-
1
-
-
0037388204
-
Prospective identifcation of tumorigenic breast cancer cells
-
Al-Hajj M, Wicha MS, Benito-Hernandez A, Morrison SJ, Clarke MF. (2003). Prospective identifcation of tumorigenic breast cancer cells. Proc Natl Acad Sci USA, 100, 3983-3988.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 3983-3988
-
-
Al-Hajj, M.1
Wicha, M.S.2
Benito-Hernandez, A.3
Morrison, S.J.4
Clarke, M.F.5
-
2
-
-
30744477450
-
Lymphangiogenesis in development and human disease
-
Alitalo K, Tammela T, Petrova T V. (2005). Lymphangiogenesis in development and human disease. Nature, 438, 946-953.
-
(2005)
Nature
, vol.438
, pp. 946-953
-
-
Alitalo, K.1
Tammela, T.2
Petrova, T.V.3
-
3
-
-
0036781811
-
Ligand-targeted therapeutics in anticancer therapy
-
Allen TM. (2002). Ligand-targeted therapeutics in anticancer therapy. Nat Rev Cancer, 2, 750-763.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 750-763
-
-
Allen, T.M.1
-
4
-
-
0032535999
-
Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model
-
Arap W, Pasqualini R, Ruoslahti E. (1998). Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model. Science, 279, 377-380.
-
(1998)
Science
, vol.279
, pp. 377-380
-
-
Arap, W.1
Pasqualini, R.2
Ruoslahti, E.3
-
5
-
-
78049490200
-
Termal enhancement with optically activated gold nanoshells sensitizes breast cancer stem cells to radiation therapy
-
Atkinson RL, Zhang M, Diagaradjane P, Peddibhotla S, Contreras A, Hilsenbeck SG, Woodward WA, Krishnan S, Chang JC, Rosen JM. (2010). Termal enhancement with optically activated gold nanoshells sensitizes breast cancer stem cells to radiation therapy. Sci Transl Med, 2, 55ra79.
-
(2010)
Sci Transl Med
, vol.2
-
-
Atkinson, R.L.1
Zhang, M.2
Diagaradjane, P.3
Peddibhotla, S.4
Contreras, A.5
Hilsenbeck, S.G.6
Woodward, W.A.7
Krishnan, S.8
Chang, J.C.9
Rosen, J.M.10
-
7
-
-
50349086791
-
A paclitaxel-hyaluronan bioconjugate targeting ovarian cancer afords a potent in vivo therapeutic activity
-
Banzato A, Bobisse S, Rondina M, Renier D, Bettella F, Esposito G, Quintieri L, Meléndez-Alafort L, Mazzi U, Zanovello P, Rosato A. (2008). A paclitaxel-hyaluronan bioconjugate targeting ovarian cancer afords a potent in vivo therapeutic activity. Clin Cancer Res, 14, 3598-3606.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 3598-3606
-
-
Banzato, A.1
Bobisse, S.2
Rondina, M.3
Renier, D.4
Bettella, F.5
Esposito, G.6
Quintieri, L.7
Meléndez-Alafort, L.8
Mazzi, U.9
Zanovello, P.10
Rosato, A.11
-
8
-
-
33845317573
-
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
-
Bao S, Wu Q, McLendon RE, Hao Y, Shi Q, Hjelmeland AB, Dewhirst MW, Bigner DD, Rich JN. (2006). Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature, 444, 756-760.
-
(2006)
Nature
, vol.444
, pp. 756-760
-
-
Bao, S.1
Wu, Q.2
McLendon, R.E.3
Hao, Y.4
Shi, Q.5
Hjelmeland, A.B.6
Dewhirst, M.W.7
Bigner, D.D.8
Rich, J.N.9
-
9
-
-
35348837163
-
Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma
-
Bar EE, Chaudhry A, Lin A, Fan X, Schreck K, Matsui W, Piccirillo S, Vescovi AL, DiMeco F, Olivi A, Eberhart CG. (2007). Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma. Stem Cells, 25, 2524-2533.
-
(2007)
Stem Cells
, vol.25
, pp. 2524-2533
-
-
Bar, E.E.1
Chaudhry, A.2
Lin, A.3
Fan, X.4
Schreck, K.5
Matsui, W.6
Piccirillo, S.7
Vescovi, A.L.8
Dimeco, F.9
Olivi, A.10
Eberhart, C.G.11
-
10
-
-
34848918210
-
Impact of tumor-specifc targeting on the biodistribution and efcacy of siRNA nanoparticles measured by multimodality in vivo imaging
-
Bartlett DW, Su H, Hildebrandt IJ, Weber WA, Davis ME. (2007). Impact of tumor-specifc targeting on the biodistribution and efcacy of siRNA nanoparticles measured by multimodality in vivo imaging. Proc Natl Acad Sci USA, 104, 15549-15554.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 15549-15554
-
-
Bartlett, D.W.1
Su, H.2
Hildebrandt, I.J.3
Weber, W.A.4
Davis, M.E.5
-
11
-
-
81855198905
-
Molecular-targeted nanotherapies in cancer: Enabling treatment specifcity
-
Blanco E, Hsiao A, Ruiz-Esparza GU, Landry MG, Meric-Bernstam F, Ferrari M. (2011). Molecular-targeted nanotherapies in cancer: enabling treatment specifcity. Mol Oncol, 5, 492-503.
-
(2011)
Mol Oncol
, vol.5
, pp. 492-503
-
-
Blanco, E.1
Hsiao, A.2
Ruiz-Esparza, G.U.3
Landry, M.G.4
Meric-Bernstam, F.5
Ferrari, M.6
-
12
-
-
0030789242
-
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
-
Bonnet D, Dick JE. (1997). Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med, 3, 730-737.
-
(1997)
Nat Med
, vol.3
, pp. 730-737
-
-
Bonnet, D.1
Dick, J.E.2
-
13
-
-
84855778719
-
Development and characterization of immuno-nanocarriers targeting the cancer stem cell marker AC133
-
Bourseau-Guilmain E, Béjaud J, Griveau A, Lautram N, Hindré F, Weyland M, Benoit JP, Garcion E. (2012). Development and characterization of immuno-nanocarriers targeting the cancer stem cell marker AC133. Int J Pharm, 423, 93-101.
-
(2012)
Int J Pharm
, vol.423
, pp. 93-101
-
-
Bourseau-Guilmain, E.1
Béjaud, J.2
Griveau, A.3
Lautram, N.4
Hindré, F.5
Weyland, M.6
Benoit, J.P.7
Garcion, E.8
-
14
-
-
25444495269
-
Opinion: Migrating cancer stem cells-an integrated concept of malignant tumour progression
-
Brabletz T, Jung A, Spaderna S, Hlubek F, Kirchner T. (2005). Opinion: migrating cancer stem cells-an integrated concept of malignant tumour progression. Nat Rev Cancer, 5, 744-749.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 744-749
-
-
Brabletz, T.1
Jung, A.2
Spaderna, S.3
Hlubek, F.4
Kirchner, T.5
-
15
-
-
70349826431
-
Understanding the causes of multidrug resistance in cancer: A comparison of doxorubicin and sunitinib
-
Broxterman HJ, Gotink KJ, Verheul HM. (2009). Understanding the causes of multidrug resistance in cancer: a comparison of doxorubicin and sunitinib. Drug Resist Updat, 12, 114-126.
-
(2009)
Drug Resist Updat
, vol.12
, pp. 114-126
-
-
Broxterman, H.J.1
Gotink, K.J.2
Verheul, H.M.3
-
16
-
-
0002740313
-
A quantitative assay for the number of murine lymphoma cells capable of proliferation in vivo
-
Bruce WR, Van Der Gaag H. (1963). A quantitative assay for the number of murine lymphoma cells capable of proliferation in vivo. Nature, 199, 79-80.
-
(1963)
Nature
, vol.199
, pp. 79-80
-
-
Bruce, W.R.1
Van Der Gaag, H.2
-
17
-
-
0036897324
-
Cationic charge determines the distribution of liposomes between the vascular and extravascular compartments of tumors
-
Campbell RB, Fukumura D, Brown EB, Mazzola LM, Izumi Y, Jain RK, Torchilin VP, Munn LL. (2002). Cationic charge determines the distribution of liposomes between the vascular and extravascular compartments of tumors. Cancer Res, 62, 6831-6836.
-
(2002)
Cancer Res
, vol.62
, pp. 6831-6836
-
-
Campbell, R.B.1
Fukumura, D.2
Brown, E.B.3
Mazzola, L.M.4
Izumi, Y.5
Jain, R.K.6
Torchilin, V.P.7
Munn, L.L.8
-
19
-
-
0036674501
-
Dissemination and growth of cancer cells in metastatic sites
-
Chambers AF, Groom AC, MacDonald IC. (2002). Dissemination and growth of cancer cells in metastatic sites. Nat Rev Cancer, 2, 563-572.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 563-572
-
-
Chambers, A.F.1
Groom, A.C.2
MacDonald, I.C.3
-
20
-
-
78549294156
-
Multifunctional tumor-targeted polymer-peptide-drug delivery system for treatment of primary and metastatic cancers
-
Chandna P, Khandare JJ, Ber E, Rodriguez-Rodriguez L, Minko T. (2010). Multifunctional tumor-targeted polymer-peptide-drug delivery system for treatment of primary and metastatic cancers. Pharm Res, 27, 2296-2306.
-
(2010)
Pharm Res
, vol.27
, pp. 2296-2306
-
-
Chandna, P.1
Khandare, J.J.2
Ber, E.3
Rodriguez-Rodriguez, L.4
Minko, T.5
-
21
-
-
40949127319
-
Terapeutic nanoparticles for drug delivery in cancer
-
Cho K, Wang X, Nie S, Chen ZG, Shin DM. (2008). Terapeutic nanoparticles for drug delivery in cancer. Clin Cancer Res, 14, 1310-1316.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 1310-1316
-
-
Cho, K.1
Wang, X.2
Nie, S.3
Chen, Z.G.4
Shin, D.M.5
-
22
-
-
70350335729
-
Self-assembled hyaluronic acid nanoparticles for active tumor targeting
-
Choi KY, Chung H, Min KH, Yoon HY, Kim K, Park JH, Kwon IC, Jeong SY. (2010). Self-assembled hyaluronic acid nanoparticles for active tumor targeting. Biomaterials, 31, 106-114.
-
(2010)
Biomaterials
, vol.31
, pp. 106-114
-
-
Choi, K.Y.1
Chung, H.2
Min, K.H.3
Yoon, H.Y.4
Kim, K.5
Park, J.H.6
Kwon, I.C.7
Jeong, S.Y.8
-
23
-
-
33645693408
-
Intraperitoneal immunotherapy for metastatic ovarian carcinoma: Resistance of intratumoral collagen to antibody penetration
-
Choi J, Credit K, Henderson K, Deverkadra R, He Z, Wiig H, Vanpelt H, Flessner MF. (2006). Intraperitoneal immunotherapy for metastatic ovarian carcinoma: Resistance of intratumoral collagen to antibody penetration. Clin Cancer Res, 12, 1906-1912.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 1906-1912
-
-
Choi, J.1
Credit, K.2
Henderson, K.3
Deverkadra, R.4
He, Z.5
Wiig, H.6
Vanpelt, H.7
Flessner, M.F.8
-
24
-
-
33646720082
-
Sublethal irradiation induces vascular endothelial growth factor and promotes growth of hepatoma cells: Implications for radiotherapy of hepatocellular carcinoma
-
Chung YL, Jian JJ, Cheng SH, Tsai SY, Chuang V P, Soong T, Lin YM, Horng C F. (2006). Sublethal irradiation induces vascular endothelial growth factor and promotes growth of hepatoma cells: implications for radiotherapy of hepatocellular carcinoma. Clin Cancer Res, 12, 2706-2715.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 2706-2715
-
-
Chung, Y.L.1
Jian, J.J.2
Cheng, S.H.3
Tsai, S.Y.4
Chuang, V.P.5
Soong, T.6
Lin, Y.M.7
Horng, C.F.8
-
25
-
-
77957259799
-
N-(2-Hydroxypropyl) methacrylamide-based polymer conjugates with pH-controlled activation of doxorubicin for cell-specifc or passive tumour targeting. Synthesis by RAFT polymerisation and physicochemical characterisation
-
Chytil P, Etrych T, Kríž J, Šubr V, Ulbrich K. (2010). N-(2-Hydroxypropyl) methacrylamide-based polymer conjugates with pH-controlled activation of doxorubicin for cell-specifc or passive tumour targeting. Synthesis by RAFT polymerisation and physicochemical characterisation. Eur J Pharm Sci, 41, 473-482.
-
(2010)
Eur J Pharm Sci
, vol.41
, pp. 473-482
-
-
Chytil, P.1
Etrych, T.2
Kríž, J.3
Šubr, V.4
Ulbrich, K.5
-
26
-
-
79952370202
-
The cancer stem cell: Premises, promises and challenges
-
Clevers H. (2011). The cancer stem cell: premises, promises and challenges. Nat Med, 17, 313-319.
-
(2011)
Nat Med
, vol.17
, pp. 313-319
-
-
Clevers, H.1
-
27
-
-
76449108068
-
Prostate cancer: Regeneration of interest in the prostate
-
Collins AT, Maitland NJ. (2009). Prostate cancer: regeneration of interest in the prostate. Nat Rev Urol, 6, 184-186.
-
(2009)
Nat Rev Urol
, vol.6
, pp. 184-186
-
-
Collins, A.T.1
Maitland, N.J.2
-
28
-
-
33751106653
-
New approaches to molecular cancer therapeutics
-
Collins I, Workman P. (2006). New approaches to molecular cancer therapeutics. Nat Chem Biol, 2, 689-700.
-
(2006)
Nat Chem Biol
, vol.2
, pp. 689-700
-
-
Collins, I.1
Workman, P.2
-
29
-
-
77953687871
-
HER2 targeting as a two-sided strategy for breast cancer diagnosis and treatment: Outlook and recent implications in nanomedical approaches
-
Colombo M, Corsi F, Foschi D, Mazzantini E, Mazzucchelli S, Morasso C, Occhipinti E, Polito L, Prosperi D, Ronchi S, Verderio P. (2010). HER2 targeting as a two-sided strategy for breast cancer diagnosis and treatment: Outlook and recent implications in nanomedical approaches. Pharmacol Res, 62, 150-165.
-
(2010)
Pharmacol Res
, vol.62
, pp. 150-165
-
-
Colombo, M.1
Corsi, F.2
Foschi, D.3
Mazzantini, E.4
Mazzucchelli, S.5
Morasso, C.6
Occhipinti, E.7
Polito, L.8
Prosperi, D.9
Ronchi, S.10
Verderio, P.11
-
30
-
-
0035206993
-
Enhanced biorecognition and internalization of HPMA copolymers containing multiple or multivalent carbohydrate side-chains by human hepatocarcinoma cells
-
David A, Kopecková P, Rubinstein A, Kopecek J. (2001). Enhanced biorecognition and internalization of HPMA copolymers containing multiple or multivalent carbohydrate side-chains by human hepatocarcinoma cells. Bioconjug Chem, 12, 890-899.
-
(2001)
Bioconjug Chem
, vol.12
, pp. 890-899
-
-
David, A.1
Kopecková, P.2
Rubinstein, A.3
Kopecek, J.4
-
31
-
-
1642453836
-
Radiation improves the distribution and uptake of liposomal doxorubicin (caelyx) in human osteosarcoma xenografts
-
Davies C de L, Lundstrøm LM, Frengen J, Eikenes L, Burland ØS, Kaalhus O, Hjelstuen MH, Brekken C. (2004). Radiation improves the distribution and uptake of liposomal doxorubicin (caelyx) in human osteosarcoma xenografts. Cancer Res, 64, 547-553.
-
(2004)
Cancer Res
, vol.64
, pp. 547-553
-
-
Davies, C.D.L.1
Lundstrøm, L.M.2
Frengen, J.3
Eikenes, L.4
Burland, Ø.S.5
Kaalhus, O.6
Hjelstuen, M.H.7
Brekken, C.8
-
32
-
-
67249128859
-
The frst targeted delivery of siRNA in humans via a self-assembling, cyclodextrin polymer-based nanoparticle: From concept to clinic
-
Davis ME. (2009). The frst targeted delivery of siRNA in humans via a self-assembling, cyclodextrin polymer-based nanoparticle: from concept to clinic. Mol Pharm, 6, 659-668.
