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Volumn 24, Issue 13, 2004, Pages 5639-5649

Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; GUANINE NUCLEOTIDE BINDING PROTEIN; HISTONE METHYLTRANSFERASE; HOST CELL FACTOR 1; HOST CELL FACTOR 2; METHYLTRANSFERASE; MIXED LINEAGE LEUKEMIA PROTEIN; PROTEIN; PROTEIN ASH 2; PROTEIN MENIN; PROTEIN P300; PROTEIN SET1; TRANSCRIPTION FACTOR; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

EID: 2942715029     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.24.13.5639-5649.2004     Document Type: Article
Times cited : (553)

References (69)
  • 1
    • 0028861418 scopus 로고
    • The PHD finger: Implications for chromatin-mediated transcriptional regulation
    • Aasland, R., T. J. Gibson, and A. F. Stewart. 1995. The PHD finger: implications for chromatin-mediated transcriptional regulation. Trends Biochem. Sci. 20:56-59.
    • (1995) Trends Biochem. Sci. , vol.20 , pp. 56-59
    • Aasland, R.1    Gibson, T.J.2    Stewart, A.F.3
  • 4
    • 0037138359 scopus 로고    scopus 로고
    • SET-domain proteins of the Su(var)3-9, E(z) and trithorax families
    • Alvarez-Venegas, R., and Z. Avramova. 2002. SET-domain proteins of the Su(var)3-9, E(z) and trithorax families. Gene 285:25-37.
    • (2002) Gene , vol.285 , pp. 25-37
    • Alvarez-Venegas, R.1    Avramova, Z.2
  • 6
    • 0035839952 scopus 로고    scopus 로고
    • Molecular mechanisms of leukemogenesis mediated by MLL fusion proteins
    • Ayton, P. M., and M. L. Cleary. 2001. Molecular mechanisms of leukemogenesis mediated by MLL fusion proteins. Oncogene 20:5695-5707.
    • (2001) Oncogene , vol.20 , pp. 5695-5707
    • Ayton, P.M.1    Cleary, M.L.2
  • 7
    • 0041370095 scopus 로고    scopus 로고
    • Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9
    • Ayton, P. M., and M. L. Cleary. 2003. Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9. Genes Dev. 17:2298-2307.
    • (2003) Genes Dev. , vol.17 , pp. 2298-2307
    • Ayton, P.M.1    Cleary, M.L.2
  • 8
    • 0027536183 scopus 로고
    • Trithorax regulates multiple homeotic genes in the bithorax and antennapedia complexes and exerts different tissue-specific, parasegment-specific and promoter-specific effects on each
    • Breen, T. R., and P. J. Harte. 1993. Trithorax regulates multiple homeotic genes in the bithorax and antennapedia complexes and exerts different tissue-specific, parasegment-specific and promoter-specific effects on each. Development 117:119-134.
    • (1993) Development , vol.117 , pp. 119-134
    • Breen, T.R.1    Harte, P.J.2
  • 9
    • 0030905542 scopus 로고    scopus 로고
    • The HRX proto-oncogene product is widely expressed in human tissues and localizes to nuclear structures
    • Butler, L. H., R. Slany, X. Cui, M. L. Cleary, and D. Y. Mason. 1997. The HRX proto-oncogene product is widely expressed in human tissues and localizes to nuclear structures. Blood 89:3361-3370.
    • (1997) Blood , vol.89 , pp. 3361-3370
    • Butler, L.H.1    Slany, R.2    Cui, X.3    Cleary, M.L.4    Mason, D.Y.5
  • 11
    • 0038695861 scopus 로고    scopus 로고
    • Functional studies of the MEN1 gene
    • Chandrasekharappa, S. C., and B. T. Teh. 2003. Functional studies of the MEN1 gene. J. Intern. Med. 253:606-615.
    • (2003) J. Intern. Med. , vol.253 , pp. 606-615
    • Chandrasekharappa, S.C.1    Teh, B.T.2
  • 12
    • 0036730163 scopus 로고    scopus 로고
    • The promiscuous MLL gene links chromosomal translocations to cellular diferentiation and tumour tropism
    • Collins, E. C., and T. H. Rabbitts. 2002. The promiscuous MLL gene links chromosomal translocations to cellular diferentiation and tumour tropism. Trends Mol. Med. 8:436-442.
