A homeodomain protein code specifies progenitor cell identity and neuronal fate in the ventral neural tube

Cell

Volumn 101, Issue 4, 2000, Pages 435-445

  Briscoe, James ^a   Pierani, Alessandra ^a   Jessell, Thomas M ^a   Ericson, Johan ^a,b  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

HOMEODOMAIN PROTEIN; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; MITOSIS; NERVE CELL; NEURAL TUBE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DETERMINATION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ANIMALIA; ERINACEIDAE;

EID: 0034640087     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)80853-3     Document Type: Article

References (48)

1. Requirement for the homeobox gene Hb9 in the consolidation of motor neuron identity
2. Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signaling
3. Transducing the Dpp morphogen gradient in the wing of Drosophila: Regulation of Dpp targets by brinker
4. Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function
5. Combinatorial codes in signaling and synergy: Lessons from pituitary development
6. Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice
7. Two critical periods of Sonic Hedgehog signaling required for the specification of motor neuron identity
8. Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signaling
9. Graded sonic hedgehog signaling and the specification of cell fate in the ventral neural tube
10. Progenitor dispersal and the origin of early neuronal phenotypes in the chick embryo spinal cord
11. Coelom formation: Binary decision of the lateral plate mesoderm is controlled by the ectoderm
12. Signals from the notochord and floor plate regulate the region-specific expression of two Pax genes in the developing spinal cord
13. A series of normal stages in the development of the chick embryo
14. An anteroposterior Dorsal gradient in the Drosophila embryo
15. Adaptor plasmids simplify the insertion of foreign DNA into helper-independent retroviral vectors
16. Transducing Hedgehog: The story so far
17. The Drosophila gene brinker reveals a novel mechanism of Dpp target gene regulation
18. Spatial regulation of the gap gene giant during Drosophila development
19. Mediation of Sonic hedgehog-induced expression of COUP-TFII by a protein phosphatase
20. Behavior of neuroepithelial cells during closure of neural tube
21. Morphogens, compartments, and pattern: Lessons from Drosophila?
22. Migratory paths of neurons and glia in the embryonic chick spinal cord
23. Expression of ptc and gli genes in talpid3 suggests bifurcation in Shh pathway
24. Patterning the vertebrate neuraxis
25. Pax3 and Pax7 are expressed in commissural neurons and restrict ventral neuronal identity in the spinal cord
26. Distribution of Sonic hedgehog peptides in the developing chick and mouse embryo
27. Gli2 is required for induction of floor plate and adjacent cells, but not most ventral neurons in the mouse central nervous system
28. Activin as a morphogen in Xenopus mesoderm induction
29. Brinker is a target of Dpp in Drosophila that negatively regulates Dpp-dependent genes
30. Manipulating gene expression with replication-competent retroviruses
31. Comparison of three nonviral transfection methods for foreign gene expression in early chicken embryos in ovo
32. Nkx2.9 is a novel homeobox transcription factor which demarcates ventral domains in the developing mouse CNS
33. Gradual refinement of activin-induced thresholds requires protein synthesis
34. A sonic hedgehog-independent, retinoid-activated pathway of neurogenesis in the ventral spinal cord
35. Control of anteroposterior and dorsoventral domains of Nkx-6.1 gene expression relative to other Nkx genes during vertebrate CNS development
36. Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of sonic hedgehog autoproteolysis
37. Sonic hedgehog regulates proliferation and inhibits differentiation of CNS precursor cells
38. Gli proteins and Hedgehog signaling: Development and cancer
39. A single protocol to detect transcripts of various types and expression levels in neural tissue and cultured cells: In situ hybridization using digoxigenin-labelled cRNA probes
40. LIM homeodomain factors Lhx3 and Lhx4 assign subtype identities for motor neurons
41. Mesoderm-inducing factors and mesodermal patterning
42. Control of Drosophila body pattern by the hunchback morphogen gradient
43. Specification of motor neuron identity by the MNR2 homeodomain protein
44. Positional information and the spatial pattern of cellular differentiation
45. Two distinct mechanisms for differential positioning of gene expression borders involving the Drosophila gap protein giant
46. In vivo cell sorting in complementary segmental domains mediated by Eph receptors and ephrins
47. Control of cell pattern in the neural tube: Motor neuron induction by diffusible factors from notochord and floor plate