-
1
-
-
33847328289
-
The Bcl-2 apoptotic switch in cancer development and therapy
-
DOI 10.1038/sj.onc.1210220, PII 1210220
-
Adams JM, Cory S. The Bcl-2 apoptotic switch in cancer development and therapy. Oncogene. 2007;26(9):1324-1337. (Pubitemid 46328466)
-
(2007)
Oncogene
, vol.26
, Issue.9
, pp. 1324-1337
-
-
Adams, J.M.1
Cory, S.2
-
2
-
-
54949132875
-
Bcl-2 family proteins and cancer
-
Yip KW, Reed JC. Bcl-2 family proteins and cancer. Oncogene. 2008;27(50):6398-6406.
-
(2008)
Oncogene
, vol.27
, Issue.50
, pp. 6398-6406
-
-
Yip, K.W.1
Reed, J.C.2
-
3
-
-
0021679848
-
Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation
-
Tsujimoto Y, Finger LR, Yunis J, Nowell PC, Croce CM. Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation. Science. 1984;226(4678):1097-1099. (Pubitemid 15217831)
-
(1984)
Science
, vol.226
, Issue.4678
, pp. 1097-1099
-
-
Tsujimoto, Y.1
Finger, L.R.2
Yunis, J.3
-
4
-
-
25444520537
-
MiR-15 and miR-16 induce apoptosis by targeting BCL2
-
DOI 10.1073/pnas.0506654102
-
Cimmino A, Calin GA, Fabbri M, et al. miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc Natl Acad Sci U S A. 2005;102(39):13944-13949. (Pubitemid 41377683)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.39
, pp. 13944-13949
-
-
Cimmino, A.1
Calin, G.A.2
Fabbri, M.3
Iorio, M.V.4
Ferracin, M.5
Shimizu, M.6
Wojcik, S.E.7
Aqeilan, R.I.8
Zupo, S.9
Dono, M.10
Rassenti, L.11
Alder, H.12
Volinia, S.13
Liu, C.-G.14
Kipps, T.J.15
Negrini, M.16
Croce, C.M.17
-
5
-
-
74049097902
-
Chronic lymphocytic leukemia: Interplay between noncoding RNAs and protein-coding genes
-
Calin GA, Croce C. Chronic lymphocytic leukemia: interplay between noncoding RNAs and protein-coding genes. Blood. 2009;114(23):4761-4770.
-
(2009)
Blood
, vol.114
, Issue.23
, pp. 4761-4770
-
-
Calin, G.A.1
Croce, C.2
-
6
-
-
70349562920
-
Molecular and cellular mechanisms of CLL: Novel therapeutic approaches
-
Pleyer L, Egle A, Hartmann TN, Greil R. Molecular and cellular mechanisms of CLL: novel therapeutic approaches. Nat Rev Clin Oncol. 2009;6(7):405-418.
-
(2009)
Nat Rev Clin Oncol
, vol.6
, Issue.7
, pp. 405-418
-
-
Pleyer, L.1
Egle, A.2
Hartmann, T.N.3
Greil, R.4
-
7
-
-
37549048249
-
The Bcl-2 protein family: Opposing activities that mediate cell death
-
Youle RJ, Strasser A. The Bcl-2 protein family: opposing activities that mediate cell death. Nat Rev Mol Cell Biol. 2008;9(1):47-59.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, Issue.1
, pp. 47-59
-
-
Youle, R.J.1
Strasser, A.2
-
8
-
-
75949105922
-
The BCL-2 family reunion
-
Chipuk JE, Moldoveanu T, Llambi F, Parsons MJ, Green DR. The BCL-2 family reunion. Mol Cell. 2010;37(3):299-310.
-
(2010)
Mol Cell
, vol.37
, Issue.3
, pp. 299-310
-
-
Chipuk, J.E.1
Moldoveanu, T.2
Llambi, F.3
Parsons, M.J.4
Green, D.R.5
-
9
-
-
38549145044
-
Diagnosing and exploiting cancer's addiction to blocks in apoptosis
-
DOI 10.1038/nrc2297, PII NRC2297
-
Letai AG. Diagnosing and exploiting cancer's addiction to blocks in apoptosis. Nat Rev Cancer. 2008;8(2):121-132. (Pubitemid 351161322)
-
(2008)
Nature Reviews Cancer
, vol.8
, Issue.2
, pp. 121-132
-
-
Letai, A.G.1
-
10
-
-
68749112763
-
Small-molecule Bcl-2 antagonists as targeted therapy in oncology
-
Warr MR, Shore GC. Small-molecule Bcl-2 antagonists as targeted therapy in oncology. Curr Oncol. 2008;15(6):256-261.
