메뉴 건너뛰기




Volumn 50, Issue 6, 2012, Pages 2155-2170

Chemoprevention of liver cancer by plant polyphenols

Author keywords

Chemoprevention; Liver cancer; Plant polyphenols

Indexed keywords

ACACETIN; CAFFEIC ACID; CAFFEIC ACID PHENETHYL ESTER; CAPSAICIN; CARBOPLATIN; CASPASE; CAVEOLIN 1; CURCUMIN; CYCLIN DEPENDENT KINASE; DAIDZEIN; DOXORUBICIN; ELLAGIC ACID; EPIGALLOCATECHIN GALLATE; FLAVONOID; FLUOROURACIL; GENISTEIN; GLUTATHIONE; LUTEOLIN; MICRORNA; PACLITAXEL; PLANT POLYPHENOL; POLYPHENOL DERIVATIVE; PROTEIN P53; PROTOCATECHUIC ACID; QUERCETIN; REACTIVE OXYGEN METABOLITE; RESVERATROL; SILIBININ; SILYMARIN; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 84860332038     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2012.04.002     Document Type: Review
Times cited : (164)

References (199)
  • 2
    • 80053607424 scopus 로고    scopus 로고
    • Proanthocyanidins modulate MicroRNA expression in human HepG2 cells
    • Arola-Arnal A., Blade C. Proanthocyanidins modulate MicroRNA expression in human HepG2 cells. PLoS One 2011, 6:25982.
    • (2011) PLoS One , vol.6 , pp. 25982
    • Arola-Arnal, A.1    Blade, C.2
  • 4
    • 55849096218 scopus 로고    scopus 로고
    • A comparative proteomic analysis for capsaicin-induced apoptosis between human hepatocarcinoma (HepG2) and human neuroblastoma (SK-N-SH) cells
    • Baek Y.M., Hwang H.J., Kim S.W., Hwang H.S., Lee S.H., Kim J.A., Yun J.W. A comparative proteomic analysis for capsaicin-induced apoptosis between human hepatocarcinoma (HepG2) and human neuroblastoma (SK-N-SH) cells. Proteomics 2008, 8:4748-4767.
    • (2008) Proteomics , vol.8 , pp. 4748-4767
    • Baek, Y.M.1    Hwang, H.J.2    Kim, S.W.3    Hwang, H.S.4    Lee, S.H.5    Kim, J.A.6    Yun, J.W.7
  • 6
    • 62549154478 scopus 로고    scopus 로고
    • Resveratrol-mediated chemoprevention of diethylnitrosamine-initiated hepatocarcinogenesis: inhibition of cell proliferation and induction of apoptosis
    • Bishayee A., Dhir N. Resveratrol-mediated chemoprevention of diethylnitrosamine-initiated hepatocarcinogenesis: inhibition of cell proliferation and induction of apoptosis. Chem. Biol. Interact. 2009, 179:131-144.
    • (2009) Chem. Biol. Interact. , vol.179 , pp. 131-144
    • Bishayee, A.1    Dhir, N.2
  • 7
    • 77953229913 scopus 로고    scopus 로고
    • Resveratrol suppresses oxidative stress and inflammatory response in diethylnitrosamine-initiated rat hepatocarcinogenesis
    • Bishayee A., Barnes K.F., Bhatia D., Darvesh A.S., Carroll R.T. Resveratrol suppresses oxidative stress and inflammatory response in diethylnitrosamine-initiated rat hepatocarcinogenesis. Cancer Prev. Res. 2010, 3:753-763.
    • (2010) Cancer Prev. Res. , vol.3 , pp. 753-763
    • Bishayee, A.1    Barnes, K.F.2    Bhatia, D.3    Darvesh, A.S.4    Carroll, R.T.5
  • 8
    • 77953231047 scopus 로고    scopus 로고
    • Suppression of the inflammatory cascade is implicated in resveratrol chemoprevention of experimental hepatocarcinogenesis
    • Bishayee A., Waghray A., Barnes K.F., Mbimba T., Bhatia D., Chatterjee M., Darvesh A.S. Suppression of the inflammatory cascade is implicated in resveratrol chemoprevention of experimental hepatocarcinogenesis. Pharm. Res. 2010, 27:1080-1091.
    • (2010) Pharm. Res. , vol.27 , pp. 1080-1091
    • Bishayee, A.1    Waghray, A.2    Barnes, K.F.3    Mbimba, T.4    Bhatia, D.5    Chatterjee, M.6    Darvesh, A.S.7
  • 9
    • 74649083195 scopus 로고    scopus 로고
    • Resveratrol in the chemoprevention and treatment of hepatocellular carcinoma
    • Bishayee A., Politis T., Darvesh A.S. Resveratrol in the chemoprevention and treatment of hepatocellular carcinoma. Cancer Treat. Rev. 2010, 36:43-53.
    • (2010) Cancer Treat. Rev. , vol.36 , pp. 43-53
    • Bishayee, A.1    Politis, T.2    Darvesh, A.S.3
  • 10
    • 79954569214 scopus 로고    scopus 로고
    • The two faces of capsaicin
    • Bode A.M., Dong Z. The two faces of capsaicin. Cancer Res. 2011, 71(8):2809-2814.
    • (2011) Cancer Res. , vol.71 , Issue.8 , pp. 2809-2814
    • Bode, A.M.1    Dong, Z.2
  • 11
    • 59849105278 scopus 로고    scopus 로고
    • Effects of silymarin on hepatitis C virus and haem oxygenase-1 gene expression in human hepatoma cells
    • Bonifaz V., Shan Y., Lambrecht R.W., Donohue S.E., Moschenross D., Bonkovsky H.L. Effects of silymarin on hepatitis C virus and haem oxygenase-1 gene expression in human hepatoma cells. Liver Int. 2009, 29:366-373.
    • (2009) Liver Int. , vol.29 , pp. 366-373
    • Bonifaz, V.1    Shan, Y.2    Lambrecht, R.W.3    Donohue, S.E.4    Moschenross, D.5    Bonkovsky, H.L.6
  • 15
    • 84856728144 scopus 로고    scopus 로고
    • Green tea polyphenol epigallocatechin-3-gallate shows therapeutic antioxidative effects in a murine model of colitis
    • Brückner M., Westphal S., Domschke W., Kucharzik T., Lügering A. Green tea polyphenol epigallocatechin-3-gallate shows therapeutic antioxidative effects in a murine model of colitis. J. Crohns Colitis 2012, 6(2):226-235.
    • (2012) J. Crohns Colitis , vol.6 , Issue.2 , pp. 226-235
    • Brückner, M.1    Westphal, S.2    Domschke, W.3    Kucharzik, T.4    Lügering, A.5
  • 17
    • 0035061788 scopus 로고    scopus 로고
    • Interferon and prevention of hepatocellular carcinoma in viral cirrhosis: an evidence-based approach
    • Cammà C., Giunta M., Andreone P., Craxì A. Interferon and prevention of hepatocellular carcinoma in viral cirrhosis: an evidence-based approach. J. Hepatol. 2001, 34:593-602.
    • (2001) J. Hepatol. , vol.34 , pp. 593-602
    • Cammà, C.1    Giunta, M.2    Andreone, P.3    Craxì, A.4
  • 18
    • 70450123699 scopus 로고    scopus 로고
    • Resveratrol: a natural polyphenol with multiple chemopreventive properties
    • Brisdelli F., D'Andrea G., Bozzi A. Resveratrol: a natural polyphenol with multiple chemopreventive properties. Curr. Drug Metab. 2009, 10:530-546.
    • (2009) Curr. Drug Metab. , vol.10 , pp. 530-546
    • Brisdelli, F.1    D'Andrea, G.2    Bozzi, A.3
  • 19
    • 76449120603 scopus 로고    scopus 로고
    • Antiviral activity of resveratrol
    • Campagna M., Rivas C. Antiviral activity of resveratrol. Biochem. Soc. Trans. 2010, 38:50-53.
    • (2010) Biochem. Soc. Trans. , vol.38 , pp. 50-53
    • Campagna, M.1    Rivas, C.2
  • 21
    • 33744805811 scopus 로고    scopus 로고
    • Mitochondrial and nuclear DNA damage induced by curcumin in human hepatoma G2 cells
    • Cao J., Jia L., Zhou H.M., Liu Y., Zhong L.F. Mitochondrial and nuclear DNA damage induced by curcumin in human hepatoma G2 cells. Toxicol. Sci. 2006, 91:476-483.
    • (2006) Toxicol. Sci. , vol.91 , pp. 476-483
    • Cao, J.1    Jia, L.2    Zhou, H.M.3    Liu, Y.4    Zhong, L.F.5
  • 22
    • 34547657453 scopus 로고    scopus 로고
    • Curcumin induces apoptosis through mitochondrial hyperpolarization and mtDNA damage in human hepatoma G2 cells
    • Cao J., Liu Y., Jia L., Zhou H.M., Kong Y., Yang G., Jiang L.P., Li Q.J., Zhong L.F. Curcumin induces apoptosis through mitochondrial hyperpolarization and mtDNA damage in human hepatoma G2 cells. Free Radic. Biol. Med. 2007, 43:968-975.
    • (2007) Free Radic. Biol. Med. , vol.43 , pp. 968-975
    • Cao, J.1    Liu, Y.2    Jia, L.3    Zhou, H.M.4    Kong, Y.5    Yang, G.6    Jiang, L.P.7    Li, Q.J.8    Zhong, L.F.9
  • 23
    • 85033057936 scopus 로고    scopus 로고
    • Chemopreventive effects of green and black tea on pulmonary and hepatic carcinogenesis
    • Cao J., Xu Y., Chen J., Klaunig J.E. Chemopreventive effects of green and black tea on pulmonary and hepatic carcinogenesis. Fundam. Appl. Toxicol. 1996, 29(2):244-250.
    • (1996) Fundam. Appl. Toxicol. , vol.29 , Issue.2 , pp. 244-250
    • Cao, J.1    Xu, Y.2    Chen, J.3    Klaunig, J.E.4
  • 26
    • 0030965103 scopus 로고    scopus 로고
    • Universal hepatitis B vaccination in Taiwan and the incidence of hepatocellular carcinoma in children. Taiwan Childhood Hepatoma Study Group
    • Chang M.H., Chen C.J., Lai M.S., Hsu H.M., Wu T.C., Kong M.S., Liang D.C., Shau W.Y., Chen D.S. Universal hepatitis B vaccination in Taiwan and the incidence of hepatocellular carcinoma in children. Taiwan Childhood Hepatoma Study Group. N. Engl. J. Med. 1997, 336:1855-1859.
    • (1997) N. Engl. J. Med. , vol.336 , pp. 1855-1859
    • Chang, M.H.1    Chen, C.J.2    Lai, M.S.3    Hsu, H.M.4    Wu, T.C.5    Kong, M.S.6    Liang, D.C.7    Shau, W.Y.8    Chen, D.S.9
  • 27
    • 13444282282 scopus 로고    scopus 로고
    • Increase of Bax/Bcl-XL ratio and arrest of cell cycle by luteolin in immortalized human hepatoma cell line
    • Chang J., Hsu Y., Kuo P., Kuo Y., Chiang L., Lin C. Increase of Bax/Bcl-XL ratio and arrest of cell cycle by luteolin in immortalized human hepatoma cell line. Life Sci. 2005, 76:1883-1893.
    • (2005) Life Sci. , vol.76 , pp. 1883-1893
    • Chang, J.1    Hsu, Y.2    Kuo, P.3    Kuo, Y.4    Chiang, L.5    Lin, C.6
  • 28
    • 33750892350 scopus 로고    scopus 로고
    • Reactive oxygen species production is involved in quercetin-induced apoptosis in human hepatoma cells
    • Chang Y.F., Chi C.W., Wang J.J. Reactive oxygen species production is involved in quercetin-induced apoptosis in human hepatoma cells. Nutr. Cancer 2006, 55:201-209.
    • (2006) Nutr. Cancer , vol.55 , pp. 201-209
    • Chang, Y.F.1    Chi, C.W.2    Wang, J.J.3
  • 29
    • 0033862041 scopus 로고    scopus 로고
    • Chromosomal changes and clonality relationship between primary and recurrent hepatocellular carcinoma
    • Chen Y.J., Yeh S.H., Chen J.T., Wu C.C., Hsu M.T., Tsai S.F., Chen P.J., Lin C.H. Chromosomal changes and clonality relationship between primary and recurrent hepatocellular carcinoma. Gastroenterology 2000, 119:431-440.
