath BIM, explaining sensitivity to BCL2 antagonist ABT-737. J. Clin. Invest. 2007, 117:112-121.
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 112-121
-
-
Del Gaizo Moore, V.1
Brown, J.R.2
Certo, M.3
Love, T.M.4
Novina, C.D.5
Letai, A.6
-
147
-
-
34547603628
-
BH3 profiling identifies three distinct classes of apoptotic blocks to predict response to ABT-737 and conventional chemotherapeutic agents
-
Deng J., Carlson N., Takeyama K., Dal Cin P., Shipp M., Letai A. BH3 profiling identifies three distinct classes of apoptotic blocks to predict response to ABT-737 and conventional chemotherapeutic agents. Cancer Cell 2007, 12:171-185.
-
(2007)
Cancer Cell
, vol.12
, pp. 171-185
-
-
Deng, J.1
Carlson, N.2
Takeyama, K.3
Dal Cin, P.4
Shipp, M.5
Letai, A.6
-
148
-
-
82255192310
-
Pretreatment mitochondrial priming correlates with clinical response to cytotoxic chemotherapy
-
Ni Chonghaile T., Sarosiek K.A., Vo T.T., Ryan J.A., Tammareddi A., Moore Vdel G., Deng J., Anderson K.C., Richardson P., Tai Y.T., Mitsiades C.S., Matulonis U.A., Drapkin R., Stone R., Deangelo D.J., McConkey D.J., Sallan S.E., Silverman L., Hirsch M.S., Carrasco D.R., Letai A. Pretreatment mitochondrial priming correlates with clinical response to cytotoxic chemotherapy. Science 2011, 334:1129-1133.
-
(2011)
Science
, vol.334
, pp. 1129-1133
-
-
Ni Chonghaile, T.1
Sarosiek, K.A.2
Vo, T.T.3
Ryan, J.A.4
Tammareddi, A.5
Moore Vdel, G.6
Deng, J.7
Anderson, K.C.8
Richardson, P.9
Tai, Y.T.10
Mitsiades, C.S.11
Matulonis, U.A.12
Drapkin, R.13
Stone, R.14
Deangelo, D.J.15
McConkey, D.J.16
Sallan, S.E.17
Silverman, L.18
Hirsch, M.S.19
Carrasco, D.R.20
Letai, A.21
more..
-
149
-
-
42549144606
-
Bcl-2 protein family members: versatile regulators of calcium signaling in cell survival and apoptosis
-
Rong Y., Distelhorst C.W. Bcl-2 protein family members: versatile regulators of calcium signaling in cell survival and apoptosis. Annu. Rev. Physiol. 2008, 70:73-91.
-
(2008)
Annu. Rev. Physiol.
, vol.70
, pp. 73-91
-
-
Rong, Y.1
Distelhorst, C.W.2
-
150
-
-
79952705597
-
Integrating stress signals at the endoplasmic reticulum: The BCL-2 protein family rheostat
-
Rodriguez D., Rojas-Rivera D., Hetz C. Integrating stress signals at the endoplasmic reticulum: The BCL-2 protein family rheostat. Biochim. Biophys. Acta 2011, 1813:564-574.
-
(2011)
Biochim. Biophys. Acta
, vol.1813
, pp. 564-574
-
-
Rodriguez, D.1
Rojas-Rivera, D.2
Hetz, C.3
-
151
-
-
0031901001
-
BCL-X and the apoptotic machinery of lymphoma cells
-
Xerri L., Hassoun J., Devilard E., Birnbaum D., Birg F. BCL-X and the apoptotic machinery of lymphoma cells. Leuk. Lymphoma 1998, 28:451-458.
-
(1998)
Leuk. Lymphoma
, vol.28
, pp. 451-458
-
-
Xerri, L.1
Hassoun, J.2
Devilard, E.3
Birnbaum, D.4
Birg, F.5
-
152
-
-
79952176416
-
The ASPP interaction network: electrostatic differentiation between pro- and anti-apoptotic proteins
-
Benyamini H., Friedler A. The ASPP interaction network: electrostatic differentiation between pro- and anti-apoptotic proteins. J. Mol. Recognit. 2011, 24:266-274.
-
(2011)
J. Mol. Recognit.
, vol.24
, pp. 266-274
-
-
Benyamini, H.1
Friedler, A.2
-
153
-
-
70349286051
-
New insights into the expanding complexity of the tumor suppressor ASPP2
-
Kampa K.M., Bonin M., Lopez C.D. New insights into the expanding complexity of the tumor suppressor ASPP2. Cell Cycle 2009, 8:2871-2876.
-
(2009)
Cell Cycle
, vol.8
, pp. 2871-2876
-
-
Kampa, K.M.1
Bonin, M.2
Lopez, C.D.3
-
154
-
-
50449091105
-
Molecular basis of the interaction between the antiapoptotic Bcl-2 family proteins and the proapoptotic protein ASPP2
-
Katz C., Benyamini H., Rotem S., Lebendiker M., Danieli T., Iosub A., Refaely H., Dines M., Bronner V., Bravman T., Shalev D.E., Rudiger S., Friedler A. Molecular basis of the interaction between the antiapoptotic Bcl-2 family proteins and the proapoptotic protein ASPP2. Proc. Natl. Acad. Sci. U.S.A. 2008, 105:12277-12282.
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 12277-12282
-
-
Katz, C.1
Benyamini, H.2
Rotem, S.3
Lebendiker, M.4
Danieli, T.5
Iosub, A.6
Refaely, H.7
Dines, M.8
Bronner, V.9
Bravman, T.10
Shalev, D.E.11
Rudiger, S.12
Friedler, A.13
-
155
-
-
84876688640
-
The selective BH4-domain biology of Bcl-2-family members: IP 3 Rs and beyond
-
Monaco G., Vervliet T., Akl H., Bultynck G. The selective BH4-domain biology of Bcl-2-family members: IP 3 Rs and beyond. Cell. Mol. Life Sci. 2012, 1-13.
-
(2012)
Cell. Mol. Life Sci.
, pp. 1-13
-
-
Monaco, G.1
Vervliet, T.2
Akl, H.3
Bultynck, G.4
-
156
-
-
67649405072
-
Insight into the structural basis of pro- and antiapoptotic p53 modulation by ASPP proteins
-
Ahn J., Byeon I.J., Byeon C.H., Gronenborn A.M. Insight into the structural basis of pro- and antiapoptotic p53 modulation by ASPP proteins. J. Biol. Chem. 2009, 284:13812-13822.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 13812-13822
-
-
Ahn, J.1
Byeon, I.J.2
Byeon, C.H.3
Gronenborn, A.M.4
-
157
-
-
33846551682
-
ASPP: a new family of oncogenes and tumour suppressor genes
-
Sullivan A., Lu X. ASPP: a new family of oncogenes and tumour suppressor genes. Br. J. Cancer 2007, 96:196-200.
