-
1
-
-
0034721665
-
Transducing the hedgehog signal
-
Kalderon D: Transducing the hedgehog signal. Cell 2000, 103:371-374.
-
(2000)
Cell
, vol.103
, pp. 371-374
-
-
Kalderon, D.1
-
2
-
-
0036778132
-
Hedgehog signal transduction: Recent findings
-
Nybakken K, Perrimon N: Hedgehog signal transduction: recent findings. Curr Opin Genet Dev 2002, 12:503-511.
-
(2002)
Curr. Opin. Genet. Dev.
, vol.12
, pp. 503-511
-
-
Nybakken, K.1
Perrimon, N.2
-
3
-
-
0029843937
-
Regulation of Patched by Sonic hedgehog in the developing neural tube
-
Marigo V, Tabin CJ: Regulation of Patched by Sonic hedgehog in the developing neural tube. P Natl Acad Sci USA 1996, 93:9346-9351.
-
(1996)
P. Natl. Acad. Sci. USA
, vol.93
, pp. 9346-9351
-
-
Marigo, V.1
Tabin, C.J.2
-
4
-
-
0033580269
-
Vertebrate hedgehog signalling modulated by induction of a Hedgehog-binding protein
-
Chuang PT, McMahon AP: Vertebrate hedgehog signalling modulated by induction of a Hedgehog-binding protein. Nature 1999, 397:617-621.
-
(1999)
Nature
, vol.397
, pp. 617-621
-
-
Chuang, P.T.1
McMahon, A.P.2
-
5
-
-
0035822098
-
A freely diffusible form of Sonic hedgehog mediates longrange signalling
-
Zeng X, Goetz JA, Suber LM, Scott WJ, Schreiner CM, Robbins DM: A freely diffusible form of Sonic hedgehog mediates longrange signalling. Nature 2001, 411:716-720.
-
(2001)
Nature
, vol.411
, pp. 716-720
-
-
Zeng, X.1
Goetz, J.A.2
Suber, L.M.3
Scott, W.J.4
Schreiner, C.M.5
Robbins, D.M.6
-
6
-
-
0034985595
-
Indian hedgehog activates hematopoiesis and vasculogenesis and can respecify prospective neurectodermal cell fate in the mouse embryo
-
Dyer MA, Farrington SM, Mohn D, Munday JR, Baron MH: Indian hedgehog activates hematopoiesis and vasculogenesis and can respecify prospective neurectodermal cell fate in the mouse embryo. Development 2001, 128:1717-1730.
-
(2001)
Development
, vol.128
, pp. 1717-1730
-
-
Dyer, M.A.1
Farrington, S.M.2
Mohn, D.3
Munday, J.R.4
Baron, M.H.5
-
7
-
-
0034960583
-
The morphogen Sonic hedgehog is an indirect angiogenic agent upregulating two families of angiogenic growth factors
-
Pola R, Ling LE, Silver M, Corbley MJ, Kearney M, Pepinsky RB, Shapiro R, Taylor FR, Baker DP, Asahara T, Isner JM: The morphogen Sonic hedgehog is an indirect angiogenic agent upregulating two families of angiogenic growth factors. Nature Med 2001, 7:706-711.
-
(2001)
Nature Med.
, vol.7
, pp. 706-711
-
-
Pola, R.1
Ling, L.E.2
Silver, M.3
Corbley, M.J.4
Kearney, M.5
Pepinsky, R.B.6
Shapiro, R.7
Taylor, F.R.8
Baker, D.P.9
Asahara, T.10
Isner, J.M.11
-
8
-
-
0042711211
-
Postnatal recapitulation of embryonic hedgehog pathway in response to skeletal muscle ischemia
-
Pola R, Ling LE, Aprahamian TR, Barban E, Bosch-Marce M, Curry C, Corbley M, Kearney M, Isner JM, Losordo DW: Postnatal recapitulation of embryonic hedgehog pathway in response to skeletal muscle ischemia. Circulation 2003, 108:479-485.