    • (2002) Trends Mol. Med. , vol.8 , pp. 436-442
    • Collins, E.C.1    Rabbitts, T.H.2
  • 13
    • 0031945475 scopus 로고    scopus 로고
    • Association of SET domain and myotubularin-related proteins modulates growth control
    • Cui, X., I. De Vivo, R. Slany, A. Miyamoto, R. Firestein, and M. L. Cleary. 1998. Association of SET domain and myotubularin-related proteins modulates growth control. Nat. Genet. 18:331-337.
    • (1998) Nat. Genet. , vol.18 , pp. 331-337
    • Cui, X.1    De Vivo, I.2    Slany, R.3    Miyamoto, A.4    Firestein, R.5    Cleary, M.L.6
  • 14
    • 0032831130 scopus 로고    scopus 로고
    • Mll rearrangements in haematological malignancies: Lessons from clinical and biological studies
    • Dimartino, J. F., and M. L. Cleary. 1999. Mll rearrangements in haematological malignancies: lessons from clinical and biological studies. Br. J. Haematol. 106:614-626.
    • (1999) Br. J. Haematol. , vol.106 , pp. 614-626
    • Dimartino, J.F.1    Cleary, M.L.2
  • 15
    • 0026936328 scopus 로고
    • A trithorax-like gene is interrupted by chromosome 11q23 translocations in acute leukaemias
    • Djabali, M., L. Selleri, P. Parry, M. Bower, B. D. Young, and G. A. Evans. 1992. A trithorax-like gene is interrupted by chromosome 11q23 translocations in acute leukaemias. Nat. Genet. 2:113-118.
    • (1992) Nat. Genet. , vol.2 , pp. 113-118
    • Djabali, M.1    Selleri, L.2    Parry, P.3    Bower, M.4    Young, B.D.5    Evans, G.A.6
  • 16
    • 0035102477 scopus 로고    scopus 로고
    • MLL and CREB bind cooperatively to the nuclear coactivator CREB-binding protein
    • Ernst, P., J. Wang, M. Huang, R. H. Goodman, and S. J. Korsmeyer. 2001. MLL and CREB bind cooperatively to the nuclear coactivator CREB-binding protein. Mol. Cell. Biol. 21:2249-2258.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 2249-2258
    • Ernst, P.1    Wang, J.2    Huang, M.3    Goodman, R.H.4    Korsmeyer, S.J.5
  • 17
    • 0034122096 scopus 로고    scopus 로고
    • SET domain-dependent regulation of transcriptional silencing and growth control by SUV39H1, a mammalian ortholog of Drosophila Su(var)3-9
    • Firestein, R., X. Cui, P. Huie, and M. L. Cleary. 2000. SET domain-dependent regulation of transcriptional silencing and growth control by SUV39H1, a mammalian ortholog of Drosophila Su(var)3-9. Mol. Cell. Biol. 20:4900-4909.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 4900-4909
    • Firestein, R.1    Cui, X.2    Huie, P.3    Cleary, M.L.4
  • 18
    • 0030687635 scopus 로고    scopus 로고
    • Viral mimicry: Common mode of association with HCF by VP16 and the cellular protein LZIP
    • Freiman, R. N., and W. Herr. 1997. Viral mimicry: common mode of association with HCF by VP16 and the cellular protein LZIP. Genes Dev. 11:3122-3127.
    • (1997) Genes Dev. , vol.11 , pp. 3122-3127
    • Freiman, R.N.1    Herr, W.2
  • 20
    • 1442348168 scopus 로고    scopus 로고
    • BIG-3, a novel WD-40 repeat protein, is expressed in the developing growth plate and accelerates chondrocyte differentiation in vitro
    • Gori, F., and M. B. Demay. 2004. BIG-3, a novel WD-40 repeat protein, is expressed in the developing growth plate and accelerates chondrocyte differentiation in vitro. Endocrinology 145:1050-1054.