-
(2008)
Curr Oncol
, vol.15
, Issue.6
, pp. 256-261
-
-
Warr, M.R.1
Shore, G.C.2
-
11
-
-
60849086456
-
Bcl-2 inhibitors: Small molecules with a big impact on cancer therapy
-
Vogler M, Dinsdale D, Dyer MJ, Cohen GM. Bcl-2 inhibitors: small molecules with a big impact on cancer therapy. Cell Death Differ. 2009;16(3):360-367.
-
(2009)
Cell Death Differ
, vol.16
, Issue.3
, pp. 360-367
-
-
Vogler, M.1
Dinsdale, D.2
Dyer, M.J.3
Cohen, G.M.4
-
12
-
-
33745958168
-
2+ homeostasis in the endoplasmic reticulum
-
DOI 10.1038/sj.cdd.4401960, PII 4401960
-
Pinton P, Rizzuto R. Bcl-2 and Ca2+ homeostasis in the endoplasmic reticulum. Cell Death Differ. 2006;13(8):1409-1418. (Pubitemid 44057477)
-
(2006)
Cell Death and Differentiation
, vol.13
, Issue.8
, pp. 1409-1418
-
-
Pinton, P.1
Rizzuto, R.2
-
13
-
-
54949135707
-
The endoplasmic reticulum in apoptosis and autophagy: Role of the Bcl-2 protein family
-
Heath-Engel HM, Chang NC, Shore GC. The endoplasmic reticulum in apoptosis and autophagy: role of the Bcl-2 protein family. Oncogene. 2008;27(50):6419-6433.
-
(2008)
Oncogene
, vol.27
, Issue.50
, pp. 6419-6433
-
-
Heath-Engel, H.M.1
Chang, N.C.2
Shore, G.C.3
-
14
-
-
42549144606
-
Bcl-2 protein family members: Versatile regulators of calcium signaling in cell survival and apoptosis
-
DOI 10.1146/annurev.physiol.70.021507.105852
-
Rong Y, Distelhorst CW. Bcl-2 protein family: Versatile regulators of calcium signaling in cell survival and apoptosis. Annu Rev Physiol. 2008;70:73-91. (Pubitemid 351738172)
-
(2008)
Annual Review of Physiology
, vol.70
, pp. 73-91
-
-
Rong, Y.1
Distelhorst, C.W.2
-
15
-
-
24644471966
-
The inositol 1,4,5-trisphosphate receptors
-
Bezprozvanny I. The inositol 1,4,5-trisphosphate receptors. Cell Calcium. 2005;38(3-4):261-272.
-
(2005)
Cell Calcium
, vol.38
, Issue.3-4
, pp. 261-272
-
-
Bezprozvanny, I.1
-
16
-
-
34248584090
-
2+ release channels
-
DOI 10.1152/physrev.00035.2006
-
Foskett JK, White C, Cheung KH, Mak DO. Inositol trisphosphate receptor Ca2+ release channels. Physiol Rev. 2007;87(2):593-658. (Pubitemid 47084681)
-
(2007)
Physiological Reviews
, vol.87
, Issue.2
, pp. 593-658
-
-
Foskett, J.K.1
White, C.2
Cheung, K.-H.3
Mak, D.-O.D.4
-
17
-
-
0038125598
-
Calcium signalling: Dynamics, homeostasis and remodelling
-
DOI 10.1038/nrm1155
-
Berridge MJ, Bootman MD, Roderick HL. Calcium signaling: dynamics, homeostasis and remodelling. Nat Rev Mol Cell Biol. 2003;4(7):517-529. (Pubitemid 36773404)
-
(2003)
Nature Reviews Molecular Cell Biology
, vol.4
, Issue.7
, pp. 517-529
-
-
Berridge, M.J.1
Bootman, M.D.2
Roderick, H.L.3
-
18
-
-
0035064074
-
Calcium signaling mechanisms in T lymphocytes
-
DOI 10.1146/annurev.immunol.19.1.497
-
Lewis RS. Calcium signaling mechanisms in T lymphocytes. Annu Rev Immunol. 2001;19:497-521. (Pubitemid 32368044)
-
(2001)
Annual Review of Immunology
, vol.19
, pp. 497-521
-
-
Lewis, R.S.1
-
20
-
-
34247480926
-
2+ release and beyond
-
DOI 10.1007/s10495-007-0719-7, Special Issue on Mitochondria in Apoptosis
-
Joseph SK, Hajnoczky G. IP3 receptors in cell survival and apoptosis: Ca2+ release and beyond. Apoptosis. 2007;12(5):951-968. (Pubitemid 46653288)
-
(2007)
Apoptosis
, vol.12
, Issue.5
, pp. 951-968
-
-
Joseph, S.K.1
Hajnoczky, G.2
-
21
-
-
42549164808
-
Ca2+ signalling checkpoints in cancer: Remodelling Ca2+ for cancer cell proliferation and survival
-
Roderick HL, Cook SJ. Ca2+ signalling checkpoints in cancer: remodelling Ca2+ for cancer cell proliferation and survival. Nat Rev Cancer. 2008;8(5):361-365.
