-
1
-
-
0031056437
-
Malignant bone pain: Pathophysiology and treatment
-
Mercadante S (1997) Malignant bone pain: pathophysiology and treatment. Pain 69: 1-18.
-
(1997)
Pain
, vol.69
, pp. 1-18
-
-
Mercadante, S.1
-
2
-
-
33846882630
-
Molecular pathogenesis of osteosarcoma
-
Kansara M, Thomas DM (2007) Molecular pathogenesis of osteosarcoma. DNA Cell Biol 26: 1-18.
-
(2007)
DNA Cell Biol
, vol.26
, pp. 1-18
-
-
Kansara, M.1
Thomas, D.M.2
-
3
-
-
33847356573
-
Markers of angiogenesis and clinical features in patients with sarcoma
-
DuBois S, Demetri G (2007) Markers of angiogenesis and clinical features in patients with sarcoma. Cancer 109: 813-819.
-
(2007)
Cancer
, vol.109
, pp. 813-819
-
-
DuBois, S.1
Demetri, G.2
-
4
-
-
33846109280
-
Anti-angiogenic therapy for osteosarcoma
-
Quan GM, Choong PF (2006) Anti-angiogenic therapy for osteosarcoma. Cancer Metastasis Rev 25: 707-713.
-
(2006)
Cancer Metastasis Rev
, vol.25
, pp. 707-713
-
-
Quan, G.M.1
Choong, P.F.2
-
5
-
-
85013312416
-
Tumor angiogenesis: Therapeutic implications
-
Folkman J (1971) Tumor angiogenesis: therapeutic implications. N Engl J Med 285: 1182-1186.
-
(1971)
N Engl J Med
, vol.285
, pp. 1182-1186
-
-
Folkman, J.1
-
6
-
-
1642453748
-
Phase II study of SU5416, a small molecule vascular endothelial growth factor tyrosine kinase receptor inhibitor, in patients with refractory multiple myeloma
-
Zangari M, Anaissie E, Stopeck A, Morimoto A, Tan N, et al. (2004) Phase II study of SU5416, a small molecule vascular endothelial growth factor tyrosine kinase receptor inhibitor, in patients with refractory multiple myeloma. Clin Cancer Res 10: 88-95.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 88-95
-
-
Zangari, M.1
Anaissie, E.2
Stopeck, A.3
Morimoto, A.4
Tan, N.5
-
7
-
-
17144454839
-
Efficacy of the angiogenesis inhibitor O-(chloroacetyl-carbamoyl)fumagillol (AGM-1470) on osteosarcoma growth and lung metastasis in rats
-
Morishita T, Mii Y, Miyauchi Y, Miura S, Honoki K, et al. (1995) Efficacy of the angiogenesis inhibitor O-(chloroacetyl-carbamoyl)fumagillol (AGM-1470) on osteosarcoma growth and lung metastasis in rats. Jpn J Clin Oncol 25: 25-31.
-
(1995)
Jpn J Clin Oncol
, vol.25
, pp. 25-31
-
-
Morishita, T.1
Mii, Y.2
Miyauchi, Y.3
Miura, S.4
Honoki, K.5
-
8
-
-
35848966147
-
Bone metastases in breast cancer: Higher prevalence of osteosclerotic lesions
-
Quattrocchi CC, Piciucchi S, Sammarra M, Santini D, Vincenzi B, et al. (2007) Bone metastases in breast cancer: higher prevalence of osteosclerotic lesions. Radiol Med 112: 1049-1059.
-
(2007)
Radiol Med
, vol.112
, pp. 1049-1059
-
-
Quattrocchi, C.C.1
Piciucchi, S.2
Sammarra, M.3
Santini, D.4
Vincenzi, B.5
-
9
-
-
0041629312
-
Clodronate for treatment of bone metastases in hormone refractory prostate cancer
-
Hering F, Rodrigues PR, Lipay M (2003) Clodronate for treatment of bone metastases in hormone refractory prostate cancer. Int Braz J Urol 29: 228-233.
-
(2003)
Int Braz J Urol
, vol.29
, pp. 228-233
-
-
Hering, F.1
Rodrigues, P.R.2
Lipay, M.3
-
11
-
-
0036875489
-
Targeting tumor vasculature: Reality or a dream?
-
Satchi-Fainaro R (2002) Targeting tumor vasculature: reality or a dream? J Drug Target 10: 529-533.
-
(2002)
J Drug Target
, vol.10
, pp. 529-533
-
-
Satchi-Fainaro, R.1
-
12
-
-
33746961096
-
Water-soluble HPMA copolymer-prostaglandin E1 conjugates containing a cathepsin K sensitive spacer
-
Pan H, Kopeckova P, Wang D, Yang J, Miller S, et al. (2006) Water-soluble HPMA copolymer-prostaglandin E1 conjugates containing a cathepsin K sensitive spacer. J Drug Target 14: 425-435.
