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Volumn 4, Issue 4, 2009, Pages

Targeting angiogenesis-dependent calcified neoplasms using combined polymer therapeutics

Author keywords

[No Author keywords available]

Indexed keywords

ALENDRONIC ACID; ANTINEOPLASTIC AGENT; FUMAGILLOL CHLOROACETYLCARBAMATE; GLYCINE; N (2 HYDROXYPROPYL)METHACRYLAMIDE COPOLYMER; N (2 HYDROXYPROPYL)METHACRYLAMIDE COPOLYMER ALENDRONIC ACID FUMAGILLOL CHLOROACETYLCARBAMATE CONJUGATE; NORLEUCINE; PROLINE; UNCLASSIFIED DRUG; VASCULOTROPIN; POLYMER;

EID: 65349125338     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0005233     Document Type: Article
Times cited : (106)

References (75)
  • 1
    • 0031056437 scopus 로고    scopus 로고
    • Malignant bone pain: Pathophysiology and treatment
    • Mercadante S (1997) Malignant bone pain: pathophysiology and treatment. Pain 69: 1-18.
    • (1997) Pain , vol.69 , pp. 1-18
    • Mercadante, S.1
  • 2
    • 33846882630 scopus 로고    scopus 로고
    • Molecular pathogenesis of osteosarcoma
    • Kansara M, Thomas DM (2007) Molecular pathogenesis of osteosarcoma. DNA Cell Biol 26: 1-18.
    • (2007) DNA Cell Biol , vol.26 , pp. 1-18
    • Kansara, M.1    Thomas, D.M.2
  • 3
    • 33847356573 scopus 로고    scopus 로고
    • Markers of angiogenesis and clinical features in patients with sarcoma
    • DuBois S, Demetri G (2007) Markers of angiogenesis and clinical features in patients with sarcoma. Cancer 109: 813-819.
    • (2007) Cancer , vol.109 , pp. 813-819
    • DuBois, S.1    Demetri, G.2
  • 4
    • 33846109280 scopus 로고    scopus 로고
    • Anti-angiogenic therapy for osteosarcoma
    • Quan GM, Choong PF (2006) Anti-angiogenic therapy for osteosarcoma. Cancer Metastasis Rev 25: 707-713.
    • (2006) Cancer Metastasis Rev , vol.25 , pp. 707-713
    • Quan, G.M.1    Choong, P.F.2
  • 5
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • Folkman J (1971) Tumor angiogenesis: therapeutic implications. N Engl J Med 285: 1182-1186.
    • (1971) N Engl J Med , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 6
    • 1642453748 scopus 로고    scopus 로고
    • Phase II study of SU5416, a small molecule vascular endothelial growth factor tyrosine kinase receptor inhibitor, in patients with refractory multiple myeloma
    • Zangari M, Anaissie E, Stopeck A, Morimoto A, Tan N, et al. (2004) Phase II study of SU5416, a small molecule vascular endothelial growth factor tyrosine kinase receptor inhibitor, in patients with refractory multiple myeloma. Clin Cancer Res 10: 88-95.
    • (2004) Clin Cancer Res , vol.10 , pp. 88-95
    • Zangari, M.1    Anaissie, E.2    Stopeck, A.3    Morimoto, A.4    Tan, N.5
  • 7
    • 17144454839 scopus 로고
    • Efficacy of the angiogenesis inhibitor O-(chloroacetyl-carbamoyl)fumagillol (AGM-1470) on osteosarcoma growth and lung metastasis in rats
    • Morishita T, Mii Y, Miyauchi Y, Miura S, Honoki K, et al. (1995) Efficacy of the angiogenesis inhibitor O-(chloroacetyl-carbamoyl)fumagillol (AGM-1470) on osteosarcoma growth and lung metastasis in rats. Jpn J Clin Oncol 25: 25-31.
    • (1995) Jpn J Clin Oncol , vol.25 , pp. 25-31
    • Morishita, T.1    Mii, Y.2    Miyauchi, Y.3    Miura, S.4    Honoki, K.5
  • 8
    • 35848966147 scopus 로고    scopus 로고
    • Bone metastases in breast cancer: Higher prevalence of osteosclerotic lesions
    • Quattrocchi CC, Piciucchi S, Sammarra M, Santini D, Vincenzi B, et al. (2007) Bone metastases in breast cancer: higher prevalence of osteosclerotic lesions. Radiol Med 112: 1049-1059.
