Calcium channels and pumps in cancer: Changes and consequences

Journal of Biological Chemistry

Volumn 287, Issue 38, 2012, Pages 31666-31673

  Monteith, Gregory R ^a   Davis, Felicity M ^a   Roberts Thomson, Sarah J ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNELS; CELLULAR PROCESS; IN-PROCESS; SUBCELLULAR ORGANELLES; THERAPEUTIC TARGETS;

CELL MEMBRANES; DIAGNOSIS; DISEASES;

CALCIUM;

ADENOSINE TRIPHOSPHATASE (CALCIUM); CALCIUM CHANNEL; REGULATOR PROTEIN;

CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CALCIUM SIGNALING; CALCIUM TRANSPORT; CANCER CELL CULTURE; CANCER PROGNOSIS; CELL MEMBRANE TRANSPORT; CELL MIGRATION; CELL ORGANELLE; CELL PROLIFERATION; ENDOPLASMIC RETICULUM; GOLGI COMPLEX; HUMAN; MALIGNANT NEOPLASTIC DISEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; SHORT SURVEY;

ANIMALS; APOPTOSIS; BIOLOGICAL TRANSPORT; CALCIUM; CALCIUM CHANNELS; CALCIUM SIGNALING; CALCIUM-TRANSPORTING ATPASES; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MODELS, BIOLOGICAL; NEOPLASMS; PROGNOSIS;

EID: 84866367672     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.R112.343061     Document Type: Short Survey

References (100)

