메뉴 건너뛰기




Volumn 4, Issue 12, 1999, Pages 685-696

Molecular basis of tissue-specific gene expression mediated by the Runt domain transcription factor PEBP2/CBF

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; CORE BINDING FACTOR; POLYOMAVIRUS ENHANCER BINDING PROTEIN 2; PROTEIN SUBUNIT; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ETS 1; UNCLASSIFIED DRUG;

EID: 0033400822     PISSN: 13569597     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2443.1999.00298.x     Document Type: Review
Times cited : (165)

References (77)
  • 1
    • 0031782323 scopus 로고    scopus 로고
    • The leukemic protein CBFb-SMMHC sequesters CBFa2 into cytoskeletal filaments and aggregates
    • Adja, N., Stacy, T., Speck, N.A. & Liu, P.P. (1998) The leukemic protein CBFb-SMMHC sequesters CBFa2 into cytoskeletal filaments and aggregates. Mol. Cell. Biol. 18, 7432-7443.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 7432-7443
    • Adja, N.1    Stacy, T.2    Speck, N.A.3    Liu, P.P.4
  • 2
    • 0032539656 scopus 로고    scopus 로고
    • Negative regulation of granulocytic differentiation in the myeloid precursor cell line 32Dcl3 by ear-2, a mammalian homolog of Drosophila seven-up, and a chimeric leukemogenic gene, AML1/ETO(MTG8)
    • Ahn, M.-Y., Huang, G., Bae, S.-C., et al. (1998) Negative regulation of granulocytic differentiation in the myeloid precursor cell line 32Dcl3 by ear-2, a mammalian homolog of Drosophila seven-up, and a chimeric leukemogenic gene, AML1/ETO(MTG8). Proc. Natl. Acad. Sci. USA 95, 1812-1817.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 1812-1817
    • Ahn, M.-Y.1    Huang, G.2    Bae, S.-C.3
  • 3
    • 0031013844 scopus 로고    scopus 로고
    • A simple screening for mutant DNA binding proteins: Application to murine transcription factor PEBP2α subunit, a founding member of the Runt domain protein family
    • Akamatsu, Y., Tsukumo, S., Kagoshima, H., Tsurushita, N. & Shigesada, K. (1997) A simple screening for mutant DNA binding proteins: application to murine transcription factor PEBP2α subunit, a founding member of the Runt domain protein family. Gene 185, 111-117.
    • (1997) Gene , vol.185 , pp. 111-117
    • Akamatsu, Y.1    Tsukumo, S.2    Kagoshima, H.3    Tsurushita, N.4    Shigesada, K.5
  • 4
    • 0027538626 scopus 로고
    • Isolation of PEBP2αB cDNA representing the mouse homolog of human acute myeloid leukemia gene, AML1
    • Bae, S.C., Yamaguchi-Iwai, Y., Ogawa, E., et al. (1993) Isolation of PEBP2αB cDNA representing the mouse homolog of human acute myeloid leukemia gene, AML1. Oncogene 8, 809-814.
    • (1993) Oncogene , vol.8 , pp. 809-814
    • Bae, S.C.1    Yamaguchi-Iwai, Y.2    Ogawa, E.3
  • 5
    • 0028181612 scopus 로고
    • PEBP2αB/ mouse AML1 consists of multiple isoforms that possess differential transactivation potentials
    • Bae, S.-C., Ogawa, E., Maruyama, M., et al. (1994) PEBP2αB/ mouse AML1 consists of multiple isoforms that possess differential transactivation potentials. Mol. Cell. Biol. 14, 3242-3252.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 3242-3252
    • Bae, S.-C.1    Ogawa, E.2    Maruyama, M.3
  • 6
    • 0029016934 scopus 로고
    • Cloning, mapping and expression of PEBP2αC, a third gene encoding the mammalian Runt domain
    • Bae, S.-C., Takahashi, E., Zhang, Y.W., et al. (1995) Cloning, mapping and expression of PEBP2αC, a third gene encoding the mammalian Runt domain. Gene 159, 245-248.
    • (1995) Gene , vol.159 , pp. 245-248
    • Bae, S.-C.1    Takahashi, E.2    Zhang, Y.W.3
  • 7
    • 0029953941 scopus 로고    scopus 로고
    • An AML-1 consensus sequence binds an osteoblastspecific complex and transcriptionally activates the osteocalcin gene
    • Banerjee, C., Hiebert, S.W., Stein, J.L., Lian, J.B. & Stein, G.S. (1996) An AML-1 consensus sequence binds an osteoblastspecific complex and transcriptionally activates the osteocalcin gene. Proc. Natl Acad. Sci. USA 93, 4968-4973.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 4968-4973
    • Banerjee, C.1    Hiebert, S.W.2    Stein, J.L.3    Lian, J.B.4    Stein, G.S.5
  • 8
    • 0032498230 scopus 로고    scopus 로고
    • The enhanceosome and transcriptional synergy
    • Carey, M. (1998) The enhanceosome and transcriptional synergy. Cell 92, 5-8.