-
(2007)
Br. J. Cancer
, vol.96
, pp. 196-200
-
-
Sullivan, A.1
Lu, X.2
-
158
-
-
33749610878
-
ASPP2: a gene that controls life and death in vivo
-
Vives V., Slee E.A., Lu X. ASPP2: a gene that controls life and death in vivo. Cell Cycle 2006, 5:2187-2190.
-
(2006)
Cell Cycle
, vol.5
, pp. 2187-2190
-
-
Vives, V.1
Slee, E.A.2
Lu, X.3
-
161
-
-
0037162528
-
2+ homeostasis by altering expression of inositol 1,4,5-trisphosphate receptors
-
2+ homeostasis by altering expression of inositol 1,4,5-trisphosphate receptors. Proc. Natl. Acad. Sci. U.S.A. 2002, 99:9830-9835.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 9830-9835
-
-
Li, C.1
Fox, C.J.2
Master, S.R.3
Bindokas, V.P.4
Chodosh, L.A.5
Thompson, C.B.6
-
162
-
-
84863316405
-
Mediation of the antiapoptotic activity of Bcl-xL protein upon interaction with VDAC1 protein
-
Arbel N., Ben-Hail D., Shoshan-Barmatz V. Mediation of the antiapoptotic activity of Bcl-xL protein upon interaction with VDAC1 protein. J. Biol. Chem. 2012, 287:23152-23161.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 23152-23161
-
-
Arbel, N.1
Ben-Hail, D.2
Shoshan-Barmatz, V.3
-
164
-
-
19944432123
-
Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function
-
Chen L., Willis S.N., Wei A., Smith B.J., Fletcher J.I., Hinds M.G., Colman P.M., Day C.L., Adams J.M., Huang D.C. Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function. Mol. Cell 2005, 17:393-403.
-
(2005)
Mol. Cell
, vol.17
, pp. 393-403
-
-
Chen, L.1
Willis, S.N.2
Wei, A.3
Smith, B.J.4
Fletcher, J.I.5
Hinds, M.G.6
Colman, P.M.7
Day, C.L.8
Adams, J.M.9
Huang, D.C.10
-
165
-
-
0036659905
-
Antisense strategy shows that Mcl-1 rather than Bcl-2 or Bcl-x(L) is an essential survival protein of human myeloma cells
-
Derenne S., Monia B., Dean N.M., Taylor J.K., Rapp M.J., Harousseau J.L., Bataille R., Amiot M. Antisense strategy shows that Mcl-1 rather than Bcl-2 or Bcl-x(L) is an essential survival protein of human myeloma cells. Blood 2002, 100:194-199.
-
(2002)
Blood
, vol.100
, pp. 194-199
-
-
Derenne, S.1
Monia, B.2
Dean, N.M.3
Taylor, J.K.4
Rapp, M.J.5
Harousseau, J.L.6
Bataille, R.7
Amiot, M.8
-
166
-
-
0036080889
-
Overexpression of Mcl-1 in anaplastic large cell lymphoma cell lines and tumors
-
Rassidakis G.Z., Lai R., McDonnell T.J., Cabanillas F., Sarris A.H., Medeiros L.J. Overexpression of Mcl-1 in anaplastic large cell lymphoma cell lines and tumors. Am. J. Pathol. 2002, 160:2309-2310.
-
(2002)
Am. J. Pathol.
, vol.160
, pp. 2309-2310
-
-
Rassidakis, G.Z.1
Lai, R.2
McDonnell, T.J.3
Cabanillas, F.4
Sarris, A.H.5
Medeiros, L.J.6
-
167
-
-
4444365042
-
MCL-1 expression in B-cell non-Hodgkin's lymphomas
-
Cho-Vega J.H., Rassidakis G.Z., Admirand J.H., Oyarzo M., Ramalingam P., Paraguya A., McDonnell T.J., Amin H.M., Medeiros L.J. MCL-1 expression in B-cell non-Hodgkin's lymphomas. Hum. Pathol. 2004, 35:1095-1100.
-
(2004)
Hum. Pathol.
, vol.35
, pp. 1095-1100
-
-
Cho-Vega, J.H.1
Rassidakis, G.Z.2
Admirand, J.H.3
Oyarzo, M.4
Ramalingam, P.5
Paraguya, A.6
McDonnell, T.J.7
Amin, H.M.8
Medeiros, L.J.9
-
168
-
-
20144388297
-
Identification of mcl-1 as a BCR/ABL-dependent target in chronic myeloid leukemia (CML): evidence for cooperative antileukemic effects of imatinib and mcl-1 antisense oligonucleotides
-
Aichberger K.J., Mayerhofer M., Krauth M.T., Skvara H., Florian S., Sonneck K., Akgul C., Derdak S., Pickl W.F., Wacheck V., Selzer E., Monia B.P., Moriggl R., Valent P., Sillaber C. Identification of mcl-1 as a BCR/ABL-dependent target in chronic myeloid leukemia (CML): evidence for cooperative antileukemic effects of imatinib and mcl-1 antisense oligonucleotides. Blood 2005, 105:3303-3311.
-
(2005)
Blood
, vol.105
, pp. 3303-3311
-
-
Aichberger, K.J.1
Mayerhofer, M.2
Krauth, M.T.3
Skvara, H.4
Florian, S.5
Sonneck, K.6
Akgul, C.7
Derdak, S.8
Pickl, W.F.9
Wacheck, V.10
Selzer, E.11
Monia, B.P.12
Moriggl, R.13
Valent, P.14
Sillaber, C.15
-
169
-
-
28844437366
-
Mcl-1 overexpression in hepatocellular carcinoma: a potential target for antisense therapy
-
Sieghart W., Losert D., Strommer S., Cejka D., Schmid K., Rasoul-Rockenschaub S., Bodingbauer M., Crevenna R., Monia B.P., Peck-Radosavljevic M., Wacheck V. Mcl-1 overexpression in hepatocellular carcinoma: a potential target for antisense therapy. J. Hepatol. 2006, 44:151-157.
-
(2006)
J. Hepatol.
, vol.44
, pp. 151-157
-
-
Sieghart, W.1
Losert, D.2
Strommer, S.3
Cejka, D.4
Schmid, K.5
Rasoul-Rockenschaub, S.6
Bodingbauer, M.7
Crevenna, R.8
Monia, B.P.9
Peck-Radosavljevic, M.10
Wacheck, V.11
-
170
-
-
67349136004
-
Mcl-1 is a potential therapeutic target in multiple types of cancer
-
Akgul C. Mcl-1 is a potential therapeutic target in multiple types of cancer. Cell. Mol. Life Sci. 2009, 66:1326-1336.
