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Volumn 27, Issue 3, 2009, Pages 233-240

Silymarin attenuated mast cell recruitment thereby decreased the expressions of matrix metalloproteinases-2 and 9 in rat liver carcinogenesis

Author keywords

Hepatocellular carcinoma; Mast cell; MMP 2; MMP 9; N Nitrosodiethylamine; Silymarin

Indexed keywords

DIETHYLNITROSAMINE; GELATINASE A; GELATINASE B; SILYMARIN;

EID: 64649086559     PISSN: 01676997     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10637-008-9163-y     Document Type: Article
Times cited : (36)

References (46)
  • 2
    • 0033545541 scopus 로고    scopus 로고
    • Rising incidence of hepatocellular carcinoma in the United States
    • HB El-Serag AC Mason 1999 Rising incidence of hepatocellular carcinoma in the United States N Engl J Med 340 745 750
    • (1999) N Engl J Med , vol.340 , pp. 745-750
    • El-Serag, H.B.1    Mason, A.C.2
  • 3
    • 0035200712 scopus 로고    scopus 로고
    • Trends in survival of patients with hepatocellular carcinoma between 1977 and 1996 in the United States
    • HB El-Serag AC Mason C Key 2001 Trends in survival of patients with hepatocellular carcinoma between 1977 and 1996 in the United States Hepatology 33 62 65
    • (2001) Hepatology , vol.33 , pp. 62-65
    • El-Serag, H.B.1    Mason, A.C.2    Key, C.3
  • 4
    • 0030778910 scopus 로고    scopus 로고
    • Approaches to cancer prevention based on an understanding of N-nitrosamine carcinogenesis
    • SS Hecht 1997 Approaches to cancer prevention based on an understanding of N-nitrosamine carcinogenesis Proc Soc Exp Biol Med 216 2 181 191
    • (1997) Proc Soc Exp Biol Med , vol.216 , Issue.2 , pp. 181-191
    • Hecht, S.S.1
  • 5
    • 0017610865 scopus 로고
    • Formation in vivo of volatile N-nitrosamines in man after ingestion of cooked bacon and spinach
    • DH Fine R Ross DP Rounbehler A Silvergleid L Song 1977 Formation in vivo of volatile N-nitrosamines in man after ingestion of cooked bacon and spinach Nature 265 753 755
    • (1977) Nature , vol.265 , pp. 753-755
    • Fine, D.H.1    Ross, R.2    Rounbehler, D.P.3    Silvergleid, A.4    Song, L.5
  • 6
    • 0032717556 scopus 로고    scopus 로고
    • Tissue distribution of silibinin, the major active constituent of silymarin, in mice and its association with enhancement of phase II enzymes: Implications in cancer chemoprevention
    • J Zhao R Agarwal 1999 Tissue distribution of silibinin, the major active constituent of silymarin, in mice and its association with enhancement of phase II enzymes: implications in cancer chemoprevention Carcinogenesis 20 11 2101 2108
    • (1999) Carcinogenesis , vol.20 , Issue.11 , pp. 2101-2108
    • Zhao, J.1    Agarwal, R.2
  • 7
    • 27644469442 scopus 로고    scopus 로고
    • Dietary supplementation with silymarin inhibits 3,2¢-dimethyl-4- aminobiphenyl-induced prostate carcinogenesis in male F344 rats
    • H Kohno R Suzuki S Sugie H Tsuda T Tanaka 2005 Dietary supplementation with silymarin inhibits 3,2¢-dimethyl-4-aminobiphenyl-induced prostate carcinogenesis in male F344 rats Clin Cancer Res 11 13 4962 4967
    • (2005) Clin Cancer Res , vol.11 , Issue.13 , pp. 4962-4967
    • Kohno, H.1    Suzuki, R.2    Sugie, S.3    Tsuda, H.4    Tanaka, T.5
  • 9
    • 35348879054 scopus 로고    scopus 로고
    • Silymarin and epithelial cancer chemoprevention: How close are we to bedside?
