메뉴 건너뛰기




Volumn 1002, Issue , 2003, Pages 56-62

Short Interfering RNA (siRNA) - Mediated RNA Interference (RNAi) in Human Cells

Author keywords

RNA interference; RNAi gene silencing; Short interfering RNAs; siRNAs

Indexed keywords

ANTHRACYCLINE; DOUBLE STRANDED RNA; NUCLEOTIDE; SMALL INTERFERING RNA; TAXANE DERIVATIVE; TRASTUZUMAB;

EID: 1342268939     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1196/annals.1281.007     Document Type: Conference Paper
Times cited : (74)

References (63)
  • 1
    • 0035863097 scopus 로고    scopus 로고
    • RNA interference is mediated by 21- and 22-nucleotide RNAs
    • ELBASHIR, S.M., W. LENDECKEL & T. TUSCHL. 2001. RNA interference is mediated by 21-and 22-nucleotide RNAs. Genes Dev. 15: 188-200.
    • (2001) Genes Dev. , vol.15 , pp. 188-200
    • Elbashir, S.M.1    Lendeckel, W.2    Tuschl, T.3
  • 2
    • 0035803583 scopus 로고    scopus 로고
    • Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate
    • ELBASHIR, S.M. et al. 2001. Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate. EMBO J. 20: 6877-6888.
    • (2001) EMBO J. , vol.20 , pp. 6877-6888
    • Elbashir, S.M.1
  • 3
    • 0033615491 scopus 로고    scopus 로고
    • A species of small antisense RNA in post-transcriptional gene silencing in plants
    • HAMILTON, A.J. & D.C. BAULCOMBE. 1999. A species of small antisense RNA in post-transcriptional gene silencing in plants. Science 286: 950-952.
    • (1999) Science , vol.286 , pp. 950-952
    • Hamilton, A.J.1    Baulcombe, D.C.2
  • 4
    • 0001359591 scopus 로고
    • Introduction of a chimeric chalcone synthase gene into petunia results in reversible co-suppression of homologous genes in trans
    • NAPOLI, C., C. LEMIEUX & R. JORGENSEN. 1990. Introduction of a chimeric chalcone synthase gene into petunia results in reversible co-suppression of homologous genes in trans. Plant Cell 2: 279-289.
    • (1990) Plant Cell , vol.2 , pp. 279-289
    • Napoli, C.1    Lemieux, C.2    Jorgensen, R.3
  • 5
    • 0026441194 scopus 로고
    • Quelling: Transient inactivation of gene expression in Neurospora crassa by transformation with homologous sequences
    • ROMANO, N. & G. MACINO. 1992. Quelling: transient inactivation of gene expression in Neurospora crassa by transformation with homologous sequences. Mol. Microbiol. 6: 3343-3353.
    • (1992) Mol. Microbiol. , vol.6 , pp. 3343-3353
    • Romano, N.1    Macino, G.2
  • 6
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • FIRE, A. et al. 1998. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391: 806-811.
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1
  • 7
    • 0032443021 scopus 로고    scopus 로고
    • Use of dsRNA-mediated genetic interference to demonstrate that frizzled and frizzled 2 act in the wingless pathway
    • KENNERDELL, J.R. & R.W. CARTHEW. 1998. Use of dsRNA-mediated genetic interference to demonstrate that frizzled and frizzled 2 act in the wingless pathway. Cell 95: 1017-1026.
    • (1998) Cell , vol.95 , pp. 1017-1026
    • Kennerdell, J.R.1    Carthew, R.W.2
  • 8
    • 0033573924 scopus 로고    scopus 로고
    • Targeted disruption of gene function in Drosophila by RNA interference (RNA-i): A role for nautilus in embryonic somatic muscle formation
    • MISQUITTA, L. & B.M. PATERSON. 1999. Targeted disruption of gene function in Drosophila by RNA interference (RNA-i): a role for nautilus in embryonic somatic muscle formation. Proc. Natl. Acad. Sci. USA 96: 1451-1456.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 1451-1456
    • Misquitta, L.1    Paterson, B.M.2
  • 9
    • 0035905766 scopus 로고    scopus 로고
    • Role for a bidentate ribonuclease in the initiation step of RNA interference
    • BERNSTEIN, E. et al. 2001. Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 409: 363-366.