-
(2009)
Cell. Mol. Life Sci.
, vol.66
, pp. 1326-1336
-
-
Akgul, C.1
-
171
-
-
84869050209
-
A novel cellular stress response characterised by a rapid reorganisation of membranes of the endoplasmic reticulum
-
Varadarajan S., Bampton E.T., Smalley J.L., Tanaka K., Caves R.E., Butterworth M., Wei J., Pellecchia M., Mitcheson J., Gant T.W., Dinsdale D., Cohen G.M. A novel cellular stress response characterised by a rapid reorganisation of membranes of the endoplasmic reticulum. Cell Death Differ. 2012, 19:1896-1907.
-
(2012)
Cell Death Differ.
, vol.19
, pp. 1896-1907
-
-
Varadarajan, S.1
Bampton, E.T.2
Smalley, J.L.3
Tanaka, K.4
Caves, R.E.5
Butterworth, M.6
Wei, J.7
Pellecchia, M.8
Mitcheson, J.9
Gant, T.W.10
Dinsdale, D.11
Cohen, G.M.12
-
172
-
-
84869012711
-
The ER in 4D: a novel stress pathway controlling endoplasmic reticulum membrane remodeling
-
Urra H., Hetz C. The ER in 4D: a novel stress pathway controlling endoplasmic reticulum membrane remodeling. Cell Death Differ. 2012, 19:1893-1895.
-
(2012)
Cell Death Differ.
, vol.19
, pp. 1893-1895
-
-
Urra, H.1
Hetz, C.2
-
173
-
-
31644442034
-
2+-signaling complexes and Ca2+ regulation in secretory and muscle cells from PERK-knockout mice
-
2+-signaling complexes and Ca2+ regulation in secretory and muscle cells from PERK-knockout mice. J. Cell Sci. 2006, 119:153-161.
-
(2006)
J. Cell Sci.
, vol.119
, pp. 153-161
-
-
Huang, G.1
Yao, J.2
Zeng, W.3
Mizuno, Y.4
Kamm, K.E.5
Stull, J.T.6
Harding, H.P.7
Ron, D.8
Muallem, S.9
-
174
-
-
0031993255
-
Bax inhibitor-1, a mammalian apoptosis suppressor identified by functional screening in yeast
-
Xu Q., Reed J.C. Bax inhibitor-1, a mammalian apoptosis suppressor identified by functional screening in yeast. Mol. Cell 1998, 1:337-346.
-
(1998)
Mol. Cell
, vol.1
, pp. 337-346
-
-
Xu, Q.1
Reed, J.C.2
-
175
-
-
42049114828
-
The Bax Inhibitor-1 (BI-1) family in apoptosis and tumorigenesis
-
Reimers K., Choi C.Y., Bucan V., Vogt P.M. The Bax Inhibitor-1 (BI-1) family in apoptosis and tumorigenesis. Curr. Mol. Med. 2008, 8:148-156.
-
(2008)
Curr. Mol. Med.
, vol.8
, pp. 148-156
-
-
Reimers, K.1
Choi, C.Y.2
Bucan, V.3
Vogt, P.M.4
-
176
-
-
79957603445
-
Bax inhibitor 1 in apoptosis and disease
-
Robinson K.S., Clements A., Williams A.C., Berger C.N., Frankel G. Bax inhibitor 1 in apoptosis and disease. Oncogene 2011, 30:2391-2400.
-
(2011)
Oncogene
, vol.30
, pp. 2391-2400
-
-
Robinson, K.S.1
Clements, A.2
Williams, A.C.3
Berger, C.N.4
Frankel, G.5
-
177
-
-
0036498025
-
Analysis of the antibody repertoire of astrocytoma patients against antigens expressed by gliomas
-
Schmits R., Cochlovius B., Treitz G., Regitz E., Ketter R., Preuss K.D., Romeike B.F., Pfreundschuh M. Analysis of the antibody repertoire of astrocytoma patients against antigens expressed by gliomas. Int. J. Cancer 2002, 98:73-77.
-
(2002)
Int. J. Cancer
, vol.98
, pp. 73-77
-
-
Schmits, R.1
Cochlovius, B.2
Treitz, G.3
Regitz, E.4
Ketter, R.5
Preuss, K.D.6
Romeike, B.F.7
Pfreundschuh, M.8
-
178
-
-
0042847060
-
Bax inhibitor-1 is overexpressed in prostate cancer and its specific down-regulation by RNA interference leads to cell death in human prostate carcinoma cells
-
Grzmil M., Thelen P., Hemmerlein B., Schweyer S., Voigt S., Mury D., Burfeind P. Bax inhibitor-1 is overexpressed in prostate cancer and its specific down-regulation by RNA interference leads to cell death in human prostate carcinoma cells. Am. J. Pathol. 2003, 163:543-552.
-
(2003)
Am. J. Pathol.
, vol.163
, pp. 543-552
-
-
Grzmil, M.1
Thelen, P.2
Hemmerlein, B.3
Schweyer, S.4
Voigt, S.5
Mury, D.6
Burfeind, P.7
-
179
-
-
32244446318
-
Expression and functional analysis of Bax inhibitor-1 in human breast cancer cells
-
Grzmil M., Kaulfuss S., Thelen P., Hemmerlein B., Schweyer S., Obenauer S., Kang T.W., Burfeind P. Expression and functional analysis of Bax inhibitor-1 in human breast cancer cells. J. Pathol. 2006, 208:340-349.
-
(2006)
J. Pathol.
, vol.208
, pp. 340-349
-
-
Grzmil, M.1
Kaulfuss, S.2
Thelen, P.3
Hemmerlein, B.4
Schweyer, S.5
Obenauer, S.6
Kang, T.W.7
Burfeind, P.8
-
180
-
-
31544470384
-
Expression of the Bax inhibitor-1 gene in pulmonary adenocarcinoma
-
Tanaka R., Ishiyama T., Uchihara T., Inadome Y., Iijima T., Morishita Y., Kano J., Goya T., Noguchi M. Expression of the Bax inhibitor-1 gene in pulmonary adenocarcinoma. Cancer 2006, 106:648-653.