-
(2009)
Mol Pharm
, vol.6
, pp. 659-668
-
-
Davis, M.E.1
-
33
-
-
16844368698
-
Tumour stem cells and drug resistance
-
Dean M, Fojo T, Bates S. (2005). Tumour stem cells and drug resistance. Nat Rev Cancer, 5, 275-284.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 275-284
-
-
Dean, M.1
Fojo, T.2
Bates, S.3
-
34
-
-
58149380742
-
Stem cell concepts renew cancer research
-
Dick JE. (2008). Stem cell concepts renew cancer research. Blood, 112, 4793-4807.
-
(2008)
Blood
, vol.112
, pp. 4793-4807
-
-
Dick, J.E.1
-
35
-
-
60149109533
-
Looking ahead in cancer stem cell research
-
Dick JE. (2009). Looking ahead in cancer stem cell research. Nat Biotechnol, 27, 44-46.
-
(2009)
Nat Biotechnol
, vol.27
, pp. 44-46
-
-
Dick, J.E.1
-
36
-
-
81855170441
-
Nanomedicine(s) under the microscope
-
Duncan R, Gaspar R. (2011). Nanomedicine(s) under the microscope. Mol Pharm, 8, 2101-2141.
-
(2011)
Mol Pharm
, vol.8
, pp. 2101-2141
-
-
Duncan, R.1
Gaspar, R.2
-
37
-
-
0041461026
-
High-molecular weight HPMA copolymer-adriamycin conjugates
-
Dvorák M, Kopecková P, Kopecek J. (1999). High-molecular weight HPMA copolymer-adriamycin conjugates. J Control Release, 60, 321-332.
-
(1999)
J Control Release
, vol.60
, pp. 321-332
-
-
Dvorák, M.1
Kopecková, P.2
Kopecek, J.3
-
38
-
-
6344250414
-
Modulation of prostate cancer growth in bone microenvironments
-
Edlund M, Sung SY, Chung LW. (2004). Modulation of prostate cancer growth in bone microenvironments. J Cell Biochem, 91, 686-705.
-
(2004)
J Cell Biochem
, vol.91
, pp. 686-705
-
-
Edlund, M.1
Sung, S.Y.2
Chung, L.W.3
-
40
-
-
63549094211
-
Tumor-targeted nanomedicines: Enhanced antitumor efcacy in vivo of doxorubicin-loaded, long-circulating liposomes modifed with cancer-specifc monoclonal antibody
-
ElBayoumi TA, Torchilin VP. (2009). Tumor-targeted nanomedicines: enhanced antitumor efcacy in vivo of doxorubicin-loaded, long-circulating liposomes modifed with cancer-specifc monoclonal antibody. Clin Cancer Res, 15, 1973-1980.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 1973-1980
-
-
Elbayoumi, T.A.1
Torchilin, V.P.2
-
41
-
-
57049169207
-
Conjugates of doxorubicin with graft HPMA copolymers for passive tumor targeting
-
Etrych T, Chytil P, Mrkvan T, Šírová M, Ríhová B, Ulbrich K. (2008). Conjugates of doxorubicin with graft HPMA copolymers for passive tumor targeting. J Control Release, 132, 184-192.
-
(2008)
J Control Release
, vol.132
, pp. 184-192
-
-
Etrych, T.1
Chytil, P.2
Mrkvan, T.3
Šírová, M.4
Ríhová, B.5
Ulbrich, K.6
-
42
-
-
84870252834
-
HPMA copolymer-doxorubicin conjugates: The efects of molecular weight and architecture on biodistribution and in vivo activity
-
DOI: 10.1016/j.jconrel.2012.06.029
-
Etrych T, Šubr V, Strohalm J, Šírová M, Ríhová B, Ulbrich K. (2012). HPMA copolymer-doxorubicin conjugates: The efects of molecular weight and architecture on biodistribution and in vivo activity. J Control Release, DOI: 10.1016/j.jconrel.2012.06.029.
-
(2012)
J Control Release
-
-
Etrych, T.1
Šubr, V.2
Strohalm, J.3
Šírová, M.4
Ríhová, B.5
Ulbrich, K.6
-
43
-
-
79953054576
-
The EPR efect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the efect
-
Fang J, Nakamura H, Maeda H. (2011). The EPR efect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the efect. Adv Drug Deliv Rev, 63, 136-151.
-
(2011)
Adv Drug Deliv Rev
, vol.63
, pp. 136-151
-
-
Fang, J.1
Nakamura, H.2
Maeda, H.3
-
44
-
-
0037508920
-
Factors and mechanism of "ePR" efect and the enhanced antitumor efects of macromolecular drugs including SMANCS
-
Fang J, Sawa T, Maeda H. (2003). Factors and mechanism of "EPR" efect and the enhanced antitumor efects of macromolecular drugs including SMANCS. Adv Exp Med Biol, 519, 29-49.
-
(2003)
Adv Exp Med Biol
, vol.519
, pp. 29-49
-
-
Fang, J.1
Sawa, T.2
Maeda, H.3
-
45
-
-
0021674404
-
Sites of recurrence in resected stage i non-small-cell lung cancer: A guide for future studies
-
Feld R, Rubinstein LV, Weisenberger TH. (1984). Sites of recurrence in resected stage I non-small-cell lung cancer: a guide for future studies. J Clin Oncol, 2, 1352-1358.
-
(1984)
J Clin Oncol
, vol.2
, pp. 1352-1358
-
-
Feld, R.1
Rubinstein, L.V.2
Weisenberger, T.H.3
-
46
-
-
0028929803
-
Angiogenesis in cancer, vascular, rheumatoid and other disease
-
Folkman J. (1995). Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat Med, 1, 27-31.
-
(1995)
Nat Med
, vol.1
, pp. 27-31
-
-
Folkman, J.1
-
47
-
-
81855169565
-
Cancer invasion and the microenvironment: Plasticity and reciprocity
-
Friedl P, Alexander S. (2011). Cancer invasion and the microenvironment: plasticity and reciprocity. Cell, 147, 992-1009.
-
(2011)
Cell
, vol.147
, pp. 992-1009
-
-
Friedl, P.1
Alexander, S.2
-
48
-
-
84965820581
-
The transmission of leukemia of mice with a single cell
-
Furth J, Kahn M. (1937). The transmission of leukemia of mice with a single cell. Am J Cancer, 31, 276-282.
-
(1937)
Am J Cancer
, vol.31
, pp. 276-282
-
-
Furth, J.1
Kahn, M.2
-
49
-
-
0346333236
-
In vivo fate of folate-targeted polyethylene-glycol liposomes in tumor-bearing mice
-
Gabizon A, Horowitz AT, Goren D, Tzemach D, Shmeeda H, Zalipsky S. (2003). In vivo fate of folate-targeted polyethylene-glycol liposomes in tumor-bearing mice. Clin Cancer Res, 9, 6551-6559.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 6551-6559
-
-
Gabizon, A.1
Horowitz, A.T.2
Goren, D.3
Tzemach, D.4
Shmeeda, H.5
Zalipsky, S.6
-
50
-
-
66049102512
-
Hedgehog signaling is dispensable for adult hematopoietic stem cell function
-
Gao J, Graves S, Koch U, Liu S, Jankovic V, Buonamici S, El Andaloussi A, Nimer SD, Kee BL, Taichman R, Radtke F, Aifantis I. (2009). Hedgehog signaling is dispensable for adult hematopoietic stem cell function. Cell Stem Cell, 4, 548-558.
-
(2009)
Cell Stem Cell
, vol.4
, pp. 548-558
-
-
Gao, J.1
Graves, S.2
Koch, U.3
Liu, S.4
Jankovic, V.5
Buonamici, S.6
El Andaloussi, A.7
Nimer, S.D.8
Kee, B.L.9
Taichman, R.10
Radtke, F.11
Aifantis, I.12
-
51
-
-
74449085757
-
Lyophilized HER2-specifc PEGylated immunoliposomes for active siRNA gene silencing
-
Gao J, Sun J, Li H, Liu W, Zhang Y, Li B, Qian W, Wang H, Chen J, Guo Y. (2010). Lyophilized HER2-specifc PEGylated immunoliposomes for active siRNA gene silencing. Biomaterials, 31, 2655-2664.
-
(2010)
Biomaterials
, vol.31
, pp. 2655-2664
-
-
Gao, J.1
Sun, J.2
Li, H.3
Liu, W.4
Zhang, Y.5
Li, B.6
Qian, W.7
Wang, H.8
Chen, J.9
Guo, Y.10
-
52
-
-
29244439607
-
Colon-specifc 9-aminocamptothecin-HPMA copolymer conjugates containing a 1, 6-elimination spacer
-
Gao SQ, Lu ZR, Petri B, Kopecková P, Kopecek J. (2006). Colon-specifc 9-aminocamptothecin-HPMA copolymer conjugates containing a 1, 6-elimination spacer. J Control Release, 110, 323-331.
-
(2006)
J Control Release
, vol.110
, pp. 323-331
-
-
Gao, S.Q.1
Lu, Z.R.2
Petri, B.3
Kopecková, P.4
Kopecek, J.5
-
53
-
-
33846536256
-
Biodistribution and pharmacokinetics of colon-specifc HPMA copolymer-9-aminocamptothecin conjugate in mice
-
Gao SQ, Lu ZR, Kopecková P, Kopecek J. (2007). Biodistribution and pharmacokinetics of colon-specifc HPMA copolymer-9-aminocamptothecin conjugate in mice. J Control Release, 117, 179-185.
-
(2007)
J Control Release
, vol.117
, pp. 179-185
-
-
Gao, S.Q.1
Lu, Z.R.2
Kopecková, P.3
Kopecek, J.4
-
54
-
-
38049165649
-
Pharmacokinetic modeling of absorption behavior of 9-aminocamptothecin (9-AC) released from colon-specifc HPMA copolymer-9-AC conjugate in rats
-
Gao SQ, Sun Y, Kopecková P, Peterson CM, Kopecek J. (2008). Pharmacokinetic modeling of absorption behavior of 9-aminocamptothecin (9-AC) released from colon-specifc HPMA copolymer-9-AC conjugate in rats. Pharm Res, 25, 218-226.
-
(2008)
Pharm Res
, vol.25
, pp. 218-226
-
-
Gao, S.Q.1
Sun, Y.2
Kopecková, P.3
Peterson, C.M.4
Kopecek, J.5
-
55
-
-
70449686361
-
Antitumor efcacy of colon-specifc HPMA copolymer/9-aminocamptothecin conjugates in mice bearing human-colon carcinoma xenografts
-
Gao SQ, Sun Y, Kopecková P, Peterson CM, Kopecek J. (2009). Antitumor efcacy of colon-specifc HPMA copolymer/9-aminocamptothecin conjugates in mice bearing human-colon carcinoma xenografts. Macromol Biosci, 9, 1135-1142.
-
(2009)
Macromol Biosci
, vol.9
, pp. 1135-1142
-
-
Gao, S.Q.1
Sun, Y.2
Kopecková, P.3
Peterson, C.M.4
Kopecek, J.5
-
56
-
-
9444258072
-
Randomized phase III trial of liposomal daunorubicin versus doxorubicin, bleomycin, and vincristine in AIDS-related Kaposi's sarcoma
-
Gill PS, Wernz J, Scadden DT, Cohen P, Mukwaya GM, von Roenn JH, Jacobs M, Kempin S, Silverberg I, Gonzales G, Rarick MU, Myers AM, Shepherd F, Sawka C, Pike MC, Ross ME. (1996). Randomized phase III trial of liposomal daunorubicin versus doxorubicin, bleomycin, and vincristine in AIDS-related Kaposi's sarcoma. J Clin Oncol, 14, 2353-2364.
-
(1996)
J Clin Oncol
, vol.14
, pp. 2353-2364
-
-
Gill, P.S.1
Wernz, J.2
Scadden, D.T.3
Cohen, P.4
Mukwaya, G.M.5
Von Roenn, J.H.6
Jacobs, M.7
Kempin, S.8
Silverberg, I.9
Gonzales, G.10
Rarick, M.U.11
Myers, A.M.12
Shepherd, F.13
Sawka, C.14
Pike, M.C.15
Ross, M.E.16
-
57
-
-
33845864778
-
Complete inhibition of P-glycoprotein by simultaneous treatment with a distinct class of modulators and the UIC2 monoclonal antibody
-
Goda K, Fenyvesi F, Bacsó Z, Nagy H, Márián T, Megyeri A, Krasznai Z, Juhász I, Vecsernyés M, Szabó G Jr. (2007). Complete inhibition of P-glycoprotein by simultaneous treatment with a distinct class of modulators and the UIC2 monoclonal antibody. J Pharmacol Exp Ter, 320, 81-88.
-
(2007)
J Pharmacol Exp ter
, vol.320
, pp. 81-88
-
-
Goda, K.1
Fenyvesi, F.2
Bacsó, Z.3
Nagy, H.4
Márián, T.5
Megyeri, A.6
Krasznai, Z.7
Juhász, I.8
Vecsernyés, M.9
Szabó Jr. G10
-
58
-
-
0035879099
-
Recurrent epithelial ovarian carcinoma: A randomized phase III study of pegylated liposomal doxorubicin versus topotecan
-
Gordon AN, Fleagle JT, Guthrie D, Parkin DE, Gore ME, Lacave AJ. (2001). Recurrent epithelial ovarian carcinoma: a randomized phase III study of pegylated liposomal doxorubicin versus topotecan. J Clin Oncol, 19, 3312-3322.
-
(2001)
J Clin Oncol
, vol.19
, pp. 3312-3322
-
-
Gordon, A.N.1
Fleagle, J.T.2
Guthrie, D.3
Parkin, D.E.4
Gore, M.E.5
Lacave, A.J.6
-
59
-
-
32944482677
-
Phase III trial of nanoparticle albumin-bound paclitaxel compared with polyethylated castor oil-based paclitaxel in women with breast cancer
-
Gradishar WJ, Tjulandin S, Davidson N, Shaw H, Desai N, Bhar P, Hawkins M, O'Shaughnessy J. (2005). Phase III trial of nanoparticle albumin-bound paclitaxel compared with polyethylated castor oil-based paclitaxel in women with breast cancer. J Clin Oncol, 23, 7794-7803.
-
(2005)
J Clin Oncol
, vol.23
, pp. 7794-7803
-
-
Gradishar, W.J.1
Tjulandin, S.2
Davidson, N.3
Shaw, H.4
Desai, N.5
Bhar, P.6
Hawkins, M.7
O'Shaughnessy, J.8
-
60
-
-
33846549188
-
Investigating the mechanism of enhanced cytotoxicity of HPMA copolymer-Dox-AGM in breast cancer cells
-
Greco F, Vicent MJ, Gee S, Jones AT, Gee J, Nicholson RI, Duncan R. (2007). Investigating the mechanism of enhanced cytotoxicity of HPMA copolymer-Dox-AGM in breast cancer cells. J Control Release, 117, 28-39.
-
(2007)
J Control Release
, vol.117
, pp. 28-39
-
-
Greco, F.1
Vicent, M.J.2
Gee, S.3
Jones, A.T.4
Gee, J.5
Nicholson, R.I.6
Duncan, R.7
-
61
-
-
68749099671
-
Identifcation of selective inhibitors of cancer stem cells by high-throughput screening
-
Gupta PB, Onder TT, Jiang G, Tao K, Kuperwasser C, Weinberg RA, Lander ES. (2009). Identifcation of selective inhibitors of cancer stem cells by high-throughput screening. Cell, 138, 645-659.
-
(2009)
Cell
, vol.138
, pp. 645-659
-
-
Gupta, P.B.1
Onder, T.T.2
Jiang, G.3
Tao, K.4
Kuperwasser, C.5
Weinberg, R.A.6
Lander, E.S.7
-
62
-
-
80051967505
-
Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells
-
Gupta PB, Fillmore CM, Jiang G, Shapira SD, Tao K, Kuperwasser C, Lander ES. (2011). Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells. Cell, 146, 633-644.