-
(2006)
J Drug Target
, vol.14
, pp. 425-435
-
-
Pan, H.1
Kopeckova, P.2
Wang, D.3
Yang, J.4
Miller, S.5
-
13
-
-
2342586114
-
Targeting angiogenesis with a conjugate of HPMA copolymer and TNP-470
-
Satchi-Fainaro R, Puder M, Davies JW, Tran HT, Sampson DA, et al. (2004) Targeting angiogenesis with a conjugate of HPMA copolymer and TNP-470. Nat Med 10: 255-261.
-
(2004)
Nat Med
, vol.10
, pp. 255-261
-
-
Satchi-Fainaro, R.1
Puder, M.2
Davies, J.W.3
Tran, H.T.4
Sampson, D.A.5
-
14
-
-
20244381828
-
Inhibition of vessel permeability by TNP-470 and its polymer conjugate, caplostatin
-
Satchi-Fainaro R, Mamluk R, Wang L, Short SM, Nagy JA, et al. (2005) Inhibition of vessel permeability by TNP-470 and its polymer conjugate, caplostatin. Cancer Cell 7: 251-261.
-
(2005)
Cancer Cell
, vol.7
, pp. 251-261
-
-
Satchi-Fainaro, R.1
Mamluk, R.2
Wang, L.3
Short, S.M.4
Nagy, J.A.5
-
15
-
-
33745703563
-
Polymer therapeutics: Concepts and applications
-
Haag R, Kratz F (2006) Polymer therapeutics: concepts and applications. Angew Chem Int Ed Engl 45: 1198-1215.
-
(2006)
Angew Chem Int Ed Engl
, vol.45
, pp. 1198-1215
-
-
Haag, R.1
Kratz, F.2
-
16
-
-
33744736980
-
A novel noninvasive model of endometriosis for monitoring the efficacy of antiangiogenic therapy
-
Becker CM, Wright RD, Satchi-Fainaro R, Funakoshi T, Folkman J, et al. (2006) A novel noninvasive model of endometriosis for monitoring the efficacy of antiangiogenic therapy. Am J Pathol 168: 2074-2084.
-
(2006)
Am J Pathol
, vol.168
, pp. 2074-2084
-
-
Becker, C.M.1
Wright, R.D.2
Satchi-Fainaro, R.3
Funakoshi, T.4
Folkman, J.5
-
17
-
-
0025204095
-
Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth
-
Ingber D, Fujita T, Kishimoto S, Sudo K, Kanamaru T, et al. (1990) Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth. Nature 348: 555-557.
-
(1990)
Nature
, vol.348
, pp. 555-557
-
-
Ingber, D.1
Fujita, T.2
Kishimoto, S.3
Sudo, K.4
Kanamaru, T.5
-
18
-
-
6544276582
-
A Phase I and pharmacokinetic study of TNP-470 administered weekly to patients with advanced cancer
-
Bhargava P, Marshall JL, Rizvi N, Dahut W, Yoe J, et al. (1999) A Phase I and pharmacokinetic study of TNP-470 administered weekly to patients with advanced cancer. Clin Cancer Res 5: 1989-1995.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 1989-1995
-
-
Bhargava, P.1
Marshall, J.L.2
Rizvi, N.3
Dahut, W.4
Yoe, J.5
-
19
-
-
0022858683
-
A new concept for macromolecular therapeutics in cancer chemotherapy: Mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs
-
Matsumura Y, Maeda H (1986) A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs. Cancer Res 46: 6387-6392.
-
(1986)
Cancer Res
, vol.46
, pp. 6387-6392
-
-
Matsumura, Y.1
Maeda, H.2
-
20
-
-
33747758790
-
-
Satchi-Fainaro R, Duncan R, Barnes CM (2006) Polymer Therapeutics for Cancer: Current Status and Future Challenges. In: Satchi-Fainaro R, Duncan R, eds (2006) Polymer Therapeutics II: Polymers as Drugs, Conjugates and Gene Delivery Systems. Berlin, Heidelberg: Springer-Verlag. pp 1-68.
-
Satchi-Fainaro R, Duncan R, Barnes CM (2006) Polymer Therapeutics for Cancer: Current Status and Future Challenges. In: Satchi-Fainaro R, Duncan R, eds (2006) Polymer Therapeutics II: Polymers as Drugs, Conjugates and Gene Delivery Systems. Berlin, Heidelberg: Springer-Verlag. pp 1-68.