    • (2004) Endocrinology , vol.145 , pp. 1050-1054
    • Gori, F.1    Demay, M.B.2
  • 22
    • 0026496887 scopus 로고
    • The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene
    • Gu, Y., T. Nakamura, H. Alder, R. Prasad, O. Canaani, G. Cimino, C. M. Croce, and E. Canaani. 1992. The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene. Cell 71:701-708.
    • (1992) Cell , vol.71 , pp. 701-708
    • Gu, Y.1    Nakamura, T.2    Alder, H.3    Prasad, R.4    Canaani, O.5    Cimino, G.6    Croce, C.M.7    Canaani, E.8
  • 24
    • 0345276803 scopus 로고    scopus 로고
    • Taspase1: A threonine aspartase required for cleavage of MLL and proper HOX gene expression
    • Hsieh, J. J., E. H. Cheng, and S. J. Korsmeyer. 2003. Taspase1: a threonine aspartase required for cleavage of MLL and proper HOX gene expression. Cell 115:293-303.
    • (2003) Cell , vol.115 , pp. 293-303
    • Hsieh, J.J.1    Cheng, E.H.2    Korsmeyer, S.J.3
  • 25
    • 0037215399 scopus 로고    scopus 로고
    • Proteolytic cleavage of MLL generates a complex of N- and C-terminal fragments that confers protein stability and subnuclear localization
    • Hsieh, J. J., P. Ernst, H. Erdjument-Bromage, P. Tempst, and S. J. Korsmeyer. 2003. Proteolytic cleavage of MLL generates a complex of N- and C-terminal fragments that confers protein stability and subnuclear localization. Mol. Cell. Biol. 23:186-194.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 186-194
    • Hsieh, J.J.1    Ernst, P.2    Erdjument-Bromage, H.3    Tempst, P.4    Korsmeyer, S.J.5
  • 26
    • 0041883660 scopus 로고    scopus 로고
    • Turning on a dimer: New insights into MLL chimeras
    • Hsu, K., and A. T. Look. 2003. Turning on a dimer: new insights into MLL chimeras. Cancer Cell 4:81-83.
    • (2003) Cancer Cell , vol.4 , pp. 81-83
    • Hsu, K.1    Look, A.T.2
  • 28
    • 0034970067 scopus 로고    scopus 로고
    • An atlas of chromosomes in hematological malignancies. Example: 11q23 and MLL partners
    • Huret, J. L., P. Dessen, and A. Bernheim. 2001. An atlas of chromosomes in hematological malignancies. Example: 11q23 and MLL partners. Leukemia 15:987-989.
    • (2001) Leukemia , vol.15 , pp. 987-989
    • Huret, J.L.1    Dessen, P.2    Bernheim, A.3
  • 29
    • 0033014011 scopus 로고    scopus 로고
    • Cloning and characterization of ASH2L and Ash21, human and mouse homologs of the Drosophila ash2 gene
    • Ikegawa, S., M. Isomura, Y. Koshizuka, and Y. Nakamura. 1999. Cloning and characterization of ASH2L and Ash21, human and mouse homologs of the Drosophila ash2 gene. Cytogenet. Cell Genet. 84:167-172.
    • (1999) Cytogenet. Cell Genet. , vol.84 , pp. 167-172
    • Ikegawa, S.1    Isomura, M.2    Koshizuka, Y.3    Nakamura, Y.4
  • 31
    • 0032897973 scopus 로고    scopus 로고
    • Herpes simplex virus transactivator VP16 discriminates between HCF-1 and a novel family member, HCF-2
    • Johnson, K. M., S. S. Mahajan, and A. C. Wilson. 1999. Herpes simplex virus transactivator VP16 discriminates between HCF-1 and a novel family member, HCF-2. J. Virol. 73:3930-3940.
