IP3 receptor-binding partners in cell-death mechanisms

Wiley Interdisciplinary Reviews: Membrane Transport and Signaling

Volumn 1, Issue 2, 2012, Pages 201-210

  Kiviluoto, Santeri ^a   Akl, Haidar ^a   Vervliet, Tim ^a   Bultynck, Geert ^a   Parys, Jan B ^a   Missiaen, Ludwig ^a   De Smedt, Humbert ^a  

^a LABORATORY OF MOLECULAR AND CELLULAR SIGNALING   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; VOLTAGE DEPENDENT ANION CHANNEL;

ADAPTATION; ALZHEIMER DISEASE; ARTICLE; CALCIUM SIGNALING; CALCIUM TRANSPORT; CELL DEATH; CELL ENERGY; CELL METABOLISM; CELL SURVIVAL; ENDOPLASMIC RETICULUM STRESS; FAMILIAL DISEASE; HUMAN; HUNTINGTON CHOREA; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; MITOPHAGY; MOLECULAR DYNAMICS; MOLECULAR PATHOLOGY; NERVE CELL LESION; NONHUMAN; OUTER MITOCHONDRIAL MEMBRANE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RECEPTOR BINDING;

EID: 84872570280     PISSN: 2190460X     EISSN: 21904618     Source Type: Journal    
DOI: 10.1002/wmts.5     Document Type: Article

References (98)

1. Berridge MJ, Bootman MD, Roderick HL. Calcium signalling: dynamics, homeostasis and remodelling. Nat Rev Mol Cell Biol 2003, 4:517-529.
2. Orrenius S, Nicotera P, Zhivotovsky B. Cell death mechanisms and their implications in toxicology. Toxicol Sci 2011, 119:3-19.
3. 2+ channel and its cellular function. Biochem Soc Symp 2007, 74:9-22.
4. 2+ release channels. Physiol Rev 2007, 87:593-658.
5. Taylor CW, Rahman T, Tovey SC, Dedos SG, Taylor EJ, Velamakanni S. IP3 receptors: some lessons from DT40 cells. Immunol Rev 2009, 231:23-44.
6. 2+ release and beyond. Apoptosis 2007, 12:951-968.
7. Decuypere JP, Monaco G, Bultynck G, Missiaen L, Smedt HD, Parys JB. The IP3 receptor-mitochondria connection in apoptosis and autophagy. Biochim Biophys Acta 2011, 1813:1003-1013.
8. Sugawara H, Kurosaki M, Takata M, Kurosaki T. Genetic evidence for involvement of type 1, type 2 and type 3 inositol 1, 4, 5-trisphosphate receptors in signal transduction through the B-cell antigen receptor. Embo J 1997, 16:3078-3088.
9. 2+ transfer to mitochondria. Cell 2010, 142:270-283.
10. Bernardi P, Rasola A. Calcium and cell death: the mitochondrial connection. Subcell Biochem 2007, 45: 481-506.
11. Harr MW, Distelhorst CW. Apoptosis and autophagy: decoding calcium signals that mediate life or death. Cold Spring Harb Perspect Biol 2010, 2:a005579.
12. Giorgi C, De Stefani D, Bononi A, Rizzuto R, Pinton P. Structural and functional link between the mitochondrial network and the endoplasmic reticulum. Int J Biochem Cell Biol 2009, 41:1817-1827.
13. Hayashi T, Rizzuto R, Hajnoczky G, Su TP. MAM: more than just a housekeeper. Trends Cell Biol 2009, 19:81-88.
14. de Brito OM, Scorrano L. An intimate liaison: spatial organization of the endoplasmic reticulum-mitochondria relationship. Embo J 2010, 29: 2715-2723.
15. Csordas G, Varnai P, Golenar T, Roy S, Purkins G, Schneider TG, Balla T, Hajnoczky G. Imaging interorganelle contacts and local calcium dynamics at the ER-mitochondrial interface. Mol Cell 2010, 39:121-132.
16. 2+ channels. J Cell Biol 2006, 175:901-911.
17. Hayashi T, Su TP. Sigma-1 receptor chaperones at the ER-mitochondrion interface regulate Ca(2+) signaling and cell survival. Cell 2007, 131:596-610.
