-
1
-
-
0031726887
-
Apoptosis: Who was first
-
Degli EM: Apoptosis: Who was first. Cell Death Diff 5:719, 1998
-
(1998)
Cell Death Diff.
, vol.5
, pp. 719
-
-
Degli, E.M.1
-
2
-
-
0015383455
-
Apoptosis: A Basic biological phenomenon with wide-ranging implications in tissue kinetics
-
Kerr JF, Wyllie AH, Currei AR: Apoptosis: a Basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 26:239-257, 1972
-
(1972)
Br. J. Cancer
, vol.26
, pp. 239-257
-
-
Kerr, J.F.1
Wyllie, A.H.2
Currei, A.R.3
-
3
-
-
0025204548
-
Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
-
Hockenberry D, Nunex G, Milliman C, et al: Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 348:334-336, 1990
-
(1990)
Nature
, vol.348
, pp. 334-336
-
-
Hockenberry, D.1
Nunex, G.2
Milliman, C.3
-
4
-
-
9044225527
-
BCL-2 family proteins: Regulators of cell death involved in the pathogenesis of cancer resistance to Therapy
-
Reed JC, Miyashita T, Takayama S, et al: BCL-2 family proteins: Regulators of cell death involved in the pathogenesis of cancer resistance to Therapy. J Cell Biochem 60:23-32, 1996
-
(1996)
J. Cell Biochem.
, vol.60
, pp. 23-32
-
-
Reed, J.C.1
Miyashita, T.2
Takayama, S.3
-
5
-
-
0037050735
-
Upregulation of bcl-2 is involved in the mediation of chemotherapy resistance in human small cell lung cancer cell lines
-
Sartorius UA, Krammer PH: Upregulation of bcl-2 is involved in the mediation of chemotherapy resistance in human small cell lung cancer cell lines. Int J Cancer 97:584-592, 2002
-
(2002)
Int. J. Cancer
, vol.97
, pp. 584-592
-
-
Sartorius, U.A.1
Krammer, P.H.2
-
6
-
-
0031032294
-
Bcl-2 and Bcl-xl antagonize the mitochondrial dysfunction preceding nuclear apoptosis induced by chemotherapeutic agents
-
Decaudin D, Geley S, Hirsch T, et al: Bcl-2 and Bcl-xl antagonize the mitochondrial dysfunction preceding nuclear apoptosis induced by chemotherapeutic agents. Cancer Res 57:62-67, 1997
-
(1997)
Cancer Res.
, vol.57
, pp. 62-67
-
-
Decaudin, D.1
Geley, S.2
Hirsch, T.3
-
7
-
-
0032575688
-
The bcl-2 protein family: Arbiters of cell survival
-
Adams JM, Cory S: The bcl-2 protein family: Arbiters of cell survival. Science 281:1322-1326, 1998
-
(1998)
Science
, vol.281
, pp. 1322-1326
-
-
Adams, J.M.1
Cory, S.2
-
8
-
-
31544483659
-
-
Bethesda, MD, National Cancer Institute
-
Ries LAG, Eisner MP, Kosary CL, et al: SEER Cancer Statistics Review, 1975-2000. Bethesda, MD, National Cancer Institute, 2003
-
(2003)
SEER Cancer Statistics Review, 1975-2000
-
-
Ries, L.A.G.1
Eisner, M.P.2
Kosary, C.L.3
-
9
-
-
0028857747
-
Expression of bcl-2 oncogene protein is prevalent in small cell lung carcinomas
-
Jiang SX, Sato Y, Kuwao S, et al: Expression of bcl-2 oncogene protein is prevalent in small cell lung carcinomas J Pathol 177:135-138, 1995
-
(1995)
J. Pathol.
, vol.177
, pp. 135-138
-
-
Jiang, S.X.1
Sato, Y.2
Kuwao, S.3
-
10
-
-
0029940427
-
Bcl-2 and p53 protein expression in non-small cell lung cancers: Correlation with survival time
-
Ohsaki Y, Toyoshima E, Fujiuchi S, et al: Bcl-2 and p53 protein expression in non-small cell lung cancers: correlation with survival time. Clin Cancer Res 2:915-920, 1996
-
(1996)
Clin. Cancer Res.