    • (1999) J. Virol. , vol.73 , pp. 3930-3940
    • Johnson, K.M.1    Mahajan, S.S.2    Wilson, A.C.3
  • 32
    • 0141885136 scopus 로고    scopus 로고
    • Menin, a tumor suppressor, represses JunD-mediated transcriptional activity by association with an mSin3A-histone deacetylase complex
    • Kim, H., J. E. Lee, E. J. Cho, J. O. Liu, and H. D. Youn. 2003. Menin, a tumor suppressor, represses JunD-mediated transcriptional activity by association with an mSin3A-histone deacetylase complex. Cancer Res. 63:6135-6139.
    • (2003) Cancer Res. , vol.63 , pp. 6135-6139
    • Kim, H.1    Lee, J.E.2    Cho, E.J.3    Liu, J.O.4    Youn, H.D.5
  • 33
    • 0028904801 scopus 로고
    • The cellular C1 factor of the herpes simplex virus enhancer complex is a family of polypeptides
    • Kristie, T. M., J. L. Pomerantz, T. C. Twomey, S. A. Parent, and P. A. Sharp. 1995. The cellular C1 factor of the herpes simplex virus enhancer complex is a family of polypeptides. J. Biol. Chem. 270:4387-4394.
    • (1995) J. Biol. Chem. , vol.270 , pp. 4387-4394
    • Kristie, T.M.1    Pomerantz, J.L.2    Twomey, T.C.3    Parent, S.A.4    Sharp, P.A.5
  • 34
    • 1442356858 scopus 로고    scopus 로고
    • Hoxa9 influences the phenotype but not the incidence of M11-AF9 fusion gene leukemia
    • Kumar, A. R., W. A. Hudson, W. Chen, R. Nishiuchi, Q. Yao, and J. H. Kersey. 2003. Hoxa9 influences the phenotype but not the incidence of M11-AF9 fusion gene leukemia. Blood 100:1823-1828.
    • (2003) Blood , vol.100 , pp. 1823-1828
    • Kumar, A.R.1    Hudson, W.A.2    Chen, W.3    Nishiuchi, R.4    Yao, Q.5    Kersey, J.H.6
  • 35
    • 0037111831 scopus 로고    scopus 로고
    • Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein
    • Kuzmichev, A., K. Nishioka, H. Erdjument-Bromage, P. Tempst, and D. Reinberg. 2002. Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein. Genes Dev. 16:2893-2905.
    • (2002) Genes Dev. , vol.16 , pp. 2893-2905
    • Kuzmichev, A.1    Nishioka, K.2    Erdjument-Bromage, H.3    Tempst, P.4    Reinberg, D.5
  • 36
    • 0029121550 scopus 로고
    • Trans-regulation of thoracic homeotic selector genes of the antennapedia and bithorax complexes by the trithorax group genes: Absent, small, and homeotic discs 1 and 2
    • LaJeunesse, D., and A. Shearn. 1995. Trans-regulation of thoracic homeotic selector genes of the antennapedia and bithorax complexes by the trithorax group genes: absent, small, and homeotic discs 1 and 2. Mech. Dev. 53:123-139.
    • (1995) Mech. Dev. , vol.53 , pp. 123-139
    • LaJeunesse, D.1    Shearn, A.2
  • 37
    • 0037821661 scopus 로고    scopus 로고
    • Multiple tumor suppressor pathways negatively regulate telomerase
    • Lin, S. Y., and S. J. Elledge. 2003. Multiple tumor suppressor pathways negatively regulate telomerase. Cell 113:881-889.
    • (2003) Cell , vol.113 , pp. 881-889
    • Lin, S.Y.1    Elledge, S.J.2
  • 38
    • 0031878579 scopus 로고    scopus 로고
    • The herpesvirus transactivator VP16 mimics a human basic domain leucine zipper protein, luman, in its interaction with HCF
    • Lu, R., P. Yang, S. Padmakumar, and V. Misra. 1998. The herpesvirus transactivator VP16 mimics a human basic domain leucine zipper protein, luman, in its interaction with HCF. J. Virol. 72:6291-6297.