-
(2008)
Nat Rev Cancer
, vol.8
, Issue.5
, pp. 361-365
-
-
Roderick, H.L.1
Cook, S.J.2
-
22
-
-
29944435173
-
2+ signals according to the strength of T cell receptor activation
-
DOI 10.1083/jcb.200506189
-
Zhong F, Davis MC, McColl KS, Distelhorst CW. Bcl-2 differentially regulates Ca2+ signals according to the strength of T cell receptor activation. J Cell Biol. 2006;172(1):127-137. (Pubitemid 43042635)
-
(2006)
Journal of Cell Biology
, vol.172
, Issue.1
, pp. 127-137
-
-
Zhong, F.1
Davis, M.C.2
McColl, K.S.3
Distelhorst, C.W.4
-
23
-
-
10644234677
-
2+ analyzed with an improved genetically encoded fluorescent sensor
-
DOI 10.1073/pnas.0408030101
-
Palmer AE, Jin C, Reed JC, Tsien RY. Bcl-2 - mediated alterations in endoplasmic reticulum Ca2+ analyzed with an improved genetically encoded fluorescent sensor. Proc Natl Acad Sci U SA. 2004;101(50):17404-17409. (Pubitemid 39657417)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.50
, pp. 17404-17409
-
-
Palmer, A.E.1
Jin, C.2
Reed, J.C.3
Tsien, R.Y.4
-
24
-
-
27144487808
-
3R
-
DOI 10.1038/ncb1302, PII N1302
-
White C, Li C, Yang J, et al. The endoplasmic reticulum gateway to apoptosis by Bcl-Xl modulation of the InsP3R. Nat Cell Biol. 2005;7(10):1021-1028. (Pubitemid 41486277)
-
(2005)
Nature Cell Biology
, vol.7
, Issue.10
, pp. 1021-1028
-
-
White, C.1
Li, C.2
Yang, J.3
Petrenko, N.B.4
Madesh, M.5
Thompson, C.B.6
Foskett, J.K.7
-
25
-
-
34547617018
-
Apoptosis regulation by Bcl-XL modulation of mammalian inositol 1,4,5-trisphosphate receptor channel isoform gating
-
Li C, Wang X, Vais H, Thompson CB, Foskett JK, White C. Apoptosis regulation by Bcl-XL modulation of mammalian inositol 1,4,5-trisphosphate receptor channel isoform gating. Proc Natl Acad Sci U S A. 2007;104(30):12565- 12570.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, Issue.30
, pp. 12565-12570
-
-
Li, C.1
Wang, X.2
Vais, H.3
Thompson, C.B.4
Foskett, J.K.5
White, C.6
-
26
-
-
77951562760
-
Apoptosis protection by Mcl-1 and Bcl-2 modulation of inositol 1,4,5-trisphosphate receptor-dpendent Ca2+ signaling
-
Eckenrode EF, Yang J, Velmurugan GV, Foskett JK, White C. Apoptosis protection by Mcl-1 and Bcl-2 modulation of inositol 1,4,5-trisphosphate receptor-dpendent Ca2+ signaling. J Biol Chem. 2010;285(18):13678-13684.