, vol.2
, pp. 915-920
-
-
Ohsaki, Y.1
Toyoshima, E.2
Fujiuchi, S.3
-
11
-
-
0027186201
-
bcl-2 protein in non-small cell lung carcinoma
-
Pezzella F, Turley H, Kuzu I, et al: bcl-2 protein in non-small cell lung carcinoma. N Engl J Med 329:690-694, 1993
-
(1993)
N. Engl. J. Med.
, vol.329
, pp. 690-694
-
-
Pezzella, F.1
Turley, H.2
Kuzu, I.3
-
12
-
-
0031049786
-
Bcl-2 oncoprotein in surgically resected nonsmall cell lung cancer: Possibly favorable prognostic factor in association with low incidence of distant metastasis
-
Higashiyama M, Doi O, Kodama K, et al: Bcl-2 oncoprotein in surgically resected nonsmall cell lung cancer: Possibly favorable prognostic factor in association with low incidence of distant metastasis. J Surg Oncol 64:48-54, 1997
-
(1997)
J. Surg. Oncol.
, vol.64
, pp. 48-54
-
-
Higashiyama, M.1
Doi, O.2
Kodama, K.3
-
13
-
-
0035157618
-
Bcl-2 is an independent prognostic factor and adds to a biological model for predicting outcome in operable non-small cell lung cancer
-
Cox G, Jones JL, Andi A, et al: Bcl-2 is an independent prognostic factor and adds to a biological model for predicting outcome in operable non-small cell lung cancer. Lung Cancer 34:417-426, 2001
-
(2001)
Lung Cancer
, vol.34
, pp. 417-426
-
-
Cox, G.1
Jones, J.L.2
Andi, A.3
-
14
-
-
0034100054
-
Predictive survival markers in patients with surgically resected non-small cell lung carcinoma
-
Moldvay J, Scheid P, Wild P, et al: Predictive survival markers in patients with surgically resected non-small cell lung carcinoma. Clin Cancer Res 6:1125-1134, 2000
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 1125-1134
-
-
Moldvay, J.1
Scheid, P.2
Wild, P.3
-
15
-
-
0033031921
-
Expression of apoptosis regulatory proteins of the bcl-2 family and p53 in primary resected non-small-cell lung cancer
-
Borner MM, Brousset P, Pfanner-Meyer B, et al: Expression of apoptosis regulatory proteins of the bcl-2 family and p53 in primary resected non-small-cell lung cancer. Br J Cancer 79:952-958, 1999
-
(1999)
Br. J. Cancer
, vol.79
, pp. 952-958
-
-
Borner, M.M.1
Brousset, P.2
Pfanner-Meyer, B.3
-
16
-
-
0037790894
-
Risk of recurrence in patients with surgically resected stage I non-small cell lung carcinoma
-
Poleri C, Morero JL, Nieva B, et al: Risk of recurrence in patients with surgically resected stage I non-small cell lung carcinoma. Chest 123:1858-1867, 2003
-
(2003)
Chest
, vol.123
, pp. 1858-1867
-
-
Poleri, C.1
Morero, J.L.2
Nieva, B.3
-
17
-
-
17444442088
-
Immunocytochemical markers in stage I lung cancer: Relevance to prognosis
-
Pastorino U, Andreola S, Tagliabue E, et al: Immunocytochemical markers in stage I lung cancer: Relevance to prognosis J Clin Oncol 15:2858-2865, 1997
-
(1997)