    • (1998) Cell , vol.92 , pp. 5-8
    • Carey, M.1
  • 9
    • 0031806004 scopus 로고    scopus 로고
    • The capacity of PEBP2αB (AML1/Cbfa2) to stimulate polyomavirus DNA replication is related to its affinity for the nuclear matrix
    • Chen, L.-F., Ito, K., Murakami, Y. & Ito, Y. (1998) The capacity of PEBP2αB (AML1/Cbfa2) to stimulate polyomavirus DNA replication is related to its affinity for the nuclear matrix. Mol. Cell. Biol. 18, 4165-4176.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 4165-4176
    • Chen, L.-F.1    Ito, K.2    Murakami, Y.3    Ito, Y.4
  • 10
    • 20644434934 scopus 로고    scopus 로고
    • SpRunt-1, a new member of the runt domain family of transcription factor, is a positive regulator of the aboral ectoderm-specific CylllA gene in sea urchin embryos
    • Coffman, J.A., Kirchhamer, C.V., Harrington, M.G. & Davidson, E.H. (1996) SpRunt-1, a new member of the runt domain family of transcription factor, is a positive regulator of the aboral ectoderm-specific CylllA gene in sea urchin embryos. Dev. Biol. 174, 43-54.
    • (1996) Dev. Biol. , vol.174 , pp. 43-54
    • Coffman, J.A.1    Kirchhamer, C.V.2    Harrington, M.G.3    Davidson, E.H.4
  • 11
    • 0029999211 scopus 로고    scopus 로고
    • Patterning of cells in the Drosophila eye by Lozenge, which shares homologous domains with AML1
    • Daga, A., Korlovich, C.A., Dumstrei, K. & Banerjee, U. (1996) Patterning of cells in the Drosophila eye by Lozenge, which shares homologous domains with AML1. Genes Dev. 10, 1194-1205.
    • (1996) Genes Dev. , vol.10 , pp. 1194-1205
    • Daga, A.1    Korlovich, C.A.2    Dumstrei, K.3    Banerjee, U.4
  • 12
    • 0021172471 scopus 로고
    • Chromosomal localizarion of the human proto-oncogene c-ets
    • de Taisne, C., Gegonne, A., Stehelin, D, Bernheim, A. & Berger, R. (1984) Chromosomal localizarion of the human proto-oncogene c-ets. Nature 310, 581-583.
    • (1984) Nature , vol.310 , pp. 581-583
    • De Taisne, C.1    Gegonne, A.2    Stehelin, D.3    Bernheim, A.4    Berger, R.5
  • 13
    • 0019787255 scopus 로고
    • Diffuse intraembryonic hematopoiesis in normal and chimeric avian development
    • Dieterlen-Liévre, F. & Martin, C. (1981) Diffuse intraembryonic hematopoiesis in normal and chimeric avian development. Dev. Biol. 88, 180-191.
    • (1981) Dev. Biol. , vol.88 , pp. 180-191
    • Dieterlen-Liévre, F.1    Martin, C.2
  • 14
    • 0030678549 scopus 로고    scopus 로고
    • Osf/Cbfa1: A transcriptional activator of osteoblast differentiation
    • Ducy, P., Zhang, R., Geoffroy, V., Ridall, A.L. & Karsenty G. (1997) Osf/Cbfa1: a transcriptional activator of osteoblast differentiation. Cell 89, 747-754.
    • (1997) Cell , vol.89 , pp. 747-754
    • Ducy, P.1    Zhang, R.2    Geoffroy, V.3    Ridall, A.L.4    Karsenty, G.5
  • 15
    • 0025721854 scopus 로고
    • The Drosophila segmentation gene runt acts as a position-specific numerator element necessary for the uniform expression of the sex-determining gene Sex-lethal
    • Duffy, J.B. & Gergen, J.P. (1991) The Drosophila segmentation gene runt acts as a position-specific numerator element necessary for the uniform expression of the sex-determining gene Sex-lethal. Genes Dev. 5, 2176-2187.
    • (1991) Genes Dev. , vol.5 , pp. 2176-2187
    • Duffy, J.B.1    Gergen, J.P.2
  • 16
    • 0026321595 scopus 로고
    • Expression and function of the Drosophila gene runt in early stages of neural development
    • Duffy, J.B., Kania, M.A. & Gergen, J.P. (1991) Expression and function of the Drosophila gene runt in early stages of neural development. Development 113, 1223-1230.
    • (1991) Development , vol.113 , pp. 1223-1230
    • Duffy, J.B.1    Kania, M.A.2    Gergen, J.P.3
  • 17
    • 0028986250 scopus 로고
    • Assembly and function of a TCRα enhancer complex is dependent on LEF-1-induce DNA bending and multiple protein-protein interactions
    • Giese, K., Kingsley, C., Kirshner, J.R. & Crosschedl, R. (1995) Assembly and function of a TCRα enhancer complex is dependent on LEF-1-induce DNA bending and multiple protein-protein interactions. Genes Dev. 9, 995-1008.
