-
1
-
-
41349099104
-
Cancer statistics, 2008
-
Jemal, A. et al. Cancer statistics, 2008. CA Cancer J. Clin. 58, 71-96 (2008).
-
(2008)
CA Cancer J. Clin
, vol.58
, pp. 71-96
-
-
Jemal, A.1
-
2
-
-
2942603264
-
Tyrosine kinase inhibitors: Why does the current process of clinical development not apply to them?
-
Arteaga, C. L. & Baselga, J. Tyrosine kinase inhibitors: why does the current process of clinical development not apply to them? Cancer Cell 5, 525-531 (2004).
-
(2004)
Cancer Cell
, vol.5
, pp. 525-531
-
-
Arteaga, C.L.1
Baselga, J.2
-
3
-
-
26844503270
-
Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer
-
Piccart-Gebhart, M. J. et al. Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer. N. Engl. J. Med. 353, 1659-1672 (2005).
-
(2005)
N. Engl. J. Med
, vol.353
, pp. 1659-1672
-
-
Piccart-Gebhart, M.J.1
-
4
-
-
26844536978
-
Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer
-
Romond, E. H. et al. Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer. N. Engl. J. Med. 353, 1673-1684 (2005).
-
(2005)
N. Engl. J. Med
, vol.353
, pp. 1673-1684
-
-
Romond, E.H.1
-
5
-
-
33746961739
-
-
Weinstein, I. B. & Joe, A. K. Mechanisms of disease: Oncogene addiction - a rationale for molecular targeting in cancer therapy. Nature Clin. Pract Oncol. 3, 448-457 (2006).
-
Weinstein, I. B. & Joe, A. K. Mechanisms of disease: Oncogene addiction - a rationale for molecular targeting in cancer therapy. Nature Clin. Pract Oncol. 3, 448-457 (2006).
-
-
-
-
6
-
-
0030852491
-
Foulds' dangerous idea revisited: The multistep development of tumors 40 years later
-
Klein, G. Foulds' dangerous idea revisited: the multistep development of tumors 40 years later. Adv. Cancer Res. 72, 1-23 (1998).
-
(1998)
Adv. Cancer Res
, vol.72
, pp. 1-23
-
-
Klein, G.1
-
7
-
-
0025312728
-
A genetic model for colorectal tumorigenesis
-
Fearon, E. R. & Vogelstein, B. A genetic model for colorectal tumorigenesis. Cell 61, 759-767 (1990).
-
(1990)
Cell
, vol.61
, pp. 759-767
-
-
Fearon, E.R.1
Vogelstein, B.2
-
8
-
-
0016692602
-
Mutation selection and the natural history of cancer
-
Cairns, J. Mutation selection and the natural history of cancer. Nature 255, 197-200 (1975).
-
(1975)
Nature
, vol.255
, pp. 197-200
-
-
Cairns, J.1
-
9
-
-
33644772215
-
The clinical value of somatic TP53 gene mutations in 1,794 patients with breast cancer
-
Olivier, M. et al. The clinical value of somatic TP53 gene mutations in 1,794 patients with breast cancer. Clin. Cancer Res. 12, 1157-1167 (2006).
-
(2006)
Clin. Cancer Res
, vol.12
, pp. 1157-1167
-
-
Olivier, M.1
-
10
-
-
52049093659
-
The many faces of tumor dormancy
-
Weinberg, R. A. The many faces of tumor dormancy. APMIS 116, 548-551 (2008).
-
(2008)
APMIS
, vol.116
, pp. 548-551
-
-
Weinberg, R.A.1
-
11
-
-
0016700358
-
Do generalized metastases occur directly from the primary?
-
Bross, I. D., Viadana, E. & Pickren, J. Do generalized metastases occur directly from the primary? J. Chronic Dis. 28, 149-159 (1975).
-
(1975)
J. Chronic Dis
, vol.28
, pp. 149-159
-
-
Bross, I.D.1
Viadana, E.2
Pickren, J.3
-
12
-
-
46949102805
-
Mechanisms of malignant progression
-
Weinberg, R. A. Mechanisms of malignant progression. Carcinogenesis 29, 1092-1095 (2008).
-
(2008)
Carcinogenesis
, vol.29
, pp. 1092-1095
-
-
Weinberg, R.A.1
-
13
-
-
77049278920
-
Observations on growth rates of human tumors
-
Collins, V. P., Loeffler, R. K. & Tivey, H. Observations on growth rates of human tumors. Am. J. Roentgenol. Radium Ther. Nucl. Med. 76, 988-1000 (1956).
-
(1956)
Am. J. Roentgenol. Radium Ther. Nucl. Med
, vol.76
, pp. 988-1000
-
-
Collins, V.P.1
Loeffler, R.K.2
Tivey, H.3
-
14
-
-
0030872642
-
On the growth rates of human malignant tumors: Implications for medical decision making
-
Friberg, S. & Mattson, S. On the growth rates of human malignant tumors: implications for medical decision making. J. Surg. Oncol. 65, 284-297 (1997).