    • (2001) Nature , vol.409 , pp. 363-366
    • Bernstein, E.1
  • 10
    • 0034673638 scopus 로고    scopus 로고
    • An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
    • HAMMOND, S.M. et al. 2000. An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells. Nature 404: 293-296.
    • (2000) Nature , vol.404 , pp. 293-296
    • Hammond, S.M.1
  • 11
    • 0035839109 scopus 로고    scopus 로고
    • Argonaute2, a link between genetic and biochemical analyses of RNAi
    • HAMMOND, S.M. et al. 2001. Argonaute2, a link between genetic and biochemical analyses of RNAi. Science 293: 1146-1150.
    • (2001) Science , vol.293 , pp. 1146-1150
    • Hammond, S.M.1
  • 12
    • 0034737298 scopus 로고    scopus 로고
    • RNAi: Double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals
    • ZAMORE, P.D. et al. 2000. RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell 101: 25-33.
    • (2000) Cell , vol.101 , pp. 25-33
    • Zamore, P.D.1
  • 13
    • 0030725442 scopus 로고    scopus 로고
    • The double-stranded RNA-dependent protein kinase PKR: Structure and function
    • CLEMENS, M.J. & A. ELIA. 1997. The double-stranded RNA-dependent protein kinase PKR: structure and function. J. Interferon Cytokine Res. 17: 503-524.
    • (1997) J. Interferon Cytokine Res. , vol.17 , pp. 503-524
    • Clemens, M.J.1    Elia, A.2
  • 14
    • 0018801485 scopus 로고
    • Structural requirements of double-stranded RNA for the activation of 2′,5′-oligo(A) polymerase and protein kinase of interferon-treated HeLa cells
    • MINKS, M.A. et al. 1979. Structural requirements of double-stranded RNA for the activation of 2′,5′-oligo(A) polymerase and protein kinase of interferon-treated HeLa cells. J. Biol. Chem. 254: 10180-10183.
    • (1979) J. Biol. Chem. , vol.254 , pp. 10180-10183
    • Minks, M.A.1
  • 15
    • 0026713151 scopus 로고
    • Interactions between double-stranded RNA regulators and the protein kinase DAI
    • MANCHE, L. et al. 1992. Interactions between double-stranded RNA regulators and the protein kinase DAI. Mol. Cell Biol. 12: 5238-5248.
    • (1992) Mol. Cell Biol. , vol.12 , pp. 5238-5248
    • Manche, L.1
  • 16
    • 0035859929 scopus 로고    scopus 로고
    • Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems
    • CAPLEN, N.J. et al. 2001. Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems. Proc. Natl. Acad. Sci. USA 98: 9742-9747.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 9742-9747
    • Caplen, N.J.1
  • 17
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • ELBASHIR, S.M. et al. 2001. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411: 494-498.
    • (2001) Nature , vol.411 , pp. 494-498
    • Elbashir, S.M.1
  • 18
    • 0034636715 scopus 로고    scopus 로고
    • dsRNA-mediated gene silencing in cultured Drosophila cells: A tissue culture model for the analysis of RNA interference
    • CAPLEN, N.J. et al. 2000. dsRNA-mediated gene silencing in cultured Drosophila cells: a tissue culture model for the analysis of RNA interference. Gene 252: 95-105.
    • (2000) Gene , vol.252 , pp. 95-105
    • Caplen, N.J.1
  • 19
    • 0034612276 scopus 로고    scopus 로고
    • Use of double-stranded RNA interference in drosophila cell lines to dissect signal transduction pathways
    • CLEMENS, J.C. et al. 2000. Use of double-stranded RNA interference in drosophila cell lines to dissect signal transduction pathways. Proc. Natl. Acad. Sci. USA 97: 6499-6503.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 6499-6503
    • Clemens, J.C.1
  • 20
    • 0036351317 scopus 로고    scopus 로고
    • Analysis of gene function in somatic mammalian cells using small interfering RNAs
    • ELBASHIR, S.M. et al. 2002. Analysis of gene function in somatic mammalian cells using small interfering RNAs. Methods 26: 199-213.
