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Volumn 30, Issue 7, 2009, Pages 1234-1242

Pterostilbene inhibited tumor invasion via suppressing multiple signal transduction pathways in human hepatocellular carcinoma cells

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMETASTATIC AGENT; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHATIDYLINOSITOL 3 KINASE; PTEROSTILBENE; STRESS ACTIVATED PROTEIN KINASE 1; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG; VASCULOTROPIN;

EID: 67650105291     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgp121     Document Type: Article
Times cited : (137)

References (43)
  • 1
    • 40549119870 scopus 로고    scopus 로고
    • Pharmacometrics of pterostilbene: Preclinical pharmacokinetics and metabolism, anticancer, antiinflammatory, antioxidant and analgesic activity
    • Remsberg,C.M. et al. (2008) Pharmacometrics of pterostilbene: preclinical pharmacokinetics and metabolism, anticancer, antiinflammatory, antioxidant and analgesic activity. Phytother. Res. 22, 169-179.
    • (2008) Phytother. Res , vol.22 , pp. 169-179
    • Remsberg, C.M.1
  • 2
    • 51649121802 scopus 로고    scopus 로고
    • Pterostilbene suppressed lipopolysaccharide-induced up-expression of iNOS and COX-2 in murine macrophages
    • Pan,M.H. et al. (2008) Pterostilbene suppressed lipopolysaccharide-induced up-expression of iNOS and COX-2 in murine macrophages. J. Agric. Food Chem., 56, 7502-7509.
    • (2008) J. Agric. Food Chem , vol.56 , pp. 7502-7509
    • Pan, M.H.1
  • 3
    • 0034517138 scopus 로고    scopus 로고
    • Hepatocellular carcinoma
    • Bergsland,E.K. et al. (2000) Hepatocellular carcinoma. Curr. Opin. Oncol., 12, 357-361.
    • (2000) Curr. Opin. Oncol , vol.12 , pp. 357-361
    • Bergsland, E.K.1
  • 4
    • 0027954591 scopus 로고
    • Prognostic factors of hepatocellular carcinoma in patients undergoing hepatic resection
    • Izumi,R. et al. (1994) Prognostic factors of hepatocellular carcinoma in patients undergoing hepatic resection. Gastroenterology 106, 720-727.
    • (1994) Gastroenterology , vol.106 , pp. 720-727
    • Izumi, R.1
  • 5
    • 33750458019 scopus 로고    scopus 로고
    • Matrix metalloproteinase inhibitor RO 28-2653 decreases liver metastasis by reduction of MMP-2 and MMP-9 concentration in BOP-induced ductal pancreatic cancer in Syrian Hamsters: Inhibition of matrix metalloproteinases in pancreatic cancer
    • Kilian,M. et al. (2006) Matrix metalloproteinase inhibitor RO 28-2653 decreases liver metastasis by reduction of MMP-2 and MMP-9 concentration in BOP-induced ductal pancreatic cancer in Syrian Hamsters: Inhibition of matrix metalloproteinases in pancreatic cancer. Prostaglandins Leukot. Essent. Fatty Acids, 75, 429-434.
    • (2006) Prostaglandins Leukot. Essent. Fatty Acids , vol.75 , pp. 429-434
    • Kilian, M.1
  • 6
    • 0033915538 scopus 로고    scopus 로고
    • The significance of MMP-1 and MMP-2 in peritoneal disseminated metastasis of gastric cancer
    • Mizutani,K. et al. (2000) The significance of MMP-1 and MMP-2 in peritoneal disseminated metastasis of gastric cancer. Surg. Today, 30, 614-621.
    • (2000) Surg. Today , vol.30 , pp. 614-621
    • Mizutani, K.1
  • 7
    • 0033988558 scopus 로고    scopus 로고
    • The relation of gelatinase (MMP-2 and -9) expression with distant site metastasis and tumour aggressiveness in colorectal cancer
    • Gullu,I.H. et al. (2000) The relation of gelatinase (MMP-2 and -9) expression with distant site metastasis and tumour aggressiveness in colorectal cancer. Br. J. Cancer, 82, 249.
    • (2000) Br. J. Cancer , vol.82 , pp. 249
    • Gullu, I.H.1
  • 8
    • 33847683870 scopus 로고    scopus 로고
    • Regulation of matrix metalloproteinase gene expression
    • Yan,C. et al. (2007) Regulation of matrix metalloproteinase gene expression. J. Cell. Physiol., 211, 19-26.