-
(2006)
Cancer
, vol.106
, pp. 648-653
-
-
Tanaka, R.1
Ishiyama, T.2
Uchihara, T.3
Inadome, Y.4
Iijima, T.5
Morishita, Y.6
Kano, J.7
Goya, T.8
Noguchi, M.9
-
181
-
-
33747638133
-
Cross-species hybridization of woodchuck hepatitis virus-induced hepatocellular carcinoma using human oligonucleotide microarrays
-
Anderson P.W., Tennant B.C., Lee Z. Cross-species hybridization of woodchuck hepatitis virus-induced hepatocellular carcinoma using human oligonucleotide microarrays. World J. Gastroenterol. 2006, 12:4646-4651.
-
(2006)
World J. Gastroenterol.
, vol.12
, pp. 4646-4651
-
-
Anderson, P.W.1
Tennant, B.C.2
Lee, Z.3
-
182
-
-
73449089738
-
Bax inhibitor-1 mediates apoptosis-resistance in human nasopharyngeal carcinoma cells
-
Zhang M., Li X., Zhang Y., Zhou K. Bax inhibitor-1 mediates apoptosis-resistance in human nasopharyngeal carcinoma cells. Mol. Cell. Biochem. 2010, 333:1-7.
-
(2010)
Mol. Cell. Biochem.
, vol.333
, pp. 1-7
-
-
Zhang, M.1
Li, X.2
Zhang, Y.3
Zhou, K.4
-
183
-
-
77950865511
-
BAX inhibitor-1 enhances cancer metastasis by altering glucose metabolism and activating the sodium-hydrogen exchanger: the alteration of mitochondrial function
-
Lee G.H., Yan C., Shin S.J., Hong S.C., Ahn T., Moon A., Park S.J., Lee Y.C., Yoo W.H., Kim H.T., Kim D.S., Chae S.W., Kim H.R., Chae H.J. BAX inhibitor-1 enhances cancer metastasis by altering glucose metabolism and activating the sodium-hydrogen exchanger: the alteration of mitochondrial function. Oncogene 2010, 29:2130-2141.
-
(2010)
Oncogene
, vol.29
, pp. 2130-2141
-
-
Lee, G.H.1
Yan, C.2
Shin, S.J.3
Hong, S.C.4
Ahn, T.5
Moon, A.6
Park, S.J.7
Lee, Y.C.8
Yoo, W.H.9
Kim, H.T.10
Kim, D.S.11
Chae, S.W.12
Kim, H.R.13
Chae, H.J.14
-
184
-
-
79960907709
-
An acidic pH environment increases cell death and pro-inflammatory cytokine release in osteoblasts: the involvement of BAX inhibitor-1
-
Lee G.H., Hwang J.D., Choi J.Y., Park H.J., Cho J.Y., Kim K.W., Chae H.J., Kim H.R. An acidic pH environment increases cell death and pro-inflammatory cytokine release in osteoblasts: the involvement of BAX inhibitor-1. Int. J. Biochem. Cell Biol. 2011, 43:1305-1317.
-
(2011)
Int. J. Biochem. Cell Biol.
, vol.43
, pp. 1305-1317
-
-
Lee, G.H.1
Hwang, J.D.2
Choi, J.Y.3
Park, H.J.4
Cho, J.Y.5
Kim, K.W.6
Chae, H.J.7
Kim, H.R.8
-
185
-
-
77949355135
-
Bax inhibitor 1 increases cell adhesion through actin polymerization: involvement of calcium and actin binding
-
Lee G.H., Ahn T., Kim D.S., Park S.J., Lee Y.C., Yoo W.H., Jung S.J., Yang J.S., Kim S., Muhlrad A., Seo Y.R., Chae S.W., Kim H.R., Chae H.J. Bax inhibitor 1 increases cell adhesion through actin polymerization: involvement of calcium and actin binding. Mol. Cell. Biol. 2010, 30:1800-1813.
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 1800-1813
-
-
Lee, G.H.1
Ahn, T.2
Kim, D.S.3
Park, S.J.4
Lee, Y.C.5
Yoo, W.H.6
Jung, S.J.7
Yang, J.S.8
Kim, S.9
Muhlrad, A.10
Seo, Y.R.11
Chae, S.W.12
Kim, H.R.13
Chae, H.J.14
-
186
-
-
80052621332
-
The ancient cell death suppressor BAX inhibitor-1
-
Henke N., Lisak D.A., Schneider L., Habicht J., Pergande M., Methner A. The ancient cell death suppressor BAX inhibitor-1. Cell Calcium 2011, 50:251-260.
-
(2011)
Cell Calcium
, vol.50
, pp. 251-260
-
-
Henke, N.1
Lisak, D.A.2
Schneider, L.3
Habicht, J.4
Pergande, M.5
Methner, A.6
-
187
-
-
84865743733
-
Bax Inhibitor-1 is a novel IP3 receptor-interacting and -sensitizing protein
-
Kiviluoto S., Schneider L., Luyten T., Vervliet T., Missiaen L., De Smedt H., Parys J., Methner A., Bultynck G. Bax Inhibitor-1 is a novel IP3 receptor-interacting and -sensitizing protein. Cell Death Dis. 2012, 3:e367.
-
(2012)
Cell Death Dis.
, vol.3
-
-
Kiviluoto, S.1
Schneider, L.2
Luyten, T.3
Vervliet, T.4
Missiaen, L.5
De Smedt, H.6
Parys, J.7
Methner, A.8
Bultynck, G.9
-
188
-
-
84861122472
-
2+-mediated bioenergetics to promote autophagy
-
2+-mediated bioenergetics to promote autophagy. Genes Dev. 2012, 26:1041-1054.
-
(2012)
Genes Dev.
, vol.26
, pp. 1041-1054
-
-
Sano, R.1
Hou, Y.C.2
Hedvat, M.3
Correa, R.G.4
Shu, C.W.5
Krajewska, M.6
Diaz, P.W.7
Tamble, C.M.8
Quarato, G.9
Gottlieb, R.A.10
Yamaguchi, M.11
Nizet, V.12
Dahl, R.13
Thomas, D.D.14
Tait, S.W.15
Green, D.R.16
Fisher, P.B.17
Matsuzawa, S.18
Reed, J.C.19
-
189
-
-
79952228407
-
Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis
-
Guo J.Y., Chen H.Y., Mathew R., Fan J., Strohecker A.M., Karsli-Uzunbas G., Kamphorst J.J., Chen G., Lemons J.M., Karantza V., Coller H.A., Dipaola R.S., Gelinas C., Rabinowitz J.D., White E. Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis. Genes Dev. 2011, 25:460-470.
-
(2011)
Genes Dev.