-
(2010)
J Biol Chem
, vol.285
, Issue.18
, pp. 13678-13684
-
-
Eckenrode, E.F.1
Yang, J.2
Velmurugan, G.V.3
Foskett, J.K.4
White, C.5
-
27
-
-
77955041880
-
Essential regulation of cell bioenergetics by constitutive InsP3 receptor Ca2+ transfer to mitochondria
-
Cárdenas C, Miller RA, Simth I, et al. Essential regulation of cell bioenergetics by constitutive InsP3 receptor Ca2+ transfer to mitochondria. Cell. 2010;142(2):270-283.
-
(2010)
Cell
, vol.142
, Issue.2
, pp. 270-283
-
-
Cárdenas, C.1
Miller, R.A.2
Simth, I.3
-
28
-
-
3342984659
-
Bcl-2 functionally interacts with inositol 1,4,5-trisphosphate receptors to regulate calcium release from the ER
-
Chen R, Valencia I, Zhong F, et al. Bcl-2 functionally interacts with inositol 1,4,5-trisphosphate receptors to regulate calcium release from the ER. J Cell Biol. 2004;166(2):193-203.
-
(2004)
J Cell Biol
, vol.166
, Issue.2
, pp. 193-203
-
-
Chen, R.1
Valencia, I.2
Zhong, F.3
-
29
-
-
11844284861
-
Proapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulum
-
DOI 10.1073/pnas.0408352102
-
Oakes SA, Scorrano L, Opferman JT, et al. Proapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulum. Proc Natl Acad Sci U SA. 2005;102(1):105-110. (Pubitemid 40094436)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.1
, pp. 105-110
-
-
Oakes, S.A.1
Scorrano, L.2
Opferman, J.T.3
Bassik, M.C.4
Nishino, M.5
Pozzan, T.6
Korsmeyer, S.J.7
-
30
-
-
33645756318
-
Bcl-2 overexpression prevents calcium overload and subsequent apoptosis in dystrophic myotubes
-
Basset O, Boittin F-X, Cognard C, Constantin B, Ruegg UT. Bcl-2 overexpression prevents calcium overload and subsequent apoptosis in dystrophic myotubes. Biochem J. 2006;395(2):267-276.
-
(2006)
Biochem J
, vol.395
, Issue.2
, pp. 267-276
-
-
Basset, O.1
Boittin, F.-X.2
Cognard, C.3
Constantin, B.4
Ruegg, U.T.5
-
31
-
-
33846520546
-
Suppression of IP3-mediated calcium release and apoptosis by Bcl-2 involves the participation of protein phosphatase 1
-
DOI 10.1007/s11010-006-9285-5
-
Xu L, Kong D, Zhu L, Zhu W, Andrews DW, Kuo TH. Suppression of IP3-mediated calcium release and apoptosis by Bcl-2 involves the participation of protein phosphatase 1. Mol Cell Biochem. 2007;295(1-2):153-165. (Pubitemid 46157998)
-
(2007)
Molecular and Cellular Biochemistry
, vol.295
, Issue.1-2
, pp. 153-165
-
-
Xu, L.1
Kong, D.2
Zhu, L.3
Zhu, W.4
Andrews, D.W.5
Kuo, T.H.6
-
32
-
-
47349099011
-
Bcl-2 suppresses Ca2+ release through inositol 1,4,5-trisphosphate receptors and inhibits Ca2+ uptake by mitochondria without affecting ER calcium store content
-
Hanson CJ, Bootman MD, Distelhorst CW, Wojcikiewicz RJ, Roderick HL. Bcl-2 suppresses Ca2+ release through inositol 1,4,5-trisphosphate receptors and inhibits Ca2+ uptake by mitochondria without affecting ER calcium store content. Cell Calcium. 2008;44(3):324-338.
