Tumor-derived p53 mutant c174y is a gain-of-function mutant which activates the fos promoter and enhances colony formation

International Journal of Cancer

Volumn 88, Issue 2, 2000, Pages 162-171

  Preuss, Ute ^a   Kreutzfeld, Rene ^a   Scheidtmann, Karl Heinz ^a  

^a UNIVERSITY OF BONN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLINE; PROTEIN BAX; PROTEIN MDM2; PROTEIN P53; VIRUS LARGE T ANTIGEN;

AMINO ACID SUBSTITUTION; ANTIGEN EXPRESSION; ARTICLE; CANCER GROWTH; CARCINOGENESIS; DNA BINDING; GENE INACTIVATION; HUMAN; HUMAN CELL; MALIGNANT TRANSFORMATION; NEUROECTODERM TUMOR; ONCOGENE C FOS; PRIORITY JOURNAL; PROMOTER REGION; SITE DIRECTED MUTAGENESIS; TRANSACTIVATION; TRANSCRIPTION REGULATION; VIRUS INHIBITION;

AMINO ACID SUBSTITUTION; ANIMAL; ANTIGENS, POLYOMAVIRUS TRANSFORMING; BRAIN NEOPLASMS; COLONY-FORMING UNITS ASSAY; CYSTEINE; GENES, FOS; GENES, P53; GENES, REPORTER; HUMAN; MUTAGENESIS, SITE-DIRECTED; OSTEOSARCOMA; POINT MUTATION; PROMOTER REGIONS (GENETICS); PROTEIN P53; RATS; RECOMBINANT PROTEINS; SUPPORT, NON-U.S. GOV'T; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION, GENETIC; TRANSFECTION; TUMOR CELLS, CULTURED; TYROSINE;

EID: 0033813790     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-0215(20001015)88:2<162::AID-IJC3>3.0.CO;2-M     Document Type: Article

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