Purkinje-cell-derived Sonic hedgehog regulates granule neuron precursor cell proliferation in the developing mouse cerebellum

Current Biology

Volumn 9, Issue 8, 1999, Pages 445-448

  Wallace, Valerie A ^a  

^a OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BROXURIDINE; CELL PROLIFERATION; MOUSE; SONIC HEDGEHOG PROTEIN;

ERINACEIDAE; MAMMALIA;

EID: 0033594537     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(99)80195-X     Document Type: Article

References (23)

1. 1. Miale I, Sidman RL: An autoradiographic analysis of histogenesis in the mouse cerebellum. Exp Neurol 1961, 4:277-296.
2. 2. Wetts R, Herrup K: Direct correlation between Purkinje and granule cell number in the cerebella of lurcher chimeras and wild-type mice. Brain Res 1983, 312:41-47.
3. 3. Herrup K, Sunter K: Numerical matching during cerebellar development: quantitative analysis of granule cell death in staggerer mouse chimeras. J Neurosci 1987, 7:829-836.
4. 4. Smeyne RJ, Chu T, Lewin A, Bian F, S-Crisman S, Kunsch C, et al.: Local control of granule cell generation by cerebellar Purkinje cells. Mol Cell Neurosci 1995, 6:230-251.
5. 5. Goodrich LV, Scott MP: Hedgehog and patched in neural development and disease. Neuron 1998, 21:1243-1257.
6. 6. Ericson J, Morton S, Kawakami A, Roelink H, Jessell TM: Two critical periods of Sonic Hedgehog signaling required for the specification of motor neuron identity. Cell 1996, 87:661-673.
7. 7. Hammerschmidt M, Brook A, McMahon AP: The world according to hedgehog. Trends Genet 1997, 13:14-21.
8. 8. Ruiz i Altaba A: Catching a Gli-mpse of Hedgehog. Cell 1997, 90:193-196.
9. 9. Echelard Y, Epstein DJ, St-Jacques B, Shen L, Mohler J, McMahon JA, et al.: Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity. Cell 1993, 75:1417-1430.
10. 10. Traiffort E, Charytoniuk DA, Faure H, Ruat M: Regional distribution of Sonic Hedgehog, patched, and smoothened mRNA in the adult rat brain. J Neurochem 1998, 70:1327-1330.
11. 11. Mason CW, Williams AF: The kinetics of antibody binding to membrane antigens in solution at the cell surface. Biochem J 1980, 187:1-20.
12. 12. Altman J, Anderson WJ, Wright KA: Early effects of x-irradiation of the cerebellum in infant rats: decimation and reconstitution of the external granular layer. Exp Neurol 1969, 24:196-216.
13. 13. Porter JA, Ekker SC, Park WJ, Von Kessler DP, Young KE, Chen CH, et al.: Hedgehog patterning activity: role of a lipophilic modification mediated by the carboxy-terminal autoprocessing domain. Cell 1996, 86:21-34.
14. 14. Porter JA, Young KE, Beachy PA: Cholesterol modification of hedgehog signaling proteins in animal development. Science 1996, 274:255-259.
15. 15. Pepinsky RB, Zeng C, Wen D, Rayhorn P, Baker DP, Williams KP, et al.: Identification of a palmitic acid-modified form of human Sonic hedgehog. J Biol Chem 1998, 273:14037-14045.
16. 16. Wechsler-Reya RJS, Scott MP: Control of neuronal precursor proliferation in the cerebellum by Sonic hedgehog. Neuron 1999, 22:103-114.
17. 17. Tao Y, Black IB, DiCicco-Bloom E: Neurogenesis in neonatal rat brain is regulated by peripheral injection of basic fibroblast growth factor (bFGF). J Comp Neurol 1996, 376:653-663.
18. 18. Tao Y, Black IB, DiCicco-Bloom E: In vivo neurogenesis is inhibited by neutralizing antibodies to basic fibroblast growth factor. J Neurobiol 1997, 33:289-296.
19. 19. Gao WO, Heintz N, Hatten ME: Cerebellar granule cell neurogenesis is regulated by cell-cell interactions in vitro. Neuron 1991, 6:705-715.
20. 20. Alcedo J, Ayzenzon M, Von Ohlen T, Noll M, Hooper JE: The Drosophila smoothened gene encodes a seven-pass membrane protein, a putative receptor for the hedgehog signal. Cell 1996, 86: 221-232.
21. 21. van den Heuvel M, Ingham OW: Smoothened encodes a receptor-like serpentine protein required for hedgehog signalling. Nature 1996, 382: 547-551.
22. 22. Jensen AM, Wallace VA: Expression of Sonic hedgehog and its putative role as a precursor cell mitogen in the developing mouse retina. Development 1997, 124:363-371.
23. 23. Sidman LR: Histogenesis of mouse retina studied with thymidine-H3. In The Structure of the Eye. Edited by Smelser KG. New York: Academic Press; 1961 :487-506.