    • (2000) Gastroenterology , vol.119 , pp. 431-440
    • Chen, Y.J.1    Yeh, S.H.2    Chen, J.T.3    Wu, C.C.4    Hsu, M.T.5    Tsai, S.F.6    Chen, P.J.7    Lin, C.H.8
  • 30
    • 56049114437 scopus 로고    scopus 로고
    • Genistein induction of human sulfotransferases in HepG2 and Caco-2 cells
    • Chen Y., Huang C., Zhou T., Chen G. Genistein induction of human sulfotransferases in HepG2 and Caco-2 cells. Basic Clin. Pharmacol. Toxicol. 2008, 103:553-559.
    • (2008) Basic Clin. Pharmacol. Toxicol. , vol.103 , pp. 553-559
    • Chen, Y.1    Huang, C.2    Zhou, T.3    Chen, G.4
  • 32
    • 77957876440 scopus 로고    scopus 로고
    • Curcumin inhibits the proliferation of human hepatocellular carcinoma J5 cells by inducing endoplasmic reticulum stress and mitochondrial dysfunction
    • Cheng C.Y., Lin Y.H., Su C.C. Curcumin inhibits the proliferation of human hepatocellular carcinoma J5 cells by inducing endoplasmic reticulum stress and mitochondrial dysfunction. Int. J. Mol. Med. 2010, 26:673-678.
    • (2010) Int. J. Mol. Med. , vol.26 , pp. 673-678
    • Cheng, C.Y.1    Lin, Y.H.2    Su, C.C.3
  • 34
    • 77951668726 scopus 로고    scopus 로고
    • Caveolae, caveolins, and cavins: complex control of cellular signalling and inflammation
    • Chidlow J.H., Sessa W.C. Caveolae, caveolins, and cavins: complex control of cellular signalling and inflammation. Cardiovasc. Res. 2010, 86:219-225.
    • (2010) Cardiovasc. Res. , vol.86 , pp. 219-225
    • Chidlow, J.H.1    Sessa, W.C.2
  • 35
    • 34247134655 scopus 로고    scopus 로고
    • Preliminary studies on induction of apoptosis by genistein on HepG2 cell line
    • Chodon D., Ramamurty N., Sakthisekaran D. Preliminary studies on induction of apoptosis by genistein on HepG2 cell line. Toxicol. In Vitro 2007, 21:887-891.
    • (2007) Toxicol. In Vitro , vol.21 , pp. 887-891
    • Chodon, D.1    Ramamurty, N.2    Sakthisekaran, D.3
  • 39
    • 7744221596 scopus 로고    scopus 로고
    • Novel and therapeutic effect of caffeic acid and caffeic acid phenyl ester on hepatocarcinoma cells: complete regression of hepatoma growth and metastasis by dual mechanism
    • Chung T.W., Moon S.K., Chang Y.C., Ko J.H., Lee Y.C., Cho G., Kim S.H., Kim J.G., Kim C.H. Novel and therapeutic effect of caffeic acid and caffeic acid phenyl ester on hepatocarcinoma cells: complete regression of hepatoma growth and metastasis by dual mechanism. FASEB J. 2004, 18:1670-1681.
    • (2004) FASEB J. , vol.18 , pp. 1670-1681
    • Chung, T.W.1    Moon, S.K.2    Chang, Y.C.3    Ko, J.H.4    Lee, Y.C.5    Cho, G.6    Kim, S.H.7    Kim, J.G.8    Kim, C.H.9
  • 40
    • 67651171486 scopus 로고    scopus 로고
    • Effects and mechanisms of silibinin on human hepatocellular carcinoma xenografts in nude mice
    • Cui W., Gu F., Hu K.Q. Effects and mechanisms of silibinin on human hepatocellular carcinoma xenografts in nude mice. World J. Gastroenterol. 2009, 15:1943-1950.
    • (2009) World J. Gastroenterol. , vol.15 , pp. 1943-1950
    • Cui, W.1    Gu, F.2    Hu, K.Q.3
  • 41
    • 34547441997 scopus 로고    scopus 로고
    • Radiofrequency ablation of primary and metastatic liver tumors
    • Curley S.A., Izzo F. Radiofrequency ablation of primary and metastatic liver tumors. Surg. Technol. Int. 2002, 10:99-106.
    • (2002) Surg. Technol. Int. , vol.10 , pp. 99-106
    • Curley, S.A.1    Izzo, F.2
  • 42
    • 78649630983 scopus 로고    scopus 로고
    • Resveratrol and cardiovascular health
    • Das M., Das D.K. Resveratrol and cardiovascular health. Mol. Aspects Med. 2010, 31:503-512.
    • (2010) Mol. Aspects Med. , vol.31 , pp. 503-512
    • Das, M.1    Das, D.K.2
  • 44
    • 1242274347 scopus 로고    scopus 로고
    • Effects of a genistein-rich extract on PSA levels in men with a history of prostate cancer
    • deVere White R.W., Hackman R.M., Soares S.E., Beckett L.A., Li Y., Sun B. Effects of a genistein-rich extract on PSA levels in men with a history of prostate cancer. Urology 2004, 63:259-263.
    • (2004) Urology , vol.63 , pp. 259-263
    • deVere White, R.W.1    Hackman, R.M.2    Soares, S.E.3    Beckett, L.A.4    Li, Y.5    Sun, B.6
  • 45
    • 0034219435 scopus 로고    scopus 로고
    • Inhibitory effect of resveratrol on the proliferation of human and rat hepatic derived cell lines
    • Delmas D., Jannin B., Cherkaoui Malki M., Latruffe N. Inhibitory effect of resveratrol on the proliferation of human and rat hepatic derived cell lines. Oncol. Rep. 2000, 7:847-852.
    • (2000) Oncol. Rep. , vol.7 , pp. 847-852
    • Delmas, D.1    Jannin, B.2    Cherkaoui Malki, M.3    Latruffe, N.4
  • 49
    • 0035140369 scopus 로고    scopus 로고
    • Epidemiology of hepatocellular carcinoma
    • El-Serag H.B. Epidemiology of hepatocellular carcinoma. Clin. Liver Dis. 2001, 5:87-107.
    • (2001) Clin. Liver Dis. , vol.5 , pp. 87-107
    • El-Serag, H.B.1
  • 50
    • 0842321807 scopus 로고    scopus 로고
    • Diabetes increases the risk of chronic liver disease and hepatocellular carcinoma
    • El-Serag H.B., Tran T., Everhart J.E. Diabetes increases the risk of chronic liver disease and hepatocellular carcinoma. Gastroenterology 2004, 126:460-468.
    • (2004) Gastroenterology , vol.126 , pp. 460-468
    • El-Serag, H.B.1    Tran, T.2    Everhart, J.E.3
  • 51
    • 59549107896 scopus 로고    scopus 로고
    • Silibinin inhibits hypoxia-inducible factor-1alpha and mTOR/p70S6K/4E-BP1 signalling pathway in human cervical and hepatoma cancer cells: implications for anticancer therapy
    • García-Maceira P., Mateo J. Silibinin inhibits hypoxia-inducible factor-1alpha and mTOR/p70S6K/4E-BP1 signalling pathway in human cervical and hepatoma cancer cells: implications for anticancer therapy. Oncogene 2009, 28:313-324.
    • (2009) Oncogene , vol.28 , pp. 313-324
    • García-Maceira, P.1    Mateo, J.2
  • 53
    • 14044264191 scopus 로고    scopus 로고
    • Tert-Butylhydroquinone is a novel aryl hydrocarbon receptor ligand
    • Gharavi N., El-Kadi A.O. Tert-Butylhydroquinone is a novel aryl hydrocarbon receptor ligand. Drug Metab. Dispos. 2005, 33:365-372.
    • (2005) Drug Metab. Dispos. , vol.33 , pp. 365-372
    • Gharavi, N.1    El-Kadi, A.O.2
  • 55
    • 48649099511 scopus 로고    scopus 로고
    • Time-course regulation of quercetin on cell survival/proliferation pathways in human hepatoma cells
    • Granado-Serrano A.B., Angeles Martin M., Bravo L., Goya L., Ramos S. Time-course regulation of quercetin on cell survival/proliferation pathways in human hepatoma cells. Mol. Nutr. Food Res. 2008, 52:457-464.
    • (2008) Mol. Nutr. Food Res. , vol.52 , pp. 457-464
    • Granado-Serrano, A.B.1    Angeles Martin, M.2    Bravo, L.3    Goya, L.4    Ramos, S.5
  • 56
    • 77951112788 scopus 로고    scopus 로고
    • Quercetin modulates NF-kappa B and AP-1/JNK pathways to induce cell death in human hepatoma cells
    • Granado-Serrano A.B., Martin M.A., Bravo L., Goya L., Ramos S. Quercetin modulates NF-kappa B and AP-1/JNK pathways to induce cell death in human hepatoma cells. Nutr. Cancer 2010, 62:390-401.
    • (2010) Nutr. Cancer , vol.62 , pp. 390-401
    • Granado-Serrano, A.B.1    Martin, M.A.2    Bravo, L.3    Goya, L.4    Ramos, S.5
  • 57
    • 31344441221 scopus 로고    scopus 로고
    • Genistein inhibits invasive potential of human hepatocellular carcinoma by altering cell cycle, apoptosis, and angiogenesis
    • Gu Y., Zhu C.F., Iwamoto H., Chen J.S. Genistein inhibits invasive potential of human hepatocellular carcinoma by altering cell cycle, apoptosis, and angiogenesis. World J. Gastroenterol. 2005, 11:6512-6517.
    • (2005) World J. Gastroenterol. , vol.11 , pp. 6512-6517
    • Gu, Y.1    Zhu, C.F.2    Iwamoto, H.3    Chen, J.S.4
  • 58
    • 73949149188 scopus 로고    scopus 로고
    • Inhibitory effects of genistein on metastasis of human hepatocellular carcinoma
    • Gu Y., Zhu C.F., Dai Y.L., Zhong Q., Sun B. Inhibitory effects of genistein on metastasis of human hepatocellular carcinoma. World J. Gastroenterol. 2009, 15:4952-4957.
    • (2009) World J. Gastroenterol. , vol.15 , pp. 4952-4957
    • Gu, Y.1    Zhu, C.F.2    Dai, Y.L.3    Zhong, Q.4    Sun, B.5
  • 59
    • 0030434738 scopus 로고    scopus 로고
    • Inhibitory effects of phenolic compounds on development of naturally occurring preneoplastic hepatocytic foci in long-term feeding studies using male F344 rats
    • Hagiwara A., Kokubo Y., Takesada Y., Tanaka H., Tamano S., Hirose M., Shirai T., Ito N. Inhibitory effects of phenolic compounds on development of naturally occurring preneoplastic hepatocytic foci in long-term feeding studies using male F344 rats. Teratog. Carcinog. Mutagen. 1996, 16:317-325.
    • (1996) Teratog. Carcinog. Mutagen. , vol.16 , pp. 317-325
    • Hagiwara, A.1    Kokubo, Y.2    Takesada, Y.3    Tanaka, H.4    Tamano, S.5    Hirose, M.6    Shirai, T.7    Ito, N.8
  • 60
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • Hanahan D., Weinberg R.A. Hallmarks of cancer: the next generation. Cell 2011, 144:646-674.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 61
    • 1042275543 scopus 로고    scopus 로고
    • Acacetin inhibits the proliferation of Hep G2 by blocking cell cycle progression and inducing apoptosis
    • Hsu Y.L., Kuo P.L., Lin C.C. Acacetin inhibits the proliferation of Hep G2 by blocking cell cycle progression and inducing apoptosis. Biochem. Pharmacol. 2004, 67:823-829.
    • (2004) Biochem. Pharmacol. , vol.67 , pp. 823-829
    • Hsu, Y.L.1    Kuo, P.L.2    Lin, C.C.3
  • 62
    • 84863877443 scopus 로고    scopus 로고
    • Sorafenib and radiation therapy for the treatment of advanced hepatocellular carcinoma
    • [Epub ahead of print].
    • Horgan, A.M., Dawson, L.A., Swaminath, A., Knox, J.J., 2010. Sorafenib and radiation therapy for the treatment of advanced hepatocellular carcinoma. J. Gastrointest. Cancer. [Epub ahead of print].
    • (2010) J. Gastrointest. Cancer.