    • (2007) J. Cell. Physiol , vol.211 , pp. 19-26
    • Yan, C.1
  • 9
    • 56749185606 scopus 로고    scopus 로고
    • Extracellular matrix metalloproteinase inducer (EMMPRIN) and matrix metalloproteinases (MMPs) as regulators of tumor-host interaction in a spontaneous metastasis model in rats
    • Donadio,A.C. et al. (2008) Extracellular matrix metalloproteinase inducer (EMMPRIN) and matrix metalloproteinases (MMPs) as regulators of tumor-host interaction in a spontaneous metastasis model in rats. Histochem. Cell Biol., 130, 1155-1164.
    • (2008) Histochem. Cell Biol , vol.130 , pp. 1155-1164
    • Donadio, A.C.1
  • 10
    • 40649088574 scopus 로고    scopus 로고
    • Src kinase regulates metalloproteinase-9 secretion induced by type IV collagen in MCF-7 human breast cancer cells
    • Cortes-Reynosa,P. et al. (2008) Src kinase regulates metalloproteinase-9 secretion induced by type IV collagen in MCF-7 human breast cancer cells. Matrix Biol., 27, 220-231.
    • (2008) Matrix Biol , vol.27 , pp. 220-231
    • Cortes-Reynosa, P.1
  • 11
    • 33744487384 scopus 로고    scopus 로고
    • Ets-1 is up-regulated together with its target gene products matrix metalloproteinase-2 and matrix metalloproteinase-9 in atypical and anaplastic meningiomas
    • Okuducu,A.F. et al. (2006) Ets-1 is up-regulated together with its target gene products matrix metalloproteinase-2 and matrix metalloproteinase-9 in atypical and anaplastic meningiomas. Histopathology, 48, 836-845.
    • (2006) Histopathology , vol.48 , pp. 836-845
    • Okuducu, A.F.1
  • 12
    • 35048835797 scopus 로고    scopus 로고
    • TNF-alpha and IL-1 beta-mediated regulation of MMP-9 and TIMP-1 in human glomerular mesangial cells
    • Nee,L. et al. (2007) TNF-alpha and IL-1 beta-mediated regulation of MMP-9 and TIMP-1 in human glomerular mesangial cells. Nephron. Exp. Nephrol., 107, e73-e86.
    • (2007) Nephron. Exp. Nephrol , vol.107
    • Nee, L.1
  • 13
    • 35148897176 scopus 로고    scopus 로고
    • Positive feedback regulation between MMP-9 and VEGF in human RPE cells
    • Hollborn,M. et al. (2007) Positive feedback regulation between MMP-9 and VEGF in human RPE cells. Invest. Ophthalmol. Vis. Sci., 48, 4360-4367.
    • (2007) Invest. Ophthalmol. Vis. Sci , vol.48 , pp. 4360-4367
    • Hollborn, M.1
  • 14
    • 49649098028 scopus 로고    scopus 로고
    • Matrix metalloproteinase 9 is a mediator of epidermal growth factor-dependent e-cadherin loss in ovarian carcinoma cells
    • Cowden Dahl,K.D. et al. (2008) Matrix metalloproteinase 9 is a mediator of epidermal growth factor-dependent e-cadherin loss in ovarian carcinoma cells. Cancer Res., 68, 4606-4613.
    • (2008) Cancer Res , vol.68 , pp. 4606-4613
    • Cowden Dahl, K.D.1
  • 15
    • 0036088906 scopus 로고    scopus 로고
    • Renal fibrosis. Extracellular matrix microenvironment regulates migratory behavior of activated tubular epithelial cells
    • Zeisberg,M. et al. (2002) Renal fibrosis. Extracellular matrix microenvironment regulates migratory behavior of activated tubular epithelial cells. Am. J. Pathol., 160, 2001-2008.
    • (2002) Am. J. Pathol , vol.160 , pp. 2001-2008
    • Zeisberg, M.1
  • 16
    • 37549026851 scopus 로고    scopus 로고
    • Suppression of PMA-induced tumor cell invasion by capillarisin via the inhibition of NF-kappaB-dependent MMP-9 expression
    • Lee,S.O. et al. (2008) Suppression of PMA-induced tumor cell invasion by capillarisin via the inhibition of NF-kappaB-dependent MMP-9 expression. Biochem. Biophys. Res. Commun., 366, 1019-1024.
