Calpain-cleaved type 1 inositol 1,4,5-trisphosphate receptor (InsP 3R1) has InsP 3-independent gating and disrupts intracellular Ca 2+ homeostasis

Journal of Biological Chemistry

Volumn 286, Issue 41, 2011, Pages 35998-36010

  Kopil, Catherine M ^a   Vais, Horia ^a   Cheung, King Ho ^a,b   Siebert, Adam P ^a   Mak, Don On Daniel ^a   Foskett, J Kevin ^a   Neumar, Robert W ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

CALPAINS; CARBOXYL-TERMINAL; CARDIAC ARREST; CEREBELLAR PURKINJE NEURONS; CHANNEL BEHAVIOR; CLEAVAGE SITES; CONTROL-CELL; ENDOPLASMIC RETICULUM; FEED-FORWARD; IN-VIVO; INJURY MODELS; INTRACELLULAR CA; INTRACELLULAR STORES; N2A CELLS; SINGLE CHANNEL RECORDING; TRANS-MEMBRANE DOMAINS;

ACTIVATION ANALYSIS; ALCOHOLS; CELL DEATH; CELL MEMBRANES; PHYSIOLOGY; SUGARS;

CALCIUM;

CALCIUM ION; CALPAIN; INOSITOL 1,4,5 TRISPHOSPHATE; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CALCIUM TRANSPORT; CHANNEL GATING; CONTROLLED STUDY; CYTOPLASM; ENDOPLASMIC RETICULUM; HEART ARREST; IN VIVO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PURKINJE CELL; RAT;

ANIMALS; CALCIUM; CALCIUM CHANNELS; CALCIUM IONOPHORES; CALCIUM SIGNALING; CALPAIN; CELL DEATH; CELL LINE; ENDOPLASMIC RETICULUM; HOMEOSTASIS; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS; ION CHANNEL GATING; IONOMYCIN; MALE; PROTEOLYSIS; PURKINJE CELLS; RATS; RATS, LONG-EVANS;

EID: 80053925001     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.254177     Document Type: Article

References (47)

