p21/CDKN1A mediates negative regulation of transcription by p53

Journal of Biological Chemistry

Volumn 278, Issue 35, 2003, Pages 32507-32516

  Löhr, Kristina ^a   Möritz, Constanze ^a   Contente, Ana ^a   Dobbelstein, Matthias ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ENERGY; CELLS; DNA; GENETIC ENGINEERING;

TRANSCRIPTION;

TUMORS;

CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE 1; DNA; GENE PRODUCT; MYC PROTEIN; PROTEIN P21; PROTEIN P53; PROTEIN P73; STATHMIN; SURVIVIN;

AMINO TERMINAL SEQUENCE; APOPTOSIS; ARTICLE; BINDING SITE; CELL DEATH; CONTROLLED STUDY; DOWN REGULATION; GENE ACTIVATION; GENE CONTROL; GENE DELETION; GENE EXPRESSION; GENE INTERACTION; GENE MUTATION; GENE OVEREXPRESSION; GENE REPRESSION; GENE TARGETING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN DOMAIN; TRANSACTIVATION; TUMOR SUPPRESSOR GENE;

ADENOVIRIDAE; AMINO ACID SEQUENCE; APOPTOSIS; BASE SEQUENCE; BINDING SITES; CELL LINE; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; DNA-BINDING PROTEINS; GENE DELETION; GENE EXPRESSION REGULATION; GENES, P53; GENES, TUMOR SUPPRESSOR; GENETIC VECTORS; HUMANS; IMMUNOBLOTTING; MICROTUBULE PROTEINS; MICROTUBULE-ASSOCIATED PROTEINS; MITOCHONDRIA; MOLECULAR SEQUENCE DATA; MUTATION; NEOPLASM PROTEINS; NUCLEAR PROTEINS; PHOSPHOPROTEINS; PLASMIDS; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS C-MYC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STATHMIN; TIME FACTORS; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION, GENETIC; TRANSFECTION; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 0041857759     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M212517200     Document Type: Article

References (75)

