메뉴 건너뛰기




Volumn 26, Issue 2, 2012, Pages 140-155

Use of RNA interference to minimize ischemia reperfusion injury

Author keywords

[No Author keywords available]

Indexed keywords

BRG1 PROTEIN; COMPLEMENT FACTOR; DICER; DOUBLE STRANDED RNA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MICRORNA; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN P53; RIBOZYME; SINGLE STRANDED RNA; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR ALPHA;

EID: 84859007413     PISSN: 0955470X     EISSN: 15579816     Source Type: Journal    
DOI: 10.1016/j.trre.2011.03.001     Document Type: Review
Times cited : (13)

References (214)
  • 1
    • 23744445570 scopus 로고    scopus 로고
    • Beyond operational tolerance: effect of ischemic injury on development of chronic damage in renal grafts
    • Coulson M.T., Jablonski P., Howden B.O., Thomson N.M., Stein A.N. Beyond operational tolerance: effect of ischemic injury on development of chronic damage in renal grafts. Transplantation 2005, 80:353-361.
    • (2005) Transplantation , vol.80 , pp. 353-361
    • Coulson, M.T.1    Jablonski, P.2    Howden, B.O.3    Thomson, N.M.4    Stein, A.N.5
  • 3
    • 0030671040 scopus 로고    scopus 로고
    • Cold ischemic injury accelerates the progression to chronic rejection in a rat cardiac allograft model
    • Knight R.J., Dikman S., Liu H., Martinelli G.P. Cold ischemic injury accelerates the progression to chronic rejection in a rat cardiac allograft model. Transplantation 1997, 64:1102-1107.
    • (1997) Transplantation , vol.64 , pp. 1102-1107
    • Knight, R.J.1    Dikman, S.2    Liu, H.3    Martinelli, G.P.4
  • 4
    • 0030838681 scopus 로고    scopus 로고
    • Factors contributing to the development of chronic rejection in heterotopic rat heart transplantation
    • Schmid C., Heemann U., Tilney N.L. Factors contributing to the development of chronic rejection in heterotopic rat heart transplantation. Transplantation 1997, 64:222-228.
    • (1997) Transplantation , vol.64 , pp. 222-228
    • Schmid, C.1    Heemann, U.2    Tilney, N.L.3
  • 5
    • 33644782017 scopus 로고    scopus 로고
    • New cellular and molecular immune pathways in ischemia/reperfusion injury
    • Boros P., Bromberg J.S. New cellular and molecular immune pathways in ischemia/reperfusion injury. Am J Transplant 2006, 6:652-658.
    • (2006) Am J Transplant , vol.6 , pp. 652-658
    • Boros, P.1    Bromberg, J.S.2
  • 7
    • 0034614897 scopus 로고    scopus 로고
    • Consequences of cell death: exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells
    • Sauter B., Albert M.L., Francisco L., et al. Consequences of cell death: exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells. J Exp Med 2000, 191:423-434.
    • (2000) J Exp Med , vol.191 , pp. 423-434
    • Sauter, B.1    Albert, M.L.2    Francisco, L.3
  • 8
    • 58249089430 scopus 로고    scopus 로고
    • Machine perfusion or cold storage in deceased-donor kidney transplantation
    • Moers C., Smits J.M., Maathuis M.J., et al. Machine perfusion or cold storage in deceased-donor kidney transplantation. N Engl J Med 2009, 360:7-19.
    • (2009) N Engl J Med , vol.360 , pp. 7-19
    • Moers, C.1    Smits, J.M.2    Maathuis, M.J.3
  • 9
    • 77950296327 scopus 로고    scopus 로고
    • The role of toll-like receptors in renal diseases
    • Gluba A., Banach M., Hannam S., et al. The role of toll-like receptors in renal diseases. Nat Rev Nephrol 2010, 6:224-235.
    • (2010) Nat Rev Nephrol , vol.6 , pp. 224-235
    • Gluba, A.1    Banach, M.2    Hannam, S.3
  • 10
    • 65249148548 scopus 로고    scopus 로고
    • Signal transduction pathways involved in brain death-induced renal injury
    • Bouma H.R., Ploeg R.J., Schuurs T.A. Signal transduction pathways involved in brain death-induced renal injury. Am J Transplant 2009, 9:989-997.
    • (2009) Am J Transplant , vol.9 , pp. 989-997
    • Bouma, H.R.1    Ploeg, R.J.2    Schuurs, T.A.3
  • 11
    • 0021229867 scopus 로고
    • Inhibition of thymidine kinase gene expression by anti-sense RNA: a molecular approach to genetic analysis
    • Izant J.G., Weintraub H. Inhibition of thymidine kinase gene expression by anti-sense RNA: a molecular approach to genetic analysis. Cell 1984, 36:1007-1015.
    • (1984) Cell , vol.36 , pp. 1007-1015
    • Izant, J.G.1    Weintraub, H.2
  • 12
    • 0021894993 scopus 로고
    • Production of phenocopies by Krüppel antisense RNA injection into Drosophila embryos
    • Rosenberg U.B., Preiss A., Seifert E., Jäckle H., Knipple D.C. Production of phenocopies by Krüppel antisense RNA injection into Drosophila embryos. Nature 1985, 313:703-706.
    • (1985) Nature , vol.313 , pp. 703-706
    • Rosenberg, U.B.1    Preiss, A.2    Seifert, E.3    Jäckle, H.4    Knipple, D.C.5
  • 13
    • 0022441296 scopus 로고
    • Inhibition of gene expression in plant cells by expression of antisense RNA
    • Ecker J.R., Davis R.W. Inhibition of gene expression in plant cells by expression of antisense RNA. Proc Natl Acad Sci U S A 1986, 83:5372-5376.
    • (1986) Proc Natl Acad Sci U S A , vol.83 , pp. 5372-5376
    • Ecker, J.R.1    Davis, R.W.2
  • 14
    • 0021799874 scopus 로고
    • Constitutive and conditional suppression of exogenous and endogenous genes by anti-sense RNA
    • Izant J.G., Weintraub H. Constitutive and conditional suppression of exogenous and endogenous genes by anti-sense RNA. Science 1985, 229:345-352.
    • (1985) Science , vol.229 , pp. 345-352
    • Izant, J.G.1    Weintraub, H.2
  • 15
    • 0027751663 scopus 로고
    • The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • Lee R.C., Feinbaum R.L., Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 1993, 75:843-854.
    • (1993) Cell , vol.75 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 16
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire A., Xu S., Montgomery M.K., et al. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 1998, 391:806-811.
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3
  • 17
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • Elbashir S.M., Harborth J., Lendeckel W., et al. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 2001, 411:494-498.
    • (2001) Nature , vol.411 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3
  • 18
    • 0037711199 scopus 로고    scopus 로고
    • The dsRNA binding protein family: critical roles, diverse cellular functions
    • Saunders L.R., Barber G.N. The dsRNA binding protein family: critical roles, diverse cellular functions. FASEB J 2003, 17:961-983.
    • (2003) FASEB J , vol.17 , pp. 961-983
    • Saunders, L.R.1    Barber, G.N.2
  • 19
    • 0036245743 scopus 로고    scopus 로고
    • Expanding small RNA interference
    • Tuschl T. Expanding small RNA interference. Nat Biotechnol 2002, 20:446-448.
    • (2002) Nat Biotechnol , vol.20 , pp. 446-448
    • Tuschl, T.1
  • 20
    • 0034960390 scopus 로고    scopus 로고
    • Chemistry and biochemistry of 2',5'-oligoadenylate-based antisense strategy
    • Adah S.A., Bayly S.F., Cramer H., Silverman R.H., Torrence P.F. Chemistry and biochemistry of 2',5'-oligoadenylate-based antisense strategy. Curr Med Chem 2001, 8:1189-1212.
    • (2001) Curr Med Chem , vol.8 , pp. 1189-1212
    • Adah, S.A.1    Bayly, S.F.2    Cramer, H.3    Silverman, R.H.4    Torrence, P.F.5
  • 21
    • 0035800333 scopus 로고    scopus 로고
    • Signal integration via PKR
    • re2
    • Williams B.R. Signal integration via PKR. Sci STKE 2001, re2:1-10.
    • (2001) Sci STKE , pp. 1-10
    • Williams, B.R.1
  • 22
    • 33748069824 scopus 로고    scopus 로고
    • SiRNA and isRNA: two edges of one sword
    • Schlee M., Hornung V., Hartmann G. siRNA and isRNA: two edges of one sword. Mol Ther 2006, 14:463-470.
    • (2006) Mol Ther , vol.14 , pp. 463-470
    • Schlee, M.1    Hornung, V.2    Hartmann, G.3
  • 23
    • 0036753280 scopus 로고    scopus 로고
    • The long and short of siRNAs
    • Timmons L. The long and short of siRNAs. Mol Cell 2002, 10:435-437.
    • (2002) Mol Cell , vol.10 , pp. 435-437
    • Timmons, L.1
  • 24
    • 31544456413 scopus 로고    scopus 로고
    • Insights into the kinetics of siRNA-mediated gene silencing from live-cell and live-animal bioluminescent imaging
    • Bartlett D.W., Davis M.E. Insights into the kinetics of siRNA-mediated gene silencing from live-cell and live-animal bioluminescent imaging. Nucleic Acids Res 2006, 34:322-333.
    • (2006) Nucleic Acids Res , vol.34 , pp. 322-333
    • Bartlett, D.W.1    Davis, M.E.2
  • 25
    • 42449083822 scopus 로고    scopus 로고
    • Thymoglobulin and ischemia reperfusion injury in kidney and liver transplantation
    • Mehrabi A., Mood Z.A., Sadeghi M., et al. Thymoglobulin and ischemia reperfusion injury in kidney and liver transplantation. Nephrol Dial Transplant 2007, 22(Suppl 8):viii54-viii60.
    • (2007) Nephrol Dial Transplant , vol.22 , Issue.SUPPL. 8
    • Mehrabi, A.1    Mood, Z.A.2    Sadeghi, M.3
  • 26
    • 0036958769 scopus 로고    scopus 로고
    • Therapeutic potential of monoclonal antibodies in myocardial reperfusion injury
    • Nigam A., Kopecky S.L. Therapeutic potential of monoclonal antibodies in myocardial reperfusion injury. Am J Cardiovasc Drugs 2002, 2:367-376.
    • (2002) Am J Cardiovasc Drugs , vol.2 , pp. 367-376
    • Nigam, A.1    Kopecky, S.L.2
  • 27
    • 0033662341 scopus 로고    scopus 로고
    • Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development
    • Yeh W.C., Itie A., Elia A.J., et al. Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development. Immunity 2000, 12:633-642.
    • (2000) Immunity , vol.12 , pp. 633-642
    • Yeh, W.C.1    Itie, A.2    Elia, A.J.3
  • 28
    • 0035028575 scopus 로고    scopus 로고
    • Antisense oligonucleotides: promise and reality
    • Lebedeva I., Stein C.A. Antisense oligonucleotides: promise and reality. Annu Rev Pharmacol Toxicol 2001, 41:403-419.
    • (2001) Annu Rev Pharmacol Toxicol , vol.41 , pp. 403-419
    • Lebedeva, I.1    Stein, C.A.2
  • 29
    • 17144386185 scopus 로고    scopus 로고
    • Small interfering RNA for experimental cancer therapy
    • Tong A.W., Zhang Y., Nemunaitis J. Small interfering RNA for experimental cancer therapy. Curr Opin Mol Ther 2005, 7:114-124.
    • (2005) Curr Opin Mol Ther , vol.7 , pp. 114-124
    • Tong, A.W.1    Zhang, Y.2    Nemunaitis, J.3
  • 30
    • 0036385852 scopus 로고    scopus 로고
    • Comparison of antisense oligonucleotides and siRNAs in cell culture and in vivo
    • Bertrand J., Pottier M., Vekris A., et al. Comparison of antisense oligonucleotides and siRNAs in cell culture and in vivo. Biochem Biophys Res Commun 2002, 296:1000-1004.
