New insights into p53 signaling and cancer cell response to DNA damage: Implications for cancer therapy

Journal of Biomedicine and Biotechnology

Volumn 2012, Issue , 2012, Pages

  Mirzayans, Razmik ^a   Andrais, Bonnie ^a   Scott, April ^a   Murray, David ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS SIGNAL REGULATING KINASE 1; ARF PROTEIN; ATM PROTEIN; CASPASE 3; CYCLIN B1; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLINE; DNA; EPIDERMAL GROWTH FACTOR RECEPTOR; ETOPOSIDE; EVEROLIMUS; MITOGEN ACTIVATED PROTEIN KINASE; MULTIDRUG RESISTANCE PROTEIN 1; MYC PROTEIN; PACLITAXEL; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BCL 2; PROTEIN KINASE B; PROTEIN MCL 1; PROTEIN MDM2; PROTEIN P21; PROTEIN P53; RETINOBLASTOMA PROTEIN; ROSCOVITINE; SMALL INTERFERING RNA; SURVIVIN; TRICHOSTATIN A; UNINDEXED DRUG; VINBLASTINE; CYCLIN DEPENDENT KINASE INHIBITOR 1A;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; CANCER CELL; CANCER CELL CULTURE; CANCER THERAPY; CELL AGING; CELL CYCLE CHECKPOINT; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE PHASE; CELL CYCLE PROGRESSION; CELL DEATH; CELL PROLIFERATION; CELL SURVIVAL; CELLULAR DISTRIBUTION; CPG ISLAND; DNA DAMAGE; DNA REPAIR; FIBROBLAST; GAIN OF FUNCTION MUTATION; GENE EXPRESSION; GENE REPRESSION; HUMAN; IMMUNOFLUORESCENCE MICROSCOPY; IN VITRO STUDY; IN VIVO STUDY; LOSS OF FUNCTION MUTATION; MEDIATOR; MISSENSE MUTATION; MITOSIS; MOLECULAR DYNAMICS; ONCOGENE C MYC; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; RADIATION EXPOSURE; RECEPTOR DOWN REGULATION; REVIEW; SIGNAL TRANSDUCTION; TUMOR CELL LINE; TUMOR SUPPRESSOR GENE; WESTERN BLOTTING; WILD TYPE; ANIMAL; CHEMISTRY; GENETICS; METABOLISM; MUTATION; NEOPLASM; PATHOLOGY;

ANIMALS; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DNA DAMAGE; HUMANS; MUTATION; NEOPLASMS; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84864926277     PISSN: 11107243     EISSN: 11107251     Source Type: Journal    
DOI: 10.1155/2012/170325     Document Type: Review

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