    • (1995) Genes Dev. , vol.9 , pp. 995-1008
    • Giese, K.1    Kingsley, C.2    Kirshner, J.R.3    Crosschedl, R.4
  • 18
    • 0032985363 scopus 로고    scopus 로고
    • Molecular insights into PEBP2/CBFb-SMMHC associated acute leukemia revealed from the three-dimensional structure of PEBP2/ CBFb
    • Goger, M., Gupta, V., Kim, W.-Y., et al. (1999) Molecular insights into PEBP2/CBFb-SMMHC associated acute leukemia revealed from the three-dimensional structure of PEBP2/ CBFb. Nature Struct. Biol. 6, 620-623.
    • (1999) Nature Struct. Biol. , vol.6 , pp. 620-623
    • Goger, M.1    Gupta, V.2    Kim, W.-Y.3
  • 19
    • 0029004541 scopus 로고
    • Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia
    • Golub, T.R., Barker, G.F., Bohlander, S.K., et al. (1995) Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia. Proc. Natl. Acad. Sci. USA 92, 4917-4921.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 4917-4921
    • Golub, T.R.1    Barker, G.F.2    Bohlander, S.K.3
  • 20
    • 0039844411 scopus 로고    scopus 로고
    • Interaction and functional cooperation of PEBP2/CBF with Smads: Synergistic induction of the immunoglobulin germline Cα promoter
    • Hanai, J., Chen, L.F., Kanno, T., et al. (1999) Interaction and functional cooperation of PEBP2/CBF with Smads: Synergistic induction of the immunoglobulin germline Cα promoter. J. Biol. Chem. 274, 31577-31582.
    • (1999) J. Biol. Chem. , vol.274 , pp. 31577-31582
    • Hanai, J.1    Chen, L.F.2    Kanno, T.3
  • 21
    • 0029003504 scopus 로고
    • c-Myb and core-binding factor/PEBP2 display functional synergy but bind independently to adjacent sites in the T-cell receptor delta enhancer
    • Hernandez-Munain, C. & Krangel, M.S. (1995) c-Myb and core-binding factor/PEBP2 display functional synergy but bind independently to adjacent sites in the T-cell receptor delta enhancer. Mol. Cell. Biol. 15, 3090-3099.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 3090-3099
    • Hernandez-Munain, C.1    Krangel, M.S.2
  • 22
    • 0032983973 scopus 로고    scopus 로고
    • Core binding factor β revealed: Solution structure and map of the CBFα binding site
    • Huang, X., Peng, J.W., Speck, N.A. & Bushweller, J.H. (1999) Core binding factor β revealed: solution structure and map of the CBFα binding site. Nature Struct. Biol. 6, 624-627.
    • (1999) Nature Struct. Biol. , vol.6 , pp. 624-627
    • Huang, X.1    Peng, J.W.2    Speck, N.A.3    Bushweller, J.H.4
  • 23
    • 0001924796 scopus 로고
    • Interactions between the pairrule genes runt, hairy, even-skipped and fushi tarazu and the establishment of periodic pattern in Drosophila embryo
    • Ingham, P. & Gergen, P. (1988) Interactions between the pairrule genes runt, hairy, even-skipped and fushi tarazu and the establishment of periodic pattern in Drosophila embryo. Development 104 (Suppl.), 51-60.
    • (1988) Development , vol.104 , Issue.SUPPL. , pp. 51-60
    • Ingham, P.1    Gergen, P.2
  • 24
    • 0029866537 scopus 로고    scopus 로고
    • Structural alterations in the transcription factor PEBP2/CBF linked to four different types of leukemia
    • Ito, Y. (1996) Structural alterations in the transcription factor PEBP2/CBF linked to four different types of leukemia. J. Cancer Res. Clin. Oncol. 122, 266-274.
    • (1996) J. Cancer Res. Clin. Oncol. , vol.122 , pp. 266-274
    • Ito, Y.1
  • 25
    • 0000335533 scopus 로고    scopus 로고
    • The Runt domain transcription factor, PEBP2/CBF, and its involvement in human leukemia
    • ed. M. Karin, Cambridge, MA: Birkhauser
    • Ito, Y. & Bae, S.-C. (1997) The Runt domain transcription factor, PEBP2/CBF, and its involvement in human leukemia. In: Progress in Gene Expression (ed. M. Karin), pp. 107-132. Cambridge, MA: Birkhauser.
    • (1997) Progress in Gene Expression , pp. 107-132
    • Ito, Y.1    Bae, S.-C.2
  • 27
    • 12644307234 scopus 로고    scopus 로고
    • Functional dissection of the a and β subunits of transcription factor PEBP2 and the Redox susceptibility of its DNA binding activity
    • Kagoshima, H., Akamatsu, Y, Ito, Y & Shigesada, K. (1996) Functional dissection of the a and β subunits of transcription factor PEBP2 and the Redox susceptibility of its DNA binding activity. J. Biol. Chem. 271, 33074-33082.
    • (1996) J. Biol. Chem. , vol.271 , pp. 33074-33082
    • Kagoshima, H.1    Akamatsu, Y.2    Ito, Y.3    Shigesada, K.4
  • 28
    • 0025047508 scopus 로고
    • The Drosophila segmentation gene runt encodes a novel nuclear regulatory protein that is also expressed in the developing nervous system
    • Kania, M.A., Bonner, A.S., Duffy, J.B. & Gergen, J.P. (1990) The Drosophila segmentation gene runt encodes a novel nuclear regulatory protein that is also expressed in the developing nervous system. Genes Dev. 4, 1701-1713.