-
-
-
-
21
-
-
33746985456
-
Polymer therapeutics- polymers as drugs, drug and protein conjugates and gene delivery systems: Past, present and future opportunities
-
Duncan R, Ringsdorf H, Satchi-Fainaro R (2006) Polymer therapeutics- polymers as drugs, drug and protein conjugates and gene delivery systems: past, present and future opportunities. J Drug Target 14: 337-341.
-
(2006)
J Drug Target
, vol.14
, pp. 337-341
-
-
Duncan, R.1
Ringsdorf, H.2
Satchi-Fainaro, R.3
-
22
-
-
35148877172
-
Malignant progression and blockade of angiogenesis in a murine transgenic model of neuroblastoma
-
Chesler L, Goldenberg DD, Seales IT, Satchi-Fainaro R, Grimmer M, et al. (2007) Malignant progression and blockade of angiogenesis in a murine transgenic model of neuroblastoma. Cancer Res 67: 9435-9442.
-
(2007)
Cancer Res
, vol.67
, pp. 9435-9442
-
-
Chesler, L.1
Goldenberg, D.D.2
Seales, I.T.3
Satchi-Fainaro, R.4
Grimmer, M.5
-
23
-
-
46949110744
-
An orally delivered small-molecule formulation with antiangiogenic and anticancer activity
-
Benny O, Fainaru O, Adini A, Cassiola F, Bazinet L, et al. (2008) An orally delivered small-molecule formulation with antiangiogenic and anticancer activity. Nat Biotechnol 26: 799-807.
-
(2008)
Nat Biotechnol
, vol.26
, pp. 799-807
-
-
Benny, O.1
Fainaru, O.2
Adini, A.3
Cassiola, F.4
Bazinet, L.5
-
24
-
-
33748526850
-
A chemical and genetic approach to the mode of action of fumagillin
-
Zhang Y, Yeh JR, Mara A, Ju R, Hines JF, et al. (2006) A chemical and genetic approach to the mode of action of fumagillin. Chem Biol 13: 1001-1009.
-
(2006)
Chem Biol
, vol.13
, pp. 1001-1009
-
-
Zhang, Y.1
Yeh, J.R.2
Mara, A.3
Ju, R.4
Hines, J.F.5
-
25
-
-
44649174395
-
Hybrids of 1-deoxynojirimycin and aryl-1,2,3-triazoles and biological studies related to angiogenesis
-
Zhao Y, Zhou Y, O'Boyle KM, Murphy PV (2008) Hybrids of 1-deoxynojirimycin and aryl-1,2,3-triazoles and biological studies related to angiogenesis. Bioorg Med Chem 16: 6333-6337.
-
(2008)
Bioorg Med Chem
, vol.16
, pp. 6333-6337
-
-
Zhao, Y.1
Zhou, Y.2
O'Boyle, K.M.3
Murphy, P.V.4
-
26
-
-
41149173642
-
Ectopic expression of methionine aminopeptidase-2 causes cell transformation and stimulates proliferation
-
Tucker LA, Zhang Q, Sheppard GS, Lou P, Jiang F, et al. (2008) Ectopic expression of methionine aminopeptidase-2 causes cell transformation and stimulates proliferation. Oncogene 27: 3967-3976.
-
(2008)
Oncogene
, vol.27
, pp. 3967-3976
-
-
Tucker, L.A.1
Zhang, Q.2
Sheppard, G.S.3
Lou, P.4
Jiang, F.5
-
27
-
-
51049117949
-
Biodistribution and pharmacokinetic studies of bone-targeting N-(2-hydroxypropyl)methacrylamide copolymer-alendronate conjugates
-
Pan H, Sima M, Kopeckova P, Wu K, Gao S, et al. (2008) Biodistribution and pharmacokinetic studies of bone-targeting N-(2-hydroxypropyl)methacrylamide copolymer-alendronate conjugates. Mol Pharm 5: 548-558.
-
(2008)
Mol Pharm
, vol.5
, pp. 548-558
-
-
Pan, H.1
Sima, M.2
Kopeckova, P.3
Wu, K.4
Gao, S.5
-
28
-
-
34548079335
-
Highly potent inhibitors of methionine aminopeptidase-2 based on a 1,2,4-triazole pharmacophore
-
Marino JP Jr, Fisher PW, Hofmann GA, Kirkpatrick RB, Janson CA, et al. (2007) Highly potent inhibitors of methionine aminopeptidase-2 based on a 1,2,4-triazole pharmacophore. J Med Chem 50: 3777-3785.
