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Volumn 3, Issue 7, 1997, Pages 730-737

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE GRANULOCYTIC LEUKEMIA; ADULT; AGED; ANIMAL EXPERIMENT; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; FEMALE; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; LEUKEMOGENESIS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TARGET CELL;

EID: 0030789242     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm0797-730     Document Type: Article
Times cited : (5846)

References (39)
  • 1
    • 0023202032 scopus 로고
    • Clonal development, stem-cell differentiation, and clinical remission in acute nonlymphocytic leukemia
    • Fialkow, P. et al. Clonal development, stem-cell differentiation, and clinical remission in acute nonlymphocytic leukemia. N. Engl. J. Med. 317, 468-473 (1987).
    • (1987) N. Engl. J. Med. , vol.317 , pp. 468-473
    • Fialkow, P.1
  • 2
    • 0020609330 scopus 로고
    • Stem cells in normal and leukemic hemopoiesis (Henry Stratton Lecture)
    • McCulloch, E. Stem cells in normal and leukemic hemopoiesis (Henry Stratton Lecture). Blood 62, 1-13 (1983).
    • (1983) Blood , vol.62 , pp. 1-13
    • McCulloch, E.1
  • 3
    • 0022913781 scopus 로고
    • Clonogenic cells in acute myeloblastic leukemia
    • Griffin, J. & Löwenberg, B. Clonogenic cells in acute myeloblastic leukemia. Blood 68, 1185-1195 (1986).
    • (1986) Blood , vol.68 , pp. 1185-1195
    • Griffin, J.1    Löwenberg, B.2
  • 4
    • 0028762431 scopus 로고
    • The molecular basis of leukemia
    • Cline, M.J. The molecular basis of leukemia. N. Engl. J. Med. 330, 328-336 (1994).
    • (1994) N. Engl. J. Med. , vol.330 , pp. 328-336
    • Cline, M.J.1
  • 5
    • 0023636659 scopus 로고
    • Cytogenetic studies on 519 consecutive de novo acute nonlymphocytic leukemias
    • Berger, R. et al. Cytogenetic studies on 519 consecutive de novo acute nonlymphocytic leukemias. Cancer Genet. Cytogenet. 29, 9-21 (1987).
    • (1987) Cancer Genet. Cytogenet. , vol.29 , pp. 9-21
    • Berger, R.1
  • 6
    • 0017162163 scopus 로고
    • Proposals for the classification of the acute leukemias
    • Bennett, J. et al. Proposals for the classification of the acute leukemias. Br. J. Haematol. 33, 451-458 (1976).
    • (1976) Br. J. Haematol. , vol.33 , pp. 451-458
    • Bennett, J.1
  • 7
    • 0019465758 scopus 로고
    • Acute nonlymphocytic leukemia: Heterogeneity of stem cell origin
    • Fialkow, P.J. et al. Acute nonlymphocytic leukemia: Heterogeneity of stem cell origin. Blood 57, 1068-1073 (1981).
    • (1981) Blood , vol.57 , pp. 1068-1073
    • Fialkow, P.J.1
  • 8
    • 0024520075 scopus 로고
    • Acute myeloid leukemia: Analysis of ras gene mutations and clonality defined by polymorphic X-linked loci
    • Bartram, C.R. et al. Acute myeloid leukemia: Analysis of ras gene mutations and clonality defined by polymorphic X-linked loci. Leukemia 3, 247-256 (1989).
    • (1989) Leukemia , vol.3 , pp. 247-256
    • Bartram, C.R.1
  • 9
    • 0027338129 scopus 로고
    • In situ hybridization on May-Grünwald Giemsa-stained bone marrow and blood smears of patients with hematologic disorders allows detection of cell-lineage-specific cytogenetic abnormalities
    • van Lom, K., Hagemeijer, A., Smit, E.M. & Lowenberg, B. In situ hybridization on May-Grünwald Giemsa-stained bone marrow and blood smears of patients with hematologic disorders allows detection of cell-lineage-specific cytogenetic abnormalities. Blood 82, 884-888 (1993).
    • (1993) Blood , vol.82 , pp. 884-888
    • Van Lom, K.1    Hagemeijer, A.2    Smit, E.M.3    Lowenberg, B.4
  • 10
    • 0022613519 scopus 로고
    • Differentiation of leukemia cells to polymorphonuclear leukocytes in patients with acute nonlymphoblastic leukemia
    • Fearon, E., Burke, P., Schiffer, C., Zehnbauer, B. & Vogelstein, B. Differentiation of leukemia cells to polymorphonuclear leukocytes in patients with acute nonlymphoblastic leukemia. N. Engl. J. Med. 315, 15-24 (1986).