    • (1990) Genes Dev. , vol.4 , pp. 1701-1713
    • Kania, M.A.1    Bonner, A.S.2    Duffy, J.B.3    Gergen, J.P.4
  • 29
    • 0031940065 scopus 로고    scopus 로고
    • Intrinsic transcriptional activation/inhibition domains of the PEBP2/ CBF subunit revealed in the presence of the subunit
    • Kanno, T., Kanno, Y., Chen, L.-F., et al. (1998a) Intrinsic transcriptional activation/inhibition domains of the PEBP2/ CBF subunit revealed in the presence of the subunit. Mol. Cell. Biol. 18, 2444-2454.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 2444-2454
    • Kanno, T.1    Kanno, Y.2    Chen, L.-F.3
  • 30
    • 0031835437 scopus 로고    scopus 로고
    • Cytoplasmic sequenstration of the polyomavirus enhancer binding protein 2 (PEBP2)/core binding factor a (CBFa) subunit by the leukemia-related PEBP2/CBFβ-SMMHC fusion protein inhibits PEBP2/CBF-mediated transactivation
    • Kanno, Y., Kanno, T., Sakakura, C., Bae, S.-C. & Ito, Y (1998b) Cytoplasmic sequenstration of the polyomavirus enhancer binding protein 2 (PEBP2)/core binding factor a (CBFa) subunit by the leukemia-related PEBP2/CBFβ-SMMHC fusion protein inhibits PEBP2/CBF-mediated transactivation. Mol. Cell. Biol. 18, 4252-4261.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 4252-4261
    • Kanno, Y.1    Kanno, T.2    Sakakura, C.3    Bae, S.-C.4    Ito, Y.5
  • 31
    • 0033559972 scopus 로고    scopus 로고
    • Mutual activation of Ets-1 and AML1 DNA binding by direct interaction of their autoinhibitory domains
    • Kim, W.-Y., Sieweke, M., Ogawa, E., et al. (1999) Mutual activation of Ets-1 and AML1 DNA binding by direct interaction of their autoinhibitory domains. EMBO J. 18, 1609-1620.
    • (1999) EMBO J. , vol.18 , pp. 1609-1620
    • Kim, W.-Y.1    Sieweke, M.2    Ogawa, E.3
  • 32
    • 0032101379 scopus 로고    scopus 로고
    • Interaction and functional cooperation of the leukemia-associated factors AML1 and p300 in myeloid cell differentiation
    • Kitabayashi, I., Yokoyama, A., Shimizu, K. & Ohki, M. (1998a) Interaction and functional cooperation of the leukemia-associated factors AML1 and p300 in myeloid cell differentiation. EMBO J. 17, 2994-3004.
    • (1998) EMBO J. , vol.17 , pp. 2994-3004
    • Kitabayashi, I.1    Yokoyama, A.2    Shimizu, K.3    Ohki, M.4
  • 33
    • 0031883569 scopus 로고    scopus 로고
    • The AML1-MTG8 leukemic fusion protein forms a complex with a novel member of the MTG8 (ETO/CDR) family, MTGR1
    • Kitabayashi, I., Ida, K., Morohoshi, F., et al. (1998b) The AML1-MTG8 leukemic fusion protein forms a complex with a novel member of the MTG8 (ETO/CDR) family, MTGR1. Mol. Cell. Biol. 18, 846-858.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 846-858
    • Kitabayashi, I.1    Ida, K.2    Morohoshi, F.3
  • 34
    • 0030684749 scopus 로고    scopus 로고
    • Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts
    • Komori, T., Yagi, H., Nomura, S., et al. (1997) Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell 89, 755-764.
    • (1997) Cell , vol.89 , pp. 755-764
    • Komori, T.1    Yagi, H.2    Nomura, S.3
  • 35
    • 0030927622 scopus 로고    scopus 로고
    • Missense mutation abolishing DNA binding of the osteoblast-specific transcription factor OSF2/CBFA1 in cleidocranial dysplasia
    • Lee, B., Thirunavukkarasu, K., Zhou, L., et al. (1997) Missense mutation abolishing DNA binding of the osteoblast-specific transcription factor OSF2/CBFA1 in cleidocranial dysplasia. Nature Genet. 16, 307-310.
    • (1997) Nature Genet. , vol.16 , pp. 307-310
    • Lee, B.1    Thirunavukkarasu, K.2    Zhou, L.3
  • 36
    • 0021029085 scopus 로고
    • A putative second cell-derived oncogene of the avian leukaemia retrovirus E26
    • Leprince, D., Gegonne, A., Coll, J., et al. (1983) A putative second cell-derived oncogene of the avian leukaemia retrovirus E26. Nature 306, 395-397.