J. Clin. Oncol.
, vol.15
, pp. 2858-2865
-
-
Pastorino, U.1
Andreola, S.2
Tagliabue, E.3
-
18
-
-
0038340641
-
Expression of bcl-2 protein is associated with shorter survival in non-small cell lung carcinoma
-
Huang C, Neuberg D, Johnson BE, et al: Expression of bcl-2 protein is associated with shorter survival in non-small cell lung carcinoma. Cancer 98:135-143, 2003
-
(2003)
Cancer
, vol.98
, pp. 135-143
-
-
Huang, C.1
Neuberg, D.2
Johnson, B.E.3
-
19
-
-
0141885988
-
Prognostic significance of bcl-2 expression in resected pN2 non-small cell lung cancer
-
Tomita M, Matsuzaki Y, Edagawa M, et al: Prognostic significance of bcl-2 expression in resected pN2 non-small cell lung cancer. Eur J Surg Oncol 29:654-657, 2003
-
(2003)
Eur. J. Surg. Oncol.
, vol.29
, pp. 654-657
-
-
Tomita, M.1
Matsuzaki, Y.2
Edagawa, M.3
-
20
-
-
0037449786
-
A functional role for nicotine in bcl2 phosphorylation and suppression of apoptosis
-
Mai H, May WS, Gao F, et al: A functional role for nicotine in bcl2 phosphorylation and suppression of apoptosis. J Biol Chem 278:1886-1891, 2003
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 1886-1891
-
-
Mai, H.1
May, W.S.2
Gao, F.3
-
21
-
-
0041343301
-
Role of Bcl-2 as a prognostic factor for survival in lung cancer: A systematic review of the literature with meta-analysis
-
Martin B, Pacsmans M, Berghmans T, et al: Role of Bcl-2 as a prognostic factor for survival in lung cancer: a systematic review of the literature with meta-analysis. Br J Cancer 89:55-64, 2003
-
(2003)
Br. J. Cancer
, vol.89
, pp. 55-64
-
-
Martin, B.1
Pacsmans, M.2
Berghmans, T.3
-
22
-
-
0037312094
-
Bcl-2 and bax expression in advanced non-small cell lung cancer: Lack of correlation with chemotherapy response or survival in patients treated with docetaxel plus vinorelbine
-
Krug LM, Miller VA, Filippa DA, et al: Bcl-2 and bax expression in advanced non-small cell lung cancer: Lack of correlation with chemotherapy response or survival in patients treated with docetaxel plus vinorelbine. Lung Cancer 39:139-143, 2003
-
(2003)
Lung Cancer
, vol.39
, pp. 139-143
-
-
Krug, L.M.1
Miller, V.A.2
Filippa, D.A.3
-
23
-
-
0038676365
-
Measurement of chemoresistance markers in patients with stage III non-small cell lung cancer: A novel approach for patient selection
-
Brooks KR, To K, Joshi MB, et al: Measurement of chemoresistance markers in patients with stage III non-small cell lung cancer: a novel approach for patient selection. Ann Thorac Surg 76:187-193, 2003
-
(2003)
Ann. Thorac. Surg.
, vol.76
, pp. 187-193
-
-
Brooks, K.R.1
To, K.2
Joshi, M.B.3
-
24
-
-
0031471135
-
Potential role of bcl-2 as a suppressor of tumour angiogenesis in non-small-cell lung cancer
-
Koukourakis MI, Giatromanolaki A, O'Byrne KJ, et al: Potential role of bcl-2 as a suppressor of tumour angiogenesis in non-small-cell lung cancer. Int J Cancer 74: 565-570, 1997
-
(1997)
Int. J. Cancer
, vol.74
, pp. 565-570
-
-
Koukourakis, M.I.1
Giatromanolaki, A.2
O'Byrne, K.J.3
-
25
-
-
0033534594
-
Interleukin-3 induces the phsophorylation of a distinct fraction of bcl-2
-
Poommipanit PB, Chen B, Oltvai ZN: Interleukin-3 induces the phsophorylation of a distinct fraction of bcl-2. J Biol Chem 274:1033-1039, 1999
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 1033-1039
-
-
Poommipanit, P.B.1
Chen, B.2
Oltvai, Z.N.3
-
26
-
-
0029943186
-
Expression of apoptosis-regulatory genes in lung tumor cell lines: Relationship to p53 expression and relevance to acquired drug resistance
-
Reeve JG, Xiong J, Morgan J, et al: Expression of apoptosis-regulatory genes in lung tumor cell lines: relationship to p53 expression and relevance to acquired drug resistance. Br J Cancer 73:1193-200, 1996
-
(1996)
Br. J. Cancer
, vol.73
, pp. 1193-1200
-
-
Reeve, J.G.1
Xiong, J.2
Morgan, J.3
-
27
-
-
0032758427
-
Apoptosis and expression of apoptosis regulating proteins bcl-2, mcl-1, bcl-x and bax in malignant mesothelioma
-
Soini Y, Kinnula V, Wiik-Kaarteenaho R, et al: Apoptosis and expression of apoptosis regulating proteins bcl-2, mcl-1, bcl-x and bax in malignant mesothelioma. Clin Can Res 5:3508-3515, 1999
-
(1999)
Clin. Can Res.