    • (2002) Methods , vol.26 , pp. 199-213
    • Elbashir, S.M.1
  • 21
    • 0037089135 scopus 로고    scopus 로고
    • Positional effects of short interfering RNAs targeting the human coagulation trigger tissue factor
    • HOLEN, T. et al. 2002. Positional effects of short interfering RNAs targeting the human coagulation trigger tissue factor. Nucleic Acids Res. 30: 1757-1766.
    • (2002) Nucleic Acids Res. , vol.30 , pp. 1757-1766
    • Holen, T.1
  • 22
    • 0036752785 scopus 로고    scopus 로고
    • RNAi in human cells: Basic structural and functional features of small interfering RNA
    • CHIU, Y.L. & T.M. RANA. 2002. RNAi in human cells: basic structural and functional features of small interfering RNA. Mol. Cell. 10: 549-561.
    • (2002) Mol. Cell. , vol.10 , pp. 549-561
    • Chiu, Y.L.1    Rana, T.M.2
  • 23
    • 0036811055 scopus 로고    scopus 로고
    • Effects on RNA interference in gene expression (RNAi) in cultured mammalian cells of mismatches and the introduction of chemical modifications at the 3′-ends of siRNAs
    • HAMADA, M. et al. 2002. Effects on RNA interference in gene expression (RNAi) in cultured mammalian cells of mismatches and the introduction of chemical modifications at the 3′-ends of siRNAs. Antisense Nucleic Acid Drug Dev. 12: 301-309.
    • (2002) Antisense Nucleic Acid Drug Dev. , vol.12 , pp. 301-309
    • Hamada, M.1
  • 24
    • 0037440005 scopus 로고    scopus 로고
    • Tolerance for mutations and chemical modifications in a siRNA
    • AMARZGUIOUI, M. et al. 2003. Tolerance for mutations and chemical modifications in a siRNA. Nucleic Acids Res. 31: 589-595.
    • (2003) Nucleic Acids Res. , vol.31 , pp. 589-595
    • Amarzguioui, M.1
  • 25
    • 0036074161 scopus 로고    scopus 로고
    • RNA interference in human cells is restricted to the cytoplasm
    • ZENG, Y. & B.R. CULLEN. 2002. RNA interference in human cells is restricted to the cytoplasm. RNA 8: 855-860.
    • (2002) RNA , vol.8 , pp. 855-860
    • Zeng, Y.1    Cullen, B.R.2
  • 26
    • 0037117550 scopus 로고    scopus 로고
    • A DNA vector-based RNAi technology to suppress gene expression in mammalian cells
    • SUI, G. et al. 2002. A DNA vector-based RNAi technology to suppress gene expression in mammalian cells. Proc. Natl. Acad. Sci. USA 99: 5515-5520.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 5515-5520
    • Sui, G.1
  • 27
    • 0037134020 scopus 로고    scopus 로고
    • A system for stable expression of short interfering RNAs in mammalian cells
    • BRUMMELKAMP, T.R., R. BERNARDS & R. AGAMI. 2002. A system for stable expression of short interfering RNAs in mammalian cells. Science 296: 550-553.
    • (2002) Science , vol.296 , pp. 550-553
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3
  • 28
    • 0036273940 scopus 로고    scopus 로고
    • Gene silencing using micro-RNA designed hairpins
    • MCMANUS, M.T. et al. 2002. Gene silencing using micro-RNA designed hairpins. RNA 8: 842-850.
    • (2002) RNA , vol.8 , pp. 842-850
    • Mcmanus, M.T.1
  • 29
    • 0036251639 scopus 로고    scopus 로고
    • Effective expression of small interfering RNA in human cells
    • PAUL, C.P. et al. 2002. Effective expression of small interfering RNA in human cells. Nat. Biotechnol. 20: 505-508.
    • (2002) Nat. Biotechnol. , vol.20 , pp. 505-508
    • Paul, C.P.1
  • 30
    • 0036256430 scopus 로고    scopus 로고
    • Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells
    • LEE, N.S. et al. 2002. Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells. Nat. Biotechnol. 20: 500-505.
    • (2002) Nat. Biotechnol. , vol.20 , pp. 500-505
    • Lee, N.S.1
  • 31
    • 0036245628 scopus 로고    scopus 로고
    • U6 promoter driven siRNAs with four uridine 3′ overhangs efficiently suppress targeted gene expression in mammalian cells
    • MIYAGISHI, M. & K. TAIRA. 2002. U6 promoter driven siRNAs with four uridine 3′ overhangs efficiently suppress targeted gene expression in mammalian cells. Nat. Biotechnol. 20: 497-500.