    • (2007) Radiol Med , vol.112 , pp. 1049-1059
    • Quattrocchi, C.C.1    Piciucchi, S.2    Sammarra, M.3    Santini, D.4    Vincenzi, B.5
  • 9
    • 0041629312 scopus 로고    scopus 로고
    • Clodronate for treatment of bone metastases in hormone refractory prostate cancer
    • Hering F, Rodrigues PR, Lipay M (2003) Clodronate for treatment of bone metastases in hormone refractory prostate cancer. Int Braz J Urol 29: 228-233.
    • (2003) Int Braz J Urol , vol.29 , pp. 228-233
    • Hering, F.1    Rodrigues, P.R.2    Lipay, M.3
  • 11
    • 0036875489 scopus 로고    scopus 로고
    • Targeting tumor vasculature: Reality or a dream?
    • Satchi-Fainaro R (2002) Targeting tumor vasculature: reality or a dream? J Drug Target 10: 529-533.
    • (2002) J Drug Target , vol.10 , pp. 529-533
    • Satchi-Fainaro, R.1
  • 12
    • 33746961096 scopus 로고    scopus 로고
    • Water-soluble HPMA copolymer-prostaglandin E1 conjugates containing a cathepsin K sensitive spacer
    • Pan H, Kopeckova P, Wang D, Yang J, Miller S, et al. (2006) Water-soluble HPMA copolymer-prostaglandin E1 conjugates containing a cathepsin K sensitive spacer. J Drug Target 14: 425-435.
    • (2006) J Drug Target , vol.14 , pp. 425-435
    • Pan, H.1    Kopeckova, P.2    Wang, D.3    Yang, J.4    Miller, S.5
  • 13
    • 2342586114 scopus 로고    scopus 로고
    • Targeting angiogenesis with a conjugate of HPMA copolymer and TNP-470
    • Satchi-Fainaro R, Puder M, Davies JW, Tran HT, Sampson DA, et al. (2004) Targeting angiogenesis with a conjugate of HPMA copolymer and TNP-470. Nat Med 10: 255-261.
    • (2004) Nat Med , vol.10 , pp. 255-261
    • Satchi-Fainaro, R.1    Puder, M.2    Davies, J.W.3    Tran, H.T.4    Sampson, D.A.5
  • 14
    • 20244381828 scopus 로고    scopus 로고
    • Inhibition of vessel permeability by TNP-470 and its polymer conjugate, caplostatin
    • Satchi-Fainaro R, Mamluk R, Wang L, Short SM, Nagy JA, et al. (2005) Inhibition of vessel permeability by TNP-470 and its polymer conjugate, caplostatin. Cancer Cell 7: 251-261.
    • (2005) Cancer Cell , vol.7 , pp. 251-261
    • Satchi-Fainaro, R.1    Mamluk, R.2    Wang, L.3    Short, S.M.4    Nagy, J.A.5
  • 15
    • 33745703563 scopus 로고    scopus 로고
    • Polymer therapeutics: Concepts and applications
    • Haag R, Kratz F (2006) Polymer therapeutics: concepts and applications. Angew Chem Int Ed Engl 45: 1198-1215.
    • (2006) Angew Chem Int Ed Engl , vol.45 , pp. 1198-1215
    • Haag, R.1    Kratz, F.2
  • 16
    • 33744736980 scopus 로고    scopus 로고
    • A novel noninvasive model of endometriosis for monitoring the efficacy of antiangiogenic therapy
    • Becker CM, Wright RD, Satchi-Fainaro R, Funakoshi T, Folkman J, et al. (2006) A novel noninvasive model of endometriosis for monitoring the efficacy of antiangiogenic therapy. Am J Pathol 168: 2074-2084.
    • (2006) Am J Pathol , vol.168 , pp. 2074-2084
    • Becker, C.M.1    Wright, R.D.2    Satchi-Fainaro, R.3    Funakoshi, T.4    Folkman, J.5
  • 17
    • 0025204095 scopus 로고
    • Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth
    • Ingber D, Fujita T, Kishimoto S, Sudo K, Kanamaru T, et al. (1990) Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth. Nature 348: 555-557.
    • (1990) Nature , vol.348 , pp. 555-557
    • Ingber, D.1    Fujita, T.2    Kishimoto, S.3    Sudo, K.4    Kanamaru, T.5
  • 18
    • 6544276582 scopus 로고    scopus 로고
    • A Phase I and pharmacokinetic study of TNP-470 administered weekly to patients with advanced cancer
    • Bhargava P, Marshall JL, Rizvi N, Dahut W, Yoe J, et al. (1999) A Phase I and pharmacokinetic study of TNP-470 administered weekly to patients with advanced cancer. Clin Cancer Res 5: 1989-1995.