1. Vousden, K. H. (2000) Cell 103, 691-694
2. Vousden, K. H., and Lu, X. (2002) Nat. Rev. Cancer 2, 594-604
3. Vogelstein, B., Lane, D., and Levine, A. J. (2000) Nature 408, 307-310
4. Sabbatini, P., Chiou, S. K., Rao, L., and White, E. (1995) Mol. Cell Biol. 15, 1060-1070
5. Shen, Y., and Shenk, T. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 8940-8944
6. Maheswaran, S., Englert, C., Bennett, P., Heinrich, G., and Haber, D. A. (1995) Genes Dev. 9, 2143-2156
7. Murphy, M., Hinman, A., and Levine, A. J. (1996) Genes Dev. 10, 2971-2980
8. Roth, J., Koch, P., Contente, A., and Dobbelstein, M. (2000) Oncogene 19, 1834-1842
9. Venot, C., Maratrat, M., Dureuil, C., Conseiller, E., Bracco, L., and Debussche, L. (1998) EMBO J. 17, 4668-4679
10. Ryan, K. M., and Vousden, K. H. (1998) Mol. Cell Biol. 18, 3692-3698
11. Murphy, M., Ahn, J., Walker, K. K., Hoffman, W. H., Evans, R. M., Levine, A. J., and George, D. L. (1999) Genes Dev. 13, 2490-2501
12. Hoffman, W. H., Biade, S., Zilfou, J. T., Chen, J., and Murphy, M. (2002) J. Biol. Chem. 277, 3247-3257
13. Lin, J., Chen, J., Elenbaas, B., and Levine, A. J. (1994) Genes Dev. 8, 1235-1246
14. Zilfou, J. T., Hoffman, W. H., Sank, M., George, D. L., and Murphy, M. (2001) Mol. Cell Biol. 21, 3974-3985
15. el-Deiry, W. S., Tokino, T., Velculeseu, V. E., Levy, D. B., Parsons, R., Trent, J. M., Lin, D., Mercer, W. E., Kinzler, K. W., and Vogelstein, B. (1993) Cell 75, 817-825
16. Bartek, J., and Lukas, J. (2001) FEBS Lett. 490, 117-122
17. Gottifredi, V., Karni-Schmidt, O., Shieh, S. S., and Prives, C. (2001) Mol. Cell Biol. 21, 1066-1076
18. Taylor, W. R., Schonthal, A. H., Galante, J., and Stark, G. R. (2001) J. Biol. Chem. 276, 1998-2006
19. Flatt, P. M., Tang, L. J., Scatena, C. D., Szak, S. T., and Pietenpol, J. A. (2000) Mol. Cell Biol. 20, 4210-4223
20. Bunz, F., Dutriaux, A., Lengauer, C., Waldman, T., Zhou, S., Brown, J. P., Sedivy, J. M., Kinzler, K. W., and Vogelstein, B. (1998) Science 282, 1497-1501
21. Li, F., and Altieri, D. C. (1999) Biochem. J. 344, 305-311
22. Koch, P., Gatfield, J., Löber, C., Hobom, U., Lenz-Stöppler, C., Roth, J., and Dobbelstein, M. (2001) Cancer Res. 61, 5941-5947
23. Kartasheva, N. N., Contente, A., Lenz-Stoppler, C., Roth, J., and Dobbelstein, M. (2002) Oncogene 21, 4715-4727
24. Menssen, A., and Hermeking, H. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 6274-6279
25. Yang, Z. Y., Perkins, N. D., Ohno, T., Nabel, E. G., and Nabel, G. J. (1995) Nat. Med. 1, 1052-1056
26. He, T. C., Zhou, S., da Costa, L. T., Yu, J., Kinzler, K. W., and Vogelstein, B. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 2509-2514
27. Kaghad, M., Bonnet, H., Yang, A., Creancier, L., Biscan, J. C., Valent, A., Minty, A., Chalon, P., Lelias, J. M., Dumont, X., Ferrara, P., McKeon, F., and Caput, D. (1997) Cell 90, 809-819
28. Weigel, S., and Dobbelstein, M. (2000) J. Virol. 74, 764-772
29. Contente, A., Dittmer, A., Koch, M. C., Roth, J., and Dobbelstein, M. (2002) Nat. Genet. 80, 315-320
30. Cuconati, A., Degenhardt, K., Sundararajan, R., Anschel, A., and White, E. (2002) J. Virol. 76, 4547-4558
31. Debbas, M., and White, E. (1993) Genes Dev. 7, 546-554
32. Lazebnik, Y. A., Kaufmann, S. H., Desnoyers, S., Poirier, G. G., and Earnshaw, W. C. (1994) Nature 371, 346-347
33. Troy, C. M., Stefanis, L., Prochiantz, A., Greene, L. A., and Shelanski, M. L. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 5635-5640
34. el-Deiry, W. S., Kern, S. E., Pietenpol, J. A., Kinzler, K. W., and Vogelstein, B. (1992) Nat. Genet. 1, 45-49
35. Zauberman, A., Barak, Y., Ragimov, N., Levy, N., and Oren, M. (1993) EMBO J. 12, 2799-2808
36. Hupp, T. R., Meek, D. W., Midgley, C. A., and Lane, D. P. (1992) Cell 71, 875-886
37. Polyak, K., Xia, Y., Zweier, J. L., Kinzler, K. W., and Vogelstein, B. (1997) Nature 389, 300-305
38. Seoane, J., Le, H. V., and Massague, J. (2002) Nature 419, 729-734
39. Vousden, K. H. (2002) Cancer Cell 2, 351-352
40. Muller, H., and Helin, K. (2000) Biochim. Biophys. Acta 1470, M1-12
41. Wunderlich, M., and Berberich, S. J. (2002) Oncogene 21, 4414-4421