-
(2008)
Cell Calcium
, vol.44
, Issue.3
, pp. 324-338
-
-
Hanson, C.J.1
Bootman, M.D.2
Distelhorst, C.W.3
Wojcikiewicz, R.J.4
Roderick, H.L.5
-
33
-
-
47349089719
-
Targeting Bcl-2-IP3 Receptor Interaction to Reverse Bcl-2's Inhibition of Apoptotic Calcium Signals
-
DOI 10.1016/j.molcel.2008.06.014, PII S1097276508004322
-
Rong Y, Aromolaran AS, Bultynck G, et al. Targeting Bcl-2 - IP3 receptor interaction to reverse Bcl-2's inhibition of apoptotic calcium signals. Mol Cell. 2008;31(2):255-265. (Pubitemid 352001398)
-
(2008)
Molecular Cell
, vol.31
, Issue.2
, pp. 255-265
-
-
Rong, Y.-P.1
Aromolaran, A.S.2
Bultynck, G.3
Zhong, F.4
Li, X.5
McColl, K.6
Matsuyama, S.7
Herlitze, S.8
Roderick, H.L.9
Bootman, M.D.10
Mignery, G.A.11
Parys, J.B.12
De Smedt, H.13
Distelhorst, C.W.14
-
34
-
-
70149105706
-
The BH4 domain of Bcl-2 inhibits ER calcium release and apoptosis by binding the regulatory and coupling domain of the IP3 receptor
-
Rong Y, Bultynck G, Aromolaran AS, et al. The BH4 domain of Bcl-2 inhibits ER calcium release and apoptosis by binding the regulatory and coupling domain of the IP3 receptor. Proc Natl Acad Sci U S A. 2009;106(34):14397-14402.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.34
, pp. 14397-14402
-
-
Rong, Y.1
Bultynck, G.2
Aromolaran, A.S.3
-
35
-
-
33646886822
-
Up-regulation of inositol 1,4,5-trisphosphate receptor type 1 is responsible for a decreased endoplasmic-reticulum Ca2+ content in presenilin double knockout cells
-
Kasri NN, Kocks SL, Verbert L, et al. Up-regulation of inositol 1,4,5-trisphosphate receptor type 1 is responsible for a decreased endoplasmic-reticulum Ca2+ content in presenilin double knockout cells. Cell Calcium. 2006;40(1):41-51.
-
(2006)
Cell Calcium
, vol.40
, Issue.1
, pp. 41-51
-
-
Kasri, N.N.1
Kocks, S.L.2
Verbert, L.3
-
36
-
-
2342595835
-
Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis
-
DOI 10.1038/nm996
-
Wadia JS, Stan RV, Dowdy SF. Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis. Nat Med. 2004;10(3):310-315. (Pubitemid 38667624)
-
(2004)
Nature Medicine
, vol.10
, Issue.3
, pp. 310-315
-
-
Wadia, J.S.1
Stan, R.V.2
Dowdy, S.F.3
-
37
-
-
33947686680
-
Endocytosis targets exogenous material selectively to cathepsin S in live human dendritic cells, while cell-penetrating peptides mediate nonselective transport to cysteine cathepsins
-
DOI 10.1189/jlb.1006600
-
Reich M, van Swieten PF, Sommandas V, et al. Endocytosis targets exogenous material selectively to cathepsin S in live human dendritic cells, while cell penetrating peptides mediate nonselective transport to cystein cathepsins. J Leukoc Biol. 2007;81(4):990-1001. (Pubitemid 46495648)
-
(2007)
Journal of Leukocyte Biology
, vol.81
, Issue.4
, pp. 990-1001
-
-
Reich, M.1
Van Swieten, P.F.2
Sommandas, V.3
Kraus, M.4
Fischer, R.5
Weber, E.6
Kalbacher, H.7
Overkleeft, H.S.8
Driessen, C.9
-
38
-
-
84871967410
-
SVM-based prediction of caspase substrate cleavage sites
-
Wee LJ, Tan TW, Ranganathan S. SVM-based prediction of caspase substrate cleavage sites. BMC Bioinformatics. 2006;7(suppl 5):S14.