-
(1997)
J. Surg. Oncol
, vol.65
, pp. 284-297
-
-
Friberg, S.1
Mattson, S.2
-
15
-
-
45149134667
-
The staging of cancer: A retrospective and prospective appraisal
-
Greene, F. L. & Sobin, L. H. The staging of cancer: a retrospective and prospective appraisal. CA Cancer J. Clin. 58, 180-190 (2008).
-
(2008)
CA Cancer J. Clin
, vol.58
, pp. 180-190
-
-
Greene, F.L.1
Sobin, L.H.2
-
16
-
-
34548192060
-
The lethal phenotype of cancer: The molecular basis of death due to malignancy
-
Loberg, R. D., Bradley, D. A., Tomlins, S. A., Chinnaiyan, A. M. & Pienta, K. J. The lethal phenotype of cancer: the molecular basis of death due to malignancy. CA Cancer J. Clin. 57, 225-241 (2007).
-
(2007)
CA Cancer J. Clin
, vol.57
, pp. 225-241
-
-
Loberg, R.D.1
Bradley, D.A.2
Tomlins, S.A.3
Chinnaiyan, A.M.4
Pienta, K.J.5
-
17
-
-
0030046467
-
Rates of growth of human neoplasms: Part II
-
Spratt, J. S., Meyer, J. S. & Spratt, J. A. Rates of growth of human neoplasms: Part II. J. Surg. Oncol. 61, 68-83 (1996).
-
(1996)
J. Surg. Oncol
, vol.61
, pp. 68-83
-
-
Spratt, J.S.1
Meyer, J.S.2
Spratt, J.A.3
-
18
-
-
0000221170
-
Rates of growth of pulmonary metastases and host survival
-
Spratt, J. S. Jr & Spratt, T. L. Rates of growth of pulmonary metastases and host survival. Ann. Surg. 159, 161-171 (1964).
-
(1964)
Ann. Surg
, vol.159
, pp. 161-171
-
-
Spratt, J.S.J.1
Spratt, T.L.2
-
19
-
-
0015386298
-
The gross rates of growth of human mammary carcinoma
-
Kusama, S., Spratt, J. S. Jr, Donegan, W. L., Watson, F. R. & Cunningham, C. The gross rates of growth of human mammary carcinoma. Cancer 30, 594-599 (1972).
-
(1972)
Cancer
, vol.30
, pp. 594-599
-
-
Kusama, S.1
Spratt Jr, J.S.2
Donegan, W.L.3
Watson, F.R.4
Cunningham, C.5
-
20
-
-
0023759567
-
Growth rate of hepatic metastases in colorectal carcinoma
-
Finlay, I. G., Meek, D., Brunton, F. & McArdle, C. S. Growth rate of hepatic metastases in colorectal carcinoma. Br. J. Surg. 75, 641-644 (1988).
-
(1988)
Br. J. Surg
, vol.75
, pp. 641-644
-
-
Finlay, I.G.1
Meek, D.2
Brunton, F.3
McArdle, C.S.4
-
21
-
-
0027281405
-
Age-dependent growth rate of primary breast cancer
-
Peer, P. G., van Dijck, J. A., Hendriks, J. H., Holland, R. & Verbeek, A. L. Age-dependent growth rate of primary breast cancer. Cancer 71, 3547-3551 (1993).
-
(1993)
Cancer
, vol.71
, pp. 3547-3551
-
-
Peer, P.G.1
van Dijck, J.A.2
Hendriks, J.H.3
Holland, R.4
Verbeek, A.L.5
-
22
-
-
0041346024
-
The process of metastasisation for breast cancer
-
Engel, J. et al. The process of metastasisation for breast cancer. Eur. J. Cancer 39, 1794-1806 (2003).
-
(2003)
Eur. J. Cancer
, vol.39
, pp. 1794-1806
-
-
Engel, J.1
-
23
-
-
63049099009
-
Metastasierung beim kolorektalen Karzinom: Häufigkeiten, Prognose und Folgerungen
-
28 Sep, epub ahead of print, in German
-
Holzel, D., Eckel, R. & Engel, J. Metastasierung beim kolorektalen Karzinom: Häufigkeiten, Prognose und Folgerungen. Chirurg. 28 Sep 2008 [epub ahead of print] (in German).
-
(2008)
Chirurg
-
-
Holzel, D.1
Eckel, R.2
Engel, J.3
-
24
-
-
0028241857
-
Unknown primary carcinoma: Natural history and prognostic factors in 657 consecutive patients
-
Abbruzzese, J. L. et al. Unknown primary carcinoma: natural history and prognostic factors in 657 consecutive patients. J. Clin. Oncol. 12, 1272-1280 (1994).
-
(1994)
J. Clin. Oncol
, vol.12
, pp. 1272-1280
-
-
Abbruzzese, J.L.1
-
25
-
-
0036161957
-
Epidemiology of unknown primary tumours; incidence and population-based survival of 1285 patients in Southeast Netherlands, 1984-1992
-
van de Wouw, A. J., Janssen-Heijnen, M. L., Coebergh, J. W. & Hillen, H. F. Epidemiology of unknown primary tumours; incidence and population-based survival of 1285 patients in Southeast Netherlands, 1984-1992 Eur. J. Cancer 38, 409-413 (2002).