    • (1999) Clin Cancer Res , vol.5 , pp. 1989-1995
    • Bhargava, P.1    Marshall, J.L.2    Rizvi, N.3    Dahut, W.4    Yoe, J.5
  • 19
    • 0022858683 scopus 로고
    • A new concept for macromolecular therapeutics in cancer chemotherapy: Mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs
    • Matsumura Y, Maeda H (1986) A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs. Cancer Res 46: 6387-6392.
    • (1986) Cancer Res , vol.46 , pp. 6387-6392
    • Matsumura, Y.1    Maeda, H.2
  • 20
    • 33747758790 scopus 로고    scopus 로고
    • Satchi-Fainaro R, Duncan R, Barnes CM (2006) Polymer Therapeutics for Cancer: Current Status and Future Challenges. In: Satchi-Fainaro R, Duncan R, eds (2006) Polymer Therapeutics II: Polymers as Drugs, Conjugates and Gene Delivery Systems. Berlin, Heidelberg: Springer-Verlag. pp 1-68.
    • Satchi-Fainaro R, Duncan R, Barnes CM (2006) Polymer Therapeutics for Cancer: Current Status and Future Challenges. In: Satchi-Fainaro R, Duncan R, eds (2006) Polymer Therapeutics II: Polymers as Drugs, Conjugates and Gene Delivery Systems. Berlin, Heidelberg: Springer-Verlag. pp 1-68.
  • 21
    • 33746985456 scopus 로고    scopus 로고
    • Polymer therapeutics- polymers as drugs, drug and protein conjugates and gene delivery systems: Past, present and future opportunities
    • Duncan R, Ringsdorf H, Satchi-Fainaro R (2006) Polymer therapeutics- polymers as drugs, drug and protein conjugates and gene delivery systems: past, present and future opportunities. J Drug Target 14: 337-341.
    • (2006) J Drug Target , vol.14 , pp. 337-341
    • Duncan, R.1    Ringsdorf, H.2    Satchi-Fainaro, R.3
  • 22
    • 35148877172 scopus 로고    scopus 로고
    • Malignant progression and blockade of angiogenesis in a murine transgenic model of neuroblastoma
    • Chesler L, Goldenberg DD, Seales IT, Satchi-Fainaro R, Grimmer M, et al. (2007) Malignant progression and blockade of angiogenesis in a murine transgenic model of neuroblastoma. Cancer Res 67: 9435-9442.
    • (2007) Cancer Res , vol.67 , pp. 9435-9442
    • Chesler, L.1    Goldenberg, D.D.2    Seales, I.T.3    Satchi-Fainaro, R.4    Grimmer, M.5
  • 23
    • 46949110744 scopus 로고    scopus 로고
    • An orally delivered small-molecule formulation with antiangiogenic and anticancer activity
    • Benny O, Fainaru O, Adini A, Cassiola F, Bazinet L, et al. (2008) An orally delivered small-molecule formulation with antiangiogenic and anticancer activity. Nat Biotechnol 26: 799-807.
    • (2008) Nat Biotechnol , vol.26 , pp. 799-807
    • Benny, O.1    Fainaru, O.2    Adini, A.3    Cassiola, F.4    Bazinet, L.5
  • 24
    • 33748526850 scopus 로고    scopus 로고
    • A chemical and genetic approach to the mode of action of fumagillin
    • Zhang Y, Yeh JR, Mara A, Ju R, Hines JF, et al. (2006) A chemical and genetic approach to the mode of action of fumagillin. Chem Biol 13: 1001-1009.
    • (2006) Chem Biol , vol.13 , pp. 1001-1009
    • Zhang, Y.1    Yeh, J.R.2    Mara, A.3    Ju, R.4    Hines, J.F.5
  • 25
    • 44649174395 scopus 로고    scopus 로고
    • Hybrids of 1-deoxynojirimycin and aryl-1,2,3-triazoles and biological studies related to angiogenesis
    • Zhao Y, Zhou Y, O'Boyle KM, Murphy PV (2008) Hybrids of 1-deoxynojirimycin and aryl-1,2,3-triazoles and biological studies related to angiogenesis. Bioorg Med Chem 16: 6333-6337.
    • (2008) Bioorg Med Chem , vol.16 , pp. 6333-6337
    • Zhao, Y.1    Zhou, Y.2    O'Boyle, K.M.3    Murphy, P.V.4
  • 26
    • 41149173642 scopus 로고    scopus 로고
    • Ectopic expression of methionine aminopeptidase-2 causes cell transformation and stimulates proliferation
    • Tucker LA, Zhang Q, Sheppard GS, Lou P, Jiang F, et al. (2008) Ectopic expression of methionine aminopeptidase-2 causes cell transformation and stimulates proliferation. Oncogene 27: 3967-3976.
