Growth inhibition by CDK-cyclin and PCNA binding domains of p21 occurs by distinct mechanisms and is regulated by ubiquitin-proteasome pathway

Oncogene

Volumn 18, Issue 21, 1999, Pages 3290-3302

  Rousseau, Denis ^a   Cannella, Dominique ^a   Boulaire, Jerome ^a   Fitzgerald, Patrick ^b   Fotedar, Arun ^b   Fotedar, Rati ^a  

^a INSTITUT DE BIOLOGIE STRUCTURALE   (France)

^b SIDNEY KIMMEL CANCER CENTER   (United States)

Author keywords

CDK; Cell cycle; p21(WAF1 Cip1); PCNA; Proteasome; Ubiquitination

Indexed keywords

CYCLINE; ELONGATION FACTOR 2; PROTEASOME; PROTEIN P21; UBIQUITIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; DNA SYNTHESIS INHIBITION; GROWTH INHIBITION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL;

3T3 CELLS; ANIMALS; BINDING SITES; CARRIER PROTEINS; CDC2-CDC28 KINASES; CELL CYCLE PROTEINS; CELL DIVISION; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASES; CYCLINS; CYSTEINE ENDOPEPTIDASES; DNA-BINDING PROTEINS; E2F TRANSCRIPTION FACTORS; GENETIC VECTORS; HUMANS; MICE; MULTIENZYME COMPLEXES; MUTAGENESIS; PROLIFERATING CELL NUCLEAR ANTIGEN; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN-SERINE-THREONINE KINASES; RECOMBINANT FUSION PROTEINS; S PHASE; TRANSCRIPTION FACTOR DP1; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED; UBIQUITINS;

EID: 0033609369     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1202681     Document Type: Article

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