-
(2002)
Eur. J. Cancer
, vol.38
, pp. 409-413
-
-
van de Wouw, A.J.1
Janssen-Heijnen, M.L.2
Coebergh, J.W.3
Hillen, H.F.4
-
26
-
-
28644432204
-
VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche
-
Kaplan, R. N. et al. VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche. Nature 438, 820-827 (2005).
-
(2005)
Nature
, vol.438
, pp. 820-827
-
-
Kaplan, R.N.1
-
27
-
-
44649088833
-
Systemic endocrine instigation of indolent tumor growth requires osteopontin
-
McAllister, S. S. et al. Systemic endocrine instigation of indolent tumor growth requires osteopontin. Cell 133, 994-1005 (2008).
-
(2008)
Cell
, vol.133
, pp. 994-1005
-
-
McAllister, S.S.1
-
28
-
-
0029131392
-
Serum concentrations of hepatocyte growth factor in breast cancer patients
-
Taniguchi, T. et al. Serum concentrations of hepatocyte growth factor in breast cancer patients. Clin. Cancer Res. 1, 1031-1034 (1995).
-
(1995)
Clin. Cancer Res
, vol.1
, pp. 1031-1034
-
-
Taniguchi, T.1
-
29
-
-
0342507974
-
Micrometastatic cancer cells in bone marrow: In vitro detection with anti-cytokeratin and in vivo labeling with anti-17-1A monoclonal antibodies
-
Schlimok, G. et al. Micrometastatic cancer cells in bone marrow: in vitro detection with anti-cytokeratin and in vivo labeling with anti-17-1A monoclonal antibodies. Proc. Natl Acad. Sci. USA 84, 8672-8676 (1987).
-
(1987)
Proc. Natl Acad. Sci. USA
, vol.84
, pp. 8672-8676
-
-
Schlimok, G.1
-
30
-
-
0642337591
-
The systemic progression of human cancer: A focus on the individual disseminated cancer cell - the unit of selection
-
Klein, C. A. The systemic progression of human cancer: a focus on the individual disseminated cancer cell - the unit of selection. Adv. Cancer Res. 89, 35-67 (2003).
-
(2003)
Adv. Cancer Res
, vol.89
, pp. 35-67
-
-
Klein, C.A.1
-
31
-
-
0033532955
-
Detection and clinical importance of micrometastatic disease
-
Pantel, K., Cote, R. J. & Fodstad, O. Detection and clinical importance of micrometastatic disease. J. Natl Cancer Inst. 91, 1113-1124 (1999).
-
(1999)
J. Natl Cancer Inst
, vol.91
, pp. 1113-1124
-
-
Pantel, K.1
Cote, R.J.2
Fodstad, O.3
-
32
-
-
33747893501
-
A concept for the standardized detection of disseminated tumor cells in bone marrow from patients with primary breast cancer and its clinical implementation
-
Fehm, T. et al. A concept for the standardized detection of disseminated tumor cells in bone marrow from patients with primary breast cancer and its clinical implementation. Cancer 107, 885-892 (2006).
-
(2006)
Cancer
, vol.107
, pp. 885-892
-
-
Fehm, T.1
-
33
-
-
51649120140
-
Biological relevance of disseminated tumor cells in cancer patients
-
Riethdorf, S., Wikman, H. & Pantel, K. Biological relevance of disseminated tumor cells in cancer patients. Int. J. Cancer 123, 1991-2006 (2008).
-
(2008)
Int. J. Cancer
, vol.123
, pp. 1991-2006
-
-
Riethdorf, S.1
Wikman, H.2
Pantel, K.3
-
34
-
-
0033551238
-
Comparative genomic hybridization, loss of heterozygosity, and DNA sequence analysis of single cells
-
Klein, C. A. et al. Comparative genomic hybridization, loss of heterozygosity, and DNA sequence analysis of single cells. Proc. Natl Acad. Sci. USA 96, 4494-4499 (1999).
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 4494-4499
-
-
Klein, C.A.1
-
35
-
-
18344382135
-
Combined transcriptome and genome analysis of single micrometastatic cells
-
Klein, C. A. et al. Combined transcriptome and genome analysis of single micrometastatic cells. Nature Biotechnol. 20, 387-392 (2002).
-
(2002)
Nature Biotechnol
, vol.20
, pp. 387-392
-
-
Klein, C.A.1
-
36
-
-
24944534497
-
Genomic analysis of single cytokeratin-positive cells from bone marrow reveals early mutational events in breast cancer
-
Schardt, J. A. et al. Genomic analysis of single cytokeratin-positive cells from bone marrow reveals early mutational events in breast cancer. Cancer Cell 8, 227-239 (2005).
-
(2005)
Cancer Cell
, vol.8
, pp. 227-239
-
-
Schardt, J.A.1
-
37
-
-
0038271868
-
From latent disseminated cells to overt metastasis: Genetic analysis of systemic breast cancer progression
-
Schmidt-Kittler, O. et al. From latent disseminated cells to overt metastasis: genetic analysis of systemic breast cancer progression. Proc. Natl Acad. Sci. USA 100, 7737-7742 (2003).