, vol.25
, pp. 460-470
-
-
Guo, J.Y.1
Chen, H.Y.2
Mathew, R.3
Fan, J.4
Strohecker, A.M.5
Karsli-Uzunbas, G.6
Kamphorst, J.J.7
Chen, G.8
Lemons, J.M.9
Karantza, V.10
Coller, H.A.11
Dipaola, R.S.12
Gelinas, C.13
Rabinowitz, J.D.14
White, E.15
-
190
-
-
79955643961
-
KRAS-induced actin-interacting protein regulates inositol 1,4,5-trisphosphate-receptor-mediated calcium release
-
Fujimoto T., Machida T., Tsunoda T., Doi K., Ota T., Kuroki M., Shirasawa S. KRAS-induced actin-interacting protein regulates inositol 1,4,5-trisphosphate-receptor-mediated calcium release. Biochem. Biophys. Res. Commun. 2011, 408:214-217.
-
(2011)
Biochem. Biophys. Res. Commun.
, vol.408
, pp. 214-217
-
-
Fujimoto, T.1
Machida, T.2
Tsunoda, T.3
Doi, K.4
Ota, T.5
Kuroki, M.6
Shirasawa, S.7
-
191
-
-
80455173839
-
BAX inhibitor-1 regulates autophagy by controlling the IRE1alpha branch of the unfolded protein response
-
Castillo K., Rojas-Rivera D., Lisbona F., Caballero B., Nassif M., Court F.A., Schuck S., Ibar C., Walter P., Sierralta J., Glavic A., Hetz C. BAX inhibitor-1 regulates autophagy by controlling the IRE1alpha branch of the unfolded protein response. EMBO J. 2011, 30:4465-4478.
-
(2011)
EMBO J.
, vol.30
, pp. 4465-4478
-
-
Castillo, K.1
Rojas-Rivera, D.2
Lisbona, F.3
Caballero, B.4
Nassif, M.5
Court, F.A.6
Schuck, S.7
Ibar, C.8
Walter, P.9
Sierralta, J.10
Glavic, A.11
Hetz, C.12
-
192
-
-
62549129467
-
BAX inhibitor-1 is a negative regulator of the ER stress sensor IRE1alpha
-
Lisbona F., Rojas-Rivera D., Thielen P., Zamorano S., Todd D., Martinon F., Glavic A., Kress C., Lin J.H., Walter P., Reed J.C., Glimcher L.H., Hetz C. BAX inhibitor-1 is a negative regulator of the ER stress sensor IRE1alpha. Mol. Cell 2009, 33:679-691.
-
(2009)
Mol. Cell
, vol.33
, pp. 679-691
-
-
Lisbona, F.1
Rojas-Rivera, D.2
Thielen, P.3
Zamorano, S.4
Todd, D.5
Martinon, F.6
Glavic, A.7
Kress, C.8
Lin, J.H.9
Walter, P.10
Reed, J.C.11
Glimcher, L.H.12
Hetz, C.13
-
193
-
-
0442293930
-
Deregulated expression of KRAP, a novel gene encoding actin-interacting protein, in human colon cancer cells
-
Inokuchi J., Komiya M., Baba I., Naito S., Sasazuki T., Shirasawa S. Deregulated expression of KRAP, a novel gene encoding actin-interacting protein, in human colon cancer cells. J. Hum. Genet. 2004, 49:46-52.
-
(2004)
J. Hum. Genet.
, vol.49
, pp. 46-52
-
-
Inokuchi, J.1
Komiya, M.2
Baba, I.3
Naito, S.4
Sasazuki, T.5
Shirasawa, S.6
-
194
-
-
36448987897
-
Analysis of KRAP expression and localization, and genes regulated by KRAP in a human colon cancer cell line
-
Fujimoto T., Koyanagi M., Baba I., Nakabayashi K., Kato N., Sasazuki T., Shirasawa S. Analysis of KRAP expression and localization, and genes regulated by KRAP in a human colon cancer cell line. J. Hum. Genet. 2007, 52:978-984.
-
(2007)
J. Hum. Genet.
, vol.52
, pp. 978-984
-
-
Fujimoto, T.1
Koyanagi, M.2
Baba, I.3
Nakabayashi, K.4
Kato, N.5
Sasazuki, T.6
Shirasawa, S.7
-
195
-
-
58749114217
-
Altered energy homeostasis and resistance to diet-induced obesity in KRAP-deficient mice
-
Fujimoto T., Miyasaka K., Koyanagi M., Tsunoda T., Baba I., Doi K., Ohta M., Kato N., Sasazuki T., Shirasawa S. Altered energy homeostasis and resistance to diet-induced obesity in KRAP-deficient mice. PLoS One 2009, 4:e4240.
-
(2009)
PLoS One
, vol.4
-
-
Fujimoto, T.1
Miyasaka, K.2
Koyanagi, M.3
Tsunoda, T.4
Baba, I.5
Doi, K.6
Ohta, M.7
Kato, N.8
Sasazuki, T.9
Shirasawa, S.10
-
196
-
-
84872574710
-
Vimentin and the K-Ras-induced actin-binding protein control inositol-(1,4,5)-trisphosphate receptor redistribution during MDCK cell differentiation
-
Dingli F., Parys J.B., Loew D., Saule S., Mery L. Vimentin and the K-Ras-induced actin-binding protein control inositol-(1,4,5)-trisphosphate receptor redistribution during MDCK cell differentiation. J. Cell Sci. 2012, 10.3892/ijmm.2012.1126.
-
(2012)
J. Cell Sci.
-
-
Dingli, F.1
Parys, J.B.2
Loew, D.3
Saule, S.4
Mery, L.5
-
198
-
-
79955657933
-
Determination of the critical region of KRAS-induced actin-interacting protein for the interaction with inositol 1,4,5-trisphosphate receptor
-
Fujimoto T., Machida T., Tsunoda T., Doi K., Ota T., Kuroki M., Shirasawa S. Determination of the critical region of KRAS-induced actin-interacting protein for the interaction with inositol 1,4,5-trisphosphate receptor. Biochem. Biophys. Res. Commun. 2011, 408:282-286.
-
(2011)
Biochem. Biophys. Res. Commun.
, vol.408
, pp. 282-286
-
-
Fujimoto, T.1
Machida, T.2
Tsunoda, T.3
Doi, K.4
Ota, T.5
Kuroki, M.6
Shirasawa, S.7
-
199
-
-
79961196563
-
KRAS-induced actin-interacting protein: a potent target for obesity, diabetes and cancer
-
Fujimoto T., Shirasawa S. KRAS-induced actin-interacting protein: a potent target for obesity, diabetes and cancer. Anticancer Res. 2011, 31:2413-2417.
-
(2011)
Anticancer Res.