    • (2008) Biochem. Biophys. Res. Commun , vol.366 , pp. 1019-1024
    • Lee, S.O.1
  • 17
    • 33846326821 scopus 로고    scopus 로고
    • Silibinin suppresses PMA-induced MMP-9 expression by blocking the AP-1 activation via MAPK signaling pathways in MCF-7 human breast carcinoma cells
    • Lee,S.O. et al. (2007) Silibinin suppresses PMA-induced MMP-9 expression by blocking the AP-1 activation via MAPK signaling pathways in MCF-7 human breast carcinoma cells. Biochem. Biophys. Res. Commun. 354, 165-171.
    • (2007) Biochem. Biophys. Res. Commun , vol.354 , pp. 165-171
    • Lee, S.O.1
  • 18
    • 34447096817 scopus 로고    scopus 로고
    • Ascofuranone suppresses PMA-mediated matrix metalloproteinase-9 gene activation through the Ras/Raf/MEK/ERK- and Ap1-dependent mechanisms
    • Cho,H.J. et al. (2007) Ascofuranone suppresses PMA-mediated matrix metalloproteinase-9 gene activation through the Ras/Raf/MEK/ERK- and Ap1-dependent mechanisms. Carcinogenesis, 28, 1104-1110.
    • (2007) Carcinogenesis , vol.28 , pp. 1104-1110
    • Cho, H.J.1
  • 19
    • 33947603008 scopus 로고    scopus 로고
    • Protein kinase C and other diacylglycerol effectors in cancer
    • Griner,E.M. et al. (2007) Protein kinase C and other diacylglycerol effectors in cancer. Nat. Rev. Cancer, 7, 281-294.
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 281-294
    • Griner, E.M.1
  • 20
    • 33846197451 scopus 로고    scopus 로고
    • Methyl-3-indolylacetate inhibits cancer cell invasion by targeting the MEK1/2-ERK1/2 signaling pathway
    • Zhang,S. et al. (2006) Methyl-3-indolylacetate inhibits cancer cell invasion by targeting the MEK1/2-ERK1/2 signaling pathway. Mol. Cancer Ther., 5, 3285-3293.
    • (2006) Mol. Cancer Ther , vol.5 , pp. 3285-3293
    • Zhang, S.1
  • 21
    • 7744229935 scopus 로고    scopus 로고
    • Hepatitis B viral HBx induces matrix metalloproteinase-9 gene expression through activation of ERK and PI-3K/ AKT pathways: Involvement of invasive potential
    • Chung,T.W. et al. (2004) Hepatitis B viral HBx induces matrix metalloproteinase-9 gene expression through activation of ERK and PI-3K/ AKT pathways: Involvement of invasive potential. FASEB J., 18 1123-1125.
    • (2004) FASEB J , vol.18 , pp. 1123-1125
    • Chung, T.W.1
  • 22
    • 0142212329 scopus 로고    scopus 로고
    • Regulation of matrix metalloproteinases: An overview
    • Chakraborti,S. et al. (2003) Regulation of matrix metalloproteinases: An overview. Mol. Cell. Biochem., 253, 269-285.
    • (2003) Mol. Cell. Biochem , vol.253 , pp. 269-285
    • Chakraborti, S.1
  • 23
    • 0035842316 scopus 로고    scopus 로고
    • The p38 SAPK pathway regulates the expression of the MMP-9 collagenase via AP-1-dependent promoter activation
    • Simon,C. et al. (2001) The p38 SAPK pathway regulates the expression of the MMP-9 collagenase via AP-1-dependent promoter activation. Exp. Cell Res., 271, 344-355.
    • (2001) Exp. Cell Res , vol.271 , pp. 344-355
    • Simon, C.1
  • 24
    • 54949091958 scopus 로고    scopus 로고
    • Amentoflavone inhibits experimental tumor metastasis through a regulatory mechanism involving MMP-2, MMP-9, prolyl hydroxylase, lysyl oxidase, VEGF, ERK-1, ERK-2, STAT-1, nm23 and cytokines in lung tissues of C57BL/6 mice
    • Guruvayoorappan,C. et al. (2008) Amentoflavone inhibits experimental tumor metastasis through a regulatory mechanism involving MMP-2, MMP-9, prolyl hydroxylase, lysyl oxidase, VEGF, ERK-1, ERK-2, STAT-1, nm23 and cytokines in lung tissues of C57BL/6 mice. Immunopharmacol. Immunotoxicol., 30, 711-727.
    • (2008) Immunopharmacol. Immunotoxicol , vol.30 , pp. 711-727
    • Guruvayoorappan, C.1
  • 25
    • 0348041947 scopus 로고    scopus 로고
    • Matrix metalloproteinase 2 and 9 activity in patients with colorectal cancer liver metastasis
    • Waas,E.T. et al. (2003) Matrix metalloproteinase 2 and 9 activity in patients with colorectal cancer liver metastasis. Br. J. Surg., 90, 1556-1564.