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 7737-7742
-
-
Schmidt-Kittler, O.1
-
38
-
-
42949150219
-
Direct genetic analysis of single disseminated cancer cells for prediction of outcome and therapy selection in esophageal cancer
-
Stoecklein, N. H. et al. Direct genetic analysis of single disseminated cancer cells for prediction of outcome and therapy selection in esophageal cancer. Cancer Cell 13, 441-453 (2008).
-
(2008)
Cancer Cell
, vol.13
, pp. 441-453
-
-
Stoecklein, N.H.1
-
39
-
-
63749083366
-
Perioperative activation of disseminated tumor cells in bone marrow of patients with prostate cancer
-
23 Feb, doi:10.1200/JCO.2008.17.0563
-
Weckermann, D. et al. Perioperative activation of disseminated tumor cells in bone marrow of patients with prostate cancer. J. Clin. Oncol. 23 Feb 2009 (doi:10.1200/JCO.2008.17.0563).
-
(2009)
J. Clin. Oncol
-
-
Weckermann, D.1
-
40
-
-
0037206022
-
Genetic heterogeneity of single disseminated tumour cells in minimal residual cancer
-
Klein, C. A. et al. Genetic heterogeneity of single disseminated tumour cells in minimal residual cancer. Lancet 360, 683-689 (2002).
-
(2002)
Lancet
, vol.360
, pp. 683-689
-
-
Klein, C.A.1
-
41
-
-
8444220804
-
Heterogeneity within and between primary colorectal carcinomas and matched metastases as revealed by analysis of Ki-ras and p53 mutations
-
Albanese, I. et al. Heterogeneity within and between primary colorectal carcinomas and matched metastases as revealed by analysis of Ki-ras and p53 mutations. Biochem. Biophys. Res. Commun. 325, 784-791 (2004).
-
(2004)
Biochem. Biophys. Res. Commun
, vol.325
, pp. 784-791
-
-
Albanese, I.1
-
42
-
-
51649084560
-
Mutations of KRAS and BRAF in primary and matched metastatic sites of colorectal cancer
-
Artale, S. et al. Mutations of KRAS and BRAF in primary and matched metastatic sites of colorectal cancer. J. Clin. Oncol. 26, 4217-4219 (2008).
-
(2008)
J. Clin. Oncol
, vol.26
, pp. 4217-4219
-
-
Artale, S.1
-
43
-
-
0025889018
-
Differential activation of ras genes by point mutation in human colon cancer with metastases to either lung or liver
-
Oudejans, J. J., Slebos, R. J., Zoetmulder, F. A., Mooi, W. J. & Rodenhuis, S. Differential activation of ras genes by point mutation in human colon cancer with metastases to either lung or liver. Int. J. Cancer 49, 875-879 (1991).
-
(1991)
Int. J. Cancer
, vol.49
, pp. 875-879
-
-
Oudejans, J.J.1
Slebos, R.J.2
Zoetmulder, F.A.3
Mooi, W.J.4
Rodenhuis, S.5
-
44
-
-
34547616992
-
Phenotype of bone metastases of non-small cell lung cancer: Epidermal growth factor receptor expression and K-RAS mutational status
-
Badalian, G. et al. Phenotype of bone metastases of non-small cell lung cancer: epidermal growth factor receptor expression and K-RAS mutational status. Pathol. Oncol. Res. 13, 99-104 (2007).
-
(2007)
Pathol. Oncol. Res
, vol.13
, pp. 99-104
-
-
Badalian, G.1
-
45
-
-
51449101924
-
Comparison of EGFR and K-RAS gene status between primary tumours and corresponding metastases in NSCLC
-
Kalikaki, A. et al. Comparison of EGFR and K-RAS gene status between primary tumours and corresponding metastases in NSCLC. Br. J. Cancer 99, 923-929 (2008).
-
(2008)
Br. J. Cancer
, vol.99
, pp. 923-929
-
-
Kalikaki, A.1
-
46
-
-
63549140887
-
Comparison of epidermal growth factor receptor mutations between primary and corresponding metastatic tumors in tyrosine kinase inhibitor-naive non-small-cell lung cancer
-
16 Dec, doi:10.1093/annonc/mdn679
-
Gow, C. H. et al. Comparison of epidermal growth factor receptor mutations between primary and corresponding metastatic tumors in tyrosine kinase inhibitor-naive non-small-cell lung cancer. Ann. Oncol. 16 Dec 2008 (doi:10.1093/annonc/mdn679).
-
(2008)
Ann. Oncol
-
-
Gow, C.H.1
-
47
-
-
40549095285
-
The genomic heritage of lymph node metastases: Implications for clinical management of patients with breast cancer
-
Becker, T. E. et al. The genomic heritage of lymph node metastases: implications for clinical management of patients with breast cancer. Ann. Surg. Oncol. 15, 1056-1063 (2008).
-
(2008)
Ann. Surg. Oncol
, vol.15
, pp. 1056-1063
-
-
Becker, T.E.1
-
48
-
-
0033031878
-
Evaluation of the clonal relationship between primary and metastatic renal cell carcinoma by comparative genomic hybridization
-
Bissig, H. et al. Evaluation of the clonal relationship between primary and metastatic renal cell carcinoma by comparative genomic hybridization. Am. J. Pathol. 155, 267-274 (1999).