    • (2008) Oncogene , vol.27 , pp. 3967-3976
    • Tucker, L.A.1    Zhang, Q.2    Sheppard, G.S.3    Lou, P.4    Jiang, F.5
  • 27
    • 51049117949 scopus 로고    scopus 로고
    • Biodistribution and pharmacokinetic studies of bone-targeting N-(2-hydroxypropyl)methacrylamide copolymer-alendronate conjugates
    • Pan H, Sima M, Kopeckova P, Wu K, Gao S, et al. (2008) Biodistribution and pharmacokinetic studies of bone-targeting N-(2-hydroxypropyl)methacrylamide copolymer-alendronate conjugates. Mol Pharm 5: 548-558.
    • (2008) Mol Pharm , vol.5 , pp. 548-558
    • Pan, H.1    Sima, M.2    Kopeckova, P.3    Wu, K.4    Gao, S.5
  • 28
    • 34548079335 scopus 로고    scopus 로고
    • Highly potent inhibitors of methionine aminopeptidase-2 based on a 1,2,4-triazole pharmacophore
    • Marino JP Jr, Fisher PW, Hofmann GA, Kirkpatrick RB, Janson CA, et al. (2007) Highly potent inhibitors of methionine aminopeptidase-2 based on a 1,2,4-triazole pharmacophore. J Med Chem 50: 3777-3785.
    • (2007) J Med Chem , vol.50 , pp. 3777-3785
    • Marino Jr, J.P.1    Fisher, P.W.2    Hofmann, G.A.3    Kirkpatrick, R.B.4    Janson, C.A.5
  • 30
    • 0014969997 scopus 로고
    • Inorganic pyrophosphate in plasma, urine, and synovial fluid of patients with pyrophosphate arthropathy (chondrocalcinosis or pseudogout)
    • Russell RG, Bisaz S, Fleisch H, Currey HL, Rubinstein HM, et al. (1970) Inorganic pyrophosphate in plasma, urine, and synovial fluid of patients with pyrophosphate arthropathy (chondrocalcinosis or pseudogout). Lancet 2: 899-902.
    • (1970) Lancet , vol.2 , pp. 899-902
    • Russell, R.G.1    Bisaz, S.2    Fleisch, H.3    Currey, H.L.4    Rubinstein, H.M.5
  • 31
    • 0035992775 scopus 로고    scopus 로고
    • Bisphosphonates as a foundation of drug delivery to bone
    • Uludag H (2002) Bisphosphonates as a foundation of drug delivery to bone. Curr Pharm Des 8: 1929-1944.
    • (2002) Curr Pharm Des , vol.8 , pp. 1929-1944
    • Uludag, H.1
  • 32
    • 0033065233 scopus 로고    scopus 로고
    • Bisphosphonates: From the laboratory to the clinic and back again
    • Russell RG, Rogers MJ (1999) Bisphosphonates: from the laboratory to the clinic and back again. Bone 25: 97-106.
    • (1999) Bone , vol.25 , pp. 97-106
    • Russell, R.G.1    Rogers, M.J.2
  • 35
    • 0032976794 scopus 로고    scopus 로고
    • Bisphosphonates in the treatment of malignant bone disease
    • Berenson JR, Lipton A (1999) Bisphosphonates in the treatment of malignant bone disease. Annu Rev Med 50: 237-248.
    • (1999) Annu Rev Med , vol.50 , pp. 237-248
    • Berenson, J.R.1    Lipton, A.2
  • 36
    • 0033948488 scopus 로고    scopus 로고
    • The role of bisphosphonates in metastatic breast cancer
    • Hillner BE (2000) The role of bisphosphonates in metastatic breast cancer. Semin Radiat Oncol 10: 250-253.
    • (2000) Semin Radiat Oncol , vol.10 , pp. 250-253
    • Hillner, B.E.1
  • 37
    • 44649087001 scopus 로고    scopus 로고
    • Emerging role of bisphosphonates in the clinic-antitumor activity and prevention of metastasis to bone
    • Lipton A (2008) Emerging role of bisphosphonates in the clinic-antitumor activity and prevention of metastasis to bone. Cancer Treat Rev 34 Suppl 1: S25-30.
    • (2008) Cancer Treat Rev , vol.34 , Issue.SUPPL. 1
    • Lipton, A.1
  • 38
    • 18744424072 scopus 로고    scopus 로고
    • The new bisphosphonate, Zometa (zoledronic acid), decreases skeletal complications in both osteolytic and osteoblastic lesions: A comparison to pamidronate
    • Lipton A, Small E, Saad F, Gleason D, Gordon D, et al. (2002) The new bisphosphonate, Zometa (zoledronic acid), decreases skeletal complications in both osteolytic and osteoblastic lesions: a comparison to pamidronate. Cancer Invest 20 Suppl 2: 45-54.