    • (2003) Br. J. Surg , vol.90 , pp. 1556-1564
    • Waas, E.T.1
  • 26
    • 0035913972 scopus 로고    scopus 로고
    • Matrix metalloproteinase-2 and -9 in bile as a marker of liver metastasis in colorectal cancer
    • Okada,N. et al. (2001) Matrix metalloproteinase-2 and -9 in bile as a marker of liver metastasis in colorectal cancer. Biochem. Biophys. Res. Commun., 288, 212-216.
    • (2001) Biochem. Biophys. Res. Commun , vol.288 , pp. 212-216
    • Okada, N.1
  • 27
    • 0037030688 scopus 로고    scopus 로고
    • Antineoplastic agents. 465. Structural modification of resveratrol: Sodium resverastatin phosphate
    • Pettit,G.R. et al. (2002) Antineoplastic agents. 465. Structural modification of resveratrol: Sodium resverastatin phosphate. J. Med. Chem., 45, 2534-2542.
    • (2002) J. Med. Chem , vol.45 , pp. 2534-2542
    • Pettit, G.R.1
  • 28
    • 0030843887 scopus 로고    scopus 로고
    • Functional coupling of endogenous serotonin (5-HT1B) and calcitonin (C1a) receptors in CHO cells to a cyclic AMP-responsive luciferase reporter gene
    • George,S.E. et al. (1997) Functional coupling of endogenous serotonin (5-HT1B) and calcitonin (C1a) receptors in CHO cells to a cyclic AMP-responsive luciferase reporter gene. J. Neurochem., 69, 1278-1285.
    • (1997) J. Neurochem , vol.69 , pp. 1278-1285
    • George, S.E.1
  • 29
    • 34347374313 scopus 로고    scopus 로고
    • EGF-R regulates MMP function in fibroblasts through MAPK and AP-1 pathways
    • Kajanne,R. et al. (2007) EGF-R regulates MMP function in fibroblasts through MAPK and AP-1 pathways. J. Cell. Physiol., 212, 489-497.
    • (2007) J. Cell. Physiol , vol.212 , pp. 489-497
    • Kajanne, R.1
  • 30
    • 38849178686 scopus 로고    scopus 로고
    • Lucidenic acid inhibits PMA-induced invasion of human hepatoma cells through inactivating MAPK/ERK signal transduction pathway and reducing binding activities of NF-kappaB and AP-1
    • Weng,C.J. et al. (2008) Lucidenic acid inhibits PMA-induced invasion of human hepatoma cells through inactivating MAPK/ERK signal transduction pathway and reducing binding activities of NF-kappaB and AP-1. Carcinogenesis, 29, 147-156.
    • (2008) Carcinogenesis , vol.29 , pp. 147-156
    • Weng, C.J.1
  • 31
    • 0020634260 scopus 로고
    • Protein kinase C as a possible receptor protein of tumor-promoting phorbol esters
    • Kikkawa,U. et al. (1983) Protein kinase C as a possible receptor protein of tumor-promoting phorbol esters. J. Biol. Chem., 258 11442-11445.
    • (1983) J. Biol. Chem , vol.258 , pp. 11442-11445
    • Kikkawa, U.1
  • 32
    • 61449206026 scopus 로고    scopus 로고
    • Role of PKCbeta in hepatocellular carcinoma cells migration and invasion in vitro: A potential therapeutic target
    • Guo,K. et al. (2008) Role of PKCbeta in hepatocellular carcinoma cells migration and invasion in vitro: A potential therapeutic target. Clin. Exp. Metastasis, 26, 189-195.
    • (2008) Clin. Exp. Metastasis , vol.26 , pp. 189-195
    • Guo, K.1
  • 33
    • 54449085540 scopus 로고    scopus 로고
    • Chemopreventive effects of natural dietary compounds on cancer development
    • Pan,M.H. et al. (2008) Chemopreventive effects of natural dietary compounds on cancer development. Chem. Soc. Rev., 37, 2558-2574.
    • (2008) Chem. Soc. Rev , vol.37 , pp. 2558-2574
    • Pan, M.H.1
  • 34
    • 33846286106 scopus 로고    scopus 로고
    • Pterostilbene, an active constituent of blueberries, suppresses aberrant crypt foci formation in the azoxymethane-induced colon carcinogenesis model in rats
    • Suh,N. et al. (2007) Pterostilbene, an active constituent of blueberries, suppresses aberrant crypt foci formation in the azoxymethane-induced colon carcinogenesis model in rats. Clin. Cancer Res., 13, 350-355.
