Suppression of immunostimulatory siRNA-driven innate immune activation by 2′-modified RNAs

Biochemical and Biophysical Research Communications

Volumn 361, Issue 1, 2007, Pages 122-126

  Sioud, Mouldy ^a   Furset, Gro ^a   Cekaite, Lina ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

2 Modified RNAs; Innate immunity; RNA interference; siRNA; Suppressive oligonucleotides; Toll like receptors

Indexed keywords

2' O METHYLURIDINE; DEOXYURIDINE; DOUBLE STRANDED RNA; OLIGONUCLEOTIDE; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; URIDINE DERIVATIVE;

ARTICLE; CONTROLLED STUDY; DNA MICROARRAY; DOWN REGULATION; DRUG INHIBITION; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNIZATION; IMMUNOSTIMULATION; IMMUNOSUPPRESSIVE TREATMENT; MONOCYTE; PRIORITY JOURNAL; PROTEIN MODIFICATION; RNA SEQUENCE;

ADJUVANTS, IMMUNOLOGIC; ADULT; GENE EXPRESSION; HUMANS; IMMUNITY, NATURAL; IMMUNOSUPPRESSIVE AGENTS; MONOCYTES; OLIGORIBONUCLEOTIDES; RNA INTERFERENCE; RNA, SMALL INTERFERING; TOLL-LIKE RECEPTORS;

EID: 34547134721     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.06.177     Document Type: Article

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