    • (2002) Biochem Biophys Res Commun , vol.296 , pp. 1000-1004
    • Bertrand, J.1    Pottier, M.2    Vekris, A.3
  • 31
    • 0036742715 scopus 로고    scopus 로고
    • Applications of antisense and siRNAs during preclinical drug development
    • Thompson J.D. Applications of antisense and siRNAs during preclinical drug development. Drug Discov Today 2002, 7:912-917.
    • (2002) Drug Discov Today , vol.7 , pp. 912-917
    • Thompson, J.D.1
  • 32
    • 26844512817 scopus 로고    scopus 로고
    • Central administration of small interfering RNAs in rats: a comparison with antisense oligonucleotides
    • Senn C., Hangartner C., Moes S., Guerini D., Hofbauer K.G. Central administration of small interfering RNAs in rats: a comparison with antisense oligonucleotides. Eur J Pharmacol 2005, 522:30-37.
    • (2005) Eur J Pharmacol , vol.522 , pp. 30-37
    • Senn, C.1    Hangartner, C.2    Moes, S.3    Guerini, D.4    Hofbauer, K.G.5
  • 33
    • 0035955366 scopus 로고    scopus 로고
    • An extensive class of small RNAs in Caenorhabditis elegans
    • Lee R.C., Ambros V. An extensive class of small RNAs in Caenorhabditis elegans. Science 2001, 294:862-864.
    • (2001) Science , vol.294 , pp. 862-864
    • Lee, R.C.1    Ambros, V.2
  • 34
    • 0035955361 scopus 로고    scopus 로고
    • An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans
    • Lau N.C., Lim L.P., Weinstein E.G., Bartel D.P. An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science 2001, 294:858-862.
    • (2001) Science , vol.294 , pp. 858-862
    • Lau, N.C.1    Lim, L.P.2    Weinstein, E.G.3    Bartel, D.P.4
  • 35
    • 0035955374 scopus 로고    scopus 로고
    • Identification of novel genes coding for small expressed RNAs
    • Lagos-Quintana M., Rauhut R., Lendeckel W., Tuschl T. Identification of novel genes coding for small expressed RNAs. Science 2001, 294:853-858.
    • (2001) Science , vol.294 , pp. 853-858
    • Lagos-Quintana, M.1    Rauhut, R.2    Lendeckel, W.3    Tuschl, T.4
  • 36
    • 13944282215 scopus 로고    scopus 로고
    • Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs
    • Lim L.P., Lau N.C., Garrett-Engele P., et al. Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature 2005, 433:769-773.
    • (2005) Nature , vol.433 , pp. 769-773
    • Lim, L.P.1    Lau, N.C.2    Garrett-Engele, P.3
  • 37
    • 49949116902 scopus 로고    scopus 로고
    • The impact of microRNAs on protein output
    • Baek D., Villén J., Shin C., et al. The impact of microRNAs on protein output. Nature 2008, 455:64-71.
    • (2008) Nature , vol.455 , pp. 64-71
    • Baek, D.1    Villén, J.2    Shin, C.3
  • 38
    • 72949115517 scopus 로고    scopus 로고
    • Concordant regulation of translation and mRNA abundance for hundreds of targets of a human microRNA
    • Hendrickson D.G., Hogan D.J., McCullough H.L., et al. Concordant regulation of translation and mRNA abundance for hundreds of targets of a human microRNA. PLoS Biol 2009, 7:e1000238.
    • (2009) PLoS Biol , vol.7
    • Hendrickson, D.G.1    Hogan, D.J.2    McCullough, H.L.3
  • 39
    • 0348014774 scopus 로고    scopus 로고
    • Approaches for the sequence-specific knockdown of mRNA
    • Scherer L.J., Rossi J.J. Approaches for the sequence-specific knockdown of mRNA. Nat Biotechnol 2003, 21:1457-1465.
    • (2003) Nat Biotechnol , vol.21 , pp. 1457-1465
    • Scherer, L.J.1    Rossi, J.J.2
  • 40
    • 0024357988 scopus 로고
    • Specific gene suppression by engineered ribozymes in monkey cells
    • Cameron F.H., Jennings P.A. Specific gene suppression by engineered ribozymes in monkey cells. Proc Natl Acad Sci U S A 1989, 86:9139-9143.
    • (1989) Proc Natl Acad Sci U S A , vol.86 , pp. 9139-9143
    • Cameron, F.H.1    Jennings, P.A.2
  • 41
    • 0026714425 scopus 로고
    • Enzymes with new and highly specific endoribonuclease activities. 1988
    • Haseloff J., Gerlach W.L., Simple R.N.A. enzymes with new and highly specific endoribonuclease activities. 1988. Biotechnology 1992, 24:264-269.
    • (1992) Biotechnology , vol.24 , pp. 264-269
    • Haseloff, J.1    Gerlach, W.L.2    Simple, R.N.A.3
  • 43
    • 25144439064 scopus 로고    scopus 로고
    • Exon-specific RNA interference: a tool to determine the functional relevance of proteins encoded by alternatively spliced mRNAs
    • Celotto A.M., Lee J., Graveley B.R. Exon-specific RNA interference: a tool to determine the functional relevance of proteins encoded by alternatively spliced mRNAs. Methods Mol Biol 2005, 309:273-282.
    • (2005) Methods Mol Biol , vol.309 , pp. 273-282
    • Celotto, A.M.1    Lee, J.2    Graveley, B.R.3
  • 44
    • 0034737747 scopus 로고    scopus 로고
    • Genetic requirements for inheritance of RNAi in C. elegans
    • Grishok A., Tabara H., Mello C.C. Genetic requirements for inheritance of RNAi in C. elegans. Science 2000, 287:2494-2497.
    • (2000) Science , vol.287 , pp. 2494-2497
    • Grishok, A.1    Tabara, H.2    Mello, C.C.3
  • 46
    • 63849265378 scopus 로고    scopus 로고
    • A novel in vivo siRNA delivery system specifically targeting dendritic cells and silencing CD40 genes for immunomodulation
    • Zheng X., Vladau C., Zhang X., et al. A novel in vivo siRNA delivery system specifically targeting dendritic cells and silencing CD40 genes for immunomodulation. Blood 2009, 113:2646-2654.
    • (2009) Blood , vol.113 , pp. 2646-2654
    • Zheng, X.1    Vladau, C.2    Zhang, X.3
  • 47
    • 0035863097 scopus 로고    scopus 로고
    • RNA interference is mediated by 21- and 22-nucleotide RNAs
    • Elbashir S.M., Lendeckel W., Tuschl T. RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev 2001, 15:188-200.
    • (2001) Genes Dev , vol.15 , pp. 188-200
    • Elbashir, S.M.1    Lendeckel, W.2    Tuschl, T.3
  • 48
    • 1542336952 scopus 로고    scopus 로고
    • Rational siRNA design for RNA interference
    • Reynolds A., Leake D., Boese Q., et al. Rational siRNA design for RNA interference. Nat Biotechnol 2004, 22:326-330.
    • (2004) Nat Biotechnol , vol.22 , pp. 326-330
    • Reynolds, A.1    Leake, D.2    Boese, Q.3
  • 49
    • 0037804642 scopus 로고    scopus 로고
    • Whither RNAi?
    • Whither RNAi?. Nat Cell Biol 2003, 5:489-490.
    • (2003) Nat Cell Biol , vol.5 , pp. 489-490
  • 50
    • 68049131578 scopus 로고    scopus 로고
    • BRG1 increases transcription of proinflammatory genes in renal ischemia
    • Naito M., Zager R.A., Bomsztyk K. BRG1 increases transcription of proinflammatory genes in renal ischemia. J Am Soc Nephrol 2009, 20:1787-1796.
    • (2009) J Am Soc Nephrol , vol.20 , pp. 1787-1796
    • Naito, M.1    Zager, R.A.2    Bomsztyk, K.3
  • 51
    • 78449296513 scopus 로고    scopus 로고
    • Designing highly active siRNAs for therapeutic applications
    • Walton S.P., Wu M., Gredell J.A., Chan C. Designing highly active siRNAs for therapeutic applications. FEBS J 2010, 277:4806-4813.
    • (2010) FEBS J , vol.277 , pp. 4806-4813
    • Walton, S.P.1    Wu, M.2    Gredell, J.A.3    Chan, C.4
  • 52
    • 0035803583 scopus 로고    scopus 로고
    • Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate
    • Elbashir S.M., Martinez J., Patkaniowska A., Lendeckel W., Tuschl T. Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate. EMBO J 2001, 20:6877-6888.
    • (2001) EMBO J , vol.20 , pp. 6877-6888
    • Elbashir, S.M.1    Martinez, J.2    Patkaniowska, A.3    Lendeckel, W.4    Tuschl, T.5
  • 54
    • 0037686295 scopus 로고    scopus 로고
    • Killing the messenger: short RNAs that silence gene expression
    • Dykxhoorn D.M., Novina C.D., Sharp P.A. Killing the messenger: short RNAs that silence gene expression. Nat Rev Mol Cell Biol 2003, 4:457-467.
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 457-467
    • Dykxhoorn, D.M.1    Novina, C.D.2    Sharp, P.A.3
  • 55
    • 0037452812 scopus 로고    scopus 로고
    • A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA
    • Tiscornia G., Singer O., Ikawa M., Verma I.M. A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA. Proc Natl Acad Sci U S A 2003, 100:1844-1848.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 1844-1848
    • Tiscornia, G.1    Singer, O.2    Ikawa, M.3    Verma, I.M.4
  • 56
    • 0038606999 scopus 로고    scopus 로고
    • Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells
    • Czauderna F., Fechtner M., Dames S., et al. Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells. Nucleic Acids Res 2003, 31:2705-2716.
    • (2003) Nucleic Acids Res , vol.31 , pp. 2705-2716
    • Czauderna, F.1    Fechtner, M.2    Dames, S.3
  • 57
    • 36148933344 scopus 로고    scopus 로고
    • Chemically modified symmetric and asymmetric duplex RNAs: an enhanced stability to nuclease degradation and gene silencing effect
    • Kubo T., Zhelev Z., Ohba H., Bakalova R. Chemically modified symmetric and asymmetric duplex RNAs: an enhanced stability to nuclease degradation and gene silencing effect. Biochem Biophys Res Commun 2008, 365:54-61.
    • (2008) Biochem Biophys Res Commun , vol.365 , pp. 54-61
    • Kubo, T.1    Zhelev, Z.2    Ohba, H.3    Bakalova, R.4
  • 58
    • 29844452007 scopus 로고    scopus 로고
    • Small interfering RNAs containing full 2'-O-methylribonucleotide-modified sense strands display Argonaute2/eIF2C2-dependent activity
    • Kraynack B.A., Baker B.F. Small interfering RNAs containing full 2'-O-methylribonucleotide-modified sense strands display Argonaute2/eIF2C2-dependent activity. RNA 2006, 12:163-176.
    • (2006) RNA , vol.12 , pp. 163-176
    • Kraynack, B.A.1    Baker, B.F.2
  • 59
    • 33644620908 scopus 로고    scopus 로고
    • Chemical modification of siRNAs to improve serum stability without loss of efficacy.
    • Choung S., Kim Y.J., Kim S., Park H., Choi Y. Chemical modification of siRNAs to improve serum stability without loss of efficacy. Biochem Biophys Res Commun 2006, 342:919-927.
    • (2006) Biochem Biophys Res Commun , vol.342 , pp. 919-927
    • Choung, S.1    Kim, Y.J.2    Kim, S.3    Park, H.4    Choi, Y.5
  • 60
    • 13944261143 scopus 로고    scopus 로고
    • Fully 2'-modified oligonucleotide duplexes with improved in vitro potency and stability compared to unmodified small interfering RNA
    • Allerson C.R., Sioufi N., Jarres R., et al. Fully 2'-modified oligonucleotide duplexes with improved in vitro potency and stability compared to unmodified small interfering RNA. J Med Chem 2005, 48:901-904.