-
(2003)
Circulation
, vol.108
, pp. 479-485
-
-
Pola, R.1
Ling, L.E.2
Aprahamian, T.R.3
Barban, E.4
Bosch-Marce, M.5
Curry, C.6
Corbley, M.7
Kearney, M.8
Isner, J.M.9
Losordo, D.W.10
-
9
-
-
0036339732
-
Hedgehog is required for murine yolk sac angiogenesis
-
Byrd N, Becker S, Maye P, Narasimhaiah R, St-Jacques B, Zhang X, McMahon J, McMahon A, Grabel L: Hedgehog is required for murine yolk sac angiogenesis. Development 2002, 129:361-372.
-
(2002)
Development
, vol.129
, pp. 361-372
-
-
Byrd, N.1
Becker, S.2
Maye, P.3
Narasimhaiah, R.4
St-Jacques, B.5
Zhang, X.6
McMahon, J.7
McMahon, A.8
Grabel, L.9
-
10
-
-
0036559186
-
Gli and Hedgehog in cancer: Tumours, embryos and stem cells
-
Ruiz i Altaba A, Sanchez P, Dahmane N: Gli and Hedgehog in cancer: tumours, embryos and stem cells. Nature Reviews 2002, 2:361-372.
-
(2002)
Nature Reviews
, vol.2
, pp. 361-372
-
-
Ruiz i Altaba, A.1
Sanchez, P.2
Dahmane, N.3
-
11
-
-
15844386165
-
Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome
-
Hahn H, Wicking C, Zaphiropoulos PG, Gailani MR, Shanley S, Chidambaram A, Vorechovsky I, Holmberg E, Unden AB, Gillies S, Negus K, Smyth I, Pressman C, Leffell DJ, Gerrard B, Goldstein AM, Dean M, Toftgard R, Chenevix-Trench G, Wainwright B, Bale AE: Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome. Cell 1996, 85:841-851.
-
(1996)
Cell
, vol.85
, pp. 841-851
-
-
Hahn, H.1
Wicking, C.2
Zaphiropoulos, P.G.3
Gailani, M.R.4
Shanley, S.5
Chidambaram, A.6
Vorechovsky, I.7
Holmberg, E.8
Unden, A.B.9
Gillies, S.10
Negus, K.11
Smyth, I.12
Pressman, C.13
Leffell, D.J.14
Gerrard, B.15
Goldstein, A.M.16
Dean, M.17
Toftgard, R.18
Chenevix-Trench, G.19
Wainwright, B.20
Bale, A.E.21
more..
-
12
-
-
0023091971
-
Identification of an amplified, highly expressed gene in a human glioma
-
Kinzler KW, Bigner SH, Bigner DD, Trent JM, Law ML, O'Brien SJ, Wong AJ, Vogelstein B: Identification of an amplified, highly expressed gene in a human glioma. Science 1987, 236:70-73.
-
(1987)
Science
, vol.236
, pp. 70-73
-
-
Kinzler, K.W.1
Bigner, S.H.2
Bigner, D.D.3
Trent, J.M.4
Law, M.L.5
O'Brien, S.J.6
Wong, A.J.7
Vogelstein, B.8
-
13
-
-
0242268525
-
Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours
-
Berman DM, Karhadkar SS, Maitra A, Montes De Oca R, Gerstenblith MR, Briggs K, Parker AR, Shimada Y, Eshleman JR, Watkins DN, Beachy PA: Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours. Nature 2003, 425: 46-851.
-
(2003)
Nature
, vol.425
, pp. 846-851
-
-
Berman, D.M.1
Karhadkar, S.S.2
Maitra, A.3
Montes De Oca, R.4
Gerstenblith, M.R.5
Briggs, K.6
Parker, A.R.7
Shimada, Y.8
Eshleman, J.R.9
Watkins, D.N.10
Beachy, P.A.11
-
14
-
-
0242270878
-
Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis
-
Thayer SP, di Magliano MP, Heiser PW, Nielsen CM, Roberts DJ, Lauwers GY, Qi YP, Gysin S, Fernandez-del Castillo C, Yajnik V, Antoniu B, McMahon M, Warshaw AL, Hebrok M: Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis. Nature 2003, 425:851-856.