-
(2011)
Cell
, vol.146
, pp. 633-644
-
-
Gupta, P.B.1
Fillmore, C.M.2
Jiang, G.3
Shapira, S.D.4
Tao, K.5
Kuperwasser, C.6
Lander, E.S.7
-
63
-
-
84858590826
-
Accessories to the crime: Functions of cells recruited to the tumor microenvironment
-
Hanahan D, Coussens LM. (2012). Accessories to the crime: functions of cells recruited to the tumor microenvironment. Cancer Cell, 21, 309-322.
-
(2012)
Cancer Cell
, vol.21
, pp. 309-322
-
-
Hanahan, D.1
Coussens, L.M.2
-
64
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA. (2000). The hallmarks of cancer. Cell, 100, 57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
65
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan D, Weinberg RA. (2011). Hallmarks of cancer: the next generation. Cell, 144, 646-674.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
66
-
-
0038469746
-
Noninvasive detection of clinically occult lymph-node metastases in prostate cancer
-
Harisinghani MG, Barentsz J, Hahn PF, Deserno WM, Tabatabaei S, van de Kaa CH, de la Rosette J, Weissleder R. (2003). Noninvasive detection of clinically occult lymph-node metastases in prostate cancer. N Engl J Med, 348, 2491-2499.
-
(2003)
N Engl J Med
, vol.348
, pp. 2491-2499
-
-
Harisinghani, M.G.1
Barentsz, J.2
Hahn, P.F.3
Deserno, W.M.4
Tabatabaei, S.5
Van De Kaa, C.H.6
De La Rosette, J.7
Weissleder, R.8
-
67
-
-
0033839080
-
Openings between defective endothelial cells explain tumor vessel leakiness
-
Hashizume H, Baluk P, Morikawa S, McLean JW, Turston G, Roberge S, Jain RK, McDonald DM. (2000). Openings between defective endothelial cells explain tumor vessel leakiness. Am J Pathol, 156, 1363-1380.
-
(2000)
Am J Pathol
, vol.156
, pp. 1363-1380
-
-
Hashizume, H.1
Baluk, P.2
Morikawa, S.3
McLean, J.W.4
Turston, G.5
Roberge, S.6
Jain, R.K.7
McDonald, D.M.8
-
68
-
-
79952487130
-
Clinical developments in nanotechnology for cancer therapy
-
Heidel JD, Davis ME. (2011). Clinical developments in nanotechnology for cancer therapy. Pharm Res, 28, 187-199.
-
(2011)
Pharm Res
, vol.28
, pp. 187-199
-
-
Heidel, J.D.1
Davis, M.E.2
-
69
-
-
4944266313
-
High interstitial fuid pressure-an obstacle in cancer therapy
-
Heldin CH, Rubin K, Pietras K, Ostman A. (2004). High interstitial fuid pressure-an obstacle in cancer therapy. Nat Rev Cancer, 4, 806-813.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 806-813
-
-
Heldin, C.H.1
Rubin, K.2
Pietras, K.3
Ostman, A.4
-
70
-
-
33645834966
-
Metastatic patterns in adenocarcinoma
-
Hess KR, Varadhachary GR, Taylor SH, Wei W, Raber MN, Lenzi R, Abbruzzese JL. (2006). Metastatic patterns in adenocarcinoma. Cancer, 106, 1624-1633.
-
(2006)
Cancer
, vol.106
, pp. 1624-1633
-
-
Hess, K.R.1
Varadhachary, G.R.2
Taylor, S.H.3
Wei, W.4
Raber, M.N.5
Lenzi, R.6
Abbruzzese, J.L.7
-
71
-
-
4644306516
-
A distinct "side population" of cells with high drug efux capacity in human tumor cells
-
Hirschmann-Jax C, Foster AE, Wulf GG, Nuchtern JG, Jax TW, Gobel U, Goodell MA, Brenner MK. (2004). A distinct "side population" of cells with high drug efux capacity in human tumor cells. Proc Natl Acad Sci USA, 101, 14228-14233.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 14228-14233
-
-
Hirschmann-Jax, C.1
Foster, A.E.2
Wulf, G.G.3
Nuchtern, J.G.4
Jax, T.W.5
Gobel, U.6
Goodell, M.A.7
Brenner, M.K.8
-
72
-
-
66049085125
-
Hedgehog signaling is dispensable for adult murine hematopoietic stem cell function and hematopoiesis
-
Hofmann I, Stover EH, Cullen DE, Mao J, Morgan KJ, Lee BH, Kharas MG, Miller PG, Cornejo MG, Okabe R, Armstrong SA, Ghilardi N, Gould S, de Sauvage FJ, McMahon AP, Gilliland DG. (2009). Hedgehog signaling is dispensable for adult murine hematopoietic stem cell function and hematopoiesis. Cell Stem Cell, 4, 559-567.
-
(2009)
Cell Stem Cell
, vol.4
, pp. 559-567
-
-
Hofmann, I.1
Stover, E.H.2
Cullen, D.E.3
Mao, J.4
Morgan, K.J.5
Lee, B.H.6
Kharas, M.G.7
Miller, P.G.8
Cornejo, M.G.9
Okabe, R.10
Armstrong, S.A.11
Ghilardi, N.12
Gould, S.13
De Sauvage, F.J.14
McMahon, A.P.15
Gilliland, D.G.16
-
73
-
-
56049117207
-
Combination chemotherapy and photodynamic therapy with fab' fragment targeted HPMA copolymer conjugates in human ovarian carcinoma cells
-
Hongrapipat J, Kopecková P, Liu J, Prakongpan S, Kopecek J. (2008a). Combination chemotherapy and photodynamic therapy with fab' fragment targeted HPMA copolymer conjugates in human ovarian carcinoma cells. Mol Pharm, 5, 696-709.
-
(2008)
Mol Pharm
, vol.5
, pp. 696-709
-
-
Hongrapipat, J.1
Kopecková, P.2
Liu, J.3
Prakongpan, S.4
Kopecek, J.5
-
74
-
-
38749144812
-
Enhanced antitumor activity of combinations of free and HPMA copolymer-bound drugs
-
Hongrapipat J, Kopecková P, Prakongpan S, Kopecek J. (2008b). Enhanced antitumor activity of combinations of free and HPMA copolymer-bound drugs. Int J Pharm, 351, 259-270.
-
(2008)
Int J Pharm
, vol.351
, pp. 259-270
-
-
Hongrapipat, J.1
Kopecková, P.2
Prakongpan, S.3
Kopecek, J.4
-
75
-
-
14144249536
-
Efcacy and safety of tositumomab and iodine-131 tositumomab (Bexxar) in B-cell lymphoma, progressive after rituximab
-
Horning SJ, Younes A, Jain V, Kroll S, Lucas J, Podolof D, Goris M. (2005). Efcacy and safety of tositumomab and iodine-131 tositumomab (Bexxar) in B-cell lymphoma, progressive after rituximab. J Clin Oncol, 23, 712-719.
-
(2005)
J Clin Oncol
, vol.23
, pp. 712-719
-
-
Horning, S.J.1
Younes, A.2
Jain, V.3
Kroll, S.4
Lucas, J.5
Podolof, D.6
Goris, M.7
-
76
-
-
0020488877
-
Interactions of liposomes with the reticuloendothelial system. II: Nonspecifc and receptor-mediated uptake of liposomes by mouse peritoneal macrophages
-
Hsu MJ, Juliano RL. (1982). Interactions of liposomes with the reticuloendothelial system. II: Nonspecifc and receptor-mediated uptake of liposomes by mouse peritoneal macrophages. Biochim Biophys Acta, 720, 411-419.
-
(1982)
Biochim Biophys Acta
, vol.720
, pp. 411-419
-
-
Hsu, M.J.1
Juliano, R.L.2
-
77
-
-
80052509765
-
Gemtuzumab ozogamicin in non-acute promyelocytic acute myeloid leukemia
-
Hütter ML, Schlenk RF. (2011). Gemtuzumab ozogamicin in non-acute promyelocytic acute myeloid leukemia. Expert Opin Biol Ter, 11, 1369-1380.
-
(2011)
Expert Opin Biol ter
, vol.11
, pp. 1369-1380
-
-
Hütter, M.L.1
Schlenk, R.F.2
-
78
-
-
79952121979
-
Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion
-
Iliopoulos D, Hirsch HA, Wang G, Struhl K. (2011). Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion. Proc Natl Acad Sci USA, 108, 1397-1402.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 1397-1402
-
-
Iliopoulos, D.1
Hirsch, H.A.2
Wang, G.3
Struhl, K.4
-
79
-
-
0023481357
-
Transport of molecules across tumor vasculature
-
Jain RK. (1987). Transport of molecules across tumor vasculature. Cancer Metastasis Rev, 6, 559-593.
-
(1987)
Cancer Metastasis Rev
, vol.6
, pp. 559-593
-
-
Jain, R.K.1
-
80
-
-
0023909330
-
Determinants of tumor blood fow: A review
-
Jain RK. (1988). Determinants of tumor blood fow: a review. Cancer Res, 48, 2641-2658.
-
(1988)
Cancer Res
, vol.48
, pp. 2641-2658
-
-
Jain, R.K.1
-
81
-
-
0032580493
-
Delivery of molecular and cellular medicine to solid tumors
-
Jain RK. (1998). Delivery of molecular and cellular medicine to solid tumors. J Control Release, 53, 49-67.
-
(1998)
J Control Release
, vol.53
, pp. 49-67
-
-
Jain, R.K.1
-
82
-
-
0036548794
-
Dissecting tumour pathophysiology using intravital microscopy
-
Jain RK, Munn LL, Fukumura D. (2002). Dissecting tumour pathophysiology using intravital microscopy. Nat Rev Cancer, 2, 266-276.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 266-276
-
-
Jain, R.K.1
Munn, L.L.2
Fukumura, D.3
-
83
-
-
34047260282
-
Efect of vascular normalization by antiangiogenic therapy on interstitial hypertension, peritumor edema, and lymphatic metastasis: Insights from a mathematical model
-
Jain RK, Tong RT, Munn LL. (2007). Efect of vascular normalization by antiangiogenic therapy on interstitial hypertension, peritumor edema, and lymphatic metastasis: insights from a mathematical model. Cancer Res, 67, 2729-2735.
-
(2007)
Cancer Res
, vol.67
, pp. 2729-2735
-
-
Jain, R.K.1
Tong, R.T.2
Munn, L.L.3
-
85
-
-
77955635233
-
Cancer statistics, 2010
-
Jemal A, Siegel R, Xu J, Ward E. (2010). Cancer statistics, 2010. CA Cancer J Clin, 60, 277-300.
-
(2010)
CA Cancer J Clin
, vol.60
, pp. 277-300
-
-
Jemal, A.1
Siegel, R.2
Xu, J.3
Ward, E.4
-
86
-
-
61849184284
-
Synthesis and evaluation of multivalent branched HPMA copolymer-Fab' conjugates targeted to the B-cell antigen CD20
-
Johnson RN, Kopecková P, Kopecek J. (2009). Synthesis and evaluation of multivalent branched HPMA copolymer-Fab' conjugates targeted to the B-cell antigen CD20. Bioconjug Chem, 20, 129-137.
-
(2009)
Bioconjug Chem
, vol.20
, pp. 129-137
-
-
Johnson, R.N.1
Kopecková, P.2
Kopecek, J.3
-
87
-
-
0026739369
-
Micropharmacology of monoclonal antibodies in solid tumors: Direct experimental evidence for a binding site barrier
-
Juweid M, Neumann R, Paik C, Perez-Bacete MJ, Sato J, van Osdol W, Weinstein JN. (1992). Micropharmacology of monoclonal antibodies in solid tumors: direct experimental evidence for a binding site barrier. Cancer Res, 52, 5144-5153.
-
(1992)
Cancer Res
, vol.52
, pp. 5144-5153
-
-
Juweid, M.1
Neumann, R.2
Paik, C.3
Perez-Bacete, M.J.4
Sato, J.5
Van Osdol, W.6
Weinstein, J.N.7
-
88
-
-
0038488950
-
A multigenic program mediating breast cancer metastasis to bone
-
Kang Y, Siegel PM, Shu W, Drobnjak M, Kakonen SM, Cordón-Cardo C, Guise TA, Massagué J. (2003). A multigenic program mediating breast cancer metastasis to bone. Cancer Cell, 3, 537-549.
-
(2003)
Cancer Cell
, vol.3
, pp. 537-549
-
-
Kang, Y.1
Siegel, P.M.2
Shu, W.3
Drobnjak, M.4
Kakonen, S.M.5
Cordón-Cardo, C.6
Guise, T.A.7
Massagué, J.8
-
89
-
-
33847635618
-
Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-beta signaling
-
Kano MR, Bae Y, Iwata C, Morishita Y, Yashiro M, Oka M, Fujii T, Komuro A, Kiyono K, Kaminishi M, Hirakawa K, Ouchi Y, Nishiyama N, Kataoka K, Miyazono K. (2007). Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-beta signaling. Proc Natl Acad Sci USA, 104, 3460-3465.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 3460-3465
-
-
Kano, M.R.1
Bae, Y.2
Iwata, C.3
Morishita, Y.4
Yashiro, M.5
Oka, M.6
Fujii, T.7
Komuro, A.8
Kiyono, K.9
Kaminishi, M.10
Hirakawa, K.11
Ouchi, Y.12
Nishiyama, N.13
Kataoka, K.14
Miyazono, K.15
-
90
-
-
6044243650
-
Hedgehog signalling in prostate regeneration, neoplasia and metastasis
-
Karhadkar SS, Bova GS, Abdallah N, Dhara S, Gardner D, Maitra A, Isaacs JT, Berman DM, Beachy PA. (2004). Hedgehog signalling in prostate regeneration, neoplasia and metastasis. Nature, 431, 707-712.
-
(2004)
Nature
, vol.431
, pp. 707-712
-
-
Karhadkar, S.S.1
Bova, G.S.2
Abdallah, N.3
Dhara, S.4
Gardner, D.5
Maitra, A.6
Isaacs, J.T.7
Berman, D.M.8
Beachy, P.A.9
-
91
-
-
33746172167
-
Antibody targeting of long-circulating lipidic nanoparticles does not increase tumor localization but does increase internalization in animal models
-
Kirpotin DB, Drummond DC, Shao Y, Shalaby MR, Hong K, Nielsen UB, Marks JD, Benz CC, Park JW. (2006). Antibody targeting of long-circulating lipidic nanoparticles does not increase tumor localization but does increase internalization in animal models. Cancer Res, 66, 6732-6740.
-
(2006)
Cancer Res
, vol.66
, pp. 6732-6740
-
-
Kirpotin, D.B.1
Drummond, D.C.2
Shao, Y.3
Shalaby, M.R.4
Hong, K.5
Nielsen, U.B.6
Marks, J.D.7
Benz, C.C.8
Park, J.W.9
-
92
-
-
63049102497
-
Parallel progression of primary tumours and metastases
-
Klein CA. (2009). Parallel progression of primary tumours and metastases. Nat Rev Cancer, 9, 302-312.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 302-312
-
-
Klein, C.A.1
-
93
-
-
75749149269
-
HPMA copolymers: Origins, early developments, present, and future
-
Kopecek J, Kopecková P. (2010). HPMA copolymers: origins, early developments, present, and future. Adv Drug Deliv Rev, 62, 122-149.
-
(2010)
Adv Drug Deliv Rev
, vol.62
, pp. 122-149
-
-
Kopecek, J.1
Kopecková, P.2
-
94
-
-
38549131901
-
GATA-3 links tumor diferentiation and dissemination in a luminal breast cancer model
-
Kouros-Mehr H, Bechis SK, Slorach EM, Littlepage LE, Egeblad M, Ewald AJ, Pai SY, Ho IC, Werb Z. (2008). GATA-3 links tumor diferentiation and dissemination in a luminal breast cancer model. Cancer Cell, 13, 141-152.