, vol.5
, pp. 3508-3515
-
-
Soini, Y.1
Kinnula, V.2
Wiik-Kaarteenaho, R.3
-
28
-
-
0028922885
-
Massive cell death of immature hematopoietic cells and neurons in bcl-xl deficient mice
-
Motoyama N, Wang F, Roth KA, et al: Massive cell death of immature hematopoietic cells and neurons in bcl-xl deficient mice. Science 267:1506-1510, 1995
-
(1995)
Science
, vol.267
, pp. 1506-1510
-
-
Motoyama, N.1
Wang, F.2
Roth, K.A.3
-
29
-
-
0027427492
-
Bcl-2 deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair
-
Veis DJ, Sorenson CM, Shutter JR, et al: Bcl-2 deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair. Cell 75:229-240, 1993
-
(1993)
Cell
, vol.75
, pp. 229-240
-
-
Veis, D.J.1
Sorenson, C.M.2
Shutter, J.R.3
-
30
-
-
0032923254
-
Frequent high expression of bax pro-apoptotic protein in non-small cell lung cancer
-
Caputi M, Groeger AM, Esposito V, et al: Frequent high expression of bax pro-apoptotic protein in non-small cell lung cancer. Anticancer Res 19:825-827, 1999
-
(1999)
Anticancer Res.
, vol.19
, pp. 825-827
-
-
Caputi, M.1
Groeger, A.M.2
Esposito, V.3
-
31
-
-
0030940210
-
Prognostic value of the expression of p53, bcl-2 and bax oncoproteins, and neovascularization in patients with radically resected non-small cell lung cancer
-
Apolinario RM, Van der valk P, De Jong JS, et al: Prognostic value of the expression of p53, bcl-2 and bax oncoproteins, and neovascularization in patients with radically resected non-small cell lung cancer. J Clin Oncol 15:2456-2466, 1997
-
(1997)
J. Clin. Oncol.
, vol.15
, pp. 2456-2466
-
-
Apolinario, R.M.1
Van der valk, P.2
De Jong, J.S.3
-
32
-
-
0036007249
-
Bax and p16INK4A are independent positive prognostic markers for advanced tumour stage of nonsmall cell lung cancer
-
Gessner C, Lieber U, Kuhn H, et al: Bax and p16INK4A are independent positive prognostic markers for advanced tumour stage of nonsmall cell lung cancer. Eur Respir J 19:134-140, 2002
-
(2002)
Eur. Respir. J.
