Dietary supplementation of curcumin enhances antioxidant and phase II metabolizing enzymes in ddY male mice: Possible role in protection against chemical carcinogenesis and toxicity

Pharmacology and Toxicology

Volumn 92, Issue 1, 2003, Pages 33-38

  Iqbal, Mohammad ^a   Sharma, Som Datta ^b   Okazaki, Yasumasa ^a   Fujisawa, Masayoshi ^a   Okada, Shigeru ^a  

^a OKAYAMA UNIVERSITY MEDICAL SCHOOL   (Japan)

^b HAMDARD UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; CARCINOGEN; CATALASE; ENZYME; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE);

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CANCER PREVENTION; CHEMICAL CARCINOGENESIS; CONTROLLED STUDY; DETOXIFICATION; DIET SUPPLEMENTATION; ENZYME ACTIVITY; ENZYME INDUCTION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTICARCINOGENIC AGENTS; ANTIOXIDANTS; CARCINOGENS; CATALASE; CURCUMIN; DIETARY SUPPLEMENTS; GLUCOSEPHOSPHATE DEHYDROGENASE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; KIDNEY; LIVER; MALE; MICE;

ANIMALIA; CURCUMA LONGA;

EID: 0345074085     PISSN: 09019928     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0773.2003.920106.x     Document Type: Article

References (48)