    • M Kaur R Agarwal 2007 Silymarin and epithelial cancer chemoprevention: how close are we to bedside? Toxicol Appl Pharmacol 224 3 350 359
    • (2007) Toxicol Appl Pharmacol , vol.224 , Issue.3 , pp. 350-359
    • Kaur, M.1    Agarwal, R.2
  • 10
    • 33646828371 scopus 로고    scopus 로고
    • Suppression of N-nitrosodiethylamine induced hepatocarcinogenesis by silymarin in rats
    • G Ramakrishnan HR Raghavendran R Vinodhkumar T Devaki 2006 Suppression of N-nitrosodiethylamine induced hepatocarcinogenesis by silymarin in rats Chem Biol Interact 161 2 104 114
    • (2006) Chem Biol Interact , vol.161 , Issue.2 , pp. 104-114
    • Ramakrishnan, G.1    Raghavendran, H.R.2    Vinodhkumar, R.3    Devaki, T.4
  • 11
    • 34248169275 scopus 로고    scopus 로고
    • Effect of silymarin on N-nitrosodiethylamine induced hepatocarcinogenesis in rats
    • G Ramakrishnan TA Augustine S Jagan R Vinodhkumar T Devaki 2007 Effect of silymarin on N-nitrosodiethylamine induced hepatocarcinogenesis in rats Exp Oncol 29 1 39 44
    • (2007) Exp Oncol , vol.29 , Issue.1 , pp. 39-44
    • Ramakrishnan, G.1    Augustine, T.A.2    Jagan, S.3    Vinodhkumar, R.4    Devaki, T.5
  • 12
    • 0032727651 scopus 로고    scopus 로고
    • Inhibition of human carcinoma cell growth and DNA synthesis by silibinin, an active constituent of milk thistle: Comparison with silymarin
    • N Bhatia J Zhao DM Wolf R Agarwal 1999 Inhibition of human carcinoma cell growth and DNA synthesis by silibinin, an active constituent of milk thistle: comparison with silymarin Cancer Lett 147 77 84
    • (1999) Cancer Lett , vol.147 , pp. 77-84
    • Bhatia, N.1    Zhao, J.2    Wolf, D.M.3    Agarwal, R.4
  • 13
    • 14844334439 scopus 로고    scopus 로고
    • Silymarin and skin cancer prevention: Anti-inflammatory, antioxidant and immunomodulatory effects
    • SK Katiyar 2005 Silymarin and skin cancer prevention: anti-inflammatory, antioxidant and immunomodulatory effects Int J Oncol 26 169 176
    • (2005) Int J Oncol , vol.26 , pp. 169-176
    • Katiyar, S.K.1
  • 14
    • 0027683226 scopus 로고
    • Structural biochemistry and activation of matrix metalloproteinases
    • DE Kleiner WG Stetler-Stevenson 1993 Structural biochemistry and activation of matrix metalloproteinases Curr Opin Cell Biol 5 891 897
    • (1993) Curr Opin Cell Biol , vol.5 , pp. 891-897
    • Kleiner, D.E.1    Stetler-Stevenson, W.G.2
  • 15
    • 34547950952 scopus 로고    scopus 로고
    • Action of antiproteases on pancreatic cancer cells
    • Y Uchima T Sawada K Hirakawa 2007 Action of antiproteases on pancreatic cancer cells JOP 8 4 Suppl 479 487
    • (2007) JOP , vol.8 , Issue.4 SUPPL. , pp. 479-487
    • Uchima, Y.1    Sawada, T.2    Hirakawa, K.3
  • 16
    • 0033617532 scopus 로고    scopus 로고
    • Effects of angiogenesis inhibitors on multistage carcinogenesis in mice
    • G Bergers K Javaherian K Lo J Folkman D Hanahan 1999 Effects of angiogenesis inhibitors on multistage carcinogenesis in mice Science 284 808 812
    • (1999) Science , vol.284 , pp. 808-812
    • Bergers, G.1    Javaherian, K.2    Lo, K.3    Folkman, J.4    Hanahan, D.5
  • 17
    • 0037192458 scopus 로고    scopus 로고
    • Matrix metalloproteinase inhibitors and cancer: Trials and tribulations
    • ML Coussens B Fingleton LM Matrisian 2002 Matrix metalloproteinase inhibitors and cancer: trials and tribulations Science 295 2387 2392
    • (2002) Science , vol.295 , pp. 2387-2392
    • Coussens, M.L.1    Fingleton, B.2    Matrisian, L.M.3
  • 20
    • 25144474110 scopus 로고    scopus 로고