-
(2008)
Cancer Cell
, vol.13
, pp. 141-152
-
-
Kouros-Mehr, H.1
Bechis, S.K.2
Slorach, E.M.3
Littlepage, L.E.4
Egeblad, M.5
Ewald, A.J.6
Pai, S.Y.7
Ho, I.C.8
Werb, Z.9
-
95
-
-
84869496001
-
Analysis on the current status of targeted drug delivery to tumors
-
DOI: 10.1016/j. jconrel.2012.07.010
-
Kwon IK, Lee SC, Han B, Park K. (2012). Analysis on the current status of targeted drug delivery to tumors. J Control Release, DOI: 10.1016/j. jconrel.2012.07.010.
-
(2012)
J Control Release
-
-
Kwon, I.K.1
Lee, S.C.2
Han, B.3
Park, K.4
-
96
-
-
3042687629
-
Antitumor activity of a homing peptide that targets tumor lymphatics and tumor cells
-
Laakkonen P, Akerman ME, Biliran H, Yang M, Ferrer F, Karpanen T, Hofman RM, Ruoslahti E. (2004). Antitumor activity of a homing peptide that targets tumor lymphatics and tumor cells. Proc Natl Acad Sci USA, 101, 9381-9386.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 9381-9386
-
-
Laakkonen, P.1
Akerman, M.E.2
Biliran, H.3
Yang, M.4
Ferrer, F.5
Karpanen, T.6
Hofman, R.M.7
Ruoslahti, E.8
-
97
-
-
75749134040
-
Improving the efcacy of combined modality anticancer therapy using HPMA copolymer-based nanomedicine formulations
-
Lammers T. (2010). Improving the efcacy of combined modality anticancer therapy using HPMA copolymer-based nanomedicine formulations. Adv Drug Deliv Rev, 62, 203-230.
-
(2010)
Adv Drug Deliv Rev
, vol.62
, pp. 203-230
-
-
Lammers, T.1
-
98
-
-
33846806033
-
Efect of radiotherapy and hyperthermia on the tumor accumulation of HPMA copolymer-based drug delivery systems
-
Lammers T, Peschke P, Kühnlein R, Šubr V, Ulbrich K, Debus J, Huber P, Hennink W, Storm G. (2007). Efect of radiotherapy and hyperthermia on the tumor accumulation of HPMA copolymer-based drug delivery systems. J Control Release, 117, 333-341.
-
(2007)
J Control Release
, vol.117
, pp. 333-341
-
-
Lammers, T.1
Peschke, P.2
Kühnlein, R.3
Šubr, V.4
Ulbrich, K.5
Debus, J.6
Huber, P.7
Hennink, W.8
Storm, G.9
-
99
-
-
48349107149
-
Tumour-targeted nanomedicines: Principles and practice
-
Lammers T, Hennink WE, Storm G. (2008). Tumour-targeted nanomedicines: principles and practice. Br J Cancer, 99, 392-397.
-
(2008)
Br J Cancer
, vol.99
, pp. 392-397
-
-
Lammers, T.1
Hennink, W.E.2
Storm, G.3
-
100
-
-
67349283045
-
Simultaneous delivery of doxorubicin and gemcitabine to tumors in vivo using prototypic polymeric drug carriers
-
Lammers T, Šubr V, Ulbrich K, Peschke P, Huber PE, Hennink WE, Storm G. (2009). Simultaneous delivery of doxorubicin and gemcitabine to tumors in vivo using prototypic polymeric drug carriers. Biomaterials, 30, 3466-3475.
-
(2009)
Biomaterials
, vol.30
, pp. 3466-3475
-
-
Lammers, T.1
Šubr, V.2
Ulbrich, K.3
Peschke, P.4
Huber, P.E.5
Hennink, W.E.6
Storm, G.7
-
101
-
-
84862698355
-
Drug targeting to tumors: Principles, pitfalls and (pre-) clinical progress
-
Lammers T, Kiessling F, Hennink WE, Storm G. (2012). Drug targeting to tumors: principles, pitfalls and (pre-) clinical progress. J Control Release, 161, 175-187.
-
(2012)
J Control Release
, vol.161
, pp. 175-187
-
-
Lammers, T.1
Kiessling, F.2
Hennink, W.E.3
Storm, G.4
-
102
-
-
0028793693
-
Efect of ionizing radiation on AP-1 binding activity and basic fbroblast growth factor gene expression in drug-sensitive human breast carcinoma MCF-7 and multidrug-resistant MCF-7/ADR cells
-
Lee YJ, Galoforo SS, Berns CM, Erdos G, Gupta AK, Ways DK, Corry PM. (1995). Efect of ionizing radiation on AP-1 binding activity and basic fbroblast growth factor gene expression in drug-sensitive human breast carcinoma MCF-7 and multidrug-resistant MCF-7/ADR cells. J Biol Chem, 270, 28790-28796.
-
(1995)
J Biol Chem
, vol.270
, pp. 28790-28796
-
-
Lee, Y.J.1
Galoforo, S.S.2
Berns, C.M.3
Erdos, G.4
Gupta, A.K.5
Ways, D.K.6
Corry, P.M.7
-
103
-
-
0034662608
-
Absence of functional lymphatics within a murine sarcoma: A molecular and functional evaluation
-
Leu AJ, Berk DA, Lymboussaki A, Alitalo K, Jain RK. (2000). Absence of functional lymphatics within a murine sarcoma: a molecular and functional evaluation. Cancer Res, 60, 4324-4327.
-
(2000)
Cancer Res
, vol.60
, pp. 4324-4327
-
-
Leu, A.J.1
Berk, D.A.2
Lymboussaki, A.3
Alitalo, K.4
Jain, R.K.5
-
104
-
-
0024818355
-
Vascular endothelial growth factor is a secreted angiogenic mitogen
-
Leung DW, Cachianes G, Kuang WJ, Goeddel DV, Ferrara N. (1989). Vascular endothelial growth factor is a secreted angiogenic mitogen. Science, 246, 1306-1309.
-
(1989)
Science
, vol.246
, pp. 1306-1309
-
-
Leung, D.W.1
Cachianes, G.2
Kuang, W.J.3
Goeddel, D.V.4
Ferrara, N.5
-
105
-
-
0026459493
-
Angiogenesis, microvascular architecture, microhemodynamics, and interstitial fuid pressure during early growth of human adenocarcinoma LS174T in SCID mice
-
Leunig M, Yuan F, Menger MD, Boucher Y, Goetz AE, Messmer K, Jain RK. (1992). Angiogenesis, microvascular architecture, microhemodynamics, and interstitial fuid pressure during early growth of human adenocarcinoma LS174T in SCID mice. Cancer Res, 52, 6553-6560.
-
(1992)
Cancer Res
, vol.52
, pp. 6553-6560
-
-
Leunig, M.1
Yuan, F.2
Menger, M.D.3
Boucher, Y.4
Goetz, A.E.5
Messmer, K.6
Jain, R.K.7
-
106
-
-
0033927015
-
Tumor irradiation enhances the tumor-specifc distribution of poly(L-glutamic acid)-conjugated paclitaxel and its antitumor efcacy
-
Li C, Ke S, Wu QP, Tansey W, Hunter N, Buchmiller LM, Milas L, Charnsangavej C, Wallace S. (2000). Tumor irradiation enhances the tumor-specifc distribution of poly(L-glutamic acid)-conjugated paclitaxel and its antitumor efcacy. Clin Cancer Res, 6, 2829-2834.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 2829-2834
-
-
Li, C.1
Ke, S.2
Wu, Q.P.3
Tansey, W.4
Hunter, N.5
Buchmiller, L.M.6
Milas, L.7
Charnsangavej, C.8
Wallace, S.9
-
107
-
-
51049104302
-
Pharmacokinetics and biodistribution of nanoparticles
-
Li SD, Huang L. (2008). Pharmacokinetics and biodistribution of nanoparticles. Mol Pharm, 5, 496-504.
-
(2008)
Mol Pharm
, vol.5
, pp. 496-504
-
-
Li, S.D.1
Huang, L.2
-
108
-
-
79952341098
-
A polymeric nanoparticle formulation of curcumin inhibits growth, clonogenicity and stem-like fraction in malignant brain tumors
-
Lim KJ, Bisht S, Bar EE, Maitra A, Eberhart CG. (2011). A polymeric nanoparticle formulation of curcumin inhibits growth, clonogenicity and stem-like fraction in malignant brain tumors. Cancer Biol Ter, 11, 464-473.
-
(2011)
Cancer Biol ter
, vol.11
, pp. 464-473
-
-
Lim, K.J.1
Bisht, S.2
Bar, E.E.3
Maitra, A.4
Eberhart, C.G.5
-
109
-
-
67249102448
-
Biorecognition and subcellular trafcking of HPMA copolymer-anti-PSMA antibody conjugates by prostate cancer cells
-
Liu J, Kopecková P, Bühler P, Wolf P, Pan H, Bauer H, Elsässer-Beile U, Kopecek J. (2009). Biorecognition and subcellular trafcking of HPMA copolymer-anti-PSMA antibody conjugates by prostate cancer cells. Mol Pharm, 6, 959-970.
-
(2009)
Mol Pharm
, vol.6
, pp. 959-970
-
-
Liu, J.1
Kopecková, P.2
Bühler, P.3
Wolf, P.4
Pan, H.5
Bauer, H.6
Elsässer-Beile, U.7
Kopecek, J.8
-
110
-
-
0344146604
-
Polymerizable Fab' antibody fragments for targeting of anticancer drugs
-
Lu ZR, Kopecková P, Kopecek J. (1999). Polymerizable Fab' antibody fragments for targeting of anticancer drugs. Nat Biotechnol, 17, 1101-1104.
-
(1999)
Nat Biotechnol
, vol.17
, pp. 1101-1104
-
-
Lu, Z.R.1
Kopecková, P.2
Kopecek, J.3
-
111
-
-
79955017504
-
Biodegradable Multiblock Poly[N-(2-hydroxypropyl)methacrylamide] via Reversible Addition-Fragmentation Chain Transfer Polymerization and Click Chemistry
-
Luo K, Yang J, Kopecková P, Kopecek J. (2011). Biodegradable Multiblock Poly[N-(2-hydroxypropyl)methacrylamide] via Reversible Addition-Fragmentation Chain Transfer Polymerization and Click Chemistry. Macromolecules, 44, 2481-2488.
-
(2011)
Macromolecules
, vol.44
, pp. 2481-2488
-
-
Luo, K.1
Yang, J.2
Kopecková, P.3
Kopecek, J.4
-
112
-
-
0242392015
-
Acute and long-term toxicity following radiotherapy alone or in combination with chemotherapy for locally advanced cervical cancer
-
Maduro JH, Pras E, Willemse PH, de Vries EG. (2003). Acute and long-term toxicity following radiotherapy alone or in combination with chemotherapy for locally advanced cervical cancer. Cancer Treat Rev, 29, 471-488.
-
(2003)
Cancer Treat Rev
, vol.29
, pp. 471-488
-
-
Maduro, J.H.1
Pras, E.2
Willemse, P.H.3
De Vries, E.G.4
-
113
-
-
0023821387
-
Purifcation and identifcation of [hydroxyprolyl3]bradykinin in ascitic fuid from a patient with gastric cancer
-
Maeda H, Matsumura Y, Kato H. (1988). Purifcation and identifcation of [hydroxyprolyl3]bradykinin in ascitic fuid from a patient with gastric cancer. J Biol Chem, 263, 16051-16054.
-
(1988)
J Biol Chem
, vol.263
, pp. 16051-16054
-
-
Maeda, H.1
Matsumura, Y.2
Kato, H.3
-
114
-
-
0034000453
-
Tumor vascular permeability and the EPR efect in macromolecular therapeutics: A review
-
Maeda H, Wu J, Sawa T, Matsumura Y, Hori K. (2000). Tumor vascular permeability and the EPR efect in macromolecular therapeutics: a review. J Control Release, 65, 271-284.
-
(2000)
J Control Release
, vol.65
, pp. 271-284
-
-
Maeda, H.1
Wu, J.2
Sawa, T.3
Matsumura, Y.4
Hori, K.5
-
115
-
-
33745782940
-
HPMA copolymer-bound doxorubicin induces apoptosis in ovarian carcinoma cells by the disruption of mitochondrial function
-
Malugin A, Kopecková P, Kopecek J. (2006). HPMA copolymer-bound doxorubicin induces apoptosis in ovarian carcinoma cells by the disruption of mitochondrial function. Mol Pharm, 3, 351-361.
-
(2006)
Mol Pharm
, vol.3
, pp. 351-361
-
-
Malugin, A.1
Kopecková, P.2
Kopecek, J.3
-
116
-
-
79961032358
-
Mesoporous silica nanoparticles as drug delivery systems for targeted inhibition of Notch signaling in cancer
-
Mamaeva V, Rosenholm JM, Bate-Eya LT, Bergman L, Peuhu E, Duchanoy A, Fortelius LE, Landor S, Toivola DM, Lindén M, Sahlgren C. (2011). Mesoporous silica nanoparticles as drug delivery systems for targeted inhibition of Notch signaling in cancer. Mol Ter, 19, 1538-1546.
-
(2011)
Mol ter
, vol.19
, pp. 1538-1546
-
-
Mamaeva, V.1
Rosenholm, J.M.2
Bate-Eya, L.T.3
Bergman, L.4
Peuhu, E.5
Duchanoy, A.6
Fortelius, L.E.7
Landor, S.8
Toivola, D.M.9
Lindén, M.10
Sahlgren, C.11
-
117
-
-
0022858683
-
A new concept for macromolecular therapeutics in cancer chemotherapy: Mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs
-
Matsumura Y, Maeda H. (1986). A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs. Cancer Res, 46, 6387-6392.
-
(1986)
Cancer Res
, vol.46
, pp. 6387-6392
-
-
Matsumura, Y.1
Maeda, H.2
-
118
-
-
67449084321
-
Preclinical and clinical studies of anticancer agent-incorporating polymer micelles
-
Matsumura Y, Kataoka K. (2009). Preclinical and clinical studies of anticancer agent-incorporating polymer micelles. Cancer Sci, 100, 572-579.
-
(2009)
Cancer Sci
, vol.100
, pp. 572-579
-
-
Matsumura, Y.1
Kataoka, K.2
-
119
-
-
33645066093
-
Degradation of fbrillar collagen in a human melanoma xenograft improves the efcacy of an oncolytic herpes simplex virus vector
-
McKee TD, Grandi P, Mok W, Alexandrakis G, Insin N, Zimmer JP, Bawendi MG, Boucher Y, Breakefeld XO, Jain RK. (2006). Degradation of fbrillar collagen in a human melanoma xenograft improves the efcacy of an oncolytic herpes simplex virus vector. Cancer Res, 66, 2509-2513.
-
(2006)
Cancer Res
, vol.66
, pp. 2509-2513
-
-
McKee, T.D.1
Grandi, P.2
Mok, W.3
Alexandrakis, G.4
Insin, N.5
Zimmer, J.P.6
Bawendi, M.G.7
Boucher, Y.8
Breakefeld, X.O.9
Jain, R.K.10
-
120
-
-
8444247084
-
Modulation of notch processing by gamma-secretase inhibitors causes intestinal goblet cell metaplasia and induction of genes known to specify gut secretory lineage diferentiation
-
Milano J, McKay J, Dagenais C, Foster-Brown L, Pognan F, Gadient R, Jacobs RT, Zacco A, Greenberg B, Ciaccio PJ. (2004). Modulation of notch processing by gamma-secretase inhibitors causes intestinal goblet cell metaplasia and induction of genes known to specify gut secretory lineage diferentiation. Toxicol Sci, 82, 341-358.
-
(2004)
Toxicol Sci
, vol.82
, pp. 341-358
-
-
Milano, J.1
McKay, J.2
Dagenais, C.3
Foster-Brown, L.4
Pognan, F.5
Gadient, R.6
Jacobs, R.T.7
Zacco, A.8
Greenberg, B.9
Ciaccio, P.J.10
-
121
-
-
79961079796
-
Antiangiogenic antitumor activity of HPMA copolymer-paclitaxel- alendronate conjugate on breast cancer bone metastasis mouse model
-
Miller K, Eldar-Boock A, Polyak D, Segal E, Benayoun L, Shaked Y, Satchi-Fainaro R. (2011). Antiangiogenic antitumor activity of HPMA copolymer-paclitaxel-alendronate conjugate on breast cancer bone metastasis mouse model. Mol Pharm, 8, 1052-1062.