    • (2005) J Med Chem , vol.48 , pp. 901-904
    • Allerson, C.R.1    Sioufi, N.2    Jarres, R.3
  • 62
    • 0034804433 scopus 로고    scopus 로고
    • Escherichia coli ribonuclease III: affinity purification of hexahistidine-tagged enzyme and assays for substrate binding and cleavage
    • Amarasinghe A.K., Calin-Jageman I., Harmouch A., Sun W., Nicholson A.W. Escherichia coli ribonuclease III: affinity purification of hexahistidine-tagged enzyme and assays for substrate binding and cleavage. Methods Enzymol 2001, 342:143-158.
    • (2001) Methods Enzymol , vol.342 , pp. 143-158
    • Amarasinghe, A.K.1    Calin-Jageman, I.2    Harmouch, A.3    Sun, W.4    Nicholson, A.W.5
  • 63
    • 1542306855 scopus 로고    scopus 로고
    • Interferon induction by siRNAs and ssRNAs synthesized by phage polymerase
    • Kim D., Longo M., Han Y., et al. Interferon induction by siRNAs and ssRNAs synthesized by phage polymerase. Nat Biotechnol 2004, 22:321-325.
    • (2004) Nat Biotechnol , vol.22 , pp. 321-325
    • Kim, D.1    Longo, M.2    Han, Y.3
  • 64
    • 0642303887 scopus 로고    scopus 로고
    • Inducible shRNA expression for application in a prostate cancer mouse model
    • Czauderna F., Santel A., Hinz M., et al. Inducible shRNA expression for application in a prostate cancer mouse model. Nucleic Acids Res 2003, 31:e127.
    • (2003) Nucleic Acids Res , vol.31
    • Czauderna, F.1    Santel, A.2    Hinz, M.3
  • 65
    • 42549096043 scopus 로고    scopus 로고
    • Expression strategies for short hairpin RNA interference triggers
    • Rossi J.J. Expression strategies for short hairpin RNA interference triggers. Hum Gene Ther 2008, 19:313-317.
    • (2008) Hum Gene Ther , vol.19 , pp. 313-317
    • Rossi, J.J.1
  • 67
    • 33745299723 scopus 로고    scopus 로고
    • Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways
    • Grimm D., Streetz K.L., Jopling C.L., et al. Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways. Nature 2006, 441:537-541.
    • (2006) Nature , vol.441 , pp. 537-541
    • Grimm, D.1    Streetz, K.L.2    Jopling, C.L.3
  • 68
    • 0042662862 scopus 로고    scopus 로고
    • Establishment of conditional vectors for hairpin siRNA knockdowns
    • Matsukura S., Jones P.A., Takai D. Establishment of conditional vectors for hairpin siRNA knockdowns. Nucleic Acids Res 2003, 31:e77.
    • (2003) Nucleic Acids Res , vol.31
    • Matsukura, S.1    Jones, P.A.2    Takai, D.3
  • 69
    • 0037134020 scopus 로고    scopus 로고
    • A system for stable expression of short interfering RNAs in mammalian cells
    • Brummelkamp T.R., Bernards R., Agami R. A system for stable expression of short interfering RNAs in mammalian cells. Science 2002, 296:550-553.
    • (2002) Science , vol.296 , pp. 550-553
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3
  • 70
    • 10744225153 scopus 로고    scopus 로고
    • Asymmetry in the assembly of the RNAi enzyme complex
    • Schwarz D.S., Hutvágner G., Du T., et al. Asymmetry in the assembly of the RNAi enzyme complex. Cell 2003, 115:199-208.
    • (2003) Cell , vol.115 , pp. 199-208
    • Schwarz, D.S.1    Hutvágner, G.2    Du, T.3
  • 71
    • 0037019339 scopus 로고    scopus 로고
    • RNA interference in adult mice
    • McCaffrey A.P., Meuse L., Pham T.T., et al. RNA interference in adult mice. Nature 2002, 418:38-39.
    • (2002) Nature , vol.418 , pp. 38-39
    • McCaffrey, A.P.1    Meuse, L.2    Pham, T.T.3
  • 72
    • 70349664187 scopus 로고    scopus 로고
    • Novel small interfering RNA-containing solution protecting donor organs in heart transplantation
    • [1 p following 1107]
    • Zheng X., Lian D., Wong A., et al. Novel small interfering RNA-containing solution protecting donor organs in heart transplantation. Circulation 2009, 120:1099-1107. [1 p following 1107].
    • (2009) Circulation , vol.120 , pp. 1099-1107
    • Zheng, X.1    Lian, D.2    Wong, A.3
  • 73
    • 36248946723 scopus 로고    scopus 로고
    • Phospholipase A2 sensitive liposomes for delivery of small interfering RNA (siRNA)
    • Foged C., Nielsen H.M., Frokjaer S. Phospholipase A2 sensitive liposomes for delivery of small interfering RNA (siRNA). J Liposome Res 2007, 17:191-196.
    • (2007) J Liposome Res , vol.17 , pp. 191-196
    • Foged, C.1    Nielsen, H.M.2    Frokjaer, S.3
  • 74
    • 33748126226 scopus 로고    scopus 로고
    • Recent approaches to intracellular delivery of drugs and DNA and organelle targeting
    • Torchilin V.P. Recent approaches to intracellular delivery of drugs and DNA and organelle targeting. Annu Rev Biomed Eng 2006, 8:343-375.
    • (2006) Annu Rev Biomed Eng , vol.8 , pp. 343-375
    • Torchilin, V.P.1
  • 75
    • 9144247189 scopus 로고    scopus 로고
    • Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs
    • Soutschek J., Akinc A., Bramlage B., et al. Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs. Nature 2004, 432:173-178.
    • (2004) Nature , vol.432 , pp. 173-178
    • Soutschek, J.1    Akinc, A.2    Bramlage, B.3
  • 76
    • 67249165389 scopus 로고    scopus 로고
    • VEGF siRNA delivery system using arginine-grafted bioreducible poly(disulfide amine)
    • Kim S.H., Jeong J.H., Kim T., Kim S.W., Bull D.A. VEGF siRNA delivery system using arginine-grafted bioreducible poly(disulfide amine). Mol Pharm 2009, 6:718-726.
    • (2009) Mol Pharm , vol.6 , pp. 718-726
    • Kim, S.H.1    Jeong, J.H.2    Kim, T.3    Kim, S.W.4    Bull, D.A.5
  • 77
    • 33645136607 scopus 로고    scopus 로고
    • Therapeutic short hairpin RNA expression in the liver: viral targets and vectors
    • Grimm D., Kay M.A. Therapeutic short hairpin RNA expression in the liver: viral targets and vectors. Gene Ther 2006, 13:563-575.
    • (2006) Gene Ther , vol.13 , pp. 563-575
    • Grimm, D.1    Kay, M.A.2
  • 78
    • 0036787671 scopus 로고    scopus 로고
    • SiRNA-mediated gene silencing in vitro and in vivo
    • Xia H., Mao Q., Paulson H.L., Davidson B.L. siRNA-mediated gene silencing in vitro and in vivo. Nat Biotechnol 2002, 20:1006-1010.
    • (2002) Nat Biotechnol , vol.20 , pp. 1006-1010
    • Xia, H.1    Mao, Q.2    Paulson, H.L.3    Davidson, B.L.4
  • 79
    • 0037370498 scopus 로고    scopus 로고
    • A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference
    • Rubinson D.A., Dillon C.P., Kwiatkowski A.V., et al. A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference. Nat Genet 2003, 33:401-406.
    • (2003) Nat Genet , vol.33 , pp. 401-406
    • Rubinson, D.A.1    Dillon, C.P.2    Kwiatkowski, A.V.3
  • 80
    • 33645144814 scopus 로고    scopus 로고
    • Lentiviral-mediated delivery of siRNAs for antiviral therapy
    • Morris K.V., Rossi J.J. Lentiviral-mediated delivery of siRNAs for antiviral therapy. Gene Ther 2006, 13:553-558.
    • (2006) Gene Ther , vol.13 , pp. 553-558
    • Morris, K.V.1    Rossi, J.J.2
  • 82
    • 33749537279 scopus 로고    scopus 로고
    • Reinstalling antitumor immunity by inhibiting tumor-derived immunosuppressive molecule IDO through RNA interference
    • Zheng X., Koropatnick J., Li M., et al. Reinstalling antitumor immunity by inhibiting tumor-derived immunosuppressive molecule IDO through RNA interference. J Immunol 2006, 177:5639-5646.
    • (2006) J Immunol , vol.177 , pp. 5639-5646
    • Zheng, X.1    Koropatnick, J.2    Li, M.3
  • 83
    • 33645155231 scopus 로고    scopus 로고
    • Reconstituted influenza virus envelopes as an efficient carrier system for cellular delivery of small-interfering RNAs
    • de Jonge J., Holtrop M., Wilschut J., Huckriede A. Reconstituted influenza virus envelopes as an efficient carrier system for cellular delivery of small-interfering RNAs. Gene Ther 2006, 13:400-411.
    • (2006) Gene Ther , vol.13 , pp. 400-411
    • de Jonge, J.1    Holtrop, M.2    Wilschut, J.3    Huckriede, A.4
  • 84
    • 24944563729 scopus 로고    scopus 로고
    • Efficient delivery of RNA interference effectors via in vitro-packaged SV40 pseudovirions
    • Kimchi-Sarfaty C., Brittain S., Garfield S., et al. Efficient delivery of RNA interference effectors via in vitro-packaged SV40 pseudovirions. Hum Gene Ther 2005, 16:1110-1115.
    • (2005) Hum Gene Ther , vol.16 , pp. 1110-1115
    • Kimchi-Sarfaty, C.1    Brittain, S.2    Garfield, S.3
  • 85
    • 13844254514 scopus 로고    scopus 로고
    • Retroviral gene therapy: safety issues and possible solutions
    • Yi Y., Hahm S.H., Lee K.H. Retroviral gene therapy: safety issues and possible solutions. Curr Gene Ther 2005, 5:25-35.
    • (2005) Curr Gene Ther , vol.5 , pp. 25-35
    • Yi, Y.1    Hahm, S.H.2    Lee, K.H.3
  • 86
    • 13444262170 scopus 로고    scopus 로고
    • Inhibition of respiratory viruses by nasally administered siRNA
    • Bitko V., Musiyenko A., Shulyayeva O., Barik S. Inhibition of respiratory viruses by nasally administered siRNA. Nat Med 2005, 11:50-55.
    • (2005) Nat Med , vol.11 , pp. 50-55
    • Bitko, V.1    Musiyenko, A.2    Shulyayeva, O.3    Barik, S.4
  • 87
    • 1642291631 scopus 로고    scopus 로고
    • Small interfering RNA targeting heme oxygenase-1 enhances ischemia-reperfusion-induced lung apoptosis
    • Zhang X., Shan P., Jiang D., et al. Small interfering RNA targeting heme oxygenase-1 enhances ischemia-reperfusion-induced lung apoptosis. J Biol Chem 2004, 279:10677-10684.
    • (2004) J Biol Chem , vol.279 , pp. 10677-10684
    • Zhang, X.1    Shan, P.2    Jiang, D.3
  • 88
    • 78449309070 scopus 로고    scopus 로고
    • Efficient and targeted delivery of siRNA in vivo
    • Shim M.S., Kwon Y.J. Efficient and targeted delivery of siRNA in vivo. FEBS J 2010, 277:4814-4827.
    • (2010) FEBS J , vol.277 , pp. 4814-4827
    • Shim, M.S.1    Kwon, Y.J.2
  • 89
    • 79952189873 scopus 로고    scopus 로고
    • Naked small interfering RNA of caspase-3 in preservation solution and autologous blood perfusate protects isolated ischemic porcine kidneys
    • Yang B., Hosgood S.A., Nicholson M.L. Naked small interfering RNA of caspase-3 in preservation solution and autologous blood perfusate protects isolated ischemic porcine kidneys. Transplantation 2011, 91:501-507.
    • (2011) Transplantation , vol.91 , pp. 501-507
    • Yang, B.1    Hosgood, S.A.2    Nicholson, M.L.3
  • 90
    • 16244362066 scopus 로고    scopus 로고
    • Cationic lipids enhance siRNA-mediated interferon response in mice
    • Ma Z., Li J., He F., et al. Cationic lipids enhance siRNA-mediated interferon response in mice. Biochem Biophys Res Commun 2005, 330:755-759.