-
(2007)
J Med Chem
, vol.50
, pp. 3777-3785
-
-
Marino Jr, J.P.1
Fisher, P.W.2
Hofmann, G.A.3
Kirkpatrick, R.B.4
Janson, C.A.5
-
30
-
-
0014969997
-
Inorganic pyrophosphate in plasma, urine, and synovial fluid of patients with pyrophosphate arthropathy (chondrocalcinosis or pseudogout)
-
Russell RG, Bisaz S, Fleisch H, Currey HL, Rubinstein HM, et al. (1970) Inorganic pyrophosphate in plasma, urine, and synovial fluid of patients with pyrophosphate arthropathy (chondrocalcinosis or pseudogout). Lancet 2: 899-902.
-
(1970)
Lancet
, vol.2
, pp. 899-902
-
-
Russell, R.G.1
Bisaz, S.2
Fleisch, H.3
Currey, H.L.4
Rubinstein, H.M.5
-
31
-
-
0035992775
-
Bisphosphonates as a foundation of drug delivery to bone
-
Uludag H (2002) Bisphosphonates as a foundation of drug delivery to bone. Curr Pharm Des 8: 1929-1944.
-
(2002)
Curr Pharm Des
, vol.8
, pp. 1929-1944
-
-
Uludag, H.1
-
32
-
-
0033065233
-
Bisphosphonates: From the laboratory to the clinic and back again
-
Russell RG, Rogers MJ (1999) Bisphosphonates: from the laboratory to the clinic and back again. Bone 25: 97-106.
-
(1999)
Bone
, vol.25
, pp. 97-106
-
-
Russell, R.G.1
Rogers, M.J.2
-
34
-
-
0037087719
-
Hepatic drug targeting: Phase I evaluation of polymer-bound doxorubicin
-
Seymour LW, Ferry DR, Anderson D, Hesslewood S, Julyan PJ, et al. (2002) Hepatic drug targeting: phase I evaluation of polymer-bound doxorubicin. J Clin Oncol 20: 1668-1676.
-
(2002)
J Clin Oncol
, vol.20
, pp. 1668-1676
-
-
Seymour, L.W.1
Ferry, D.R.2
Anderson, D.3
Hesslewood, S.4
Julyan, P.J.5
-
35
-
-
0032976794
-
Bisphosphonates in the treatment of malignant bone disease
-
Berenson JR, Lipton A (1999) Bisphosphonates in the treatment of malignant bone disease. Annu Rev Med 50: 237-248.
-
(1999)
Annu Rev Med
, vol.50
, pp. 237-248
-
-
Berenson, J.R.1
Lipton, A.2
-
36
-
-
0033948488
-
The role of bisphosphonates in metastatic breast cancer
-
Hillner BE (2000) The role of bisphosphonates in metastatic breast cancer. Semin Radiat Oncol 10: 250-253.
-
(2000)
Semin Radiat Oncol
, vol.10
, pp. 250-253
-
-
Hillner, B.E.1
-
37
-
-
44649087001
-
Emerging role of bisphosphonates in the clinic-antitumor activity and prevention of metastasis to bone
-
Lipton A (2008) Emerging role of bisphosphonates in the clinic-antitumor activity and prevention of metastasis to bone. Cancer Treat Rev 34 Suppl 1: S25-30.
-
(2008)
Cancer Treat Rev
, vol.34
, Issue.SUPPL. 1
-
-
Lipton, A.1
-
38
-
-
18744424072
-
The new bisphosphonate, Zometa (zoledronic acid), decreases skeletal complications in both osteolytic and osteoblastic lesions: A comparison to pamidronate
-
Lipton A, Small E, Saad F, Gleason D, Gordon D, et al. (2002) The new bisphosphonate, Zometa (zoledronic acid), decreases skeletal complications in both osteolytic and osteoblastic lesions: a comparison to pamidronate. Cancer Invest 20 Suppl 2: 45-54.
-
(2002)
Cancer Invest
, vol.20
, Issue.SUPPL. 2
, pp. 45-54
-
-
Lipton, A.1
Small, E.2
Saad, F.3
Gleason, D.4
Gordon, D.5
-
40
-
-
33747363746
-
A 99mTc-labeled gemcitabine bisphosphonate drug conjugate as a probe to assess the potential for targeted chemotherapy of metastatic bone cancer
-
El-Mabhouh AA, Angelov CA, Cavell R, Mercer JR (2006) A 99mTc-labeled gemcitabine bisphosphonate drug conjugate as a probe to assess the potential for targeted chemotherapy of metastatic bone cancer. Nucl Med Biol 33: 715-722.
-
(2006)
Nucl Med Biol
, vol.33
, pp. 715-722
-
-
El-Mabhouh, A.A.1
Angelov, C.A.2
Cavell, R.3
Mercer, J.R.4
-
41
-
-
18844375069
-
Targeting of therapeutic agents to bone to treat metastatic cancer
-
Bagi CM (2005) Targeting of therapeutic agents to bone to treat metastatic cancer. Adv Drug Deliv Rev 57: 995-1010.
