From latent disseminated cells to overt metastasis: Genetic analysis of systemic breast cancer progression

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 13, 2003, Pages 7737-7742

  Schmidt Kittler, Oleg ^a   Ragg, Thomas ^b,g   Daskalakis, Angela ^c   Granzow, Martin ^b,g   Ahr, Andre ^d   Blankenstein, Thomas J F ^a   Kaufmann, Manfred ^d   Diebold, Joachim ^a   Arnholdt, Hans ^c   Müller, Peter ^c   Bischoff, Joachim ^e   Harich, Detlev ^e   Schlimok, Günter ^c   Riethmüller, Gert ^a   Eils, Roland ^b,f   Klein, Christoph A ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b Phase it Intelligent Solutions AG   (Germany)

^c KLINIKUM AUGSBURG   (Germany)

^d UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^e Klinik Bad Trissl   (Germany)

^f GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^g Quantiom Bioinformatics GmbH and Co KG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BONE MARROW; BREAST CANCER; CANCER CELL; CANCER GROWTH; CHROMOSOME ABERRATION; COMPARATIVE GENOMIC HYBRIDIZATION; DISSEMINATED CANCER; EPITHELIUM CELL; GENETIC ANALYSIS; GENOME; GENOTYPE; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; METASTASIS; PRIORITY JOURNAL; TUMOR CELL;

ALGORITHMS; BONE MARROW; BREAST NEOPLASMS; CADHERINS; CHROMOSOME ABERRATIONS; CHROMOSOMES, HUMAN, PAIR 16; COMPUTATIONAL BIOLOGY; DISEASE PROGRESSION; DOWN-REGULATION; GENOME; GENOTYPE; HUMANS; IN SITU HYBRIDIZATION; LOSS OF HETEROZYGOSITY; LYMPHATIC METASTASIS; MODELS, GENETIC; NEOPLASM METASTASIS; NUCLEIC ACID HYBRIDIZATION; PHYLOGENY; PROTEIN-TYROSINE KINASES; RETINOBLASTOMA PROTEIN; TIME FACTORS; UP-REGULATION;

EID: 0038271868     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.1331931100     Document Type: Article

References (39)

