메뉴 건너뛰기




Volumn 5, Issue 19, 2006, Pages 2187-2190

ASPP2: A gene that controls life and death in vivo

Author keywords

ASPP2; Haploinsufficient; Knockout mice; p53; Rhabdomyosarcomas; Tumor suppressor

Indexed keywords

BINDING PROTEIN; PROTEIN ASPP2; PROTEIN P53; REGULATOR PROTEIN; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

EID: 33749610878     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.5.19.3266     Document Type: Short Survey
Times cited : (24)

References (32)
  • 1
    • 33644555840 scopus 로고    scopus 로고
    • ASPP [corrected] and cancer
    • Trigiante G, Lu X. ASPP [corrected] and cancer. Nat Rev Cancer 2006; 6:217-26.
    • (2006) Nat Rev Cancer , vol.6 , pp. 217-226
    • Trigiante, G.1    Lu, X.2
  • 4
    • 1342302875 scopus 로고    scopus 로고
    • Hepatitis C virus core protein interacts with p53-binding protein, 53BP2/Bbp/ASPP2, and inhibits p53-mediated apoptosis
    • Cao Y, Hamada T, Matsui T, Date T, Iwabuchi K. Hepatitis C virus core protein interacts with p53-binding protein, 53BP2/Bbp/ASPP2, and inhibits p53-mediated apoptosis. Biochem Biophys Res Commun 2004; 315:788-95.
    • (2004) Biochem Biophys Res Commun , vol.315 , pp. 788-795
    • Cao, Y.1    Hamada, T.2    Matsui, T.3    Date, T.4    Iwabuchi, K.5
  • 5
    • 0038673445 scopus 로고    scopus 로고
    • ASPP2 inhibits APP-BP1-mediated NEDD8 conjugation to cullin-1 and decreases APP-BP1-induced cell proliferation and neuronal apoptosis
    • Chen Y, Liu W, Naumovski L, Neve RL. ASPP2 inhibits APP-BP1-mediated NEDD8 conjugation to cullin-1 and decreases APP-BP1-induced cell proliferation and neuronal apoptosis. J Neurochem 2003; 85:801-9.
    • (2003) J Neurochem , vol.85 , pp. 801-809
    • Chen, Y.1    Liu, W.2    Naumovski, L.3    Neve, R.L.4
  • 6
    • 0035957958 scopus 로고    scopus 로고
    • Yes-associated protein and p53-binding protein-2 interact through their WW and SH3 domains
    • Espanel X, Sudol, M. Yes-associated protein and p53-binding protein-2 interact through their WW and SH3 domains. J Biol Chem 2001; 276:14514-23.
    • (2001) J Biol Chem , vol.276 , pp. 14514-14523
    • Espanel, X.1    Sudol, M.2
  • 7
    • 0033955051 scopus 로고    scopus 로고
    • APCL, a central nervous system-specific homologue of adenomatous polyposis coli tumor suppressor, binds to p53-binding protein 2 and translocates it to the perinucleus
    • Nakagawa H, Koyama K, Murata Y, Morito M, Akiyama T, Nakamura Y. APCL, a central nervous system-specific homologue of adenomatous polyposis coli tumor suppressor, binds to p53-binding protein 2 and translocates it to the perinucleus. Cancer Res 2000; 60:101-5.
    • (2000) Cancer Res , vol.60 , pp. 101-105
    • Nakagawa, H.1    Koyama, K.2    Murata, Y.3    Morito, M.4    Akiyama, T.5    Nakamura, Y.6
  • 8
    • 0033575818 scopus 로고    scopus 로고
    • NF-kappaB subunit p65 binds to 53BP2 and inhibits cell death induced by 53BP2
    • Yang JP, Hori M, Takahashi N, Kawabe T, Kato H, Okamoto T. NF-kappaB subunit p65 binds to 53BP2 and inhibits cell death induced by 53BP2. Oncogene 1999; 18:5177-86.
    • (1999) Oncogene , vol.18 , pp. 5177-5186
    • Yang, J.P.1    Hori, M.2    Takahashi, N.3    Kawabe, T.4    Kato, H.5    Okamoto, T.6
  • 9
