Feedback control of mammalian Hedgehog signaling by the Hedgehog-binding protein, Hip1, modulates Fgf signaling during branching morphogenesis of the lung

Genes and Development

Volumn 17, Issue 3, 2003, Pages 342-347

  Chuang, Pao Tien ^a   Kawcak, T'Nay ^a   McMahon, Andrew P ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b HARVARD UNIVERSITY   (United States)

Author keywords

Branching morphogenesis; Feedback regulation; Fgf10; Hedgehog; Hip1; Lung

Indexed keywords

FIBROBLAST GROWTH FACTOR; HEDGEHOG BINDING PROTEIN; PROTEIN HIP1; PROTEIN PATCHED 1; RECEPTOR PROTEIN; SONIC HEDGEHOG PROTEIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRANCHING MORPHOGENESIS; CELL SIZE; EMBRYO; EMBRYO DEVELOPMENT; ENCHONDRAL OSSIFICATION; FEEDBACK SYSTEM; LUNG DEVELOPMENT; MOUSE; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

ANIMALS; CARRIER PROTEINS; FEEDBACK; FIBROBLAST GROWTH FACTORS; HEDGEHOG PROTEINS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LUNG; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; MICE; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS; UP-REGULATION;

ANIMALIA; ERINACEIDAE; INVERTEBRATA; MAMMALIA; VERTEBRATA;

EID: 0037314331     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.1026303     Document Type: Article

References (19)

1. Bellusci, S., Grindley, J., Emoto, H., Itoh, N., and Hogan, B.L. 1997. Fibroblast growth factor 10 (FGF10) and branching morphogenesis in the embryonic mouse lung. Development 124: 4867-4878.
2. Chuang, P.-T. and McMahon, A.P. 1999. Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein. Nature 397: 617-621.
3. Goodrich, L.V., Johnson, R.V., Milenkovic, L., McMahon, J.A., and Scott, M.P. 1996. Conservation of the hedgehog/patched signaling pathway from flies to mice: Induction of a mouse patched gene by Hedgehog. Genes & Dev. 10: 301-312.
4. Hogan, B.L. 1999. Morphogenesis. Cell 96: 225-233.
5. Hogan, B., Beddington, R., Costantini, F., and Lacy, E. 1994. Manipulating the mouse embryo: A laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
6. Ingham, P.W. and McMahon, A.P. 2001. Hedgehog signaling in animal development: paradigms and principles. Genes & Dev. 15: 3059-3087.
7. Ishibashi, M. and McMahon, A.P. 2002. A Sonic hedgehog-dependent signaling relay regulates growth of diencephalic and mesencephalic primordial in the early mouse embryo. Development 129: 4807-4819.
8. Laufer, E., Nelson, C.E., Johnson, R.L., Morgan, B.A., and Tabin, C. 1994. Sonic hedgehog and Fgf-4 act through a signaling cascade and feedback loop to integrate growth and patterning of the developing limb bud. Cell 79: 993-1003.
9. Litingtung, Y., Lei, L., Westphal, H., and Chiang, C. 1998. Sonic hedgehog is essential to foregut development. Nat. Genet. 20: 58-61.
10. McMahon, A.P., Ingham, P.W., and Tabin, C.J. 2003. The developmental roles and clinical significance of Hedgehog signaling. Curr. Top. Dev. Biol. (In press).
11. Milenkovic, L., Goodrich, L.V., Higgins, K.M., and Scott, M.P. 1999. Mouse patchedl controls body size determination and limb patterning. Development 126: 4431-4440.
12. Min, H., Danilenko, D.M., Scully, S.A., Bolon, B., Ring, B.D., Tarpley, J.E., DeRose, M., and Simonet, W.S. 1998. Fgf-10 is required for both limb and lung development and exhibits striking functional similarity to Drosophila branchless. Genes & Dev. 12: 3156-3161.
13. Niswander, L., Jeffrey, S., Martin, G.R., and Tickle, C. 1994. A positive feedback loop coordinates growth and patterning in the vertebrate limb. Nature 371: 609-612.
14. Park, W.Y., Miranda, B., Lebeche, D., Hashimoto, G., and Cardoso, W.V. 1998. FGF-10 is a chemotactic factor for distal epithelial buds during lung development. Dev. Biol. 201: 125-134.
15. Pepicelli, C.V., Lewis, P.M., and McMahon, A.P. 1998. Sonic hedgehog regulates branching morphogenesis in the mammalian lung. Curr. Biol. 8: 1083-1086.
16. Sambrook, J. and Russell, D.W. 2001. Molecular cloning: A laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
17. Sekine, K., Ohuchi, H., Fujiwara, M., Yamasaki, M., Yoshizawa, T., Sato, T., Yagishita, N., Matsui, D., Koga, Y., Itoh, N., et al. 1999. Fgf10 is essential for limb and lung formation. Nat. Genet. 21: 138-141.
18. Warburton, D., Schwarz, M., Tefft, D., Flores-Delgado, G., Anderson, K.D., and Cardoso, W.V. 2000. The molecular basis of lung morphogenesis. Mech. Dev. 92: 55-81.
19. Wilkinson, D.G. and Nieto, M.A. 1993. Detection of messenger RNA by in situ hybridization to tissue sections and whole mounts. Methods Enzymol. 225: 361-373.