18. Shoshan-Barmatz V, De Pinto V, Zweckstetter M, Raviv Z, Keinan N, Arbel N. VDAC, a multi-functional mitochondrial protein regulating cell life and death. Mol Aspects Med 2010, 31:227-285.
19. 2+ from sarcoplasmic reticulum to mitochondria in rat ventricular myocytes. J Bioenerg Biomembr 2000, 32:97-104.
20. Szalai G, Csordas G, Hantash BM, Thomas AP, Hajnoczky G. Calcium signal transmission between ryanodine receptors and mitochondria. J Biol Chem 2000, 275:15305-15313.
21. Robert V, Massimino ML, Tosello V, Marsault R, Cantini M, Sorrentino V, Pozzan T. Alteration in calcium handling at the subcellular level in mdx myotubes. J Biol Chem 2001, 276:4647-4651.
22. Rudolf R, Mongillo M, Magalhaes PJ, Pozzan T. In vivo monitoring of Ca(2+) uptake into mitochondria of mouse skeletal muscle during contraction. J Cell Biol 2004, 166:527-536.
23. 2+ transfer between sarcoplasmic reticulum subdomains and the mitochondria in heart muscle. J Biol Chem 2008, 283:32771-32780.
24. Hajnoczky G, Csordas G, Yi M. Old players in a new role: mitochondria-associated membranes, VDAC, and ryanodine receptors as contributors to calcium signal propagation from endoplasmic reticulum to the mitochondria. Cell Calcium 2002, 32:363-377.
25. Baines CP, Kaiser RA, Sheiko T, Craigen WJ, Molkentin JD. Voltage-dependent anion channels are dispensable for mitochondrial-dependent cell death. Nat Cell Biol 2007, 9:550-555.
26. Hirota J, Furuichi T, Mikoshiba K. Inositol 1, 4, 5-trisphosphate receptor type 1 is a substrate for caspase-3 and is cleaved during apoptosis in a caspase-3-dependent manner. J Biol Chem 1999, 274: 34433-34437.
27. Nakayama T, Hattori M, Uchida K, Nakamura T, Tateishi Y, Bannai H, Iwai M, Michikawa T, Inoue T, Mikoshiba K. The regulatory domain of the inositol 1, 4, 5-trisphosphate receptor is necessary to keep the channel domain closed: possible physiological significance of specific cleavage by caspase 3. Biochem J 2004, 377(Pt 2):299-307.
28. Assefa Z, Bultynck G, Szlufcik K, Nadif Kasri N, Vermassen E, Goris J, Missiaen L, Callewaert G, Parys JB, De Smedt H. Caspase-3-induced truncation of type 1 inositol trisphosphate receptor accelerates apoptotic cell death and induces inositol trisphosphate-independent calcium release during apoptosis. J Biol Chem 2004, 279:43227-43236.
29. Boehning D, Patterson RL, Sedaghat L, Glebova NO, Kurosaki T, Snyder SH. Cytochrome c binds to inositol (1, 4, 5) trisphosphate receptors, amplifying calcium-dependent apoptosis. Nat Cell Biol 2003, 5: 1051-1061.
30. Boehning D, van Rossum DB, Patterson RL, Snyder SH. A peptide inhibitor of cytochrome c/inositol 1, 4, 5-trisphosphate receptor binding blocks intrinsic and extrinsic cell death pathways. Proc Natl Acad Sci U S A 2005, 102:1466-1471.
31. 2+ release via locally derived NADH. Proc Natl Acad Sci U S A 2005, 102: 1357-1359.
32. 2+ signal regulation. J Biol Chem 2009, 284:29158-29169.
33. 2+ for cancer cell proliferation and survival. Nat Rev Cancer 2008, 8:361-375.
34. Khan MT, Wagner L, 2nd, Yule DI, Bhanumathy C, Joseph SK. Akt kinase phosphorylation of inositol 1, 4, 5-trisphosphate receptors. J Biol Chem 2006, 281: 3731-3737.
35. 2+ release and apoptosis. Proc Natl Acad Sci U S A 2008, 105:2427-2432.
36. 2+-dependent apoptotic stimuli. Biochem Biophys Res Commun 2008, 375: 501-505.
37. Giorgi C, Ito K, Lin HK, Santangelo C, Wieckowski MR, Lebiedzinska M, Bononi A, Bonora M, Duszynski J, Bernardi R, et al. PML regulates apoptosis at endoplasmic reticulum by modulating calcium release. Science 2010, 330:1247-1251.