1. Fearon, E. R. & Vogelstein, B. (1990) Cell 61, 759-767.
2. van't Veer, L. J., Dai, H., van de Vijver, M. J., He, Y. D., Hart, A. A., Mao, M., Peterse, H. L., van der Kooy, K., Marton, M. J., Witteveen, A. T., et al. (2002) Nature 415, 530-536.
3. Bernards, R. & Weinberg, R. A. (2002) Nature 418, 823.
4. Hanahan, D. & Weinberg, R. A. (2000) Cell 100, 57-70.
5. Abbruzzese, J. L., Abbruzzese, M. C., Hess, K. R., Raber, M. N., Lenzi, R. & Frost, P. (1994) J. Clin. Oncol. 12, 1272-1280.
6. Riethmuller, G. & Klein, C. A. (2001) Semin. Cancer Biol. 11, 307-311.
7. Bernards, R. & Weinberg, R. A. (2002) Nature 419, 560 (lett.).
8. Edwards, P. A. (2002) Nature 419, 559-560 (lett.).
9. Sherley, J. L. (2002) Nature 419, 560 (lett.).
10. Braun, S., Pantel, K., Muller, P., Janni, W., Hepp, F., Kentenich, C. R., Gastroph, S., Wischnik, A., Dimpfl, T., Kindermann, G., et al. (2000) N. Engl. J. Med. 342, 525-533.
11. Pantel, K., Cote, R. J. & Fodstad, O. (1999) J. Natl. Cancer Inst. 91, 1113-1124.
12. Gebauer, G., Fehm, T., Merkle, E., Beck, E. P., Lang, N. & Jager, W. (2001) J. Clin. Oncol. 19, 3669-3674.
13. Oberneder, R., Riesenberg, R., Kriegmair, M., Bitzer, U., Klammert, R., Schneede, P., Hofstetter, A., Riethmuller, G. & Pantel, K. (1994) Urol. Res. 22, 3-8.
14. Pantel, K., Schlimok, G., Kutter, D., Schaller, G., Genz, T., Wiebecke, B., Backmann, R., Funke, I. & Riethmüller, G. (1991) Cancer Res. 51, 4712-4715.
15. Muller, P., Weckermann, D., Riethmuller, G. & Schlimok, G. (1996) Cancer Genet. Cytogenet. 88, 8-16.
16. Klein, C. A., Schmidt-Kittler, O., Schardt, J. A., Pantel, K., Speicher, M. R. & Riethmuller, G. (1999) Proc. Natl. Acad. Sci. USA 96, 4494-4499.
17. Klein, C. A., Blankenstein, T. J., Schmidt-Kittler, O., Petronio, M., Polzer, B., Stoecklein, N. H. & Riethmuller, G. (2002) Lancet 360, 683-689.
18. Stoecklein, N. H., Erbersdobler, A., Schmidt-Kittler, O., Diebold, J., Schardt, J. A., Izbicki, J. R. & Klein, C. A. (2002) Am. J. Pathol. 161, 43-51.
19. Chano, T., Kontani, K., Teramoto, K., Okabe, H. & Ikegawa, S. (2002) Nat. Genet. 31, 285-288.
20. Ragg, T., Menzel, W., Baum, W. & Wigbers, M. (2002) Neurocomputing 43, 127-144.
21. Ragg, T. (2002) in AI Commun. 15, 61-74.
22. Bishop, C. M. (1995) Neural Networks for Pattern Recognition (Oxford Univ. Press, Oxford).
23. Empson, M. B. (2001) Pathology 33, 93-95.
24. Press, W. H., Flannery, B. P., Teukolsky, S. A. & Vetterling, W. T. (1993) Numerical Recipes in C (Cambridge Univ. Press, Cambridge, U.K.).
25. Kallioniemi, A., Kallioniemi, O. P., Piper, J., Tanner, M., Stokke, T., Chen, L., Smith, H. S., Pinkel, D., Gray, J. W. & Waldman, F. M. (1994) Proc. Natl. Acad. Sci. USA 91, 2156-2160.
26. Eisen, M. B., Spellman, P. T., Brown, P. O. & Botstein, D. (1998) Proc. Natl. Acad. Sci. USA 95, 14863-14868.
27. Artandi, S. E., Chang, S., Lee, S.L., Alson, S., Gottlieb, G. J., Chin, L. & DePinho, R. A. (2000) Nature 406, 641-645.
28. Maser, R. S. & DePinho, R. A. (2002) Science 297, 565-569.
29. Pihan, G. A. & Doxsey, S. J. (1999) Semin. Cancer Biol. 9, 289-302.
30. Greenblatt, M. S., Bennett, W. P., Hollstein, M. & Harris, C. C. (1994) Cancer Res. 54, 4855-4878.
31. Klein, C. A., Seidl, S., Petat-Dutter, K., Offner, S., Geigl, J. B., Schmidt-Kittler, O., Wendler, N., Passlick, B., Huber, R. M., Schlimok, G., et al. (2002) Nat. Biotechnol. 20, 387-392.
32. Cheng, C. W., Wu, P. E., Yu, J. C., Huang, C. S., Yue, C. T., Wu, C. W. & Shen, C. Y. (2001) Oncogene 20, 3814-3823.
33. Aubele, M., Mattis, A., Zitzelsberger, H., Walch, A., Kremer, M., Welzl, G., Hofler, H. & Werner, M. (2000) Int. J. Cancer 85, 82-86.
34. Buerger, H., Otterbach, F., Simon, R., Poremba, C., Diallo, R., Decker, T., Riethdorf, L., Brinkschmidt, C., Dockhorn-Dworniczak, B. & Boecker, W. (1999) J. Pathol. 187, 396-402.
35. Nishizaki, T., DeVries, S., Chew, K., Goodson, W. H., III, Ljung, B. M., Thor, A. & Waldman, F. M. (1997) Genes Chromosomes Cancer 19, 267-272.
36. Pandis, N., Teixeira, M. R., Adeyinka, A., Rizou, H., Bardi, G., Mertens, F., Andersen, J. A., Bondeson, L., Sfikas, K., Qvist, H., et al. (1998) Genes Chromosomes Cancer 22, 122-129.
37. Kuukasjarvi, T., Karhu, R., Tanner, M., Kahkonen, M., Schaffer, A., Nupponen, N., Pennanen, S., Kallioniemi, A., Kallioniemi, O. P. & Isola, J. (1997) Cancer Res. 57, 1597-1604.
38. Hoglund, M., Gisselsson, D., Sall, T. & Mitelman, F. (2002) Cancer Genet. Cytogenet. 135, 103-109.
39. Loeb, L. A., Loeb, K. R. & Anderson, J. P. (2003) Proc. Natl. Acad. Sci. USA 100, 776-781.