    • (2002) Cancer Invest , vol.20 , Issue.SUPPL. 2 , pp. 45-54
    • Lipton, A.1    Small, E.2    Saad, F.3    Gleason, D.4    Gordon, D.5
  • 40
    • 33747363746 scopus 로고    scopus 로고
    • A 99mTc-labeled gemcitabine bisphosphonate drug conjugate as a probe to assess the potential for targeted chemotherapy of metastatic bone cancer
    • El-Mabhouh AA, Angelov CA, Cavell R, Mercer JR (2006) A 99mTc-labeled gemcitabine bisphosphonate drug conjugate as a probe to assess the potential for targeted chemotherapy of metastatic bone cancer. Nucl Med Biol 33: 715-722.
    • (2006) Nucl Med Biol , vol.33 , pp. 715-722
    • El-Mabhouh, A.A.1    Angelov, C.A.2    Cavell, R.3    Mercer, J.R.4
  • 41
    • 18844375069 scopus 로고    scopus 로고
    • Targeting of therapeutic agents to bone to treat metastatic cancer
    • Bagi CM (2005) Targeting of therapeutic agents to bone to treat metastatic cancer. Adv Drug Deliv Rev 57: 995-1010.
    • (2005) Adv Drug Deliv Rev , vol.57 , pp. 995-1010
    • Bagi, C.M.1
  • 42
    • 4344679079 scopus 로고    scopus 로고
    • Bone cancer pain: The effects of the bisphosphonate alendronate on pain, skeletal remodeling, tumor growth and tumor necrosis
    • Sevcik MA, Luger NM, Mach DB, Sabino MA, Peters CM, et al. (2004) Bone cancer pain: the effects of the bisphosphonate alendronate on pain, skeletal remodeling, tumor growth and tumor necrosis. Pain 111: 169-180.
    • (2004) Pain , vol.111 , pp. 169-180
    • Sevcik, M.A.1    Luger, N.M.2    Mach, D.B.3    Sabino, M.A.4    Peters, C.M.5
  • 43
    • 42349098792 scopus 로고    scopus 로고
    • Alendronate decreases orthotopic PC-3 prostate tumor growth and metastasis to prostate-draining lymph nodes in nude mice
    • Tuomela JM, Valta MP, Vaananen K, Harkonen PL (2008) Alendronate decreases orthotopic PC-3 prostate tumor growth and metastasis to prostate-draining lymph nodes in nude mice. BMC Cancer 8: 81.
    • (2008) BMC Cancer , vol.8 , pp. 81
    • Tuomela, J.M.1    Valta, M.P.2    Vaananen, K.3    Harkonen, P.L.4
  • 44
    • 33947540949 scopus 로고    scopus 로고
    • Alendronate induces antimigratory effects and inhibition of neutral phosphatases in UMR106 osteosarcoma cells
    • Molinuevo MS, Bruzzone L, Cortizo AM (2007) Alendronate induces antimigratory effects and inhibition of neutral phosphatases in UMR106 osteosarcoma cells. Eur J Pharmacol 562: 28-33.
    • (2007) Eur J Pharmacol , vol.562 , pp. 28-33
    • Molinuevo, M.S.1    Bruzzone, L.2    Cortizo, A.M.3
  • 45
    • 12544258226 scopus 로고    scopus 로고
    • Alendronate inhibits intraperitoneal dissemination in in vivo ovarian cancer model
    • Hashimoto K, Morishige K, Sawada K, Tahara M, Kawagishi R, et al. (2005) Alendronate inhibits intraperitoneal dissemination in in vivo ovarian cancer model. Cancer Res 65: 540-545.
    • (2005) Cancer Res , vol.65 , pp. 540-545
    • Hashimoto, K.1    Morishige, K.2    Sawada, K.3    Tahara, M.4    Kawagishi, R.5
  • 46
    • 33846483160 scopus 로고    scopus 로고
    • Alendronate suppresses tumor angiogenesis by inhibiting Rho activation of endothelial cells
    • Hashimoto K, Morishige K, Sawada K, Tahara M, Shimizu S, et al. (2007) Alendronate suppresses tumor angiogenesis by inhibiting Rho activation of endothelial cells. Biochem Biophys Res Commun 354: 478-484.
    • (2007) Biochem Biophys Res Commun , vol.354 , pp. 478-484
    • Hashimoto, K.1    Morishige, K.2    Sawada, K.3    Tahara, M.4    Shimizu, S.5
  • 47
    • 33947109369 scopus 로고    scopus 로고
    • Bisphosphonates: Mode of action and pharmacology
    • Russell RG (2007) Bisphosphonates: mode of action and pharmacology. Pediatrics 119 Suppl 2: S150-162.