-
(2003)
Nature
, vol.425
, pp. 851-856
-
-
Thayer, S.P.1
di Magliano, M.P.2
Heiser, P.W.3
Nielsen, C.M.4
Roberts, D.J.5
Lauwers, G.Y.6
Qi, Y.P.7
Gysin, S.8
Fernandez-del Castillo, C.9
Yajnik, V.10
Antoniu, B.11
McMahon, M.12
Warshaw, A.L.13
Hebrok, M.14
-
15
-
-
0242669237
-
Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer
-
Watkins DN, Berman DM, Burkholder SG, Wang B, Beachy PA, Baylin SB: Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer. Nature 2003, 422:313-317.
-
(2003)
Nature
, vol.422
, pp. 313-317
-
-
Watkins, D.N.1
Berman, D.M.2
Burkholder, S.G.3
Wang, B.4
Beachy, P.A.5
Baylin, S.B.6
-
17
-
-
0037376877
-
Angiogenesis and apoptosis
-
Folkman J: Angiogenesis and apoptosis. Semin Cancer Biol 2003, 13:159-167.
-
(2003)
Semin. Cancer Biol.
, vol.13
, pp. 159-167
-
-
Folkman, J.1
-
18
-
-
0027487871
-
Angiogenesis inhibitor TNP-470 (AGM-1470) potently inhibits the tumor growth of hormone-independent human breast and prostate carcinoma cell lines
-
Yamaoka M, Yamamoto T, Ikeyama S, Sudo K, Fujita T: Angiogenesis inhibitor TNP-470 (AGM-1470) potently inhibits the tumor growth of hormone-independent human breast and prostate carcinoma cell lines. Cancer Res 1993, 53:5233-5236.
-
(1993)
Cancer Res.
, vol.53
, pp. 5233-5236
-
-
Yamaoka, M.1
Yamamoto, T.2
Ikeyama, S.3
Sudo, K.4
Fujita, T.5
-
19
-
-
0037102369
-
ZD6474 Inhibits Vascular Endothelial Growth Factor Signaling, Angiogenesis, and Tumor Growth following Oral Administration
-
Wedge SR, Ogilvie DJ, Dukes M, Kendrew J, Chester R, Jackson JA, Boffey SJ, Valentine PJ, Curwen JO, Musgrove HL, Graham GA, Hughes GD, Thomas AP, Stokes ESE, Curry B, Richmond GHP, Wadsworth PF, Bigley AL, Hennequin LF: ZD6474 Inhibits Vascular Endothelial Growth Factor Signaling, Angiogenesis, and Tumor Growth following Oral Administration. Cancer Res 2002, 62:4645-4655.
-
(2002)
Cancer Res.
, vol.62
, pp. 4645-4655
-
-
Wedge, S.R.1
Ogilvie, D.J.2
Dukes, M.3
Kendrew, J.4
Chester, R.5
Jackson, J.A.6
Boffey, S.J.7
Valentine, P.J.8
Curwen, J.O.9
Musgrove, H.L.10
Graham, G.A.11
Hughes, G.D.12
Thomas, A.P.13
Stokes, E.S.E.14
Curry, B.15
Richmond, G.H.P.16
Wadsworth, P.F.17
Bigley, A.L.18
Hennequin, L.F.19
-
20
-
-
0030576517
-
Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
-
Hanahan D, Folkman J: Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 1996, 86: 53-364.
-
(1996)
Cell
, vol.86
, pp. 353-364
-
-
Hanahan, D.1
Folkman, J.2
-
21
-
-
0033580889
-
Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF
-
Holash J, Maisonpierre PC, Compton D, Boland P, Alexander CR, Zagzag D, Yancopoulos GD, Wiegand SJ: Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF. Science 1999, 284:1994-1998.