-
(2005)
Adv Drug Deliv Rev
, vol.57
, pp. 995-1010
-
-
Bagi, C.M.1
-
42
-
-
4344679079
-
Bone cancer pain: The effects of the bisphosphonate alendronate on pain, skeletal remodeling, tumor growth and tumor necrosis
-
Sevcik MA, Luger NM, Mach DB, Sabino MA, Peters CM, et al. (2004) Bone cancer pain: the effects of the bisphosphonate alendronate on pain, skeletal remodeling, tumor growth and tumor necrosis. Pain 111: 169-180.
-
(2004)
Pain
, vol.111
, pp. 169-180
-
-
Sevcik, M.A.1
Luger, N.M.2
Mach, D.B.3
Sabino, M.A.4
Peters, C.M.5
-
43
-
-
42349098792
-
Alendronate decreases orthotopic PC-3 prostate tumor growth and metastasis to prostate-draining lymph nodes in nude mice
-
Tuomela JM, Valta MP, Vaananen K, Harkonen PL (2008) Alendronate decreases orthotopic PC-3 prostate tumor growth and metastasis to prostate-draining lymph nodes in nude mice. BMC Cancer 8: 81.
-
(2008)
BMC Cancer
, vol.8
, pp. 81
-
-
Tuomela, J.M.1
Valta, M.P.2
Vaananen, K.3
Harkonen, P.L.4
-
44
-
-
33947540949
-
Alendronate induces antimigratory effects and inhibition of neutral phosphatases in UMR106 osteosarcoma cells
-
Molinuevo MS, Bruzzone L, Cortizo AM (2007) Alendronate induces antimigratory effects and inhibition of neutral phosphatases in UMR106 osteosarcoma cells. Eur J Pharmacol 562: 28-33.
-
(2007)
Eur J Pharmacol
, vol.562
, pp. 28-33
-
-
Molinuevo, M.S.1
Bruzzone, L.2
Cortizo, A.M.3
-
45
-
-
12544258226
-
Alendronate inhibits intraperitoneal dissemination in in vivo ovarian cancer model
-
Hashimoto K, Morishige K, Sawada K, Tahara M, Kawagishi R, et al. (2005) Alendronate inhibits intraperitoneal dissemination in in vivo ovarian cancer model. Cancer Res 65: 540-545.
-
(2005)
Cancer Res
, vol.65
, pp. 540-545
-
-
Hashimoto, K.1
Morishige, K.2
Sawada, K.3
Tahara, M.4
Kawagishi, R.5
-
46
-
-
33846483160
-
Alendronate suppresses tumor angiogenesis by inhibiting Rho activation of endothelial cells
-
Hashimoto K, Morishige K, Sawada K, Tahara M, Shimizu S, et al. (2007) Alendronate suppresses tumor angiogenesis by inhibiting Rho activation of endothelial cells. Biochem Biophys Res Commun 354: 478-484.
-
(2007)
Biochem Biophys Res Commun
, vol.354
, pp. 478-484
-
-
Hashimoto, K.1
Morishige, K.2
Sawada, K.3
Tahara, M.4
Shimizu, S.5
-
47
-
-
33947109369
-
Bisphosphonates: Mode of action and pharmacology
-
Russell RG (2007) Bisphosphonates: mode of action and pharmacology. Pediatrics 119 Suppl 2: S150-162.
-
(2007)
Pediatrics
, vol.119
, Issue.SUPPL. 2
-
-
Russell, R.G.1
-
48
-
-
1942454714
-
Alendronate regulates cell invasion and MMP-2 secretion in human osteosarcoma cell lines
-
Cheng YY, Huang L, Lee KM, Li K, Kumta SM (2004) Alendronate regulates cell invasion and MMP-2 secretion in human osteosarcoma cell lines. Pediatr Blood Cancer 42: 410-415.
-
(2004)
Pediatr Blood Cancer
, vol.42
, pp. 410-415
-
-
Cheng, Y.Y.1
Huang, L.2
Lee, K.M.3
Li, K.4
Kumta, S.M.5
-
49
-
-
38349023103
-
Cathepsins and osteosarcoma: Expression analysis identifies cathepsin K as an indicator of metastasis
-
Husmann K, Muff R, Bolander ME, Sarkar G, Born W, et al. (2008) Cathepsins and osteosarcoma: Expression analysis identifies cathepsin K as an indicator of metastasis. Mol Carcinog 47: 66-73.