, vol.19
, pp. 134-140
-
-
Gessner, C.1
Lieber, U.2
Kuhn, H.3
-
33
-
-
0041582974
-
Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucledotide
-
Zamecnik PC, Stephenson ML: Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucledotide. Proc Natl Acad Sci USA 75: 280-284, 1978
-
(1978)
Proc. Natl. Acad. Sci. USA
, vol.75
, pp. 280-284
-
-
Zamecnik, P.C.1
Stephenson, M.L.2
-
34
-
-
0033046750
-
Antisense bcl-2 treatment increases programmed cell death in non-small cell lung cancer cell lines
-
Koty PP, Zhang H, Levitt M: Antisense bcl-2 treatment increases programmed cell death in non-small cell lung cancer cell lines. Lung Cancer 23:115-127, 1999
-
(1999)
Lung Cancer
, vol.23
, pp. 115-127
-
-
Koty, P.P.1
Zhang, H.2
Levitt, M.3
-
35
-
-
4243735676
-
Depletion of Bcl-2 by an antisense oligonucleotide induces apoptosis accompanied by oxidation and externalization of phosphatidylserine in NCI-H226 lung carcinoma cells
-
Koty PP, Tyurina YY, Tyurin VA, et al: Depletion of Bcl-2 by an antisense oligonucleotide induces apoptosis accompanied by oxidation and externalization of phosphatidylserine in NCI-H226 lung carcinoma cells. Mol Cell Biochem 234(-235):125-133, 2002
-
(2002)
Mol. Cell Biochem.
, vol.234
, Issue.235
, pp. 125-133
-
-
Koty, P.P.1
Tyurina, Y.Y.2
Tyurin, V.A.3
-
36
-
-
0034684471
-
Chemosensitisation of malignant melanoma by bcl2 antisense therapy
-
Jansen B, Wacheck V, Heere-Ress E, et al: Chemosensitisation of malignant melanoma by bcl2 antisense therapy. Lancet 356:1728-1733, 2000
-
(2000)
Lancet
, vol.356
, pp. 1728-1733
-
-
Jansen, B.1
Wacheck, V.2
Heere-Ress, E.3
-
37
-
-
0031664988
-
Synergistic cytotoxicity of bcl-2 antisense oligodeoxynucleotides and etoposide, doxorubicin and cisplatin on small-cell lung cancer cell lines
-
Zangemeister-Wittke U, Schenker T, Luedke GH, et al: Synergistic cytotoxicity of bcl-2 antisense oligodeoxynucleotides and etoposide, doxorubicin and cisplatin on small-cell lung cancer cell lines. Br J Cancer 78:1035-1042, 1998
-
(1998)
Br. J. Cancer
, vol.78
, pp. 1035-1042
-
-
Zangemeister-Wittke, U.1
Schenker, T.2
Luedke, G.H.3
-
38
-
-
0034071150
-
Induction of apoptosis in lung cancer cells following bcl-xl antisense treatment
-
Leech SH, Olie RA, Gautschi O, et al: Induction of apoptosis in lung cancer cells following bcl-xl antisense treatment. Int J Cancer 86:570-576, 2000
-
(2000)
Int. J. Cancer
, vol.86
, pp. 570-576
-
-
Leech, S.H.1
Olie, R.A.2
Gautschi, O.3
-
39
-
-
0036621573
-
Antisense therapy for malignant mesothelioma with oligonucleotides targeting the bcl-xl gene product
-
Smythe WR, Mohuiddin I, Ozveran M, et al: Antisense therapy for malignant mesothelioma with oligonucleotides targeting the bcl-xl gene product. J Thorac Cardiovasc Surg 123:1191-1198, 2002
-
(2002)
J. Thorac. Cardiovasc. Surg.
, vol.123
, pp. 1191-1198
-
-
Smythe, W.R.1
Mohuiddin, I.2
Ozveran, M.3
-
40
-
-
0003826861
-
Induction of endogenous bcl-xs through the control of bcl-x pre-mRNA splicing by antisense oligonucleotides
-
Taylor JK, Qing QZ, Wyatt JR, et al: Induction of endogenous bcl-xs through the control of bcl-x pre-mRNA splicing by antisense oligonucleotides. Nature Bio 17:1097-1100, 1999
-
(1999)
Nature Bio.