    • Horgan, A.M.1    Dawson, L.A.2    Swaminath, A.3    Knox, J.J.4
  • 64
    • 0029616654 scopus 로고
    • Inhibitory effects of 1-O-hexyl-2,3,5-trimethylhydroquinone (HTHQ), green tea catechins and other antioxidants on 2-amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole (Glu-P-1)-induced rat hepatocarcinogenesis and dose-dependent inhibition by HTHQ of lesion induction by Glu-P-1 or 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx)
    • Hirose M., Hasegawa R., Kimura J., Akagi K., Yoshida Y., Tanaka H., Miki T., Satoh T., Wakabayashi K., Ito N., et al. Inhibitory effects of 1-O-hexyl-2,3,5-trimethylhydroquinone (HTHQ), green tea catechins and other antioxidants on 2-amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole (Glu-P-1)-induced rat hepatocarcinogenesis and dose-dependent inhibition by HTHQ of lesion induction by Glu-P-1 or 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx). Carcinogenesis 1995, 16(12):3049-3055.
    • (1995) Carcinogenesis , vol.16 , Issue.12 , pp. 3049-3055
    • Hirose, M.1    Hasegawa, R.2    Kimura, J.3    Akagi, K.4    Yoshida, Y.5    Tanaka, H.6    Miki, T.7    Satoh, T.8    Wakabayashi, K.9    Ito, N.10
  • 65
    • 57849145212 scopus 로고    scopus 로고
    • Effects of curcumin on N-bis(2-hydroxypropyl) nitrosamine (DHPN)-induced lung and liver tumorigenesis in BALB/c mice in vivo
    • Huang A.C., Lin S.Y., Su C.C., Lin S.S., Ho C.C., Hsia T.C., Chiu T.H., Yu C.S., Ip S.W., Lin T.P., Chung J.G. Effects of curcumin on N-bis(2-hydroxypropyl) nitrosamine (DHPN)-induced lung and liver tumorigenesis in BALB/c mice in vivo. In vivo 2008, 22:781-785.
    • (2008) In vivo , vol.22 , pp. 781-785
    • Huang, A.C.1    Lin, S.Y.2    Su, C.C.3    Lin, S.S.4    Ho, C.C.5    Hsia, T.C.6    Chiu, T.H.7    Yu, C.S.8    Ip, S.W.9    Lin, T.P.10    Chung, J.G.11
  • 67
    • 0026095001 scopus 로고
    • Effect of repeated transcatheter arterial embolization on the survival time in patients with hepatocellular carcinoma. An analysis by the Cox proportional hazard model
    • Ikeda K., Kumada H., Saitoh S., Arase Y., Chayama K. Effect of repeated transcatheter arterial embolization on the survival time in patients with hepatocellular carcinoma. An analysis by the Cox proportional hazard model. Cancer 1991, 68:2150-2154.
    • (1991) Cancer , vol.68 , pp. 2150-2154
    • Ikeda, K.1    Kumada, H.2    Saitoh, S.3    Arase, Y.4    Chayama, K.5
  • 68
    • 0345074085 scopus 로고    scopus 로고
    • Dietary supplementation of curcumin enhances antioxidant and phase II metabolizing enzymes in ddY male mice: possible role in protection against chemical carcinogenesis and toxicity
    • Iqbal M., Sharma S.D., Okazaki Y., Fujisawa M., Okada S. Dietary supplementation of curcumin enhances antioxidant and phase II metabolizing enzymes in ddY male mice: possible role in protection against chemical carcinogenesis and toxicity. Pharmacol. Toxicol. 2003, 92:33-38.
    • (2003) Pharmacol. Toxicol. , vol.92 , pp. 33-38
    • Iqbal, M.1    Sharma, S.D.2    Okazaki, Y.3    Fujisawa, M.4    Okada, S.5
  • 69
    • 0842304283 scopus 로고    scopus 로고
    • Induction of apoptosis in leukemic cells by homovanillic acid derivative, capsaicin, through oxidative stress: implication of phosphorylation of p53 at Ser-15 residue by reactive oxygen species
    • Ito K., Nakazato T., Yamato K., Miyakawa Y., Yamada T., Hozumi N., Segawa K., Ikeda Y., Kizaki M. Induction of apoptosis in leukemic cells by homovanillic acid derivative, capsaicin, through oxidative stress: implication of phosphorylation of p53 at Ser-15 residue by reactive oxygen species. Cancer Res. 2004, 64:1071-1078.
    • (2004) Cancer Res. , vol.64 , pp. 1071-1078
    • Ito, K.1    Nakazato, T.2    Yamato, K.3    Miyakawa, Y.4    Yamada, T.5    Hozumi, N.6    Segawa, K.7    Ikeda, Y.8    Kizaki, M.9
  • 70
    • 0037041904 scopus 로고    scopus 로고
    • Phytoalexins from the Vitaceae: biosynthesis, phytoalexin gene expression in transgenic plants, antifungal activity, and metabolism
    • Jeandet P., Douillet-Breuil A.C., Bessis R., Debord S., Sbaghi M., Adrian M. Phytoalexins from the Vitaceae: biosynthesis, phytoalexin gene expression in transgenic plants, antifungal activity, and metabolism. J. Agric. Food Chem. 2002, 50:2731-2741.
    • (2002) J. Agric. Food Chem. , vol.50 , pp. 2731-2741
    • Jeandet, P.1    Douillet-Breuil, A.C.2    Bessis, R.3    Debord, S.4    Sbaghi, M.5    Adrian, M.6
  • 71
    • 0029788852 scopus 로고    scopus 로고
    • Differential regulation of p53, c-Myc, Bcl-2 and Bax protein expression during apoptosis induced by widely divergent stimuli in human hepatoblastoma cells
    • Jiang M.C., Yang-Yen H.F., Lin J.K., Yen J.J. Differential regulation of p53, c-Myc, Bcl-2 and Bax protein expression during apoptosis induced by widely divergent stimuli in human hepatoblastoma cells. Oncogene 1996, 13:609-616.
    • (1996) Oncogene , vol.13 , pp. 609-616
    • Jiang, M.C.1    Yang-Yen, H.F.2    Lin, J.K.3    Yen, J.J.4
  • 72
    • 27744466146 scopus 로고    scopus 로고
    • Caffeic acid phenyl ester in propolis is a strong inhibitor of matrix metalloproteinase-9 and invasion inhibitor: isolation and identification
    • Jin U.H., Chung T.W., Kang S.K., Suh S.J., Kim J.K., Chung K.H., Gu Y.H., Suzuki I., Kim C.H. Caffeic acid phenyl ester in propolis is a strong inhibitor of matrix metalloproteinase-9 and invasion inhibitor: isolation and identification. Clin. Chim. Acta 2005, 362:57-64.
    • (2005) Clin. Chim. Acta , vol.362 , pp. 57-64
    • Jin, U.H.1    Chung, T.W.2    Kang, S.K.3    Suh, S.J.4    Kim, J.K.5    Chung, K.H.6    Gu, Y.H.7    Suzuki, I.8    Kim, C.H.9
  • 73
    • 67349246450 scopus 로고    scopus 로고
    • Genistein enhances TRAIL-induced apoptosis through inhibition of p38 MAPK signaling in human hepatocellular carcinoma Hep3B cells
    • Jin C.Y., Park C., Kim G.Y., Lee S.J., Kim W.J., Choi Y.H. Genistein enhances TRAIL-induced apoptosis through inhibition of p38 MAPK signaling in human hepatocellular carcinoma Hep3B cells. Chem. Biol. Interact. 2009, 180:143-150.
    • (2009) Chem. Biol. Interact. , vol.180 , pp. 143-150
    • Jin, C.Y.1    Park, C.2    Kim, G.Y.3    Lee, S.J.4    Kim, W.J.5    Choi, Y.H.6
  • 74
    • 70349332934 scopus 로고    scopus 로고
    • Genistein sensitizes human hepatocellular carcinoma cells to TRAIL-mediated apoptosis by enhancing Bid cleavage
    • Jin C.Y., Park C., Moon S.K., Kim G.Y., Kwon T.K., Lee S.J., Kim W.J., Choi Y.H. Genistein sensitizes human hepatocellular carcinoma cells to TRAIL-mediated apoptosis by enhancing Bid cleavage. Anticancer Drugs 2009, 20:713-722.
    • (2009) Anticancer Drugs , vol.20 , pp. 713-722
    • Jin, C.Y.1    Park, C.2    Moon, S.K.3    Kim, G.Y.4    Kwon, T.K.5    Lee, S.J.6    Kim, W.J.7    Choi, Y.H.8
  • 75
    • 35848954977 scopus 로고    scopus 로고
    • Capsaicin induces heme oxygenase-1 expression in HepG2 cells via activation of PI3K-Nrf2 signaling: NAD(P)H:quinone oxidoreductase as a potential target
    • Joung E.J., Li M.H., Lee H.G., Somparn N., Jung Y.S., Na H.K., Kim S.H., Cha Y.N., Surh Y.J. Capsaicin induces heme oxygenase-1 expression in HepG2 cells via activation of PI3K-Nrf2 signaling: NAD(P)H:quinone oxidoreductase as a potential target. Antioxid. Redox Signal. 2007, 9:2087-2098.
    • (2007) Antioxid. Redox Signal. , vol.9 , pp. 2087-2098
    • Joung, E.J.1    Li, M.H.2    Lee, H.G.3    Somparn, N.4    Jung, Y.S.5    Na, H.K.6    Kim, S.H.7    Cha, Y.N.8    Surh, Y.J.9
  • 76
    • 0038352037 scopus 로고    scopus 로고
    • Involvement of NF-kappaB in the regulation of S100A6 gene expression in human hepatoblastoma cell line HepG2
    • Joo J.H., Kim J.W., Lee Y., Yoon S.Y., Kim J.H., Paik S.G., Choe I.S. Involvement of NF-kappaB in the regulation of S100A6 gene expression in human hepatoblastoma cell line HepG2. Biochem. Biophys. Res. Commun. 2003, 307:274-280.
    • (2003) Biochem. Biophys. Res. Commun. , vol.307 , pp. 274-280
    • Joo, J.H.1    Kim, J.W.2    Lee, Y.3    Yoon, S.Y.4    Kim, J.H.5    Paik, S.G.6    Choe, I.S.7
  • 77
    • 0035953849 scopus 로고    scopus 로고
    • Capsaicin-induced apoptosis in SK-Hep-1 hepatocarcinoma cells involves Bcl-2 downregulation and caspase-3 activation
    • Jung M.Y., Kang H.J., Moon A. Capsaicin-induced apoptosis in SK-Hep-1 hepatocarcinoma cells involves Bcl-2 downregulation and caspase-3 activation. Cancer Lett. 2001, 165:139-145.
    • (2001) Cancer Lett. , vol.165 , pp. 139-145
    • Jung, M.Y.1    Kang, H.J.2    Moon, A.3
  • 78
    • 35348879054 scopus 로고    scopus 로고
    • Silymarin and epithelial cancer chemoprevention: how close we are to bedside?
    • Kaur M., Agarwal R. Silymarin and epithelial cancer chemoprevention: how close we are to bedside?. Toxicol. Appl. Pharmacol. 2007, 224(3):350-359.
    • (2007) Toxicol. Appl. Pharmacol. , vol.224 , Issue.3 , pp. 350-359
    • Kaur, M.1    Agarwal, R.2
  • 81
    • 67649363667 scopus 로고    scopus 로고
    • Green tea polyphenol epigallocatechin-3-gallate inhibits thrombin-induced hepatocellular carcinoma cell invasion and p42/p44-MAPKinase activation
    • Kaufmann R., Henklein P., Henklein P., Settmacher U. Green tea polyphenol epigallocatechin-3-gallate inhibits thrombin-induced hepatocellular carcinoma cell invasion and p42/p44-MAPKinase activation. Oncol. Rep. 2009, 21:1261-1267.
    • (2009) Oncol. Rep. , vol.21 , pp. 1261-1267
    • Kaufmann, R.1    Henklein, P.2    Henklein, P.3    Settmacher, U.4
  • 82
    • 1642544666 scopus 로고    scopus 로고
    • Resveratrol inhibits N-nitrosodiethylamine-induced ornithine decarboxylase and cyclooxygenase in mice
    • Khanduja K.L., Bhardwaj A., Kaushik G. Resveratrol inhibits N-nitrosodiethylamine-induced ornithine decarboxylase and cyclooxygenase in mice. J. Nutr. Sci. Vitaminol. 2004, 50:61-65.