    • (1986) N. Engl. J. Med. , vol.315 , pp. 15-24
    • Fearon, E.1    Burke, P.2    Schiffer, C.3    Zehnbauer, B.4    Vogelstein, B.5
  • 11
    • 0029142438 scopus 로고
    • Trisomy 4 in 'stem cell-like' leukemic cells of a patient with AML
    • Feuring-Buske, M. et al. Trisomy 4 in 'stem cell-like' leukemic cells of a patient with AML. Leukemia 9, 1318-1320 (1995).
    • (1995) Leukemia , vol.9 , pp. 1318-1320
    • Feuring-Buske, M.1
  • 12
    • 0027567880 scopus 로고
    • Stem cell origins of leukaemia and curability
    • Greaves, M.F. Stem cell origins of leukaemia and curability. Br. J. Cancer 67, 413-423 (1993).
    • (1993) Br. J. Cancer , vol.67 , pp. 413-423
    • Greaves, M.F.1
  • 13
    • 0023910577 scopus 로고
    • Clonal chromosomal abnormalities showing multiple-cell-lineage involvement in acute myeloid leukemia
    • Keinänen, M., Griffin, J., Bloomfield, C., Machnicki, J. & de la Chapelle, A. Clonal chromosomal abnormalities showing multiple-cell-lineage involvement in acute myeloid leukemia. N. Engl. J. Med. 318, 1153-1158 (1988).
    • (1988) N. Engl. J. Med. , vol.318 , pp. 1153-1158
    • Keinänen, M.1    Griffin, J.2    Bloomfield, C.3    Machnicki, J.4    De La Chapelle, A.5
  • 14
    • 0024240087 scopus 로고
    • Heterogeneity in acute myeloblastic leukemia
    • McCulloch, E.A. et al. Heterogeneity in acute myeloblastic leukemia. Leukemia 2, 38S-49S (1988).
    • (1988) Leukemia , vol.2
    • McCulloch, E.A.1
  • 15
    • 0028884211 scopus 로고
    • + subpopulations
    • + subpopulations. Blood 86, 2906-2912 (1995).
    • (1995) Blood , vol.86 , pp. 2906-2912
    • Haase, D.1
  • 16
    • 0029152177 scopus 로고
    • +lin) in acute myeloid leukemia
    • +lin) in acute myeloid leukemia. Blood 86, 1139-1147 (1995).
    • (1995) Blood , vol.86 , pp. 1139-1147
    • Mehrotra, B.1
  • 17
    • 16144365969 scopus 로고    scopus 로고
    • Identification of primitive hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow: Implications for gene therapy
    • Larochelle, A. et al. Identification of primitive hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow: Implications for gene therapy. Nature Med. 2, 1329-1337 (1996).
    • (1996) Nature Med. , vol.2 , pp. 1329-1337
    • Larochelle, A.1
  • 18
    • 0030221263 scopus 로고    scopus 로고
    • Normal and leukemic stem cells assayed in SCID mice
    • Dick, J.E. Normal and leukemic stem cells assayed in SCID mice. Semin. Immunol. 8, 197-206 (1996).
    • (1996) Semin. Immunol. , vol.8 , pp. 197-206
    • Dick, J.E.1
  • 19
    • 0030911358 scopus 로고    scopus 로고
    • Purification of primitive human hematopoietic cells capable of repopulating NOD/SCID mice
    • Bhatia, M., Wang, J., Kapp, U., Bonnet, D. & Dick, J. Purification of primitive human hematopoietic cells capable of repopulating NOD/SCID mice. Proc. Natl. Acad. Sci. USA 94, 5320-5325 (1997).
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 5320-5325
    • Bhatia, M.1    Wang, J.2    Kapp, U.3    Bonnet, D.4    Dick, J.5
  • 20
    • 0028091194 scopus 로고
    • A cell initiating human acute myeloid leukaemia after transplantation into SCID mice
    • Lapidot, T. et al. A cell initiating human acute myeloid leukaemia after transplantation into SCID mice. Nature 367, 645-648 (1994).