    • (1983) Nature , vol.306 , pp. 395-397
    • Leprince, D.1    Gegonne, A.2    Coll, J.3
  • 37
    • 0028136578 scopus 로고
    • AML1, AML2, and AML3, the human members of the runt domain gene-family: CDNA structure, expression, and chromosomal localization
    • Levanon, D., Negreanu, V., Bernstein, Y., et al. (1994) AML1, AML2, and AML3, the human members of the runt domain gene-family: cDNA structure, expression, and chromosomal localization. Genomics 23, 425-432.
    • (1994) Genomics , vol.23 , pp. 425-432
    • Levanon, D.1    Negreanu, V.2    Bernstein, Y.3
  • 38
    • 0030658039 scopus 로고    scopus 로고
    • Oncogenic transcription factors in the human acute leukemias
    • Look, A.T. (1997) Oncogenic transcription factors in the human acute leukemias. Science 278, 1059-1064.
    • (1997) Science , vol.278 , pp. 1059-1064
    • Look, A.T.1
  • 39
    • 0028839054 scopus 로고
    • Subcellular localization of the a and β subunits of the acute myeloid leukemia-linked transcription factor PEBP2/CBF
    • Lu, J., Maruyama, M., Satake, M., et al. (1995) Subcellular localization of the a and β subunits of the acute myeloid leukemia-linked transcription factor PEBP2/CBF. Mol. Cell. Biol. 15, 1651-1661.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 1651-1661
    • Lu, J.1    Maruyama, M.2    Satake, M.3
  • 40
    • 0030943424 scopus 로고    scopus 로고
    • Distinct roles for P-CREB and LEF-1 in TCR-α enhancer assembly and activation on chromatin templates in vitro
    • Mayall, T.P., Sheridan, P.L., Montminy, M.R. & Jones, K.A. (1997) Distinct roles for P-CREB and LEF-1 in TCR-α enhancer assembly and activation on chromatin templates in vitro. Genes Dev. 11, 887-899.
    • (1997) Genes Dev. , vol.11 , pp. 887-899
    • Mayall, T.P.1    Sheridan, P.L.2    Montminy, M.R.3    Jones, K.A.4
  • 41
    • 0030595341 scopus 로고    scopus 로고
    • Definitive hematopoiesis is autonomously initiated by the AGM region
    • Medvinsky, A. & Dzierzak, E. (1996) Definitive hematopoiesis is autonomously initiated by the AGM region. Cell 86, 897-906.
    • (1996) Cell , vol.86 , pp. 897-906
    • Medvinsky, A.1    Dzierzak, E.2
  • 42
    • 0028069226 scopus 로고
    • Generation of the AML1-EV1-1 fusion gene in the t(3;21) (q26;q22) causes blastic crisis in chronic myelocytic leukemia
    • Mitani, K., Ogawa, S., Tanaka, T., et al. (1994) Generation of the AML1-EV1-1 fusion gene in the t(3;21) (q26;q22) causes blastic crisis in chronic myelocytic leukemia. EMBO J. 13, 504-510.
    • (1994) EMBO J. , vol.13 , pp. 504-510
    • Mitani, K.1    Ogawa, S.2    Tanaka, T.3
  • 43
    • 0025746321 scopus 로고
    • t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene AML1
    • Miyoshi, H., Shimizu, K., Kozu, T., et al. (1991) t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene AML1. Proc. Natl. Acad. Sci. USA 88, 10431-10434.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 10431-10434
    • Miyoshi, H.1    Shimizu, K.2    Kozu, T.3
  • 44
    • 0028891018 scopus 로고
    • Genetic mapping of cleidocranial dysplasia and evidence of a mircodeletion in one family
    • Mundlos, S., Mulliken, J.B., Abramson, D.L., et al. (1995) Genetic mapping of cleidocranial dysplasia and evidence of a mircodeletion in one family. Hum. Mol Genet. 4, 71-75.
    • (1995) Hum. Mol Genet. , vol.4 , pp. 71-75
    • Mundlos, S.1    Mulliken, J.B.2    Abramson, D.L.3
  • 46
    • 15444351110 scopus 로고    scopus 로고
    • Mutation involving the transcription factor CBFA1 cause cleidocranial dysplasia
    • Mundlos, S., Otto, F. & Mundlos, C. (1997) Mutation involving the transcription factor CBFA1 cause cleidocranial dysplasia. Cell 89, 773-779.
    • (1997) Cell , vol.89 , pp. 773-779
    • Mundlos, S.1    Otto, F.2    Mundlos, C.3
  • 47
    • 0032984118 scopus 로고    scopus 로고
    • Immunoglobulin motif DNA recognition and heterodimerization for the PEBP2/CBF Runt-domain
    • Nagata, T., Gupta, V., Kim, W.-Y., et al (1999) Immunoglobulin motif DNA recognition and heterodimerization for the PEBP2/CBF Runt-domain. Nature Struct. Biol. 6, 615-619.