    • (2005) Biochem Biophys Res Commun , vol.330 , pp. 755-759
    • Ma, Z.1    Li, J.2    He, F.3
  • 91
    • 34547134721 scopus 로고    scopus 로고
    • Suppression of immunostimulatory siRNA-driven innate immune activation by 2'-modified RNAs
    • Sioud M., Furset G., Cekaite L. Suppression of immunostimulatory siRNA-driven innate immune activation by 2'-modified RNAs. Biochem Biophys Res Commun 2007, 361:122-126.
    • (2007) Biochem Biophys Res Commun , vol.361 , pp. 122-126
    • Sioud, M.1    Furset, G.2    Cekaite, L.3
  • 92
    • 74049124186 scopus 로고    scopus 로고
    • Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application
    • Jackson A.L., Linsley P.S. Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application. Nat Rev Drug Discov 2010, 9:57-67.
    • (2010) Nat Rev Drug Discov , vol.9 , pp. 57-67
    • Jackson, A.L.1    Linsley, P.S.2
  • 93
    • 10744219688 scopus 로고    scopus 로고
    • Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells
    • Scacheri P.C., Rozenblatt-Rosen O., Caplen N.J., et al. Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells. Proc Natl Acad Sci U S A 2004, 101:1892-1897.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 1892-1897
    • Scacheri, P.C.1    Rozenblatt-Rosen, O.2    Caplen, N.J.3
  • 94
    • 41649115210 scopus 로고    scopus 로고
    • Sequence- and target-independent angiogenesis suppression by siRNA via TLR3
    • Kleinman M.E., Yamada K., Takeda A., et al. Sequence- and target-independent angiogenesis suppression by siRNA via TLR3. Nature 2008, 452:591-597.
    • (2008) Nature , vol.452 , pp. 591-597
    • Kleinman, M.E.1    Yamada, K.2    Takeda, A.3
  • 95
    • 34848926634 scopus 로고    scopus 로고
    • Improved silencing properties using small internally segmented interfering RNAs
    • Bramsen J.B., Laursen M.B., Damgaard C.K., et al. Improved silencing properties using small internally segmented interfering RNAs. Nucleic Acids Res 2007, 35:5886-5897.
    • (2007) Nucleic Acids Res , vol.35 , pp. 5886-5897
    • Bramsen, J.B.1    Laursen, M.B.2    Damgaard, C.K.3
  • 96
    • 38649099969 scopus 로고    scopus 로고
    • Strand-specific 5'-O-methylation of siRNA duplexes controls guide strand selection and targeting specificity
    • Chen P.Y., Weinmann L., Gaidatzis D., et al. Strand-specific 5'-O-methylation of siRNA duplexes controls guide strand selection and targeting specificity. RNA 2008, 14:263-274.
    • (2008) RNA , vol.14 , pp. 263-274
    • Chen, P.Y.1    Weinmann, L.2    Gaidatzis, D.3
  • 97
    • 33745614074 scopus 로고    scopus 로고
    • Position-specific chemical modification of siRNAs reduces "off-target" transcript silencing
    • Jackson A.L., Burchard J., Leake D., et al. Position-specific chemical modification of siRNAs reduces "off-target" transcript silencing. RNA 2006, 12:1197-1205.
    • (2006) RNA , vol.12 , pp. 1197-1205
    • Jackson, A.L.1    Burchard, J.2    Leake, D.3
  • 98
    • 42449091989 scopus 로고    scopus 로고
    • Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect
    • Ui-Tei K., Naito Y., Zenno S., et al. Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect. Nucleic Acids Res 2008, 36:2136-2151.
    • (2008) Nucleic Acids Res , vol.36 , pp. 2136-2151
    • Ui-Tei, K.1    Naito, Y.2    Zenno, S.3
  • 99
    • 67249105434 scopus 로고    scopus 로고
    • A novel mechanism is involved in cationic lipid-mediated functional siRNA delivery
    • Lu J.J., Langer R., Chen J. A novel mechanism is involved in cationic lipid-mediated functional siRNA delivery. Mol Pharm 2009, 6:763-771.
    • (2009) Mol Pharm , vol.6 , pp. 763-771
    • Lu, J.J.1    Langer, R.2    Chen, J.3
  • 100
    • 35148815670 scopus 로고    scopus 로고
    • Mechanisms and optimization of in vivo delivery of lipophilic siRNAs
    • Wolfrum C., Shi S., Jayaprakash K.N., et al. Mechanisms and optimization of in vivo delivery of lipophilic siRNAs. Nat Biotechnol 2007, 25:1149-1157.
    • (2007) Nat Biotechnol , vol.25 , pp. 1149-1157
    • Wolfrum, C.1    Shi, S.2    Jayaprakash, K.N.3
  • 101
    • 41149179660 scopus 로고    scopus 로고
    • Efficient in vivo delivery of siRNA to the liver by conjugation of alpha-tocopherol
    • Nishina K., Unno T., Uno Y., et al. Efficient in vivo delivery of siRNA to the liver by conjugation of alpha-tocopherol. Mol Ther 2008, 16:734-740.
    • (2008) Mol Ther , vol.16 , pp. 734-740
    • Nishina, K.1    Unno, T.2    Uno, Y.3
  • 102
    • 67149093390 scopus 로고    scopus 로고
    • Efficient siRNA delivery into primary cells by a peptide transduction domain-dsRNA binding domain fusion protein
    • Eguchi A., Meade B.R., Chang Y., et al. Efficient siRNA delivery into primary cells by a peptide transduction domain-dsRNA binding domain fusion protein. Nat Biotechnol 2009, 27:567-571.
    • (2009) Nat Biotechnol , vol.27 , pp. 567-571
    • Eguchi, A.1    Meade, B.R.2    Chang, Y.3
  • 103
    • 0842346326 scopus 로고    scopus 로고
    • Conjugate for efficient delivery of short interfering RNA (siRNA) into mammalian cells
    • Muratovska A., Eccles M.R. Conjugate for efficient delivery of short interfering RNA (siRNA) into mammalian cells. FEBS Lett 2004, 558:63-68.
    • (2004) FEBS Lett , vol.558 , pp. 63-68
    • Muratovska, A.1    Eccles, M.R.2
  • 104
    • 70249110439 scopus 로고    scopus 로고
    • Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors
    • Dassie J.P., Liu X., Thomas G.S., et al. Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors. Nat Biotechnol 2009, 27:839-849.
    • (2009) Nat Biotechnol , vol.27 , pp. 839-849
    • Dassie, J.P.1    Liu, X.2    Thomas, G.S.3
  • 105
    • 33747031960 scopus 로고    scopus 로고
    • Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras
    • McNamara J.O., Andrechek E.R., Wang Y., et al. Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras. Nat Biotechnol 2006, 24:1005-1015.
    • (2006) Nat Biotechnol , vol.24 , pp. 1005-1015
    • McNamara, J.O.1    Andrechek, E.R.2    Wang, Y.3
  • 106
    • 66249129385 scopus 로고    scopus 로고
    • Selection, characterization and application of new RNA HIV gp 120 aptamers for facile delivery of Dicer substrate siRNAs into HIV infected cells
    • Zhou J., Swiderski P., Li H., et al. Selection, characterization and application of new RNA HIV gp 120 aptamers for facile delivery of Dicer substrate siRNAs into HIV infected cells. Nucleic Acids Res 2009, 37:3094-3109.
    • (2009) Nucleic Acids Res , vol.37 , pp. 3094-3109
    • Zhou, J.1    Swiderski, P.2    Li, H.3
  • 107
    • 23844474160 scopus 로고    scopus 로고
    • Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors
    • Song E., Zhu P., Lee S., et al. Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors. Nat Biotechnol 2005, 23:709-717.
    • (2005) Nat Biotechnol , vol.23 , pp. 709-717
    • Song, E.1    Zhu, P.2    Lee, S.3
  • 108
    • 49549117077 scopus 로고    scopus 로고
    • T cell-specific siRNA delivery suppresses HIV-1 infection in humanized mice
    • Kumar P., Ban H., Kim S., et al. T cell-specific siRNA delivery suppresses HIV-1 infection in humanized mice. Cell 2008, 134:577-586.
    • (2008) Cell , vol.134 , pp. 577-586
    • Kumar, P.1    Ban, H.2    Kim, S.3
  • 110
    • 0036119051 scopus 로고    scopus 로고
    • Cold ischemia induces isograft arteriopathy, but does not augment allograft arteriopathy in non-immunosuppressed hosts
    • Furukawa Y., Libby P., Stinn J.L., Becker G., Mitchell R.N. Cold ischemia induces isograft arteriopathy, but does not augment allograft arteriopathy in non-immunosuppressed hosts. Am J Pathol 2002, 160:1077-1087.
    • (2002) Am J Pathol , vol.160 , pp. 1077-1087
    • Furukawa, Y.1    Libby, P.2    Stinn, J.L.3    Becker, G.4    Mitchell, R.N.5
  • 111
    • 36849044732 scopus 로고    scopus 로고
    • Nonviral delivery of synthetic siRNAs in vivo
    • Akhtar S., Benter I.F. Nonviral delivery of synthetic siRNAs in vivo. JClin Invest 2007, 117:3623-3632.
    • (2007) JClin Invest , vol.117 , pp. 3623-3632
    • Akhtar, S.1    Benter, I.F.2
  • 112
    • 79951826305 scopus 로고    scopus 로고
    • Intravital 2-photon microscopy assessment of renal protection efficacy of siRNA for p53 in experimental rat kidney transplantation models
    • Imamura R., Isaka Y., Sandoval R.M., et al. Intravital 2-photon microscopy assessment of renal protection efficacy of siRNA for p53 in experimental rat kidney transplantation models. Cell Transplant 2010, 19:1659-1670.
    • (2010) Cell Transplant , vol.19 , pp. 1659-1670
    • Imamura, R.1    Isaka, Y.2    Sandoval, R.M.3
  • 114
    • 0037096712 scopus 로고    scopus 로고
    • Apoptosis and inflammation in renal reperfusion injury
    • Daemen M.A.R.C., de Vries B., Buurman W.A. Apoptosis and inflammation in renal reperfusion injury. Transplantation 2002, 73:1693-1700.
    • (2002) Transplantation , vol.73 , pp. 1693-1700
    • Daemen, M.A.R.C.1    de Vries, B.2    Buurman, W.A.3
  • 115
    • 0037850570 scopus 로고    scopus 로고
    • The immune decision toward allograft tolerance in non-human primates requires early inhibition of innate immunity and induction of immune regulation
    • Hutchings A., Wu J., Asiedu C., et al. The immune decision toward allograft tolerance in non-human primates requires early inhibition of innate immunity and induction of immune regulation. Transpl Immunol 2003, 11:335-344.
    • (2003) Transpl Immunol , vol.11 , pp. 335-344
    • Hutchings, A.1    Wu, J.2    Asiedu, C.3
  • 117
    • 67649610622 scopus 로고    scopus 로고
    • Small interfering RNA targeting RelB protects against renal ischemia-reperfusion injury
    • Feng B., Chen G., Zheng X., et al. Small interfering RNA targeting RelB protects against renal ischemia-reperfusion injury. Transplantation 2009, 87:1283-1289.
    • (2009) Transplantation , vol.87 , pp. 1283-1289
    • Feng, B.1    Chen, G.2    Zheng, X.3
  • 118
    • 77749282951 scopus 로고    scopus 로고
    • TWEAK activates the non-canonical NFkappaB pathway in murine renal tubular cells: modulation of CCL21
    • Sanz A.B., Sanchez-Niño M.D., Izquierdo M.C., et al. TWEAK activates the non-canonical NFkappaB pathway in murine renal tubular cells: modulation of CCL21. PLoS ONE 2010, 5:e8955.