    • (2007) Pediatrics , vol.119 , Issue.SUPPL. 2
    • Russell, R.G.1
  • 48
    • 1942454714 scopus 로고    scopus 로고
    • Alendronate regulates cell invasion and MMP-2 secretion in human osteosarcoma cell lines
    • Cheng YY, Huang L, Lee KM, Li K, Kumta SM (2004) Alendronate regulates cell invasion and MMP-2 secretion in human osteosarcoma cell lines. Pediatr Blood Cancer 42: 410-415.
    • (2004) Pediatr Blood Cancer , vol.42 , pp. 410-415
    • Cheng, Y.Y.1    Huang, L.2    Lee, K.M.3    Li, K.4    Kumta, S.M.5
  • 49
    • 38349023103 scopus 로고    scopus 로고
    • Cathepsins and osteosarcoma: Expression analysis identifies cathepsin K as an indicator of metastasis
    • Husmann K, Muff R, Bolander ME, Sarkar G, Born W, et al. (2008) Cathepsins and osteosarcoma: Expression analysis identifies cathepsin K as an indicator of metastasis. Mol Carcinog 47: 66-73.
    • (2008) Mol Carcinog , vol.47 , pp. 66-73
    • Husmann, K.1    Muff, R.2    Bolander, M.E.3    Sarkar, G.4    Born, W.5
  • 52
    • 46449134613 scopus 로고    scopus 로고
    • Phase I/ II study of biweekly paclitaxel and radiation in androgen-ablated locally advanced prostate cancer
    • Sanfilippo NJ, Taneja SS, Chachoua A, Lepor H, Formenti SC (2008) Phase I/ II study of biweekly paclitaxel and radiation in androgen-ablated locally advanced prostate cancer. J Clin Oncol 26: 2973-2978.
    • (2008) J Clin Oncol , vol.26 , pp. 2973-2978
    • Sanfilippo, N.J.1    Taneja, S.S.2    Chachoua, A.3    Lepor, H.4    Formenti, S.C.5
  • 53
    • 0037097705 scopus 로고    scopus 로고
    • Spectrophotometric determination of alendronate in pharmaceutical formulations via complex formation with Fe(III) ions
    • Kuljanin J, Jankovic I, Nedeljkovic J, Prstojevic D, Marinkovic V (2002) Spectrophotometric determination of alendronate in pharmaceutical formulations via complex formation with Fe(III) ions. J Pharm Biomed Anal 28: 1215-1220.
    • (2002) J Pharm Biomed Anal , vol.28 , pp. 1215-1220
    • Kuljanin, J.1    Jankovic, I.2    Nedeljkovic, J.3    Prstojevic, D.4    Marinkovic, V.5
  • 54
    • 0030031898 scopus 로고    scopus 로고
    • Expression of vascular permeability factor/vascular endothelial growth factor by melanoma cells increases tumor growth, angiogenesis, and experimental metastasis
    • Claffey KP, Brown LF, del Aguila LF, Tognazzi K, Yeo KT, et al. (1996) Expression of vascular permeability factor/vascular endothelial growth factor by melanoma cells increases tumor growth, angiogenesis, and experimental metastasis. Cancer Res 56: 172-181.
    • (1996) Cancer Res , vol.56 , pp. 172-181
    • Claffey, K.P.1    Brown, L.F.2    del Aguila, L.F.3    Tognazzi, K.4    Yeo, K.T.5
  • 55
    • 84940142489 scopus 로고
    • Vascular reactions to histamine, histamine-liberator and leukotaxine in the skin of guinea-pigs
    • Miles AA, Miles EM (1952) Vascular reactions to histamine, histamine-liberator and leukotaxine in the skin of guinea-pigs. J Physiol 118: 228-257.
    • (1952) J Physiol , vol.118 , pp. 228-257
    • Miles, A.A.1    Miles, E.M.2
  • 56
    • 0026083903 scopus 로고
    • Tumor angiogenesis and metastasis-correlation in invasive breast carcinoma
    • Weidner N, Semple JP, Welch WR, Folkman J (1991) Tumor angiogenesis and metastasis-correlation in invasive breast carcinoma. N Engl J Med 324: 1-8.
    • (1991) N Engl J Med , vol.324 , pp. 1-8
    • Weidner, N.1    Semple, J.P.2    Welch, W.R.3    Folkman, J.4
  • 57
    • 0035816143 scopus 로고    scopus 로고
    • Polymer-drug conjugates, PDEPT and PELT: Basic principles for design and transfer from the laboratory to clinic
    • Duncan R, Gac-Breton S, Keane R, Musila R, Sat YN, et al. (2001) Polymer-drug conjugates, PDEPT and PELT: basic principles for design and transfer from the laboratory to clinic. J Control Release 74: 135-146.