    • (2004) J. Nutr. Sci. Vitaminol. , vol.50 , pp. 61-65
    • Khanduja, K.L.1    Bhardwaj, A.2    Kaushik, G.3
  • 83
    • 20344400650 scopus 로고    scopus 로고
    • 2+ release pathway mediates the capsaicin-induced apoptosis in HepG2 human hepatoma cells
    • 2+ release pathway mediates the capsaicin-induced apoptosis in HepG2 human hepatoma cells. Arch. Pharm. Res. 2005, 28:73-80.
    • (2005) Arch. Pharm. Res. , vol.28 , pp. 73-80
    • Kim, J.A.1    Kang, Y.S.2    Lee, Y.S.3
  • 84
    • 57349169369 scopus 로고    scopus 로고
    • Quercetin sensitizes human hepatoma cells to TRAIL-induced apoptosis via Sp1-mediated DR5 up-regulation and proteasome-mediated c-FLIPS down-regulation
    • Kim J.Y., Kim E.H., Park S.S., Lim J.H., Kwon T.K., Choi K.S. Quercetin sensitizes human hepatoma cells to TRAIL-induced apoptosis via Sp1-mediated DR5 up-regulation and proteasome-mediated c-FLIPS down-regulation. J. Cell Biochem. 2008, 105:1386-1398.
    • (2008) J. Cell Biochem. , vol.105 , pp. 1386-1398
    • Kim, J.Y.1    Kim, E.H.2    Park, S.S.3    Lim, J.H.4    Kwon, T.K.5    Choi, K.S.6
  • 85
    • 17844365030 scopus 로고    scopus 로고
    • Chemopreventive properties of trans-resveratrol against the cytotoxicity of chloroacetanilide herbicides in vitro
    • Kocsis Z., Marcsek Z.L., Jakab M.G., Szende B., Tompa A. Chemopreventive properties of trans-resveratrol against the cytotoxicity of chloroacetanilide herbicides in vitro. Int. J. Hyg. Environ. Health 2005, 208:211-218.
    • (2005) Int. J. Hyg. Environ. Health , vol.208 , pp. 211-218
    • Kocsis, Z.1    Marcsek, Z.L.2    Jakab, M.G.3    Szende, B.4    Tompa, A.5
  • 86
    • 70450182123 scopus 로고    scopus 로고
    • Plant polyphenols and tumors: from mechanisms to therapies, prevention, and protection against toxicity of anti-cancer treatments
    • Korkina L.G., De Luca C., Kostyuk V.A., Pastore S. Plant polyphenols and tumors: from mechanisms to therapies, prevention, and protection against toxicity of anti-cancer treatments. Curr. Med. Chem. 2009, 16:3943-3965.
    • (2009) Curr. Med. Chem. , vol.16 , pp. 3943-3965
    • Korkina, L.G.1    De Luca, C.2    Kostyuk, V.A.3    Pastore, S.4
  • 87
    • 0035954245 scopus 로고    scopus 로고
    • Resveratrol suppresses hepatoma cell invasion independently of its anti-proliferative action
    • Kozuki Y., Miura Y., Yagasaki K. Resveratrol suppresses hepatoma cell invasion independently of its anti-proliferative action. Cancer Lett. 2001, 167:151-156.
    • (2001) Cancer Lett. , vol.167 , pp. 151-156
    • Kozuki, Y.1    Miura, Y.2    Yagasaki, K.3
  • 88
    • 0037159575 scopus 로고    scopus 로고
    • Resveratrol- induced apoptosis is mediated by p53-dependent pathway in Hep G2 cells
    • Kuo P.L., Chiang L.C., Lin C.C. Resveratrol- induced apoptosis is mediated by p53-dependent pathway in Hep G2 cells. Life Sci. 2002, 72:23-34.
    • (2002) Life Sci. , vol.72 , pp. 23-34
    • Kuo, P.L.1    Chiang, L.C.2    Lin, C.C.3
  • 89
    • 0037222094 scopus 로고    scopus 로고
    • Green tea constituent (-)-epigallocatechin-3-gallate inhibits Hep G2 cell proliferation and induces apoptosis through p53-dependent and Fas-mediated pathways
    • Kuo P.L., Lin C.C. Green tea constituent (-)-epigallocatechin-3-gallate inhibits Hep G2 cell proliferation and induces apoptosis through p53-dependent and Fas-mediated pathways. J. Biomed. Sci. 2003, 10:219-227.
    • (2003) J. Biomed. Sci. , vol.10 , pp. 219-227
    • Kuo, P.L.1    Lin, C.C.2
  • 90
    • 61449158898 scopus 로고    scopus 로고
    • Isoflavone consumption and subsequent risk of hepatocellular carcinoma in a population-based prospective cohort of Japanese men and women
    • JPHC Study Group
    • Kurahashi N., Inoue M., Iwasaki M., Tanaka Y., Mizokami M., Tsugane S. Isoflavone consumption and subsequent risk of hepatocellular carcinoma in a population-based prospective cohort of Japanese men and women. Int. J. Cancer 2009, 124:1644-1649. JPHC Study Group.
    • (2009) Int. J. Cancer , vol.124 , pp. 1644-1649
    • Kurahashi, N.1    Inoue, M.2    Iwasaki, M.3    Tanaka, Y.4    Mizokami, M.5    Tsugane, S.6
  • 91
    • 15044342684 scopus 로고    scopus 로고
    • Inhibition of cyclooxygenase-2 expression and restoration of gap junction intercellular communication in H-ras-transformed rat liver epithelial cells by caffeic acid phenethyl ester
    • Lee K.W., Chun K.S., Lee J.S., Kang K.S., Surh Y.J., Lee H.J. Inhibition of cyclooxygenase-2 expression and restoration of gap junction intercellular communication in H-ras-transformed rat liver epithelial cells by caffeic acid phenethyl ester. Ann. NY Acad. Sci. 2004, 1030:501-507.
    • (2004) Ann. NY Acad. Sci. , vol.1030 , pp. 501-507
    • Lee, K.W.1    Chun, K.S.2    Lee, J.S.3    Kang, K.S.4    Surh, Y.J.5    Lee, H.J.6
  • 92
    • 1842431016 scopus 로고    scopus 로고
    • Involvement of NADPH oxidase-mediated generation of reactive oxygen species in the apototic cell death by capsaicin in HepG2 human hepatoma cells
    • Lee Y.S., Kang Y.S., Lee J.S., Nicolova S., Kim J.A. Involvement of NADPH oxidase-mediated generation of reactive oxygen species in the apototic cell death by capsaicin in HepG2 human hepatoma cells. Free Radic. Res. 2004, 38(4):405-412.
    • (2004) Free Radic. Res. , vol.38 , Issue.4 , pp. 405-412
    • Lee, Y.S.1    Kang, Y.S.2    Lee, J.S.3    Nicolova, S.4    Kim, J.A.5
  • 93
    • 27744541598 scopus 로고    scopus 로고
    • Role of NADPH oxidase-mediated generation of reactive oxygen species in the mechanism of apoptosis induced by phenolic acids in HepG2 human hepatoma cells
    • Lee Y.S. Role of NADPH oxidase-mediated generation of reactive oxygen species in the mechanism of apoptosis induced by phenolic acids in HepG2 human hepatoma cells. Arch. Pharm. Res. 2005, 28:1183-1189.
    • (2005) Arch. Pharm. Res. , vol.28 , pp. 1183-1189
    • Lee, Y.S.1
  • 94
    • 33644764655 scopus 로고    scopus 로고
    • Inhibitory effect of luteolin on hepatocyte growth factor/scatter factor-induced HepG2 cell invasion involving both MAPK/ERKs and PI3K-Akt pathways
    • Lee W.J., Wu L.F., Chen W.K., Wang C.J., Tseng T.H. Inhibitory effect of luteolin on hepatocyte growth factor/scatter factor-induced HepG2 cell invasion involving both MAPK/ERKs and PI3K-Akt pathways. Chem. Biol. Interact. 2006, 160:123-133.
    • (2006) Chem. Biol. Interact. , vol.160 , pp. 123-133
    • Lee, W.J.1    Wu, L.F.2    Chen, W.K.3    Wang, C.J.4    Tseng, T.H.5
  • 95
    • 34247854884 scopus 로고    scopus 로고
    • Phenolic phytochemicals derived from red pine (Pinus densiflora) inhibit the invasion and migration of SK-Hep-1 human hepatocellular carcinoma cells
    • Lee S.J., Lee K.W., Hur H.J., Chun J.Y., Kim S.Y., Lee H.J. Phenolic phytochemicals derived from red pine (Pinus densiflora) inhibit the invasion and migration of SK-Hep-1 human hepatocellular carcinoma cells. Ann. NY Acad. Sci. 2007, 1095:536-544.
    • (2007) Ann. NY Acad. Sci. , vol.1095 , pp. 536-544
    • Lee, S.J.1    Lee, K.W.2    Hur, H.J.3    Chun, J.Y.4    Kim, S.Y.5    Lee, H.J.6
  • 96
    • 68249095178 scopus 로고    scopus 로고
    • (-)-Epigallocatechin-3-gallate induces apoptosis of human hepatoma cells by mitochondrial pathways related to reactive oxygen species
    • Li W., Nie S., Yu Q., Xie M. (-)-Epigallocatechin-3-gallate induces apoptosis of human hepatoma cells by mitochondrial pathways related to reactive oxygen species. J. Agric. Food Chem. 2009, 57:6685-6691.
    • (2009) J. Agric. Food Chem. , vol.57 , pp. 6685-6691
    • Li, W.1    Nie, S.2    Yu, Q.3    Xie, M.4
  • 97
    • 77953198124 scopus 로고    scopus 로고
    • Regulation of microRNAs by natural agents: an emerging field in chemoprevention and chemotherapy research
    • Li Y., Kong D., Wang Z., Sarkar F.H. Regulation of microRNAs by natural agents: an emerging field in chemoprevention and chemotherapy research. Pharm. Res. 2010, 27:1027-1041.
    • (2010) Pharm. Res. , vol.27 , pp. 1027-1041
    • Li, Y.1    Kong, D.2    Wang, Z.3    Sarkar, F.H.4
  • 98
    • 77953188130 scopus 로고    scopus 로고
    • Green tea catechins augment the antitumor activity of doxorubicin in an in vivo mouse model for chemoresistant liver cancer
    • Liang G., Tang A., Lin X., Li L., Zhang S., Huang Z., Tang H., Li Q.Q. Green tea catechins augment the antitumor activity of doxorubicin in an in vivo mouse model for chemoresistant liver cancer. Int. J. Oncol. 2010, 37:111-123.
    • (2010) Int. J. Oncol. , vol.37 , pp. 111-123
    • Liang, G.1    Tang, A.2    Lin, X.3    Li, L.4    Zhang, S.5    Huang, Z.6    Tang, H.7    Li, Q.Q.8
  • 99
    • 0031813252 scopus 로고    scopus 로고
    • Curcumin inhibits SK-Hep-1 hepatocellular carcinoma cell invasion in vitro and suppresses matrix metalloproteinase-9 secretion
    • Lin L.I., Ke Y.F., Ko Y.C., Lin J.K. Curcumin inhibits SK-Hep-1 hepatocellular carcinoma cell invasion in vitro and suppresses matrix metalloproteinase-9 secretion. Oncology 1998, 55:349-353.
    • (1998) Oncology , vol.55 , pp. 349-353
    • Lin, L.I.1    Ke, Y.F.2    Ko, Y.C.3    Lin, J.K.4
  • 100
    • 63949084699 scopus 로고    scopus 로고
    • Studies of structure-activity relationship on plant polyphenol-induced suppression of human liver cancer cells
    • Loa J., Chow P., Zhang K. Studies of structure-activity relationship on plant polyphenol-induced suppression of human liver cancer cells. Cancer Chemother. Pharmacol. 2009, 63:1007-1016.
    • (2009) Cancer Chemother. Pharmacol. , vol.63 , pp. 1007-1016
    • Loa, J.1    Chow, P.2    Zhang, K.3
  • 101
    • 0028008659 scopus 로고
    • Chili pepper consumption and gastric cancer in Mexico: a case-control study
    • Lopez-Carrillo L., Hernandez Avila M., Dubrow R. Chili pepper consumption and gastric cancer in Mexico: a case-control study. Am. J. Epidemiol. 1994, 139:263-271.
