Small-molecule synthetic compound norcantharidin reverses multi-drug resistance by regulating Sonic hedgehog signaling in human breast cancer cells.

PloS one

Volumn 7, Issue 5, 2012, Pages

  Chen, Yu Jen ^a   Kuo, Cheng Deng ^b   Chen, Szu Han ^b   Chen, Wei Jen ^b   Huang, Wen Chien ^b   Chao, K S Clifford ^b   Liao, Hui Fen ^b  

^a MACKAY MEMORIAL HOSPITAL   (Taiwan)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC ANTIBIOTIC; CARRIER PROTEIN; DOXORUBICIN; DRUG DERIVATIVE; FUSED HETEROCYCLIC RINGS; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN; NAVELBINE; NORCANTHARIDIN; SHH PROTEIN, HUMAN; SONIC HEDGEHOG PROTEIN; VINBLASTINE;

ARTICLE; BREAST TUMOR; CELL STRAIN MCF 7; CELL SURVIVAL; DRUG EFFECT; DRUG RESISTANCE; FEMALE; GENETICS; HUMAN; METABOLISM; MULTIDRUG RESISTANCE; PATHOLOGY; SIGNAL TRANSDUCTION; UPREGULATION;

ANTIBIOTICS, ANTINEOPLASTIC; BICYCLO COMPOUNDS, HETEROCYCLIC; BREAST NEOPLASMS; CARRIER PROTEINS; CELL SURVIVAL; DOXORUBICIN; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; FEMALE; HEDGEHOG PROTEINS; HUMANS; MCF-7 CELLS; P-GLYCOPROTEIN; RNA, MESSENGER; SIGNAL TRANSDUCTION; UP-REGULATION; VINBLASTINE;

EID: 84870840267     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0037006     Document Type: Article

References (0)