-
(1999)
Am. J. Pathol
, vol.155
, pp. 267-274
-
-
Bissig, H.1
-
49
-
-
0342887306
-
Genetic heterogeneity and clonal evolution underlying development of asynchronous metastasis in human breast cancer
-
Kuukasjarvi, T. et al. Genetic heterogeneity and clonal evolution underlying development of asynchronous metastasis in human breast cancer. Cancer Res. 57, 1597-1604 (1997).
-
(1997)
Cancer Res
, vol.57
, pp. 1597-1604
-
-
Kuukasjarvi, T.1
-
50
-
-
34347355444
-
Genetically heterogeneous and clonally unrelated metastases may arise in patients with cutaneous melanoma
-
Katona, T. M. et al. Genetically heterogeneous and clonally unrelated metastases may arise in patients with cutaneous melanoma. Am. J. Surg. Pathol. 31, 1029-1037 (2007).
-
(2007)
Am. J. Surg. Pathol
, vol.31
, pp. 1029-1037
-
-
Katona, T.M.1
-
51
-
-
41949139438
-
Comparative lesion sequencing provides insights into tumor evolution
-
Jones, S. et al. Comparative lesion sequencing provides insights into tumor evolution. Proc. Natl Acad. Sci. USA 105, 4283-4288 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 4283-4288
-
-
Jones, S.1
-
52
-
-
0346734120
-
Gene expression profiles of primary breast tumors maintained in distant metastases
-
Weigelt, B. et al. Gene expression profiles of primary breast tumors maintained in distant metastases. Proc. Natl Acad. Sci. USA 100, 15901-15905 (2003).
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 15901-15905
-
-
Weigelt, B.1
-
53
-
-
33644844519
-
Host genetics influence tumour metastasis
-
Hunter, K. Host genetics influence tumour metastasis. Nature Rev. Cancer 6, 141-146 (2006).
-
(2006)
Nature Rev. Cancer
, vol.6
, pp. 141-146
-
-
Hunter, K.1
-
54
-
-
37349079197
-
Systemic spread is an early step in breast cancer
-
Husemann, Y. et al. Systemic spread is an early step in breast cancer. Cancer Cell 13, 58-68 (2008).
-
(2008)
Cancer Cell
, vol.13
, pp. 58-68
-
-
Husemann, Y.1
-
55
-
-
51849128358
-
Class I PI3K in oncogenic cellular transformation
-
Zhao, L. & Vogt, P. K. Class I PI3K in oncogenic cellular transformation. Oncogene 27, 5486-5496 (2008).
-
(2008)
Oncogene
, vol.27
, pp. 5486-5496
-
-
Zhao, L.1
Vogt, P.K.2
-
56
-
-
38949218379
-
Genomic imbalances in 5918 malignant epithelial tumors: An explorative meta-analysis of chromosomal CGH data
-
Baudis, M. Genomic imbalances in 5918 malignant epithelial tumors: an explorative meta-analysis of chromosomal CGH data. BMC Cancer 7, 226 (2007).
-
(2007)
BMC Cancer
, vol.7
, pp. 226
-
-
Baudis, M.1
-
57
-
-
0000629930
-
Selection of successive tumour lines for metastasis
-
Fidler, I. J. Selection of successive tumour lines for metastasis. Nat. New Biol. 242, 148-149 (1973).
-
(1973)
Nat. New Biol
, vol.242
, pp. 148-149
-
-
Fidler, I.J.1
-
58
-
-
0015536339
-
An autopsy study of metastatic sites of breast cancer
-
Viadana, E., Cotter, R., Pickren, J. W. & Bross, I. D. An autopsy study of metastatic sites of breast cancer. Cancer Res. 33, 179-181 (1973).
-
(1973)
Cancer Res
, vol.33
, pp. 179-181
-
-
Viadana, E.1
Cotter, R.2
Pickren, J.W.3
Bross, I.D.4
-
59
-
-
0022969737
-
Haematogenous metastatic patterns in colonic carcinoma: An analysis of 1541 necropsies
-
Weiss, L. et al. Haematogenous metastatic patterns in colonic carcinoma: an analysis of 1541 necropsies. J. Pathol. 150, 195-203 (1986).
-
(1986)
J. Pathol
, vol.150
, pp. 195-203
-
-
Weiss, L.1
-
60
-
-
0024212286
-
Metastatic patterns of renal carcinoma: An analysis of 687 necropsies
-
Weiss, L. et al. Metastatic patterns of renal carcinoma: an analysis of 687 necropsies. J. Cancer Res. Clin. Oncol. 114, 605-612 (1988).
-
(1988)
J. Cancer Res. Clin. Oncol
, vol.114
, pp. 605-612
-
-
Weiss, L.1
-
61
-
-
33748924308
-
Systemic cancer progression and tumor dormancy: Mathematical models meet single cell genomics
-
Klein, C. A. & Holzel, D. Systemic cancer progression and tumor dormancy: mathematical models meet single cell genomics. Cell Cycle 5, 1788-1798 (2006).