1. Hanahan, D., and Weinberg, R. A. (2000) The hallmarks of cancer. Cell 100, 57-70 (Pubitemid 30046295)
2. 2+ for cancer cell proliferation and survival. Nat. Rev. Cancer 8, 361-375
3. Prevarskaya, N., Skryma, R., and Shuba, Y. (2011) Calcium in tumor metastasis: new roles for known actors. Nat. Rev. Cancer 11, 609-618
4. Fiorio Pla, A., Avanzato, D., Munaron, L., and Ambudkar, I. S. (2012) Ion channels and transporters in cancer. 6. Vascularizing the tumor: TRP channels as molecular targets. Am. J. Physiol. Cell Physiol. 302, C9-C15
5. Rizzuto, R., Pinton, P., Ferrari, D., Chami, M., Szabadkai, G., Magalhães, P. J., Di Virgilio, F., and Pozzan, T. (2003) Calcium and apoptosis: facts and hypotheses. Oncogene 22, 8619-8627 (Pubitemid 38019197)
6. Lehen'kyi, V., Shapovalov, G., Skryma, R., and Prevarskaya, N. (2011) Ion channnels and transporters in cancer. 5. Ion channels in control of cancer and cell apoptosis. Am. J. Physiol. Cell Physiol. 301, C1281-C1289
7. Ramsey, I. S., Delling, M., and Clapham, D. E. (2006) An introduction to TRP channels. Annu. Rev. Physiol. 68, 619-647
8. Tsavaler, L., Shapero, M. H., Morkowski, S., and Laus, R. (2001) Trp-p8, a novel prostate-specific gene, is up-regulated in prostate cancer and other malignancies and shares high homology with transient receptor potential calcium channel proteins. Cancer Res. 61, 3760-3769 (Pubitemid 32694990)
9. McKemy, D. D., Neuhausser, W. M., and Julius, D. (2002) Identification of a cold receptor reveals a general role for TRP channels in thermosensation. Nature 416, 52-58 (Pubitemid 34215395)
10. Knowlton, W. M., Daniels, R. L., Palkar, R., McCoy, D. D., and McKemy, D. D. (2011) Pharmacological blockade of TRPM8 ion channels alters cold and cold pain responses in mice. PLoS ONE 6, e25894
11. 2+ channel required for the survival of prostate cancer cells. Cancer Res. 64, 8365-8373
12. 2+ transport. Nat. Rev. Cancer 7, 519-530
13. Gkika, D., Flourakis, M., Lemonnier, L., and Prevarskaya, N. (2010) PSA reduces prostate cancer cell motility by stimulating TRPM8 activity and plasma membrane expression. Oncogene 29, 4611-4616
14. Bidaux, G., Roudbaraki, M., Merle, C., Crépin, A., Delcourt, P., Slomianny, C., Thebault, S., Bonnal, J. L., Benahmed, M., Cabon, F., Mauroy, B., and Prevarskaya, N. (2005) Evidence for specific TRPM8 expression in human prostate secretory epithelial cells: functional androgen receptor requirement. Endocr. Relat. Cancer 12, 367-382 (Pubitemid 40903086)
15. Bidaux, G., Flourakis, M., Thebault, S., Zholos, A., Beck, B., Gkika, D., Roudbaraki, M., Bonnal, J. L., Mauroy, B., Shuba, Y., Skryma, R., and Prevarskaya, N. (2007) Prostate cell differentiation status determines transient receptor potential melastatin member 8 channel subcellular localization and function. J. Clin. Invest. 117, 1647-1657 (Pubitemid 46871349)
16. Henshall, S. M., Afar, D. E., Hiller, J., Horvath, L. G., Quinn, D. I., Rasiah, K. K., Gish, K., Willhite, D., Kench, J. G., Gardiner-Garden, M., Stricker, P. D., Scher, H. I., Grygiel, J. J., Agus, D. B., Mack, D. H., and Sutherland, R. L. (2003) Survival analysis of genome-wide gene expression profiles of prostate cancers identifies new prognostic targets of disease relapse. Cancer Res. 63, 4196-4203 (Pubitemid 36917946)
17. Prevarskaya, N., Skryma, R., Bidaux, G., Flourakis, M., and Shuba, Y. (2007) Ion channels in death and differentiation of prostate cancer cells. Cell Death Differ. 14, 1295-1304 (Pubitemid 46965260)
18. 2+-selective cation channel TRPV6 in human prostate cancer: a novel prognostic marker for tumor progression. Oncogene 22, 7858-7861
19. 2+/NFAT-dependent pathways. Oncogene 26, 7380-7385
20. Wissenbach, U., and Niemeyer, B. A. (2007) Trpv6. Handb. Exp. Pharmacol. 179, 221-234
21. Bolanz, K. A., Hediger, M. A., and Landowski, C. P. (2008) The role of TRPV6 in breast carcinogenesis. Mol. Cancer Ther. 7, 271-279 (Pubitemid 351302521)