-
(2006)
BMC Bioinformatics
, vol.7
, Issue.SUPPL. 5
-
-
Wee, L.J.1
Tan, T.W.2
Ranganathan, S.3
-
39
-
-
0032079746
-
Expression of apoptosis-regulating proteins in chronic lymphocytic leukemia: Correlations with in vitro and in vivo chemoresponses
-
Kitada S, Andersen J, Akar S, et al. Expression of apoptosis-regulating proteins in chronic lymphocytic leukemia: correlations with in vitro and in vivo chemoresponses. Blood. 1998;91(9):3379-3389. (Pubitemid 28193890)
-
(1998)
Blood
, vol.91
, Issue.9
, pp. 3379-3389
-
-
Kitada, S.1
Andersen, J.2
Akar, S.3
Zapata, J.M.4
Takayama, S.5
Krajewski, S.6
Wang, H.-G.7
Zhang, X.8
Bullrich, F.9
Croce, C.M.10
Rai, K.11
Hines, J.12
Reed, J.C.13
-
40
-
-
0032511112
-
2+ responses
-
DOI 10.1126/science.280.5370.1763
-
Rizzuto R, Pinton P, Carrington W, et al. Close contacts with the endoplasmic reticulum as determinants of mitochondrial Ca2+ responses. Science. 1998;280(5370):1763-1766. (Pubitemid 28283502)
-
(1998)
Science
, vol.280
, Issue.5370
, pp. 1763-1766
-
-
Rizzuto, R.1
Pinton, P.2
Carrington, W.3
Fay, F.S.4
Fogarty, K.E.5
Lifshitz, L.M.6
Tuft, R.A.7
Pozzan, T.8
-
41
-
-
0033570890
-
Apoptosis driven by IP(3)-linked mitochondrial calcium signals
-
Szalai G, Krishnamurthy R, Hajnoczky G. Apoptosis driven by IP(3)-linked mitochondrial calcium signals. EMBO J. 1999;18(22):6349-6361.
-
(1999)
EMBO J
, vol.18
, Issue.22
, pp. 6349-6361
-
-
Szalai, G.1
Krishnamurthy, R.2
Hajnoczky, G.3
-
42
-
-
0035421320
-
Propagation of the apoptotic signal by mitochondrial waves
-
DOI 10.1093/emboj/20.15.4107
-
Pacher P, Hajnoczky G. Propagation of the apoptotic signal by mitochondrial waves. EMBO J. 2001;20(15):4107-4121. (Pubitemid 32751827)
-
(2001)
EMBO Journal
, vol.20
, Issue.15
, pp. 4107-4121
-
-
Pacher, P.1
Hajnoczky, G.2
-
43
-
-
33749022800
-
Structural and functional features and significance of the physical linkage between ER and mitochondria
-
DOI 10.1083/jcb.200604016
-
Csordás G, Renken C, Varnai P, et al. Structural and functional features and significance of the physical linkage between ER and mitochondria. J Cell Biol. 2006;174(7):915-921. (Pubitemid 44455180)
-
(2006)
Journal of Cell Biology
, vol.174
, Issue.7
, pp. 915-921
-
-
Csordas, G.1
Renken, C.2
Varnai, P.3
Walter, L.4
Weaver, D.5
Buttle, K.F.6
Balla, T.7
Mannella, C.A.8
Hajnoczky, G.9
-
44
-
-
34250725402
-
2+ as a key regulator of cell life and death
-
DOI 10.1038/sj.cdd.4402147, PII 4402147
-
Giacomello M, Drago I, Pizzo P, Pozzan T. Mitochondrial Ca2+ as a key regulator of cell life and death. Cell Death Differ. 2007;14(7):1267-1274. (Pubitemid 46965258)
-
(2007)
Cell Death and Differentiation
, vol.14
, Issue.7
, pp. 1267-1274
-
-
Giacomello, M.1
Drago, I.2
Pizzo, P.3
Pozzan, T.4
-
45
-
-
33644847375
-
Microdomains of intracellular Ca2+: Molecular determinants and functional consequences
-
Rizzuto R, Pozzan T. Microdomains of intracellular Ca2+: Molecular determinants and functional consequences. Physiol Rev. 2006;86(1):369-408.