    • (1999) Nature Struct. Biol. , vol.6 , pp. 615-619
    • Nagata, T.1    Gupta, V.2    Kim, W.-Y.3
  • 48
    • 0030915268 scopus 로고    scopus 로고
    • Hematopoiesis in the fetal liver is impaired by targeted mutagenesis of a gene encoding a non-DNA binding subunit of the transcription factor, PEPB2/CBF
    • Niki, M., Okada, H., Takano, H., et al. (1997) Hematopoiesis in the fetal liver is impaired by targeted mutagenesis of a gene encoding a non-DNA binding subunit of the transcription factor, PEPB2/CBF. Proc. Natl. Acad. Sci. USA 4, 5697-5702.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.4 , pp. 5697-5702
    • Niki, M.1    Okada, H.2    Takano, H.3
  • 49
    • 0033036971 scopus 로고    scopus 로고
    • Cbfa2 is required for the formation of intra-aortic hematopoietic clusters
    • North, T.E., Gu, T.-L., Stacy, T., et al. (1999) Cbfa2 is required for the formation of intra-aortic hematopoietic clusters. Development 126, 2563-2575.
    • (1999) Development , vol.126 , pp. 2563-2575
    • North, T.E.1    Gu, T.-L.2    Stacy, T.3
  • 50
    • 0027183945 scopus 로고
    • The 3; 21 translocation in myelodysplasia results in fusion transcript between the AML1 gene and the gene for EAP, a highly conserved protein associated with the Epstein-Barr virus small RNA EBER 1
    • Nucifora, G., Begy, C.R., Erickson, P., Drabkin, H.A. & Rowley, J.D. (1993) The 3; 21 translocation in myelodysplasia results in fusion transcript between the AML1 gene and the gene for EAP, a highly conserved protein associated with the Epstein-Barr virus small RNA EBER 1. Proc. Natl. Acad. Sci. USA 90, 7784-7788.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 7784-7788
    • Nucifora, G.1    Begy, C.R.2    Erickson, P.3    Drabkin, H.A.4    Rowley, J.D.5
  • 51
    • 0021056037 scopus 로고
    • Tripartite structure of the avian erythroblastosis virus E26 transforming gene
    • Nunn, M.E, Seeburg, PH., Moscovic, C. & Duesberg, P.H. (1983) Tripartite structure of the avian erythroblastosis virus E26 transforming gene. Nature 306, 391-395.
    • (1983) Nature , vol.306 , pp. 391-395
    • Nunn, M.E.1    Seeburg, P.H.2    Moscovic, C.3    Duesberg, P.H.4
  • 52
    • 0027184229 scopus 로고
    • Molecular cloning and characterization of PEBP2β, the heterodimeric partner of a novel Drosophila runt-related DNA binding protein PEBP2α
    • Ogawa, E., Inuzuka, M., Maruyama, M., et al. (1993a) Molecular cloning and characterization of PEBP2β, the heterodimeric partner of a novel Drosophila runt-related DNA binding protein PEBP2α. Virology 194, 314-331.
    • (1993) Virology , vol.194 , pp. 314-331
    • Ogawa, E.1    Inuzuka, M.2    Maruyama, M.3
  • 53
    • 0027220003 scopus 로고
    • PEBP2/PEA2 represents a family of transcription factors - Homologous to the products of the Drosophila rant gene and the human AML1 gene
    • Ogawa, E., Maruyama, M., Kagoshima, H., et al. (1993b) PEBP2/PEA2 represents a family of transcription factors - homologous to the products of the Drosophila rant gene and the human AML1 gene. Proc. Natl. Acad. Sci. USA 90, 6859-6863.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 6859-6863
    • Ogawa, E.1    Maruyama, M.2    Kagoshima, H.3
  • 54
    • 0033549843 scopus 로고    scopus 로고
    • Synergy of PEBP2/CBF with mi transcription factor (MITF) for transactivation of mouse mast cell protease 6 gene
    • Ogihara, H., Kanno, T., Morii, E., et al. (1999) Synergy of PEBP2/CBF with mi transcription factor (MITF) for transactivation of mouse mast cell protease 6 gene. Oncogene 18, 4632-4639.
    • (1999) Oncogene , vol.18 , pp. 4632-4639
    • Ogihara, H.1    Kanno, T.2    Morii, E.3
  • 55
    • 0030061554 scopus 로고    scopus 로고
    • AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis
    • Okuda, T., van Deursen, J., Hiebert, S.W., Grosveld, G. & Downing, J.R. (1996) AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis. Cell 84, 321-330.
    • (1996) Cell , vol.84 , pp. 321-330
    • Okuda, T.1    Van Deursen, J.2    Hiebert, S.W.3    Grosveld, G.4    Downing, J.R.5
  • 56
    • 0033559746 scopus 로고    scopus 로고
    • Biallelic and heterozygous point mutations in the Runt domain of the AML1/PEBP2aB gene associated with myeloblastic leukemias
    • Osato, M., Asou, N., Abdalla, E., et al. (1999) Biallelic and heterozygous point mutations in the Runt domain of the AML1/PEBP2aB gene associated with myeloblastic leukemias. Blood 93, 1817-1824.
    • (1999) Blood , vol.93 , pp. 1817-1824
    • Osato, M.1    Asou, N.2    Abdalla, E.3
  • 57
    • 0030666372 scopus 로고    scopus 로고
    • Cbfa1, a candidate gene for Cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development
    • Otto, F., Thornell, A.P., Crompton, T., et al. (1997) Cbfa1, a candidate gene for Cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development. Cell 89, 765-772.