22. Aydar, E., Yeo, S., Djamgoz, M., and Palmer, C. (2009) Abnormal expression, localization, and interaction of canonical transient receptor potential ion channels in human breast cancer cell lines and tissues: a potential target for breast cancer diagnosis and therapy. Cancer Cell Int. 9, 23
23. Yang, S. L., Cao, Q., Zhou, K. C., Feng, Y. J., and Wang, Y. Z. (2009) Transient receptor potential channel C3 contributes to the progression of human ovarian cancer. Oncogene 28, 1320-1328
24. Shi, Y., Ding, X., He, Z. H., Zhou, K. C., Wang, Q., and Wang, Y. Z. (2009) Critical role of TRPC6 channels in G2 phase transition and the development of human esophageal cancer. Gut 58, 1443-1450
25. 2/M phase transition and development of human glioma. J. Natl. Cancer Inst. 102, 1052-1068
26. Fiorio Pla, A., Ong, H. L., Cheng, K. T., Brossa, A., Bussolati, B., Lockwich, T., Paria, B., Munaron, L., and Ambudkar, I. S. (2012) TRPV4 mediates tumor-derived endothelial cell migration via arachidonic acid-activated actin remodeling. Oncogene 31, 200-212
27. Wei, C., Wang, X., Chen, M., Ouyang, K., Song, L. S., and Cheng, H. (2009) Calcium flickers steer cell migration. Nature 457, 901-905
28. Numata, T., Shimizu, T., and Okada, Y. (2007) TRPM7 is a stretch- and swelling-activated cation channel involved in volume regulation in human epithelial cells. Am. J. Physiol. Cell Physiol. 292, C460-C467 (Pubitemid 46115154)
29. Rybarczyk, P., Gautier, M., Hague, F., Dhennin-Duthille, I., Chatelain, D., Kerr-Conte, J., Pattou, F., Regimbeau, J. M., Sevestre, H., and Ouadid-Ahidouch, H. (2012) Transient receptor potential melastatin-related 7 channel is overexpressed in human pancreatic ductal adenocarcinomas and regulates human pancreatic cancer cell migration. Int. J. Cancer 131, E851-E861
30. Gao, H., Chen, X., Du, X., Guan, B., Liu, Y., and Zhang, H. (2011) EGF enhances the migration of cancer cells by up-regulation of TRPM7. Cell Calcium 50, 559-568
31. 2+ influx. Cell Calcium 47, 425-432
32. Parekh, A. B., and Putney, J. W., Jr. (2005) Store-operated calcium channels. Physiol. Rev. 85, 757-810 (Pubitemid 40404641)
33. Roberts-Thomson, S. J., Peters, A. A., Grice, D. M., and Monteith, G. R. (2010) ORAI-mediated calcium entry: mechanism and roles, diseases and pharmacology. Pharmacol. Ther. 127, 121-130
34. Hogan, P. G., and Rao, A. (2007) Dissecting ICRAC, a store-operated calcium current. Trends Biochem. Sci. 32, 235-245 (Pubitemid 46694334)
35. Feske, S., Gwack, Y., Prakriya, M., Srikanth, S., Puppel, S. H., Tanasa, B., Hogan, P. G., Lewis, R. S., Daly, M., and Rao, A. (2006) A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function. Nature 441, 179-185
36. Roos, J., DiGregorio, P. J., Yeromin, A. V., Ohlsen, K., Lioudyno, M., Zhang, S., Safrina, O., Kozak, J. A., Wagner, S. L., Cahalan, M. D., Veliçelebi, G., and Stauderman, K. A. (2005) STIM1, an essential and conserved component of store-operated Ca2+ channel function. J. Cell Biol. 169, 435-445 (Pubitemid 40686694)
37. McAndrew, D., Grice, D. M., Peters, A. A., Davis, F. M., Stewart, T., Rice, M., Smart, C. E., Brown, M. A., Kenny, P. A., Roberts-Thomson, S. J., and Monteith, G. R. (2011) ORAI1-mediated calcium influx in lactation and in breast cancer. Mol. Cancer Ther. 10, 448-460
38. Yang, S., Zhang, J. J., and Huang, X. Y. (2009) Orai1 and STIM1 are critical for breast tumor cell migration and metastasis. Cancer Cell 15, 124-134
39. Feng, M., Grice, D. M., Faddy, H. M., Nguyen, N., Leitch, S., Wang, Y., Muend, S., Kenny, P. A., Sukumar, S., Roberts-Thomson, S. J., Monteith, G. R., and Rao, R. (2010) Store-independent activation of Orai1 by SPCA2 in mammary tumors. Cell 143, 84-98
40. Chen, Y. F., Chiu, W. T., Chen, Y. T., Lin, P. Y., Huang, H. J., Chou, C. Y., Chang, H. C., Tang, M. J., and Shen, M. R. (2011) Calcium store sensor stromal interaction molecule 1-dependent signaling plays an important role in cervical cancer growth, migration, and angiogenesis. Proc. Natl. Acad. Sci. U.S.A. 108, 15225-15230