-
(2006)
Cell Cycle
, vol.5
, pp. 1788-1798
-
-
Klein, C.A.1
Holzel, D.2
-
62
-
-
0001777467
-
The results of radical operations for the cure of carcinoma of the breast
-
Halsted, W. S. I. The results of radical operations for the cure of carcinoma of the breast. Ann. Surg. 46, 1-19 (1907).
-
(1907)
Ann. Surg
, vol.46
, pp. 1-19
-
-
Halsted, W.S.I.1
-
63
-
-
0037158614
-
Twenty-five-year follow-up of a randomized trial comparing radical mastectomy, total mastectomy, and total mastectomy followed by irradiation
-
Fisher, B. et al. Twenty-five-year follow-up of a randomized trial comparing radical mastectomy, total mastectomy, and total mastectomy followed by irradiation. N. Engl. J. Med. 347, 567-575 (2002).
-
(2002)
N. Engl. J. Med
, vol.347
, pp. 567-575
-
-
Fisher, B.1
-
64
-
-
33644847224
-
Randomized trial comparing axillary clearance versus no axillary clearance in older patients with breast cancer: First results of International Breast Cancer Study Group Trial 10-93
-
Rudenstam, C. M. et al. Randomized trial comparing axillary clearance versus no axillary clearance in older patients with breast cancer: first results of International Breast Cancer Study Group Trial 10-93 J. Clin. Oncol. 24, 337-344 (2006).
-
(2006)
J. Clin. Oncol
, vol.24
, pp. 337-344
-
-
Rudenstam, C.M.1
-
65
-
-
0033198105
-
The dissection of internal mammary nodes does not improve the survival of breast cancer patients. 30-year results of a randomised trial
-
Veronesi, U., Marubini, E., Mariani, L., Valagussa, P. & Zucali, R. The dissection of internal mammary nodes does not improve the survival of breast cancer patients. 30-year results of a randomised trial. Eur. J. Cancer 35, 1320-1325 (1999).
-
(1999)
Eur. J. Cancer
, vol.35
, pp. 1320-1325
-
-
Veronesi, U.1
Marubini, E.2
Mariani, L.3
Valagussa, P.4
Zucali, R.5
-
66
-
-
58149191223
-
Efficacy of systematic pelvic lymphadenectomy in endometrial cancer (MRC ASTEC trial): A randomised study
-
Kitchener, H., Swart, A. M., Qian, Q., Amos, C. & Parmar, M. K. Efficacy of systematic pelvic lymphadenectomy in endometrial cancer (MRC ASTEC trial): a randomised study. Lancet 373, 125-136 (2009).
-
(2009)
Lancet
, vol.373
, pp. 125-136
-
-
Kitchener, H.1
Swart, A.M.2
Qian, Q.3
Amos, C.4
Parmar, M.K.5
-
67
-
-
33845599378
-
Ratio of trastuzumab levels in serum and cerebrospinal fluid is altered in HER2-positive breast cancer patients with brain metastases and impairment of blood-brain barrier
-
Stemmler, H. J. et al. Ratio of trastuzumab levels in serum and cerebrospinal fluid is altered in HER2-positive breast cancer patients with brain metastases and impairment of blood-brain barrier. Anticancer Drugs 18, 23-28 (2007).
-
(2007)
Anticancer Drugs
, vol.18
, pp. 23-28
-
-
Stemmler, H.J.1
-
68
-
-
0035869407
-
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
-
Slamon, D. J. et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N. Engl. J. Med. 344, 783-792 (2001).
-
(2001)
N. Engl. J. Med
, vol.344
, pp. 783-792
-
-
Slamon, D.J.1
-
69
-
-
33344478381
-
Adjuvant docetaxel or vinorelbine with or without trastuzumab for breast cancer
-
Joensuu, H. et al. Adjuvant docetaxel or vinorelbine with or without trastuzumab for breast cancer. N. Engl. J. Med. 354, 809-820 (2006).
-
(2006)
N. Engl. J. Med
, vol.354
, pp. 809-820
-
-
Joensuu, H.1
-
70
-
-
34250174543
-
Brain metastases: The HER2 paradigm
-
Lin, N. U. & Winer, E. P. Brain metastases: the HER2 paradigm. Clin. Cancer Res. 13, 1648-1655 (2007).
-
(2007)
Clin. Cancer Res
, vol.13
, pp. 1648-1655
-
-
Lin, N.U.1
Winer, E.P.2
-
71
-
-
0842333148
-
Immunomagnetic enrichment, genomic characterization, and prognostic impact of circulating melanoma cells
-
Ulmer, A. et al. Immunomagnetic enrichment, genomic characterization, and prognostic impact of circulating melanoma cells. Clin. Cancer Res. 10, 531-537 (2004).
-
(2004)
Clin. Cancer Res
, vol.10
, pp. 531-537
-
-
Ulmer, A.1
-
72
-
-
4143094988
-
Circulating tumor cells, disease progression, and survival in metastatic breast cancer
-
Cristofanilli, M. et al. Circulating tumor cells, disease progression, and survival in metastatic breast cancer. N. Engl. J. Med. 351, 781-791 (2004).
