The tumor suppressor Wnt inhibitory factor 1 is frequently methylated in nasopharyngeal and esophageal carcinomas

Laboratory Investigation

Volumn 87, Issue 7, 2007, Pages 644-650

  Chan, Stephen L ^a   Cui, Yan ^a   Van Hasselt, Andrew ^b   Li, Hongyu ^a   Srivastava, Gopesh ^c   Jin, Hongchuan ^a   Ng, Ka M ^a   Wang, Yajun ^a   Lee, Kwan Y ^a   Tsao, George S W ^c   Zhong, Sheng ^d   Robertson, Keith D ^d   Rha, Sun Y ^e   Chan, Anthony T C ^a   Tao, Qian ^a,b,f  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^c UNIVERSITY OF HONG KONG   (Hong Kong)

^d UNIVERSITY OF FLORIDA   (United States)

^e Yonsei University College of Medicine   (South Korea)

^f JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

catenin; Esophageal carcinoma; Methylation; Nasopharyngeal carcinoma; Tumor suppressor gene; WIF1

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; PROTEIN P53; TUMOR MARKER; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; WNT INHIBITORY FACTOR 1;

ARTICLE; CANCER CELL CULTURE; COLONY FORMATION; CONTROLLED STUDY; DNA METHYLATION; EPIGENETICS; ESOPHAGUS CARCINOMA; GENE EXPRESSION; GENE FUNCTION; GENE INACTIVATION; GENE SEQUENCE; GENE SILENCING; GENOME ANALYSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; NASOPHARYNX CARCINOMA; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR GENE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; AZACITIDINE; CARCINOMA; CELL LINE; CELL LINE, TUMOR; CELL PROLIFERATION; DNA METHYLATION; DOWN-REGULATION; ESOPHAGEAL NEOPLASMS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; HUMANS; NASOPHARYNGEAL NEOPLASMS; PROMOTER REGIONS (GENETICS); REPRESSOR PROTEINS; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEINS; WNT1 PROTEIN;

EID: 34250310905     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.3700547     Document Type: Article

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