, vol.31
, pp. 2413-2417
-
-
Fujimoto, T.1
Shirasawa, S.2
-
200
-
-
80052267874
-
Vimentin in cancer and its potential as a molecular target for cancer therapy
-
Satelli A., Li S. Vimentin in cancer and its potential as a molecular target for cancer therapy. Cell. Mol. Life Sci. 2011, 68:3033-3046.
-
(2011)
Cell. Mol. Life Sci.
, vol.68
, pp. 3033-3046
-
-
Satelli, A.1
Li, S.2
-
201
-
-
0037169341
-
The role of PML in tumor suppression
-
Salomoni P., Pandolfi P.P. The role of PML in tumor suppression. Cell 2002, 108:165-170.
-
(2002)
Cell
, vol.108
, pp. 165-170
-
-
Salomoni, P.1
Pandolfi, P.P.2
-
202
-
-
44849143636
-
New insights into the role of PML in tumour suppression
-
Salomoni P., Ferguson B.J., Wyllie A.H., Rich T. New insights into the role of PML in tumour suppression. Cell Res. 2008, 18:622-640.
-
(2008)
Cell Res.
, vol.18
, pp. 622-640
-
-
Salomoni, P.1
Ferguson, B.J.2
Wyllie, A.H.3
Rich, T.4
-
203
-
-
80051770868
-
The role of PML in the control of apoptotic cell fate: a new key player at ER-mitochondria sites
-
Pinton P., Giorgi C., Pandolfi P.P. The role of PML in the control of apoptotic cell fate: a new key player at ER-mitochondria sites. Cell Death Differ. 2011, 18:1450-1456.
-
(2011)
Cell Death Differ.
, vol.18
, pp. 1450-1456
-
-
Pinton, P.1
Giorgi, C.2
Pandolfi, P.P.3
-
204
-
-
36448975490
-
Structure, dynamics and functions of promyelocytic leukaemia nuclear bodies
-
Bernardi R., Pandolfi P.P. Structure, dynamics and functions of promyelocytic leukaemia nuclear bodies. Nat. Rev. Mol. Cell Biol. 2007, 8:1006-1016.
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 1006-1016
-
-
Bernardi, R.1
Pandolfi, P.P.2
-
205
-
-
54249103056
-
Regulation of apoptosis by PML and the PML-NBs
-
Bernardi R., Papa A., Pandolfi P.P. Regulation of apoptosis by PML and the PML-NBs. Oncogene 2008, 27:6299-6312.
-
(2008)
Oncogene
, vol.27
, pp. 6299-6312
-
-
Bernardi, R.1
Papa, A.2
Pandolfi, P.P.3
-
206
-
-
0031791875
-
PML is essential for multiple apoptotic pathways
-
Wang Z.G., Ruggero D., Ronchetti S., Zhong S., Gaboli M., Rivi R., Pandolfi P.P. PML is essential for multiple apoptotic pathways. Nat. Genet. 1998, 20:266-272.
-
(1998)
Nat. Genet.
, vol.20
, pp. 266-272
-
-
Wang, Z.G.1
Ruggero, D.2
Ronchetti, S.3
Zhong, S.4
Gaboli, M.5
Rivi, R.6
Pandolfi, P.P.7
-
207
-
-
0035910747
-
Role of promyelocytic leukemia (PML) protein in tumor suppression
-
Rego E.M., Wang Z.G., Peruzzi D., He L.Z., Cordon-Cardo C., Pandolfi P.P. Role of promyelocytic leukemia (PML) protein in tumor suppression. J. Exp. Med. 2001, 193:521-529.
-
(2001)
J. Exp. Med.
, vol.193
, pp. 521-529
-
-
Rego, E.M.1
Wang, Z.G.2
Peruzzi, D.3
He, L.Z.4
Cordon-Cardo, C.5
Pandolfi, P.P.6
-
208
-
-
33745316089
-
Identification of a tumour suppressor network opposing nuclear Akt function
-
Trotman L.C., Alimonti A., Scaglioni P.P., Koutcher J.A., Cordon-Cardo C., Pandolfi P.P. Identification of a tumour suppressor network opposing nuclear Akt function. Nature 2006, 441:523-527.
-
(2006)
Nature
, vol.441
, pp. 523-527
-
-
Trotman, L.C.1
Alimonti, A.2
Scaglioni, P.P.3
Koutcher, J.A.4
Cordon-Cardo, C.5
Pandolfi, P.P.6
-
209
-
-
78649425814
-
PML regulates apoptosis at endoplasmic reticulum by modulating calcium release
-
Giorgi C., Ito K., Lin H.K., Santangelo C., Wieckowski M.R., Lebiedzinska M., Bononi A., Bonora M., Duszynski J., Bernardi R., Rizzuto R., Tacchetti C., Pinton P., Pandolfi P.P. PML regulates apoptosis at endoplasmic reticulum by modulating calcium release. Science 2010, 330:1247-1251.
-
(2010)
Science
, vol.330
, pp. 1247-1251
-
-
Giorgi, C.1
Ito, K.2
Lin, H.K.3
Santangelo, C.4
Wieckowski, M.R.5
Lebiedzinska, M.6
Bononi, A.7
Bonora, M.8
Duszynski, J.9
Bernardi, R.10
Rizzuto, R.11
Tacchetti, C.12
Pinton, P.13
Pandolfi, P.P.14
-
210
-
-
0033104513
-
Encoding of Ca2+ signals by differential expression of IP3 receptor subtypes
-
Miyakawa T., Maeda A., Yamazawa T., Hirose K., Kurosaki T., Iino M. Encoding of Ca2+ signals by differential expression of IP3 receptor subtypes. EMBO J. 1999, 18:1303-1308.
-
(1999)
EMBO J.
, vol.18
, pp. 1303-1308
-
-
Miyakawa, T.1
Maeda, A.2
Yamazawa, T.3
Hirose, K.4
Kurosaki, T.5
Iino, M.6
-
211
-
-
84863807029
-
Signaling pathways activated by the B-cell receptor in chronic lymphocytic leukemia
-
Scupoli M.T., Pizzolo G. Signaling pathways activated by the B-cell receptor in chronic lymphocytic leukemia. Expert Rev. Hematol. 2012, 5:341-348.
-
(2012)
Expert Rev. Hematol.
, vol.5
, pp. 341-348
-
-
Scupoli, M.T.1
Pizzolo, G.2
-
212
-
-
84865176364
-
The B-cell receptor signaling pathway as a therapeutic target in CLL
-
Woyach J.A., Johnson A.J., Byrd J.C. The B-cell receptor signaling pathway as a therapeutic target in CLL. Blood 2012, 120:1175-1184.