    • Low-dose irradiation promotes tissue revascularization through VEGF release from mast cells and MMP-9-mediated progenitor cell mobilization
    • B Heissig S Rafii H Akiyama Y Ohki Y Sato T Rafael 2005 Low-dose irradiation promotes tissue revascularization through VEGF release from mast cells and MMP-9-mediated progenitor cell mobilization J Exp Med 202 6 739 750
    • (2005) J Exp Med , vol.202 , Issue.6 , pp. 739-750
    • Heissig, B.1    Rafii, S.2    Akiyama, H.3    Ohki, Y.4    Sato, Y.5    Rafael, T.6
  • 22
    • 0042754636 scopus 로고    scopus 로고
    • Microvessel density, mast cell density and thymidine phosphorylase expression in oral squamous carcinoma
    • G Ranieri A Labriola G Achille G Florio AF Zito L Grammatica 2002 Microvessel density, mast cell density and thymidine phosphorylase expression in oral squamous carcinoma Int J Oncol 21 6 1317 1323
    • (2002) Int J Oncol , vol.21 , Issue.6 , pp. 1317-1323
    • Ranieri, G.1    Labriola, A.2    Achille, G.3    Florio, G.4    Zito, A.F.5    Grammatica, L.6
  • 23
    • 31344466042 scopus 로고    scopus 로고
    • Significance and relationship between infiltrating inflammatory cell and tumor angiogenesis in hepatocellular carcinoma tissues
    • SH Peng H Deng J Yang PP Xie C Li H Li 2005 Significance and relationship between infiltrating inflammatory cell and tumor angiogenesis in hepatocellular carcinoma tissues World J Gastroenterol 11 41 6521 6524
    • (2005) World J Gastroenterol , vol.11 , Issue.41 , pp. 6521-6524
    • Peng, S.H.1    Deng, H.2    Yang, J.3    Xie, P.P.4    Li, C.5    Li, H.6
  • 26
    • 0030024349 scopus 로고    scopus 로고
    • Identification of a committed precursor for the mast cell lineage
    • HR Rodewald M Dessing AM Dvorak SJ Galli 1996 Identification of a committed precursor for the mast cell lineage Science 271 818 822
    • (1996) Science , vol.271 , pp. 818-822
    • Rodewald, H.R.1    Dessing, M.2    Dvorak, A.M.3    Galli, S.J.4
  • 27
    • 39149102867 scopus 로고    scopus 로고
    • The significance and relationship between mast cells and tumour angiogenesis in non-small cell lung carcinoma
    • E Dundar U Oner BC Peker M Metintas S Isiksoy G Ak 2008 The significance and relationship between mast cells and tumour angiogenesis in non-small cell lung carcinoma J Int Med Res 36 1 88 95
    • (2008) J Int Med Res , vol.36 , Issue.1 , pp. 88-95
    • Dundar, E.1    Oner, U.2    Peker, B.C.3    Metintas, M.4    Isiksoy, S.5    Ak, G.6
  • 28
    • 37249059874 scopus 로고    scopus 로고
    • Stromal mast cells in invasive breast cancer are a marker of favourable prognosis: A study of 4,444 cases
    • AB Rajput DA Turbin MC Cheang DK Voduc S Leung KA Gelmon 2008 Stromal mast cells in invasive breast cancer are a marker of favourable prognosis: a study of 4,444 cases Breast Cancer Res Treat 107 2 249 257
    • (2008) Breast Cancer Res Treat , vol.107 , Issue.2 , pp. 249-257
    • Rajput, A.B.1    Turbin, D.A.2    Cheang, M.C.3    Voduc, D.K.4    Leung, S.5    Gelmon, K.A.6
  • 30
    • 0029856415 scopus 로고    scopus 로고
    • Effect of silymarin on different acute inflammation models and on leukocyte migration
    • R DeLaPuerta E Martinez L Bravo MC Ahumada 1996 Effect of silymarin on different acute inflammation models and on leukocyte migration J Pharm Pharmacol 48 9 968 970
    • (1996) J Pharm Pharmacol , vol.48 , Issue.9 , pp. 968-970
    • Delapuerta, R.1    Martinez, E.2    Bravo, L.3    Ahumada, M.C.4
  • 31
    • 44449096507 scopus 로고    scopus 로고
    • Silymarin downregulates COX-2 expression and attenuates hyperlipidaemia during NDEA induced rat hepatocellular carcinoma