42. Polager, S., and Ginsberg, D. (2002) J. Biol. Chem. 21, 21
43. Lasorella, A., Noseda, M., Beyna, M., Yokota, Y., and Iavarone, A. (2000) Nature 407, 592-598
44. Zwicker, J., Lucibello, F. C., Wolfraim, L. A., Gross, C., Truss, M., Engeland, K., and Muller, R. (1995) EMBO J. 14, 4514-4522
45. Manni, I., Mazzaro, G., Gurtner, A., Mantovani, R., Haugwitz, U., Krause, K., Engeland, K., Sacchi, A., Soddu, S., and Piaggio, G. (2001) J. Biol. Chem. 276, 5570-5576
46. Yun, J., Chae, H. D., Choy, H. E., Chung, J., Yoo, H. S., Han, M. H., and Shin, D. Y. (1999) J. Biol. Chem. 274, 29677-29682
47. Irwin, M., Marin, M. C., Phillips, A. C., Seelan, R. S., Smith, D. I., Liu, W., Flores, E. R., Tsai, K. Y., Jacks, T., Vousden, K. H., and Kaelin, W. G., Jr. (2000) Nature 407, 645-648
48. Stiewe, T., and Putzer, B. M. (2000) Nat. Genet. 26, 464-469
49. Zaika, A., Irwin, M., Sansome, C., and Moll, U. M. (2001) J. Biol. Chem. 276, 11310-11316
50. Mirza, A., McGuirk, M., Hockenberry, T. N., Wu, Q., Ashar, H., Black, S., Wen, S. F., Wang, L., Kirschmeier, P., Bishop, W. R., Nielsen, L. L., Pickett, C. B., and Liu, S. (2002) Oncogene 21, 2613-2622
51. Chan, T. A., Hwang, P. M., Hermeking, H., Kinzler, K. W., and Vogelstein, B. (2000) Genes Dev. 14, 1584-1588
52. Ambrosini, G., Adida, C., and Altieri, D. C. (1997) Nat. Med. 3, 917-921
53. Giodini, A., Kallio, M. J., Wall, N. R., Gorbsky, G. J., Tognin, S., Marchisio, P. C., Symons, M., and Altieri, D. C. (2002) Cancer Res. 62, 2462-2467
54. Park, M., Chae, H. D., Yun, J., Jung, M., Kim, Y. S., Kim, S. H., Han, M. H., and Shin, D. Y. (2000) Cancer Res. 60, 542-545
55. Buckbinder, L., Talbott, R., Velasco-Miguel, S., Takenaka, I., Faha, B., Seizinger, B. R., and Kley, N. (1995) Nature 377, 646-649
56. Harris, C. C. (1996) Carcinogenesis 17, 1187-1198
57. Chao, C., Saito, S., Kang, J., Anderson, C. W., Appella, E., and Xu, Y. (2000) EMBO J. 19, 4967-4975
58. Jimenez, G. S., Nister, M., Stommel, J. M., Beeche, M., Barcarse, E. A., Zhang, X. Q., O'Gorman, S., and Wahl, G. M. (2000) Nat. Genet. 26, 37-43
59. Yang, A., and McKeon, F. (2000) Nat. Rev. Mol. Cell Biol. 1, 199-207
60. MacLachlan, T. K., Dash, B. C., Dicker, D. T., and El-Deiry, W. S. (2000) J. Biol. Chem. 275, 31869-31875
61. Arizti, P., Fang, L., Park, I., Yin, Y., Solomon, E., Ouchi, T., Aaronson, S. A., and Lee, S. W. (2000) Mol. Cell Biol. 20, 7450-7459
62. Ishida, S., Huang, E., Zuzan, H., Spang, R., Leone, G., West, M., and Nevins, J. R. (2001) Mol. Cell Biol. 21, 4684-4699
63. Markey, M. P., Angus, S. P., Strobeck, M. W., Williams, S. L., Gunawardena, R. W., Aronow, B. J., and Knudsen, E. S. (2002) Cancer Res. 62, 6587-6597
64. Ren, B., Cam, H., Takahashi, Y., Volkert, T., Terragni, J., Young, R. A., and Dynlacht, B. D. (2002) Genes Dev. 16, 245-256
65. Liu, N., Lucibello, F. C., Engeland, K., and Muller, R. (1998) Oncogene 16, 2957-2963
66. Krause, K., Haugwitz, U., Wasner, M., Wiedmann, M., Mossner, J., and Engeland, K. (2001) Biochem. Biophys. Res. Commun. 284, 743-750
67. Badie, C., Itzhaki, J. E., Sullivan, M. J., Carpenter, A. J., and Porter, A. C. (2000) Mol. Cell Biol. 20, 2358-2366
68. Weinmann, A. S., Yan, P. S., Oberley, M. J., Huang, T. H., and Farnham, P. J. (2002) Genes Dev. 16, 235-244
69. Damia, G., Sanchez, Y., Erba, E., and Broggini, M. (2001) J. Biol. Chem. 276, 10641-10645
70. Krause, K., Wasner, M., Reinhard, W., Haugwitz, U., Dohna, C. L., Mossner, J., and Engeland, K. (2000) Nucleic Acids Res. 28, 4410-4418
71. Innocente, S. A., Abrahamson, J. L., Cogswell, J. P., and Lee, J. M. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 2147-2152
72. Zhao, R., Gish, K., Murphy, M., Yin, Y., Notterman, D., Hoffman, W. H., Tom, E., Mack, D. H., and Levine, A. J. (2000) Genes Dev. 14, 981-993
73. Li, B., and Lee, M. Y. (2001) J. Biol. Chem. 276, 29729-29739
74. Johnsen, J. I., Aurelio, O. N., Kwaja, Z., Jorgensen, G. E., Pellegata, N. S., Plattner, R., Stanbridge, E. J., and Cajot, J. F. (2000) Int. J. Cancer 88, 685-691
75. Ahn, J., Murphy, M., Kratowicz, S., Wang, A., Levine, A. J., and George, D. L. (1999) Oncogene 18, 5954-5958