-
(2012)
Blood
, vol.120
, pp. 1175-1184
-
-
Woyach, J.A.1
Johnson, A.J.2
Byrd, J.C.3
-
213
-
-
68149139456
-
The autophagy effector Beclin 1: a novel BH3-only protein
-
Sinha S., Levine B. The autophagy effector Beclin 1: a novel BH3-only protein. Oncogene 2008, 27(Suppl. 1):S137-S148.
-
(2008)
Oncogene
, vol.27
, Issue.SUPPL. 1
-
-
Sinha, S.1
Levine, B.2
-
214
-
-
80655124407
-
A comprehensive glossary of autophagy-related molecules and processes (2nd edition)
-
Klionsky D.J., Baehrecke E.H., Brumell J.H., Chu C.T., Codogno P., Cuervo A.M., Debnath J., Deretic V., Elazar Z., Eskelinen E.L., Finkbeiner S., Fueyo-Margareto J., Gewirtz D., Jaattela M., Kroemer G., Levine B., Melia T.J., Mizushima N., Rubinsztein D.C., Simonsen A., Thorburn A., Thumm M., Tooze S.A. A comprehensive glossary of autophagy-related molecules and processes (2nd edition). Autophagy 2011, 7:1273-1294.
-
(2011)
Autophagy
, vol.7
, pp. 1273-1294
-
-
Klionsky, D.J.1
Baehrecke, E.H.2
Brumell, J.H.3
Chu, C.T.4
Codogno, P.5
Cuervo, A.M.6
Debnath, J.7
Deretic, V.8
Elazar, Z.9
Eskelinen, E.L.10
Finkbeiner, S.11
Fueyo-Margareto, J.12
Gewirtz, D.13
Jaattela, M.14
Kroemer, G.15
Levine, B.16
Melia, T.J.17
Mizushima, N.18
Rubinsztein, D.C.19
Simonsen, A.20
Thorburn, A.21
Thumm, M.22
Tooze, S.A.23
more..
-
215
-
-
79952628267
-
The Beclin 1 network regulates autophagy and apoptosis
-
Kang R., Zeh H.J., Lotze M.T., Tang D. The Beclin 1 network regulates autophagy and apoptosis. Cell Death Differ. 2011, 18:571-580.
-
(2011)
Cell Death Differ.
, vol.18
, pp. 571-580
-
-
Kang, R.1
Zeh, H.J.2
Lotze, M.T.3
Tang, D.4
-
216
-
-
61849102389
-
DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-XL and induction of autophagy
-
Zalckvar E., Berissi H., Mizrachy L., Idelchuk Y., Koren I., Eisenstein M., Sabanay H., Pinkas-Kramarski R., Kimchi A. DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-XL and induction of autophagy. EMBO Rep. 2009, 10:285-292.
-
(2009)
EMBO Rep.
, vol.10
, pp. 285-292
-
-
Zalckvar, E.1
Berissi, H.2
Mizrachy, L.3
Idelchuk, Y.4
Koren, I.5
Eisenstein, M.6
Sabanay, H.7
Pinkas-Kramarski, R.8
Kimchi, A.9
-
217
-
-
67650270918
-
Phosphorylation of Beclin 1 by DAP-kinase promotes autophagy by weakening its interactions with Bcl-2 and Bcl-XL
-
Zalckvar E., Berissi H., Eisenstein M., Kimchi A. Phosphorylation of Beclin 1 by DAP-kinase promotes autophagy by weakening its interactions with Bcl-2 and Bcl-XL. Autophagy 2009, 5:720-722.
-
(2009)
Autophagy
, vol.5
, pp. 720-722
-
-
Zalckvar, E.1
Berissi, H.2
Eisenstein, M.3
Kimchi, A.4
-
218
-
-
77951217470
-
Lethal weapons: DAP-kinase, autophagy and cell death: DAP-kinase regulates autophagy
-
Bialik S., Kimchi A. Lethal weapons: DAP-kinase, autophagy and cell death: DAP-kinase regulates autophagy. Curr. Opin. Cell Biol. 2010, 22:199-205.
-
(2010)
Curr. Opin. Cell Biol.
, vol.22
, pp. 199-205
-
-
Bialik, S.1
Kimchi, A.2
-
219
-
-
44949237240
-
JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy
-
Wei Y., Pattingre S., Sinha S., Bassik M., Levine B. JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy. Mol. Cell 2008, 30:678-688.
-
(2008)
Mol. Cell
, vol.30
, pp. 678-688
-
-
Wei, Y.1
Pattingre, S.2
Sinha, S.3
Bassik, M.4
Levine, B.5
-
220
-
-
59149090850
-
Role of JNK1-dependent Bcl-2 phosphorylation in ceramide-induced macroautophagy
-
Pattingre S., Bauvy C., Carpentier S., Levade T., Levine B., Codogno P. Role of JNK1-dependent Bcl-2 phosphorylation in ceramide-induced macroautophagy. J. Biol. Chem. 2009, 284:2719-2728.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 2719-2728
-
-
Pattingre, S.1
Bauvy, C.2
Carpentier, S.3
Levade, T.4
Levine, B.5
Codogno, P.6
-
221
-
-
75149146637
-
Evidence for the interplay between JNK and p53-DRAM signalling pathways in the regulation of autophagy
-
Lorin S., Pierron G., Ryan K.M., Codogno P., Djavaheri-Mergny M. Evidence for the interplay between JNK and p53-DRAM signalling pathways in the regulation of autophagy. Autophagy 2010, 6:153-154.
-
(2010)
Autophagy
, vol.6
, pp. 153-154
-
-
Lorin, S.1
Pierron, G.2
Ryan, K.M.3
Codogno, P.4
Djavaheri-Mergny, M.5
-
222
-
-
84869147050
-
Akt-mediated regulation of autophagy and tumorigenesis through beclin 1 phosphorylation
-
Wang R.C., Wei Y., An Z., Zou Z., Xiao G., Bhagat G., White M., Reichelt J., Levine B. Akt-mediated regulation of autophagy and tumorigenesis through beclin 1 phosphorylation. Science 2012, 338:956-959.
-
(2012)
Science
, vol.338
, pp. 956-959
-
-
Wang, R.C.1
Wei, Y.2
An, Z.3
Zou, Z.4
Xiao, G.5
Bhagat, G.6
White, M.7
Reichelt, J.8
Levine, B.9
-
223
-
-
84869124927
-
Promoting tumorigenesis by suppressing autophagy
-
Koren I., Kimchi A. Promoting tumorigenesis by suppressing autophagy. Science 2012, 338:889-890.