    • (1994) Nature , vol.367 , pp. 645-648
    • Lapidot, T.1
  • 21
    • 0028913342 scopus 로고
    • Engraftment of immune-deficient mice with primitive hematopoietic cells from beta-thalassemia and sickle cell anemia patients: Implications for evaluating human gene therapy protocols
    • Larochelle, A. et al. Engraftment of immune-deficient mice with primitive hematopoietic cells from beta-thalassemia and sickle cell anemia patients: Implications for evaluating human gene therapy protocols. Hum. Mol. Genet. 4, 163-172 (1995).
    • (1995) Hum. Mol. Genet. , vol.4 , pp. 163-172
    • Larochelle, A.1
  • 22
    • 0030916733 scopus 로고    scopus 로고
    • Primitive human hematopoietic cells are enriched in cord blood compared to adult bone marrow or mobilized peripheral blood as measured by the quantitative in vivo SCID-repopulating cell (SRC) assay
    • Wang, J., Doedens, M. & Dick, J. Primitive human hematopoietic cells are enriched in cord blood compared to adult bone marrow or mobilized peripheral blood as measured by the quantitative in vivo SCID-repopulating cell (SRC) assay. Blood 89, 3919-3924 (1997)
    • (1997) Blood , vol.89 , pp. 3919-3924
    • Wang, J.1    Doedens, M.2    Dick, J.3
  • 23
    • 0000839939 scopus 로고
    • The efficient design of transplantable tumor assays
    • Porter, E. & Berry, R. The efficient design of transplantable tumor assays. Br. J. Cancer 17, 583-595 (1964).
    • (1964) Br. J. Cancer , vol.17 , pp. 583-595
    • Porter, E.1    Berry, R.2
  • 24
    • 0019468220 scopus 로고
    • Limiting dilution assays for the determination of immunocompetent cell frequencies. I. Data analysis
    • Taswell, C. Limiting dilution assays for the determination of immunocompetent cell frequencies. I. Data analysis. J. Immunol. 126, 1614-1619 (1981).
    • (1981) J. Immunol. , vol.126 , pp. 1614-1619
    • Taswell, C.1
  • 25
    • 0021250078 scopus 로고
    • Antigenic analysis of hematopoiesis. III. A hematopoietic progenitor cell surface antigen defined by a monoclonal antibody raised against KG-1a cells
    • Civin, C. et al. Antigenic analysis of hematopoiesis. III. A hematopoietic progenitor cell surface antigen defined by a monoclonal antibody raised against KG-1a cells. J. Immunol. 133, 157-165 (1984).
    • (1984) J. Immunol. , vol.133 , pp. 157-165
    • Civin, C.1
  • 27
    • 0026782640 scopus 로고
    • Flow cytometry characterization of acute myeloid leukemia: IV. Comparison to the differentiation pathway of normal hematopoietic cells
    • Terstappen, L. et al. Flow cytometry characterization of acute myeloid leukemia: IV. Comparison to the differentiation pathway of normal hematopoietic cells. Leukemia 6, 993-1000 (1992).
    • (1992) Leukemia , vol.6 , pp. 993-1000
    • Terstappen, L.1
  • 28
    • 85088083527 scopus 로고    scopus 로고
    • Kinetic evidence of the regeneration of multilineage hematopoiesis from primitive cells in normal human bone marrow transplanted into immunodeficient mice
    • in the press
    • Cashman, J. et al. Kinetic evidence of the regeneration of multilineage hematopoiesis from primitive cells in normal human bone marrow transplanted into immunodeficient mice. Blood (in the press).
    • Blood
    • Cashman, J.1
  • 29
    • 0015594182 scopus 로고
    • In vitro colony formation by normal and leukemic human hematopoietic cells: Characterization of the colony-forming cells
    • Moore, M., Williams, N. & Metcalfe, D. In vitro colony formation by normal and leukemic human hematopoietic cells: Characterization of the colony-forming cells. J. Natl. Cancer Int. 50, 603 (1974).
    • (1974) J. Natl. Cancer Int. , vol.50 , pp. 603
    • Moore, M.1    Williams, N.2    Metcalfe, D.3
  • 30
    • 0030013530 scopus 로고    scopus 로고
    • Characterization of a hierarchy in human acute myeloid leukemia progenitor cells
    • Sutherland, H., Blair, A. & Zapf, R.W. Characterization of a hierarchy in human acute myeloid leukemia progenitor cells. Blood 87, 4754-4761 (1996).