    • (2010) PLoS ONE , vol.5
    • Sanz, A.B.1    Sanchez-Niño, M.D.2    Izquierdo, M.C.3
  • 119
    • 57149105572 scopus 로고    scopus 로고
    • Zag expression during aging suppresses proliferation after kidney injury
    • Schmitt R., Marlier A., Cantley L.G. Zag expression during aging suppresses proliferation after kidney injury. J Am Soc Nephrol 2008, 19:2375-2383.
    • (2008) J Am Soc Nephrol , vol.19 , pp. 2375-2383
    • Schmitt, R.1    Marlier, A.2    Cantley, L.G.3
  • 120
    • 3242776230 scopus 로고    scopus 로고
    • Endothelial injury and dysfunction: role in the extension phase of acute renal failure
    • Molitoris B.A., Sutton T.A. Endothelial injury and dysfunction: role in the extension phase of acute renal failure. Kidney Int 2004, 66:496-499.
    • (2004) Kidney Int , vol.66 , pp. 496-499
    • Molitoris, B.A.1    Sutton, T.A.2
  • 121
    • 6944238701 scopus 로고    scopus 로고
    • Small interfering RNA targeting Fas protects mice against renal ischemia-reperfusion injury
    • Hamar P., Song E., Kökény G., et al. Small interfering RNA targeting Fas protects mice against renal ischemia-reperfusion injury. Proc Natl Acad Sci U S A 2004, 101:14883-14888.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 14883-14888
    • Hamar, P.1    Song, E.2    Kökény, G.3
  • 122
    • 33646556692 scopus 로고    scopus 로고
    • Nitric oxide induces apoptosis in renal tubular epithelial cells through activation of caspase-8
    • Du C., Guan Q., Diao H., Yin Z., Jevnikar A.M. Nitric oxide induces apoptosis in renal tubular epithelial cells through activation of caspase-8. Am J Physiol Renal Physiol 2006, 290:F1044-F1054.
    • (2006) Am J Physiol Renal Physiol , vol.290
    • Du, C.1    Guan, Q.2    Diao, H.3    Yin, Z.4    Jevnikar, A.M.5
  • 123
    • 66449121454 scopus 로고    scopus 로고
    • Regulation of mitochondrial dynamics in acute kidney injury in cell culture and rodent models
    • Brooks C., Wei Q., Cho S., Dong Z. Regulation of mitochondrial dynamics in acute kidney injury in cell culture and rodent models. JClin Invest 2009, 119:1275-1285.
    • (2009) JClin Invest , vol.119 , pp. 1275-1285
    • Brooks, C.1    Wei, Q.2    Cho, S.3    Dong, Z.4
  • 124
    • 33845914939 scopus 로고    scopus 로고
    • Protection of renal ischemia injury using combination gene silencing of complement 3 and caspase 3 genes
    • Zheng X., Zhang X., Sun H., et al. Protection of renal ischemia injury using combination gene silencing of complement 3 and caspase 3 genes. Transplantation 2006, 82:1781-1786.
    • (2006) Transplantation , vol.82 , pp. 1781-1786
    • Zheng, X.1    Zhang, X.2    Sun, H.3
  • 125
    • 33845951057 scopus 로고    scopus 로고
    • Prevention of renal ischemic injury by silencing the expression of renal caspase 3 and caspase 8
    • Zhang X., Zheng X., Sun H., et al. Prevention of renal ischemic injury by silencing the expression of renal caspase 3 and caspase 8. Transplantation 2006, 82:1728-1732.
    • (2006) Transplantation , vol.82 , pp. 1728-1732
    • Zhang, X.1    Zheng, X.2    Sun, H.3
  • 126
    • 77955716367 scopus 로고    scopus 로고
    • Heat shock protein gp96 and NAD(P)H oxidase 4 play key roles in toll-like receptor 4-activated apoptosis during renal ischemia/reperfusion injury
    • Ben Mkaddem S., Pedruzzi E., Werts C., et al. Heat shock protein gp96 and NAD(P)H oxidase 4 play key roles in toll-like receptor 4-activated apoptosis during renal ischemia/reperfusion injury. Cell Death Differ 2010, 17:1474-1485.
    • (2010) Cell Death Differ , vol.17 , pp. 1474-1485
    • Ben Mkaddem, S.1    Pedruzzi, E.2    Werts, C.3
  • 127
    • 44349126743 scopus 로고    scopus 로고
    • TLR4 links podocytes with the innate immune system to mediate glomerular injury
    • Banas M.C., Banas B., Hudkins K.L., et al. TLR4 links podocytes with the innate immune system to mediate glomerular injury. J Am Soc Nephrol 2008, 19:704-713.
    • (2008) J Am Soc Nephrol , vol.19 , pp. 704-713
    • Banas, M.C.1    Banas, B.2    Hudkins, K.L.3
  • 128
    • 33646681900 scopus 로고    scopus 로고
    • Upregulation of chemokine CXCL1/KC by leptospiral membrane lipoprotein preparation in renal tubule epithelial cells
    • Hung C., Chang C., Chen K., et al. Upregulation of chemokine CXCL1/KC by leptospiral membrane lipoprotein preparation in renal tubule epithelial cells. Kidney Int 2006, 69:1814-1822.
    • (2006) Kidney Int , vol.69 , pp. 1814-1822
    • Hung, C.1    Chang, C.2    Chen, K.3
  • 129
    • 66449125984 scopus 로고    scopus 로고
    • Heat shock protein gp96 interactswith protein phosphatase 5 and controls toll-like receptor 2 (TLR2)-mediated activation of extracellular signal-regulated kinase (ERK) 1/2 in post-hypoxic kidney cells
    • Mkaddem S.B., Werts C., Goujon J., et al. Heat shock protein gp96 interactswith protein phosphatase 5 and controls toll-like receptor 2 (TLR2)-mediated activation of extracellular signal-regulated kinase (ERK) 1/2 in post-hypoxic kidney cells. J Biol Chem 2009, 284:12541-12549.
    • (2009) J Biol Chem , vol.284 , pp. 12541-12549
    • Mkaddem, S.B.1    Werts, C.2    Goujon, J.3
  • 130
    • 0037213077 scopus 로고    scopus 로고
    • A small molecule C5a receptor antagonist protects kidneys from ischemia/reperfusion injury in rats
    • Arumugam T.V., Shiels I.A., Strachan A.J., et al. A small molecule C5a receptor antagonist protects kidneys from ischemia/reperfusion injury in rats. Kidney Int 2003, 63:134-142.
    • (2003) Kidney Int , vol.63 , pp. 134-142
    • Arumugam, T.V.1    Shiels, I.A.2    Strachan, A.J.3
  • 131
    • 53149143137 scopus 로고    scopus 로고
    • Gene silencing of complement C5a receptor using siRNA for preventing ischemia/reperfusion injury
    • Zheng X., Zhang X., Feng B., et al. Gene silencing of complement C5a receptor using siRNA for preventing ischemia/reperfusion injury. Am J Pathol 2008, 173:973-980.
    • (2008) Am J Pathol , vol.173 , pp. 973-980
    • Zheng, X.1    Zhang, X.2    Feng, B.3
  • 132
    • 33746897348 scopus 로고    scopus 로고
    • Preventing renal ischemia-reperfusion injury using small interfering RNA by targeting complement 3 gene
    • Zheng X., Feng B., Chen G., et al. Preventing renal ischemia-reperfusion injury using small interfering RNA by targeting complement 3 gene. Am J Transplant 2006, 6:2099-2108.
    • (2006) Am J Transplant , vol.6 , pp. 2099-2108
    • Zheng, X.1    Feng, B.2    Chen, G.3
  • 133
    • 77956123792 scopus 로고    scopus 로고
    • Suppression of Par-4 protects human renal proximal tubule cells from apoptosis induced by oxidative stress
    • Sun B., Lu C., Zhou G., Xing C. Suppression of Par-4 protects human renal proximal tubule cells from apoptosis induced by oxidative stress. Nephron Exp Nephrol 2010, 117:e53-e61.
    • (2010) Nephron Exp Nephrol , vol.117
    • Sun, B.1    Lu, C.2    Zhou, G.3    Xing, C.4
  • 135
    • 0037348329 scopus 로고    scopus 로고
    • RNA interference targeting Fas protects mice from fulminant hepatitis
    • Song E., Lee S., Wang J., et al. RNA interference targeting Fas protects mice from fulminant hepatitis. Nat Med 2003, 9:347-351.
    • (2003) Nat Med , vol.9 , pp. 347-351
    • Song, E.1    Lee, S.2    Wang, J.3
  • 136
    • 34247586108 scopus 로고    scopus 로고
    • Alleviation of ischemia-reperfusion injury in rat liver transplantation by induction of small interference RNA targeting Fas
    • Li X., Zhang J.F., Lu M.Q., et al. Alleviation of ischemia-reperfusion injury in rat liver transplantation by induction of small interference RNA targeting Fas. Langenbecks Arch Surg 2007, 392:345-351.
    • (2007) Langenbecks Arch Surg , vol.392 , pp. 345-351
    • Li, X.1    Zhang, J.F.2    Lu, M.Q.3
  • 137
    • 3843086047 scopus 로고    scopus 로고
    • Caspase-8 and caspase-3 small interfering RNA decreases ischemia/reperfusion injury to the liver in mice
    • Contreras J.L., Vilatoba M., Eckstein C., et al. Caspase-8 and caspase-3 small interfering RNA decreases ischemia/reperfusion injury to the liver in mice. Surgery 2004, 136:390-400.
    • (2004) Surgery , vol.136 , pp. 390-400
    • Contreras, J.L.1    Vilatoba, M.2    Eckstein, C.3
  • 138
    • 33748918887 scopus 로고    scopus 로고
    • Critical role of acidic sphingomyelinase in murine hepatic ischemia-reperfusion injury
    • Llacuna L., Marí M., Garcia-Ruiz C., Fernandez-Checa J.C., Morales A. Critical role of acidic sphingomyelinase in murine hepatic ischemia-reperfusion injury. Hepatology 2006, 44:561-572.
    • (2006) Hepatology , vol.44 , pp. 561-572
    • Llacuna, L.1    Marí, M.2    Garcia-Ruiz, C.3    Fernandez-Checa, J.C.4    Morales, A.5
  • 139
    • 39549111049 scopus 로고    scopus 로고
    • Activation of peroxisome proliferator-activated receptor-alpha inhibits the injurious effects of adiponectin in rat steatotic liver undergoing ischemia-reperfusion
    • Massip-Salcedo M., Zaouali M.A., Padrissa-Altés S., et al. Activation of peroxisome proliferator-activated receptor-alpha inhibits the injurious effects of adiponectin in rat steatotic liver undergoing ischemia-reperfusion. Hepatology 2008, 47:461-472.
    • (2008) Hepatology , vol.47 , pp. 461-472
    • Massip-Salcedo, M.1    Zaouali, M.A.2    Padrissa-Altés, S.3
  • 140
    • 77955149905 scopus 로고    scopus 로고
    • Gadd45beta is a novel mediator of cardiomyocyte apoptosis induced by ischaemia/hypoxia
    • Kim M., Seo E.J., Lee D.H., et al. Gadd45beta is a novel mediator of cardiomyocyte apoptosis induced by ischaemia/hypoxia. Cardiovasc Res 2010, 87:119-126.
    • (2010) Cardiovasc Res , vol.87 , pp. 119-126
    • Kim, M.1    Seo, E.J.2    Lee, D.H.3
  • 141
    • 0034610814 scopus 로고    scopus 로고
    • The language of covalent histone modifications
    • Strahl B.D., Allis C.D. The language of covalent histone modifications. Nature 2000, 403:41-45.
    • (2000) Nature , vol.403 , pp. 41-45
    • Strahl, B.D.1    Allis, C.D.2
  • 142
    • 23044500926 scopus 로고    scopus 로고
    • Linking covalent histone modifications to epigenetics: the rigidity and plasticity of the marks
    • Wang Y., Wysocka J., Perlin J.R., et al. Linking covalent histone modifications to epigenetics: the rigidity and plasticity of the marks. Cold Spring Harb Symp Quant Biol 2004, 69:161-169.