    • 0029942921 scopus 로고    scopus 로고
    • The p53-binding protein 53BP2 also interacts with Bc12 and impedes cell cycle progression at G2/M
    • Naumovski L, Cleary ML. The p53-binding protein 53BP2 also interacts with Bc12 and impedes cell cycle progression at G2/M. Mol Cell Biol 1996; 16:3884-92.
    • (1996) Mol Cell Biol , vol.16 , pp. 3884-3892
    • Naumovski, L.1    Cleary, M.L.2
  • 10
    • 0029617851 scopus 로고
    • Protein phosphatase 1 interacts with p53BP2, a protein which binds to the tumor suppressor p53
    • Helps NR, Barker HM, Elledge SJ, Cohen PT. Protein phosphatase 1 interacts with p53BP2, a protein which binds to the tumor suppressor p53. FEBS Lett 1995; 377:295-300.
    • (1995) FEBS Lett , vol.377 , pp. 295-300
    • Helps, N.R.1    Barker, H.M.2    Elledge, S.J.3    Cohen, P.T.4
  • 12
    • 2342461756 scopus 로고    scopus 로고
    • To die or not to die: How does p53 decide?
    • Slee EA, O'Connor DJ, Lu X. To die or not to die: How does p53 decide? Oncogene 2004; 23:2809-18.
    • (2004) Oncogene , vol.23 , pp. 2809-2818
    • Slee, E.A.1    O'Connor, D.J.2    Lu, X.3
  • 13
    • 33646578801 scopus 로고    scopus 로고
    • ASPP2 is a haploinsufficient tumor suppressor that cooperates with p53 to suppress tumor growth
    • Vives, V, Su J, Zhong S, Ratnayaka I, Slee E, Goldin R, Lu X. ASPP2 is a haploinsufficient tumor suppressor that cooperates with p53 to suppress tumor growth. Genes Dev 2006; 20:1262-7.
    • (2006) Genes Dev , vol.20 , pp. 1262-1267
    • Vives, V.1    Su, J.2    Zhong, S.3    Ratnayaka, I.4    Slee, E.5    Goldin, R.6    Lu, X.7
  • 14
    • 0035979691 scopus 로고    scopus 로고
    • A role for thrombin receptor signaling in endothelial cells during embryonic development
    • Griffin CT, Srinivasan Y, Zheng YW, Huang W, Coughlin SR. A role for thrombin receptor signaling in endothelial cells during embryonic development. Science 2001; 293:1666-70.
    • (2001) Science , vol.293 , pp. 1666-1670
    • Griffin, C.T.1    Srinivasan, Y.2    Zheng, Y.W.3    Huang, W.4    Coughlin, S.R.5
  • 15
    • 0035125901 scopus 로고    scopus 로고
    • Synthetic lethality between mutation in Atm and DNA-PK(cs) during murine embryogenesis
    • Gurley KE, Kemp CJ. Synthetic lethality between mutation in Atm and DNA-PK(cs) during murine embryogenesis. Curr Biol 2001; 11:191-4.
    • (2001) Curr Biol , vol.11 , pp. 191-194
    • Gurley, K.E.1    Kemp, C.J.2
  • 21
    • 14844321860 scopus 로고    scopus 로고
    • Downregulated mRNA expression of ASPP and the hypermethylation of the 5′-untranslated region in cancer cell lines retaining wild-type p53
    • Liu ZJ, Lu X, Zhang Y, Zhong S, Gu SZ, Zhang XB, Yang X, Xin HM. Downregulated mRNA expression of ASPP and the hypermethylation of the 5′-untranslated region in cancer cell lines retaining wild-type p53. FEBS Lett 2005; 579:1587-90.
    • (2005) FEBS Lett , vol.579 , pp. 1587-1590
    • Liu, Z.J.1    Lu, X.2    Zhang, Y.3    Zhong, S.4    Gu, S.Z.5    Zhang, X.B.6    Yang, X.7    Xin, H.M.8
  • 22
    • 2542432915 scopus 로고    scopus 로고
    • Haploinsufficiency for tumor suppressor genes: When you don't need to go all the way
    • Santarosa M, Ashworth A. Haploinsufficiency for tumor suppressor genes: When you don't need to go all the way. Biochim Biophys Acta 2004; 1654:105-22.