41. Motiani, R. K., Abdullaev, I. F., and Trebak, M. (2010) A novel native store-operated calcium channel encoded by Orai3: selective requirement of Orai3 versus Orai1 in estrogen receptor-positive versus estrogen receptor-negative breast cancer cells. J. Biol. Chem. 285, 19173-19183
42. Faouzi, M., Hague, F., Potier, M., Ahidouch, A., Sevestre, H., and Ouadid-Ahidouch, H. (2011) Down-regulation of Orai3 arrests cell cycle progression and induces apoptosis in breast cancer cells but not in normal breast epithelial cells. J. Cell. Physiol. 226, 542-551
43. Flourakis, M., Lehen'kyi, V., Beck, B., Raphaël, M., Vandenberghe, M., Abeele, F. V., Roudbaraki, M., Lepage, G., Mauroy, B., Romanin, C., Shuba, Y., Skryma, R., and Prevarskaya, N. (2010) Orai1 contributes to the establishment of an apoptosis-resistant phenotype in prostate cancer cells. Cell Death Dis. 1, e75
44. Natrajan, R., Little, S. E., Reis-Filho, J. S., Hing, L., Messahel, B., Grundy, P. E., Dome, J. S., Schneider, T., Vujanic, G. M., Pritchard-Jones, K., and Jones, C. (2006) Amplification and overexpression of CACNA1E correlates with relapse in favorable histology Wilms tumors. Clin. Cancer Res. 12, 7284-7293 (Pubitemid 46095400)
45. Wanajo, A., Sasaki, A., Nagasaki, H., Shimada, S., Otsubo, T., Owaki, S., Shimizu, Y., Eishi, Y., Kojima, K., Nakajima, Y., Kawano, T., Yuasa, Y., and Akiyama, Y. (2008) Methylation of the calcium channel-related gene CACNA2D3 is frequent and a poor prognostic factor in gastric cancer. Gastroenterology 135, 580-590
46. Strehler, E. E., and Zacharias, D. A. (2001) Role of alternative splicing in generating isoform diversity among plasma membrane calcium pumps. Physiol. Rev. 81, 21-50 (Pubitemid 32096172)
47. Brini, M., and Carafoli, E. (2009) Calcium pumps in health and disease. Physiol. Rev. 89, 1341-1378
48. 2+-ATPase isoform 2 impairs calcium transport into milk. J. Biol. Chem. 279, 42369-42373
49. 2+ pump isoforms in intact cells. J. Biol. Chem. 278, 24500-24508
50. 2+ concentration of the endoplasmic reticulum is a key determinant of ceramide-induced apoptosis: significance for the molecular mechanism of Bcl-2 action. EMBO J. 20, 2690-2701
51. VanHouten, J., Sullivan, C., Bazinet, C., Ryoo, T., Camp, R., Rimm, D. L., Chung, G., and Wysolmerski, J. (2010) PMCA2 regulates apoptosis during mammary gland involution and predicts outcome in breast cancer. Proc. Natl. Acad. Sci. U.S.A. 107, 11405-11410
52. Lee, W. J., Roberts-Thomson, S. J., and Monteith, G. R. (2005) Plasma membrane calcium ATPases 2 and 4 in human breast cancer cell lines. Biochem. Biophys. Res. Commun. 337, 779-783 (Pubitemid 41446982)
53. 2+-ATPase expression during colon and gastric cancer cell differentiation. Cell Calcium 42, 590-605
54. 2+-ATPase expression during colon cancer cell line differentiation. Biochem. Biophys. Res. Commun. 355, 932-936
55. Aung, C. S., Ye, W., Plowman, G., Peters, A. A., Monteith, G. R., and Roberts-Thomson, S. J. (2009) Plasma membrane calcium ATPase 4 and the remodeling of calcium homeostasis in human colon cancer cells. Carcinogenesis 30, 1962-1969
56. De Stefani, D., Raffaello, A., Teardo, E., Szabò, I., and Rizzuto, R. (2011)A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter. Nature 476, 336-340
57. 2+ exchange. Proc. Natl. Acad. Sci. U.S.A. 107, 436-441
58. Drago, I., Pizzo, P., and Pozzan, T. (2011) After half a century mitochondrial calcium in- and efflux machineries reveal themselves. EMBO J. 30, 4119-4125
59. Zhu, M. X., Ma, J., Parrington, J., Calcraft, P. J., Galione, A., and Evans, A. M. (2010) Calcium signaling via two-pore channels: local or global, that is the question. Am. J. Physiol. Cell Physiol. 298, C430-C441
60. Wenner, C. E. (2012) Targeting mitochondria as a therapeutic target in cancer. J. Cell. Physiol. 227, 450-456
61. Cotter, T. G. (2009) Apoptosis and cancer: the genesis of a research field. Nat. Rev. Cancer 9, 501-507
62. Cory, S., and Adams, J. M. (2002) The Bcl-2 family: regulators of the cellular life-or-death switch. Nat. Rev. Cancer 2, 647-656 (Pubitemid 37328916)