    • (2004) Cold Spring Harb Symp Quant Biol , vol.69 , pp. 161-169
    • Wang, Y.1    Wysocka, J.2    Perlin, J.R.3
  • 143
    • 54049090410 scopus 로고    scopus 로고
    • Histone deacetylase inhibition reduces myocardial ischemia-reperfusion injury in mice
    • Granger A., Abdullah I., Huebner F., et al. Histone deacetylase inhibition reduces myocardial ischemia-reperfusion injury in mice. FASEB J 2008, 22:3549-3560.
    • (2008) FASEB J , vol.22 , pp. 3549-3560
    • Granger, A.1    Abdullah, I.2    Huebner, F.3
  • 144
    • 59149102022 scopus 로고    scopus 로고
    • Secreted frizzled related protein 2 protects cells from apoptosis by blocking the effect of canonical Wnt3a
    • Zhang Z., Deb A., Zhang Z., et al. Secreted frizzled related protein 2 protects cells from apoptosis by blocking the effect of canonical Wnt3a. J Mol Cell Cardiol 2009, 46:370-377.
    • (2009) J Mol Cell Cardiol , vol.46 , pp. 370-377
    • Zhang, Z.1    Deb, A.2    Zhang, Z.3
  • 145
    • 59649107122 scopus 로고    scopus 로고
    • Unique hexosaminidase reduces metabolic survival signal and sensitizes cardiac myocytes to hypoxia/reoxygenation injury
    • Ngoh G.A., Facundo H.T., Hamid T., et al. Unique hexosaminidase reduces metabolic survival signal and sensitizes cardiac myocytes to hypoxia/reoxygenation injury. Circ Res 2009, 104:41-49.
    • (2009) Circ Res , vol.104 , pp. 41-49
    • Ngoh, G.A.1    Facundo, H.T.2    Hamid, T.3
  • 146
    • 33644837102 scopus 로고    scopus 로고
    • Hypoxia inducible factor-1 activation by prolyl 4-hydroxylase-2 gene silencing attenuates myocardial ischemia reperfusion injury
    • Natarajan R., Salloum F.N., Fisher B.J., Kukreja R.C., Fowler A.A. Hypoxia inducible factor-1 activation by prolyl 4-hydroxylase-2 gene silencing attenuates myocardial ischemia reperfusion injury. Circ Res 2006, 98:133-140.
    • (2006) Circ Res , vol.98 , pp. 133-140
    • Natarajan, R.1    Salloum, F.N.2    Fisher, B.J.3    Kukreja, R.C.4    Fowler, A.A.5
  • 147
    • 40049103935 scopus 로고    scopus 로고
    • Small interference RNA against PTP-1B reduces hypoxia/reoxygenation induced apoptosis of rat cardiomyocytes
    • Song H., Zhang Z., Wang L. Small interference RNA against PTP-1B reduces hypoxia/reoxygenation induced apoptosis of rat cardiomyocytes. Apoptosis 2008, 13:383-393.
    • (2008) Apoptosis , vol.13 , pp. 383-393
    • Song, H.1    Zhang, Z.2    Wang, L.3
  • 148
    • 33845577145 scopus 로고    scopus 로고
    • Ischemic acidosis causes apoptosis in coronary endothelial cells through activation of caspase-12
    • Kumar S., Kasseckert S., Kostin S., et al. Ischemic acidosis causes apoptosis in coronary endothelial cells through activation of caspase-12. Cardiovasc Res 2007, 73:172-180.
    • (2007) Cardiovasc Res , vol.73 , pp. 172-180
    • Kumar, S.1    Kasseckert, S.2    Kostin, S.3
  • 149
    • 67650248551 scopus 로고    scopus 로고
    • The targeting of cyclophilin D by RNAi as a novel cardioprotective therapy: evidence from two-photon imaging
    • Kato M., Akao M., Matsumoto-Ida M., et al. The targeting of cyclophilin D by RNAi as a novel cardioprotective therapy: evidence from two-photon imaging. Cardiovasc Res 2009, 83:335-344.
    • (2009) Cardiovasc Res , vol.83 , pp. 335-344
    • Kato, M.1    Akao, M.2    Matsumoto-Ida, M.3
  • 150
    • 58449095140 scopus 로고    scopus 로고
    • Effect of ryanodine receptor 2 gene silencing on ischemia-reperfusion injury of rat myocardial cells
    • Guo Z., Jiao Q., Wang S., Xu M., Gao F. Effect of ryanodine receptor 2 gene silencing on ischemia-reperfusion injury of rat myocardial cells. Zhonghua Bing Li Xue Za Zhi 2008, 37:760-764.
    • (2008) Zhonghua Bing Li Xue Za Zhi , vol.37 , pp. 760-764
    • Guo, Z.1    Jiao, Q.2    Wang, S.3    Xu, M.4    Gao, F.5
  • 151
    • 34548461228 scopus 로고    scopus 로고
    • Activation of hypoxia-inducible factor-1 via prolyl-4 hydoxylase-2 gene silencing attenuates acute inflammatory responses in postischemic myocardium
    • Natarajan R., Salloum F.N., Fisher B.J., et al. Activation of hypoxia-inducible factor-1 via prolyl-4 hydoxylase-2 gene silencing attenuates acute inflammatory responses in postischemic myocardium. Am J Physiol Heart Circ Physiol 2007, 293:H1571-H1580.
    • (2007) Am J Physiol Heart Circ Physiol , vol.293
    • Natarajan, R.1    Salloum, F.N.2    Fisher, B.J.3
  • 152
    • 71749086712 scopus 로고    scopus 로고
    • Dynamin 2 and c-Abl are novel regulators of hyperoxia-mediated NADPH oxidase activation and reactive oxygen species production in caveolin-enriched microdomains of the endothelium
    • Singleton P.A., Pendyala S., Gorshkova I.A., et al. Dynamin 2 and c-Abl are novel regulators of hyperoxia-mediated NADPH oxidase activation and reactive oxygen species production in caveolin-enriched microdomains of the endothelium. J Biol Chem 2009, 284:34964-34975.
    • (2009) J Biol Chem , vol.284 , pp. 34964-34975
    • Singleton, P.A.1    Pendyala, S.2    Gorshkova, I.A.3
  • 153
    • 60849116409 scopus 로고    scopus 로고
    • Early inhibition of HIF-1alpha with small interfering RNA reduces ischemic-reperfused brain injury in rats
    • Chen C., Hu Q., Yan J., et al. Early inhibition of HIF-1alpha with small interfering RNA reduces ischemic-reperfused brain injury in rats. Neurobiol Dis 2009, 33:509-517.
    • (2009) Neurobiol Dis , vol.33 , pp. 509-517
    • Chen, C.1    Hu, Q.2    Yan, J.3
  • 154
    • 78650515010 scopus 로고    scopus 로고
    • Lentivirus-mediated transfer of MMP-9 shRNA provides neuroprotection following focal ischemic brain injury in rats
    • Hu Q., Chen C., Khatibi N.H., et al. Lentivirus-mediated transfer of MMP-9 shRNA provides neuroprotection following focal ischemic brain injury in rats. Brain Res 2011, 1367:347-359.
    • (2011) Brain Res , vol.1367 , pp. 347-359
    • Hu, Q.1    Chen, C.2    Khatibi, N.H.3
  • 155
    • 77953719968 scopus 로고    scopus 로고
    • RNAi targeting micro-calpain increases neuron survival and preserves hippocampal function after global brain ischemia
    • Bevers M.B., Ingleton L.P., Che D., et al. RNAi targeting micro-calpain increases neuron survival and preserves hippocampal function after global brain ischemia. Exp Neurol 2010, 224:170-177.
    • (2010) Exp Neurol , vol.224 , pp. 170-177
    • Bevers, M.B.1    Ingleton, L.P.2    Che, D.3
  • 156
    • 34548431366 scopus 로고    scopus 로고
    • Critical role of calpain I in mitochondrial release of apoptosis-inducing factor in ischemic neuronal injury
    • Cao G., Xing J., Xiao X., et al. Critical role of calpain I in mitochondrial release of apoptosis-inducing factor in ischemic neuronal injury. JNeurosci 2007, 27:9278-9293.
    • (2007) JNeurosci , vol.27 , pp. 9278-9293
    • Cao, G.1    Xing, J.2    Xiao, X.3
  • 157
    • 35848946825 scopus 로고    scopus 로고
    • P38alpha MAP kinase mediates hypoxia-induced motor neuron cell death: a potential target of minocycline's neuroprotective action
    • Guo G., Bhat N.R. p38alpha MAP kinase mediates hypoxia-induced motor neuron cell death: a potential target of minocycline's neuroprotective action. Neurochem Res 2007, 32:2160-2166.
    • (2007) Neurochem Res , vol.32 , pp. 2160-2166
    • Guo, G.1    Bhat, N.R.2
  • 159
    • 3242752773 scopus 로고    scopus 로고
    • Apoptosis in ischemic renal injury: roles of GTP depletion and p53
    • Dagher P.C. Apoptosis in ischemic renal injury: roles of GTP depletion and p53. Kidney Int 2004, 66:506-509.
    • (2004) Kidney Int , vol.66 , pp. 506-509
    • Dagher, P.C.1
  • 160
    • 0029200154 scopus 로고
    • Quantification of apoptotic events in pure and heterogeneous populations of cells using the flow cytometer
    • Fraker P.J., King L.E., Lill-Elghanian D., Telford W.G. Quantification of apoptotic events in pure and heterogeneous populations of cells using the flow cytometer. Methods Cell Biol 1995, 46:57-76.
    • (1995) Methods Cell Biol , vol.46 , pp. 57-76
    • Fraker, P.J.1    King, L.E.2    Lill-Elghanian, D.3    Telford, W.G.4
  • 161
    • 68049136123 scopus 로고    scopus 로고
    • SiRNA targeted to p53 attenuates ischemic and cisplatin-induced acute kidney injury
    • Molitoris B.A., Dagher P.C., Sandoval RM, et al. siRNA targeted to p53 attenuates ischemic and cisplatin-induced acute kidney injury. J Am Soc Nephrol 2009, 20:1754-1764.
    • (2009) J Am Soc Nephrol , vol.20 , pp. 1754-1764
    • Molitoris, B.A.1    Dagher, P.C.2    Sandoval, R.M.3
  • 162
    • 0037836057 scopus 로고    scopus 로고
    • Dedifferentiation and proliferation of surviving epithelial cells in acute renal failure
    • Bonventre J.V. Dedifferentiation and proliferation of surviving epithelial cells in acute renal failure. J Am Soc Nephrol 2003, 14(Suppl 1):S55-S61.
    • (2003) J Am Soc Nephrol , vol.14 , Issue.SUPPL. 1
    • Bonventre, J.V.1
  • 163
    • 0031900627 scopus 로고    scopus 로고
    • Induction of apoptosis in ischemia-reperfusion model of mouse kidney: possible involvement of Fas
    • Nogae S., Miyazaki M., Kobayashi N., et al. Induction of apoptosis in ischemia-reperfusion model of mouse kidney: possible involvement of Fas. J Am Soc Nephrol 1998, 9:620-631.
    • (1998) J Am Soc Nephrol , vol.9 , pp. 620-631
    • Nogae, S.1    Miyazaki, M.2    Kobayashi, N.3
  • 164
    • 0242721628 scopus 로고    scopus 로고
    • Renal tubular epithelial cell apoptosis by Fas-FasL-dependent self-injury can augment renal allograft injury
    • Du C., Guan Q., Yin Z., et al. Renal tubular epithelial cell apoptosis by Fas-FasL-dependent self-injury can augment renal allograft injury. Transplant Proc 2003, 35:2481-2482.
    • (2003) Transplant Proc , vol.35 , pp. 2481-2482
    • Du, C.1    Guan, Q.2    Yin, Z.3
  • 165
    • 0033608816 scopus 로고    scopus 로고
    • Involvement of endogenous interleukin-10 and tumor necrosis factor-alpha in renal ischemia-reperfusion injury
    • Daemen M.A., van de Ven M.W., Heineman E., Buurman W.A. Involvement of endogenous interleukin-10 and tumor necrosis factor-alpha in renal ischemia-reperfusion injury. Transplantation 1999, 67:792-800.