38. 2+: a control point for apoptosis. Science 2003, 300:135-139.
39. Oakes SA, Scorrano L, Opferman JT, Bassik MC, Nishino M, Pozzan T, Korsmeyer SJ. Proapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulum. Proc Natl Acad Sci U S A 2005, 102:105-110.
40. Distelhorst CW, Shore GC. Bcl-2 and calcium: controversy beneath the surface. Oncogene 2004, 23: 2875-2880.
41. Szegezdi E, Macdonald DC, Ni Chonghaile T, Gupta S, Samali A. Bcl-2 family on guard at the ER. Am J Physiol Cell Physiol 2009, 296:C941-C953.
42. 2+ storage in health and disease: a dynamic equilibrium. Cell Calcium 2010, 47: 297-314.
43. Chen R, Valencia I, Zhong F, McColl KS, Roderick HL, Bootman MD, Berridge MJ, Conway SJ, Holmes AB, Mignery GA, et al. Bcl-2 functionally interacts with inositol 1, 4, 5-trisphosphate receptors to regulate calcium release from the ER in response to inositol 1, 4, 5-trisphosphate. J Cell Biol 2004, 166:193-203.
44. White C, Li C, Yang J, Petrenko NB, Madesh M, Thompson CB, Foskett JK. The endoplasmic reticulum gateway to apoptosis by Bcl-X(L) modulation of the InsP3R. Nat Cell Biol 2005, 7:1021-1028.
45. Chae HJ, Ke N, Kim HR, Chen S, Godzik A, Dickman M, Reed JC. Evolutionarily conserved cytoprotection provided by Bax Inhibitor-1 homologs from animals, plants, and yeast. Gene 2003, 323:101-113.
46. Chae HJ, Kim HR, Xu C, Bailly-Maitre B, Krajewska M, Krajewski S, Banares S, Cui J, Digicaylioglu M, Ke N, et al. BI-1 regulates an apoptosis pathway linked to endoplasmic reticulum stress. Mol Cell 2004, 15: 355-366.
47. Berridge MJ. Calcium hypothesis of Alzheimer's disease. Pflugers Arch 2010, 459:441-449.
48. 2+ homeostasis downstream of Bcl-2 family proteins. J Biol Chem 2008, 283: 11477-11484.
49. de Mattia F, Gubser C, van Dommelen MM, Visch HJ, Distelmaier F, Postigo A, Luyten T, Parys JB, de Smedt H, Smith GL, et al. Human Golgi antiapoptotic protein modulates intracellular calcium fluxes. Mol Biol Cell 2009, 20:3638-3645.
50. Xu Q, Reed JC. Bax inhibitor-1, a mammalian apoptosis suppressor identified by functional screening in yeast. Mol Cell 1998, 1:337-346.
51. Westphalen BC, Wessig J, Leypoldt F, Arnold S, Methner A. BI-1 protects cells from oxygen glucose deprivation by reducing the calcium content of the endoplasmic reticulum. Cell Death Differ 2005, 12:304-306.
52. Lisbona F, Rojas-Rivera D, Thielen P, Zamorano S, Todd D, Martinon F, Glavic A, Kress C, Lin JH, Walter P, et al. BAX inhibitor-1 is a negative regulator of the ER stress sensor IRE1alpha. Mol Cell 2009, 33: 679-691.
53. Rong J, Chen L, Toth JI, Tcherpakov M, Petroski MD, Reed JC. Bifunctional apoptosis regulator (BAR), an Endoplasmic reticulum (ER)-associated E3 ubiquitin ligase, modulates BI-1 protein stability and function in ER stress. J Biol Chem 2011, 286:1453-1463.
54. van Kuppeveld FJ, de Jong AS, Melchers WJ, Willems PH. Enterovirus protein 2B po(u)res out the calcium: a viral strategy to survive? Trends Microbiol 2005, 13:41-44.
55. Higo T, Hamada K, Hisatsune C, Nukina N, Hashi- kawa T, Hattori M, Nakamura T, Mikoshiba K. Mechanism of ER stress-induced brain damage by IP(3) receptor. Neuron 2010, 68:865-878.
56. Zhu L, Ling S, Yu XD, Venkatesh LK, Subramanian T, Cninnadurai G, Kuo TH. Modulation of mitochondrial Ca(2+) homeostasis by Bcl-2. J Biol Chem 1999, 274:33267-33273.
