Targetable HPMA copolymer-adriamycin conjugates. Recognition, internalization, and subcellular fate

Journal of Controlled Release

Volumn 53, Issue 1-3, 1998, Pages 25-37

  Omelyanenko, V ^a   Kopeckova P ^a   Gentry, C ^a   Kopecek J ^a  

^a UNIVERSITY OF UTAH   (United States)

Author keywords

Confocal microscopy; Drug release; HPMA copolymer; Subcellular trafficking

Indexed keywords

DOXORUBICIN; FLUORESCEIN ISOTHIOCYANATE; GALACTOSAMINE; MONOCLONAL ANTIBODY; N (2 HYDROXYPROPYL)METHACRYLAMIDE COPOLYMER; TETRAPEPTIDE;

CELL NUCLEUS; CONFERENCE PAPER; CONTROLLED STUDY; CYTOPLASM; DIFFUSION; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG TARGETING; DRUG TRANSPORT; FLUORESCENCE MICROSCOPY; FLUORESCENCE SPECTROSCOPY; HUMAN; HUMAN CELL; INTERNALIZATION; INTRACELLULAR TRANSPORT; LIVER CELL CARCINOMA; LYSOSOME; MULTIDRUG RESISTANCE; OVARY CARCINOMA; PRIORITY JOURNAL;

ACYLATION; AMINO ACID SEQUENCE; ANIMALS; DOXORUBICIN; DRUG CARRIERS; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; ENDOCYTOSIS; GALACTOSAMINE; HUMANS; MICE; MICE, INBRED BALB C; MICROSCOPY, CONFOCAL; MOLECULAR STRUCTURE; P-GLYCOPROTEIN; POLYMETHACRYLIC ACIDS; SPECTROMETRY, FLUORESCENCE; SUBCELLULAR FRACTIONS; TUMOR CELLS, CULTURED;

EID: 0032580444     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(97)00235-6     Document Type: Conference Paper

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