-
(2012)
Science
, vol.338
, pp. 889-890
-
-
Koren, I.1
Kimchi, A.2
-
225
-
-
85117876522
-
Regulation of the autophagic Bcl-2/Beclin 1 interaction
-
Decuypere J.P., Parys J.B., Bultynck G. Regulation of the autophagic Bcl-2/Beclin 1 interaction. Cells 2012, 1:284-312.
-
(2012)
Cells
, vol.1
, pp. 284-312
-
-
Decuypere, J.P.1
Parys, J.B.2
Bultynck, G.3
-
226
-
-
0000906170
-
Induction of autophagy and inhibition of tumorigenesis by beclin 1
-
Liang X.H., Jackson S., Seaman M., Brown K., Kempkes B., Hibshoosh H., Levine B. Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature 1999, 402:672-676.
-
(1999)
Nature
, vol.402
, pp. 672-676
-
-
Liang, X.H.1
Jackson, S.2
Seaman, M.3
Brown, K.4
Kempkes, B.5
Hibshoosh, H.6
Levine, B.7
-
227
-
-
2442482810
-
Autophagy as a cell death and tumor suppressor mechanism
-
Gozuacik D., Kimchi A. Autophagy as a cell death and tumor suppressor mechanism. Oncogene 2004, 23:2891-2906.
-
(2004)
Oncogene
, vol.23
, pp. 2891-2906
-
-
Gozuacik, D.1
Kimchi, A.2
-
228
-
-
9144240441
-
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene
-
Qu X., Yu J., Bhagat G., Furuya N., Hibshoosh H., Troxel A., Rosen J., Eskelinen E.L., Mizushima N., Ohsumi Y., Cattoretti G., Levine B. Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene. J. Clin. Invest. 2003, 112:1809-1820.
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 1809-1820
-
-
Qu, X.1
Yu, J.2
Bhagat, G.3
Furuya, N.4
Hibshoosh, H.5
Troxel, A.6
Rosen, J.7
Eskelinen, E.L.8
Mizushima, N.9
Ohsumi, Y.10
Cattoretti, G.11
Levine, B.12
-
229
-
-
0345166111
-
Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
-
Yue Z., Jin S., Yang C., Levine A.J., Heintz N. Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor. Proc. Natl. Acad. Sci. U.S.A. 2003, 100:15077-15082.
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 15077-15082
-
-
Yue, Z.1
Jin, S.2
Yang, C.3
Levine, A.J.4
Heintz, N.5
-
230
-
-
84861526009
-
Deconvoluting the context-dependent role for autophagy in cancer
-
White E. Deconvoluting the context-dependent role for autophagy in cancer. Nat. Rev. Cancer 2012, 12:401-410.
-
(2012)
Nat. Rev. Cancer
, vol.12
, pp. 401-410
-
-
White, E.1
-
231
-
-
79551634458
-
Autophagy in tumorigenesis and energy metabolism: friend by day, foe by night
-
Mathew R., White E. Autophagy in tumorigenesis and energy metabolism: friend by day, foe by night. Curr. Opin. Genet. Dev. 2011, 21:113-119.
-
(2011)
Curr. Opin. Genet. Dev.
, vol.21
, pp. 113-119
-
-
Mathew, R.1
White, E.2
-
232
-
-
0344142468
-
Cloning and genomic organization of beclin 1, a candidate tumor suppressor gene on chromosome 17q21
-
Aita V.M., Liang X.H., Murty V.V., Pincus D.L., Yu W., Cayanis E., Kalachikov S., Gilliam T.C., Levine B. Cloning and genomic organization of beclin 1, a candidate tumor suppressor gene on chromosome 17q21. Genomics 1999, 59:59-65.
-
(1999)
Genomics
, vol.59
, pp. 59-65
-
-
Aita, V.M.1
Liang, X.H.2
Murty, V.V.3
Pincus, D.L.4
Yu, W.5
Cayanis, E.6
Kalachikov, S.7
Gilliam, T.C.8
Levine, B.9
-
233
-
-
69349087479
-
Anti- and pro-tumor functions of autophagy
-
Morselli E., Galluzzi L., Kepp O., Vicencio J.M., Criollo A., Maiuri M.C., Kroemer G. Anti- and pro-tumor functions of autophagy. Biochim. Biophys. Acta 2009, 1793:1524-1532.
-
(2009)
Biochim. Biophys. Acta
, vol.1793
, pp. 1524-1532
-
-
Morselli, E.1
Galluzzi, L.2
Kepp, O.3
Vicencio, J.M.4
Criollo, A.5
Maiuri, M.C.6
Kroemer, G.7
-
234
-
-
67549135655
-
The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1
-
Vicencio J.M., Ortiz C., Criollo A., Jones A.W., Kepp O., Galluzzi L., Joza N., Vitale I., Morselli E., Tailler M., Castedo M., Maiuri M.C., Molgo J., Szabadkai G., Lavandero S., Kroemer G. The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1. Cell Death Differ. 2009, 16:1006-1017.
-
(2009)
Cell Death Differ.
, vol.16
, pp. 1006-1017
-
-
Vicencio, J.M.1
Ortiz, C.2
Criollo, A.3
Jones, A.W.4
Kepp, O.5
Galluzzi, L.6
Joza, N.7
Vitale, I.8
Morselli, E.9
Tailler, M.10
Castedo, M.11
Maiuri, M.C.12
Molgo, J.13
Szabadkai, G.14
Lavandero, S.15
Kroemer, G.16
-
235
-
-
82855169506
-
IP 3 receptor-mediated Ca (2+) signaling and autophagy induction are interrelated
-
Decuypere J.P., Welkenhuyzen K., Luyten T., Ponsaerts R., Dewaele M., Molgo J., Agostinis P., Missiaen L., De Smedt H., Parys J.B., Bultynck G. IP 3 receptor-mediated Ca (2+) signaling and autophagy induction are interrelated. Autophagy 2011, 7.
-
(2011)
Autophagy
, vol.7
-
-
Decuypere, J.P.1
Welkenhuyzen, K.2
Luyten, T.3
Ponsaerts, R.4
Dewaele, M.5
Molgo, J.6
Agostinis, P.7
Missiaen, L.8
De Smedt, H.9
Parys, J.B.10
Bultynck, G.11
-
237
-
-
84862779963
-
3 receptors, mitochondria, and Ca signaling: implications for aging
-
3 receptors, mitochondria, and Ca signaling: implications for aging. J. Aging Res. 2011, 2011:920178.
-
(2011)
J. Aging Res.
, vol.2011
, pp. 920178
-
-
Decuypere, J.P.1
Monaco, G.2
Missiaen, L.3
De Smedt, H.4
Parys, J.B.5
Bultynck, G.6
|