    • (1994) Am. J. Epidemiol. , vol.139 , pp. 263-271
    • Lopez-Carrillo, L.1    Hernandez Avila, M.2    Dubrow, R.3
  • 102
    • 77954617822 scopus 로고    scopus 로고
    • Effect of epigallocatechin-3-gallate on the invasiveness of hepatocarcinoma cells in vitro
    • Lu L., Liu H.M., Tang W.X. Effect of epigallocatechin-3-gallate on the invasiveness of hepatocarcinoma cells in vitro. Zhonghua Gan Zang Bing Za Zhi. 2007, 15:825-827.
    • (2007) Zhonghua Gan Zang Bing Za Zhi. , vol.15 , pp. 825-827
    • Lu, L.1    Liu, H.M.2    Tang, W.X.3
  • 103
    • 78649758314 scopus 로고    scopus 로고
    • Recent advances in the study on capsaicinoids and capsinoids
    • Luo X.J., Peng J., Li Y.J. Recent advances in the study on capsaicinoids and capsinoids. Eur. J. Pharmacol. 2011, 10, 650(1):1-7.
    • (2011) Eur. J. Pharmacol. , Issue.1 , pp. 1-7
    • Luo, X.J.1    Peng, J.2    Li, Y.J.3
  • 106
    • 58149247844 scopus 로고    scopus 로고
    • Phytochemicals as potential chemopreventive and chemotherapeutic agents in hepatocarcinogenesis
    • Mann C.D., Neal C.P., Garcea G., Manson M.M., Dennison A.R., Berry D.P. Phytochemicals as potential chemopreventive and chemotherapeutic agents in hepatocarcinogenesis. Eur. J. Cancer Prev. 2009, 18(1):13-25.
    • (2009) Eur. J. Cancer Prev. , vol.18 , Issue.1 , pp. 13-25
    • Mann, C.D.1    Neal, C.P.2    Garcea, G.3    Manson, M.M.4    Dennison, A.R.5    Berry, D.P.6
  • 107
    • 0029844747 scopus 로고    scopus 로고
    • Inhibitory effects of tea catechins, black tea extract and oolong tea extract on hepatocarcinogenesis in rat
    • Matsumoto N., Kohri T., Okushio K., Hara Y. Inhibitory effects of tea catechins, black tea extract and oolong tea extract on hepatocarcinogenesis in rat. Jpn. J. Cancer Res. 1996, 87:1034-1048.
    • (1996) Jpn. J. Cancer Res. , vol.87 , pp. 1034-1048
    • Matsumoto, N.1    Kohri, T.2    Okushio, K.3    Hara, Y.4
  • 108
    • 38049152791 scopus 로고    scopus 로고
    • Epigenetic regulation of microRNA-370 by interleukin-6 in malignant human cholangiocytes
    • Meng F., Wehbe-Janek H., Henson R., Smith H., Patel T. Epigenetic regulation of microRNA-370 by interleukin-6 in malignant human cholangiocytes. Oncogene 2008, 27:378-386.
    • (2008) Oncogene , vol.27 , pp. 378-386
    • Meng, F.1    Wehbe-Janek, H.2    Henson, R.3    Smith, H.4    Patel, T.5
  • 112
    • 80052028983 scopus 로고    scopus 로고
    • Potential applications of curcumin and its novel synthetic analogs and nanotechnology-based formulations in cancer prevention and therapy
    • Mimeault M., Batra S.K. Potential applications of curcumin and its novel synthetic analogs and nanotechnology-based formulations in cancer prevention and therapy. Chin. Med. 2011, 23(6):31.
    • (2011) Chin. Med. , vol.23 , Issue.6 , pp. 31
    • Mimeault, M.1    Batra, S.K.2
  • 113
    • 64249098061 scopus 로고    scopus 로고
    • Prevention of chemically induced mammary tumorigenesis by daidzein in pre-pubertal rats: the role of peroxidative damage and antioxidative enzymes
    • Mishra P., Kar A., Kale R.K. Prevention of chemically induced mammary tumorigenesis by daidzein in pre-pubertal rats: the role of peroxidative damage and antioxidative enzymes. Mol. Cell Biochem. 2009, 325:149-157.
    • (2009) Mol. Cell Biochem. , vol.325 , pp. 149-157
    • Mishra, P.1    Kar, A.2    Kale, R.K.3
  • 114
    • 12444322028 scopus 로고    scopus 로고
    • Resveratrol inhibits hepatoma cell invasion by suppressing gene expression of hepatocyte growth factor via its reactive oxygen species-scavenging property
    • Miura D., Miura Y., Yagasaki K. Resveratrol inhibits hepatoma cell invasion by suppressing gene expression of hepatocyte growth factor via its reactive oxygen species-scavenging property. Clin. Exp. Metastasis 2004, 21:445-451.
    • (2004) Clin. Exp. Metastasis , vol.21 , pp. 445-451
    • Miura, D.1    Miura, Y.2    Yagasaki, K.3
  • 115
    • 48749115799 scopus 로고    scopus 로고
    • Effects of silibinin on cell growth and invasive properties of a human hepatocellular carcinoma cell line, HepG-2, through inhibition of extracellular signal-regulated kinase 1/2 phosphorylation
    • Momeny M., Khorramizadeh M.R., Ghaffari S.H., Yousefi M., Yekaninejad M.S., Esmaeili R., Jahanshiri Z., Nooridaloii M.R. Effects of silibinin on cell growth and invasive properties of a human hepatocellular carcinoma cell line, HepG-2, through inhibition of extracellular signal-regulated kinase 1/2 phosphorylation. Eur. J. Pharmacol. 2008, 591:13-20.
    • (2008) Eur. J. Pharmacol. , vol.591 , pp. 13-20
    • Momeny, M.1    Khorramizadeh, M.R.2    Ghaffari, S.H.3    Yousefi, M.4    Yekaninejad, M.S.5    Esmaeili, R.6    Jahanshiri, Z.7    Nooridaloii, M.R.8
  • 116
    • 0037202905 scopus 로고    scopus 로고
    • Prevention of liver cancer: basic and clinical aspects
    • Moriwaki H. Prevention of liver cancer: basic and clinical aspects. Exp. Mol. Med. 2002, 34:319-325.
    • (2002) Exp. Mol. Med. , vol.34 , pp. 319-325
    • Moriwaki, H.1
  • 117
    • 33646157967 scopus 로고    scopus 로고
    • Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and non-tumorous tissues
    • Murakami Y., Yasuda T., Saigo K., Urashima T., Toyoda H., Okanoue T., Shimotohno K. Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and non-tumorous tissues. Oncogene 2006, 25:2537-2545.
    • (2006) Oncogene , vol.25 , pp. 2537-2545
    • Murakami, Y.1    Yasuda, T.2    Saigo, K.3    Urashima, T.4    Toyoda, H.5    Okanoue, T.6    Shimotohno, K.7
  • 118
    • 0034739332 scopus 로고    scopus 로고
    • Restoration of gap junctional intercellular communication by caffeic acid phenethyl ester (CAPE) in a ras-transformed rat liver epithelial cell line
    • Na H.K., Wilson M.R., Kang K.S., Chang C.C., Grunberger D., Trosko J.E. Restoration of gap junctional intercellular communication by caffeic acid phenethyl ester (CAPE) in a ras-transformed rat liver epithelial cell line. Cancer Lett. 2000, 157:31-38.
    • (2000) Cancer Lett. , vol.157 , pp. 31-38
    • Na, H.K.1    Wilson, M.R.2    Kang, K.S.3    Chang, C.C.4    Grunberger, D.5    Trosko, J.E.6
  • 119
    • 0033506299 scopus 로고    scopus 로고
    • Prognostic factors after hepatic resection for hepatocellular carcinoma associated with Child-Turcotte class B and C cirrhosis
    • Nagasue N., Kohno H., Tachibana M., Yamanoi A., Ohmori H., El-Assal O.N. Prognostic factors after hepatic resection for hepatocellular carcinoma associated with Child-Turcotte class B and C cirrhosis. Ann. Surg. 1999, 229:84-90.
    • (1999) Ann. Surg. , vol.229 , pp. 84-90
    • Nagasue, N.1    Kohno, H.2    Tachibana, M.3    Yamanoi, A.4    Ohmori, H.5    El-Assal, O.N.6
  • 120
    • 0038644536 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis: summary of an AASLD single topic conference
    • Neuschwander-Tetri B.A., Caldwell S.H. Nonalcoholic steatohepatitis: summary of an AASLD single topic conference. Hepatology 2003, 37:1202-1219.
    • (2003) Hepatology , vol.37 , pp. 1202-1219
    • Neuschwander-Tetri, B.A.1    Caldwell, S.H.2
  • 121
    • 77953457718 scopus 로고    scopus 로고
    • Down-regulation of Notch1 signaling inhibits tumor growth in human hepatocellular carcinoma
    • Ning L., Wentworth L., Chen H., Weber S.M. Down-regulation of Notch1 signaling inhibits tumor growth in human hepatocellular carcinoma. Am. J. Trans. Res. 2009, 1:358-366.
    • (2009) Am. J. Trans. Res. , vol.1 , pp. 358-366
    • Ning, L.1    Wentworth, L.2    Chen, H.3    Weber, S.M.4
  • 122
    • 0028293659 scopus 로고
    • Inhibitory effects of (-)-epigallocatechin gallate on spontaneous hepatoma in C3H/HeNCrj mice and human hepatoma-derived PLC/PRF/5 cells
    • Nishida H., Omori M., Fukutomi Y., Ninomiya M., Nishiwaki S., Suganuma M., Moriwaki H., Muto Y. Inhibitory effects of (-)-epigallocatechin gallate on spontaneous hepatoma in C3H/HeNCrj mice and human hepatoma-derived PLC/PRF/5 cells. Jpn. J. Cancer Res. 1994, 85:221-225.
    • (1994) Jpn. J. Cancer Res. , vol.85 , pp. 221-225
    • Nishida, H.1    Omori, M.2    Fukutomi, Y.3    Ninomiya, M.4    Nishiwaki, S.5    Suganuma, M.6    Moriwaki, H.7    Muto, Y.8
  • 124
    • 77953724339 scopus 로고    scopus 로고
    • The changing pattern of epidemiology in hepatocellular carcinoma
    • Nordenstedt H., White D.L., El-Serag H.B. The changing pattern of epidemiology in hepatocellular carcinoma. Dig. Liver Dis. 2010, 42(Suppl. 1):206-214.
    • (2010) Dig. Liver Dis. , vol.42 , Issue.SUPPL. 1 , pp. 206-214
    • Nordenstedt, H.1    White, D.L.2    El-Serag, H.B.3
  • 125
    • 19344367506 scopus 로고    scopus 로고
    • Antitumor effects of curcumin, alone or in combination with cisplatin or doxorubicin, on human hepatic cancer cells. Analysis of their possible relationship to changes in NF-kB activation levels and in IAP gene expression
    • Notarbartolo M., Poma P., Perri D., Dusonchet L., Cervello M., D'Alessandro N. Antitumor effects of curcumin, alone or in combination with cisplatin or doxorubicin, on human hepatic cancer cells. Analysis of their possible relationship to changes in NF-kB activation levels and in IAP gene expression. Cancer Lett. 2005, 224:53-65.
    • (2005) Cancer Lett. , vol.224 , pp. 53-65
    • Notarbartolo, M.1    Poma, P.2    Perri, D.3    Dusonchet, L.4    Cervello, M.5    D'Alessandro, N.6
  • 126
    • 33750513819 scopus 로고    scopus 로고
    • Resveratrol exerts its antiproliferative effect on HepG2 hepatocellular carcinoma cells, by inducing cell cycle arrest, and NOS activation
    • Notas G., Nifli A.P., Kampa M., Vercauteren J., Kouroumalis E., Castanas E. Resveratrol exerts its antiproliferative effect on HepG2 hepatocellular carcinoma cells, by inducing cell cycle arrest, and NOS activation. Biochim. Biophys. Acta 2006, 1760:1657-1666.
    • (2006) Biochim. Biophys. Acta , vol.1760 , pp. 1657-1666
    • Notas, G.1    Nifli, A.P.2    Kampa, M.3    Vercauteren, J.4    Kouroumalis, E.5    Castanas, E.6
  • 127
    • 0345600100 scopus 로고    scopus 로고
    • Prevention of intrahepatic metastasis by curcumin in an orthotopic implantation model
    • Ohashi Y., Tsuchiya Y., Koizumi K., Sakurai H., Saiki I. Prevention of intrahepatic metastasis by curcumin in an orthotopic implantation model. Oncology 2003, 65:250-258.
