Structures of the dual bromodomains of the P-TEFb-activating protein Brd4 at atomic resolution

Journal of Biological Chemistry

Volumn 284, Issue 52, 2009, Pages 36547-36556

  Vollmuth, Friederike ^a   Blankenfeldt, Wulf ^a   Geyer, Matthias ^a  

^a MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ATOMIC RESOLUTION; BINDING LIGANDS; CHROMATIN STRUCTURE; COMPLEX FORMATIONS; CYCLIN T1; DIMER FORMATION; HETERODIMERS; HISTONE H3; INTERACTION NETWORKS; ISOTHERMAL TITRATION CALORIMETRY; LINKER SEQUENCE; MUTATIONAL ANALYSIS; N-TERMINALS; RECOGNITION SPECIFICITY; RNA POLYMERASE II; TERMINAL DOMAIN; TRANSCRIPTIONAL ACTIVATORS;

AMINO ACIDS; BINDING ENERGY; CHROMATOGRAPHIC ANALYSIS; COMPLEXATION; PROTEINS; RNA; SIZE EXCLUSION CHROMATOGRAPHY;

CRYSTAL ATOMIC STRUCTURE;

ASPARAGINE; CYCLIN T1; HISTONE H3; HISTONE H4; LYSINE; NUCLEAR PROTEIN; PROTEIN BRD1; PROTEIN BRD2; PROTEIN BRD4; PROTEIN P TEFB; TRANSCRIPTION ELONGATION FACTOR; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CHROMATOGRAPHY; CONTROLLED STUDY; CRYSTAL STRUCTURE; DIMERIZATION; ISOTHERMAL TITRATION CALORIMETRY; LIGAND BINDING; MOUSE; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; STRUCTURE ANALYSIS;

ANIMALS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; HISTONES; MICE; NUCLEAR PROTEINS; POSITIVE TRANSCRIPTIONAL ELONGATION FACTOR B; PROTEIN STRUCTURE, TERTIARY; RNA POLYMERASE II; TRANSCRIPTION FACTORS;

EID: 73649124584     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.033712     Document Type: Article

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