63. Yang, J., Liu, X., Bhalla, K., Kim, C. N., Ibrado, A. M., Cai, J., Peng, T. I., Jones, D. P., and Wang, X. (1997) Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. Science 275, 1129-1132 (Pubitemid 27097312)
64. 2+ influx in Bcl-2-overexpressing cells. J. Cell Biol. 148, 857-862
65. 2+ analyzed with an improved genetically encoded fluorescent sensor. Proc. Natl. Acad. Sci. U.S.A. 101, 17404-17409
66. 3 receptor interaction to reverse Bcl-2 inhibition of apoptotic calcium signals. Mol. Cell 31, 255-265
67. 2+ as a key regulator of cell life and death. Cell Death Differ. 14, 1267-1274
68. Gélébart, P., Kovács, T., Brouland, J. P., van Gorp, R., Grossmann, J., Rivard, N., Panis, Y., Martin, V., Bredoux, R., Enouf, J., and Papp, B. (2002) Expression of endomembrane calcium pumps in colon and gastric cancer cells. Induction of SERCA3 expression during differentiation. J. Biol. Chem. 277, 26310-26320 (Pubitemid 34967122)
69. Papp, B., and Brouland, J. P. (2011) Altered endoplasmic reticulum calcium pump expression during breast tumorigenesis. Breast Cancer 5, 163-174
70. 2+ pump, predisposes mice to squamous cell tumors via a novel mode of cancer susceptibility. Cancer Res. 65, 8655-8661
71. 2+ pump. J. Biol. Chem. 276, 26737-26740
72. 2+-ATPase, hSPCA2, has unusual properties and is expressed in the brain. J. Biol. Chem. 280, 11608-11614
73. 2+ pumps in the Golgi apparatus. Biochim. Biophys. Acta 1742, 103-112
74. Grice, D. M., Vetter, I., Faddy, H. M., Kenny, P. A., Roberts-Thomson, S. J., and Monteith, G. R. (2010) Golgi calcium pump secretory pathway calcium ATPase 1 (SPCA1) is a key regulator of insulin-like growth factor receptor (IGF1R) processing in the basal-like breast cancer cell line MDA-MB-231. J. Biol. Chem. 285, 37458-37466
75. 2+-ATPase (SPCA1) in mice causes Golgi stress, apoptosis, and midgestational death in homozygous embryos and squamous cell tumors in adult heterozygotes. J. Biol. Chem. 282, 26517-26527
76. Faddy, H. M., Smart, C. E., Xu, R., Lee, G. Y., Kenny, P. A., Feng, M., Rao, R., Brown, M. A., Bissell, M. J., Roberts-Thomson, S. J., and Monteith, G. R. (2008) Localization of plasma membrane and secretory calcium pumps in the mammary gland. Biochem. Biophys. Res. Commun. 369, 977-981
77. 2+-ATPase type 2. Biochem. Biophys. Res. Commun. 352, 537-542
78. Hanahan, D., and Weinberg, R. A. (2011) Hallmarks of cancer: the next generation. Cell 144, 646-674
79. Koppenol, W. H., Bounds, P. L., and Dang, C. V. (2011) Otto Warburg's contributions to current concepts of cancer metabolism. Nat. Rev. Cancer 11, 325-337
80. Gatenby, R. A., and Gillies, R. J. (2004) Why do cancers have high aerobic glycolysis? Nat. Rev. Cancer 4, 891-899 (Pubitemid 39472955)
81. Amuthan, G., Biswas, G., Ananadatheerthavarada, H. K., Vijayasarathy, C., Shephard, H. M., and Avadhani, N. G. (2002) Mitochondrial stress-induced calcium signaling, phenotypic changes, and invasive behavior in human lung carcinoma A549 cells. Oncogene 21, 7839-7849 (Pubitemid 35398842)
82. Mankad, P., James, A., Siriwardena, A. K., Elliott, A. C., and Bruce, J. I. (2012) Insulin protects pancreatic acinar cells from cytosolic calcium overload and inhibition of the plasma membrane calcium pump. J. Biol. Chem. 287, 1823-1836
83. Bissell, M. J., and Hines, W. C. (2011) Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression. Nat. Med. 17, 320-329
84. Bissell, M. J., and Labarge, M. A. (2005) Context, tissue plasticity, and cancer: are tumor stem cells also regulated by the microenvironment? Cancer Cell 7, 17-23 (Pubitemid 40126379)
85. Roskelley, C. D., and Bissell, M. J. (2002) The dominance of the microenvironment in breast and ovarian cancer. Semin. Cancer Biol. 12, 97-104 (Pubitemid 34680738)
86. Kalluri, R., and Zeisberg, M. (2006) Fibroblasts in cancer. Nat. Rev. Cancer 6, 392-401