    • (1997) Cell , vol.89 , pp. 765-772
    • Otto, F.1    Thornell, A.P.2    Crompton, T.3
  • 59
    • 0030690556 scopus 로고    scopus 로고
    • The missing bone
    • Rodan, G.A. & Harada, S. (1997) The missing bone. Cell 89, 677-680.
    • (1997) Cell , vol.89 , pp. 677-680
    • Rodan, G.A.1    Harada, S.2
  • 60
    • 0029973591 scopus 로고    scopus 로고
    • Absence of fetal liver hematopoiesis in transcriptional co-activator, core binding factor β (Cbfβ) deficient mice
    • Sasaki, K., Yagi, H., Bronsonm, R.T., et al. (1996) Absence of fetal liver hematopoiesis in transcriptional co-activator, core binding factor β (Cbfβ) deficient mice. Proc. Natl. Acad. Sci. USA 93, 12359-12363.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 12359-12363
    • Sasaki, K.1    Yagi, H.2    Bronsonm, R.T.3
  • 61
    • 0028804629 scopus 로고
    • Expression of the Runt domain-coding PEBP2α genes in T cell during thymic development
    • Satake, M., Nomura, S., Iwai-Yamaguchi, Y., et al. (1995) Expression of the Runt domain-coding PEBP2α genes in T cell during thymic development. Mol. Cell. Biol. 15, 1662-1670.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 1662-1670
    • Satake, M.1    Nomura, S.2    Iwai-Yamaguchi, Y.3
  • 62
    • 7844235808 scopus 로고    scopus 로고
    • Transcriptional regulation of osteopontin gene in vivo by PEBP2αA/CBFA1 and ETS1 in the skeletal tissues
    • Sato, M., Morii, E., Komori, T., et al. (1998) Transcriptional regulation of osteopontin gene in vivo by PEBP2αA/CBFA1 and ETS1 in the skeletal tissues. Oncogene 17, 1517-1525.
    • (1998) Oncogene , vol.17 , pp. 1517-1525
    • Sato, M.1    Morii, E.2    Komori, T.3
  • 63
    • 0032534230 scopus 로고    scopus 로고
    • CBF α3 (AML2) is induced by TGF-β to bind and activate the mouse germiline Ig α promoter
    • Shi, M.J. & Stavnezer, J. (1998) CBF α3 (AML2) is induced by TGF-β to bind and activate the mouse germiline Ig α promoter. J. Immunol 161, 6751-6760.
    • (1998) J. Immunol , vol.161 , pp. 6751-6760
    • Shi, M.J.1    Stavnezer, J.2
  • 64
    • 0032190631 scopus 로고    scopus 로고
    • Dynamic change of transcription factor interactions in blood cell differentiation: A cocktail party scenario
    • Sieweke, M.H. & Graf, T. (1998) Dynamic change of transcription factor interactions in blood cell differentiation: a cocktail party scenario. Curr. Opin. Genet. Develop. 8, 545-551.
    • (1998) Curr. Opin. Genet. Develop. , vol.8 , pp. 545-551
    • Sieweke, M.H.1    Graf, T.2
  • 65
    • 0033118155 scopus 로고    scopus 로고
    • Core-binding factor: A central player in hematopoiesis and leukemia
    • Speck, N.A., Stacy, T., Wang, Q., et al. (1999) Core-binding factor: a central player in hematopoiesis and leukemia. Cancer Res. 59, 1789s-1793s.
    • (1999) Cancer Res. , vol.59
    • Speck, N.A.1    Stacy, T.2    Wang, Q.3
  • 66
    • 0024003840 scopus 로고    scopus 로고
    • 3 , a Drosophila mutant lacking basiconic antennal sensilla
    • 3 , a Drosophila mutant lacking basiconic antennal sensilla. Dev. Biol. 127, 12-27.
    • (1998) Dev. Biol. , vol.127 , pp. 12-27
    • Stocker, F.R.1    Gendre, N.2
  • 67
    • 0028943758 scopus 로고
    • Dual functions of the AML1/Evi-1 chimeric protein in the mechanism of leukemogenesis in t(3;21) leukemias
    • Tanaka, T., Mitani, K., Kurokawa, M., et al. (1995a) Dual functions of the AML1/Evi-1 chimeric protein in the mechanism of leukemogenesis in t(3;21) leukemias. Mol. Cell. Biol. 15, 2383-2392.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 2383-2392
    • Tanaka, T.1    Mitani, K.2    Kurokawa, M.3
  • 68
    • 0028837972 scopus 로고
    • An acute myeloid leukemia gene, AML1, regulates hemopoietic myeloid cell differentiation and transcriptional activation antagonistically by two alternative spliced forms
    • Tanaka, T., Tanaka, K., Ogawa, S., et al. (1995b) An acute myeloid leukemia gene, AML1, regulates hemopoietic myeloid cell differentiation and transcriptional activation antagonistically by two alternative spliced forms. EMBO J. 14, 341-350.