    • (1999) Transplantation , vol.67 , pp. 792-800
    • Daemen, M.A.1    van de Ven, M.W.2    Heineman, E.3    Buurman, W.A.4
  • 166
    • 0033162780 scopus 로고    scopus 로고
    • Review article: the role of tumor necrosis factor in renal ischemia-reperfusion injury
    • Donnahoo K.K., Shames B.D., Harken A.H., Meldrum D.R. Review article: the role of tumor necrosis factor in renal ischemia-reperfusion injury. J Urol 1999, 162:196-203.
    • (1999) J Urol , vol.162 , pp. 196-203
    • Donnahoo, K.K.1    Shames, B.D.2    Harken, A.H.3    Meldrum, D.R.4
  • 167
    • 33947651719 scopus 로고    scopus 로고
    • Resident dendritic cells are the predominant TNF-secreting cell in early renal ischemia-reperfusion injury
    • Dong X., Swaminathan S., Bachman L.A., et al. Resident dendritic cells are the predominant TNF-secreting cell in early renal ischemia-reperfusion injury. Kidney Int 2007, 71:619-628.
    • (2007) Kidney Int , vol.71 , pp. 619-628
    • Dong, X.1    Swaminathan, S.2    Bachman, L.A.3
  • 168
    • 33748510411 scopus 로고    scopus 로고
    • Increasing resistance of tubular epithelial cells to apoptosis by shRNA therapy ameliorates renal ischemia-reperfusion injury
    • Du C., Wang S., Diao H., et al. Increasing resistance of tubular epithelial cells to apoptosis by shRNA therapy ameliorates renal ischemia-reperfusion injury. Am J Transplant 2006, 6:2256-2267.
    • (2006) Am J Transplant , vol.6 , pp. 2256-2267
    • Du, C.1    Wang, S.2    Diao, H.3
  • 169
    • 0034082750 scopus 로고    scopus 로고
    • Predominant role for C5b-9 in renal ischemia/reperfusion injury
    • Zhou W., Farrar C.A., Abe K., et al. Predominant role for C5b-9 in renal ischemia/reperfusion injury. J Clin Invest 2000, 105:1363-1371.
    • (2000) J Clin Invest , vol.105 , pp. 1363-1371
    • Zhou, W.1    Farrar, C.A.2    Abe, K.3
  • 170
    • 0347997275 scopus 로고    scopus 로고
    • Complement factor C5a mediates renal ischemia-reperfusion injury independent from neutrophils
    • de Vries B., Köhl J., Leclercq W.K.G., et al. Complement factor C5a mediates renal ischemia-reperfusion injury independent from neutrophils. J Immunol 2003, 170:3883-3889.
    • (2003) J Immunol , vol.170 , pp. 3883-3889
    • de Vries, B.1    Köhl, J.2    Leclercq, W.K.G.3
  • 171
    • 34249104864 scopus 로고    scopus 로고
    • The many effects of complement C3- and C5-binding proteins in renal injury
    • Puri T.S., Quigg R.J. The many effects of complement C3- and C5-binding proteins in renal injury. Semin Nephrol 2007, 27:321-337.
    • (2007) Semin Nephrol , vol.27 , pp. 321-337
    • Puri, T.S.1    Quigg, R.J.2
  • 172
    • 1542619241 scopus 로고    scopus 로고
    • Critical protection from renal ischemia reperfusion injury by CD55 and CD59
    • Yamada K., Miwa T., Liu J., Nangaku M., Song W. Critical protection from renal ischemia reperfusion injury by CD55 and CD59. JImmunol 2004, 172:3869-3875.
    • (2004) JImmunol , vol.172 , pp. 3869-3875
    • Yamada, K.1    Miwa, T.2    Liu, J.3    Nangaku, M.4    Song, W.5
  • 173
    • 7444252664 scopus 로고    scopus 로고
    • Reactive oxygen species and molecular biology of ischemia/reperfusion
    • Toledo-Pereyra L.H., Lopez-Neblina F., Toledo A.H. Reactive oxygen species and molecular biology of ischemia/reperfusion. Ann Transplant 2004, 9:81-83.
    • (2004) Ann Transplant , vol.9 , pp. 81-83
    • Toledo-Pereyra, L.H.1    Lopez-Neblina, F.2    Toledo, A.H.3
  • 174
    • 33947227308 scopus 로고    scopus 로고
    • ROS generation in endothelial hypoxia and reoxygenation stimulates MAP kinase signaling and kinase-dependent neutrophil recruitment
    • Millar T.M., Phan V., Tibbles L.A. ROS generation in endothelial hypoxia and reoxygenation stimulates MAP kinase signaling and kinase-dependent neutrophil recruitment. Free Radic Biol Med 2007, 42:1165-1177.
    • (2007) Free Radic Biol Med , vol.42 , pp. 1165-1177
    • Millar, T.M.1    Phan, V.2    Tibbles, L.A.3
  • 175
    • 1842685135 scopus 로고    scopus 로고
    • Ischemia/reperfusion induces the recruitment of leukocytes from whole blood under flow conditions
    • Cassie S., Masterson M.F., Polukoshko A., Viskovic M.M., Tibbles L.A. Ischemia/reperfusion induces the recruitment of leukocytes from whole blood under flow conditions. Free Radic Biol Med 2004, 36:1102-1111.
    • (2004) Free Radic Biol Med , vol.36 , pp. 1102-1111
    • Cassie, S.1    Masterson, M.F.2    Polukoshko, A.3    Viskovic, M.M.4    Tibbles, L.A.5
  • 176
    • 33750473414 scopus 로고    scopus 로고
    • Interleukin-6 and STAT3 protect the liver from hepatic ischemia and reperfusion injury during ischemic preconditioning
    • Matsumoto T., O'Malley K., Efron P.A., et al. Interleukin-6 and STAT3 protect the liver from hepatic ischemia and reperfusion injury during ischemic preconditioning. Surgery 2006, 140:793-802.
    • (2006) Surgery , vol.140 , pp. 793-802
    • Matsumoto, T.1    O'Malley, K.2    Efron, P.A.3
  • 177
    • 77956174743 scopus 로고    scopus 로고
    • Transient upregulation of PGC-1alpha diminishes cardiac ischemia tolerance via upregulation of ANT1
    • Lynn E.G., Stevens M.V., Wong R.P., et al. Transient upregulation of PGC-1alpha diminishes cardiac ischemia tolerance via upregulation of ANT1. J Mol Cell Cardiol 2010, 49:693-698.
    • (2010) J Mol Cell Cardiol , vol.49 , pp. 693-698
    • Lynn, E.G.1    Stevens, M.V.2    Wong, R.P.3
  • 179
    • 33846845067 scopus 로고    scopus 로고
    • Secreted frizzled related protein 2 (Sfrp2) is the key Akt-mesenchymal stem cell-released paracrine factor mediating myocardial survival and repair
    • Mirotsou M., Zhang Z., Deb A., et al. Secreted frizzled related protein 2 (Sfrp2) is the key Akt-mesenchymal stem cell-released paracrine factor mediating myocardial survival and repair. Proc Natl Acad Sci U S A 2007, 104:1643-1648.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 1643-1648
    • Mirotsou, M.1    Zhang, Z.2    Deb, A.3
  • 180
    • 0021280147 scopus 로고
    • Topography and polypeptide distribution of terminal N-acetylglucosamine residues on the surfaces of intact lymphocytes. Evidence for O-linked GlcNAc
    • Torres C.R., Hart G.W. Topography and polypeptide distribution of terminal N-acetylglucosamine residues on the surfaces of intact lymphocytes. Evidence for O-linked GlcNAc. J Biol Chem 1984, 259:3308-3317.
    • (1984) J Biol Chem , vol.259 , pp. 3308-3317
    • Torres, C.R.1    Hart, G.W.2
  • 181
    • 3042534011 scopus 로고    scopus 로고
    • Dynamic O-GlcNAc modification of nucleocytoplasmic proteins in response to stress. A survival response of mammalian cells
    • Zachara N.E., O'Donnell N., Cheung W.D., et al. Dynamic O-GlcNAc modification of nucleocytoplasmic proteins in response to stress. A survival response of mammalian cells. J Biol Chem 2004, 279:30133-30142.
    • (2004) J Biol Chem , vol.279 , pp. 30133-30142
    • Zachara, N.E.1    O'Donnell, N.2    Cheung, W.D.3
  • 182
    • 78649817029 scopus 로고    scopus 로고
    • Is ryanodine receptor phosphorylation key to the fight or flight response and heart failure
    • Eschenhagen T. Is ryanodine receptor phosphorylation key to the fight or flight response and heart failure. J Clin Invest 2010, 120:4197-4203.
    • (2010) J Clin Invest , vol.120 , pp. 4197-4203
    • Eschenhagen, T.1
  • 183
    • 77649238072 scopus 로고    scopus 로고
    • RNAi targeting ryanodine receptor 2 protects rat cardiomyocytes from injury caused by simulated ischemia-reperfusion
    • Guo Z., Wang S., Jiao Q., Xu M., Gao F. RNAi targeting ryanodine receptor 2 protects rat cardiomyocytes from injury caused by simulated ischemia-reperfusion. Biomed Pharmacother 2010, 64:184-190.
    • (2010) Biomed Pharmacother , vol.64 , pp. 184-190
    • Guo, Z.1    Wang, S.2    Jiao, Q.3    Xu, M.4    Gao, F.5
  • 184
    • 52449133753 scopus 로고    scopus 로고
    • Tamm-Horsfall protein protects the kidney from ischemic injury by decreasing inflammation and altering TLR4 expression
    • El-Achkar T.M., Wu X., Rauchman M., et al. Tamm-Horsfall protein protects the kidney from ischemic injury by decreasing inflammation and altering TLR4 expression. Am J Physiol Renal Physiol 2008, 295:F534-F544.
    • (2008) Am J Physiol Renal Physiol , vol.295
    • El-Achkar, T.M.1    Wu, X.2    Rauchman, M.3
  • 185
    • 30744462300 scopus 로고    scopus 로고
    • Regulation of lung injury and repair by toll-like receptors and hyaluronan
    • Jiang D., Liang J., Fan J., et al. Regulation of lung injury and repair by toll-like receptors and hyaluronan. Nat Med 2005, 11:1173-1179.
    • (2005) Nat Med , vol.11 , pp. 1173-1179
    • Jiang, D.1    Liang, J.2    Fan, J.3
  • 186
    • 0029843370 scopus 로고    scopus 로고
    • Experimentally-induced warm renal ischemia induces cortical accumulation of hyaluronan in the kidney
    • Johnsson C., Tufveson G., Wahlberg J., Hällgren R. Experimentally-induced warm renal ischemia induces cortical accumulation of hyaluronan in the kidney. Kidney Int 1996, 50:1224-1229.
    • (1996) Kidney Int , vol.50 , pp. 1224-1229
    • Johnsson, C.1    Tufveson, G.2    Wahlberg, J.3    Hällgren, R.4
  • 187
    • 2342428467 scopus 로고    scopus 로고
    • Hyaluronan fragments stimulate endothelial recognition of injury through TLR4
    • Taylor K.R., Trowbridge J.M., Rudisill J.A., et al. Hyaluronan fragments stimulate endothelial recognition of injury through TLR4. J Biol Chem 2004, 279:17079-17084.
    • (2004) J Biol Chem , vol.279 , pp. 17079-17084
    • Taylor, K.R.1    Trowbridge, J.M.2    Rudisill, J.A.3
  • 188
    • 49649085838 scopus 로고    scopus 로고
    • Mechanisms underlying blockade of allograft acceptance by TLR ligands
    • Porrett P.M., Yuan X., LaRosa D.F., et al. Mechanisms underlying blockade of allograft acceptance by TLR ligands. J Immunol 2008, 181:1692-1699.