-
(2011)
Mol Pharm
, vol.8
, pp. 1052-1062
-
-
Miller, K.1
Eldar-Boock, A.2
Polyak, D.3
Segal, E.4
Benayoun, L.5
Shaked, Y.6
Satchi-Fainaro, R.7
-
123
-
-
0344142519
-
Chronic exposure to HPMA copolymer-bound adriamycin does not induce multidrug resistance in a human ovarian carcinoma cell line
-
Minko T, Kopecková P, Kopecek J. (1999). Chronic exposure to HPMA copolymer-bound adriamycin does not induce multidrug resistance in a human ovarian carcinoma cell line. J Control Release, 59, 133-148.
-
(1999)
J Control Release
, vol.59
, pp. 133-148
-
-
Minko, T.1
Kopecková, P.2
Kopecek, J.3
-
124
-
-
0034049291
-
Efcacy of the chemotherapeutic action of HPMA copolymer-bound doxorubicin in a solid tumor model of ovarian carcinoma
-
Minko T, Kopecková P, Kopecek J. (2000). Efcacy of the chemotherapeutic action of HPMA copolymer-bound doxorubicin in a solid tumor model of ovarian carcinoma. Int J Cancer, 86, 108-117.
-
(2000)
Int J Cancer
, vol.86
, pp. 108-117
-
-
Minko, T.1
Kopecková, P.2
Kopecek, J.3
-
125
-
-
0035962380
-
Preliminary evaluation of caspases-dependent apoptosis signaling pathways of free and HPMA copolymer-bound doxorubicin in human ovarian carcinoma cells
-
Minko T, Kopecková P, Kopecek J. (2001). Preliminary evaluation of caspases-dependent apoptosis signaling pathways of free and HPMA copolymer-bound doxorubicin in human ovarian carcinoma cells. J Control Release, 71, 227-237.
-
(2001)
J Control Release
, vol.71
, pp. 227-237
-
-
Minko, T.1
Kopecková, P.2
Kopecek, J.3
-
126
-
-
0036675220
-
Metastasis to bone: Causes, consequences and therapeutic opportunities
-
Mundy GR. (2002). Metastasis to bone: causes, consequences and therapeutic opportunities. Nat Rev Cancer, 2, 584-593.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 584-593
-
-
Mundy, G.R.1
-
127
-
-
34748834693
-
Multidrug resistance inhibition by antisense oligonucleotide against MDR1/mRNA in P-glycoprotein expressing leukemic cells
-
Nadali F, Pourfathollah AA, Alimoghaddam K, Nikougoftar M, Rostami S, Dizaji A, Azizi E, Zomorodipour A, Ghavamzadeh A. (2007). Multidrug resistance inhibition by antisense oligonucleotide against MDR1/mRNA in P-glycoprotein expressing leukemic cells. Hematology, 12, 393-401.
-
(2007)
Hematology
, vol.12
, pp. 393-401
-
-
Nadali, F.1
Pourfathollah, A.A.2
Alimoghaddam, K.3
Nikougoftar, M.4
Rostami, S.5
Dizaji, A.6
Azizi, E.7
Zomorodipour, A.8
Ghavamzadeh, A.9
-
128
-
-
79953740850
-
Detection of macrophages in aortic aneurysms by nanoparticle positron emission tomography-computed tomography
-
Nahrendorf M, Keliher E, Marinelli B, Leuschner F, Robbins CS, Gerszten RE, Pittet MJ, Swirski FK, Weissleder R. (2011). Detection of macrophages in aortic aneurysms by nanoparticle positron emission tomography-computed tomography. Arterioscler Tromb Vasc Biol, 31, 750-757.
-
(2011)
Arterioscler Tromb Vasc Biol
, vol.31
, pp. 750-757
-
-
Nahrendorf, M.1
Keliher, E.2
Marinelli, B.3
Leuschner, F.4
Robbins, C.S.5
Gerszten, R.E.6
Pittet, M.J.7
Swirski, F.K.8
Weissleder, R.9
-
129
-
-
20344367537
-
Tumour vascular targeting
-
Neri D, Bicknell R. (2005). Tumour vascular targeting. Nat Rev Cancer, 5, 436-446.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 436-446
-
-
Neri, D.1
Bicknell, R.2
-
130
-
-
63049090100
-
Metastasis: From dissemination to organ-specifc colonization
-
Nguyen DX, Bos PD, Massagué J. (2009). Metastasis: from dissemination to organ-specifc colonization. Nat Rev Cancer, 9, 274-284.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 274-284
-
-
Nguyen, D.X.1
Bos, P.D.2
Massagué, J.3
-
131
-
-
77749254873
-
Surgery with molecular fuorescence imaging using activatable cell-penetrating peptides decreases residual cancer and improves survival
-
Nguyen QT, Olson ES, Aguilera TA, Jiang T, Scadeng M, Ellies LG, Tsien RY. (2010). Surgery with molecular fuorescence imaging using activatable cell-penetrating peptides decreases residual cancer and improves survival. Proc Natl Acad Sci USA, 107, 4317-4322.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 4317-4322
-
-
Nguyen, Q.T.1
Olson, E.S.2
Aguilera, T.A.3
Jiang, T.4
Scadeng, M.5
Ellies, L.G.6
Tsien, R.Y.7
-
132
-
-
0344412936
-
Free and N-(2-hydroxypropyl)methacrylamide copolymer-bound geldanamycin derivative induce diferent stress responses in A2780 human ovarian carcinoma cells
-
Nishiyama N, Nori A, Malugin A, Kasuya Y, Kopecková P, Kopecek J. (2003). Free and N-(2-hydroxypropyl)methacrylamide copolymer-bound geldanamycin derivative induce diferent stress responses in A2780 human ovarian carcinoma cells. Cancer Res, 63, 7876-7882.
-
(2003)
Cancer Res
, vol.63
, pp. 7876-7882
-
-
Nishiyama, N.1
Nori, A.2
Malugin, A.3
Kasuya, Y.4
Kopecková, P.5
Kopecek, J.6
-
133
-
-
0031959490
-
Early phase tumor accumulation of macromolecules: A great diference in clearance rate between tumor and normal tissues
-
Noguchi Y, Wu J, Duncan R, Strohalm J, Ulbrich K, Akaike T, Maeda H. (1998). Early phase tumor accumulation of macromolecules: a great diference in clearance rate between tumor and normal tissues. Jpn J Cancer Res, 89, 307-314.
-
(1998)
Jpn J Cancer Res
, vol.89
, pp. 307-314
-
-
Noguchi, Y.1
Wu, J.2
Duncan, R.3
Strohalm, J.4
Ulbrich, K.5
Akaike, T.6
Maeda, H.7
-
134
-
-
0031861021
-
Pegylated-liposomal doxorubicin versus doxorubicin, bleomycin, and vincristine in the treatment of AIDS-related Kaposi's sarcoma: Results of a randomized phase III clinical trial
-
Northfelt DW, Dezube BJ, Tommes JA, Miller BJ, Fischl MA, Friedman-Kien A, Kaplan LD, Du Mond C, Mamelok RD, Henry DH. (1998). Pegylated-liposomal doxorubicin versus doxorubicin, bleomycin, and vincristine in the treatment of AIDS-related Kaposi's sarcoma: results of a randomized phase III clinical trial. J Clin Oncol, 16, 2445-2451.
-
(1998)
J Clin Oncol
, vol.16
, pp. 2445-2451
-
-
Northfelt, D.W.1
Dezube, B.J.2
Tommes, J.A.3
Miller, B.J.4
Fischl, M.A.5
Friedman-Kien, A.6
Kaplan, L.D.7
Du Mond, C.8
Mamelok, R.D.9
Henry, D.H.10
-
135
-
-
0017167185
-
The clonal evolution of tumor cell populations
-
Nowell PC. (1976). The clonal evolution of tumor cell populations. Science, 194, 23-28.
-
(1976)
Science
, vol.194
, pp. 23-28
-
-
Nowell, P.C.1
-
136
-
-
70350070378
-
ProLindac (AP5346): A review of the development of an HPMA DACH platinum Polymer Terapeutic
-
Nowotnik DP, Cvitkovic E. (2009). ProLindac (AP5346): a review of the development of an HPMA DACH platinum Polymer Terapeutic. Adv Drug Deliv Rev, 61, 1214-1219.
-
(2009)
Adv Drug Deliv Rev
, vol.61
, pp. 1214-1219
-
-
Nowotnik, D.P.1
Cvitkovic, E.2
-
137
-
-
0021355544
-
Extravascular difusion in normal and neoplastic tissues
-
Nugent LJ, Jain RK. (1984). Extravascular difusion in normal and neoplastic tissues. Cancer Res, 44, 238-244.
-
(1984)
Cancer Res
, vol.44
, pp. 238-244
-
-
Nugent, L.J.1
Jain, R.K.2
-
138
-
-
33846100356
-
A human colon cancer cell capable of initiating tumour growth in immunodefcient mice
-
O'Brien CA, Pollett A, Gallinger S, Dick JE. (2007). A human colon cancer cell capable of initiating tumour growth in immunodefcient mice. Nature, 445, 106-110.
-
(2007)
Nature
, vol.445
, pp. 106-110
-
-
O'Brien, C.A.1
Pollett, A.2
Gallinger, S.3
Dick, J.E.4
-
139
-
-
11144357506
-
Reduced cardiotoxicity and comparable efcacy in a phase III trial of pegylated liposomal doxorubicin HCl (CAELYX/Doxil) versus conventional doxorubicin for frst-line treatment of metastatic breast cancer
-
O'Brien ME, Wigler N, Inbar M, Rosso R, Grischke E, Santoro A, Catane R, Kieback DG, Tomczak P, Ackland SP, Orlandi F, Mellars L, Alland L, Tendler C; CAELYX Breast Cancer Study Group. (2004). Reduced cardiotoxicity and comparable efcacy in a phase III trial of pegylated liposomal doxorubicin HCl (CAELYX/Doxil) versus conventional doxorubicin for frst-line treatment of metastatic breast cancer. Ann Oncol, 15, 440-449.
-
(2004)
Ann Oncol
, vol.15
, pp. 440-449
-
-
O'Brien, M.E.1
Wigler, N.2
Inbar, M.3
Rosso, R.4
Grischke, E.5
Santoro, A.6
Catane, R.7
Kieback, D.G.8
Tomczak, P.9
Ackland, S.P.10
Orlandi, F.11
Mellars, L.12
Alland, L.13
Tendler, C.14
-
140
-
-
50349101826
-
Randomized phase III trial comparing single-agent paclitaxel Poliglumex (CT-2103, PPX) with single-agent gemcitabine or vinorelbine for the treatment of PS 2 patients with chemotherapy-naïve advanced non-small cell lung cancer
-
O'Brien ME, Socinski MA, Popovich AY, Bondarenko IN, Tomova A, Bilynsky BT, Hotko YS, Ganul VL, Kostinsky IY, Eisenfeld AJ, Sandalic L, Oldham FB, Bandstra B, Sandler AB, Singer JW. (2008). Randomized phase III trial comparing single-agent paclitaxel Poliglumex (CT-2103, PPX) with single-agent gemcitabine or vinorelbine for the treatment of PS 2 patients with chemotherapy-naïve advanced non-small cell lung cancer. J Torac Oncol, 3, 728-734.
-
(2008)
J Torac Oncol
, vol.3
, pp. 728-734
-
-
O'Brien, M.E.1
Socinski, M.A.2
Popovich, A.Y.3
Bondarenko, I.N.4
Tomova, A.5
Bilynsky, B.T.6
Hotko, Y.S.7
Ganul, V.L.8
Kostinsky, I.Y.9
Eisenfeld, A.J.10
Sandalic, L.11
Oldham, F.B.12
Bandstra, B.13
Sandler, A.B.14
Singer, J.W.15
-
141
-
-
67149143399
-
Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer
-
Olive KP, Jacobetz MA, Davidson CJ, Gopinathan A, McIntyre D, Honess D, Madhu B, Goldgraben MA, Caldwell ME, Allard D, Frese KK, Denicola G, Feig C, Combs C, Winter SP, Ireland-Zecchini H, Reichelt S, Howat WJ, Chang A, Dhara M, Wang L, Rückert F, Grützmann R, Pilarsky C, Izeradjene K, Hingorani SR, Huang P, Davies SE, Plunkett W, Egorin M, Hruban RH, Whitebread N, McGovern K, Adams J, Iacobuzio-Donahue C, Grifths J, Tuveson DA. (2009). Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer. Science, 324, 1457-1461.
-
(2009)
Science
, vol.324
, pp. 1457-1461
-
-
Olive, K.P.1
Jacobetz, M.A.2
Davidson, C.J.3
Gopinathan, A.4
McIntyre, D.5
Honess, D.6
Madhu, B.7
Goldgraben, M.A.8
Caldwell, M.E.9
Allard, D.10
Frese, K.K.11
Denicola, G.12
Feig, C.13
Combs, C.14
Winter, S.P.15
Ireland-Zecchini, H.16
Reichelt, S.17
Howat, W.J.18
Chang, A.19
Dhara, M.20
Wang, L.21
Rückert, F.22
Grützmann, R.23
Pilarsky, C.24
Izeradjene, K.25
Hingorani, S.R.26
Huang, P.27
Davies, S.E.28
Plunkett, W.29
Egorin, M.30
Hruban, R.H.31
Whitebread, N.32
McGovern, K.33
Adams, J.34
Iacobuzio-Donahue, C.35
Grifths, J.36
Tuveson, D.A.37
more..
-
142
-
-
77749297971
-
Activatable cell penetrating peptides linked to nanoparticles as dual probes for in vivo fuorescence and MR imaging of proteases
-
Olson ES, Jiang T, Aguilera TA, Nguyen QT, Ellies LG, Scadeng M, Tsien RY. (2010). Activatable cell penetrating peptides linked to nanoparticles as dual probes for in vivo fuorescence and MR imaging of proteases. Proc Natl Acad Sci USA, 107, 4311-4316.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 4311-4316
-
-
Olson, E.S.1
Jiang, T.2
Aguilera, T.A.3
Nguyen, Q.T.4
Ellies, L.G.5
Scadeng, M.6
Tsien, R.Y.7
-
143
-
-
0032580444
-
Targetable HPMA copolymer-adriamycin conjugates. Recognition, internalization, and subcellular fate
-
Omelyanenko V, Kopecková P, Gentry C, Kopecek J. (1998a). Targetable HPMA copolymer-adriamycin conjugates. Recognition, internalization, and subcellular fate. J Control Release, 53, 25-37.
-
(1998)
J Control Release
, vol.53
, pp. 25-37
-
-
Omelyanenko, V.1
Kopecková, P.2
Gentry, C.3
Kopecek, J.4
-
144
-
-
0032498552
-
HPMA copolymer-anticancer drug-OV-TL16 antibody conjugates. II. Processing in epithelial ovarian carcinoma cells in vitro
-
Omelyanenko V, Gentry C, Kopecková P, Kopecek J. (1998b). HPMA copolymer-anticancer drug-OV-TL16 antibody conjugates. II. Processing in epithelial ovarian carcinoma cells in vitro. Int J Cancer, 75, 600-608.
-
(1998)
Int J Cancer
, vol.75
, pp. 600-608
-
-
Omelyanenko, V.1
Gentry, C.2
Kopecková, P.3
Kopecek, J.4
-
145
-
-
67651166902
-
Persistence of leukemia-initiating cells in a conditional knockin model of an imatinib-responsive myeloproliferative disorder
-
Oravecz-Wilson KI, Philips ST, Yilmaz OH, Ames HM, Li L, Crawford BD, Gauvin AM, Lucas PC, Sitwala K, Downing JR, Morrison SJ, Ross TS. (2009). Persistence of leukemia-initiating cells in a conditional knockin model of an imatinib-responsive myeloproliferative disorder. Cancer Cell, 16, 137-148.