87. Murata, T., Mizushima, H., Chinen, I., Moribe, H., Yagi, S., Hoffman, R. M., Kimura, T., Yoshino, K., Ueda, Y., Enomoto, T., and Mekada, E. (2011) HB-EGF and PDGF mediate reciprocal interactions of carcinoma cells with cancer-associated fibroblasts to support progression of uterine cervical cancers. Cancer Res. 71, 6633-6642
88. DeWald, D. B., Torabinejad, J., Samant, R. S., Johnston, D., Erin, N., Shope, J. C., Xie, Y., and Welch, D. R. (2005) Metastasis suppression by breast cancer metastasis suppressor 1 involves reduction of phosphoinositide signaling in MDA-MB-435 breast carcinoma cells. Cancer Res. 65, 713-717 (Pubitemid 40216427)
89. Dhennin-Duthille, I., Gautier, M., Faouzi, M., Guilbert, A., Brevet, M., Vaudry, D., Ahidouch, A., Sevestre, H., and Ouadid-Ahidouch, H. (2011) High expression of transient receptor potential channels in human breast cancer epithelial cells and tissues: correlation with pathological parameters. Cell. Physiol. Biochem. 28, 813-822
90. El Boustany, C., Bidaux, G., Enfissi, A., Delcourt, P., Prevarskaya, N., and Capiod, T. (2008) Capacitative calcium entry and transient receptor potential canonical 6 expression control human hepatoma cell proliferation. Hepatology 47, 2068-2077 (Pubitemid 351945573)
91. Yee, N. S., Zhou, W., and Lee, M. (2010) Transient receptor potential channel TRPM8 is overexpressed and required for cellular proliferation in pancreatic adenocarcinoma. Cancer Lett. 297, 49-55
92. Schmidt, U., Fuessel, S., Koch, R., Baretton, G. B., Lohse, A., Tomasetti, S., Unversucht, S., Froehner, M., Wirth, M. P., and Meye, A. (2006) Quantitative multigene expression profiling of primary prostate cancer. Prostate 66, 1521-1534 (Pubitemid 44465817)
93. Kalogris, C., Caprodossi, S., Amantini, C., Lambertucci, F., Nabissi, M., Morelli, M. B., Farfariello, V., Filosa, A., Emiliozzi, M. C., Mammana, G., and Santoni, G. (2010) Expression of transient receptor potential vanilloid-1 (TRPV1) in urothelial cancers of human bladder: relation to clinicopathological and molecular parameters. Histopathology 57, 744-752
94. Czifra, G., Varga, A., Nyeste, K., Marincsák, R., Tóth, B. I., Kovács, I., Kovács, L., and Bíró, T. (2009) Increased expressions of cannabinoid receptor-1 and transient receptor potential vanilloid-1 in human prostate carcinoma. J. Cancer Res. Clin. Oncol. 135, 507-514
95. Zhuang, L., Peng, J. B., Tou, L., Takanaga, H., Adam, R. M., Hediger, M. A., and Freeman, M. R. (2002) Calcium-selective ion channel, CaT1, is apically localized in gastrointestinal tract epithelia and is aberrantly expressed in human malignancies. Lab. Invest. 82, 1755-1764 (Pubitemid 35462988)
96. Wang, X. T., Nagaba, Y., Cross, H. S., Wrba, F., Zhang, L., and Guggino, S. E. (2000) The mRNA of L-type calcium channel elevated in colon cancer: protein distribution in normal and cancerous colon. Am. J. Pathol. 157, 1549-1562
97. Gackière, F., Bidaux, G., Delcourt, P., Van Coppenolle, F., Katsogiannou, M., Dewailly, E., Bavencoffe, A., Van Chuoï-Mariot, M. T., Mauroy, B., Prevarskaya, N., and Mariot, P. (2008) CaV3.2 T-type calcium channels are involved in calcium-dependent secretion of neuroendocrine prostate cancer cells. J. Biol. Chem. 283, 10162-10173
98. Kang, S. S., Han, K. S., Ku, B. M., Lee, Y. K., Hong, J., Shin, H. Y., Almonte, A. G., Woo, D. H., Brat, D. J., Hwang, E. M., Yoo, S. H., Chung, C. K., Park, S. H., Paek, S. H., Roh, E. J., Lee, S. J., Park, J. Y., Traynelis, S. F., and Lee, C. J. (2010) Caffeine-mediated inhibition of calcium release channel inositol 1,4,5-trisphosphate receptor subtype 3 blocks glioblastoma invasion and extends survival. Cancer Res. 70, 1173-1183
99. Shibao, K., Fiedler, M. J., Nagata, J., Minagawa, N., Hirata, K., Nakayama, Y., Iwakiri, Y., Nathanson, M. H., and Yamaguchi, K. (2010) The type III inositol 1,4,5-trisphosphate receptor is associated with aggressiveness of colorectal carcinoma. Cell Calcium 48, 315-323
100. 2+-ATPase type 2 down-regulated in human oral squamous cell carcinoma. Int. J. Cancer 110, 225-231