-
(1999)
Science
, vol.284
, pp. 1994-1998
-
-
Holash, J.1
Maisonpierre, P.C.2
Compton, D.3
Boland, P.4
Alexander, C.R.5
Zagzag, D.6
Yancopoulos, G.D.7
Wiegand, S.J.8
-
22
-
-
0034648793
-
Vascular-specific growth factors and blood vessel formation
-
Yancopoulos GD, Davis S, Gale NW, Rudge JS, Wiegand SJ, Holash J: Vascular-specific growth factors and blood vessel formation. Nature 2000, 407:242-248.
-
(2000)
Nature
, vol.407
, pp. 242-248
-
-
Yancopoulos, G.D.1
Davis, S.2
Gale, N.W.3
Rudge, J.S.4
Wiegand, S.J.5
Holash, J.6
-
23
-
-
0035160312
-
Impaired recruitment of bone marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth
-
Lyden D, Hattori K, Dias S, Costa C, Blaikie P, Butros L, Chadburn A, Heissig B, Marks W, Witte L, Wu Y, Hicklin D, Zhu Z, Hackett NR, Crystal RG, Moore MAS, Hajjar KA, Manova K, Benezra R, Rafii S: Impaired recruitment of bone marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth. Nature Med 2001, 7:1194-1201.
-
(2001)
Nature Med.
, vol.7
, pp. 1194-1201
-
-
Lyden, D.1
Hattori, K.2
Dias, S.3
Costa, C.4
Blaikie, P.5
Butros, L.6
Chadburn, A.7
Heissig, B.8
Marks, W.9
Witte, L.10
Wu, Y.11
Hicklin, D.12
Zhu, Z.13
Hackett, N.R.14
Crystal, R.G.15
Moore, M.A.S.16
Hajjar, K.A.17
Manova, K.18
Benezra, R.19
Rafii, S.20
more..
-
24
-
-
0035001278
-
Activation of expression of hedgehog target genes in basal cell carcinomas
-
Bonifas JM, Pennypacker S, Chuang PT, McMahon AP, Williams M, Rosenthal A, De Sauvage FJ, Epstein EH: Activation of expression of hedgehog target genes in basal cell carcinomas. J Invest Dermatol 2001, 116:739-742.
-
(2001)
J. Invest. Dermatol.
, vol.116
, pp. 739-742
-
-
Bonifas, J.M.1
Pennypacker, S.2
Chuang, P.T.3
McMahon, A.P.4
Williams, M.5
Rosenthal, A.6
De Sauvage, F.J.7
Epstein, E.H.8
-
25
-
-
0030844141
-
Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours
-
Dahmane N, Lee J, Robins P, Heller P, Ruiz i Altaba A: Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours. Nature 1997, 389: 76-881.
-
(1997)
Nature
, vol.389
, pp. 876-881
-
-
Dahmane, N.1
Lee, J.2
Robins, P.3
Heller, P.4
Ruiz i Altaba, A.5
-
26
-
-
0035691884
-
The sonic hedgehog-Gli pathway regulates dorsal brain growth and tumorigenesis
-
Dahmane N, Sanchez P, Gitton Y, Palma V, Sun T, Beyna M, Weiner H, Ruiz i Altaba A: The sonic hedgehog-Gli pathway regulates dorsal brain growth and tumorigenesis. Development 2001, 128: 201-5212.
-
(2001)
Development
, vol.128
, pp. 5201-5212
-
-
Dahmane, N.1
Sanchez, P.2
Gitton, Y.3
Palma, V.4
Sun, T.5
Beyna, M.6
Weiner, H.7
Ruiz i Altaba, A.8
-
27
-
-
0036181660
-
Expression of a sonic hedgehog signal transducer, hedgehog-interacting protein, by human basal cell carcinoma
-
Tojo M, Kiyosawa H, Iwatsuki K, Kaneko F: Expression of a sonic hedgehog signal transducer, hedgehog-interacting protein, by human basal cell carcinoma. Brit J Dermatol 2002, 146:69-73.