    • (1998) J. Virol. , vol.72 , pp. 6291-6297
    • Lu, R.1    Yang, P.2    Padmakumar, S.3    Misra, V.4
  • 39
    • 0345803936 scopus 로고    scopus 로고
    • HCF-1 functions as a coactivator for the zinc finger protein Krox20
    • Luciano, R. L., and A. C. Wilson. 2003. HCF-1 functions as a coactivator for the zinc finger protein Krox20. J. Biol. Chem. 278:51116-51124.
    • (2003) J. Biol. Chem. , vol.278 , pp. 51116-51124
    • Luciano, R.L.1    Wilson, A.C.2
  • 43
    • 0037039309 scopus 로고    scopus 로고
    • A trithorax-group complex purified from Saccharomyces cerevisiae is required for methylation of histone H3
    • Nagy, P. L., J. Griesenbeck, R. D. Kornberg, and M. L. Cleary. 2002. A trithorax-group complex purified from Saccharomyces cerevisiae is required for methylation of histone H3. Proc. Natl. Acad. Sci. USA 99:90-94.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 90-94
    • Nagy, P.L.1    Griesenbeck, J.2    Kornberg, R.D.3    Cleary, M.L.4
  • 46
    • 0037427562 scopus 로고    scopus 로고
    • Menin interacting proteins as clues toward the understanding of multiple endocrine neoplasia type 1
    • Poisson, A., B. Zablewska, and P. Gaudray. 2003. Menin interacting proteins as clues toward the understanding of multiple endocrine neoplasia type 1, Cancer Lett. 189:1-10.
    • (2003) Cancer Lett. , vol.189 , pp. 1-10
    • Poisson, A.1    Zablewska, B.2    Gaudray, P.3
  • 47
    • 0037126594 scopus 로고    scopus 로고
    • The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4
    • Roguev, A., D. Schaft, A. Shevchenko, W. W. Pijnappel, M. Wilm, R. Aasland, and A. F. Stewart, 2001. The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4. EMBO J. 20:7137-7148.
    • (2001) EMBO J. , vol.20 , pp. 7137-7148
    • Roguev, A.1    Schaft, D.2    Shevchenko, A.3    Pijnappel, W.W.4    Wilm, M.5    Aasland, R.6    Stewart, A.F.7
  • 49
    • 0029064774 scopus 로고
    • Molecular cloning of a human protein that binds to the retinoblastoma protein and chromosomal mapping
    • Saijo, M., Y. Sakai, T. Kishino, N. Niikawa, Y. Matsuura, K. Morino, K. Tamai, and Y. Taya. 1995. Molecular cloning of a human protein that binds to the retinoblastoma protein and chromosomal mapping. Genomics 27:511-519.
    • (1995) Genomics , vol.27 , pp. 511-519
    • Saijo, M.1    Sakai, Y.2    Kishino, T.3    Niikawa, N.4    Matsuura, Y.5    Morino, K.6    Tamai, K.7    Taya, Y.8
  • 50
  • 51
    • 0028264508 scopus 로고
    • The bithorax complex is regulated by trithorax earlier during Drosophila embryogenesis than is the antennapedia complex, correlating with a bithorax-like expression pattern of distinct early trithorax transcripts
    • Sedkov, Y., S. Tillib, L. Mizrokhi, and A. Mazo. 1994. The bithorax complex is regulated by trithorax earlier during Drosophila embryogenesis than is the antennapedia complex, correlating with a bithorax-like expression pattern of distinct early trithorax transcripts. Development 120:1907-1917.
    • (1994) Development , vol.120 , pp. 1907-1917
    • Sedkov, Y.1    Tillib, S.2    Mizrokhi, L.3    Mazo, A.4
  • 52
    • 0031972784 scopus 로고    scopus 로고
    • The oncogenic capacity of HRX-ENL requires the transcriptional transactivation activity of ENL and the DNA binding motifs of HRX
    • Slany, R. K., C. Lavau, and M. L. Cleary. 1998. The oncogenic capacity of HRX-ENL requires the transcriptional transactivation activity of ENL and the DNA binding motifs of HRX. Mol. Cell. Biol. 18:122-129.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 122-129
    • Slany, R.K.1    Lavau, C.2    Cleary, M.L.3
  • 53
    • 1842579481 scopus 로고    scopus 로고
    • Leukemic transformation of hematopietic progenitors by MLL-GAS7 in the absence of Hoxa7 or Hoxa9
    • So, C. W., H. Karsunky, P. Wong, I. L. Weissman, and M. L. Cleary. 2004. Leukemic transformation of hematopietic progenitors by MLL-GAS7 in the absence of Hoxa7 or Hoxa9. Blood 103:3192-3199.