    • (2004) Biochim Biophys Acta , vol.1654 , pp. 105-122
    • Santarosa, M.1    Ashworth, A.2
  • 23
    • 0032541321 scopus 로고    scopus 로고
    • Retention of wild-type p53 in tumors from p53 heterozygous mice: Reduction of p53 dosage can promote cancer formation
    • Venkatachalam S, Shi YP, Jones SN, Vogel H, Bradley A, Pinkel D, Donehower LA. Retention of wild-type p53 in tumors from p53 heterozygous mice: Reduction of p53 dosage can promote cancer formation. Embo J 1998; 17:4657-67.
    • (1998) Embo J , vol.17 , pp. 4657-4667
    • Venkatachalam, S.1    Shi, Y.P.2    Jones, S.N.3    Vogel, H.4    Bradley, A.5    Pinkel, D.6    Donehower, L.A.7
  • 25
    • 0030575866 scopus 로고    scopus 로고
    • Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2
    • Gorina S, Pavletich NP. Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2. Science 1996; 274:1001-5.
    • (1996) Science , vol.274 , pp. 1001-1005
    • Gorina, S.1    Pavletich, N.P.2
  • 26
    • 0031806708 scopus 로고    scopus 로고
    • Characterization of structural p53 mutants which show selective defects in apoptosis but not cell cycle arrest
    • Ryan KM, Vousden KH. Characterization of structural p53 mutants which show selective defects in apoptosis but not cell cycle arrest. Mol Cell Biol 1998; 18:3692-8.
    • (1998) Mol Cell Biol , vol.18 , pp. 3692-3698
    • Ryan, K.M.1    Vousden, K.H.2
  • 27
    • 0033970863 scopus 로고    scopus 로고
    • Aberrant overexpression of 53BP2 mRNA in lung cancer cell lines
    • Mori T, Okamoto H, Takahashi N, Ueda R, Okamoto T. Aberrant overexpression of 53BP2 mRNA in lung cancer cell lines. FEBS Lett 2000; 465:124-8.
    • (2000) FEBS Lett , vol.465 , pp. 124-128
    • Mori, T.1    Okamoto, H.2    Takahashi, N.3    Ueda, R.4    Okamoto, T.5
  • 28
    • 4344685735 scopus 로고    scopus 로고
    • Methyl-CpG binding protein MBD1 couples histone H3 methylation at lysine 9 by SETDB1 to DNA replication and chromatin assembly
    • Sarraf A, Stancheva I. Methyl-CpG binding protein MBD1 couples histone H3 methylation at lysine 9 by SETDB1 to DNA replication and chromatin assembly. Mol cell 2004; 15:595-605.
    • (2004) Mol Cell , vol.15 , pp. 595-605
    • Sarraf, A.1    Stancheva, I.2
  • 29
    • 1842854235 scopus 로고    scopus 로고
    • Apoptosis stimulating protein of p53 (ASPP2) expression differs in diffuse large B-cell and follicular center lymphoma: Correlation with clinical outcome
    • Lossos IS, Natkunam Y, Levy R, Lopez CD. Apoptosis stimulating protein of p53 (ASPP2) expression differs in diffuse large B-cell and follicular center lymphoma: Correlation with clinical outcome. Leuk Lymphoma 2002; 43:2309-17.
    • (2002) Leuk Lymphoma , vol.43 , pp. 2309-2317
    • Lossos, I.S.1    Natkunam, Y.2    Levy, R.3    Lopez, C.D.4
  • 32
    • 10644278820 scopus 로고    scopus 로고
    • The expression of iASPP in acute leukemias
    • Zhang X, Wang M, Zhou C, Chen S, Wang J. The expression of iASPP in acute leukemias. Leuk Res 2005; 29:179-83.
    • (2005) Leuk Res , vol.29 , pp. 179-183
    • Zhang, X.1    Wang, M.2    Zhou, C.3    Chen, S.4    Wang, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.