1. Berridge, M. J., Lipp, P., and Bootman, M. D. (2000) Nat. Rev. Mol. Cell Biol. 1, 11-21
2. Orrenius, S., Zhivotovsky, B., and Nicotera, P. (2003) Nat. Rev. Mol. Cell Biol. 4, 552-565
3. Bevers, M. B., and Neumar, R. W. (2008) J. Cereb. Blood Flow Metab. 28, 655-673
4. Jayaraman, T., and Marks, A. R. (1997) Mol. Cell. Biol. 17, 3005-3012
5. Sugawara, H., Kurosaki, M., Takata, M., and Kurosaki, T. (1997) EMBO J. 16, 3078-3088
6. Leissring, M. A., Parker, I., and LaFerla, F. M. (1999) J. Biol. Chem. 274, 32535-32538
7. Leissring, M. A., Paul, B. A., Parker, I., Cotman, C. W., and LaFerla, F. M. (1999) J. Neurochem. 72, 1061-1068
8. Tang, T. S., Tu, H., Chan, E. Y., Maximov, A., Wang, Z., Wellington, C. L., Hayden, M. R., and Bezprozvanny, I. (2003) Neuron 39, 227-239
9. Beresewicz, M., Kowalczyk, J. E., and Zabłocka, B. (2006) Neurochem. Int. 48, 568-571
10. Dahl, C., Haug, L. S., Spilsberg, B., Johansen, J., Ostvold, A. C., and Diemer, N. H. (2000) Neurochem. Int. 36, 379-388
11. Nagasawa, H., and Kogure, K. (1991) Neurosci. Lett. 133, 129-132
12. Nagata, E., Tanaka, K., Suzuki, S., Dembo, T., Fukuuchi, Y., Futatsugi, A., and Mikoshiba, K. (1999) Neuroscience 93, 995-1001
13. Kohno, K., Higuchi, T., Ohta, S., Kohno, K., Kumon, Y., and Sakaki, S. (1997) Neurosci. Lett. 224, 17-20
14. Zaidan, E., and Sims, N. R. (1994) J. Neurochem. 63, 1812-1819
15. Foskett, J. K., White, C., Cheung, K. H., and Mak, D. O. (2007) Physiol. Rev. 87, 593-658
16. Wang, K. K. (2000) Trends Neurosci. 23, 20-26
17. Hirota, J., Furuichi, T., and Mikoshiba, K. (1999) J. Biol. Chem. 274, 34433-34437
18. Diaz, F., and Bourguignon, L. Y. (2000) Cell Calcium 27, 315-328
19. Haug, L. S., Walaas, S. I., and Ostvold, A. C. (2000) J. Neurochem. 75, 1852-1861
20. Assefa, Z., Bultynck, G., Szlufcik, K., Nadif Kasri, N., Vermassen, E., Goris, J., Missiaen, L., Callewaert, G., Parys, J. B., and De Smedt, H. (2004) J. Biol. Chem. 279, 43227-43236
21. Nakayama, T., Hattori, M., Uchida, K., Nakamura, T., Tateishi, Y., Bannai, H., Iwai, M., Michikawa, T., Inoue, T., and Mikoshiba, K. (2004) Biochem. J. 377, 299-307
22. Verbert, L., Lee, B., Kocks, S. L., Assefa, Z., Parys, J. B., Missiaen, L., Callewaert, G., Fissore, R. A., De Smedt, H., and Bultynck, G. (2008) Biol. Cell 100, 39-49
23. Igwe, O. J., and Filla, M. B. (1997) Brain Res. Mol. Brain Res. 46, 39-53
24. Magnusson, A., Haug, L. S., Walaas, S. I., and Ostvold, A. C. (1993) FEBS Lett. 323, 229-232
25. Wojcikiewicz, R. J., and Oberdorf, J. A. (1996) J. Biol. Chem. 271, 16652-16655
26. Joseph, S. K., and Samanta, S. (1993) J. Biol. Chem. 268, 6477-6486
27. Li, C., Wang, X., Vais, H., Thompson, C. B., Foskett, J. K., and White, C. (2007) Proc. Natl. Acad. Sci. U.S.A. 104, 12565-12570
28. Cheung, K. H., Mei, L., Mak, D. O., Hayashi, I., Iwatsubo, T., Kang, D. E., and Foskett, J. K. (2010) Sci. Signal. 3, ra22
29. Cheung, K. H., Shineman, D., Müller, M., Cárdenas, C., Mei, L., Yang, J., Tomita, T., Iwatsubo, T., Lee, V. M., and Foskett, J. K. (2008) Neuron 58, 871-883
30. Ionescu, L., Cheung, K. H., Vais, H., Mak, D. O., White, C., and Foskett, J. K. (2006) J. Physiol. 573, 645-662
31. White, C., Li, C., Yang, J., Petrenko, N. B., Madesh, M., Thompson, C. B., and Foskett, J. K. (2005) Nat. Cell Biol. 7, 1021-1028
32. Che, D., Li, L., Kopil, C. M., Liu, Z., Guo, W., and Neumar, R. W. (2011) Crit. Care Med. 39, 1423-1430
33. Katz, L., Ebmeyer, U., Safar, P., Radovsky, A., and Neumar, R. (1995) J. Cereb. Blood Flow Metab. 15, 1032-1039
34. Neumar, R. W., Bircher, N. G., Sim, K. M., Xiao, F., Zadach, K. S., Radovsky, A., Katz, L., Ebmeyer, E., and Safar, P. (1995) Resuscitation 29, 249-263
35. Colbourne, F., Sutherland, G. R., and Auer, R. N. (1996) J. Neurosci. Methods 67, 185-190
36. Roberts-Lewis, J. M., Savage, M. J., Marcy, V. R., Pinsker, L. R., and Siman, R. (1994) J. Neurosci. 14, 3934-3944
37. Erecińska, M., and Silver, I. A. (1992) Can. J. Physiol. Pharmacol. 70, S190-S193
38. Silver, I. A., and Erecińska, M. (1992) J. Cereb. Blood Flow Metab. 12, 759-772
39. Neumar, R. W. (2000) Ann. Emerg. Med. 36, 483-506
40. Galvan, D. L., Borrego-Diaz, E., Perez, P. J., and Mignery, G. A. (1999) J. Biol. Chem. 274, 29483-29492
41. Sayers, L. G., Miyawaki, A., Muto, A., Takeshita, H., Yamamoto, A., Michikawa, T., Furuichi, T., and Mikoshiba, K. (1997) Biochem. J. 323, 273-280
42. Davis, R. J., Challiss, J., and Nahorski, S. R. (1999) Biochem. J. 341, 813-820
43. Fischer, G. A., Clementi, E., Raichman, M., Südhof, T., Ullrich, A., and Meldolesi, J. (1994) J. Biol. Chem. 269, 19216-19224
44. Mackrill, J. J., Wilcox, R. A., Miyawaki, A., Mikoshiba, K., Nahorski, S. R., and Challiss, R. A. (1996) Biochem. J. 318, 871-878
45. Joseph, S. K., Pierson, S., and Samanta, S. (1995) Biochem. J. 307, 859-865
46. Yoshikawa, F., Iwasaki, H., Michikawa, T., Furuichi, T., and Mikoshiba, K. (1999) J. Biol. Chem. 274, 316-327
47. Foskett, J. K., and Mak, D.-O. D. (2010) in Current Topics in Membranes (Serysheva, I. I., ed) Vol. 66, pp. 235-272, Academic Press, Burlington