Two-phase dynamics of p53 in the DNA damage response

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 22, 2011, Pages 8990-8995

  Zhang, Xiao Peng ^a   Liu, Feng ^a   Wang, Wei ^a  

^a NANJING UNIVERSITY   (China)

Author keywords

Bistability; Digital mode; Numerical simulations; Signal transduction

Indexed keywords

ATM PROTEIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; PROTEIN MDM2; PROTEIN P53; SERINE; UNCLASSIFIED DRUG; WIP1 PROTEIN;

APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL DAMAGE; CELL FATE; CELL FUNCTION; CONTROLLED STUDY; DNA DAMAGE; DNA MODIFICATION; DNA REPAIR; GENE ACTIVATION; GENE SWITCHING; HUMAN; HUMAN CELL; IONIZING RADIATION; NEGATIVE FEEDBACK; PHASE TRANSITION; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; SIGNAL TRANSDUCTION; SIMULATION;

APOPTOSIS; CELL CYCLE PROTEINS; CELL LINEAGE; DNA DAMAGE; DNA REPAIR; DNA-BINDING PROTEINS; GENES, P53; HUMANS; MODELS, THEORETICAL; NEOPLASMS; OSCILLOMETRY; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; SERINE; SIGNAL TRANSDUCTION; TIME FACTORS; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

ATAXIA TELANGIECTASIA;

EID: 79959343390     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1100600108     Document Type: Article

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