    • (2007) Clin. Cancer Res , vol.13 , pp. 350-355
    • Suh, N.1
  • 35
    • 38949162199 scopus 로고    scopus 로고
    • Food bioactives, apoptosis, and cancer
    • Pan,M.H. et al. (2008) Food bioactives, apoptosis, and cancer. Mol. Nutr. Food Res., 52, 43-52.
    • (2008) Mol. Nutr. Food Res , vol.52 , pp. 43-52
    • Pan, M.H.1
  • 36
    • 34948835586 scopus 로고    scopus 로고
    • Pterostilbene induces apoptosis and cell cycle arrest in human gastric carcinoma cells
    • Pan,M.H. et al. (2007) Pterostilbene induces apoptosis and cell cycle arrest in human gastric carcinoma cells. J. Agric. Food Chem. 55, 7777-7785.
    • (2007) J. Agric. Food Chem , vol.55 , pp. 7777-7785
    • Pan, M.H.1
  • 37
    • 13444252223 scopus 로고    scopus 로고
    • Association between pterostilbene and quercetin inhibits metastatic activity of B16 melanoma
    • Ferrer,P. et al. (2005) Association between pterostilbene and quercetin inhibits metastatic activity of B16 melanoma. Neoplasia, 7, 37-47.
    • (2005) Neoplasia , vol.7 , pp. 37-47
    • Ferrer, P.1
  • 38
    • 34447625046 scopus 로고    scopus 로고
    • Akt activation induces epidermal hyperplasia and proliferation of epidermal progenitors
    • Murayama,K. et al. (2007) Akt activation induces epidermal hyperplasia and proliferation of epidermal progenitors. Oncogene, 26, 4882-4888.
    • (2007) Oncogene , vol.26 , pp. 4882-4888
    • Murayama, K.1
  • 39
    • 0029986938 scopus 로고    scopus 로고
    • Phosphoinositide kinases
    • Carpenter,C.L. et al. (1996) Phosphoinositide kinases. Curr. Opin. Cell Biol., 8, 153-158.
    • (1996) Curr. Opin. Cell Biol , vol.8 , pp. 153-158
    • Carpenter, C.L.1
  • 40
    • 7744221596 scopus 로고    scopus 로고
    • Novel and therapeutic effect of caffeic acid and caffeic acid phenyl ester on hepatocarcinoma cells: Complete regression of hepatoma growth and metastasis by dual mechanism
    • Chung,T.W. et al. (2004) Novel and therapeutic effect of caffeic acid and caffeic acid phenyl ester on hepatocarcinoma cells: Complete regression of hepatoma growth and metastasis by dual mechanism. FASEB J., 18, 1670-1681.
    • (2004) FASEB J , vol.18 , pp. 1670-1681
    • Chung, T.W.1
  • 41
    • 1842482424 scopus 로고    scopus 로고
    • Resveratrol inhibits phorbol myristate acetate-induced matrix metalloproteinase-9 expression by inhibiting JNK and PKC delta signal transduction
    • Woo,J.H. et al. (2004) Resveratrol inhibits phorbol myristate acetate-induced matrix metalloproteinase-9 expression by inhibiting JNK and PKC delta signal transduction. Oncogene, 23, 1845-1853.
    • (2004) Oncogene , vol.23 , pp. 1845-1853
    • Woo, J.H.1
  • 42
    • 46949111517 scopus 로고    scopus 로고
    • Curcumin decreases 12-O-tetradecanoylphorbol-13-acetate-induced protein kinase C translocation to modulate downstream targets in mouse skin
    • Garg,R. et al. (2008) Curcumin decreases 12-O-tetradecanoylphorbol-13-acetate-induced protein kinase C translocation to modulate downstream targets in mouse skin. Carcinogenesis, 29, 1249-1257.
    • (2008) Carcinogenesis , vol.29 , pp. 1249-1257
    • Garg, R.1
  • 43
    • 58249092965 scopus 로고    scopus 로고
    • Mechanisms of metastasis
    • Hunter,K.W. et al. (2008) Mechanisms of metastasis. Breast Cancer Res., 10 (suppl. 1), S2.
    • (2008) Breast Cancer Res , vol.10 , Issue.SUPPL. 1
    • Hunter, K.W.1


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