    • (2008) J Immunol , vol.181 , pp. 1692-1699
    • Porrett, P.M.1    Yuan, X.2    LaRosa, D.F.3
  • 189
    • 31144479123 scopus 로고    scopus 로고
    • TLR agonists abrogate costimulation blockade-induced prolongation of skin allografts
    • Thornley T.B., Brehm M.A., Markees T.G., et al. TLR agonists abrogate costimulation blockade-induced prolongation of skin allografts. JImmunol 2006, 176:1561-1570.
    • (2006) JImmunol , vol.176 , pp. 1561-1570
    • Thornley, T.B.1    Brehm, M.A.2    Markees, T.G.3
  • 190
    • 4444293184 scopus 로고    scopus 로고
    • Toll-like receptors and other links between innate and acquired alloimmunity
    • Goldstein D.R. Toll-like receptors and other links between innate and acquired alloimmunity. Curr Opin Immunol 2004, 16:538-544.
    • (2004) Curr Opin Immunol , vol.16 , pp. 538-544
    • Goldstein, D.R.1
  • 191
    • 17644399470 scopus 로고    scopus 로고
    • Innate immunity and organ transplantation: the potential role of toll-like receptors
    • Andrade C.F., Waddell T.K., Keshavjee S., Liu M. Innate immunity and organ transplantation: the potential role of toll-like receptors. Am J Transplant 2005, 5:969-975.
    • (2005) Am J Transplant , vol.5 , pp. 969-975
    • Andrade, C.F.1    Waddell, T.K.2    Keshavjee, S.3    Liu, M.4
  • 192
    • 0037974914 scopus 로고    scopus 로고
    • Critical role of the toll-like receptor signal adaptor protein MyD88 in acute allograft rejection
    • Goldstein D.R., Tesar B.M., Akira S., Lakkis F.G. Critical role of the toll-like receptor signal adaptor protein MyD88 in acute allograft rejection. J Clin Invest 2003, 111:1571-1578.
    • (2003) J Clin Invest , vol.111 , pp. 1571-1578
    • Goldstein, D.R.1    Tesar, B.M.2    Akira, S.3    Lakkis, F.G.4
  • 194
    • 77957887259 scopus 로고    scopus 로고
    • The NLRP3 inflammasome promotes renal inflammation and contributes to CKD
    • Vilaysane A., Chun J., Seamone M.E., et al. The NLRP3 inflammasome promotes renal inflammation and contributes to CKD. J Am Soc Nephrol 2010, 21:1732-1744.
    • (2010) J Am Soc Nephrol , vol.21 , pp. 1732-1744
    • Vilaysane, A.1    Chun, J.2    Seamone, M.E.3
  • 195
    • 10344233176 scopus 로고    scopus 로고
    • Regulatory T cell suppression and anergy are differentially regulated by proinflammatory cytokines produced by TLR-activated dendritic cells
    • Kubo T., Hatton R.D., Oliver J., et al. Regulatory T cell suppression and anergy are differentially regulated by proinflammatory cytokines produced by TLR-activated dendritic cells. J Immunol 2004, 173:7249-7258.
    • (2004) J Immunol , vol.173 , pp. 7249-7258
    • Kubo, T.1    Hatton, R.D.2    Oliver, J.3
  • 196
    • 67649871044 scopus 로고    scopus 로고
    • Antagonistic effect of toll-like receptor signaling and bacterial infections on transplantation tolerance
    • Alegre M., Chen L., Wang T., et al. Antagonistic effect of toll-like receptor signaling and bacterial infections on transplantation tolerance. Transplantation 2009, 87(9 Suppl):S77-S79.
    • (2009) Transplantation , vol.87 , Issue.9 SUPPL.
    • Alegre, M.1    Chen, L.2    Wang, T.3
  • 197
    • 33748490733 scopus 로고    scopus 로고
    • TLR engagement prevents transplantation tolerance
    • Chen L., Wang T., Zhou P., et al. TLR engagement prevents transplantation tolerance. Am J Transplant 2006, 6:2282-2291.
    • (2006) Am J Transplant , vol.6 , pp. 2282-2291
    • Chen, L.1    Wang, T.2    Zhou, P.3
  • 198
    • 33749515463 scopus 로고    scopus 로고
    • Absence of innate MyD88 signaling promotes inducible allograft acceptance
    • Walker W.E., Nasr I.W., Camirand G., et al. Absence of innate MyD88 signaling promotes inducible allograft acceptance. J Immunol 2006, 177:5307-5316.
    • (2006) J Immunol , vol.177 , pp. 5307-5316
    • Walker, W.E.1    Nasr, I.W.2    Camirand, G.3
  • 199
    • 34347222876 scopus 로고    scopus 로고
    • Toll-like receptors and their role in transplantation
    • Tesar B.M., Goldstein D.R. Toll-like receptors and their role in transplantation. Front Biosci 2007, 12:4221-4238.
    • (2007) Front Biosci , vol.12 , pp. 4221-4238
    • Tesar, B.M.1    Goldstein, D.R.2
  • 200
    • 77950299026 scopus 로고    scopus 로고
    • TLR signals promote IL-6/IL-17-dependent transplant rejection
    • Chen L., Ahmed E., Wang T., et al. TLR signals promote IL-6/IL-17-dependent transplant rejection. J Immunol 2009, 182:6217-6225.
    • (2009) J Immunol , vol.182 , pp. 6217-6225
    • Chen, L.1    Ahmed, E.2    Wang, T.3
  • 201
    • 34948835806 scopus 로고    scopus 로고
    • TLR4 activation mediates kidney ischemia/reperfusion injury
    • Wu H., Chen G., Wyburn K.R., et al. TLR4 activation mediates kidney ischemia/reperfusion injury. J Clin Invest 2007, 117:2847-2859.
    • (2007) J Clin Invest , vol.117 , pp. 2847-2859
    • Wu, H.1    Chen, G.2    Wyburn, K.R.3
  • 202
    • 34248140689 scopus 로고    scopus 로고
    • TLR2 is constitutively expressed within the kidney and participates in ischemic renal injury through both MyD88-dependent and -independent pathways
    • Shigeoka A.A., Holscher T.D., King A.J., et al. TLR2 is constitutively expressed within the kidney and participates in ischemic renal injury through both MyD88-dependent and -independent pathways. JImmunol 2007, 178:6252-6258.
    • (2007) JImmunol , vol.178 , pp. 6252-6258
    • Shigeoka, A.A.1    Holscher, T.D.2    King, A.J.3
  • 203
    • 34250164226 scopus 로고    scopus 로고
    • The identity of innate immune activators in organ transplantation: origins from within or exterior to the host
    • Goldstein D.R. The identity of innate immune activators in organ transplantation: origins from within or exterior to the host. Am J Transplant 2007, 7:1692-1694.
    • (2007) Am J Transplant , vol.7 , pp. 1692-1694
    • Goldstein, D.R.1
  • 204
    • 0027319826 scopus 로고
    • Increased hyaluronan in acutely rejecting human kidney grafts
    • Wells A., Larsson E., Hanás E., et al. Increased hyaluronan in acutely rejecting human kidney grafts. Transplantation 1993, 55:1346-1349.
    • (1993) Transplantation , vol.55 , pp. 1346-1349
    • Wells, A.1    Larsson, E.2    Hanás, E.3
  • 205
    • 62549100072 scopus 로고    scopus 로고
    • Donor Toll-like receptor 4 contributes to ischemia and reperfusion injury following human kidney transplantation
    • Krüger B., Krick S., Dhillon N., et al. Donor Toll-like receptor 4 contributes to ischemia and reperfusion injury following human kidney transplantation. Proc Natl Acad Sci U S A 2009, 106:3390-3395.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 3390-3395
    • Krüger, B.1    Krick, S.2    Dhillon, N.3
  • 206
    • 56349089258 scopus 로고    scopus 로고
    • Toll-like receptor-4 coordinates the innate immune response of the kidney to renal ischemia/reperfusion injury
    • Pulskens W.P., Teske G.J., Butter L.M., et al. Toll-like receptor-4 coordinates the innate immune response of the kidney to renal ischemia/reperfusion injury. PLoS ONE 2008, 3:e3596.
    • (2008) PLoS ONE , vol.3
    • Pulskens, W.P.1    Teske, G.J.2    Butter, L.M.3
  • 208
    • 34247097120 scopus 로고    scopus 로고
    • C5aR-mediated myocardial ischemia/reperfusion injury
    • Zhang H., Qin G., Liang G., et al. C5aR-mediated myocardial ischemia/reperfusion injury. Biochem Biophys Res Commun 2007, 357:446-452.
    • (2007) Biochem Biophys Res Commun , vol.357 , pp. 446-452
    • Zhang, H.1    Qin, G.2    Liang, G.3
  • 209
    • 0028901180 scopus 로고
    • Regulation of the complement cascade by soluble complement receptor type 1. Protective effect in experimental liver ischemia and reperfusion
    • Chávez-Cartaya R.E., DeSola G.P., Wright L., Jamieson N.V., White D.J. Regulation of the complement cascade by soluble complement receptor type 1. Protective effect in experimental liver ischemia and reperfusion. Transplantation 1995, 59:1047-1052.
    • (1995) Transplantation , vol.59 , pp. 1047-1052
    • Chávez-Cartaya, R.E.1    DeSola, G.P.2    Wright, L.3    Jamieson, N.V.4    White, D.J.5
  • 210
    • 0028966351 scopus 로고
    • Complement in organ transplantation. Contributions to inflammation, injury, and rejection
    • Baldwin W.M., Pruitt S.K., Brauer R.B., Daha M.R., Sanfilippo F. Complement in organ transplantation. Contributions to inflammation, injury, and rejection. Transplantation 1995, 59:797-808.
    • (1995) Transplantation , vol.59 , pp. 797-808
    • Baldwin, W.M.1    Pruitt, S.K.2    Brauer, R.B.3    Daha, M.R.4    Sanfilippo, F.5
  • 211
    • 0037442163 scopus 로고    scopus 로고
    • Inhibition of complement factor C5 protects against renal ischemia-reperfusion injury: inhibition of late apoptosis and inflammation
    • De Vries B., Matthijsen R.A., Wolfs T.G., Van Bijnen A.A., Heeringa P., Buurman W.A. Inhibition of complement factor C5 protects against renal ischemia-reperfusion injury: inhibition of late apoptosis and inflammation. Transplantation 2003, 75:375-382.
    • (2003) Transplantation , vol.75 , pp. 375-382
    • De Vries, B.1    Matthijsen, R.A.2    Wolfs, T.G.3    Van Bijnen, A.A.4    Heeringa, P.5    Buurman, W.A.6
  • 212
    • 0032499629 scopus 로고    scopus 로고
    • Myocardial infarction and apoptosis after myocardial ischemia and reperfusion: role of the terminal complement components and inhibition by anti-C5 therapy
    • Vakeva A.P., Agah A., Rollins S.A., et al. Myocardial infarction and apoptosis after myocardial ischemia and reperfusion: role of the terminal complement components and inhibition by anti-C5 therapy. Circulation 1998, 97:2259-2267.
    • (1998) Circulation , vol.97 , pp. 2259-2267
    • Vakeva, A.P.1    Agah, A.2    Rollins, S.A.3
  • 213
    • 58149345075 scopus 로고    scopus 로고
    • Posttransplant ischemia-reperfusion injury in transplanted heart is prevented by a minibody to the fifth component of complement
    • Ferraresso M., Macor P., Valente M., et al. Posttransplant ischemia-reperfusion injury in transplanted heart is prevented by a minibody to the fifth component of complement. Transplantation 2008, 86:1445-1451.
    • (2008) Transplantation , vol.86 , pp. 1445-1451
    • Ferraresso, M.1    Macor, P.2    Valente, M.3
  • 214
    • 0001974662 scopus 로고    scopus 로고
    • Inflammatory cytokines induce apoptotic and necrotic cell shedding from human proximal tubular epithelial cell monolayers
    • Glynne P.A., Evans T.J. Inflammatory cytokines induce apoptotic and necrotic cell shedding from human proximal tubular epithelial cell monolayers. Kidney Int 1999, 55:2573-2597.
    • (1999) Kidney Int , vol.55 , pp. 2573-2597
    • Glynne, P.A.1    Evans, T.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.