Pathways involved in Drosophila and human cancer development: The Notch, Hedgehog, Wingless, Runt, and Trithorax pathway

Annals of Hematology

Volumn 91, Issue 5, 2012, Pages 645-669

  Geissler, Klaus ^a   Zach, Otto ^b  

^a LUDWIG BOLTZMANN INSTITUTE FOR LUNG VASCULAR RESEARCH   (Austria)

^b ELISABETHINEN HOSPITAL   (Austria)

Author keywords

Hedgehog; MLL; Notch; Runt; Wnt Catenin

Indexed keywords

ANTINEOPLASTIC AGENT; BMS 833923; CELECOXIB; CORTICOSTEROID; CYCLOPAMINE; ERISMODEGIB; FLAVOPIRIDOL; GAMMA SECRETASE INHIBITOR; INDOMETACIN; LEQ 506; MK 0752; N (6,7 DIHYDRO 6 OXO 5H DIBENZ[B,D]AZEPIN 7 YL) 2,2 DIMETHYL N' (2,2,3,3,3 PENTAFLUOROPROPYL)PROPANEDIAMIDE; NILOTINIB; NOTCH RECEPTOR; NOTCH1 RECEPTOR; NOTCH2 RECEPTOR; NOTCH3 RECEPTOR; P 03084014; PANOBINOSTAT; RAPAMYCIN; SARIDEGIB; SONIC HEDGEHOG PROTEIN; TAK 441; TRANSCRIPTION FACTOR RUNX; UNCLASSIFIED DRUG; VISMODEGIB; WNT1 PROTEIN; ZEBULARINE; DNA BINDING PROTEIN; DROSOPHILA PROTEIN; MIXED LINEAGE LEUKEMIA PROTEIN; MLL PROTEIN, HUMAN; NONHISTONE PROTEIN; NUCLEAR PROTEIN; RUN PROTEIN, DROSOPHILA; TRANSCRIPTION FACTOR; TRITHORAX PROTEIN, DROSOPHILA; WG PROTEIN, DROSOPHILA;

ADENOMATOUS POLYP; ADVANCED CANCER; ADVANCED NONHEMATOLOGIC CANCER; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; BASAL CELL CARCINOMA; BRAIN TUMOR; BREAST CANCER; CARCINOGENESIS; CENTRAL NERVOUS SYSTEM TUMOR; CHONDROSARCOMA; DESMOID TUMOR; DROSOPHILA MELANOGASTER; DRUG INTERACTION; FAMILIAL COLON POLYPOSIS; GENE FREQUENCY; GENE LOCATION; GENE MUTATION; GENE OVEREXPRESSION; GENE TARGETING; GLIOBLASTOMA; HUMAN; KIDNEY CARCINOMA; LEUKEMIA; LUNG NON SMALL CELL CANCER; LYMPHOMA; MEDULLOBLASTOMA; MELANOMA; NEOPLASM; NEUROENDOCRINE TUMOR; NONHUMAN; ONCOGENE; OVARY CANCER; PANCREAS ADENOCARCINOMA; PANCREAS CANCER; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVIEW; RHABDOMYOSARCOMA; SOLID TUMOR; SOMATIC MUTATION; T CELL LEUKEMIA; THYROID CANCER; TUMOR GROWTH; UNSPECIFIED SIDE EFFECT; ANIMAL; DISEASE MODEL; DROSOPHILA; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; METABOLISM; MOLECULARLY TARGETED THERAPY; MOUSE; SIGNAL TRANSDUCTION;

ANIMALS; ANTINEOPLASTIC AGENTS; CHROMOSOMAL PROTEINS, NON-HISTONE; DISEASE MODELS, ANIMAL; DNA-BINDING PROTEINS; DROSOPHILA; DROSOPHILA PROTEINS; HEDGEHOG PROTEINS; HUMANS; MICE; MOLECULAR TARGETED THERAPY; MYELOID-LYMPHOID LEUKEMIA PROTEIN; NEOPLASMS; NUCLEAR PROTEINS; PROGNOSIS; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; WNT1 PROTEIN;

EID: 84861429843     PISSN: 09395555     EISSN: 14320584     Source Type: Journal    
DOI: 10.1007/s00277-012-1435-0     Document Type: Review

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