    • G Ramakrishnan CM Elinos-Baez S Jagan TA Augustine S Kamaraj P Anandakumar 2008 Silymarin downregulates COX-2 expression and attenuates hyperlipidaemia during NDEA induced rat hepatocellular carcinoma Mol Cell Biochem 313 1-2 53 61
    • (2008) Mol Cell Biochem , vol.313 , Issue.12 , pp. 53-61
    • Ramakrishnan, G.1    Elinos-Baez, C.M.2    Jagan, S.3    Augustine, T.A.4    Kamaraj, S.5    Anandakumar, P.6
  • 32
    • 0034843656 scopus 로고    scopus 로고
    • Antifibrotic effect of silymarin in rat secondary biliary fibrosis is mediated by downregulation of procollagen alpha1(I) and TIMP-1
    • JD Jia M Bauer JJ Cho M Ruehl S Milani G Boigk 2001 Antifibrotic effect of silymarin in rat secondary biliary fibrosis is mediated by downregulation of procollagen alpha1(I) and TIMP-1 J Hepatol 35 3 392 398
    • (2001) J Hepatol , vol.35 , Issue.3 , pp. 392-398
    • Jia, J.D.1    Bauer, M.2    Cho, J.J.3    Ruehl, M.4    Milani, S.5    Boigk, G.6
  • 33
    • 0034330445 scopus 로고    scopus 로고
    • Correlation study of TGF beta expression in diethylnitrosamine-induced rat liver cancer and mast cell in its vicinity
    • M Zheng Y Ruan Z Wu 2000 Correlation study of TGF beta expression in diethylnitrosamine-induced rat liver cancer and mast cell in its vicinity Zhonghua Zhong Liu Za Zhi 22 6 463 465
    • (2000) Zhonghua Zhong Liu Za Zhi , vol.22 , Issue.6 , pp. 463-465
    • Zheng, M.1    Ruan, Y.2    Wu, Z.3
  • 34
    • 15744388309 scopus 로고    scopus 로고
    • A key role for mast cell chymase in the activation of pro-matrix metalloprotease-9 and pro-matrix metalloprotease-2
    • E Tchnougounova A Lundequist I Fajardo J Winberg M Abrink G Pejler 2005 A key role for mast cell chymase in the activation of pro-matrix metalloprotease-9 and pro-matrix metalloprotease-2 J Biol Chem 280 10 9291 9296
    • (2005) J Biol Chem , vol.280 , Issue.10 , pp. 9291-9296
    • Tchnougounova, E.1    Lundequist, A.2    Fajardo, I.3    Winberg, J.4    Abrink, M.5    Pejler, G.6
  • 35
    • 0036782035 scopus 로고    scopus 로고
    • MMP-9 induction by vascular endothelial growth factor receptor-1 is involved in lung-specific metastasis
    • S Hiratsuka K Nakamura S Iwai M Murakami T Itoh H Kijima 2002 MMP-9 induction by vascular endothelial growth factor receptor-1 is involved in lung-specific metastasis Cancer Cell 2 4 289 300
    • (2002) Cancer Cell , vol.2 , Issue.4 , pp. 289-300
    • Hiratsuka, S.1    Nakamura, K.2    Iwai, S.3    Murakami, M.4    Itoh, T.5    Kijima, H.6
  • 36
    • 0036512208 scopus 로고    scopus 로고
    • New functions for the matrix metalloproteinases in cancer progression
    • M Egeblad Z Werb 2002 New functions for the matrix metalloproteinases in cancer progression Nat Rev Cancer 2 161 174
    • (2002) Nat Rev Cancer , vol.2 , pp. 161-174
    • Egeblad, M.1    Werb, Z.2
  • 37
    • 0019195010 scopus 로고
    • Metastatic potential correlates with enzymatic degradation of basement-membrane collagen
    • LA Liotta K Tryggvason S Garbisa I Hart CM Foltz S Shatic 1980 Metastatic potential correlates with enzymatic degradation of basement-membrane collagen Nature 284 67 68
    • (1980) Nature , vol.284 , pp. 67-68
    • Liotta, L.A.1    Tryggvason, K.2    Garbisa, S.3    Hart, I.4    Foltz, C.M.5    Shatic, S.6
  • 38
    • 0030576517 scopus 로고    scopus 로고
    • Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
    • D Hanahan J Folkman 1996 Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis Cell 86 353 364
    • (1996) Cell , vol.86 , pp. 353-364