    • (2004) Blood , vol.103 , pp. 3192-3199
    • So, C.W.1    Karsunky, H.2    Wong, P.3    Weissman, I.L.4    Cleary, M.L.5
  • 54
    • 0042885909 scopus 로고    scopus 로고
    • Dimerization contributes to oncogenic activation of MLL chimeras in acute leukemias
    • So, C. W., M. Lin, P. M. Ayton, E. H. Chen, and M. L. Cleary. 2003. Dimerization contributes to oncogenic activation of MLL chimeras in acute leukemias. Cancer Cell 4:99-110.
    • (2003) Cancer Cell , vol.4 , pp. 99-110
    • So, C.W.1    Lin, M.2    Ayton, P.M.3    Chen, E.H.4    Cleary, M.L.5
  • 56
    • 0026454451 scopus 로고
    • Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias
    • Tkachuk, D. C., S. Kohler, and M. L. Cleary. 1992. Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias. Cell 71:691-700.
    • (1992) Cell , vol.71 , pp. 691-700
    • Tkachuk, D.C.1    Kohler, S.2    Cleary, M.L.3
  • 57
    • 0034917248 scopus 로고    scopus 로고
    • ASH2L: Alternative splicing and downregulation during induced megakaryocytic differentiation of multipotential leukemia cell lines
    • Wang, J., Y. Zhou, B. Yin, G. Du, X. Huang, G. Li, Y. Shen, J. Yuan, and B. Qiang. 2001. ASH2L: alternative splicing and downregulation during induced megakaryocytic differentiation of multipotential leukemia cell lines. J. Mol. Med. 79:399-405.
    • (2001) J. Mol. Med. , vol.79 , pp. 399-405
    • Wang, J.1    Zhou, Y.2    Yin, B.3    Du, G.4    Huang, X.5    Li, G.6    Shen, Y.7    Yuan, J.8    Qiang, B.9
  • 58
    • 0027328280 scopus 로고
    • The VP16 accessory protein HCF is a family of polypeptides processed from a large precursor protein
    • Wilson, A. C., K. LaMarco, M. G. Peterson, and W. Herr. 1993. The VP16 accessory protein HCF is a family of polypeptides processed from a large precursor protein. Cell 74:115-125.
    • (1993) Cell , vol.74 , pp. 115-125
    • Wilson, A.C.1    LaMarco, K.2    Peterson, M.G.3    Herr, W.4
  • 59
    • 0028860944 scopus 로고
    • The HCF repeat is an unusual proteolytic cleavage signal
    • Wilson, A. C., M. G. Peterson, and W. Herr. 1995. The HCF repeat is an unusual proteolytic cleavage signal. Genes Dev. 9:2445-2458.
    • (1995) Genes Dev. , vol.9 , pp. 2445-2458
    • Wilson, A.C.1    Peterson, M.G.2    Herr, W.3
  • 60
    • 0038434062 scopus 로고    scopus 로고
    • The herpes simplex virus VP16-induced complex: The makings of a regulatory switch
    • Wysocka, J., and W. Herr. 2003. The herpes simplex virus VP16-induced complex: the makings of a regulatory switch. Trends Biochem. Sci. 28:294-304.
    • (2003) Trends Biochem. Sci. , vol.28 , pp. 294-304
    • Wysocka, J.1    Herr, W.2
  • 61
    • 0037382574 scopus 로고    scopus 로고
    • Human Sin3 deacetylase and trithorax-related Setl/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1
    • Wysocka, J., M. P. Myers, C. D. Laherty, R. N. Eisenman, and W. Herr. 2003. Human Sin3 deacetylase and trithorax-related Setl/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1. Genes Dev. 17:896-911.