    • (2003) Oncology , vol.65 , pp. 250-258
    • Ohashi, Y.1    Tsuchiya, Y.2    Koizumi, K.3    Sakurai, H.4    Saiki, I.5
  • 128
    • 38949182247 scopus 로고    scopus 로고
    • Metabolic conversion of dietary quercetin from its conjugate to active aglycone following the induction of hepatocarcinogenesis in fisher 344 rats
    • Oi N., Hashimoto T., Kanazawa K. Metabolic conversion of dietary quercetin from its conjugate to active aglycone following the induction of hepatocarcinogenesis in fisher 344 rats. J. Agric. Food Chem. 2008, 56:577-583.
    • (2008) J. Agric. Food Chem. , vol.56 , pp. 577-583
    • Oi, N.1    Hashimoto, T.2    Kanazawa, K.3
  • 129
    • 67650105291 scopus 로고    scopus 로고
    • Pterostilbene inhibited tumor invasion via suppressing multiple signal transduction pathways in human hepatocellular carcinoma cells
    • Pan M.H., Chiou Y.S., Chen W.J., Wang J.M., Badmaev V., Ho C.T. Pterostilbene inhibited tumor invasion via suppressing multiple signal transduction pathways in human hepatocellular carcinoma cells. Carcinogenesis 2009, 30:1234-1242.
    • (2009) Carcinogenesis , vol.30 , pp. 1234-1242
    • Pan, M.H.1    Chiou, Y.S.2    Chen, W.J.3    Wang, J.M.4    Badmaev, V.5    Ho, C.T.6
  • 130
    • 33746268320 scopus 로고    scopus 로고
    • Molecular pathways in hepatocellular carcinoma
    • Pang R., Tse E., Poon R.T. Molecular pathways in hepatocellular carcinoma. Cancer Lett. 2006, 240:157-169.
    • (2006) Cancer Lett. , vol.240 , pp. 157-169
    • Pang, R.1    Tse, E.2    Poon, R.T.3
  • 131
    • 78650173217 scopus 로고    scopus 로고
    • Downregulation of cyclin D1 is associated with decreased levels of p38 MAP kinases, Akt/PKB and Pak1 during chemopreventive effects of resveratrol in liver cancer cells
    • Parekh P., Motiwale L., Naik N., Rao K.V. Downregulation of cyclin D1 is associated with decreased levels of p38 MAP kinases, Akt/PKB and Pak1 during chemopreventive effects of resveratrol in liver cancer cells. Exp. Toxicol. Pathol. 2011, 63:167-173.
    • (2011) Exp. Toxicol. Pathol. , vol.63 , pp. 167-173
    • Parekh, P.1    Motiwale, L.2    Naik, N.3    Rao, K.V.4
  • 132
    • 0031960861 scopus 로고    scopus 로고
    • Effects of silymarin in alcoholic patients with cirrhosis of the liver: results of a controlled, double-blind, randomized and multicenter trial
    • Pares A., Planas R., Torres M., Caballeria J., Viver J.M., Acero D., Panes J., Rigau J., Santos J., Rodes J. Effects of silymarin in alcoholic patients with cirrhosis of the liver: results of a controlled, double-blind, randomized and multicenter trial. J. Hepatol. 1998, 28:615-621.
    • (1998) J. Hepatol. , vol.28 , pp. 615-621
    • Pares, A.1    Planas, R.2    Torres, M.3    Caballeria, J.4    Viver, J.M.5    Acero, D.6    Panes, J.7    Rigau, J.8    Santos, J.9    Rodes, J.10
  • 133
    • 0035347187 scopus 로고    scopus 로고
    • Synergistic effects of dexamethasone and genistein on the expression of Cdk inhibitor p21WAF1/CIP1 in human hepatocellular and colorectal carcinoma cells
    • Park J.H., Oh E.J., Choi Y.H., Kang C.D., Kang H.S., Kim D.K., Kang K.I., Yoo M.A. Synergistic effects of dexamethasone and genistein on the expression of Cdk inhibitor p21WAF1/CIP1 in human hepatocellular and colorectal carcinoma cells. Int. J. Oncol. 2001, 18:997-1002.
    • (2001) Int. J. Oncol. , vol.18 , pp. 997-1002
    • Park, J.H.1    Oh, E.J.2    Choi, Y.H.3    Kang, C.D.4    Kang, H.S.5    Kim, D.K.6    Kang, K.I.7    Yoo, M.A.8
  • 134
    • 0035888074 scopus 로고    scopus 로고
    • Estimating the world cancer burden: Globocan 2000
    • Parkin D.M., Bray F., Ferlay J., Pisani P. Estimating the world cancer burden: Globocan 2000. Int. J. Cancer 2001, 94:153-156.
    • (2001) Int. J. Cancer , vol.94 , pp. 153-156
    • Parkin, D.M.1    Bray, F.2    Ferlay, J.3    Pisani, P.4
  • 135
    • 77957355158 scopus 로고    scopus 로고
    • Clinical pharmacology of resveratrol and its metabolites in colorectal cancer patients
    • Patel K.R., Brown V.A., Jones D.J., Britton R.G., Hemingway D., et al. Clinical pharmacology of resveratrol and its metabolites in colorectal cancer patients. Cancer Res. 2010, 70:7392-7399.
    • (2010) Cancer Res. , vol.70 , pp. 7392-7399
    • Patel, K.R.1    Brown, V.A.2    Jones, D.J.3    Britton, R.G.4    Hemingway, D.5
  • 137
    • 0029566974 scopus 로고
    • Chemoprevention of diethylnitrosamine-induced liver foci and hepatocellular adenomas in C3H mice
    • Pereira M.A. Chemoprevention of diethylnitrosamine-induced liver foci and hepatocellular adenomas in C3H mice. Anticancer Res. 1995, 15:1953-1956.
    • (1995) Anticancer Res. , vol.15 , pp. 1953-1956
    • Pereira, M.A.1
  • 138
    • 0031799304 scopus 로고    scopus 로고
    • Mechanisms of anticarcinogenic properties of curcumin: the effect of curcumin on glutathione linked detoxification enzymes in rat liver
    • Piper J.T., Singhal S.S., Salameh M.S., Torman R.T., Awasthi Y.C., Awasthi S. Mechanisms of anticarcinogenic properties of curcumin: the effect of curcumin on glutathione linked detoxification enzymes in rat liver. Int. J. Biochem. Cell Biol. 1998, 30:445-456.
    • (1998) Int. J. Biochem. Cell Biol. , vol.30 , pp. 445-456
    • Piper, J.T.1    Singhal, S.S.2    Salameh, M.S.3    Torman, R.T.4    Awasthi, Y.C.5    Awasthi, S.6
  • 139
    • 0036208524 scopus 로고    scopus 로고
    • Locoregional therapies for hepatocellular carcinoma: a critical review from the surgeon's perspective
    • Poon R.T., Fan S.T., Tsang F.H., Wong J. Locoregional therapies for hepatocellular carcinoma: a critical review from the surgeon's perspective. Ann. Surg. 2002, 235:466-486.
    • (2002) Ann. Surg. , vol.235 , pp. 466-486
    • Poon, R.T.1    Fan, S.T.2    Tsang, F.H.3    Wong, J.4
  • 140
    • 7044270445 scopus 로고    scopus 로고
    • Resection prior to liver transplantation for hepatocellular carcinoma: a strategy of optimizing the role of resection and transplantation in cirrhotic patients with preserved liver function
    • Poon R.T., Fan S.T. Resection prior to liver transplantation for hepatocellular carcinoma: a strategy of optimizing the role of resection and transplantation in cirrhotic patients with preserved liver function. Liver Transpl. 2004, 10:813-815.
    • (2004) Liver Transpl. , vol.10 , pp. 813-815
    • Poon, R.T.1    Fan, S.T.2
  • 142
    • 48649095089 scopus 로고    scopus 로고
    • Cancer chemoprevention and chemotherapy: dietary polyphenols and signalling pathways
    • Ramos S. Cancer chemoprevention and chemotherapy: dietary polyphenols and signalling pathways. Mol. Nutr. Food Res. 2008, 52:507-526.
    • (2008) Mol. Nutr. Food Res. , vol.52 , pp. 507-526
    • Ramos, S.1
  • 143
    • 33646828371 scopus 로고    scopus 로고
    • Suppression of N-nitrosodiethylamine induced hepatocarcinogenesis by silymarin in rats
    • Ramakrishnan G., Raghavendran H.R., Vinodhkumar R., Devaki T. Suppression of N-nitrosodiethylamine induced hepatocarcinogenesis by silymarin in rats. Chem. Biol. Interact. 2006, 161:104-114.
    • (2006) Chem. Biol. Interact. , vol.161 , pp. 104-114
    • Ramakrishnan, G.1    Raghavendran, H.R.2    Vinodhkumar, R.3    Devaki, T.4
  • 145
    • 64649086559 scopus 로고    scopus 로고
    • Silymarin attenuated mast cell recruitment thereby decreased the expressions of matrix metalloproteinases-2 and 9 in rat liver carcinogenesis
    • Ramakrishnan G., Jagan S., Kamaraj S., Anandakumar P., Devaki T. Silymarin attenuated mast cell recruitment thereby decreased the expressions of matrix metalloproteinases-2 and 9 in rat liver carcinogenesis. Invest. New Drugs 2009, 27:233-240.
    • (2009) Invest. New Drugs , vol.27 , pp. 233-240
    • Ramakrishnan, G.1    Jagan, S.2    Kamaraj, S.3    Anandakumar, P.4    Devaki, T.5
  • 146
    • 77950355235 scopus 로고    scopus 로고
    • Trans-Resveratrol as a neuroprotectant
    • Robb E.L., Stuart J.A. Trans-Resveratrol as a neuroprotectant. Molecules 2010, 15:1196-1212.
    • (2010) Molecules , vol.15 , pp. 1196-1212
    • Robb, E.L.1    Stuart, J.A.2
  • 147
    • 0038408778 scopus 로고    scopus 로고
    • Phenolic acids in foods: an overview of analytical methodology
    • Robbins R.J. Phenolic acids in foods: an overview of analytical methodology. J. Agric. Food Chem. 2003, 51:2866-2887.
    • (2003) J. Agric. Food Chem. , vol.51 , pp. 2866-2887
    • Robbins, R.J.1
  • 148
    • 0036195961 scopus 로고    scopus 로고
    • The phytoestrogen daidzein affects the antioxidant enzyme system of rat hepatoma H4IIE cells
    • Röhrdanz E., Ohler S., Tran-Thi Q.H., Kahl R. The phytoestrogen daidzein affects the antioxidant enzyme system of rat hepatoma H4IIE cells. J. Nutr. 2002, 132:370-375.
    • (2002) J. Nutr. , vol.132 , pp. 370-375
    • Röhrdanz, E.1    Ohler, S.2    Tran-Thi, Q.H.3    Kahl, R.4
  • 150
    • 81855164783 scopus 로고    scopus 로고
    • The flavonoid quercetin in disease prevention and therapy: facts and fancies
    • Russo M., Spagnuolo C., Tedesco I., Bilotto S., Russo G.L. The flavonoid quercetin in disease prevention and therapy: facts and fancies. Biochem. Pharmacol. 2012, 83(1):6-15.
    • (2012) Biochem. Pharmacol. , vol.83 , Issue.1 , pp. 6-15
    • Russo, M.1    Spagnuolo, C.2    Tedesco, I.3    Bilotto, S.4    Russo, G.L.5
  • 152
    • 33646411225 scopus 로고    scopus 로고
    • Luteolin promotes degradation in signal transducer and activator of transcription 3 in human hepatoma cells: an implication for the antitumor potential of flavonoids
    • Selvendiran K., Koga H., Ueno T., Yoshida T., Maeyama M., Torimura T., Yano H., Kojiro M., Sata M. Luteolin promotes degradation in signal transducer and activator of transcription 3 in human hepatoma cells: an implication for the antitumor potential of flavonoids. Cancer Res. 2006, 66:4826-4834.
    • (2006) Cancer Res. , vol.66 , pp. 4826-4834
    • Selvendiran, K.1    Koga, H.2    Ueno, T.3    Yoshida, T.4    Maeyama, M.5    Torimura, T.6    Yano, H.7    Kojiro, M.8    Sata, M.9
  • 155
    • 67949118808 scopus 로고    scopus 로고
    • Preventive effect of the flavonoid, quercetin, on hepatic cancer in rats via oxidant/antioxidant activity: molecular and histological evidences
    • Seufi A.M., Ibrahim S.S., Elmaghraby T.K., Hafez E.E. Preventive effect of the flavonoid, quercetin, on hepatic cancer in rats via oxidant/antioxidant activity: molecular and histological evidences. J. Exp. Clin. Cancer Res. 2009, 28:80.