    • (2002) Nat. Biotechnol. , vol.20 , pp. 497-500
    • Miyagishi, M.1    Taira, K.2
  • 32
    • 0037197914 scopus 로고    scopus 로고
    • RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells
    • Yu, J.Y., S.L. DERUITER & D.L. TURNER. 2002. RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells. Proc. Natl. Acad. Sci. USA 99: 6047-6052.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 6047-6052
    • Yu, J.Y.1    Deruiter, S.L.2    Turner, D.L.3
  • 33
    • 0034676457 scopus 로고    scopus 로고
    • Functional genomic analysis of C. elegans chromosome I by systematic RNA interference
    • FRASER, A.G. et al. 2000. Functional genomic analysis of C. elegans chromosome I by systematic RNA interference. Nature 408: 325-330.
    • (2000) Nature , vol.408 , pp. 325-330
    • Fraser, A.G.1
  • 34
    • 0034676448 scopus 로고    scopus 로고
    • Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III
    • GONCZY, P. et al. 2000. Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III. Nature 408: 331-336.
    • (2000) Nature , vol.408 , pp. 331-336
    • Gonczy, P.1
  • 35
    • 0034649570 scopus 로고    scopus 로고
    • RNAi analysis of genes expressed in the ovary of Caenorhabditis elegans
    • PIANO, F. et al. 2000. RNAi analysis of genes expressed in the ovary of Caenorhabditis elegans. Curr. Biol. 10: 1619-1622.
    • (2000) Curr. Biol. , vol.10 , pp. 1619-1622
    • Piano, F.1
  • 36
    • 0037137443 scopus 로고    scopus 로고
    • Gene clustering based on RNAi phenotypes of ovary-enriched genes in C. elegans
    • PIANO, F. et al. 2002. Gene clustering based on RNAi phenotypes of ovary-enriched genes in C. elegans. Curr. Biol. 12: 1959-1964.
    • (2002) Curr. Biol. , vol.12 , pp. 1959-1964
    • Piano, F.1
  • 37
    • 0037228016 scopus 로고    scopus 로고
    • A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity
    • LEE, S.S. et al. 2003. A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity. Nat. Genet. 33: 40-48.
    • (2003) Nat. Genet. , vol.33 , pp. 40-48
    • Lee, S.S.1
  • 38
    • 0037448540 scopus 로고    scopus 로고
    • Systematic functional analysis of the Caenorhabditis elegans genome using RNAi
    • KAMATH, R.S. et al. 2003. Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature 421: 231-237.
    • (2003) Nature , vol.421 , pp. 231-237
    • Kamath, R.S.1
  • 39
    • 0037448528 scopus 로고    scopus 로고
    • Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes
    • ASHRAFI, K. et al. 2003. Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes. Nature 421: 268-272.
    • (2003) Nature , vol.421 , pp. 268-272
    • Ashrafi, K.1
  • 40
    • 0037443054 scopus 로고    scopus 로고
    • Identification of genes that protect the C. elegans genome against mutations by genome-wide RNAi
    • POTHOF, J. et al. 2003. Identification of genes that protect the C. elegans genome against mutations by genome-wide RNAi. Genes Dev. 17: 443-448.
    • (2003) Genes Dev. , vol.17 , pp. 443-448
    • Pothof, J.1
  • 41
    • 0037470952 scopus 로고    scopus 로고
    • Identification of Hedgehog pathway components by RNAi in Drosophila cultured cells
    • LUM, L. et al. 2003. Identification of Hedgehog pathway components by RNAi in Drosophila cultured cells. Science 299: 2039-2045.
    • (2003) Science , vol.299 , pp. 2039-2045
    • Lum, L.1
  • 42
    • 0037062951 scopus 로고    scopus 로고
    • RNA interference
    • HANNON, G.J. 2002. RNA interference. Nature 418: 244-251.
    • (2002) Nature , vol.418 , pp. 244-251
    • Hannon, G.J.1
  • 43
    • 0036653097 scopus 로고    scopus 로고
    • RNA interference: The new somatic cell genetics?