    • (2003) Genes Dev. , vol.17 , pp. 896-911
    • Wysocka, J.1    Myers, M.P.2    Laherty, C.D.3    Eisenman, R.N.4    Herr, W.5
  • 62
    • 0038492426 scopus 로고    scopus 로고
    • MLL repression domain interacts with histone deacetylases, the polycomb group proteins HPC2 and BMI-1, and the corepressor C-terminal-binding protein
    • Xia, Z. B., M. Anderson, M. O. Diaz, and N. J. Zeleznik-Le. 2003. MLL repression domain interacts with histone deacetylases, the polycomb group proteins HPC2 and BMI-1, and the corepressor C-terminal-binding protein. Proc. Natl. Acad. Sci. USA 100:8342-8347.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 8342-8347
    • Xia, Z.B.1    Anderson, M.2    Diaz, M.O.3    Zeleznik-Le, N.J.4
  • 64
    • 0037111567 scopus 로고    scopus 로고
    • Leukemia proto-oncoprotein MLL is proteolytically processed into 2 fragments with opposite transcriptional properties
    • Yokoyama, A., I. Kitabayashi, P. M. Ayton, M. L. Cleary, and M. Ohki, 2002. Leukemia proto-oncoprotein MLL is proteolytically processed into 2 fragments with opposite transcriptional properties. Blood 100:3710-3718.
    • (2002) Blood , vol.100 , pp. 3710-3718
    • Yokoyama, A.1    Kitabayashi, I.2    Ayton, P.M.3    Cleary, M.L.4    Ohki, M.5
  • 65
    • 0032168459 scopus 로고    scopus 로고
    • MLL, a mammalian trithorax-group gene, functions as a transcriptional maintenance factor in morphogenesis
    • Yu, B. D., R. D. Hanson, J. L. Hess, S. E. Horning, and S. J. Korsmeyer. 1998. MLL, a mammalian trithorax-group gene, functions as a transcriptional maintenance factor in morphogenesis. Proc. Natl. Acad. Sci. USA 95:10632-10636.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 10632-10636
    • Yu, B.D.1    Hanson, R.D.2    Hess, J.L.3    Horning, S.E.4    Korsmeyer, S.J.5
  • 66
    • 0028869112 scopus 로고
    • Altered Hox expression and segmental identity in Mll-mutant mice
    • Yu, B. D., J. L. Hess, S. E. Horning, G. A. Brown, and S. J. Korsmeyer. 1995. Altered Hox expression and segmental identity in Mll-mutant mice. Nature 378:505-508.
    • (1995) Nature , vol.378 , pp. 505-508
    • Yu, B.D.1    Hess, J.L.2    Horning, S.E.3    Brown, G.A.4    Korsmeyer, S.J.5
  • 68
    • 0037328737 scopus 로고    scopus 로고
    • Transcriptional activation is a key function encoded by MLL fusion partners
    • Zeisig, B. B., S. Schreiner, M. P. Garcia-Cuellar, and R. K. Slany. 2003. Transcriptional activation is a key function encoded by MLL fusion partners. Leukemia 17:359-365.
    • (2003) Leukemia , vol.17 , pp. 359-365
    • Zeisig, B.B.1    Schreiner, S.2    Garcia-Cuellar, M.P.3    Slany, R.K.4
  • 69
    • 0028091804 scopus 로고
    • 11q23 translocations split the "AT-hook" cruciform DNA-binding region and the transcriptional repression domain from the activation domain of the mixed-lineage leukemia (MLL) gene
    • Zeleznik-Le, N. J., A. M. Harden, and J. D. Rowley. 1994. 11q23 translocations split the "AT-hook" cruciform DNA-binding region and the transcriptional repression domain from the activation domain of the mixed-lineage leukemia (MLL) gene. Proc. Natl. Acad. Sci. USA 91:10610-10614.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 10610-10614
    • Zeleznik-Le, N.J.1    Harden, A.M.2    Rowley, J.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.