-
(2004)
N. Engl. J. Med
, vol.351
, pp. 781-791
-
-
Cristofanilli, M.1
-
73
-
-
55549115023
-
Circulating tumor cells in metastatic breast cancer: From prognostic stratification to modification of the staging system?
-
Dawood, S. et al. Circulating tumor cells in metastatic breast cancer: from prognostic stratification to modification of the staging system? Cancer 113, 2422-2430 (2008).
-
(2008)
Cancer
, vol.113
, pp. 2422-2430
-
-
Dawood, S.1
-
74
-
-
47949114668
-
Detection of mutations in EGFR in circulating lung-cancer cells
-
Maheswaran, S. et al. Detection of mutations in EGFR in circulating lung-cancer cells. N. Engl. J. Med. 359, 366-377 (2008).
-
(2008)
N. Engl. J. Med
, vol.359
, pp. 366-377
-
-
Maheswaran, S.1
-
75
-
-
37549071388
-
Adaptation versus selection: The origins of metastatic behavior
-
discussion 11479-80
-
Scheel, C., Onder, T., Karnoub, A. & Weinberg, R. A. Adaptation versus selection: the origins of metastatic behavior. Cancer Res. 67, 11476-11479; discussion 11479-80 (2007).
-
(2007)
Cancer Res
, vol.67
, pp. 11476-11479
-
-
Scheel, C.1
Onder, T.2
Karnoub, A.3
Weinberg, R.A.4
-
76
-
-
0038488950
-
A multigenic program mediating breast cancer metastasis to bone
-
Kang, Y. et al. A multigenic program mediating breast cancer metastasis to bone. Cancer Cell 3, 537-549 (2003).
-
(2003)
Cancer Cell
, vol.3
, pp. 537-549
-
-
Kang, Y.1
-
77
-
-
25444495269
-
Migrating cancer stem cells - an integrated concept of malignant tumour progression
-
Brabletz, T., Jung, A., Spaderna, S., Hlubek, F. & Kirchner, T. Migrating cancer stem cells - an integrated concept of malignant tumour progression. Nature Rev. Cancer 5, 744-749 (2005).
-
(2005)
Nature Rev. Cancer
, vol.5
, pp. 744-749
-
-
Brabletz, T.1
Jung, A.2
Spaderna, S.3
Hlubek, F.4
Kirchner, T.5
-
78
-
-
52549087785
-
-
Visvader, J. E. & Lindeman, G. J. Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nature Rev. Cancer 8, 755-768 (2008).
-
Visvader, J. E. & Lindeman, G. J. Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nature Rev. Cancer 8, 755-768 (2008).
-
-
-
-
79
-
-
57349143739
-
Efficient tumour formation by single human melanoma cells
-
Quintana, E. et al. Efficient tumour formation by single human melanoma cells. Nature 456, 593-598 (2008).
-
(2008)
Nature
, vol.456
, pp. 593-598
-
-
Quintana, E.1
-
80
-
-
33847347259
-
High resolution array-CGH analysis of single cells
-
Fiegler, H. et al. High resolution array-CGH analysis of single cells. Nucleic Acids Res. 35, e15 (2007).
-
(2007)
Nucleic Acids Res
, vol.35
-
-
Fiegler, H.1
-
81
-
-
42449119330
-
High-resolution array comparative genomic hybridization of single micrometastatic tumor cells
-
Fuhrmann, C. et al. High-resolution array comparative genomic hybridization of single micrometastatic tumor cells. Nucleic Acids Res. 36, e39 (2008).
-
(2008)
Nucleic Acids Res
, vol.36
-
-
Fuhrmann, C.1
-
82
-
-
56949091588
-
The direct molecular analysis of metastatic precursor cells in breast cancer: A chance for a better understanding of metastasis and for personalised medicine
-
Klein, C. A. The direct molecular analysis of metastatic precursor cells in breast cancer: A chance for a better understanding of metastasis and for personalised medicine. Eur. J. Cancer 44, 2721-2725 (2008).
-
(2008)
Eur. J. Cancer
, vol.44
, pp. 2721-2725
-
-
Klein, C.A.1
-
84
-
-
42649100970
-
Detection, clinical relevance and specific biological properties of disseminating tumour cells
-
Pantel, K., Brakenhoff, R. H. & Brandt, B. Detection, clinical relevance and specific biological properties of disseminating tumour cells. Nature Rev. Cancer 8, 329-340 (2008).
-
(2008)
Nature Rev. Cancer
, vol.8
, pp. 329-340
-
-
Pantel, K.1
Brakenhoff, R.H.2
Brandt, B.3
-
85
-
-
18244406590
-
Heterogeneous proliferative potential of occult metastatic cells in bone marrow of patients with solid epithelial tumors
-
Solakoglu, O. et al. Heterogeneous proliferative potential of occult metastatic cells in bone marrow of patients with solid epithelial tumors. Proc. Natl Acad. Sci. USA 99, 2246-2251 (2002).