57. 2+ release is inhibited by mitochondrial depolarization. Biochem J 2000, 347(Pt 2):593-600.
58. Higo T, Hattori M, Nakamura T, Natsume T, Michi- kawa T, Mikoshiba K. Subtype-specific and ER lumenal environment-dependent regulation of inositol 1, 4, 5-trisphosphate receptor type 1 by ERp44. Cell 2005, 120:85-98.
59. Li G, Mongillo M, Chin KT, Harding H, Ron D, Marks AR, Tabas I. Role of ERO1-alpha-mediated stimulation of inositol 1, 4, 5-triphosphate receptor activity in endoplasmic reticulum stress-induced apoptosis. J Cell Biol 2009, 186:783-792.
60. 2+ signals according to the strength of T cell receptor activation. J Cell Biol 2006, 172:127-137.
61. Rong YP, Aromolaran AS, Bultynck G, Zhong F, Li X, De Smedt H, Mignery GA, Roderick HL, Bootman MD, Distelhorst CW. Targeting Bcl-2-IP3 receptor interaction to reverse Bcl-2's inhibition of apoptotic calcium signals. Mol Cell 2008, 31:255-265.
62. Rong YP, Bultynck G, Aromolaran AS, Zhong F, Parys JB, De Smedt H, Mignery GA, Roderick HL, Bootman MD, Distelhorst CW. The BH4 domain of Bcl-2 inhibits ER calcium release and apoptosis by binding the regulatory and coupling domain of the IP3 receptor. Proc Natl Acad Sci U S A 2009, 106:14397-14402.
63. Chipuk JE, Moldoveanu T, Llambi F, Parsons MJ, Green DR. The BCL-2 family reunion. Mol Cell 2010, 37:299-310.
64. Li C, Wang X, Vais H, Thompson CB, Foskett JK, White C. Apoptosis regulation by Bcl-x(L) modulation of mammalian inositol 1, 4, 5-trisphosphate receptor channel isoform gating. Proc Natl Acad Sci U S A 2007, 104:12565-12570.
65. 2+ signaling. J Biol Chem 2010, 285: 13678-13684.
66. Klionsky DJ. Autophagy: from phenomenology to molecular understanding in less than a decade. Nat Rev Mol Cell Biol 2007, 8:931-937.
67. Kroemer G, Levine B. Autophagic cell death: the story of a misnomer. Nat Rev Mol Cell Biol 2008, 9: 1004-1010.
68. Criollo A, Maiuri MC, Tasdemir E, Vitale I, Fiebig AA, Andrews D, Molgo J, Diaz J, Lavandero S, Harper F, et al. Regulation of autophagy by the inositol trisphosphate receptor. Cell Death Differ 2007, 14:1029-1039.
69. Khan MT, Joseph SK. Role of inositol trisphosphate receptors in autophagy in DT40 cells. J Biol Chem 2010, 285:16912-16920.
70. Vicencio JM, Ortiz C, Criollo A, Jones AW, Kepp O, Galluzzi L, Joza N, Vitale I, Morselli E, Tailler M, et al. The inositol 1, 4, 5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1. Cell Death Differ 2009, 16:1006-1017.
71. Hoyer-Hansen M, Bastholm L, Szyniarowski P, Campanella M, Szabadkai G, Farkas T, Bianchi K, Fehrenbacher N, Elling F, Rizzuto R, et al. Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-beta, and Bcl-2. Mol Cell 2007, 25:193-205.
72. Swerdlow S, Distelhorst CW. Bcl-2-regulated calcium signals as common mediators of both apoptosis and autophagy. Dev Cell 2007, 12:178-179.
73. Chang NC, Nguyen M, Germain M, Shore GC. Antagonism of Beclin 1-dependent autophagy by BCL-2 at the endoplasmic reticulum requires NAF-1. Embo J 2010, 29:606-618.
74. Levine B, Sinha S, Kroemer G. Bcl-2 family members: dual regulators of apoptosis and autophagy. Autophagy 2008, 4:600-606.
75. Maiuri MC, Criollo A, Kroemer G. Crosstalk between apoptosis and autophagy within the Beclin 1 interactome. Embo J 2010, 29:515-516.