    • (1996) Blood , vol.87 , pp. 4754-4761
    • Sutherland, H.1    Blair, A.2    Zapf, R.W.3
  • 31
    • 0027406463 scopus 로고
    • Expression of Thy-1 on human hematopoietic progenitor cells
    • Craig, W., Kay, R., Cutler, R.B. & Lansdorp, P.M. Expression of Thy-1 on human hematopoietic progenitor cells. J. Exp. Med. 177, 1331-1342 (1993).
    • (1993) J. Exp. Med. , vol.177 , pp. 1331-1342
    • Craig, W.1    Kay, R.2    Cutler, R.B.3    Lansdorp, P.M.4
  • 32
    • 0029912546 scopus 로고    scopus 로고
    • - subpopulation of acute myeloid leukemia
    • - subpopulation of acute myeloid leukemia. Blood 87, 2187-2194 (1996).
    • (1996) Blood , vol.87 , pp. 2187-2194
    • Terpstra, W.1
  • 33
    • 0026753367 scopus 로고
    • Propagation of human blastic myeloid leukemias in the SCID mouse
    • Sawyers, C., Gishizky, M., Quan, S., Golde, D. & Witte, O. Propagation of human blastic myeloid leukemias in the SCID mouse. Blood 79, 2089-2098 (1992).
    • (1992) Blood , vol.79 , pp. 2089-2098
    • Sawyers, C.1    Gishizky, M.2    Quan, S.3    Golde, D.4    Witte, O.5
  • 34
    • 0026582878 scopus 로고
    • The severe combined immunodeficient (SCID) mouse as a model for myeloid leukemias
    • Cesano, A. et al. The severe combined immunodeficient (SCID) mouse as a model for myeloid leukemias. Oncogene 7, 827-836 (1992).
    • (1992) Oncogene , vol.7 , pp. 827-836
    • Cesano, A.1
  • 35
    • 0028942312 scopus 로고
    • Highly purified primitive hematopoietic stem cells are PML-RARA negative and generate nonclonal progenitors in acute promyelocytic leukemia
    • Turhan, A.G. et al. Highly purified primitive hematopoietic stem cells are PML-RARA negative and generate nonclonal progenitors in acute promyelocytic leukemia. Blood 85, 2154-2161 (1995).
    • (1995) Blood , vol.85 , pp. 2154-2161
    • Turhan, A.G.1
  • 36
    • 0026581239 scopus 로고
    • Cytokine stimulation of multilineage hematopoiesis from immature human cells engrafted in SCID mice
    • Lapidot, T. et al. Cytokine stimulation of multilineage hematopoiesis from immature human cells engrafted in SCID mice. Science 255, 1137-1141 (1992).
    • (1992) Science , vol.255 , pp. 1137-1141
    • Lapidot, T.1
  • 37
    • 0028281703 scopus 로고
    • Immature human cord blood progenitors engraft and proliferate to high levels in immune-deficient SCID mice
    • Vormoor, J. et al. Immature human cord blood progenitors engraft and proliferate to high levels in immune-deficient SCID mice. Blood 83, 2489-2497 (1994).
    • (1994) Blood , vol.83 , pp. 2489-2497
    • Vormoor, J.1
  • 38
    • 13344262695 scopus 로고    scopus 로고
    • Normal and leukemic SCID-repopulating cells (SRC) co-exist in the bone marrow and peripheral blood from CML patients in chronic phase while leukemic SRC are detected in blast crisis
    • Sirard, C. et al. Normal and leukemic SCID-repopulating cells (SRC) co-exist in the bone marrow and peripheral blood from CML patients in chronic phase while leukemic SRC are detected in blast crisis. Blood 87, 1539-1548 (1996).
    • (1996) Blood , vol.87 , pp. 1539-1548
    • Sirard, C.1
  • 39
    • 0022780916 scopus 로고
    • Structure, organization and sequence of alpha satellite DNA from human chromosome 17: Evidence for evolution by unequal crossing-over and ancestral pentamer repeat shared with the human X chromosome
    • Waye, J.S. & Willard, H.F. Structure, organization and sequence of alpha satellite DNA from human chromosome 17: Evidence for evolution by unequal crossing-over and ancestral pentamer repeat shared with the human X chromosome. Mol. Cell. Biol. 6, 3156-3165 (1986).
    • (1986) Mol. Cell. Biol. , vol.6 , pp. 3156-3165
    • Waye, J.S.1    Willard, H.F.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.