, vol.17
, pp. 1097-1100
-
-
Taylor, J.K.1
Qing, Q.Z.2
Wyatt, J.R.3
-
41
-
-
0034096268
-
A novel bispecific antisense oligonucleotide inhibiting both bcl-2 and bcl-xl expression efficiently induces apoptosis in tumor cells
-
Zangemeister-Wittke U, Leech SH, Olie RA, et al: A novel bispecific antisense oligonucleotide inhibiting both bcl-2 and bcl-xl expression efficiently induces apoptosis in tumor cells. Clin Can Res 6:2547-2555, 2000
-
(2000)
Clin. Can. Res.
, vol.6
, pp. 2547-2555
-
-
Zangemeister-Wittke, U.1
Leech, S.H.2
Olie, R.A.3
-
42
-
-
0035925537
-
Activity of a novel bcl-2/bcl-xl-bispecific antisense oligonucleotide against tumors of diverse histologic origins
-
Gautschi O, Tschopp S, Olie R, et al: Activity of a novel bcl-2/bcl-xl-bispecific antisense oligonucleotide against tumors of diverse histologic origins. J Natl Can Inst 93: 463-471, 2001
-
(2001)
J. Natl. Can. Inst.
, vol.93
, pp. 463-471
-
-
Gautschi, O.1
Tschopp, S.2
Olie, R.3
-
43
-
-
85030885662
-
A bcl-xl antisense adenoviral vector: A novel and effective pro-apoptolic gene therapy construct
-
Boston, MA, June
-
Cao X, Gu J, Miller SD, et al: A bcl-xl antisense adenoviral vector: a novel and effective pro-apoptolic gene therapy construct. 5th Annual Meeting of the American Society of Gene Therapy, Boston, MA, June, 2002
-
(2002)
5th Annual Meeting of the American Society of Gene Therapy
-
-
Cao, X.1
Gu, J.2
Miller, S.D.3
-
44
-
-
0034163805
-
Antitumor effect of adenovirus-mediated Bax gene transfer on p53-sensitive and p53 resistance cancer lines
-
Kagawa S, Gu J, Swisher S, et al: Antitumor effect of adenovirus-mediated Bax gene transfer on p53-sensitive and p53 resistance cancer lines. Cancer Res 60:1157-1161, 2000
-
(2000)
Cancer Res.
, vol.60
, pp. 1157-1161
-
-
Kagawa, S.1
Gu, J.2
Swisher, S.3
-
46
-
-
0036664443
-
Adenovirus-mediated transfer of Bax driven by the vascular endothelial growth factor promoter induces apoptosis in lung cancer cells
-
Kaliberov SA, Buchsbaum DJ, Gillespie GY, et al: Adenovirus-mediated transfer of Bax driven by the vascular endothelial growth factor promoter induces apoptosis in lung cancer cells. Mol Ther 6:190-198, 2002
-
(2002)
Mol. Ther.
, vol.6
, pp. 190-198
-
-
Kaliberov, S.A.1
Buchsbaum, D.J.2
Gillespie, G.Y.3
-
48
-
-
0027166048
-
Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
-
Oltvai ZN, Milliman CL, Korsmeyer SJ: Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74:609-619, 1993
-
(1993)
Cell
, vol.74
, pp. 609-619
-
-
Oltvai, Z.N.1
Milliman, C.L.2
Korsmeyer, S.J.3
-
49
-
-
0037199456
-
Peptides derived from BH3 domains of Bcl-2 family members: A comparative analysis of inhibition of Bcl-2, Bcl-x(L) and Bax oligomerization, induction of cytochrome c release, and activation of cell death
-
Shangary S, Johnson DE: Peptides derived from BH3 domains of Bcl-2 family members: A comparative analysis of inhibition of Bcl-2, Bcl-x(L) and Bax oligomerization, induction of cytochrome c release, and activation of cell death. Biochemistry 4:9485-9495, 2002
-
(2002)
Biochemistry
, vol.4
, pp. 9485-9495
-
-
Shangary, S.1
Johnson, D.E.2
-
50
-
-
0035150803
-
Identification of small-molecule inhibitors of interaction between the BH3 domain and bcl-xl
-
Degterev A, Lugovskoy A, Cardone M, et al: Identification of small-molecule inhibitors of interaction between the BH3 domain and bcl-xl. Nat Cell Biol 3:173-182, 2001
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 173-182
-
-
Degterev, A.1
Lugovskoy, A.2
Cardone, M.3
-
51
-
-
0038217076
-
BH3-domain mimetic compound BH3I-2′ induces rapid damage to the inner mitochondrial membrane prior to the cytochrome c release from mitochondria
-
Feng W, Liu F, Patwari Y, et al: BH3-domain mimetic compound BH3I-2′ induces rapid damage to the inner mitochondrial membrane prior to the cytochrome c release from mitochondria. Brit J Hem 121:332-340, 2003
-
(2003)
Brit. J. Hem.