-
(2002)
Brit. J. Dermatol.
, vol.146
, pp. 69-73
-
-
Tojo, M.1
Kiyosawa, H.2
Iwatsuki, K.3
Kaneko, F.4
-
28
-
-
1642347847
-
Immunoprevention of Basal Cell Carcinomas with Recombinant Hedgehog-interacting Protein
-
Vogt A, Chuang P-T, Hebert J, Hwang J, Lu Y, Kopelovich L, Athar M, Bickers DR, Epstein EH Jr: Immunoprevention of Basal Cell Carcinomas with Recombinant Hedgehog-interacting Protein. J Exp Med 2004, 199:753-761.
-
(2004)
J. Exp. Med.
, vol.199
, pp. 753-761
-
-
Vogt, A.1
Chuang, P.-T.2
Hebert, J.3
Hwang, J.4
Lu, Y.5
Kopelovich, L.6
Athar, M.7
Bickers, D.R.8
Epstein Jr., E.H.9
-
29
-
-
0037374199
-
Evidence for lack of enhanced hedgehog target gene expression in common extracutaneous tumors
-
Hu Z, Bonifas JM, Aragon G, Kopelovich L, Liang Y, Ohta S, Israel M, Bickers DR, Aszterbaum M, Epstein EH: Evidence for lack of enhanced hedgehog target gene expression in common extracutaneous tumors. Cancer Res 2003, 63:923-928.
-
(2003)
Cancer Res.
, vol.63
, pp. 923-928
-
-
Hu, Z.1
Bonifas, J.M.2
Aragon, G.3
Kopelovich, L.4
Liang, Y.5
Ohta, S.6
Israel, M.7
Bickers, D.R.8
Aszterbaum, M.9
Epstein, E.H.10
-
30
-
-
0035819518
-
Angiogenic potential of prostate carcinoma cells overexpressing bcl-2
-
Fernandez A, Udagawa T, Schwesinger C, Beecken WD, Achilles-Gerte E, McDonnell TJ, D'Amato RJ: Angiogenic potential of prostate carcinoma cells overexpressing bcl-2. J Natl Cancer I 2001, 93:208-212.
-
(2001)
J. Natl. Cancer I
, vol.93
, pp. 208-212
-
-
Fernandez, A.1
Udagawa, T.2
Schwesinger, C.3
Beecken, W.D.4
Achilles-Gerte, E.5
McDonnell, T.J.6
D'Amato, R.J.7
-
31
-
-
0036571304
-
Growth inhibition of prostate cancer xenografts by halofuginone
-
Gavish Z, Pinthus JH, Barak V, Ramon J, Nagler A, Eshhar Z, Pines M: Growth inhibition of prostate cancer xenografts by halofuginone. The Prostate 2002, 51:73-83.
-
(2002)
The Prostate
, vol.51
, pp. 73-83
-
-
Gavish, Z.1
Pinthus, J.H.2
Barak, V.3
Ramon, J.4
Nagler, A.5
Eshhar, Z.6
Pines, M.7
-
32
-
-
0034648765
-
Angiogenesis in cancer and other diseases
-
Carmeliet P, Jain RK: Angiogenesis in cancer and other diseases. Nature 2000, 407:246-257.
-
(2000)
Nature
, vol.407
, pp. 246-257
-
-
Carmeliet, P.1
Jain, R.K.2
-
33
-
-
0038347409
-
The therapeutic potential of novel antiangiogenic therapies
-
Scappaticci FA: The therapeutic potential of novel antiangiogenic therapies. Expert Opin Inv Drugs 2003, 12: 23-932.
-
(2003)
Expert Opin. Inv. Drugs
, vol.12
, pp. 923-932
-
-
Scappaticci, F.A.1
|