    • (1995) EMBO J. , vol.14 , pp. 341-350
    • Tanaka, T.1    Tanaka, K.2    Ogawa, S.3
  • 69
    • 8944230662 scopus 로고    scopus 로고
    • The extracellular signal-regulated kinase pathway phosphorylates AML1, an acute myeloid leukemia gene product, and potentially regulates its transactivation ability
    • Tanaka, T., Kurokawa, M., Ueki, K., et al. (1996) The extracellular signal-regulated kinase pathway phosphorylates AML1, an acute myeloid leukemia gene product, and potentially regulates its transactivation ability. Mol. Cell. Biol. 16, 3967-3979.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 3967-3979
    • Tanaka, T.1    Kurokawa, M.2    Ueki, K.3
  • 70
    • 0029918597 scopus 로고    scopus 로고
    • Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis
    • Wang, Q., Stacy, T., Bindr, M., et al. (1996a) Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis. Proc. Natl. Acad. Sci. USA 93, 3444-3449.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 3444-3449
    • Wang, Q.1    Stacy, T.2    Bindr, M.3
  • 71
    • 0030588487 scopus 로고    scopus 로고
    • The CBFβ subunit is essential for CBFα2 (AML1) function in vivo
    • Wang, Q., Stacy, T., Miller, J.D., et al. (1996b) The CBFβ subunit is essential for CBFα2 (AML1) function in vivo. Cell 87, 697-708.
    • (1996) Cell , vol.87 , pp. 697-708
    • Wang, Q.1    Stacy, T.2    Miller, J.D.3
  • 72
    • 0027256023 scopus 로고
    • Cloning and characterization of subunits of the T-cell receptor and murine leukemia virus enhancer core-binding factor
    • Wang, S., Wang, Q., Crute, B.E., et al. (1993) Cloning and characterization of subunits of the T-cell receptor and murine leukemia virus enhancer core-binding factor. Mol Cell. Biol. 13, 3324-3339.
    • (1993) Mol Cell. Biol. , vol.13 , pp. 3324-3339
    • Wang, S.1    Wang, Q.2    Crute, B.E.3
  • 73
    • 0033522472 scopus 로고    scopus 로고
    • A WW domain-containing Yes-associated protein (YAP) is a novel transcriptional co-activator
    • Yagi, R., Chen, L.-F., Shigesada, K., Murakami, Y. & Ito, Y. (1999) A WW domain-containing Yes-associated protein (YAP) is a novel transcriptional co-activator. EMBO J. 18, 2551-2562.
    • (1999) EMBO J. , vol.18 , pp. 2551-2562
    • Yagi, R.1    Chen, L.-F.2    Shigesada, K.3    Murakami, Y.4    Ito, Y.5
  • 74
    • 0030879733 scopus 로고    scopus 로고
    • Characterization of definitive lymphohematopoietic stem sells in the day 9 murine yolk sac
    • Yoder, M.C., Hiatt, K., Dutt, P., et al. (1997) Characterization of definitive lymphohematopoietic stem sells in the day 9 murine yolk sac. Immunity 7, 335-344.
    • (1997) Immunity , vol.7 , pp. 335-344
    • Yoder, M.C.1    Hiatt, K.2    Dutt, P.3
  • 75
    • 0027984233 scopus 로고
    • Identification of a region which directs the monocytic activity of the colony-stimulating factor 1 (macrophage colonystimulating factor) receptor promoter and binds PLBP2/ CBF (AML1)
    • Zhang, D.E., Fujioka, K., Hetherington, C.J., et al. (1994) Identification of a region which directs the monocytic activity of the colony-stimulating factor 1 (macrophage colonystimulating factor) receptor promoter and binds PLBP2/ CBF (AML1). Mol. Cell. Biol. 14, 8085-8095.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 8085-8095
    • Zhang, D.E.1    Fujioka, K.2    Hetherington, C.J.3
  • 76
    • 0030024112 scopus 로고    scopus 로고
    • CCAAT enhancer-binding protein (C/LBP) and AML1 macrophage colony-stimulating factor receptor promoter
    • Zhang, D.E., Hetherington, C.J., Meyers, S., et al. (1996) CCAAT enhancer-binding protein (C/LBP) and AML1 macrophage colony-stimulating factor receptor promoter. Mol. Cell. Biol. 16, 1231-1240.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 1231-1240
    • Zhang, D.E.1    Hetherington, C.J.2    Meyers, S.3
  • 77
    • 0030755242 scopus 로고    scopus 로고
    • The cDNA cloning of the transcripts of human PLBP2αA/CBFA1 mapped to 6p12.3-p21.1, the locus for cleidocranial dysplasia
    • Zhang, Y-W., Bae, S.-C., Takahashi, E. & Ito, Y (1997) The cDNA cloning of the transcripts of human PLBP2αA/CBFA1 mapped to 6p12.3-p21.1, the locus for cleidocranial dysplasia. Oncogene 15, 367-371.
    • (1997) Oncogene , vol.15 , pp. 367-371
    • Zhang, Y.-W.1    Bae, S.-C.2    Takahashi, E.3    Ito, Y.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.