    • Hanahan, D.1    Folkman, J.2
  • 39
    • 0033134622 scopus 로고    scopus 로고
    • Matrix metalloproteinases in angiogenesis: A moving target for therapeutic intervention
    • WG Stetler-Stevenson 1999 Matrix metalloproteinases in angiogenesis: a moving target for therapeutic intervention J Clin Invest 103 1237 1241
    • (1999) J Clin Invest , vol.103 , pp. 1237-1241
    • Stetler-Stevenson, W.G.1
  • 40
    • 31144442936 scopus 로고    scopus 로고
    • Mechanisms of pericyte recruitment in tumor angiogenesis: A new role for metalloproteinases
    • CF Chantrian P Henriet S Jodele H Emonard O Feron PJ Courtoy 2006 Mechanisms of pericyte recruitment in tumor angiogenesis: a new role for metalloproteinases Eur J Cancer 42 3 310 318
    • (2006) Eur J Cancer , vol.42 , Issue.3 , pp. 310-318
    • Chantrian, C.F.1    Henriet, P.2    Jodele, S.3    Emonard, H.4    Feron, O.5    Courtoy, P.J.6
  • 41
    • 0034721666 scopus 로고    scopus 로고
    • MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis
    • LM Coussens CL Tinkle D Hanahan Z Werb 2000 MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis Cell 103 481 490
    • (2000) Cell , vol.103 , pp. 481-490
    • Coussens, L.M.1    Tinkle, C.L.2    Hanahan, D.3    Werb, Z.4
  • 42
    • 0000391746 scopus 로고    scopus 로고
    • Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis
    • G Bergers R Brekken G [tmp] McMahon TH Vu T Itoh K Tamaki 2000 Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis Nat Cell Biol 2 737 744
    • (2000) Nat Cell Biol , vol.2 , pp. 737-744
    • Bergers, G.1    Brekken, R.2    McMahon, G.3    Vu, T.H.4    Itoh, T.5    Tamaki, K.6
  • 44
    • 33746932123 scopus 로고    scopus 로고
    • Human mast cell-derived gelatinase B (matrix metalloproteinase-9) is regulated by inflammatory cytokines: Role in cell migration
    • ND Girolamo I Indoh N Jackson D Wakefield HP [tmp] McNeil W Yan 2006 Human mast cell-derived gelatinase B (matrix metalloproteinase-9) is regulated by inflammatory cytokines: role in cell migration J Immunol 177 2638 2650
    • (2006) J Immunol , vol.177 , pp. 2638-2650
    • Girolamo, N.D.1    Indoh, I.2    Jackson, N.3    Wakefield, D.4    McNeil, H.P.5    Yan, W.6
  • 45
    • 0344441770 scopus 로고    scopus 로고
    • Matrix metalloproteinases (MMP), EMMPRIN (extracellular matrix metalloproteinase inducer) and mitogen-activated protein kinases (MAPK): Co-expression in metastatic serous ovarian carcinoma
    • B Davidson V Givant-Horwitz P Lazarovici B Risberg JM Nesland CG Trope 2003 Matrix metalloproteinases (MMP), EMMPRIN (extracellular matrix metalloproteinase inducer) and mitogen-activated protein kinases (MAPK): co-expression in metastatic serous ovarian carcinoma Clin Exp Metastasis 20 7 621 631
    • (2003) Clin Exp Metastasis , vol.20 , Issue.7 , pp. 621-631
    • Davidson, B.1    Givant-Horwitz, V.2    Lazarovici, P.3    Risberg, B.4    Nesland, J.M.5    Trope, C.G.6
  • 46
    • 0036210452 scopus 로고    scopus 로고
    • Silymarin inhibits growth and causes regression of established skin tumors in SENCAR mice via modulation of mitogen-activated protein kinases and induction of apoptosis
    • RP Singh AK Tyagi J Zhao R Agarwal 2002 Silymarin inhibits growth and causes regression of established skin tumors in SENCAR mice via modulation of mitogen-activated protein kinases and induction of apoptosis Carcinogenesis 23 3 499 510
    • (2002) Carcinogenesis , vol.23 , Issue.3 , pp. 499-510
    • Singh, R.P.1    Tyagi, A.K.2    Zhao, J.3    Agarwal, R.4


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