    • (2009) J. Exp. Clin. Cancer Res. , vol.28 , pp. 80
    • Seufi, A.M.1    Ibrahim, S.S.2    Elmaghraby, T.K.3    Hafez, E.E.4
  • 156
    • 79955637308 scopus 로고    scopus 로고
    • Highly loaded, sustained-release microparticles of curcumin for chemoprevention
    • Shahani K., Panyam J. Highly loaded, sustained-release microparticles of curcumin for chemoprevention. J. Pharm. Sci. 2011, 100(7):2599-2609.
    • (2011) J. Pharm. Sci. , vol.100 , Issue.7 , pp. 2599-2609
    • Shahani, K.1    Panyam, J.2
  • 157
    • 77952298545 scopus 로고    scopus 로고
    • Inhibition of Hsp27 and Hsp40 potentiates 5-fluorouracil and carboplatin mediated cell killing in hepatoma cells
    • Sharma A., Upadhyay A.K., Bhat M.K. Inhibition of Hsp27 and Hsp40 potentiates 5-fluorouracil and carboplatin mediated cell killing in hepatoma cells. Cancer Biol. Ther. 2009, 8:2106-2113.
    • (2009) Cancer Biol. Ther. , vol.8 , pp. 2106-2113
    • Sharma, A.1    Upadhyay, A.K.2    Bhat, M.K.3
  • 161
    • 70349585440 scopus 로고    scopus 로고
    • (-)-Epigallocatechin gallate suppresses the growth of human hepatocellular carcinoma cells by inhibiting activation of the vascular endothelial growth factor-vascular endothelial growth factor receptor axis
    • Shirakami Y., Shimizu M., Adachi S., Sakai H., Nakagawa T., Yasuda Y., Tsurumi H., Hara Y., Moriwaki H. (-)-Epigallocatechin gallate suppresses the growth of human hepatocellular carcinoma cells by inhibiting activation of the vascular endothelial growth factor-vascular endothelial growth factor receptor axis. Cancer Sci. 2009, 100:1957-1962.
    • (2009) Cancer Sci. , vol.100 , pp. 1957-1962
    • Shirakami, Y.1    Shimizu, M.2    Adachi, S.3    Sakai, H.4    Nakagawa, T.5    Yasuda, Y.6    Tsurumi, H.7    Hara, Y.8    Moriwaki, H.9
  • 162
    • 0038647594 scopus 로고    scopus 로고
    • Suppression of altered hepatic foci development by curcumin in wistar rats
    • Shukla Y., Arora A. Suppression of altered hepatic foci development by curcumin in wistar rats. Nutr. Cancer 2003, 45:53-59.
    • (2003) Nutr. Cancer , vol.45 , pp. 53-59
    • Shukla, Y.1    Arora, A.2
  • 163
    • 77952270920 scopus 로고    scopus 로고
    • Cardiovascular friendly natural products: a promising approach in the management of CVD
    • Shukla S.K., Gupta S., Ojha S.K., Sharma S.B. Cardiovascular friendly natural products: a promising approach in the management of CVD. Nat. Prod. Res. 2010, 24:873-898.
    • (2010) Nat. Prod. Res. , vol.24 , pp. 873-898
    • Shukla, S.K.1    Gupta, S.2    Ojha, S.K.3    Sharma, S.B.4
  • 165
    • 0030906612 scopus 로고    scopus 로고
    • Protective effect of food additives on aflatoxin-induced mutagenicity and hepatocarcinogenicity
    • Soni K.B., Lahiri M., Chackradeo P., Bhide S.V., Kuttan R. Protective effect of food additives on aflatoxin-induced mutagenicity and hepatocarcinogenicity. Cancer Lett. 1997, 115:129-133.
    • (1997) Cancer Lett. , vol.115 , pp. 129-133
    • Soni, K.B.1    Lahiri, M.2    Chackradeo, P.3    Bhide, S.V.4    Kuttan, R.5
  • 166
    • 27644477094 scopus 로고    scopus 로고
    • Cancer chemoprevention: scientific promise, clinical uncertainty
    • Sporn M.B., Liby K.T. Cancer chemoprevention: scientific promise, clinical uncertainty. Nat. Clin. Pract. Oncol. 2005, 2:518-525.
    • (2005) Nat. Clin. Pract. Oncol. , vol.2 , pp. 518-525
    • Sporn, M.B.1    Liby, K.T.2
  • 167
    • 26944433864 scopus 로고    scopus 로고
    • Chemopreventive effects of embelin and curcumin against N-nitrosodiethylamine/phenobarbital-induced hepatocarcinogenesis in Wistar rats
    • Sreepriya M., Bali G. Chemopreventive effects of embelin and curcumin against N-nitrosodiethylamine/phenobarbital-induced hepatocarcinogenesis in Wistar rats. Fitoterapia 2005, 76:549-555.
    • (2005) Fitoterapia , vol.76 , pp. 549-555
    • Sreepriya, M.1    Bali, G.2
  • 168
    • 34447321309 scopus 로고    scopus 로고
    • Cytogenetic effects of grape extracts (Vitis vinifera) and polyphenols on mitomycin C-induced sister chromatid exchanges (SCEs) in human blood lymphocytes
    • Stagos D., Spanou C., Margariti M., Stathopoulos C., Mamuris Z., Kazantzoglou G., Magiatis P., Kouretas D. Cytogenetic effects of grape extracts (Vitis vinifera) and polyphenols on mitomycin C-induced sister chromatid exchanges (SCEs) in human blood lymphocytes. J. Agric. Food Chem. 2007, 55:5246-5252.
    • (2007) J. Agric. Food Chem. , vol.55 , pp. 5246-5252
    • Stagos, D.1    Spanou, C.2    Margariti, M.3    Stathopoulos, C.4    Mamuris, Z.5    Kazantzoglou, G.6    Magiatis, P.7    Kouretas, D.8
  • 169
    • 33751058881 scopus 로고    scopus 로고
    • Time- and concentration-dependent effects of resveratrol in HL-60 and HepG2 cells
    • Stervbo U., Vang O., Bonnesen C. Time- and concentration-dependent effects of resveratrol in HL-60 and HepG2 cells. Cell Prolif. 2006, 39:479-493.
    • (2006) Cell Prolif. , vol.39 , pp. 479-493
    • Stervbo, U.1    Vang, O.2    Bonnesen, C.3
  • 170
    • 0038308563 scopus 로고    scopus 로고
    • Effects of soy isoflavones on apoptosis induction and G2-M arrest in human hepatoma cells involvement of caspase-3 activation, Bcl-2 and Bcl-XL downregulation, and Cdc2 kinase activity
    • Su S.J., Chow N.H., Kung M.L., Hung T.C., Chang K.L. Effects of soy isoflavones on apoptosis induction and G2-M arrest in human hepatoma cells involvement of caspase-3 activation, Bcl-2 and Bcl-XL downregulation, and Cdc2 kinase activity. Nutr Cancer 2003, 45:113-123.
    • (2003) Nutr Cancer , vol.45 , pp. 113-123
    • Su, S.J.1    Chow, N.H.2    Kung, M.L.3    Hung, T.C.4    Chang, K.L.5
  • 173
    • 0030986660 scopus 로고    scopus 로고
    • Inhibition by green tea extract of diethylnitrosamine-initiated but not choline-deficient, l-amino acid-defined diet-associated development of putative preneoplastic, glutathione S-transferase placental form-positive lesions in rat liver
    • Tamura K., Nakae D., Horiguchi K., Akai H., Kobayashi Y., Satoh H., Tsujiuchi T., Denda A., Konishi Y. Inhibition by green tea extract of diethylnitrosamine-initiated but not choline-deficient, l-amino acid-defined diet-associated development of putative preneoplastic, glutathione S-transferase placental form-positive lesions in rat liver. Jpn. J. Cancer Res. 1997, 88(4):356-362.
    • (1997) Jpn. J. Cancer Res. , vol.88 , Issue.4 , pp. 356-362
    • Tamura, K.1    Nakae, D.2    Horiguchi, K.3    Akai, H.4    Kobayashi, Y.5    Satoh, H.6    Tsujiuchi, T.7    Denda, A.8    Konishi, Y.9
  • 174
    • 0024148358 scopus 로고    scopus 로고
    • Inhibitory effect of ellagic acid on N-2-fluorenylacetamide-induced liver carcinogenesis in male ACI/N rats
    • Tanaka T., Iwata H., Niwa K., Mori Y., Mori H. Inhibitory effect of ellagic acid on N-2-fluorenylacetamide-induced liver carcinogenesis in male ACI/N rats. Jpn. J. Cancer Res. 1998, 79:1297-1303.
    • (1998) Jpn. J. Cancer Res. , vol.79 , pp. 1297-1303
    • Tanaka, T.1    Iwata, H.2    Niwa, K.3    Mori, Y.4    Mori, H.5
  • 175
    • 0027460307 scopus 로고
    • Inhibitory effects of inhibitors of arachidonic acid metabolism on the evolution of rat liver preneoplastic foci into nodules and hepatocellular carcinomas with or without phenobarbital exposure
    • Tang Q., Denda A., Tsujiuchi T., Tsutsumi M., Amanuma T., Murata Y., Maruyama H., Konishi Y. Inhibitory effects of inhibitors of arachidonic acid metabolism on the evolution of rat liver preneoplastic foci into nodules and hepatocellular carcinomas with or without phenobarbital exposure. Jpn. J. Cancer Res. 1993, 84:120-127.
    • (1993) Jpn. J. Cancer Res. , vol.84 , pp. 120-127
    • Tang, Q.1    Denda, A.2    Tsujiuchi, T.3    Tsutsumi, M.4    Amanuma, T.5    Murata, Y.6    Maruyama, H.7    Konishi, Y.8
  • 176
    • 41549089719 scopus 로고    scopus 로고
    • Stabilization of p53 is involved in quercetin-induced cell cycle arrest and apoptosis in HepG2 cells
    • Tanigawa S., Fujii M., Hou D.X. Stabilization of p53 is involved in quercetin-induced cell cycle arrest and apoptosis in HepG2 cells. Biosci. Biotechnol. Biochem. 2008, 72:797-804.
    • (2008) Biosci. Biotechnol. Biochem. , vol.72 , pp. 797-804
    • Tanigawa, S.1    Fujii, M.2    Hou, D.X.3
  • 177
    • 54849409662 scopus 로고    scopus 로고
    • Effect of antioxidant phytochemicals on the hepatic tumor promoting activity of 3,3',4,4'-tetrachlorobiphenyl (PCB-77)
    • Tharappel J.C., Lehmler H.J., Srinivasan C., Robertson L.W., Spear B.T., Glauert H.P. Effect of antioxidant phytochemicals on the hepatic tumor promoting activity of 3,3',4,4'-tetrachlorobiphenyl (PCB-77). Food Chem. Toxicol. 2008, 46:3467-3474.
    • (2008) Food Chem. Toxicol. , vol.46 , pp. 3467-3474
    • Tharappel, J.C.1    Lehmler, H.J.2    Srinivasan, C.3    Robertson, L.W.4    Spear, B.T.5    Glauert, H.P.6
  • 178
    • 26944447173 scopus 로고    scopus 로고
    • Effects of a new pharmacological complex (silybin+vitamin-E+phospholipids) on some markers of the metabolic syndrome and of liver fibrosis in patients with hepatic steatosis Preliminary study
    • Real Sud Group 2
    • Trappoliere M., Federico A., Tuccillo C., de Sio I., Di Leva A., Niosi M., D'Auria M., Loguercio C. Effects of a new pharmacological complex (silybin+vitamin-E+phospholipids) on some markers of the metabolic syndrome and of liver fibrosis in patients with hepatic steatosis Preliminary study. Minerva Gastroenterol. Dietol. 2005, 1:193-199. Real Sud Group 2.
    • (2005) Minerva Gastroenterol. Dietol. , vol.1 , pp. 193-199
    • Trappoliere, M.1    Federico, A.2    Tuccillo, C.3    de Sio, I.4    Di Leva, A.5    Niosi, M.6    D'Auria, M.7    Loguercio, C.8
  • 179
    • 26944447173 scopus 로고    scopus 로고
    • Effects of a new pharmacological complex (silybin+vitamin-E+phospholipids) on some markers of the metabolic syndrome and of liver fibrosis in patients with hepatic steatosis. Preliminary study
    • Real Sud Group 2
    • Trappoliere M., Federico A., Tuccillo C., de Sio I., Di Leva A., Niosi M., D'Auria M., Loguercio C. Effects of a new pharmacological complex (silybin+vitamin-E+phospholipids) on some markers of the metabolic syndrome and of liver fibrosis in patients with hepatic steatosis. Preliminary study. Minerva Gastroenterol. Dietol. 2005, 51:193-199. Real Sud Group 2.
