Increasing resistance of tubular epithelial cells to apoptosis by shRNA therapy ameliorates renal ischemia-reperfusion injury

American Journal of Transplantation

Volumn 6, Issue 10, 2006, Pages 2256-2267

  Du, C ^a,c   Wang, S ^a   Diao, H ^a   Guan, Q ^c   Zhong, R ^a,b,c   Jevnikar, A M ^a,b,c  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b ROBARTS RESEARCH INSTITUTE   (Canada)

^c LONDON HEALTH SCIENCES CENTRE   (Canada)

Author keywords

Aptosis; Caspase 8; Fas; Ischemia reperfusion; Kidney failure; shRNA

Indexed keywords

CASPASE 8; CREATININE; FAS ANTIBODY; FAS LIGAND; GAMMA INTERFERON; SHORT HAIRPIN RNA; SUPEROXIDE; TUMOR NECROSIS FACTOR ALPHA; UREA;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTERY CLAMP; ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DNA VECTOR; DOWN REGULATION; DRUG INHIBITION; DRUG MECHANISM; EPITHELIUM CELL; EXPRESSION VECTOR; GENE SILENCING; GENE TARGETING; INFERIOR CAVA VEIN; KIDNEY ISCHEMIA; KIDNEY TUBULE CELL; MALE; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; NONVIRAL GENE THERAPY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RENAL ARTERY; REPERFUSION INJURY; RNA INTERFERENCE; UNINEPHRECTOMY; UREA NITROGEN BLOOD LEVEL;

ANIMALS; ANTIGENS, CD95; APOPTOSIS; CASPASE 8; DISEASE MODELS, ANIMAL; GENE EXPRESSION; KIDNEY TRANSPLANTATION; KIDNEY TUBULES; MALE; MICE; MICE, INBRED C57BL; REPERFUSION INJURY; RNA, SMALL INTERFERING; TREATMENT OUTCOME;

EID: 33748510411     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2006.01478.x     Document Type: Article

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