Synthetic peroxides as potent antimalarials. News and views

Current Topics in Medicinal Chemistry

Volumn 12, Issue 5, 2012, Pages 373-399

  Jefford, Charles W ^a,b  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b NONE   (Switzerland)

Author keywords

Artemisinin; Dioxane; Dioxolane; Ferrous ion; Heme; Hybrid; Peroxide; SERCA; Tetraoxane; Trioxane; Trioxolane

Indexed keywords

1,2,4 TRIOXANE DERIVATIVE; 1,3 DIOXOLANE DERIVATIVE; ADAMANTANE; AMINOQUINOLINE DERIVATIVE; ANTIMALARIAL AGENT; ARTEMETHER; ARTEMISININ; ARTESUNATE; CHLOROQUINE; DEFEROXAMINE; FERROUS ASPARTATE; FERROUS CHLORIDE; FERROUS GLUCONATE; FERROUS ION; FERROUS SULFATE; HEME; HEMOGLOBIN; SACCHAROMYCES CEREVISIAE PROTEIN; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; SYNTHETIC CYCLIC PEROXIDE; TETRAOXANE DERIVATIVE; THAPSIGARGIN; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; CHIRALITY; DRUG ACTIVITY; DRUG BINDING; DRUG BIOAVAILABILITY; DRUG DESIGN; DRUG EFFICACY; DRUG FORMULATION; DRUG MIXTURE; DRUG POTENCY; DRUG RESISTANCE; DRUG SCREENING; ENANTIOMER; ENDOPLASMIC RETICULUM; ENZYME INHIBITION; EPOXIDATION; GENE REARRANGEMENT; HYBRID; IC 50; ISOMERIZATION; MOLECULE; NONHUMAN; OOCYTE; PHARMACOPHORE; PHOTOOXIDATION; PLASMODIUM; PLASMODIUM FALCIPARUM; PLASMODIUM YOELII; PROTEIN EXPRESSION; PROTEIN PURIFICATION; REVIEW; SACCHAROMYCES CEREVISIAE; THERMODYNAMICS; XENOPUS;

EID: 84857752045     PISSN: 15680266     EISSN: 18734294     Source Type: Journal    
DOI: 10.2174/156802612799362940     Document Type: Review

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