, vol.121
, pp. 332-340
-
-
Feng, W.1
Liu, F.2
Patwari, Y.3
-
52
-
-
0034691130
-
Structure-based discovery of an organic compound that hinds Bcl-2 protein and induces apoptosis of tumor cells
-
Wang J, Liu D, Zhang Z, et al: Structure-based discovery of an organic compound that hinds Bcl-2 protein and induces apoptosis of tumor cells. Proc Nat Acad Sci 97: 7124-7129, 2000
-
(2000)
Proc. Nat. Acad. Sci.
, vol.97
, pp. 7124-7129
-
-
Wang, J.1
Liu, D.2
Zhang, Z.3
-
53
-
-
2642566181
-
Anti-tumor activity of A-385358: A small molecule inhibitor of Bcl-xl
-
abstr
-
Shoemaker A, Oleksijew A, Qing W, et al: Anti-tumor activity of A-385358: A small molecule inhibitor of Bcl-xl. Proc Am Assoc Can Res 44:1317abstr, 2003
-
(2003)
Proc. Am. Assoc. Can. Res.
, vol.44
, pp. 1317
-
-
Shoemaker, A.1
Oleksijew, A.2
Qing, W.3
-
55
-
-
0036918738
-
Clinical trials of gene therapy for atherosclerotic cardiovascular disease
-
Freedman SB: Clinical trials of gene therapy for atherosclerotic cardiovascular disease. Curr Opin Lipidol 13: 653-661, 2002
-
(2002)
Curr. Opin. Lipidol.
, vol.13
, pp. 653-661
-
-
Freedman, S.B.1
-
56
-
-
0036202847
-
Safety of intravitreous fomivirsen for treatment of cytomegalovirus retinitis in patients with AIDS
-
Vitravene Study Group
-
Vitravene Study Group. Safety of intravitreous fomivirsen for treatment of cytomegalovirus retinitis in patients with AIDS. Am J Opthalmol 133:484-498, 2002
-
(2002)
Am. J. Opthalmol.
, vol.133
, pp. 484-498
-
-
-
57
-
-
0034015672
-
Phase I clinical and pharmacokinetic study of bcl-2 antisense oligonucleotide therapy in patients with non Hodgkin's lymphoma
-
Waters J, Webb A, Cunningham D, et al: Phase I clinical and pharmacokinetic study of bcl-2 antisense oligonucleotide therapy in patients with non Hodgkin's lymphoma. J Clin Oncol 18:1812-1823, 2000
-
(2000)
J. Clin. Oncol.
, vol.18
, pp. 1812-1823
-
-
Waters, J.1
Webb, A.2
Cunningham, D.3
-
58
-
-
0036303535
-
Phase I trial of Bcl-2 antisense oligonucleotide (G3139) administered by continuous intravenous infusion in patients with advanced cancer
-
Morris MJ, Tong WP, Cardo-Cordon C, et al: Phase I trial of Bcl-2 antisense oligonucleotide (G3139) administered by continuous intravenous infusion in patients with advanced cancer. Clin Cancer Res 8:679-683, 2002
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 679-683
-
-
Morris, M.J.1
Tong, W.P.2
Cardo-Cordon, C.3
-
59
-
-
0031907428
-
Bcl-2 antisense therapy chemosensitizes human melanoma in SCID mice
-
Jansen B, Schlagbauer-Wadl H, Brown BD, et al: Bcl-2 antisense therapy chemosensitizes human melanoma in SCID mice. Nat Med 4:232-234, 1998
-
(1998)
Nat. Med.