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 2246-2251
-
-
Solakoglu, O.1
-
86
-
-
0017200032
-
Predicting the course of Gompertzian growth
-
Norton, L., Simon, R., Brereton, H. D. & Bogden, A. E. Predicting the course of Gompertzian growth. Nature 264, 542-545 (1976).
-
(1976)
Nature
, vol.264
, pp. 542-545
-
-
Norton, L.1
Simon, R.2
Brereton, H.D.3
Bogden, A.E.4
-
87
-
-
0025800109
-
Proliferation index in various stages of breast cancer determined by Ki-67 immunostaining
-
Pence, J. C., Kizilbash, A. M., Kerns, B. J., Marks, J. R. & Iglehart, J. D. Proliferation index in various stages of breast cancer determined by Ki-67 immunostaining. J. Surg. Oncol. 48, 11-20 (1991).
-
(1991)
J. Surg. Oncol
, vol.48
, pp. 11-20
-
-
Pence, J.C.1
Kizilbash, A.M.2
Kerns, B.J.3
Marks, J.R.4
Iglehart, J.D.5
-
88
-
-
0020499310
-
Carcinoma of the colon and rectum - growth rate
-
Bolin, S., Nilsson, E. & Sjodahl, R. Carcinoma of the colon and rectum - growth rate. Ann. Surg. 198, 151-158 (1983).
-
(1983)
Ann. Surg
, vol.198
, pp. 151-158
-
-
Bolin, S.1
Nilsson, E.2
Sjodahl, R.3
-
89
-
-
0027465152
-
Observations on the doubling time of prostate cancer. The use of serial prostate-specific antigen in patients with untreated disease as a measure of increasing cancer volume
-
Schmid, H. P., McNeal, J. E. & Stamey, T. A. Observations on the doubling time of prostate cancer. The use of serial prostate-specific antigen in patients with untreated disease as a measure of increasing cancer volume. Cancer 71, 2031-2040 (1993).
-
(1993)
Cancer
, vol.71
, pp. 2031-2040
-
-
Schmid, H.P.1
McNeal, J.E.2
Stamey, T.A.3
-
90
-
-
0032742243
-
Cell proliferation in prostate cancer patients with lymph node metastasis: A marker for progression
-
Cheng, L. et al. Cell proliferation in prostate cancer patients with lymph node metastasis: a marker for progression. Clin. Cancer Res. 5, 2820-2823 (1999).
-
(1999)
Clin. Cancer Res
, vol.5
, pp. 2820-2823
-
-
Cheng, L.1
-
91
-
-
0036721051
-
Metastatic prostate carcinoma to bone: Clinical and pathologic features associated with cancer-specific survival
-
Cheville, J. C. et al. Metastatic prostate carcinoma to bone: clinical and pathologic features associated with cancer-specific survival. Cancer 95, 1028-1036 (2002).
-
(2002)
Cancer
, vol.95
, pp. 1028-1036
-
-
Cheville, J.C.1
-
92
-
-
0023836307
-
Haematogenous dissemination of cells from human renal adenocarcinomas
-
Glaves, D., Huben, R. P. & Weiss, L. Haematogenous dissemination of cells from human renal adenocarcinomas. Br. J. Cancer 57, 32-35 (1988).
-
(1988)
Br. J. Cancer
, vol.57
, pp. 32-35
-
-
Glaves, D.1
Huben, R.P.2
Weiss, L.3
-
93
-
-
0021227896
-
Mechanisms of human tumor metastasis studied in patients with peritoneovenous shunts
-
Tarin, D. et al. Mechanisms of human tumor metastasis studied in patients with peritoneovenous shunts. Cancer Res. 44, 3584-3592 (1984).
-
(1984)
Cancer Res
, vol.44
, pp. 3584-3592
-
-
Tarin, D.1
-
94
-
-
0007712368
-
The dormant cancer cell
-
Hadfield, G. The dormant cancer cell. BMJ 4888, 607-610 (1954).
-
(1954)
BMJ
, vol.4888
, pp. 607-610
-
-
Hadfield, G.1
-
95
-
-
0027235985
-
Differential expression of proliferation- associated molecules in individual micrometastatic carcinoma cells
-
Pantel, K. et al. Differential expression of proliferation- associated molecules in individual micrometastatic carcinoma cells. J. Natl Cancer Inst. 85, 1419-1424 (1993).
-
(1993)
J. Natl Cancer Inst
, vol.85
, pp. 1419-1424
-
-
Pantel, K.1
-
96
-
-
23144461051
-
Genes that mediate breast cancer metastasis to lung
-
Minn, A. J. et al. Genes that mediate breast cancer metastasis to lung. Nature 436, 518-524 (2005).
-
(2005)
Nature
, vol.436
, pp. 518-524
-
-
Minn, A.J.1
-
97
-
-
34547566701
-
Transformation of different human breast epithelial cell types leads to distinct tumor phenotypes
-
Ince, T. A. et al. Transformation of different human breast epithelial cell types leads to distinct tumor phenotypes. Cancer Cell 12, 160-170 (2007).
-
(2007)
Cancer Cell
, vol.12
, pp. 160-170
-
-
Ince, T.A.1
|