    • PADDISON, P.J. & G.J. HANNON. 2002. RNA interference: the new somatic cell genetics? Cancer Cell 2: 17-23.
    • (2002) Cancer Cell , vol.2 , pp. 17-23
    • Paddison, P.J.1    Hannon, G.J.2
  • 44
    • 0037441979 scopus 로고    scopus 로고
    • Consortium uses RNAi to uncover genes' function
    • FRANKISH, H. 2003. Consortium uses RNAi to uncover genes' function. Lancet 361: 584.
    • (2003) Lancet , vol.361 , pp. 584
    • Frankish, H.1
  • 45
    • 0037019339 scopus 로고    scopus 로고
    • RNA interference in adult mice
    • MCCAFFREY, A.P. et al. 2002. RNA interference in adult mice. Nature 418: 38-39.
    • (2002) Nature , vol.418 , pp. 38-39
    • Mccaffrey, A.P.1
  • 46
    • 0036727416 scopus 로고    scopus 로고
    • Efficient delivery of siRNA for inhibition of gene expression in postnatal mice
    • LEWIS, D.L. et al. 2002. Efficient delivery of siRNA for inhibition of gene expression in postnatal mice. Nat. Genet. 32: 107-108.
    • (2002) Nat. Genet. , vol.32 , pp. 107-108
    • Lewis, D.L.1
  • 47
    • 0036787671 scopus 로고    scopus 로고
    • siRNA-mediated gene silencing in vitro and in vivo
    • XIA, H. et al. 2002. siRNA-mediated gene silencing in vitro and in vivo. Nat. Biotechnol. 20: 1006-1010.
    • (2002) Nat. Biotechnol. , vol.20 , pp. 1006-1010
    • Xia, H.1
  • 48
    • 0037021437 scopus 로고    scopus 로고
    • Small interfering RNA and gene silencing in transgenic mice and rats
    • HASUWA, H. et al. 2002. Small interfering RNA and gene silencing in transgenic mice and rats. FEBS Lett. 532: 227-230.
    • (2002) FEBS Lett. , vol.532 , pp. 227-230
    • Hasuwa, H.1
  • 49
    • 0037452812 scopus 로고    scopus 로고
    • A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA
    • TISCORNIA, G. et al. 2003. A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA. Proc. Natl. Acad. Sci. USA 100: 1844-1848.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 1844-1848
    • Tiscornia, G.1
  • 50
    • 0037370498 scopus 로고    scopus 로고
    • A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference
    • RUBINSON, D.A. et al. 2003. A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference. Nat. Genet. 33: 401-406.
    • (2003) Nat. Genet. , vol.33 , pp. 401-406
    • Rubinson, D.A.1
  • 51
    • 0037312978 scopus 로고    scopus 로고
    • Germline transmission of RNAi in mice
    • CARMELL, M.A. et al. 2003. Germline transmission of RNAi in mice. Nat. Struct. Biol. 10: 91-92.
    • (2003) Nat. Struct. Biol. , vol.10 , pp. 91-92
    • Carmell, M.A.1
  • 52
    • 0038708339 scopus 로고    scopus 로고
    • Transgenic RNA interference in ES cell-derived embryos recapitulates a genetic null phenotype
    • KUNATH, T. et al. 2003. Transgenic RNA interference in ES cell-derived embryos recapitulates a genetic null phenotype. Nat. Biotechnol. 21: 559-561.
    • (2003) Nat. Biotechnol. , vol.21 , pp. 559-561
    • Kunath, T.1
  • 53
    • 0037377201 scopus 로고    scopus 로고
    • Transgenic RNAi in mouse oocytes: A simple and fast approach to study gene function
    • STEIN, P., P. SVOBODA & R.M. SCHULTZ. 2003. Transgenic RNAi in mouse oocytes: a simple and fast approach to study gene function. Dev. Biol. 256: 188-194.
    • (2003) Dev. Biol. , vol.256 , pp. 188-194
    • Stein, P.1    Svoboda, P.2    Schultz, R.M.3
  • 54
    • 0037081772 scopus 로고    scopus 로고
    • Rescue of polyglutamine-mediated cytotoxicity by double-stranded RNA-mediated RNA interference
    • CAPLEN, N.J. et al. 2002. Rescue of polyglutamine-mediated cytotoxicity by double-stranded RNA-mediated RNA interference. Hum. Mol. Genet. 11: 175-184.