-
(2009)
Cancer Cell
, vol.16
, pp. 137-148
-
-
Oravecz-Wilson, K.I.1
Philips, S.T.2
Yilmaz, O.H.3
Ames, H.M.4
Li, L.5
Crawford, B.D.6
Gauvin, A.M.7
Lucas, P.C.8
Sitwala, K.9
Downing, J.R.10
Morrison, S.J.11
Ross, T.S.12
-
146
-
-
0037036136
-
Lymphatic metastasis in the absence of functional intratumor lymphatics
-
Padera TP, Kadambi A, di Tomaso E, Carreira CM, Brown EB, Boucher Y, Choi NC, Mathisen D, Wain J, Mark EJ, Munn LL, Jain RK. (2002). Lymphatic metastasis in the absence of functional intratumor lymphatics. Science, 296, 1883-1886.
-
(2002)
Science
, vol.296
, pp. 1883-1886
-
-
Padera, T.P.1
Kadambi, A.2
Di Tomaso, E.3
Carreira, C.M.4
Brown, E.B.5
Boucher, Y.6
Choi, N.C.7
Mathisen, D.8
Wain, J.9
Mark, E.J.10
Munn, L.L.11
Jain, R.K.12
-
147
-
-
1542320497
-
Pathology: Cancer cells compress intratumour vessels
-
Padera TP, Stoll BR, Tooredman JB, Capen D, di Tomaso E, Jain RK. (2004). Pathology: cancer cells compress intratumour vessels. Nature, 427, 695.
-
(2004)
Nature
, vol.427
, pp. 695
-
-
Padera, T.P.1
Stoll, B.R.2
Tooredman, J.B.3
Capen, D.4
Di Tomaso, E.5
Jain, R.K.6
-
148
-
-
51049117949
-
Biodistribution and pharmacokinetic studies of bone-targeting N-(2-hydroxypropyl)methacrylamide copolymer-alendronate conjugates
-
Pan H, Sima M, Kopecková P, Wu K, Gao S, Liu J, Wang D, Miller SC, Kopecek J. (2008). Biodistribution and pharmacokinetic studies of bone-targeting N-(2-hydroxypropyl)methacrylamide copolymer-alendronate conjugates. Mol Pharm, 5, 548-558.
-
(2008)
Mol Pharm
, vol.5
, pp. 548-558
-
-
Pan, H.1
Sima, M.2
Kopecková, P.3
Wu, K.4
Gao, S.5
Liu, J.6
Wang, D.7
Miller, S.C.8
Kopecek, J.9
-
149
-
-
78651333306
-
Backbone degradable multiblock N-(2-hydroxypropyl)methacrylamide copolymer conjugates via reversible addition-fragmentation chain transfer polymerization and thiol-ene coupling reaction
-
Pan H, Yang J, Kopecková P, Kopecek J. (2011). Backbone degradable multiblock N-(2-hydroxypropyl)methacrylamide copolymer conjugates via reversible addition-fragmentation chain transfer polymerization and thiol-ene coupling reaction. Biomacromolecules, 12, 247-252.
-
(2011)
Biomacromolecules
, vol.12
, pp. 247-252
-
-
Pan, H.1
Yang, J.2
Kopecková, P.3
Kopecek, J.4
-
150
-
-
0033651234
-
The molecular and cellular biology of HER2/neu gene amplifcation/ overexpression and the clinical development of herceptin (trastuzumab) therapy for breast cancer
-
Pegram MD, Konecny G, Slamon DJ. (2000). The molecular and cellular biology of HER2/neu gene amplifcation/overexpression and the clinical development of herceptin (trastuzumab) therapy for breast cancer. Cancer Treat Res, 103, 57-75.
-
(2000)
Cancer Treat Res
, vol.103
, pp. 57-75
-
-
Pegram, M.D.1
Konecny, G.2
Slamon, D.J.3
-
151
-
-
0032899915
-
Morphometric analysis of bromodeoxyuridine distribution and cell density in the rat Dunning prostate tumor R3327-AT1 following treatment with radiation and/or hyperthermia
-
Peschke P, Klein V, Wolber G, Friedrich E, Hahn EW. (1999). Morphometric analysis of bromodeoxyuridine distribution and cell density in the rat Dunning prostate tumor R3327-AT1 following treatment with radiation and/or hyperthermia. Histol Histopathol, 14, 461-469.
-
(1999)
Histol Histopathol
, vol.14
, pp. 461-469
-
-
Peschke, P.1
Klein, V.2
Wolber, G.3
Friedrich, E.4
Hahn, E.W.5
-
152
-
-
0015014839
-
Diferentiation of malignant to benign cells
-
Pierce GB, Wallace C. (1971). Diferentiation of malignant to benign cells. Cancer Res, 31, 127-134.
-
(1971)
Cancer Res
, vol.31
, pp. 127-134
-
-
Pierce, G.B.1
Wallace, C.2
-
153
-
-
0032978690
-
Difusion of macromolecules in agarose gels: Comparison of linear and globular confgurations
-
Pluen A, Netti PA, Jain RK, Berk DA. (1999). Difusion of macromolecules in agarose gels: comparison of linear and globular confgurations. Biophys J, 77, 542-552.
-
(1999)
Biophys J
, vol.77
, pp. 542-552
-
-
Pluen, A.1
Netti, P.A.2
Jain, R.K.3
Berk, D.A.4
-
154
-
-
29344443251
-
The distribution of the anticancer drug Doxorubicin in relation to blood vessels in solid tumors
-
Primeau AJ, Rendon A, Hedley D, Lilge L, Tannock IF. (2005). The distribution of the anticancer drug Doxorubicin in relation to blood vessels in solid tumors. Clin Cancer Res, 11, 8782-8788.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 8782-8788
-
-
Primeau, A.J.1
Rendon, A.2
Hedley, D.3
Lilge, L.4
Tannock, I.F.5
-
155
-
-
84858602107
-
Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma
-
Provenzano PP, Cuevas C, Chang AE, Goel VK, Von Hof DD, Hingorani SR. (2012). Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma. Cancer Cell, 21, 418-429.
-
(2012)
Cancer Cell
, vol.21
, pp. 418-429
-
-
Provenzano, P.P.1
Cuevas, C.2
Chang, A.E.3
Goel, V.K.4
Von Hof, D.D.5
Hingorani, S.R.6
-
156
-
-
0019364294
-
Biochemical, morphological, and ultrastructural studies on the uptake of liposomes by murine macrophages
-
Raz A, Bucana C, Fogler WE, Poste G, Fidler IJ. (1981). Biochemical, morphological, and ultrastructural studies on the uptake of liposomes by murine macrophages. Cancer Res, 41, 487-494.
-
(1981)
Cancer Res
, vol.41
, pp. 487-494
-
-
Raz, A.1
Bucana, C.2
Fogler, W.E.3
Poste, G.4
Fidler, I.J.5
-
157
-
-
0000859980
-
Polymers containing enzymatically degradable bonds. 8. Degradation of oligopeptide sequences in N-(2-hydroxypropyl)methacrylamide copolymers by bovine spleen cathepsin B
-
Rejmanová P, Pohl J, Baudyš M, Kostka V, Kopecek J. (1983). Polymers containing enzymatically degradable bonds. 8. Degradation of oligopeptide sequences in N-(2-hydroxypropyl)methacrylamide copolymers by bovine spleen cathepsin B. Makromol Chem, 184, 2009-2020.
-
(1983)
Makromol Chem
, vol.184
, pp. 2009-2020
-
-
Rejmanová, P.1
Pohl, J.2
Baudyš, M.3
Kostka, V.4
Kopecek, J.5
-
158
-
-
51049115157
-
Overcoming multidrug resistance in human carcinoma cells by an antisense oligodeoxynucleotide-doxorubicin conjugate in vitro and in vivo
-
Ren Y, Wang Y, Zhang Y, Wei D. (2008). Overcoming multidrug resistance in human carcinoma cells by an antisense oligodeoxynucleotide-doxorubicin conjugate in vitro and in vivo. Mol Pharm, 5, 579-587.
-
(2008)
Mol Pharm
, vol.5
, pp. 579-587
-
-
Ren, Y.1
Wang, Y.2
Zhang, Y.3
Wei, D.4
-
159
-
-
0035499267
-
Stem cells, cancer, and cancer stem cells
-
Reya T, Morrison SJ, Clarke MF, Weissman IL. (2001). Stem cells, cancer, and cancer stem cells. Nature, 414, 105-111.
-
(2001)
Nature
, vol.414
, pp. 105-111
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
Weissman, I.L.4
-
160
-
-
33846095137
-
Identifcation and expansion of human colon-cancer-initiating cells
-
Ricci-Vitiani L, Lombardi DG, Pilozzi E, Bifoni M, Todaro M, Peschle C, De Maria R. (2007). Identifcation and expansion of human colon-cancer-initiating cells. Nature, 445, 111-115.
-
(2007)
Nature
, vol.445
, pp. 111-115
-
-
Ricci-Vitiani, L.1
Lombardi, D.G.2
Pilozzi, E.3
Bifoni, M.4
Todaro, M.5
Peschle, C.6
De Maria, R.7
-
161
-
-
78650153633
-
Tumour vascularization via endothelial diferentiation of glioblastoma stem-like cells
-
Ricci-Vitiani L, Pallini R, Bifoni M, Todaro M, Invernici G, Cenci T, Maira G, Parati EA, Stassi G, Larocca LM, De Maria R. (2010). Tumour vascularization via endothelial diferentiation of glioblastoma stem-like cells. Nature, 468, 824-828.
-
(2010)
Nature
, vol.468
, pp. 824-828
-
-
Ricci-Vitiani, L.1
Pallini, R.2
Bifoni, M.3
Todaro, M.4
Invernici, G.5
Cenci, T.6
Maira, G.7
Parati, E.A.8
Stassi, G.9
Larocca, L.M.10
De Maria, R.11
-
162
-
-
0023930539
-
Antibody-directed afnity therapy applied to the immune system: In vivo efectiveness and limited toxicity of daunomycin conjugated to HPMA copolymers and targeting antibody
-
Ríhová B, Kopecková P, Strohalm J, Rossmann P, Vetvicka V, Kopecek J. (1988). Antibody-directed afnity therapy applied to the immune system: in vivo efectiveness and limited toxicity of daunomycin conjugated to HPMA copolymers and targeting antibody. Clin Immunol Immunopathol, 46, 100-114.
-
(1988)
Clin Immunol Immunopathol
, vol.46
, pp. 100-114
-
-
Ríhová, B.1
Kopecková, P.2
Strohalm, J.3
Rossmann, P.4
Vetvicka, V.5
Kopecek, J.6
-
163
-
-
2142809327
-
Immunoprotective therapy with targeted anticancer drugs
-
Ríhová B, Strohalm J, Hoste K, Jelínková M, Hovorka O, Kovár M, Plocová D, Šírová M, Št'astný M, Schacht E, Ulbrich K. (2001). Immunoprotective therapy with targeted anticancer drugs. Macromolecular Symposia, 172, 21-28.
-
(2001)
Macromolecular Symposia
, vol.172
, pp. 21-28
-
-
Ríhová, B.1
Strohalm, J.2
Hoste, K.3
Jelínková, M.4
Hovorka, O.5
Kovár, M.6
Plocová, D.7
Šírová, M.8
Št'astný, M.9
Schacht, E.10
Ulbrich, K.11
-
164
-
-
0031045279
-
Neovasculature induced by vascular endothelial growth factor is fenestrated
-
Roberts WG, Palade GE. (1997). Neovasculature induced by vascular endothelial growth factor is fenestrated. Cancer Res, 57, 765-772.
-
(1997)
Cancer Res
, vol.57
, pp. 765-772
-
-
Roberts, W.G.1
Palade, G.E.2
-
165
-
-
67649939163
-
The increasing complexity of the cancer stem cell paradigm
-
Rosen JM, Jordan CT. (2009). The increasing complexity of the cancer stem cell paradigm. Science, 324, 1670-1673.
-
(2009)
Science
, vol.324
, pp. 1670-1673
-
-
Rosen, J.M.1
Jordan, C.T.2
-
166
-
-
84865189087
-
+ hematologic malignancies: The German Hodgkin Study Group experience
-
+ hematologic malignancies: the German Hodgkin Study Group experience. Blood, 120, 1470-1472.
-
(2012)
Blood
, vol.120
, pp. 1470-1472
-
-
Rothe, A.1
Sasse, S.2
Goergen, H.3
Eichenauer, D.A.4
Lohri, A.5
Jäger, U.6
Bangard, C.7
Böll, B.8
Von Bergwelt Baildon, M.9
Teurich, S.10
Borchmann, P.11
Engert, A.12
-
167
-
-
84864125045
-
Peptides as targeting elements and tissue penetration devices for nanoparticles
-
Ruoslahti E. (2012). Peptides as targeting elements and tissue penetration devices for nanoparticles. Adv Mater, 24, 3747-3756.
-
(2012)
Adv Mater
, vol.24
, pp. 3747-3756
-
-
Ruoslahti, E.1
-
168
-
-
0038271868
-
From latent disseminated cells to overt metastasis: Genetic analysis of systemic breast cancer progression
-
Schmidt-Kittler O, Ragg T, Daskalakis A, Granzow M, Ahr A, Blankenstein TJ, Kaufmann M, Diebold J, Arnholdt H, Muller P, Bischof J, Harich D, Schlimok G, Riethmuller G, Eils R, Klein CA. (2003). From latent disseminated cells to overt metastasis: genetic analysis of systemic breast cancer progression. Proc Natl Acad Sci USA, 100, 7737-7742.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 7737-7742
-
-
Schmidt-Kittler, O.1
Ragg, T.2
Daskalakis, A.3
Granzow, M.4
Ahr, A.5
Blankenstein, T.J.6
Kaufmann, M.7
Diebold, J.8
Arnholdt, H.9
Muller, P.10
Bischof, J.11
Harich, D.12
Schlimok, G.13
Riethmuller, G.14
Eils, R.15
Klein, C.A.16
-
169
-
-
84555178913
-
Treating metastatic cancer with nanotechnology
-
Schroeder A, Heller DA, Winslow MM, Dahlman JE, Pratt GW, Langer R, Jacks T, Anderson DG. (2012). Treating metastatic cancer with nanotechnology. Nat Rev Cancer, 12, 39-50.
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 39-50
-
-
Schroeder, A.1
Heller, D.A.2
Winslow, M.M.3
Dahlman, J.E.4
Pratt, G.W.5
Langer, R.6
Jacks, T.7
Anderson, D.G.8
-
170
-
-
65349125338
-
Targeting angiogenesis-dependent calcifed neoplasms using combined polymer therapeutics
-
Segal E, Pan H, Ofek P, Udagawa T, Kopecková P, Kopecek J, Satchi-Fainaro R. (2009). Targeting angiogenesis-dependent calcifed neoplasms using combined polymer therapeutics. PLoS ONE, 4, e5233.
-
(2009)
PLoS ONE
, vol.4
-
-
Segal, E.1
Pan, H.2
Ofek, P.3
Udagawa, T.4
Kopecková, P.5
Kopecek, J.6
Satchi-Fainaro, R.7
-
171
-
-
0023450012
-
Efect of molecular weight (Mw) of N-(2-hydroxypropyl)methacrylamide copolymers on body distribution and rate of excretion after subcutaneous, intraperitoneal, and intravenous administration to rats
-
Seymour LW, Duncan R, Strohalm J, Kopecek J. (1987). Efect of molecular weight (Mw) of N-(2-hydroxypropyl)methacrylamide copolymers on body distribution and rate of excretion after subcutaneous, intraperitoneal, and intravenous administration to rats. J Biomed Mater Res, 21, 1341-1358.
-
(1987)
J Biomed Mater Res
, vol.21
, pp. 1341-1358
-
-
Seymour, L.W.1
Duncan, R.2
Strohalm, J.3
Kopecek, J.4
-
172
-
-
0029039418
-
Infuence of molecular weight on passive tumour accumulation of a soluble macromolecular drug carrier
-
Seymour LW, Miyamoto Y, Maeda H, Brereton M, Strohalm J, Ulbrich K, Duncan R. (1995). Infuence of molecular weight on passive tumour accumulation of a soluble macromolecular drug carrier. Eur J Cancer, 31A, 766-770.