-
(2008)
Mol Carcinog
, vol.47
, pp. 66-73
-
-
Husmann, K.1
Muff, R.2
Bolander, M.E.3
Sarkar, G.4
Born, W.5
-
51
-
-
65349136231
-
-
PLoS ONE in press
-
Segal E, Pan H, Ofek P, Udagawa T, Kopeckova P, et al. (2009) A novel combined targeted anticancer and anti-angiogenic polymer therapeutic. PLoS ONE in press.
-
(2009)
A novel combined targeted anticancer and anti-angiogenic polymer therapeutic
-
-
Segal, E.1
Pan, H.2
Ofek, P.3
Udagawa, T.4
Kopeckova, P.5
-
52
-
-
46449134613
-
Phase I/ II study of biweekly paclitaxel and radiation in androgen-ablated locally advanced prostate cancer
-
Sanfilippo NJ, Taneja SS, Chachoua A, Lepor H, Formenti SC (2008) Phase I/ II study of biweekly paclitaxel and radiation in androgen-ablated locally advanced prostate cancer. J Clin Oncol 26: 2973-2978.
-
(2008)
J Clin Oncol
, vol.26
, pp. 2973-2978
-
-
Sanfilippo, N.J.1
Taneja, S.S.2
Chachoua, A.3
Lepor, H.4
Formenti, S.C.5
-
53
-
-
0037097705
-
Spectrophotometric determination of alendronate in pharmaceutical formulations via complex formation with Fe(III) ions
-
Kuljanin J, Jankovic I, Nedeljkovic J, Prstojevic D, Marinkovic V (2002) Spectrophotometric determination of alendronate in pharmaceutical formulations via complex formation with Fe(III) ions. J Pharm Biomed Anal 28: 1215-1220.
-
(2002)
J Pharm Biomed Anal
, vol.28
, pp. 1215-1220
-
-
Kuljanin, J.1
Jankovic, I.2
Nedeljkovic, J.3
Prstojevic, D.4
Marinkovic, V.5
-
54
-
-
0030031898
-
Expression of vascular permeability factor/vascular endothelial growth factor by melanoma cells increases tumor growth, angiogenesis, and experimental metastasis
-
Claffey KP, Brown LF, del Aguila LF, Tognazzi K, Yeo KT, et al. (1996) Expression of vascular permeability factor/vascular endothelial growth factor by melanoma cells increases tumor growth, angiogenesis, and experimental metastasis. Cancer Res 56: 172-181.
-
(1996)
Cancer Res
, vol.56
, pp. 172-181
-
-
Claffey, K.P.1
Brown, L.F.2
del Aguila, L.F.3
Tognazzi, K.4
Yeo, K.T.5
-
55
-
-
84940142489
-
Vascular reactions to histamine, histamine-liberator and leukotaxine in the skin of guinea-pigs
-
Miles AA, Miles EM (1952) Vascular reactions to histamine, histamine-liberator and leukotaxine in the skin of guinea-pigs. J Physiol 118: 228-257.
-
(1952)
J Physiol
, vol.118
, pp. 228-257
-
-
Miles, A.A.1
Miles, E.M.2
-
56
-
-
0026083903
-
Tumor angiogenesis and metastasis-correlation in invasive breast carcinoma
-
Weidner N, Semple JP, Welch WR, Folkman J (1991) Tumor angiogenesis and metastasis-correlation in invasive breast carcinoma. N Engl J Med 324: 1-8.
-
(1991)
N Engl J Med
, vol.324
, pp. 1-8
-
-
Weidner, N.1
Semple, J.P.2
Welch, W.R.3
Folkman, J.4
-
57
-
-
0035816143
-
Polymer-drug conjugates, PDEPT and PELT: Basic principles for design and transfer from the laboratory to clinic
-
Duncan R, Gac-Breton S, Keane R, Musila R, Sat YN, et al. (2001) Polymer-drug conjugates, PDEPT and PELT: basic principles for design and transfer from the laboratory to clinic. J Control Release 74: 135-146.
-
(2001)
J Control Release
, vol.74
, pp. 135-146
-
-
Duncan, R.1
Gac-Breton, S.2
Keane, R.3
Musila, R.4
Sat, Y.N.5
-
58
-
-
0036842215
-
Vascular permeability factor/vascular endothelial growth factor: A critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy
-
Dvorak HF (2002) Vascular permeability factor/vascular endothelial growth factor: a critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy. J Clin Oncol 20: 4368-4380.
-
(2002)
J Clin Oncol
, vol.20
, pp. 4368-4380
-
-
Dvorak, H.F.1
-
59
-
-
33747117688
-
Hydroxybisphosphonate-containing polymeric drug-delivery systems designed for targeting into bone tissue
-
Hrubý M, Etrych T, Kučka J, Forsterová M, Ulbrich K (2006) Hydroxybisphosphonate-containing polymeric drug-delivery systems designed for targeting into bone tissue. Journal of Applied Polymer Science 101: 3192-3201.