1. Ammon, H. P. T. & M. A. Wahl: Pharmacology of Curcuma longa. Planta Med. 1991, 57, 1-7.
2. Ansar, S., M. Iqbal & M. Athar: Nordihydroguairetic acid is a potent inhibitor of ferric nitrilotriacetate mediated hepatic and renal toxicity, and renal tumor promotion, in mice. Carcinogenesis 1999, 20, 599-606.
3. Araujo, C. C. & L. L. Leon: Biological activities of Curcuma longa L. Mem. Inst. Oswaldo Cruz. 2001, 96, 723-730.
4. Athar, M. & M. Iqbal: Ferric nitrilotriacetate promote N-diethynitrosamine-induced renal tumorigenesis in the rat: Implications for the involvement of oxidative stress. Carcinogenesis 1998, 19, 1133-1139.
5. Azuine, M. A. & S. V. Bhide: Chemopreventive effect of turmeric against stomach and skin tumors induced by chemical carcinogenesis in swiss mice. Nutr. Cancer 1992, 17, 77-83.
6. Benson, A. M., M. J. Hunkler & P.Talalay: Increase of NADPH: Quinone reductase activity by dietary antioxidant: Possible role in protection against carcinogenesis and toxicity. Proc. Natl. Acad. Sci. USA 1980, 77, 5116-5620.
7. Boone, C. W., G. J. Kelloff & W. F. Malane: Identification of candidate as cancer chemopreventive agents and their evaluation in animal models and human clinical trials: a review. Cancer Res. 1990, 50, 2-9.
8. Carlberg, I. & B. Mannervik: Glutathione reductase levels in rat brain. J. Biol. Chem. 1975, 250, 5475-5480.
9. Cavalieri, E. L., D. E. Stack, P. D. Devanesan, R. Todorovic, I. Dwivedy, S. Higginbotham, S. L. Johansson, K. D. Patil, M. L.Gross, J. K. Gooden, R. Ramanathan, R.L. Cerny & E. G. Rogan: Molecular origin of cancer: catechol estrogen-3,4-quinones as endogenous tumor initiator. Proc. Natl. Acad. Sci. USA 1997, 94, 10937-10942.
10. Claiborne, A.: Catalase activity. In: CRC Hand book of methods for oxygen radical research. Ed.: R. A. Green Wald. CRC Press, Boca Raton, FL, 1985 pp. 283-284.
11. Digiovanni, J.: Multistage carcinogenesis in mouse skin. Pharmacol. Therap. 1992, 54, 63-128.
12. Doll, R. & R, Peto: The cause of cancer: quantitative estimates of avoidable risks of cancer in United States today. J. Natl. Cancer Inst 1981, 66, 1191-1308.
13. Dorai, T., Y.C . Cao, B. Dorai, R. Buttyan & A. E. Katz: Therapeutic potential of curcumin in human prostate cancer. III. Curcumin inhibits, induces apoptosis, and inhibits angiogenesis of LNCaP prostate cancer cells in viva. Prostate 2001, 47, 293-303.
14. Goel, A., C. R. Boland & D. P. Chauhan: Specific inhibition of cyclooxygenase-2 (COX-2) expression by dietary curcumin in HT-29 human colon cancer cells. Cancer Lett. 2001, 172, 111-118.
15. Habig, W. H., M. J. Pabst & W. B. Jokoby: Glutathione S-transferase: The first enzymatic step in mercapturic acid formation. J. Biol. Chem. 1974, 249, 7130-7139.
16. Huang, M.-T., R. C. Smart, G.-Q. Wang & A. H. Conney: Inhibitory effect of curcumin, chlorogenic acid, caffeic acid, and ferulic acid on tumor promotion in mouse skin by 12-O-tetradecanoylphorbol-13-acetate. Cancer Res. 1988, 48, 5941-5946.
17. Huang, M.-T., T. Lysz, T. Ferraro, T. F. Abidi, J. D. Laskin & A. H. Conney: Inhibitory effects of curcumin on in vitro lipoxygenase and cyclooxygenase activities in mouse epidermis. Cancer Res. 1991, 51, 813-819.
18. Huang, M.-T., T. Lysz, T. Ferraro, T. F. Abidi, J. D. Laskin & A. H. Conney: Inhibitory effect of curcumin on tumor initiation by benzo(a)pyrene and 7,12-dimethybenz (a)anthracene. Carcinogenesis (Land.) 1992, 13, 2183-2186.
19. Huang, M.-T., W. Ma, Y.-R. Lou, T. Ferraro, K. Reuhl, H. Newmark & A. H. Conney: Inhibitory effect of dietary curcumin on gastrointestinal tumorigenesis in mice. Proc. Amer. Ass. Cancer Res. 1993, 34, 555.
20. Iqbal, M., U, Giri & M. Athar: Ferric nitrilotriacetate is a potent hepatic tumor promoter and acts through the generation of oxidative stress. Biochem. Biophys. Res. Commun. 1995, 212, 557-563.
21. Iqbal, M., S. D. Sharma, A. Rahman, P. Trikha & M. Athar: Evidence that ferric nitrilotriacetate mediates oxidative stress by down regulating DT-diaphorase activity: Implication for carcinogenesis. Cancer Lett. 1999, 141, 151-157.
22. Iqbal, M., H. Rezazadeh, S. Ansar & M. Athar (a): Tocopherol (vitamin E) ameliorates ferric nitrilotriacetate (Fe-NTA)-dependent renal proliferative response and toxicity: diminution of oxidative stress. Human Exp. Toxicol. 1998a, 17, 163-171.
23. Iqbal, M., S. D. Sharma, H. Rezazadeh, N. Hasan, M. Abdulla & M. Athar: Glutathione metabolizing enzymes and oxidative stress in ferric nitrilotriacetate mediated hepatic injury. Redox Report 1996, 2, 385-391.
24. Iqbal, M. & M. Athar: Attenuation of iron-nitrilotriacetate (FeNTA)-mediated renal oxidative stress, toxicity and hyperproliferative response by the prophylactic treatment of rats with garlic oil. Food & Chem. Toxicol. 1998b, 36, 485-495.
25. Kakar, S. S. & D. Roy: Curcumin inhibits TPA-induced expression of C-los, C-jun and C-myc proto-oncogenes messenger RNA in mouse skin. Cancer Lett. 1994, 87, 85-89.