-
(1995)
Eur J Cancer
, vol.31 A
, pp. 766-770
-
-
Seymour, L.W.1
Miyamoto, Y.2
Maeda, H.3
Brereton, M.4
Strohalm, J.5
Ulbrich, K.6
Duncan, R.7
-
173
-
-
0037087719
-
Hepatic drug targeting: Phase i evaluation of polymer-bound doxorubicin
-
Cancer Research Campaign Phase I/II Clinical Trials committee.
-
Seymour LW, Ferry DR, Anderson D, Hesslewood S, Julyan PJ, Poyner R, Doran J, Young AM, Burtles S, Kerr DJ; Cancer Research Campaign Phase I/II Clinical Trials committee. (2002). Hepatic drug targeting: phase I evaluation of polymer-bound doxorubicin. J Clin Oncol, 20, 1668-1676.
-
(2002)
J Clin Oncol
, vol.20
, pp. 1668-1676
-
-
Seymour, L.W.1
Ferry, D.R.2
Anderson, D.3
Hesslewood, S.4
Julyan, P.J.5
Poyner, R.6
Doran, J.7
Young, A.M.8
Burtles, S.9
Kerr, D.J.10
-
174
-
-
69449096005
-
Heterogeneity in cancer: Cancer stem cells versus clonal evolution
-
Shackleton M, Quintana E, Fearon ER, Morrison SJ. (2009). Heterogeneity in cancer: cancer stem cells versus clonal evolution. Cell, 138, 822-829.
-
(2009)
Cell
, vol.138
, pp. 822-829
-
-
Shackleton, M.1
Quintana, E.2
Fearon, E.R.3
Morrison, S.J.4
-
175
-
-
34848911943
-
Sequential ABL kinase inhibitor therapy selects for compound drug-resistant BCR-ABL mutations with altered oncogenic potency
-
Shah N P, Skaggs BJ, Branford S, Hughes TP, Nicoll JM, Paquette RL, Sawyers CL. (2007). Sequential ABL kinase inhibitor therapy selects for compound drug-resistant BCR-ABL mutations with altered oncogenic potency. J Clin Invest, 117, 2562-2569.
-
(2007)
J Clin Invest
, vol.117
, pp. 2562-2569
-
-
Shah, N.P.1
Skaggs, B.J.2
Branford, S.3
Hughes, T.P.4
Nicoll, J.M.5
Paquette, R.L.6
Sawyers, C.L.7
-
176
-
-
77950809059
-
A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations
-
Sharma SV, Lee DY, Li B, Quinlan MP, Takahashi F, Maheswaran S, McDermott U, Azizian N, Zou L, Fischbach MA, Wong KK, Brandstetter K, Wittner B, Ramaswamy S, Classon M, Settleman J. (2010). A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations. Cell, 141, 69-80.
-
(2010)
Cell
, vol.141
, pp. 69-80
-
-
Sharma, S.V.1
Lee, D.Y.2
Li, B.3
Quinlan, M.P.4
Takahashi, F.5
Maheswaran, S.6
McDermott, U.7
Azizian, N.8
Zou, L.9
Fischbach, M.A.10
Wong, K.K.11
Brandstetter, K.12
Wittner, B.13
Ramaswamy, S.14
Classon, M.15
Settleman, J.16
-
177
-
-
33746836894
-
Targeted therapy of cancer: New prospects for antibodies and immunoconjugates
-
Sharkey RM, Goldenberg DM. (2006). Targeted therapy of cancer: new prospects for antibodies and immunoconjugates. CA Cancer J Clin, 56, 226-243.
-
(2006)
CA Cancer J Clin
, vol.56
, pp. 226-243
-
-
Sharkey, R.M.1
Goldenberg, D.M.2
-
180
-
-
0035145742
-
Biodistribution and antitumour efcacy of long-circulating N-(2-hydroxypropyl)methacrylamide copolymer-doxorubicin conjugates in nude mice
-
Shiah JG, Dvorák M, Kopecková P, Sun Y, Peterson CM, Kopecek J. (2001a). Biodistribution and antitumour efcacy of long-circulating N-(2-hydroxypropyl)methacrylamide copolymer-doxorubicin conjugates in nude mice. Eur J Cancer, 37, 131-139.
-
(2001)
Eur J Cancer
, vol.37
, pp. 131-139
-
-
Shiah, J.G.1
Dvorák, M.2
Kopecková, P.3
Sun, Y.4
Peterson, C.M.5
Kopecek, J.6
-
181
-
-
0035816192
-
Combination chemotherapy and photodynamic therapy of targetable N-(2-hydroxypropyl)methacrylamide copolymer-doxorubicin/mesochlorin e(6)-OV-TL 16 antibody immunoconjugates
-
Shiah JG, Sun Y, Kopecková P, Peterson CM, Straight RC, Kopecek J. (2001b). Combination chemotherapy and photodynamic therapy of targetable N-(2-hydroxypropyl)methacrylamide copolymer-doxorubicin/mesochlorin e(6)-OV-TL 16 antibody immunoconjugates. J Control Release, 74, 249-253.
-
(2001)
J Control Release
, vol.74
, pp. 249-253
-
-
Shiah, J.G.1
Sun, Y.2
Kopecková, P.3
Peterson, C.M.4
Straight, R.C.5
Kopecek, J.6
-
182
-
-
9244241576
-
Identifcation of human brain tumour initiating cells
-
Singh SK, Hawkins C, Clarke ID, Squire JA, Bayani J, Hide T, Henkelman RM, Cusimano MD, Dirks PB. (2004). Identifcation of human brain tumour initiating cells. Nature, 432, 396-401.
-
(2004)
Nature
, vol.432
, pp. 396-401
-
-
Singh, S.K.1
Hawkins, C.2
Clarke, I.D.3
Squire, J.A.4
Bayani, J.5
Hide, T.6
Henkelman, R.M.7
Cusimano, M.D.8
Dirks, P.B.9
-
183
-
-
0032997033
-
Oncolytic, antiarthritic, matrix metalloproteinase inhibitor
-
Sorbera LA, Graul A, Silvestre J, Castañer J. (1999). Oncolytic, antiarthritic, matrix metalloproteinase inhibitor. Drugs Fut, 24, 16.
-
(1999)
Drugs Fut
, vol.24
, pp. 16
-
-
Sorbera, L.A.1
Graul, A.2
Silvestre, J.3
Castañer, J.4
-
184
-
-
84859715721
-
Tumor microenvironment: A main actor in the metastasis process
-
Spano D, Zollo M. (2012). Tumor microenvironment: a main actor in the metastasis process. Clin Exp Metastasis, 29, 381-395.
-
(2012)
Clin Exp Metastasis
, vol.29
, pp. 381-395
-
-
Spano, D.1
Zollo, M.2
-
185
-
-
0032508627
-
Reversal of intrinsic and acquired forms of drug resistance by hyaluronidase treatment of solid tumors
-
St Croix B, Man S, Kerbel RS. (1998). Reversal of intrinsic and acquired forms of drug resistance by hyaluronidase treatment of solid tumors. Cancer Lett, 131, 35-44.
-
(1998)
Cancer Lett
, vol.131
, pp. 35-44
-
-
St Croix, B.1
Man, S.2
Kerbel, R.S.3
-
186
-
-
70749103751
-
Tissue-penetrating delivery of compounds and nanoparticles into tumors
-
Sugahara KN, Teesalu T, Karmali PP, Kotamraju VR, Agemy L, Girard OM, Hanahan D, Mattrey R F, Ruoslahti E. (2009). Tissue-penetrating delivery of compounds and nanoparticles into tumors. Cancer Cell, 16, 510-520.
-
(2009)
Cancer Cell
, vol.16
, pp. 510-520
-
-
Sugahara, K.N.1
Teesalu, T.2
Karmali, P.P.3
Kotamraju, V.R.4
Agemy, L.5
Girard, O.M.6
Hanahan, D.7
Mattrey, R.F.8
Ruoslahti, E.9
-
187
-
-
77952901022
-
Coadministration of a tumor-penetrating peptide enhances the efcacy of cancer drugs
-
Sugahara KN, Teesalu T, Karmali PP, Kotamraju VR, Agemy L, Greenwald DR, Ruoslahti E. (2010). Coadministration of a tumor-penetrating peptide enhances the efcacy of cancer drugs. Science, 328, 1031-1035.
-
(2010)
Science
, vol.328
, pp. 1031-1035
-
-
Sugahara, K.N.1
Teesalu, T.2
Karmali, P.P.3
Kotamraju, V.R.4
Agemy, L.5
Greenwald, D.R.6
Ruoslahti, E.7
-
188
-
-
33644775686
-
Targeting multidrug resistance in cancer
-
Szakács G, Paterson JK, Ludwig JA, Booth-Genthe C, Gottesman MM. (2006). Targeting multidrug resistance in cancer. Nat Rev Drug Discov, 5, 219-234.
-
(2006)
Nat Rev Drug Discov
, vol.5
, pp. 219-234
-
-
Szakács, G.1
Paterson, J.K.2
Ludwig, J.A.3
Booth-Genthe, C.4
Gottesman, M.M.5
-
189
-
-
76749083490
-
Lymphangiogenesis: Molecular mechanisms and future promise
-
Tammela T, Alitalo K. (2010). Lymphangiogenesis: Molecular mechanisms and future promise. Cell, 140, 460-476.
-
(2010)
Cell
, vol.140
, pp. 460-476
-
-
Tammela, T.1
Alitalo, K.2
-
190
-
-
36849083949
-
Cancer stem cell: Target for anti-cancer therapy
-
Tang C, Ang BT, Pervaiz S. (2007). Cancer stem cell: target for anti-cancer therapy. FASEB J, 21, 3777-3785.
-
(2007)
FASEB J
, vol.21
, pp. 3777-3785
-
-
Tang, C.1
Ang, B.T.2
Pervaiz, S.3
-
191
-
-
33847049076
-
Coencapsulation of irinotecan and foxuridine into low cholesterol-containing liposomes that coordinate drug release in vivo
-
Tardi PG, Gallagher RC, Johnstone S, Harasym N, Webb M, Bally MB, Mayer LD. (2007). Coencapsulation of irinotecan and foxuridine into low cholesterol-containing liposomes that coordinate drug release in vivo. Biochim Biophys Acta, 1768, 678-687.
-
(2007)
Biochim Biophys Acta
, vol.1768
, pp. 678-687
-
-
Tardi, P.G.1
Gallagher, R.C.2
Johnstone, S.3
Harasym, N.4
Webb, M.5
Bally, M.B.6
Mayer, L.D.7
-
192
-
-
55049108527
-
In vivo maintenance of synergistic cytarabine:daunorubicin ratios greatly enhances therapeutic efcacy
-
Tardi P, Johnstone S, Harasym N, Xie S, Harasym T, Zisman N, Harvie P, Bermudes D, Mayer L. (2009). In vivo maintenance of synergistic cytarabine:daunorubicin ratios greatly enhances therapeutic efcacy. Leuk Res, 33, 129-139.
-
(2009)
Leuk Res
, vol.33
, pp. 129-139
-
-
Tardi, P.1
Johnstone, S.2
Harasym, N.3
Xie, S.4
Harasym, T.5
Zisman, N.6
Harvie, P.7
Bermudes, D.8
Mayer, L.9
-
193
-
-
80054727258
-
Dextran-coated iron oxide nanoparticles: A versatile platform for targeted molecular imaging, molecular diagnostics, and therapy
-
Tassa C, Shaw SY, Weissleder R. (2011). Dextran-coated iron oxide nanoparticles: a versatile platform for targeted molecular imaging, molecular diagnostics, and therapy. Acc Chem Res, 44, 842-852.
-
(2011)
Acc Chem Res
, vol.44
, pp. 842-852
-
-
Tassa, C.1
Shaw, S.Y.2
Weissleder, R.3
-
194
-
-
84870236985
-
Anticancer nanomedicine and tumor vascular permeability; Where is the missing link?
-
DOI: 10.1016/j.jconrel.2012.07.013
-
Taurin S, Nehof H, Greish K. (2012). Anticancer nanomedicine and tumor vascular permeability; Where is the missing link? J Control Release, DOI: 10.1016/j.jconrel.2012.07.013.
-
(2012)
J Control Release
-
-
Taurin, S.1
Nehof, H.2
Greish, K.3
-
195
-
-
76349104842
-
Wnt/beta-catenin signaling regulates cancer stem cells in lung cancer A549 cells
-
Teng Y, Wang X, Wang Y, Ma D. (2010). Wnt/beta-catenin signaling regulates cancer stem cells in lung cancer A549 cells. Biochem Biophys Res Commun, 392, 373-379.
-
(2010)
Biochem Biophys Res Commun
, vol.392
, pp. 373-379
-
-
Teng, Y.1
Wang, X.2
Wang, Y.3
Ma, D.4
-
196
-
-
0242270878
-
Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis
-
Tayer SP, di Magliano MP, Heiser PW, Nielsen CM, Roberts DJ, Lauwers GY, Qi YP, Gysin S, Fernández-del Castillo C, Yajnik V, Antoniu B, McMahon M, Warshaw AL, Hebrok M. (2003). Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis. Nature, 425, 851-856.
-
(2003)
Nature
, vol.425
, pp. 851-856
-
-
Tayer, S.P.1
Di Magliano, M.P.2
Heiser, P.W.3
Nielsen, C.M.4
Roberts, D.J.5
Lauwers, G.Y.6
Qi, Y.P.7
Gysin, S.8
Fernández-Del Castillo, C.9
Yajnik, V.10
Antoniu, B.11
McMahon, M.12
Warshaw, A.L.13
Hebrok, M.14
-
197
-
-
78649638780
-
Enzymatic depletion of tumor hyaluronan induces antitumor responses in preclinical animal models
-
Tompson CB, Shepard HM, O'Connor PM, Kadhim S, Jiang P, Osgood RJ, Bookbinder LH, Li X, Sugarman BJ, Connor RJ, Nadjsombati S, Frost GI. (2010). Enzymatic depletion of tumor hyaluronan induces antitumor responses in preclinical animal models. Mol Cancer Ter, 9, 3052-3064.
-
(2010)
Mol Cancer ter
, vol.9
, pp. 3052-3064
-
-
Tompson, C.B.1
Shepard, H.M.2
O'Connor, P.M.3
Kadhim, S.4
Jiang, P.5
Osgood, R.J.6
Bookbinder, L.H.7
Li, X.8
Sugarman, B.J.9
Connor, R.J.10
Nadjsombati, S.11
Frost, G.I.12
-
198
-
-
0019430432
-
Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil
-
Tsuruo T, Iida H, Tsukagoshi S, Sakurai Y. (1981). Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil. Cancer Res, 41, 1967-1972.
-
(1981)
Cancer Res
, vol.41
, pp. 1967-1972
-
-
Tsuruo, T.1
Iida, H.2
Tsukagoshi, S.3
Sakurai, Y.4
-
199
-
-
0037458920
-
HPMA copolymers with pH-controlled release of doxorubicin: In vitro cytotoxicity and in vivo antitumor activity
-
Ulbrich K, Etrych T, Chytil P, Jelínková M, Ríhová B. (2003). HPMA copolymers with pH-controlled release of doxorubicin: in vitro cytotoxicity and in vivo antitumor activity. J Control Release, 87, 33-47.
-
(2003)
J Control Release
, vol.87
, pp. 33-47
-
-
Ulbrich, K.1
Etrych, T.2
Chytil, P.3
Jelínková, M.4
Ríhová, B.5
-
200
-
-
75749144204
-
Structural and chemical aspects of HPMA copolymers as drug carriers
-
Ulbrich K, Šubr V. (2010). Structural and chemical aspects of HPMA copolymers as drug carriers. Adv Drug Deliv Rev, 62, 150-166.
-
(2010)
Adv Drug Deliv Rev
, vol.62
, pp. 150-166
-
-
Ulbrich, K.1
Šubr, V.2
-
201
-
-
79957794004
-
Cancer cell invasion: Treatment and monitoring opportunities in nanomedicine
-
Veiseh O, Kievit FM, Ellenbogen RG, Zhang M. (2011). Cancer cell invasion: treatment and monitoring opportunities in nanomedicine. Adv Drug Deliv Rev, 63, 582-596.