    • (2002) Hum. Mol. Genet. , vol.11 , pp. 175-184
    • Caplen, N.J.1
  • 55
    • 0037441756 scopus 로고    scopus 로고
    • Specific inhibition of bcr-abl gene expression by small interfering RNA
    • SCHERR, M. et al. 2003. Specific inhibition of bcr-abl gene expression by small interfering RNA. Blood 101: 1566-1569.
    • (2003) Blood , vol.101 , pp. 1566-1569
    • Scherr, M.1
  • 56
    • 0037158901 scopus 로고    scopus 로고
    • Killing of leukemic cells with a BCR/ABL fusion gene by RNA interference (RNAi)
    • WILDA, M. et al. 2002. Killing of leukemic cells with a BCR/ABL fusion gene by RNA interference (RNAi). Oncogene 21: 5716-5724.
    • (2002) Oncogene , vol.21 , pp. 5716-5724
    • Wilda, M.1
  • 57
    • 0036726313 scopus 로고    scopus 로고
    • Stable suppression of tumorigenicity by virus-mediated RNA interference
    • BRUMMELKAMP, T.R., R. BERNARDS & R. AGAMI. 2002. Stable suppression of tumorigenicity by virus-mediated RNA interference. Cancer Cell 2: 243-247.
    • (2002) Cancer Cell , vol.2 , pp. 243-247
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3
  • 58
    • 0344211452 scopus 로고    scopus 로고
    • Vector-based RNAi, a novel tool for isoform-specific knockdown of VEGF and anti-angiogenesis gene therapy of cancer
    • ZHANG, L. et al. 2003. Vector-based RNAi, a novel tool for isoform-specific knockdown of VEGF and anti-angiogenesis gene therapy of cancer. Biochem. Biophys. Res. Commun. 303: 1169-1178.
    • (2003) Biochem. Biophys. Res. Commun. , vol.303 , pp. 1169-1178
    • Zhang, L.1
  • 59
    • 0037446068 scopus 로고    scopus 로고
    • Small interfering RNAs suppress the expression of endogenous and GFP-fused epidermal growth factor receptor (erbB1) and induce apoptosis in erbB1-overexpressing cells
    • NAGY, P., D.J. ARNDT-JOVIN & T.M. JOVIN. 2003. Small interfering RNAs suppress the expression of endogenous and GFP-fused epidermal growth factor receptor (erbB1) and induce apoptosis in erbB1-overexpressing cells. Exp. Cell Res. 285: 39-49.
    • (2003) Exp. Cell Res. , vol.285 , pp. 39-49
    • Nagy, P.1    Arndt-Jovin, D.J.2    Jovin, T.M.3
  • 60
    • 0037380839 scopus 로고    scopus 로고
    • Small interfering RNA-induced suppression of MDR1 (P-glycoprotein) restores sensitivity to multidrug-resistant cancer cells
    • Wu, H., W.N. HAIT & J.M. YANG. 2003. Small interfering RNA-induced suppression of MDR1 (P-glycoprotein) restores sensitivity to multidrug-resistant cancer cells. Cancer Res. 63: 1515-1519.
    • (2003) Cancer Res. , vol.63 , pp. 1515-1519
    • Wu, H.1    Hait, W.N.2    Yang, J.M.3
  • 61
    • 37049183697 scopus 로고
    • Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
    • SLAMON, D.J. et al. 1987. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 235: 177-182.
    • (1987) Science , vol.235 , pp. 177-182
    • Slamon, D.J.1
  • 62
    • 0032850677 scopus 로고    scopus 로고
    • Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease
    • COBLEIGH, M.A. et al. 1999. Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease. J. Clin. Oncol. 17(9): 2639-2648.
    • (1999) J. Clin. Oncol. , vol.17 , Issue.9 , pp. 2639-2648
    • Cobleigh, M.A.1
  • 63
    • 0035869407 scopus 로고    scopus 로고
    • Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that over expresses HER2
    • SLAMON, D.J. et al. 2001. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that over expresses HER2. N. Engl. J. Med. 344(11): 783-792.
    • (2001) N. Engl. J. Med. , vol.344 , Issue.11 , pp. 783-792
    • Slamon, D.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.