    • (2001) J Control Release , vol.74 , pp. 135-146
    • Duncan, R.1    Gac-Breton, S.2    Keane, R.3    Musila, R.4    Sat, Y.N.5
  • 58
    • 0036842215 scopus 로고    scopus 로고
    • Vascular permeability factor/vascular endothelial growth factor: A critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy
    • Dvorak HF (2002) Vascular permeability factor/vascular endothelial growth factor: a critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy. J Clin Oncol 20: 4368-4380.
    • (2002) J Clin Oncol , vol.20 , pp. 4368-4380
    • Dvorak, H.F.1
  • 59
    • 33747117688 scopus 로고    scopus 로고
    • Hydroxybisphosphonate-containing polymeric drug-delivery systems designed for targeting into bone tissue
    • Hrubý M, Etrych T, Kučka J, Forsterová M, Ulbrich K (2006) Hydroxybisphosphonate-containing polymeric drug-delivery systems designed for targeting into bone tissue. Journal of Applied Polymer Science 101: 3192-3201.
    • (2006) Journal of Applied Polymer Science , vol.101 , pp. 3192-3201
    • Hrubý, M.1    Etrych, T.2    Kučka, J.3    Forsterová, M.4    Ulbrich, K.5
  • 60
    • 0141606725 scopus 로고    scopus 로고
    • Synthesis and evaluation of water-soluble polymeric bone-targeted drug delivery systems
    • Wang D, Miller S, Sima M, Kopečková P, Kopeček J (2003) Synthesis and evaluation of water-soluble polymeric bone-targeted drug delivery systems. Bioconjug Chem 14: 853-859.
    • (2003) Bioconjug Chem , vol.14 , pp. 853-859
    • Wang, D.1    Miller, S.2    Sima, M.3    Kopečková, P.4    Kopeček, J.5
  • 61
    • 4644259034 scopus 로고    scopus 로고
    • Current strategy of chemotherapy for reflactory bone and soft tissue sarcomas]
    • Chuman H (2004) [Current strategy of chemotherapy for reflactory bone and soft tissue sarcomas]. Gan To Kagaku Ryoho 31: 1331-1339.
    • (2004) Gan To Kagaku Ryoho , vol.31 , pp. 1331-1339
    • Chuman, H.1
  • 63
    • 0028248444 scopus 로고
    • A polymeric drug delivery system for the simultaneous delivery of drugs activatable by enzymes and/or light
    • Krinick NL, Sun Y, Joyner D, Spikes JD, Straight RC, et al. (1994) A polymeric drug delivery system for the simultaneous delivery of drugs activatable by enzymes and/or light. J Biomat Sci Polym Ed 5: 303-324.
    • (1994) J Biomat Sci Polym Ed , vol.5 , pp. 303-324
    • Krinick, N.L.1    Sun, Y.2    Joyner, D.3    Spikes, J.D.4    Straight, R.C.5
  • 64
    • 9444268102 scopus 로고    scopus 로고
    • Combination chemotherapy and photodynamic therapy with N-(2-hydroxypropyl) methacrylamide copolymer-bound anticancer drugs inhibit human ovarian carcinoma heterotransplanted in nude mice
    • Peterson CM, Lu JM, Sun Y, Peterson CA, Shiah JG, et al. (1996) Combination chemotherapy and photodynamic therapy with N-(2-hydroxypropyl) methacrylamide copolymer-bound anticancer drugs inhibit human ovarian carcinoma heterotransplanted in nude mice. Cancer Res 56: 3980-3985.
    • (1996) Cancer Res , vol.56 , pp. 3980-3985
    • Peterson, C.M.1    Lu, J.M.2    Sun, Y.3    Peterson, C.A.4    Shiah, J.G.5
  • 65
    • 0034059468 scopus 로고    scopus 로고
    • Antitumor activity of N-(2-hydroxypropyl) methacrylamide copolymer-mesochlorin e6 and adriamycin conjugates in combination treatments
    • Shiah JG, Sun Y, Peterson CM, Straight RC, Kopeček J (2000) Antitumor activity of N-(2-hydroxypropyl) methacrylamide copolymer-mesochlorin e6 and adriamycin conjugates in combination treatments. Clin Cancer Res 6: 1008-1015.