-
(2011)
Adv Drug Deliv Rev
, vol.63
, pp. 582-596
-
-
Veiseh, O.1
Kievit, F.M.2
Ellenbogen, R.G.3
Zhang, M.4
-
202
-
-
77956652807
-
Phase II study of NKTR-102 in women with platinum-resistant/refractory ovarian cancer
-
Vergote IB, Micha J P, Pippitt Jr CH, Rao GG, Spitz DL, Reed N, Dark GG, Garcia A, Maslyar DJ, Rustin GJ. (2010). Phase II study of NKTR-102 in women with platinum-resistant/refractory ovarian cancer. J Clin Oncol, 28(15suppl), abstract5013.
-
(2010)
J Clin Oncol
, vol.28
, Issue.15 SUPPL.
-
-
Vergote, I.B.1
Micha, J.P.2
Pippitt Jr., C.H.3
Rao, G.G.4
Spitz, D.L.5
Reed, N.6
Dark, G.G.7
Garcia, A.8
Maslyar, D.J.9
Rustin, G.J.10
-
203
-
-
21244493239
-
Polymer therapeutics designed for a combination therapy of hormone-dependent cancer
-
Vicent MJ, Greco F, Nicholson RI, Paul A, Grifths PC, Duncan R. (2005). Polymer therapeutics designed for a combination therapy of hormone-dependent cancer. Angew Chem Int Ed Engl, 44, 4061-4066.
-
(2005)
Angew Chem Int Ed Engl
, vol.44
, pp. 4061-4066
-
-
Vicent, M.J.1
Greco, F.2
Nicholson, R.I.3
Paul, A.4
Grifths, P.C.5
Duncan, R.6
-
204
-
-
55349098455
-
Targeting melanoma growth and metastasis with systemic delivery of liposome-incorporated protease-activated receptor-1 small interfering RNA
-
Villares GJ, Zigler M, Wang H, Melnikova VO, Wu H, Friedman R, Leslie MC, Vivas-Mejia PE, Lopez-Berestein G, Sood AK, Bar-Eli M. (2008). Targeting melanoma growth and metastasis with systemic delivery of liposome-incorporated protease-activated receptor-1 small interfering RNA. Cancer Res, 68, 9078-9086.
-
(2008)
Cancer Res
, vol.68
, pp. 9078-9086
-
-
Villares, G.J.1
Zigler, M.2
Wang, H.3
Melnikova, V.O.4
Wu, H.5
Friedman, R.6
Leslie, M.C.7
Vivas-Mejia, P.E.8
Lopez-Berestein, G.9
Sood, A.K.10
Bar-Eli, M.11
-
205
-
-
84859450097
-
Cancer stem cells and drug resistance: The potential of nanomedicine
-
Vinogradov S, Wei X. (2012). Cancer stem cells and drug resistance: the potential of nanomedicine. Nanomedicine (Lond), 7, 597-615.
-
(2012)
Nanomedicine (Lond)
, vol.7
, pp. 597-615
-
-
Vinogradov, S.1
Wei, X.2
-
206
-
-
33749820952
-
The emerging nanomedicine landscape
-
Wagner V, Dullaart A, Bock AK, Zweck A. (2006). The emerging nanomedicine landscape. Nat Biotechnol, 24, 1211-1217.
-
(2006)
Nat Biotechnol
, vol.24
, pp. 1211-1217
-
-
Wagner, V.1
Dullaart, A.2
Bock, A.K.3
Zweck, A.4
-
207
-
-
0037268220
-
Paclitaxel at ultra low concentrations inhibits angiogenesis without afecting cellular microtubule assembly
-
Wang J, Lou P, Lesniewski R, Henkin J. (2003). Paclitaxel at ultra low concentrations inhibits angiogenesis without afecting cellular microtubule assembly. Anticancer Drugs, 14, 13-19.
-
(2003)
Anticancer Drugs
, vol.14
, pp. 13-19
-
-
Wang, J.1
Lou, P.2
Lesniewski, R.3
Henkin, J.4
-
208
-
-
78650098659
-
Glioblastoma stem-like cells give rise to tumour endothelium
-
Wang R, Chadalavada K, Wilshire J, Kowalik U, Hovinga KE, Geber A, Fligelman B, Leversha M, Brennan C, Tabar V. (2010). Glioblastoma stem-like cells give rise to tumour endothelium. Nature, 468, 829-833.
-
(2010)
Nature
, vol.468
, pp. 829-833
-
-
Wang, R.1
Chadalavada, K.2
Wilshire, J.3
Kowalik, U.4
Hovinga, K.E.5
Geber, A.6
Fligelman, B.7
Leversha, M.8
Brennan, C.9
Tabar, V.10
-
209
-
-
77957682470
-
Current views on the function of the lymphatic vasculature in health and disease
-
Wang Y, Oliver G. (2010). Current views on the function of the lymphatic vasculature in health and disease. Genes Dev, 24, 2115-2126.
-
(2010)
Genes Dev
, vol.24
, pp. 2115-2126
-
-
Wang, Y.1
Oliver, G.2
-
210
-
-
65549141305
-
Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of the notch signaling pathway
-
Wang Z, Li Y, Kong D, Banerjee S, Ahmad A, Azmi AS, Ali S, Abbruzzese JL, Gallick GE, Sarkar FH. (2009). Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of the notch signaling pathway. Cancer Res, 69, 2400-2407.
-
(2009)
Cancer Res
, vol.69
, pp. 2400-2407
-
-
Wang, Z.1
Li, Y.2
Kong, D.3
Banerjee, S.4
Ahmad, A.5
Azmi, A.S.6
Ali, S.7
Abbruzzese, J.L.8
Gallick, G.E.9
Sarkar, F.H.10
-
211
-
-
79952771880
-
Revisiting the concept of cancer stem cells in prostate cancer
-
Wang ZA, Shen MM. (2011). Revisiting the concept of cancer stem cells in prostate cancer. Oncogene, 30, 1261-1271.
-
(2011)
Oncogene
, vol.30
, pp. 1261-1271
-
-
Wang, Z.A.1
Shen, M.M.2
-
212
-
-
0032748607
-
Radioimmunotherapy of relapsed non-Hodgkin's lymphoma with zevalin, a 90Y-labeled anti-CD20 monoclonal antibody
-
Wiseman GA, White CA, Witzig TE, Gordon LI, Emmanouilides C, Raubitschek A, Janakiraman N, Gutheil J, Schilder RJ, Spies S, Silverman DH, Grillo-López AJ. (1999). Radioimmunotherapy of relapsed non-Hodgkin's lymphoma with zevalin, a 90Y-labeled anti-CD20 monoclonal antibody. Clin Cancer Res, 5, 3281s-3286s.
-
(1999)
Clin Cancer Res
, vol.5
-
-
Wiseman, G.A.1
White, C.A.2
Witzig, T.E.3
Gordon, L.I.4
Emmanouilides, C.5
Raubitschek, A.6
Janakiraman, N.7
Gutheil, J.8
Schilder, R.J.9
Spies, S.10
Silverman, D.H.11
Grillo-López, A.J.12
-
213
-
-
0037455576
-
Compensation mechanism in tumor cell migration: Mesenchymal-amoeboid transition after blocking of pericellular proteolysis
-
Wolf K, Mazo I, Leung H, Engelke K, von Andrian UH, Deryugina EI, Strongin AY, Bröcker EB, Friedl P. (2003). Compensation mechanism in tumor cell migration: mesenchymal-amoeboid transition after blocking of pericellular proteolysis. J Cell Biol, 160, 267-277.
-
(2003)
J Cell Biol
, vol.160
, pp. 267-277
-
-
Wolf, K.1
Mazo, I.2
Leung, H.3
Engelke, K.4
Von Andrian, U.H.5
Deryugina, E.I.6
Strongin, A.Y.7
Bröcker, E.B.8
Friedl, P.9
-
214
-
-
34547569807
-
Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion
-
Wolf K, Wu YI, Liu Y, Geiger J, Tam E, Overall C, Stack MS, Friedl P. (2007). Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion. Nat Cell Biol, 9, 893-904.
-
(2007)
Nat Cell Biol
, vol.9
, pp. 893-904
-
-
Wolf, K.1
Wu, Y.I.2
Liu, Y.3
Geiger, J.4
Tam, E.5
Overall, C.6
Stack, M.S.7
Friedl, P.8
-
215
-
-
0031964923
-
Modulation of enhanced vascular permeability in tumors by a bradykinin antagonist, a cyclooxygenase inhibitor, and a nitric oxide scavenger
-
Wu J, Akaike T, Maeda H. (1998). Modulation of enhanced vascular permeability in tumors by a bradykinin antagonist, a cyclooxygenase inhibitor, and a nitric oxide scavenger. Cancer Res, 58, 159-165.
-
(1998)
Cancer Res
, vol.58
, pp. 159-165
-
-
Wu, J.1
Akaike, T.2
Maeda, H.3
-
216
-
-
76649140507
-
Drug-free macromolecular therapeutics: Induction of apoptosis by coiled-coil-mediated cross-linking of antigens on the cell surface
-
Wu K, Liu J, Johnson RN, Yang J, Kopecek J. (2010). Drug-free macromolecular therapeutics: induction of apoptosis by coiled-coil-mediated cross-linking of antigens on the cell surface. Angew Chem Int Ed Engl, 49, 1451-1455.
-
(2010)
Angew Chem Int Ed Engl
, vol.49
, pp. 1451-1455
-
-
Wu, K.1
Liu, J.2
Johnson, R.N.3
Yang, J.4
Kopecek, J.5
-
217
-
-
84855852603
-
Coiled-coil based drug-free macromolecular therapeutics: In vivo efcacy
-
Wu K, Yang J, Liu J, Kopecek J. (2012). Coiled-coil based drug-free macromolecular therapeutics: In vivo efcacy. J Control Release, 157, 126-131.
-
(2012)
J Control Release
, vol.157
, pp. 126-131
-
-
Wu, K.1
Yang, J.2
Liu, J.3
Kopecek, J.4
-
218
-
-
84855858432
-
LyP-1-conjugated PEGylated liposomes: A carrier system for targeted therapy of lymphatic metastatic tumor
-
Yan Z, Wang F, Wen Z, Zhan C, Feng L, Liu Y, Wei X, Xie C, Lu W. (2012). LyP-1-conjugated PEGylated liposomes: A carrier system for targeted therapy of lymphatic metastatic tumor. J Control Release, 157, 118-125.
-
(2012)
J Control Release
, vol.157
, pp. 118-125
-
-
Yan, Z.1
Wang, F.2
Wen, Z.3
Zhan, C.4
Feng, L.5
Liu, Y.6
Wei, X.7
Xie, C.8
Lu, W.9
-
219
-
-
80053230454
-
LyP-1-conjugated doxorubicin-loaded liposomes suppress lymphatic metastasis by inhibiting lymph node metastases and destroying tumor lymphatics
-
Yan Z, Zhan C, Wen Z, Feng L, Wang F, Liu Y, Yang X, Dong Q, Liu M, Lu W. (2011). LyP-1-conjugated doxorubicin-loaded liposomes suppress lymphatic metastasis by inhibiting lymph node metastases and destroying tumor lymphatics. Nanotechnology, 22, 415103.
-
(2011)
Nanotechnology
, vol.22
, pp. 415103
-
-
Yan, Z.1
Zhan, C.2
Wen, Z.3
Feng, L.4
Wang, F.5
Liu, Y.6
Yang, X.7
Dong, Q.8
Liu, M.9
Lu, W.10
-
220
-
-
44449144396
-
Epithelial-mesenchymal transition: At the crossroads of development and tumor metastasis
-
Yang J, Weinberg RA. (2008). Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis. Dev Cell, 14, 818-829.
-
(2008)
Dev Cell
, vol.14
, pp. 818-829
-
-
Yang, J.1
Weinberg, R.A.2
-
221
-
-
79551684989
-
Synthesis of biodegradable multiblock copolymers by click coupling of RAFT-generated heterotelechelicpolyHPMA conjugates
-
Yang J, Luo K, Pan H, Kopecková P, Kopecek J. (2011). Synthesis of Biodegradable Multiblock Copolymers by Click Coupling of RAFT-Generated HeterotelechelicPolyHPMA Conjugates. React Funct Polym, 71, 294-302.
-
(2011)
React Funct Polym
, vol.71
, pp. 294-302
-
-
Yang, J.1
Luo, K.2
Pan, H.3
Kopecková, P.4
Kopecek, J.5
-
222
-
-
33646376411
-
Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells
-
Yilmaz OH, Valdez R, Teisen BK, Guo W, Ferguson DO, Wu H, Morrison SJ. (2006). Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells. Nature, 441, 475-482.
-
(2006)
Nature
, vol.441
, pp. 475-482
-
-
Yilmaz, O.H.1
Valdez, R.2
Teisen, B.K.3
Guo, W.4
Ferguson, D.O.5
Wu, H.6
Morrison, S.J.7
-
223
-
-
0029150245
-
Vascular permeability in a human tumor xenograft: Molecular size dependence and cutof size
-
Yuan F, Dellian M, Fukumura D, Leunig M, Berk DA, Torchilin VP, Jain RK. (1995). Vascular permeability in a human tumor xenograft: molecular size dependence and cutof size. Cancer Res, 55, 3752-3756.
-
(1995)
Cancer Res
, vol.55
, pp. 3752-3756
-
-
Yuan, F.1
Dellian, M.2
Fukumura, D.3
Leunig, M.4
Berk, D.A.5
Torchilin, V.P.6
Jain, R.K.7
-
224
-
-
0028025011
-
Vascular permeability and microcirculation of gliomas and mammary carcinomas transplanted in rat and mouse cranial windows
-
Yuan F, Salehi HA, Boucher Y, Vasthare US, Tuma RF, Jain RK. (1994). Vascular permeability and microcirculation of gliomas and mammary carcinomas transplanted in rat and mouse cranial windows. Cancer Res, 54, 4564-4568.
-
(1994)
Cancer Res
, vol.54
, pp. 4564-4568
-
-
Yuan, F.1
Salehi, H.A.2
Boucher, Y.3
Vasthare, U.S.4
Tuma, R.F.5
Jain, R.K.6
-
225
-
-
36849078711
-
Let-7 regulates self renewal and tumorigenicity of breast cancer cells
-
Yu F, Yao H, Zhu P, Zhang X, Pan Q, Gong C, Huang Y, Hu X, Su F, Lieberman J, Song E. (2007). let-7 regulates self renewal and tumorigenicity of breast cancer cells. Cell, 131, 1109-1123.
-
(2007)
Cell
, vol.131
, pp. 1109-1123
-
-
Yu, F.1
Yao, H.2
Zhu, P.3
Zhang, X.4
Pan, Q.5
Gong, C.6
Huang, Y.7
Hu, X.8
Su, F.9
Lieberman, J.10
Song, E.11
-
226
-
-
33646351002
-
PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention
-
Zhang J, Grindley JC, Yin T, Jayasinghe S, He XC, Ross JT, Haug JS, Rupp D, Porter-Westpfahl KS, Wiedemann LM, Wu H, Li L. (2006). PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention. Nature, 441, 518-522.
-
(2006)
Nature
, vol.441
, pp. 518-522
-
-
Zhang, J.1
Grindley, J.C.2
Yin, T.3
Jayasinghe, S.4
He, X.C.5
Ross, J.T.6
Haug, J.S.7
Rupp, D.8
Porter-Westpfahl, K.S.9
Wiedemann, L.M.10
Wu, H.11
Li, L.12
-
227
-
-
83555176260
-
Selective inhibitory efect of HPMA copolymer-cyclopamine conjugate on prostate cancer stem cells
-
Zhou Y, Yang J, Kopecek J. (2012). Selective inhibitory efect of HPMA copolymer-cyclopamine conjugate on prostate cancer stem cells. Biomaterials, 33, 1863-1872.
-
(2012)
Biomaterials
, vol.33
, pp. 1863-1872
-
-
Zhou, Y.1
Yang, J.2
Kopecek, J.3
|