Second-generation antimalarial endoperoxides

Parasitology Today

Volumn 12, Issue 2, 1996, Pages 79-82

  Meshnick, Steven R ^a   Jefford, Charles W ^b   Posner, Gary H ^c   Avery, Mitchell A ^d   Peters, Wallace ^e  

^a UNIVERSITY OF MICHIGAN SCHOOL OF PUBLIC HEALTH   (United States)

^b UNIVERSITY OF GENEVA   (Switzerland)

^c JOHNS HOPKINS UNIVERSITY   (United States)

^d UNIVERSITY OF MISSISSIPPI   (United States)

^e CAB International Institute of Parasitology   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMALARIAL AGENT; ARTEMISIN; PEROXIDE;

MALARIA; NONHUMAN; SHORT SURVEY;

EID: 0030051699     PISSN: 01694758     EISSN: None     Source Type: Journal    
DOI: 10.1016/0169-4758(96)80660-0     Document Type: Article

References (14)

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3. Asawamahasakda, W. et al. (1994) Alkylation of parasite-specific proteins by endoperoxide antimalarials. Antimicrob. Agents Chemother. 38, 1854-1858
4. Posner, G.H. and Oh, C.H. (1992) A regiospecifically oxygen-18 labeled 1,2,4-trioxane: a simple chemical model system to probe the mechanism(s) for the antimalarial activity of artemisinin (Qinghaosu). J. Am. Chem. Soc. 114, 8328-8329
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