    • (2000) Clin Cancer Res , vol.6 , pp. 1008-1015
    • Shiah, J.G.1    Sun, Y.2    Peterson, C.M.3    Straight, R.C.4    Kopeček, J.5
  • 66
    • 21244493239 scopus 로고    scopus 로고
    • Polymer therapeutics designed for a combination therapy of hormone-dependent cancer
    • Vicent MJ, Greco F, Nicholson RI, Paul A, Griffiths PC, et al. (2005) Polymer therapeutics designed for a combination therapy of hormone-dependent cancer. Angew Chem Int Ed Engl 44: 4061-4066.
    • (2005) Angew Chem Int Ed Engl , vol.44 , pp. 4061-4066
    • Vicent, M.J.1    Greco, F.2    Nicholson, R.I.3    Paul, A.4    Griffiths, P.C.5
  • 67
    • 33846549188 scopus 로고    scopus 로고
    • Investigating the mechanism of enhanced cytotoxicity of HPMA copolymer-Dox-AGM in breast cancer cells
    • Greco F, Vicent MJ, Gee S, Jones AT, Gee J, et al. (2007) Investigating the mechanism of enhanced cytotoxicity of HPMA copolymer-Dox-AGM in breast cancer cells. J Control Release 117: 28-39.
    • (2007) J Control Release , vol.117 , pp. 28-39
    • Greco, F.1    Vicent, M.J.2    Gee, S.3    Jones, A.T.4    Gee, J.5
  • 68
    • 11844254414 scopus 로고    scopus 로고
    • Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy
    • Jain RK (2005) Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. Science 307: 58-62.
    • (2005) Science , vol.307 , pp. 58-62
    • Jain, R.K.1
  • 69
    • 65349154064 scopus 로고    scopus 로고
    • Mourad JJ, des Guetz G, Debbabi H, Levy BI (2007) Blood pressure rise following angiogenesis inhibition by bevacizumab. A crucial role for microcirculation. Ann Oncol.
    • Mourad JJ, des Guetz G, Debbabi H, Levy BI (2007) Blood pressure rise following angiogenesis inhibition by bevacizumab. A crucial role for microcirculation. Ann Oncol.
  • 70
    • 0037208589 scopus 로고    scopus 로고
    • Phase II, randomized trial comparing bevacizumab plus fluorouracil (FU)/leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer
    • Kabbinavar F, Hurwitz HI, Fehrenbacher L, Meropol NJ, Novotny WF, et al. (2003) Phase II, randomized trial comparing bevacizumab plus fluorouracil (FU)/leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer. J Clin Oncol 21: 60-65.
    • (2003) J Clin Oncol , vol.21 , pp. 60-65
    • Kabbinavar, F.1    Hurwitz, H.I.2    Fehrenbacher, L.3    Meropol, N.J.4    Novotny, W.F.5
  • 71
    • 18744377487 scopus 로고    scopus 로고
    • Bevacizumab in combination chemotherapy for colorectal and other cancers
    • Motl S (2005) Bevacizumab in combination chemotherapy for colorectal and other cancers. Am J Health Syst Pharm 62: 1021-1032.
    • (2005) Am J Health Syst Pharm , vol.62 , pp. 1021-1032
    • Motl, S.1
  • 73
    • 27644568995 scopus 로고    scopus 로고
    • The inhibitory effect of alendronate, a nitrogen-containing bisphosphonate on the PI3K-Akt-NFkappaB pathway in osteosarcoma cells
    • Inoue R, Matsuki NA, Jing G, Kanematsu T, Abe K, et al. (2005) The inhibitory effect of alendronate, a nitrogen-containing bisphosphonate on the PI3K-Akt-NFkappaB pathway in osteosarcoma cells. Br J Pharmacol 146: 633-641.
    • (2005) Br J Pharmacol , vol.146 , pp. 633-641
    • Inoue, R.1    Matsuki, N.A.2    Jing, G.3    Kanematsu, T.4    Abe, K.5
  • 74
    • 0017708682 scopus 로고
    • Metastatic osteosarcoma to lung: A clinicopathologic study of surgical biopsies and resections
    • Dunn D, Dehner LP (1977) Metastatic osteosarcoma to lung: a clinicopathologic study of surgical biopsies and resections. Cancer 40: 3054-3064.
    • (1977) Cancer , vol.40 , pp. 3054-3064
    • Dunn, D.1    Dehner, L.P.2
  • 75
    • 45549104510 scopus 로고    scopus 로고
    • Gomez Font R, Martinez Garcia ML, Olmos Martinez JM (2008) Osteochemonecrosis of the jaws due to bisphosphonate treatments. Update. Med Oral Patol Oral Cir Bucal 13: E318-324.
    • Gomez Font R, Martinez Garcia ML, Olmos Martinez JM (2008) Osteochemonecrosis of the jaws due to bisphosphonate treatments. Update. Med Oral Patol Oral Cir Bucal 13: E318-324.


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