Altered γ-catenin expression correlates with poor survival in patients with bladder cancer

Journal of Urology

Volumn 160, Issue 5, 1998, Pages 1889-1893

  Syrigos, K N ^a,b   Harrington, K ^a   Waxman, J ^a   Krausz, T ^a   Pignatelli, M ^a  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

^b Kifisias 40 and Arkadias ^*  (Greece)

Author keywords

Adhesion; E cadherin catenins complex; Prognostic markers

Indexed keywords

BETA CATENIN;

ARTICLE; BLADDER CANCER; BLADDER EPITHELIUM; CANCER STAGING; CANCER SURVIVAL; COMPLEX FORMATION; HUMAN; HUMAN TISSUE; IMMUNOPEROXIDASE STAINING; PRIORITY JOURNAL; PROGNOSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; RECEPTOR BINDING; TRANSITIONAL CELL CARCINOMA; TUMOR LOCALIZATION;

EID: 0345411418     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-5347(01)62438-8     Document Type: Article

References (30)

1. Heiken, J. P., Forman, H. P. and Brown, J. J.: Neoplasms of the bladder, prostate and testis. Radiol. Clin. North. Am., 32: 81, 1994.
2. Narayana, A. S., Loening, S. A., Slymen, D. J. and Culp, D. A.: Bladder cancer: factors affecting survival. J. Urol., 130: 56, 1983.
3. Abel, P. D., Henderson, D., Bennett, M. K., Hall, R. R. and Williams, G.: Differing interpretations by pathologist of the pT category and grade of transitional cell cancer of the bladder. Br. J. Urol., 62: 339, 1988.
4. Ooms, E. C., Anderson, W. A., Alons, C. L., Boon, M. E. and Veldhuizen, R. W.: Analysis of the performance of pathologists in the grading of bladder tumors. Hum. Pathol., 14: 140, 1983.
5. Takeichi, M.: Cadherin cell adhesion receptors as a morphogenetic regulator. Science, 251: 1451, 1991.
6. Oka, H., Shiozaki, H., Kobayashi, K., Inoue, M., Tahara, H., Kobayashi, T., Takatsuka, Y., Matsuyoshi, N., Hirano, S. and Takeichi, M.: Expression of E-cadherin cell adhesion molecules in human breast cancer tissues and its relationship to metastasis. Cancer Res., 53: 1696, 1993.
7. Nigam, A. K., Savage, F. J., Boulos, P. B., Stamp, G. W. H., Liu, D. and Pignatelli, M.: Loss of cell-cell and cell-matrix adhesion molecules in colorectal cancer. Br. J. Cancer, 68: 507, 1993.
8. Umbas, R., Schalken, J. A., Aalders, T. W., Carter, B. S., Karthaus, H. F., Schaafsma, H. E., Debruyne, M. J. and Isaacs, W. B.: Expression of the cellular adhesion molecule E-cadherin is reduced or absent in high grade prostate cancer. Cancer Res., 52: 5104, 1992.
9. Pignatelli, M., Ansari, T. W., Gunter, P., Liu, D., Hirano, S., Takeichi, M., Kloppel, G. and Lemoine, N.: Loss of membranous E-cadherin expression in pancreatic cancer: correlation with lymph node metastasis, high grade and advanced stage. J. Pathol., 174: 243, 1994.
10. Schipper, J. H., Frixen, U. H., Behrens, J., Unger, A., Jahnke, K. and Birchmeier, W.: E-cadherin expression in squamous cell carcinomas of head and neck: inverse correlation with tumor dedifferentiation and lymph node metastasis. Cancer Res., 51: 6328, 1991.
11. Syrigos, K. N., Krausz, T., Waxman, J., Pandha, H., Rowlinson-Busza, G., Verne, J., Epenetos, A. A. and Pignatelli, M.: E-cadherin expression in bladder cancer using formalin-fixed, paraffin-embedded tissues: correlation with histopathological grade and tumour stage and survival. Int. J. Cancer, 64: 367, 1995.
