Lentivirus-mediated transfer of MMP-9 shRNA provides neuroprotection following focal ischemic brain injury in rats

Brain Research

Volumn 1367, Issue , 2011, Pages 347-359

  Hu, Qin ^a,b,c   Chen, Chunhua ^a   Khatibi, Nikan H ^b   Li, Li ^a   Yang, Lei ^a   Wang, Ke ^a   Han, Jingyan ^a   Duan, Weiming ^c   Zhang, John H ^b   Zhou, Changman ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b LOMA LINDA UNIVERSITY   (United States)

^c CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Blood brain barrier (BBB); Brain edema; Lentivirus; Middle cerebral artery occlusion (MCAO); MMP 9; shRNA

Indexed keywords

GELATINASE B; SHORT HAIRPIN RNA; VIRUS VECTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD BRAIN BARRIER; BRAIN ISCHEMIA; CELL DEATH; LENTIVIRINAE; NERVE CELL; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT;

ANALYSIS OF VARIANCE; ANIMALS; BLOOD-BRAIN BARRIER; CELL LINE, TRANSFORMED; CELLS, CULTURED; DISEASE MODELS, ANIMAL; EVANS BLUE; GENE EXPRESSION REGULATION; GENE TRANSFER TECHNIQUES; INFARCTION, MIDDLE CEREBRAL ARTERY; LENTIVIRUS; MALE; MATRIX METALLOPROTEINASE 9; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; RNA, SMALL INTERFERING; SINGLE-BLIND METHOD; TETRAZOLIUM SALTS; TRAUMA SEVERITY INDICES;

LENTIVIRUS; RATTUS;

EID: 78650515010     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2010.10.002     Document Type: Article

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