76. 2+, autophagy and protein degradation: thrown off balance in neurodegenerative disease. Cell Calcium 2010, 47: 112-121.
77. Danial NN, Korsmeyer SJ. Cell death: critical control points. Cell 2004, 116:205-219.
78. Deng J, Carlson N, Takeyama K, Dal Cin P, Shipp M, Letai A. BH3 profiling identifies three distinct classes of apoptotic blocks to predict response to ABT-737 and conventional chemotherapeutic agents. Cancer Cell 2007, 12:171-185.
79. Chonghaile TN, Letai A. Mimicking the BH3 domain to kill cancer cells. Oncogene 2008, 27(Suppl 1): S149-157.
80. Rong Y, Distelhorst CW. Bcl-2 protein family members: versatile regulators of calcium signaling in cell survival and apoptosis. Annu Rev Physiol 2008, 70:73-91.
81. 2+-driven apoptosis in chronic lymphocytic leukemia cells by peptide-mediated disruption of Bcl-2-IP3 receptor interaction. Blood 2011, 117:2924-2934.
82. Rong YP, Barr P, Yee VC, Distelhorst CW. Targeting Bcl-2 based on the interaction of its BH4 domain with the inositol 1, 4, 5-trisphosphate receptor. Biochim Biophys Acta 2009, 1793:971-978.
83. Toescu EC, Verkhratsky A. Role of calcium in normal aging and neurodegeneration. Aging Cell 2007, 6:265.
84. Bezprozvanny I. Calcium signaling and neurodegenerative diseases. Trends Mol Med 2009, 15:89-100.
85. 2+ channel: from discovery to new signaling concepts. J Neurochem 2007, 102:1426-1446.
86. Mattson MP. ER calcium and Alzheimer's disease: in a state of flux. Sci Signal 2010, 3:pe10.
87. 2+ leak channels, a function disrupted by familial Alzheimer's disease-linked mutations. Cell 2006, 126:981-993.
88. 2+ disruption in Alzheimer's disease by presenilin regulation of InsP3 receptor channel gating. Neuron 2008, 58:871-883.
89. Cheung KH, Mei L, Mak DO, Hayashi I, Iwatsubo T, Kang DE, Foskett JK. Gain-of-function enhancement of IP3 receptor modal gating by familial Alzheimer's disease-linked presenilin mutants in human cells and mouse neurons. Sci Signal 2010, 3:ra22.
90. Muller M, Cheung KH, Foskett JK. Enhanced ROS generation mediated by Alzheimer's disease presenilin regulation of InsP(3)R Ca(2+) signaling. Antioxid Redox Signal 2011, 14:1225-1235.
91. Leissring MA, LaFerla FM, Callamaras N, Parker I. Subcellular mechanisms of presenilin-mediated enhancement of calcium signaling. Neurobiol Dis 2001, 8: 469-478.
92. Tang TS, Tu H, Chan EY, Maximov A, Wang Z, Wellington CL, Hayden MR, Bezprozvanny I. Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1, 4, 5) triphosphate receptor type 1. Neuron 2003, 39:227-239.
93. Bezprozvanny I. Inositol 1, 4, 5-tripshosphate receptor, calcium signalling and Huntington's disease. Subcell Biochem 2007, 45:323-335.
94. Tang TS, Guo C, Wang H, Chen X, Bezprozvanny I. Neuroprotective effects of inositol 1, 4, 5-trisphosphate receptor C-terminal fragment in a Huntington's disease mouse model. J Neurosci 2009, 29:1257-1266.
95. Liu J, Tang TS, Tu H, Nelson O, Herndon E, Huynh DP, Pulst SM, Bezprozvanny I. Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 2. J Neurosci 2009, 29:9148-9162.
96. Chen X, Tang TS, Tu H, Nelson O, Pook M, Hammer R, Nukina N, Bezprozvanny I. Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 3. J Neurosci 2008, 28:12713-12724.
97. Kasumu A, Bezprozvanny I. Deranged calcium signaling in purkinje cells and pathogenesis in spinocerebellar ataxia 2 (SCA2) and other ataxias. Cerebellum 2010. doi:10.1007/s12311-010-0182-9.
98. Bezprozvanny I. Role of inositol 1, 4, 5-trishosphate receptors in pathogenesis of huntington's disease and spinocerebellar ataxias. Neurochem Res 2011, 36:1186-1197.