26. Kelloff, G. J., C. W. Boone, W. E. Malone & V. E. Steele: Recent results in preclinical and clinical drug development of chemopreventive agents at the National Cancer Institute. In: Cancer chemoprevention. Eds.: L. W. Wattenberg, M. Lipkin, C. W. Boone & G. J. Kelloff. CRC Press, Boca Raton, FL, 1992, pp. 41-56.
27. Ketterer, B., K. H. Tan, D. J. Meyer & B. Coles: Glutathione transferases a possible role in the detoxification of DNA and lipid hydroperoxides. In: Glutathione S-transferase and carcinogenesis. Eds.: T. J. Mantle, C. B. Pickett, & J. D. HayesTaylor and Francis, New York, 1987, pp. 149-163.
28. Li, J. K. & S. Y. Lin-Shia: Mechanism of cancer chemoprevention by curcumin. Proc. Natl. Sci. Counc. Repub. China 2001, 25, 59-66.
29. Limtrakul, P. P., S. Anuchapreeda, S. Lipigomgoson & F. W. Dunni: Inhibition of carcinogen induced C-Ha-ras and C-fos protooncogenes expression by dietary curcumin. BMC Cancer 2001, 1, 1.
30. Mohandas, J., J. J. Marshall, G. G. Duggin, J. S. Horvath & D. Tiller: Differential distribution of glutathione and glutathione related enzymes in rabbit kidney: Possible implications in analgesic neuropathy. Cancer Res. 1984, 44, 5086-5091.
31. Monks, T., R. P. Hanzlik, G. M. Cohen, D. Ross & D. G. Graham: Quinone chemistry and toxicity. Toxicol. Appl. Pharmacol. 1992, 112, 2-16.
32. Mori, H., K. Niwa, Q. Zheng, Y. Yamada, K. Sakata & N. Yoshimi: Cell proliferation in cancer chemoprevention; effects of preventive agents on estrogen-related endometrial carcinogenesis model and on in vitro model in human colorectal cell. Mutat. Res. 2001, 480-481, 201-207.
33. Perchellet, J. & E. M. Perchellet: Antioxidants and multistage carcinogenesis in mouse skin. Free Radical Biol. Med. 1989, 7, 377-408.
34. Piper, T. J., S. S. Singhal, M. S. Salameh, R. T. Torman, Y. C. Awasthi & S. Awasthi: Mechanisms of anticarcinogenic properties of curcumin: the effect of curcumin on glutathione linked detoxification enzymes in rat liver. Int. J. Biochem. Cell Biol. 1998, 30, 445-456.
35. Piwocka, K., E. Jaruga, J. Skierski, I. Gradzka & E. Sikora: Effect of glutathione depletion on caspase-3 independent apoptosis pathway induced by curcumin in Jurkat cells. Free Radical Biol. Med. 2001, 31, 670-678.
36. Raes, M., C. Michies & J. Remale: Comparative study of the enzymatic defense system against oxygen-derived free radicals: the key role of glutathione peroxidase. Free Radical Biol. Med. 1987, 3, 3-7.
37. Rao, C. V., B. Simi & B. S. Reddy: Inhibition by dietary curcumin of azoxymethane induced ornithine decarboxylase, tyrosine protein kinase, arachidonic acid metabolism and aberrant crypt foci formation in rat colon. Carcinogenesis (Lond.), 1993, 14, 2219-2225.
38. Rao, C. V. & B. S. Reddy: Modulating effect of amount and types of dietary fats on ornithine decarboxylase, tyrosine protein kinase and prostaglandin's production during colon carcinogenesis in male F344 rats. Carcinogenesis (Lond.,) 1993, 14, 1327-1333.
39. Reiners, J. J. Jr., G. Thai, I. Rupp & A. R. Cantu: Assesment of the antioxidant/prooxidant status of murine skin following topical treatment with 12-O-tetradecanoylphorbol-13-acetate and throughout ontogeny of skin cancer. Part I: quantitation of superoxide dismutase, catalase, glutathione peroxidase and xanthine oxidase. Carcinogenesis, 1991, 12, 2337-2343.
40. Satoskar, R. R., S. J. Shah & S. G. Shenoy: Evaluation of anti-inflammatory property of curcumin (diferuloyl methane) in patients with postoperative inflammation. Intl. J. Clin. Pharmacol. Ther. Toxicol. 1986, 24, 651-654.
41. Sharma, O. P.: Antioxidant activity of curcumin and related compound. Biochem. Pharmacol. 1976, 25, 1811-1812.
42. Smith, W. A., J. W. Freeman & R. C. Gupta: Effect of chemopreventive agents on DNA adduction induced by the potent mammary carcinogen dibenzo[a,I] pyrene in human breast cells MCF-7. Murat. Res. 2001, 480-481, 97-108.
43. Sun, Y.: Free radicals, antioxidant enzymes, and carcinogenesis. Free Radical Biol. Med. 1990, 8, 583-599.
44. Surh, Y. J., K. S. Chun, H. H. Cha, S. S. Han, Y. S. Keum, K. K. Park & S. S. Lee: Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: down-regulation of COX-2 and iNOS through suppression of NF-Kappa B activation. Murat. Res. 2001, 480-481, 243-268.
45. Wattenberg, L. W. & J. B. Coccia: Inhibition of 4-(methynitrosamino)-1-(3-pyridoyl)-1-butanone carcinogenesis in mice by d-limonene and citrus fruit oils. Carcinogenesis 1990, 12, 115-117.
46. Wattenberg, L. W.: Chemoprevention of cancer. Cancer Res. 1985, 45, 1-8.
47. Wattenberg, L. W.: Chemoprevention of cancer by naturally occurring and synthetic compounds. In: Cancer chemoprevention. Eds.: M. Wattenberg, C. W. Lipkin, C. W. Boone, and G. J. Kelloff FL, CRC Press, Boca Raton, 1992, pp. 19-39.
48. Zaheer, N., K. K. Tiwari & P. S. Krishnan: Exposure and solubilization of hepatic mitochondrial shunt dehydrogenase. Arch. Biochem. Biophys. 1965, 109, 646-648.