-
(2006)
Physiol Rev
, vol.86
, Issue.1
, pp. 369-408
-
-
Rizzuto, R.1
Pozzan, T.2
-
46
-
-
20144385604
-
Chronic lymphocytic leukemia B cells contain anomalous Lyn tyrosine kinase, a putative contribution to defective apoptosis
-
DOI 10.1172/JCI200522094
-
Contri A, Brunati AM, Trentin L, et al. Chronic lymphocytic leukemia B cells contain anomalous Lyn tyrosine kinase, a putative contribution to defective apoptosis. J Clin Invest. 2005;115(2):369-378. (Pubitemid 40385478)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.2
, pp. 369-378
-
-
Contri, A.1
Brunati, A.M.2
Trentin, L.3
Cabrelle, A.4
Miorin, M.5
Cesaro, L.6
Pinna, L.A.7
Zambello, R.8
Semenzato, G.9
Donella-Deana, A.10
-
47
-
-
20444389401
-
Sustained signaling through the B-cell receptor induces Mcl-1 and promotes survival of chronic lymphocytic leukemia B cells
-
DOI 10.1182/blood-2004-07-2669
-
Petlickovski A, Laurenti L, Li X, et al. Sustained signaling through the B-cell receptor induces Mcl-1 and promotes survival of chronic lymphocytic leukemia B cells. Blood. 2005;105(12):4820-4827. (Pubitemid 40807309)
-
(2005)
Blood
, vol.105
, Issue.12
, pp. 4820-4827
-
-
Petlickovski, A.1
Laurenti, L.2
Li, X.3
Marietti, S.4
Chiusolo, P.5
Sica, S.6
Leone, G.7
Efremov, D.G.8
-
48
-
-
34848896885
-
B cell activator PAX5 promotes lymphomagenesis through stimulation of B cell receptor signaling
-
DOI 10.1172/JCI30842
-
Cozma D, Yu D, Hodawadekar S, et al. B cell activator PAX5 promotes lymphomagenesis through stimulation of B-cell receptor signaling. J Clin Invest. 2007;117(9):2602-2610. (Pubitemid 47494361)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.9
, pp. 2602-2610
-
-
Cozma, D.1
Yu, D.2
Hodawadekar, S.3
Azvolinsky, A.4
Grande, S.5
Tobias, J.W.6
Metzgar, M.H.7
Paterson, J.8
Erikson, J.9
Marafioti, T.10
Monroe, J.G.11
Atchison, M.L.12
Thomas-Tikhonenko, A.13
-
49
-
-
20444486559
-
An inhibitor of Bcl-2 family proteins induces regression of solid tumours
-
DOI 10.1038/nature03579
-
Oltersdorf T, Elmore SW, Shoemaker AR, et al. An inhibitor of Bcl-2 family proteins induces regression of solid tumours. Nature. 2005;435(7042):677-681. (Pubitemid 40825512)
-
(2005)
Nature
, vol.435
, Issue.7042
, pp. 677-681
-
-
Oltersdorf, T.1
Elmore, S.W.2
Shoemaker, A.R.3
Armstrong, R.C.4
Augeri, D.J.5
Belli, B.A.6
Bruncko, M.7
Deckwerth, T.L.8
Dinges, J.9
Hajduk, P.J.10
Joseph, M.K.11
Kitada, S.12
Korsmeyer, S.J.13
Kunzer, A.R.14
Letai, A.15
Li, C.16
Mitten, M.J.17
Nettesheim, D.G.18
Ng, S.19
Nimmer, P.M.20
O'Connor, J.M.21
Oleksijew, A.22
Petros, A.M.23
Reed, J.C.24
Shen, W.25
Tahir, S.K.26
Thompson, C.B.27
Tomaselli, K.J.28
Wang, B.29
Wendt, M.D.30
Zhang, H.31
Fesik, S.W.32
Rosenberg, S.H.33
more..
-
50
-
-
33845994359
-
Chronic lymphocytic leukemia requires BCL2 to sequester prodeath BIM, explaining sensitivity to BCL2 antagonist ABT-737
-
DOI 10.1172/JCI28281
-
Del Gaizo Moore V, Brown JR, Certo M, Love TM, Novina CD, Letai A. Chronic lymphocytic leukemia requires BCL2 to sequester prodeath BIM, explaining sensitivity to BCL2 antagonist ABT-737. J Clin Invest. 2007;117(1):112-121. (Pubitemid 46048458)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.1
, pp. 112-121
-
-
Moore, V.D.G.1
Brown, J.R.2
Certo, M.3
Love, T.M.4
Novina, C.D.5
Letai, A.6
-
51
-
-
42149113415
-
A novel paradigm for rapid ABT-737-induced apoptosis involving outer mitochondrial membrane rupture in primary leukemia and lymphoma cells
-
DOI 10.1038/cdd.2008.25, PII CDD200825
-
Vogler M, Dinsdale D, Sun XM, et al. A novel paradigm for rapid ABT-737-induced apoptosis involving outer mitochondrial membrane rupture in primary leukemia and lymphoma cells. Cell Death Differ. 2008;15(5):820-830. (Pubitemid 351524424)
-
(2008)
Cell Death and Differentiation
, vol.15
, Issue.5
, pp. 820-830
-
-
Vogler, M.1
Dinsdale, D.2
Sun, X.-M.3
Young, K.W.4
Butterworth, M.5
Nicotera, P.6
Dyer, M.J.S.7
Cohen, G.M.8
|