-
(2006)
Journal of Applied Polymer Science
, vol.101
, pp. 3192-3201
-
-
Hrubý, M.1
Etrych, T.2
Kučka, J.3
Forsterová, M.4
Ulbrich, K.5
-
60
-
-
0141606725
-
Synthesis and evaluation of water-soluble polymeric bone-targeted drug delivery systems
-
Wang D, Miller S, Sima M, Kopečková P, Kopeček J (2003) Synthesis and evaluation of water-soluble polymeric bone-targeted drug delivery systems. Bioconjug Chem 14: 853-859.
-
(2003)
Bioconjug Chem
, vol.14
, pp. 853-859
-
-
Wang, D.1
Miller, S.2
Sima, M.3
Kopečková, P.4
Kopeček, J.5
-
61
-
-
4644259034
-
Current strategy of chemotherapy for reflactory bone and soft tissue sarcomas]
-
Chuman H (2004) [Current strategy of chemotherapy for reflactory bone and soft tissue sarcomas]. Gan To Kagaku Ryoho 31: 1331-1339.
-
(2004)
Gan To Kagaku Ryoho
, vol.31
, pp. 1331-1339
-
-
Chuman, H.1
-
62
-
-
34249723214
-
Opportunities for improving the therapeutic ratio for patients with sarcoma
-
Wunder JS, Nielsen TO, Maki RG, O'Sullivan B, Alman BA (2007) Opportunities for improving the therapeutic ratio for patients with sarcoma. Lancet Oncol 8: 513-524.
-
(2007)
Lancet Oncol
, vol.8
, pp. 513-524
-
-
Wunder, J.S.1
Nielsen, T.O.2
Maki, R.G.3
O'Sullivan, B.4
Alman, B.A.5
-
63
-
-
0028248444
-
A polymeric drug delivery system for the simultaneous delivery of drugs activatable by enzymes and/or light
-
Krinick NL, Sun Y, Joyner D, Spikes JD, Straight RC, et al. (1994) A polymeric drug delivery system for the simultaneous delivery of drugs activatable by enzymes and/or light. J Biomat Sci Polym Ed 5: 303-324.
-
(1994)
J Biomat Sci Polym Ed
, vol.5
, pp. 303-324
-
-
Krinick, N.L.1
Sun, Y.2
Joyner, D.3
Spikes, J.D.4
Straight, R.C.5
-
64
-
-
9444268102
-
Combination chemotherapy and photodynamic therapy with N-(2-hydroxypropyl) methacrylamide copolymer-bound anticancer drugs inhibit human ovarian carcinoma heterotransplanted in nude mice
-
Peterson CM, Lu JM, Sun Y, Peterson CA, Shiah JG, et al. (1996) Combination chemotherapy and photodynamic therapy with N-(2-hydroxypropyl) methacrylamide copolymer-bound anticancer drugs inhibit human ovarian carcinoma heterotransplanted in nude mice. Cancer Res 56: 3980-3985.
-
(1996)
Cancer Res
, vol.56
, pp. 3980-3985
-
-
Peterson, C.M.1
Lu, J.M.2
Sun, Y.3
Peterson, C.A.4
Shiah, J.G.5
-
65
-
-
0034059468
-
Antitumor activity of N-(2-hydroxypropyl) methacrylamide copolymer-mesochlorin e6 and adriamycin conjugates in combination treatments
-
Shiah JG, Sun Y, Peterson CM, Straight RC, Kopeček J (2000) Antitumor activity of N-(2-hydroxypropyl) methacrylamide copolymer-mesochlorin e6 and adriamycin conjugates in combination treatments. Clin Cancer Res 6: 1008-1015.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 1008-1015
-
-
Shiah, J.G.1
Sun, Y.2
Peterson, C.M.3
Straight, R.C.4
Kopeček, J.5
-
66
-
-
21244493239
-
Polymer therapeutics designed for a combination therapy of hormone-dependent cancer
-
Vicent MJ, Greco F, Nicholson RI, Paul A, Griffiths PC, et al. (2005) Polymer therapeutics designed for a combination therapy of hormone-dependent cancer. Angew Chem Int Ed Engl 44: 4061-4066.