12. Bringuier, P. P., Umbas, R., Schaafsma, E., Karthaus, H. F. M., deBruyne, F. M. J. and Schalken, J. A.: Decreased E-cadherin immunoreactivity correlates with poor survival in patients with bladder tumors. Cancer Res., 53: 3241, 1993.
13. Frixen, V., Behrens, J., Sachs, M., Eberle, G., Voss, B., Warda, A., Lochner, D. and Birchmeier, W.: E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells. J. Cell Biol., 113: 173, 1991.
14. Nagafuchi, A., Takeichi, M. and Tsukita, S.: The 102 kDa cadherin-associated protein: similarity to vinculin and post-transcriptional regulation of expression. Cell, 65: 849, 1991.
15. Tsukita, S. H., Tsukita, S. A., Nagafuchi, A. and Yonemura, S.: Molecular linkage between cadherins and actin filaments in cell-cell adherens junctions. Curr. Opin. Cell Biol., 4: 834, 1992.
16. Nagafuchi, A. and Takeichi, M.: Transmembrane control of cadherin mediated cell adhesion: a 94 kDa protein functionally associated with a specific region of the cytoplasmic domain of E-cadherin. Cell Regul., 1: 37, 1989.
17. Ozawa, M., Ringwald, M. and Kemler, R.: Uvomorulin-catenin complex formation is regulated by a specific domain in the cytoplasmic region of the cell adhesion molecule. Proc. Natl. Acad. Sci. USA, 87: 4246, 1990.
18. Nathke, I., Hink, L., Swedlow, J. R., Papkoff, J. and Nelson, W. J.: Defining interactions and distributions of cadherin and catenin complexes in polarised epithelial cells. J. Cell Biol., 125: 1341, 1994.
19. Nathke, I., Hinck, L. and Nelson, J.: Epithelial cell adhesion and development of cell surface polarity: possible mechanisms for modulation of cadherin function, organisation and distribution. J. Cell Sci. Suppl., 17: 139, 1993.
20. Peifer, M.: Cancer, catenins and cuticle pattern: a complex connection. Science, 262: 1667, 1993.
21. Hirano, S., Kimoto, N., Shimoyama, Y., Hirohashi, S. and Takeichi, M.: Identification of a neutral alpha-catenin as a key regulator of cadherin function and multicellular organisation. Cell, 70: 293, 1992.
22. Gumbiner, B. M. and McCrea, P. D.: Catenins as mediators of the cytoplasmic functions of cadherins. J. Cell Sci. Suppl., 17: 155, 1993.
23. Ozawa, M., Nuruki, K., Toyoyama, H. and Ohi, Y.: Cloning of an alternative form of plakoglobin (gamma-catenin) lacking the fourth armadillo repeat. J. Biochem. Tokyo, 118: 836, 1995.
24. Mostofi, F. K., Sobin, L. H. and Torloni, H.: Histological typing of urinary bladder tumours. In: International Histological Classification of Tumours, 10. Geneva: World Health Organisation, 1973.
25. Hermanek, P. and Sobin, L. H.: UICC: TNM Classification of Malignant Tumours. Berlin: Springer-Verlag, pp. 65-67, 1987.
26. Shiozaki, H., Tahara, H., Oka, H., Miyata, M., Kobayashi, K. and Tamura, S.: Expression of immunoreactive E-cadherin adhesion molecules in human cancers. Am. J. Pathol., 139: 17, 1991.
27. Behrens, J.: Cell contacts, differentiation and invasiveness of epithelial cells. Invasion Metast., 14: 61, 1994.
28. Rebel, J. M., Thijssen, C. D., Vermey, M., Delouvee, A., Zwarthoff, E. C. and Van der Kwast, TH.: E-cadherin expression determines the mode of replacement of normal urothelium by human bladder carcinoma cell lines. Cancer Res., 54: 5488, 1994.
29. Ross, J. S., del Rosario, A. D., Figge, H. L., Sheehan, C., Fisher, H. A. and Bui, H. X.: E-cadherin expression in papillary transitional cell carcinoma of the urinary bladder. Hum. Pathol., 26: 940, 1995.
30. cas) in bladder tumors. Cancer Res., 56: 4154, 1996.