    • (2005) Minerva Gastroenterol. Dietol. , vol.51 , pp. 193-199
    • Trappoliere, M.1    Federico, A.2    Tuccillo, C.3    de Sio, I.4    Di Leva, A.5    Niosi, M.6    D'Auria, M.7    Loguercio, C.8
  • 180
    • 73949133652 scopus 로고    scopus 로고
    • Epigallocatechin gallate up-regulation of miR-16 and induction of apoptosis in human cancer cells
    • Tsang W.P., Kwok T.T. Epigallocatechin gallate up-regulation of miR-16 and induction of apoptosis in human cancer cells. J. Nutr. Biochem. 2010, 21:140-146.
    • (2010) J. Nutr. Biochem. , vol.21 , pp. 140-146
    • Tsang, W.P.1    Kwok, T.T.2
  • 181
    • 0028670227 scopus 로고
    • Chemopreventive effects of beta-carotene, alpha-tocopherol and five naturallyoccurring antioxidants on initiation of hepatocarcinogenesis by 2-amino-3-methylimidazo[4,5-f]quinoline in the rat
    • Tsuda H., Uehara N., Iwahori Y., Asamoto M., Iigo M., Nagao M., Matsumoto K., Ito M., Hirono I. Chemopreventive effects of beta-carotene, alpha-tocopherol and five naturallyoccurring antioxidants on initiation of hepatocarcinogenesis by 2-amino-3-methylimidazo[4,5-f]quinoline in the rat. Jpn. J. Cancer Res. 1994, 85:1214-1219.
    • (1994) Jpn. J. Cancer Res. , vol.85 , pp. 1214-1219
    • Tsuda, H.1    Uehara, N.2    Iwahori, Y.3    Asamoto, M.4    Iigo, M.5    Nagao, M.6    Matsumoto, K.7    Ito, M.8    Hirono, I.9
  • 182
    • 0038687703 scopus 로고    scopus 로고
    • Prevention of dual promoting effects of pentachlorophenol, an environmental pollutant, on diethylnitrosamine-induced hepato- and cholangiocarcinogenesis in mice by green tea infusion
    • Umemura T., Kai S., Hasegawa R., Kanki K., Kitamura Y., Nishikawa A., Hirose M. Prevention of dual promoting effects of pentachlorophenol, an environmental pollutant, on diethylnitrosamine-induced hepato- and cholangiocarcinogenesis in mice by green tea infusion. Carcinogenesis 2003, 24(6):1105-1109.
    • (2003) Carcinogenesis , vol.24 , Issue.6 , pp. 1105-1109
    • Umemura, T.1    Kai, S.2    Hasegawa, R.3    Kanki, K.4    Kitamura, Y.5    Nishikawa, A.6    Hirose, M.7
  • 185
    • 48049092377 scopus 로고    scopus 로고
    • Abrogation of G2/M arrest sensitizes curcumin-resistant hepatoma cells to apoptosis
    • Wang W.Z., Cheng J., Luo J., Zhuang S.M. Abrogation of G2/M arrest sensitizes curcumin-resistant hepatoma cells to apoptosis. FEBS Lett. 2008, 582:2689-2695.
    • (2008) FEBS Lett. , vol.582 , pp. 2689-2695
    • Wang, W.Z.1    Cheng, J.2    Luo, J.3    Zhuang, S.M.4
  • 186
    • 10044256702 scopus 로고    scopus 로고
    • Molecular mechanisms of the chemopreventive effects of resveratrol and its analogs in colorectal cancer: key role of polyamines?
    • Wolter F., Ulrich S., Stein J. Molecular mechanisms of the chemopreventive effects of resveratrol and its analogs in colorectal cancer: key role of polyamines?. J. Nutr. 2004, 134:3219-3222.
    • (2004) J. Nutr. , vol.134 , pp. 3219-3222
    • Wolter, F.1    Ulrich, S.2    Stein, J.3
  • 187
    • 79952412968 scopus 로고    scopus 로고
    • Expression characteristics of heparanase in colon carcinoma and its close relationship with cyclooxygenase-2 and angiogenesis
    • Wu B.W., Li D.F., Ke Z.F., Ma D., Li Y.J., Gang D., Zheng Z.G., Zhang K.J., Zhang Y.H. Expression characteristics of heparanase in colon carcinoma and its close relationship with cyclooxygenase-2 and angiogenesis. Hepatogastroenterology 2010, 57:1510-1514.
    • (2010) Hepatogastroenterology , vol.57 , pp. 1510-1514
    • Wu, B.W.1    Li, D.F.2    Ke, Z.F.3    Ma, D.4    Li, Y.J.5    Gang, D.6    Zheng, Z.G.7    Zhang, K.J.8    Zhang, Y.H.9
  • 188
    • 0032924841 scopus 로고    scopus 로고
    • Determination ofthe clonal origin of multiple human hepatocellular carcinomas by cloning and polymerase chain reaction of the integrated hepatitis B virus DNA
    • Yamamoto T., Kajino K., Kudo M., Sasaki Y., Arakawa Y., Hino O. Determination ofthe clonal origin of multiple human hepatocellular carcinomas by cloning and polymerase chain reaction of the integrated hepatitis B virus DNA. Hepatology 1999, 29:1446-1452.
    • (1999) Hepatology , vol.29 , pp. 1446-1452
    • Yamamoto, T.1    Kajino, K.2    Kudo, M.3    Sasaki, Y.4    Arakawa, Y.5    Hino, O.6
  • 190
    • 0042286578 scopus 로고    scopus 로고
    • Inhibitory effects of luteolin isolated from Ixeris sonchifolia Hance on the proliferation of HepG2 human hepatocellular carcinoma cells
    • Yee S.B., Lee J.H., Chung H.Y., Im K.S., Bae S.J., Choi J.S., Kim N.D. Inhibitory effects of luteolin isolated from Ixeris sonchifolia Hance on the proliferation of HepG2 human hepatocellular carcinoma cells. Arch. Pharm. Res. 2003, 26:151-156.
    • (2003) Arch. Pharm. Res. , vol.26 , pp. 151-156
    • Yee, S.B.1    Lee, J.H.2    Chung, H.Y.3    Im, K.S.4    Bae, S.J.5    Choi, J.S.6    Kim, N.D.7
  • 191
    • 33846879204 scopus 로고    scopus 로고
    • Genistein induces apoptosis in human hepatocellular carcinomas via interaction of endoplasmic reticulum stress and mitochondrial insult
    • Yeh T.C., Chiang P.C., Li T.K., Hsu J.L., Lin C.J., Wang S.W., Peng C.Y., Guh J.H. Genistein induces apoptosis in human hepatocellular carcinomas via interaction of endoplasmic reticulum stress and mitochondrial insult. Biochem. Pharmacol. 2007, 73:782-792.
    • (2007) Biochem. Pharmacol. , vol.73 , pp. 782-792
    • Yeh, T.C.1    Chiang, P.C.2    Li, T.K.3    Hsu, J.L.4    Lin, C.J.5    Wang, S.W.6    Peng, C.Y.7    Guh, J.H.8
  • 192
    • 67650905172 scopus 로고    scopus 로고
    • Apoptotic effects of protocatechuic acid in human breast, lung, liver, cervix, and prostate cancer cells: potential mechanisms of action
    • Yin M.C., Lin C.C., Wu H.C., Tsao S.M., Hsu C.K. Apoptotic effects of protocatechuic acid in human breast, lung, liver, cervix, and prostate cancer cells: potential mechanisms of action. J. Agric. Food Chem. 2009, 57:6468-6473.
    • (2009) J. Agric. Food Chem. , vol.57 , pp. 6468-6473
    • Yin, M.C.1    Lin, C.C.2    Wu, H.C.3    Tsao, S.M.4    Hsu, C.K.5
  • 193
    • 33745913944 scopus 로고    scopus 로고
    • Protocatechuic acid induces cell death in HepG2 hepatocellular carcinoma cells through a c-Jun N-terminal kinase-dependent mechanism
    • Yip E.C., Chan A.S., Pang H., Tam Y.K., Wong Y.H. Protocatechuic acid induces cell death in HepG2 hepatocellular carcinoma cells through a c-Jun N-terminal kinase-dependent mechanism. Cell Biol. Toxicol. 2006, 22:293-302.
    • (2006) Cell Biol. Toxicol. , vol.22 , pp. 293-302
    • Yip, E.C.1    Chan, A.S.2    Pang, H.3    Tam, Y.K.4    Wong, Y.H.5
  • 194
    • 67649413125 scopus 로고    scopus 로고
    • Proteomic identification of anti-cancer proteins in luteolin-treated human hepatoma Huh-7 cells
    • Yoo D.R., Jang Y.H., Jeon Y.K., Kim J.Y., Jeon W., Choi Y.J., Nam M.J. Proteomic identification of anti-cancer proteins in luteolin-treated human hepatoma Huh-7 cells. Cancer Lett. 2009, 282:48-54.
    • (2009) Cancer Lett. , vol.282 , pp. 48-54
    • Yoo, D.R.1    Jang, Y.H.2    Jeon, Y.K.3    Kim, J.Y.4    Jeon, W.5    Choi, Y.J.6    Nam, M.J.7
  • 196
    • 33644797877 scopus 로고    scopus 로고
    • Effects of curcumin on tumor angiogenesis and biomarkers, COX-2 and VEGF, in hepatocellular carcinoma cell-implanted nude mice
    • Yoysungnoen P., Wirachwong P., Bhattarakosol P., Niimi H., Patumraj S. Effects of curcumin on tumor angiogenesis and biomarkers, COX-2 and VEGF, in hepatocellular carcinoma cell-implanted nude mice. Clin. Hemorheol. Microcirc. 2006, 34:109-115.
    • (2006) Clin. Hemorheol. Microcirc. , vol.34 , pp. 109-115
    • Yoysungnoen, P.1    Wirachwong, P.2    Bhattarakosol, P.3    Niimi, H.4    Patumraj, S.5
  • 197
    • 27644508837 scopus 로고    scopus 로고
    • Resveratrol inhibits hypoxia-induced accumulation of hypoxia-inducible factor-1alpha and VEGF expression in human tongue squamous cell carcinoma and hepatoma cells
    • Zhang Q., Tang X., Lu Q.Y., Zhang Z.F., Brown J., Le A.D. Resveratrol inhibits hypoxia-induced accumulation of hypoxia-inducible factor-1alpha and VEGF expression in human tongue squamous cell carcinoma and hepatoma cells. Mol. Cancer Ther. 2005, 4:1465-1474.
    • (2005) Mol. Cancer Ther. , vol.4 , pp. 1465-1474
    • Zhang, Q.1    Tang, X.2    Lu, Q.Y.3    Zhang, Z.F.4    Brown, J.5    Le, A.D.6
  • 198
    • 33745058978 scopus 로고    scopus 로고
    • Green tea extract and (-)epigallocatechin-3-gallate inhibit hypoxia- and serum-induced HIF-1alpha protein accumulation and VEGF expression in human cervical carcinoma and hepatoma cells
    • Zhang Q., Tang X., Lu Q., Zhang Z., Rao J., Le A.D. Green tea extract and (-)epigallocatechin-3-gallate inhibit hypoxia- and serum-induced HIF-1alpha protein accumulation and VEGF expression in human cervical carcinoma and hepatoma cells. Mol. Cancer Ther. 2006, 5:1227-1238.
    • (2006) Mol. Cancer Ther. , vol.5 , pp. 1227-1238
    • Zhang, Q.1    Tang, X.2    Lu, Q.3    Zhang, Z.4    Rao, J.5    Le, A.D.6
  • 199
    • 33846188098 scopus 로고    scopus 로고
    • MicroRNAs as oncogenes and tumor suppressors
    • Zhang B., Pan X., Cobb G.P., Anderson T.A. MicroRNAs as oncogenes and tumor suppressors. Dev. Biol. 2007, 302:1-12.
    • (2007) Dev. Biol. , vol.302 , pp. 1-12
    • Zhang, B.1    Pan, X.2    Cobb, G.P.3    Anderson, T.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.