, vol.4
, pp. 232-234
-
-
Jansen, B.1
Schlagbauer-Wadl, H.2
Brown, B.D.3
-
60
-
-
0034684471
-
Chemosensitisation of malignant melanoma by BCL-2 antisense therapy
-
Jansen B, Wacheck V, Heere-Ress E, et al: Chemosensitisation of malignant melanoma by BCL-2 antisense therapy. Lancet 356:1728-33, 2000
-
(2000)
Lancet
, vol.356
, pp. 1728-1733
-
-
Jansen, B.1
Wacheck, V.2
Heere-Ress, E.3
-
61
-
-
0036236808
-
A pilot trial of G3139, a bcl-2 antisense oligonucleotide, and paclitaxel in patients with chemorefractory small-cell lung cancer
-
Rudin CM, Otterson GA, Mauer AM, et al: A pilot trial of G3139, a bcl-2 antisense oligonucleotide, and paclitaxel in patients with chemorefractory small-cell lung cancer. Ann Oncol 13:539-545, 2002
-
(2002)
Ann. Oncol.
, vol.13
, pp. 539-545
-
-
Rudin, C.M.1
Otterson, G.A.2
Mauer, A.M.3
-
62
-
-
0035678781
-
A Phase I dose finding study of combined treatment with an antisense Bcl-2 oligonucleotide (Genasense) and mitoxantrone in patients with metastatic hormone-refractory prostate cancer
-
Chi KN, Gleave ME, Klasa R, et al: A Phase I dose finding study of combined treatment with an antisense Bcl-2 oligonucleotide (Genasense) and mitoxantrone in patients with metastatic hormone-refractory prostate cancer. Clin Cancer Res 7:3920-3927, 2001
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 3920-3927
-
-
Chi, K.N.1
Gleave, M.E.2
Klasa, R.3
-
63
-
-
0000645010
-
A phase I study of BCL-2 antisense G3139 (GENTA) and weekly docetaxel in patients with advanced breast cancer and other solid tumors
-
(abstr)
-
Chen H, Marshall J, Trocky N, et al: A phase I study of BCL-2 antisense G3139 (GENTA) and weekly docetaxel in patients with advanced breast cancer and other solid tumors. Proc Am Soc Clin Oncol 692, 2000 (abstr)
-
(2000)
Proc. Am. Soc. Clin. Oncol.
, pp. 692
-
-
Chen, H.1
Marshall, J.2
Trocky, N.3
-
64
-
-
0029899181
-
Molecular thanatopsis: A disclosure on the bcl-2 family and cell death
-
Yang E, Korsemeyer SJ: Molecular thanatopsis: a disclosure on the bcl-2 family and cell death. Blood 88:386-401, 1996
-
(1996)
Blood
, vol.88
, pp. 386-401
-
-
Yang, E.1
Korsemeyer, S.J.2
-
65
-
-
12244298187
-
Induction of p53-regulated genes and tumor regression in lung cancer patients after intratumoral delivery of adenoviral p53 (INGN 201) and radiation therapy
-
Swisher SG, Roth JA, Komaki R, et al: Induction of p53-regulated genes and tumor regression in lung cancer patients after intratumoral delivery of adenoviral p53 (INGN 201) and radiation therapy. Clin Cancer Res 9:93-101, 2003
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 93-101
-
-
Swisher, S.G.1
Roth, J.A.2
Komaki, R.3
-
66
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
Elbashir SM, Harborth J, Lendeckel W, et al: Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411:494-498, 2001
-
(2001)
Nature
, vol.411
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
|