-
(2005)
Angew Chem Int Ed Engl
, vol.44
, pp. 4061-4066
-
-
Vicent, M.J.1
Greco, F.2
Nicholson, R.I.3
Paul, A.4
Griffiths, P.C.5
-
67
-
-
33846549188
-
Investigating the mechanism of enhanced cytotoxicity of HPMA copolymer-Dox-AGM in breast cancer cells
-
Greco F, Vicent MJ, Gee S, Jones AT, Gee J, et al. (2007) Investigating the mechanism of enhanced cytotoxicity of HPMA copolymer-Dox-AGM in breast cancer cells. J Control Release 117: 28-39.
-
(2007)
J Control Release
, vol.117
, pp. 28-39
-
-
Greco, F.1
Vicent, M.J.2
Gee, S.3
Jones, A.T.4
Gee, J.5
-
68
-
-
11844254414
-
Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy
-
Jain RK (2005) Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. Science 307: 58-62.
-
(2005)
Science
, vol.307
, pp. 58-62
-
-
Jain, R.K.1
-
69
-
-
65349154064
-
-
Mourad JJ, des Guetz G, Debbabi H, Levy BI (2007) Blood pressure rise following angiogenesis inhibition by bevacizumab. A crucial role for microcirculation. Ann Oncol.
-
Mourad JJ, des Guetz G, Debbabi H, Levy BI (2007) Blood pressure rise following angiogenesis inhibition by bevacizumab. A crucial role for microcirculation. Ann Oncol.
-
-
-
-
70
-
-
0037208589
-
Phase II, randomized trial comparing bevacizumab plus fluorouracil (FU)/leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer
-
Kabbinavar F, Hurwitz HI, Fehrenbacher L, Meropol NJ, Novotny WF, et al. (2003) Phase II, randomized trial comparing bevacizumab plus fluorouracil (FU)/leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer. J Clin Oncol 21: 60-65.
-
(2003)
J Clin Oncol
, vol.21
, pp. 60-65
-
-
Kabbinavar, F.1
Hurwitz, H.I.2
Fehrenbacher, L.3
Meropol, N.J.4
Novotny, W.F.5
-
71
-
-
18744377487
-
Bevacizumab in combination chemotherapy for colorectal and other cancers
-
Motl S (2005) Bevacizumab in combination chemotherapy for colorectal and other cancers. Am J Health Syst Pharm 62: 1021-1032.
-
(2005)
Am J Health Syst Pharm
, vol.62
, pp. 1021-1032
-
-
Motl, S.1
-
72
-
-
41549167668
-
A randomised phase III study on capecitabine
-
Tol J, Koopman M, Rodenburg CJ, Cats A, Creemers GJ, et al. (2008) A randomised phase III study on capecitabine, oxaliplatin and bevacizumab with or without cetuximab in first-line advanced colorectal cancer, the CAIRO2 study of the Dutch Colorectal Cancer Group (DCCG). An interim analysis of toxicity. Ann Oncol.
-
(2008)
oxaliplatin and bevacizumab with or without cetuximab in first-line advanced colorectal cancer, the CAIRO2 study of the Dutch Colorectal Cancer Group (DCCG). An interim analysis of toxicity. Ann Oncol
-
-
Tol, J.1
Koopman, M.2
Rodenburg, C.J.3
Cats, A.4
Creemers, G.J.5
-
73
-
-
27644568995
-
The inhibitory effect of alendronate, a nitrogen-containing bisphosphonate on the PI3K-Akt-NFkappaB pathway in osteosarcoma cells
-
Inoue R, Matsuki NA, Jing G, Kanematsu T, Abe K, et al. (2005) The inhibitory effect of alendronate, a nitrogen-containing bisphosphonate on the PI3K-Akt-NFkappaB pathway in osteosarcoma cells. Br J Pharmacol 146: 633-641.
-
(2005)
Br J Pharmacol
, vol.146
, pp. 633-641
-
-
Inoue, R.1
Matsuki, N.A.2
Jing, G.3
Kanematsu, T.4
Abe, K.5
-
74
-
-
0017708682
-
Metastatic osteosarcoma to lung: A clinicopathologic study of surgical biopsies and resections
-
Dunn D, Dehner LP (1977) Metastatic osteosarcoma to lung: a clinicopathologic study of surgical biopsies and resections. Cancer 40: 3054-3064.
-
(1977)
Cancer
, vol.40
, pp. 3054-3064
-
-
Dunn, D.1
Dehner, L.P.2
-
75
-
-
45549104510
-
-
Gomez Font R, Martinez Garcia ML, Olmos Martinez JM (2008) Osteochemonecrosis of the jaws due to bisphosphonate treatments. Update. Med Oral Patol Oral Cir Bucal 13: E318-324.
-
Gomez Font R, Martinez Garcia ML, Olmos Martinez JM (2008) Osteochemonecrosis of the jaws due to bisphosphonate treatments. Update. Med Oral Patol Oral Cir Bucal 13: E318-324.
-
-
-
|